WO2024082609A1 - 一种生物活性肽的制备装置 - Google Patents

一种生物活性肽的制备装置 Download PDF

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Publication number
WO2024082609A1
WO2024082609A1 PCT/CN2023/092480 CN2023092480W WO2024082609A1 WO 2024082609 A1 WO2024082609 A1 WO 2024082609A1 CN 2023092480 W CN2023092480 W CN 2023092480W WO 2024082609 A1 WO2024082609 A1 WO 2024082609A1
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WIPO (PCT)
Prior art keywords
fixedly mounted
rod
preparation box
mounting
rods
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PCT/CN2023/092480
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English (en)
French (fr)
Inventor
张强
牟雪姣
孙玉军
马玉涵
王松华
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安徽科技学院
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Application filed by 安徽科技学院 filed Critical 安徽科技学院
Publication of WO2024082609A1 publication Critical patent/WO2024082609A1/zh

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18—Stationary reactors having moving elements inside
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D33/00—Filters with filtering elements which move during the filtering operation
    • B01D33/01—Filters with filtering elements which move during the filtering operation with translationally moving filtering elements, e.g. pistons
    • B01D33/015—Filters with filtering elements which move during the filtering operation with translationally moving filtering elements, e.g. pistons with flat filtering elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D33/00—Filters with filtering elements which move during the filtering operation
    • B01D33/44—Regenerating the filter material in the filter
    • B01D33/46—Regenerating the filter material in the filter by scrapers, brushes nozzles or the like acting on the cake-side of the filtering element
    • B01D33/466—Regenerating the filter material in the filter by scrapers, brushes nozzles or the like acting on the cake-side of the filtering element scrapers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length

