ZA200102380B - Methods and compositions for inhibiting neoplastic cell growth. - Google Patents
Methods and compositions for inhibiting neoplastic cell growth. Download PDFInfo
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- ZA200102380B ZA200102380B ZA200102380A ZA200102380A ZA200102380B ZA 200102380 B ZA200102380 B ZA 200102380B ZA 200102380 A ZA200102380 A ZA 200102380A ZA 200102380 A ZA200102380 A ZA 200102380A ZA 200102380 B ZA200102380 B ZA 200102380B
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- 229940063683 taxotere Drugs 0.000 description 1
- NRUKOCRGYNPUPR-QBPJDGROSA-N teniposide Chemical compound COC1=C(O)C(OC)=CC([C@@H]2C3=CC=4OCOC=4C=C3[C@@H](O[C@H]3[C@@H]([C@@H](O)[C@@H]4O[C@@H](OC[C@H]4O3)C=3SC=CC=3)O)[C@@H]3[C@@H]2C(OC3)=O)=C1 NRUKOCRGYNPUPR-QBPJDGROSA-N 0.000 description 1
- 229960001278 teniposide Drugs 0.000 description 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 1
- 238000011285 therapeutic regimen Methods 0.000 description 1
- CNHYKKNIIGEXAY-UHFFFAOYSA-N thiolan-2-imine Chemical compound N=C1CCCS1 CNHYKKNIIGEXAY-UHFFFAOYSA-N 0.000 description 1
- RYYWUUFWQRZTIU-UHFFFAOYSA-K thiophosphate Chemical compound [O-]P([O-])([O-])=S RYYWUUFWQRZTIU-UHFFFAOYSA-K 0.000 description 1
- 229960001196 thiotepa Drugs 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 229960002175 thyroglobulin Drugs 0.000 description 1
- 201000002510 thyroid cancer Diseases 0.000 description 1
- 210000001685 thyroid gland Anatomy 0.000 description 1
- 229940034208 thyroxine Drugs 0.000 description 1
- XUIIKFGFIJCVMT-UHFFFAOYSA-N thyroxine-binding globulin Natural products IC1=CC(CC([NH3+])C([O-])=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-UHFFFAOYSA-N 0.000 description 1
- 230000036964 tight binding Effects 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 108091006106 transcriptional activators Proteins 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 239000012096 transfection reagent Substances 0.000 description 1
- 238000000844 transformation Methods 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 239000002753 trypsin inhibitor Substances 0.000 description 1
- 230000004565 tumor cell growth Effects 0.000 description 1
- 102000003390 tumor necrosis factor Human genes 0.000 description 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 210000003932 urinary bladder Anatomy 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 108700026220 vif Genes Proteins 0.000 description 1
- GBABOYUKABKIAF-GHYRFKGUSA-N vinorelbine Chemical compound C1N(CC=2C3=CC=CC=C3NC=22)CC(CC)=C[C@H]1C[C@]2(C(=O)OC)C1=CC([C@]23[C@H]([C@]([C@H](OC(C)=O)[C@]4(CC)C=CCN([C@H]34)CC2)(O)C(=O)OC)N2C)=C2C=C1OC GBABOYUKABKIAF-GHYRFKGUSA-N 0.000 description 1
- 229960002066 vinorelbine Drugs 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 238000003260 vortexing Methods 0.000 description 1
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- 239000012138 yeast extract Substances 0.000 description 1
- 229910052727 yttrium Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10408098P | 1998-10-13 | 1998-10-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200102380B true ZA200102380B (en) | 2002-03-22 |
Family
ID=22298575
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200102380A ZA200102380B (en) | 1998-10-13 | 1999-10-05 | Methods and compositions for inhibiting neoplastic cell growth. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1121439B1 (fr) |
JP (1) | JP2002527452A (fr) |
KR (2) | KR100448427B1 (fr) |
AT (2) | ATE332970T1 (fr) |
AU (1) | AU758462B2 (fr) |
CA (1) | CA2344465A1 (fr) |
DE (2) | DE69932342T2 (fr) |
DK (2) | DK1121439T3 (fr) |
ES (2) | ES2268901T3 (fr) |
IL (3) | IL142088A0 (fr) |
MX (1) | MXPA01003636A (fr) |
NZ (1) | NZ510584A (fr) |
PT (2) | PT1121439E (fr) |
WO (1) | WO2000021996A2 (fr) |
ZA (1) | ZA200102380B (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7169906B2 (en) | 1997-09-17 | 2007-01-30 | Genentech, Inc. | PRO211 polypeptides |
