YU19701A - Method for down-regulating osteoprotegerin ligand activity - Google Patents

Method for down-regulating osteoprotegerin ligand activity

Info

Publication number
YU19701A
YU19701A YU19701A YU19701A YU19701A YU 19701 A YU19701 A YU 19701A YU 19701 A YU19701 A YU 19701A YU 19701 A YU19701 A YU 19701A YU 19701 A YU19701 A YU 19701A
Authority
YU
Yugoslavia
Prior art keywords
opgl
osteoprotegerin ligand
regulating
nucleic acids
ligand activity
Prior art date
Application number
YU19701A
Other languages
Serbo-Croatian (sh)
Inventor
Torben Halkier
Jesper Haaning
Original Assignee
Pharmexa A/S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmexa A/S. filed Critical Pharmexa A/S.
Publication of YU19701A publication Critical patent/YU19701A/en
Publication of RS49960B publication Critical patent/RS49960B/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention provides a novel method for down-regulating the biological activity of osteoprotegerin ligand (OPGL, TRANCE) thereby rendering possible the treatment/amelioration of diseases characterized by excessive loss of bone mass, e.g. osteoporosis. Down- regulation is effected by inducing an immune response against OPGL in an individual in need thereof. Immune responses can be raised by classical immunization with immunogenic variants of OPGL or by nucleic acid immunization where the nucleic acids encode the OPGL variant. The invention also pertains to compositions, polypeptides and nucleic acids useful in the invention, as well as to vectors and transformed host cells useful in the preparation thereof.
YUP-197/01A 1998-09-15 1999-09-13 Method for down-regulating osteoprotegerin ligand activity RS49960B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199801164 1998-09-15
US10289698P 1998-10-02 1998-10-02

Publications (2)

Publication Number Publication Date
YU19701A true YU19701A (en) 2005-06-10
RS49960B RS49960B (en) 2008-09-29

Family

ID=27675500

Country Status (4)

Country Link
CN (1) CN101260152A (en)
EA (1) EA006940B1 (en)
RS (1) RS49960B (en)
ZA (1) ZA200102131B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019061297A1 (en) * 2017-09-29 2019-04-04 苏州工业园区唯可达生物科技有限公司 Cd4 helper t-cell epitope fusion peptide and vaccine thereof
CN110923266A (en) * 2019-11-07 2020-03-27 苏州工业园区唯可达生物科技有限公司 Recombinant virus vector, immune composition containing same and application

Also Published As

Publication number Publication date
RS49960B (en) 2008-09-29
ZA200102131B (en) 2002-06-14
EA006940B1 (en) 2006-06-30
EA200100356A1 (en) 2001-08-27
CN101260152A (en) 2008-09-10

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