Definitions

  • the invention relates to the technical field of active peptide preparation, in particular to a preparation device for bioactive peptides.
  • the Chinese authorized utility model patent document with patent number CN216445271U discloses a preparation device for bioactive peptides, comprising a bottom plate, a kettle body is arranged on the top of the bottom plate, a cover body is arranged on the top of the kettle body, a lifting mechanism is arranged on the kettle body, and a stirring mechanism is arranged at the bottom end of the kettle body;
  • the third positive and negative motor drives the carrier frame to move up and down in the vertical direction while rotating with the stirring blade through the threaded shaft, thereby avoiding clogging caused by static filtering of the first filter screen;
  • the preparation device still has the following shortcomings during use: the rotation of the first filtering mechanism is achieved by utilizing the rotation of the stirring blade, but the stirring blade is relatively small in width relative to the kettle body, and the width of the stirring blade in contact with the first filtering mechanism is also small, so it cannot meet the use requirements well (it can move up and down in the vertical direction while rotating).
  • the purpose of the present invention is to solve the problems raised in the background technology and to propose a preparation device for bioactive peptides.
  • a preparation device for bioactive peptides comprising a preparation box mounted on a support frame, a mesh cover with two ends connected is fixedly mounted in the preparation box, a plurality of mounting rods are mounted in the preparation box through a sliding support component, a plurality of mixing rods are fixedly mounted on each of the mounting rods, a mounting block is fixedly mounted on the outside of the mesh cover through a plurality of cross bars, a stirring plate is mounted between corresponding two mounting blocks through a rotating shaft, and a transmission structure is installed between the plurality of mounting rods and the plurality of gears;
  • a plurality of blocks are fixedly installed at the bottom of the mesh cover, a servo motor is fixedly installed at the lower end surface of the preparation box, a shaft body is fixedly installed at the driving end of the servo motor, a second inner gear ring is fixedly installed between the plurality of mounting rods, and a second gear meshing with the second inner gear ring is fixedly installed on the shaft body;
  • a screw is rotatably installed in the preparation box, a gear 3 meshing with the gear 2 is fixedly installed on the screw, and a mesh plate is installed on the screw via a ball nut;
  • a square rod is fixedly installed on the upper end of the screw rod, a circular hole is opened on the upper end of the preparation box, a vertical rod is installed on the square rod through a linkage assembly, a scraper rod is fixedly installed on the lower end of the vertical rod, and a discharge pipe with a valve is fixedly connected to the preparation box.
  • the support frame is composed of a base, a frame rod and an annular seat.
  • the external fixed sleeve of the preparation box is provided with an annular seat, and a plurality of frame rods are fixedly mounted on the annular seat.
  • the lower ends of the plurality of frame rods are commonly fixedly mounted with a base.
  • the sliding support component is composed of a slider and a slide groove.
  • a plurality of slide blocks are provided in the preparation box, and a plurality of slide grooves are fixedly installed on each of the mounting rods, and the slide grooves are slidably matched with the slide blocks of corresponding heights.
  • a fitting gasket that fits the mesh cover is fixedly mounted on one end of each mixing rod close to the mesh cover, and the end face shape of the fitting gasket is arc-shaped.
  • the transmission structure consists of a cross bar 2, an internal gear ring 1 and a gear 1.
  • Multiple cross bars 2 are fixedly installed on each of the mounting bars. Multiple cross bars 2 at the same height are commonly fixedly installed with an internal gear ring 1, and the internal gear ring 1 is meshed with multiple gears 1 at the same height at the same time.
  • a mounting plate is placed in the circular hole, an annular body is opened on the inner wall of the circular hole, a support ring matching the annular body is fixedly installed on the outside of the mounting plate, two sealing rings are fixedly installed on the outer wall of the mounting plate, and the support ring is located between the two sealing rings.
  • the upper end of the square rod is fixedly connected to the mounting plate, a circular hole is formed on the mounting plate, and the upper end of the vertical rod passes through the circular hole and is fixedly mounted with a blocking cover.
  • the linkage assembly consists of a cross bar three, a connecting seat and a vertical bar.
  • the cross bar three is fixedly installed on one side of the square bar, and the connecting seat is fixedly installed on one end of the cross bar three.
