YU19701A - Postupak za regulisanje na niže osteoprotegerinske ligandne aktivnosti - Google Patents
Postupak za regulisanje na niže osteoprotegerinske ligandne aktivnostiInfo
- Publication number
- YU19701A YU19701A YU19701A YU19701A YU19701A YU 19701 A YU19701 A YU 19701A YU 19701 A YU19701 A YU 19701A YU 19701 A YU19701 A YU 19701A YU 19701 A YU19701 A YU 19701A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- opgl
- osteoprotegerin ligand
- regulating
- nucleic acids
- ligand activity
- Prior art date
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Pronalazak obezbedjuje novi postupak za snižavanje na niže aktivnosti osteoprotegerin lignada (OPGL, TRANCE) čime se omogućava tretiranje/ublažavanje obolenja koja su okarakterisana pomoću suvišnog gubitka koštane mase, na primer, osteoporoze. Regulisanje na niže se vrši pomoću indukovanja imunog odgovora protiv OPGL kod individue koja to treba. Imuni odgovori mogu da budu uvećani pomoću klasične imunizacije sa imunogenim varijantama OPGL ili pomoću nukleinsko kiselinske imunizacije gde nukleinske kiseline kodiraju OPGL varijantu. Pronalazak takodje se odnosi na preparate, polipeptide i nukleinske kiseline koje su primenljive u pronalasku kao i u vektorima i transformisane ćelije koje su primenljive u njihovom dobijanju.[The invention provides a novel method for down-regulating the biological activity of osteoprotegerin ligand (OPGL, TRANCE) thereby rendering possible the treatment/amelioration of diseases characterized by excessive loss of bone mass, e.g. osteoporosis. Down- regulation is effected by inducing an immune response against OPGL in an individual in need thereof. Immune responses can be raised by classical immunization with immunogenic variants of OPGL or by nucleic acid immunization where the nucleic acids encode the OPGL variant. The invention also pertains to compositions, polypeptides and nucleic acids useful in the invention, as well as to vectors and transformed host cells useful in the preparation thereof.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199801164 | 1998-09-15 | ||
| US10289698P | 1998-10-02 | 1998-10-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU19701A true YU19701A (sh) | 2005-06-10 |
| RS49960B RS49960B (sr) | 2008-09-29 |
Family
ID=27675500
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN101260152A (sh) |
| EA (1) | EA006940B1 (sh) |
| RS (1) | RS49960B (sh) |
| ZA (1) | ZA200102131B (sh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019061297A1 (zh) * | 2017-09-29 | 2019-04-04 | 苏州工业园区唯可达生物科技有限公司 | 一种cd4辅助性t细胞表位融合肽及其疫苗 |
| CN110923266A (zh) * | 2019-11-07 | 2020-03-27 | 苏州工业园区唯可达生物科技有限公司 | 一种重组病毒载体、包含其的免疫组合物以及用途 |
-
1999
- 1999-09-13 EA EA200100356A patent/EA006940B1/ru not_active IP Right Cessation
- 1999-09-13 CN CNA2007101927772A patent/CN101260152A/zh active Pending
- 1999-09-13 RS YUP-197/01A patent/RS49960B/sr unknown
-
2001
- 2001-03-14 ZA ZA200102131A patent/ZA200102131B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200102131B (en) | 2002-06-14 |
| EA006940B1 (ru) | 2006-06-30 |
| RS49960B (sr) | 2008-09-29 |
| EA200100356A1 (ru) | 2001-08-27 |
| CN101260152A (zh) | 2008-09-10 |
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