US6974689B1 (en) | 1997-09-18 | 2005-12-13 | Genentech, Inc. | Nucleic acid encoding PRO211 polypeptides |
CA2406855A1 (fr) * | 2000-04-21 | 2001-11-01 | Takeda Chemical Industries, Ltd. | Nouveaux polypeptides appartenant a la famille insuline/igf/relaxine et adn correspondants |
CA2710775A1 (fr) * | 2007-12-28 | 2009-07-09 | Bioinvent International Ab | Formulation |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ226799A (en) * | 1987-11-06 | 1991-08-27 | Oncogen | Breast cancer inhibitory factor and method for inhibiting proliferation of neoplastic cells and compositions therefor |
US5814307A (en) * | 1989-04-10 | 1998-09-29 | Bristol-Myers Squibb Company | Method for regulating cell growth, leukocyte differentiation and tumor cell growth using Oncostatin M to stimulate synthesis of IL-6 |
US5416192A (en) * | 1990-04-03 | 1995-05-16 | Bristol-Myers Squibb Company | Epithelins: novel cysteine-rich growth modulating proteins |
AU9312198A (en) * | 1997-09-17 | 1999-04-05 | Genentech Inc. | Genes amplified in tumours, antibodies against the proteins encoded thereby, andtheir use in diagnosis and treatment of cancer |
NZ503343A (en) * | 1997-09-17 | 2002-09-27 | Genentech Inc | Secreted and transmembrane polypeptides and use to induce apoptosis of tumour cells |
-
1999
- 1999-10-05 ES ES99970398T patent/ES2268901T3/es not_active Expired - Lifetime
- 1999-10-05 KR KR10-2003-7014739A patent/KR100448427B1/ko not_active IP Right Cessation
- 1999-10-05 ES ES04025897T patent/ES2290606T3/es not_active Expired - Lifetime
- 1999-10-05 DK DK99970398T patent/DK1121439T3/da active
- 1999-10-05 PT PT99970398T patent/PT1121439E/pt unknown
- 1999-10-05 DE DE69932342T patent/DE69932342T2/de not_active Expired - Lifetime
- 1999-10-05 AT AT99970398T patent/ATE332970T1/de active
- 1999-10-05 MX MXPA01003636A patent/MXPA01003636A/es active IP Right Grant
- 1999-10-05 EP EP99970398A patent/EP1121439B1/fr not_active Expired - Lifetime
- 1999-10-05 ZA ZA200102380A patent/ZA200102380B/en unknown
- 1999-10-05 WO PCT/US1999/023089 patent/WO2000021996A2/fr active Application Filing
- 1999-10-05 AU AU12005/00A patent/AU758462B2/en not_active Expired
- 1999-10-05 KR KR10-2001-7004627A patent/KR100448426B1/ko not_active IP Right Cessation
- 1999-10-05 NZ NZ510584A patent/NZ510584A/xx not_active IP Right Cessation
- 1999-10-05 AT AT04025897T patent/ATE363536T1/de active
- 1999-10-05 CA CA002344465A patent/CA2344465A1/fr not_active Abandoned
- 1999-10-05 IL IL14208899A patent/IL142088A0/xx active IP Right Grant
- 1999-10-05 DE DE69936234T patent/DE69936234T2/de not_active Expired - Lifetime
- 1999-10-05 JP JP2000575898A patent/JP2002527452A/ja active Pending
- 1999-10-05 DK DK04025897T patent/DK1518930T3/da active
- 1999-10-05 PT PT04025897T patent/PT1518930E/pt unknown
-
2001
- 2001-03-19 IL IL142088A patent/IL142088A/en not_active IP Right Cessation
-
2008
- 2008-02-13 IL IL189502A patent/IL189502A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE69932342D1 (de) | 2006-08-24 |
DK1518930T3 (da) | 2007-10-01 |
IL189502A0 (en) | 2008-06-05 |
ES2268901T3 (es) | 2007-03-16 |
IL142088A (en) | 2008-11-26 |
EP1121439A2 (fr) | 2001-08-08 |
JP2002527452A (ja) | 2002-08-27 |
PT1121439E (pt) | 2006-12-29 |
WO2000021996A2 (fr) | 2000-04-20 |
DE69936234D1 (de) | 2007-07-12 |
KR100448427B1 (ko) | 2004-09-16 |
AU1200500A (en) | 2000-05-01 |
ATE332970T1 (de) | 2006-08-15 |
ATE363536T1 (de) | 2007-06-15 |
PT1518930E (pt) | 2007-09-04 |
AU758462B2 (en) | 2003-03-20 |
CA2344465A1 (fr) | 2000-04-20 |
MXPA01003636A (es) | 2003-10-14 |
KR20010085915A (ko) | 2001-09-07 |
DE69932342T2 (de) | 2007-07-12 |
IL142088A0 (en) | 2002-03-10 |
ES2290606T3 (es) | 2008-02-16 |
WO2000021996A3 (fr) | 2000-11-09 |
KR100448426B1 (ko) | 2004-09-13 |
KR20030096387A (ko) | 2003-12-24 |
NZ510584A (en) | 2003-04-29 |
EP1121439B1 (fr) | 2006-07-12 |
DK1121439T3 (da) | 2006-11-13 |
DE69936234T2 (de) | 2008-03-06 |
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