  • a square hole is opened on the connecting seat, and the vertical bar slides through the square hole.
  • the present invention has the following advantages:
  • the servo motor can drive the mixing rod and stirring plate to rotate, and drive the screen plate to move in the vertical direction, so as to better mix the materials and improve the preparation effect. At the same time, the upward movement of the screen plate can collect the floccules in the mixture.
  • the screw rod can drive the scraper rod to rotate when it rotates, and the scraper rod can move in the vertical direction with the screen plate, so as not to affect the movement of the screen plate.
  • the rotation of the mounting rod first drives the mixing rod fixedly connected thereto to rotate.
  • the rotation of the mixing rod can mix and stir the materials to a certain extent.
  • the mounting rod rotates, it drives the inner gear ring 1 to rotate through the cross bar 2.
  • the rotation of the inner gear ring 1 drives the multiple gears meshing with it to rotate.
  • the rotation of the gear 1 drives the stirring plate to rotate through the rotating shaft.
  • the rotation of the stirring plate can further improve the mixing effect of the materials.
  • FIG1 is a schematic structural diagram of a device for preparing a bioactive peptide according to the present invention.
  • FIG2 is an enlarged schematic diagram of the structure of part A in FIG1 ;
  • FIG3 is an enlarged schematic diagram of the structure of part B in FIG1 ;
  • FIG4 is an enlarged schematic diagram of the structure of portion C in FIG1 ;
  • FIG5 is an enlarged schematic diagram of the structure of portion D in FIG1 ;
  • FIG6 is a device for preparing a bioactive peptide according to the present invention.
  • FIG7 is a device for preparing a bioactive peptide according to the present invention.
  • FIG8 is a device for preparing a bioactive peptide according to the present invention.
  • a preparation device of a bioactive peptide comprises a preparation box 1 mounted on a support frame, a mesh cover 2 with two ends connected is fixedly mounted in the preparation box 1, a plurality of mounting rods 5 are mounted in the preparation box 1 through a sliding support component, a plurality of mixing rods 6 are fixedly mounted on each mounting rod 5, a mounting block 9 is fixedly mounted on the outside of the mesh cover 2 through a plurality of cross bars 8, a stirring plate 14 is mounted between corresponding two mounting blocks 9 through a rotating shaft 10, and a transmission structure is installed between the plurality of mounting rods 5 and the plurality of gears 13;
  • the support frame is composed of a base 34, a frame rod 35 and an annular seat 36.
  • the outer fixed sleeve of the preparation box 1 is provided with an annular seat 36, and a plurality of frame rods 35 are fixedly installed on the annular seat 36.
  • the lower ends of the plurality of frame rods 35 are fixedly installed with a base 34;
  • the support frame is provided to support and fix the preparation box 1 .
  • a rubber gasket with a texture may be fixedly installed on the lower surface of the base 34 .
  • the sliding support component is composed of a slider 3 and a slide groove 4.
  • a plurality of sliders 3 are provided in the preparation box 1.
  • a plurality of slide grooves 4 are fixedly installed on each mounting rod 5, and the slide grooves 4 are slidably matched with the sliders 3 of corresponding heights;
  • the end face shape of the slider 3 is shown in FIG. 2 , and the shape of the slide groove 4 matches the slider 3 .
  • the mounting rod 5 is supported in the horizontal direction and also has a certain supporting effect in the vertical direction.
  • a fitting gasket 7 is fixedly mounted on one end of each mixing rod 6 close to the mesh cover 2, and the end surface of the fitting gasket 7 is arc-shaped;
  • the arrangement of the fitting gasket 7 can make the mixing rod 6 more stable during rotation, thereby improving its stability during use.
  • the transmission structure is composed of a crossbar 11, an inner gear ring 12 and a gear 13.
  • a plurality of crossbars 11 are fixedly mounted on each mounting rod 5.
  • An inner gear ring 12 is fixedly mounted on the plurality of crossbars 11 at the same height, and the inner gear ring 12 is meshed with the plurality of gears 13 at the same height at the same time.
  • the transmission structure is set so that when the mounting rod 5 rotates, it can drive the stirring plate 14 to rotate.
  • the rotation of the stirring plate 14 can promote the circulation of materials inside and outside the mesh cover 2, thereby facilitating better preparation of bioactive peptides.
  • the preparation box 1 is provided with a feed hole (not shown in the figure), and a hole cover (not shown in the figure) is provided on the feed hole. This part is the prior art and will not be elaborated here.
  • a plurality of blocks 15 are fixedly mounted on the bottom of the mesh cover 2
  • a servo motor 16 is fixedly mounted on the lower end surface of the preparation box 1
  • a shaft 17 is fixedly mounted on the driving end of the servo motor 16
