YU87201A - Postupak za nishodnu regulaciju gdf-8 aktivnosti - Google Patents

Postupak za nishodnu regulaciju gdf-8 aktivnosti

Info

Publication number
YU87201A
YU87201A YU87201A YUP87201A YU87201A YU 87201 A YU87201 A YU 87201A YU 87201 A YU87201 A YU 87201A YU P87201 A YUP87201 A YU P87201A YU 87201 A YU87201 A YU 87201A
Authority
YU
Yugoslavia
Prior art keywords
gdf
methods
analogs
homologues
nucleic acid
Prior art date
Application number
YU87201A
Other languages
English (en)
Inventor
Torben Halkier
Soren Mouritsen
Steen Klysner
Original Assignee
Pharmexa A/S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmexa A/S. filed Critical Pharmexa A/S.
Publication of YU87201A publication Critical patent/YU87201A/sh

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Otkriveni su novi postupci za povećanje mišićne mase pomoću imunizacije na Faktor Diferencijacije Rasta 8 (GDF-8, miostatin). Imunizacija se poželjno izvodi primenom analoga GDF-8 koji su sposobni da indukuju proizvodnju antitela na homologi GDF-8. Posebno poželjan kao imunogen je homologi GDF-8 koji je modifikovan introdukcijom jednog ili nekoliko stranih, imunodominantnih i raznorodnih T-ćelijskih epitopa dok je znatno očuvana tercijarna struktura homologog GDF-8. Takodje su otkrivene vakcinacije sa nukleinskim klselinama protiv GDF-8 i vakcinacije koje koriste žive vakcine kao i postupci i sredstva korisni za vakcinaciju. Takvi postupci i sredstva obuhvataju postupke za identifikaciju korisnih imunogenih GDF-8 analoga, postupke za pripremanje analoga i farmaceutskih formulacija, kao i fragmente nukleinskih kiselina, vektore, transformisane ćelije, polipeptide i farmaceutske formulacije.
YU87201A 1999-07-20 2000-07-20 Postupak za nishodnu regulaciju gdf-8 aktivnosti YU87201A (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199901014 1999-07-20
US14527599P 1999-07-26 1999-07-26

Publications (1)

Publication Number Publication Date
YU87201A true YU87201A (sh) 2004-09-03

Family

ID=44359331

Family Applications (1)

Application Number Title Priority Date Filing Date
YU87201A YU87201A (sh) 1999-07-20 2000-07-20 Postupak za nishodnu regulaciju gdf-8 aktivnosti

Country Status (4)

Country Link
AR (1) AR024808A1 (sh)
MY (1) MY135691A (sh)
PE (1) PE20010479A1 (sh)
YU (1) YU87201A (sh)

Also Published As

Publication number Publication date
AR024808A1 (es) 2002-10-23
MY135691A (en) 2008-06-30
PE20010479A1 (es) 2001-04-24

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