YU82482A - Process for obtaining racemic and optically active new 5-substituted 4-oxo-pgi1 derivatives - Google Patents

Process for obtaining racemic and optically active new 5-substituted 4-oxo-pgi1 derivatives

Info

Publication number
YU82482A
YU82482A YU00824/82A YU82482A YU82482A YU 82482 A YU82482 A YU 82482A YU 00824/82 A YU00824/82 A YU 00824/82A YU 82482 A YU82482 A YU 82482A YU 82482 A YU82482 A YU 82482A
Authority
YU
Yugoslavia
Prior art keywords
pgi1
oxo
derivatives
substituted
optically active
Prior art date
Application number
YU00824/82A
Other languages
English (en)
Inventor
V Simonidesz
J Ivanics
G Galambos
A Papp
G Kovacs
J Skopal
I Szilagyi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of YU82482A publication Critical patent/YU82482A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
YU00824/82A 1981-04-14 1982-04-14 Process for obtaining racemic and optically active new 5-substituted 4-oxo-pgi1 derivatives YU82482A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU81965A HU184948B (en) 1981-04-14 1981-04-14 Process for preparing 5-substituted 4-oxo-pgi down 1 derivatives

Publications (1)

Publication Number Publication Date
YU82482A true YU82482A (en) 1985-04-30

Family

ID=10952241

Family Applications (1)

Application Number Title Priority Date Filing Date
YU00824/82A YU82482A (en) 1981-04-14 1982-04-14 Process for obtaining racemic and optically active new 5-substituted 4-oxo-pgi1 derivatives

Country Status (15)

Country Link
US (1) US4520018A (xx)
EP (1) EP0063323B1 (xx)
JP (1) JPS57183779A (xx)
AT (1) AT381303B (xx)
CS (1) CS228922B2 (xx)
DD (1) DD202156A5 (xx)
DE (1) DE3267104D1 (xx)
DK (1) DK165682A (xx)
FI (1) FI821283L (xx)
GR (1) GR78086B (xx)
HU (1) HU184948B (xx)
IL (1) IL65490A (xx)
PL (1) PL129640B1 (xx)
SU (1) SU1189335A3 (xx)
YU (1) YU82482A (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179082A (en) * 1990-11-13 1993-01-12 Merck & Co., Inc. Method for blocking platelet adhesion to collagen
HU231203B1 (hu) * 2011-12-21 2021-10-28 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Új eljárás travoprost előállítására

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795200A (fr) * 1972-05-10 1973-08-09 Ciba Geigy Nouveaux oxabicyclooctanes et leurs procedes de preparation
US4126744A (en) * 1977-12-05 1978-11-21 The Upjohn Company 4-Oxo-PGI1 compounds
US4258199A (en) * 1978-03-13 1981-03-24 Research Corporation Method for preparing cyclic ethers and thioethers including oxygen isomers and sulfur analogs of prostacyclin
HU179001B (en) * 1978-05-29 1982-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 5-halo-6,9alpha-oxido-prostaglandin derivatives
US4330553A (en) * 1979-11-12 1982-05-18 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Oxo-PGI2 -derivatives and process for the preparation thereof and pharmaceutical compositions containing same
EP0059307A1 (de) * 1981-02-26 1982-09-08 Grünenthal GmbH Verfahren zur Herstellung von 2-Oxabicyclo(3.3.0)octanderivaten und danach erhältliche Produkte
HU184949B (en) * 1981-04-14 1984-11-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing 4-oxo-pgi down 2 and analogues thereof

Also Published As

Publication number Publication date
DK165682A (da) 1982-10-15
HU184948B (en) 1984-11-28
DE3267104D1 (en) 1985-12-05
DD202156A5 (de) 1983-08-31
EP0063323A1 (de) 1982-10-27
ATA139082A (de) 1986-02-15
JPS57183779A (en) 1982-11-12
EP0063323B1 (de) 1985-10-30
AT381303B (de) 1986-09-25
IL65490A (en) 1985-11-29
IL65490A0 (en) 1982-07-30
FI821283L (fi) 1982-10-15
FI821283A0 (fi) 1982-04-13
PL235964A1 (en) 1983-01-17
SU1189335A3 (ru) 1985-10-30
GR78086B (xx) 1984-09-26
US4520018A (en) 1985-05-28
PL129640B1 (en) 1984-05-31
CS228922B2 (en) 1984-05-14

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