  • an internal gear ring 19 is fixedly mounted between the plurality of mounting rods 5, and a gear 18 meshing with the internal gear ring 19 is fixedly mounted on the shaft 17;
  • a motor cover can be fixedly installed on the outside of the preparation box 1.
  • the motor cover is used to isolate the servo motor 16 to improve its protection, and can also reduce the noise generated by the servo motor 16 when it is working to a certain extent.
  • the servo motor 16 can simultaneously drive multiple mounting rods 5 to rotate when working, thereby facilitating the rapid preparation of bioactive peptides.
  • the upper end of the shaft 17 is rotatably mounted on the stopper 15 located directly above it.
  • a screw rod 20 is rotatably mounted in the preparation box 1
  • a gear 3 21 meshing with the gear 2 18 is fixedly mounted on the screw rod 20
  • a mesh plate 23 is mounted on the screw rod 20 through a ball nut 22;
  • the gear 3 21 cooperates with the gear 2 18 so that the shaft 17 rotates and the screw rod 20 also rotates.
  • the screw rod 20 rotates by the operation of the servo motor 16.
  • the ball nut 22 cooperates with the mesh plate 23 to move in the vertical direction as the screw 20 rotates.
  • the vertical movement of the mesh plate 23 can move the flocculent precipitate generated during the preparation process from the bottom to the top.
  • a square rod 24 is fixedly mounted on the upper end of the screw rod 20, a circular hole is opened on the upper end of the preparation box 1, a vertical rod 27 is installed on the square rod 24 through a linkage assembly, a scraper rod 28 is fixedly mounted on the lower end of the vertical rod 27, and a discharge pipe 33 with a valve is fixedly connected to the preparation box 1;
  • a mounting plate 30 is placed in the circular hole, an annular body is provided on the inner wall of the circular hole, a support ring 29 matching the annular body is fixedly installed on the outside of the mounting plate 30, two sealing rings are fixedly installed on the outer wall of the mounting plate 30, and the support ring 29 is located between the two sealing rings;
  • the sealing ring is provided to improve the sealing effect of the circular hole and prevent dust and other foreign matter from entering the preparation box 1 through the connection.
  • the upper end of the square rod 24 is fixedly connected to the mounting plate 30.
  • the mounting plate 30 is provided with a circular hole 32.
  • the upper end of the vertical rod 27 passes through the circular hole 32 and is fixedly installed with a blocking cover 31;
  • the purpose of providing the blocking cover 31 is to limit the movement range of the vertical rod 27 (to the lowest movement position).
  • the linkage assembly consists of a cross bar 3 25, a connecting seat 26 and a vertical bar 27.
  • the cross bar 3 25 is fixedly installed on one side of the square bar 24, and the connecting seat 26 is fixedly installed on one end of the cross bar 3 25.
  • a square hole is opened on the connecting seat 26, and the vertical bar 27 slides through the square hole.
  • the servo motor 16 when the bioactive peptide is prepared, the servo motor 16 is turned on, and the servo motor 16 drives the gear 2 18 to rotate through the shaft 17, and the gear 2 18 rotates through the inner gear ring 2 19 to drive the multiple mounting rods 5 to rotate at the same time, and the gear 2 18 rotates through the gear 3 21 to also drive the screw 20 to rotate;
  • the rotation of the mounting rod 5 first drives the mixing rod 6 fixedly connected thereto to rotate, and the rotation of the mixing rod 6 can mix and stir the materials to a certain extent.
  • the mounting rod 5 rotates, it drives the inner gear ring 12 to rotate through the cross bar 2 11, and the inner gear ring 12 drives the multiple gears 13 meshing therewith to rotate.
  • the rotation of the gear 13 drives the stirring plate 14 to rotate through the rotating shaft 10, and the rotation of the stirring plate 14 can further improve the mixing effect of the materials.
  • the screw rod 20 rotates through the ball nut 22 to drive the mesh plate 23 to move in the vertical direction (the servo motor 16 is used to control the square rotation of the shaft 17 to realize the up and down reciprocating movement of the mesh plate 23 in the vertical direction).
  • the movement of the mesh plate 23 in the vertical direction can firstly further improve the mixing effect of the material, and at the same time can also collect the flocculent sediment in the material upward, so as to facilitate the cleaning of the flocculent after the mixing is completed in the later stage;
  • the screw rod 20 rotates to drive the square rod 24 fixedly connected thereto to rotate, and the square rod 24 rotates through the three cross bars. 25.
  • the connecting seat 26 drives the vertical rod 27 to rotate in the horizontal direction.
  • the rotation of the vertical rod 27 drives the scraper rod 28 to rotate on the upper surface of the mesh plate 23, so as to facilitate better mixing of the materials and also facilitate the collection of flocs.

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

一种生物活性肽的制备装置，包括安装在支撑架体上的制备箱（1），制备箱（1）内固定安装有两端连通的网罩（2），制备箱（1）内通过滑动支撑部件安装有多个安装杆（5），每个安装杆（5）上均固定安装有多个混合杆（6），网罩（2）的外部均通过多个横杆一（8）固定安装有一个安装块（9），相应两安装块（9）之间通过转轴（10）安装有一个搅拌板（14），多个安装杆（5）与多个齿轮一（13）之间安装有传动结构；网罩（2）的底部固定安装有多个挡块（15），制备箱（1）的下端面固定安装有伺服电机（16），伺服电机（16）的驱动端固定安装有轴体（17），多个安装杆（5）之间共同固定安装有一个内齿环二（19），轴体（17）上固定安装有与内齿环二（19）相啮合的齿轮二（18）；制备箱（1）内转动安装有丝杆（20），丝杆（20）上固定安装有与齿轮二（18）相啮合的齿轮三（21），丝杆（20）上通过滚珠螺母（22）安装有网板（23）；丝杆（20）的上端固定安装有方形杆（24），制备箱（1）的上端开设有圆形孔洞，方形杆（24）通过连动组件安装有竖杆（27），竖杆（27）的下端固定安装有刮杆（28），制备箱（1）上固定连通有具有阀门的出料管（33）。

Description

一种生物活性肽的制备装置 技术领域
本发明涉及活性肽制备技术领域，尤其涉及一种生物活性肽的制备装置。
背景技术
经检索，专利号为CN216445271U的中国授权实用新型专利文件公开了生物活性肽的制备装置，包括底板，所述底板的顶部设置有釜体，所述釜体的顶部设置有盖体，所述釜体上设置有升降机构，所述釜体的底端设置有搅拌机构；
该专利的说明书部分记载有：通过第二正方电机带动搅拌叶转动的同时，第三正反电机通过螺纹轴杆带动承载架随搅拌页转动的同时在竖直方向上进行上下移动，避免第一过滤网静态过滤时造成的堵塞；
由上述记载，可知该制备装置在使用过程中还存在以下不足之处：第一过滤机构的转动时利用搅拌叶的转动来实现的，但搅拌叶相对釜体的宽度较小，其与第一过滤机构所接触的宽度也较小，从而并不能很好的满足使用所需(转动的同时还能在竖直方向上上下移动)。
发明内容
本发明的目的是为了解决背景技术中所提出的问题，而提出的一种生物活性肽的制备装置。
为了实现上述目的，本发明采用了如下技术方案：
一种生物活性肽的制备装置，包括安装在支撑架体上的制备箱，所述制备箱内固定安装有两端连通的网罩，所述制备箱内通过滑动支撑部件安装有多个安装杆，每个所述安装杆上均固定安装有多个混合杆，所述网罩的外部均通过多个横杆一固定安装有一个安装块，相应两所述安装块之间通过转轴安装有一个搅拌板，多个所述安装杆与多个所述齿轮一之间安装有传动结构；
所述网罩的底部固定安装有多个挡块，所述制备箱的下端面固定安装有伺服电机，所述伺服电机的驱动端固定安装有轴体，多个所述安装杆之间共同固定安装有一个内齿环二，所述轴体上固定安装有与内齿环二相啮合的齿轮二；
所述制备箱内转动安装有丝杆，所述丝杆上固定安装有与齿轮二相啮合的齿轮三，所述丝杆上通过滚珠螺母安装有网板；
所述丝杆的上端固定安装有方形杆，所述制备箱的上端开设有圆形孔洞，所述方形杆通过连动组件安装有竖杆，所述竖杆的下端固定安装有刮杆，所述制备箱上固定连通有具有阀门的出料管。
在上述的一种生物活性肽的制备装置中，所述支撑架体由底座、架杆以及环形座组成，所述制备箱的外部固定套设有环形座，所述环形座上固定安装有多个架杆，多个所述架杆的下端共同固定安装有一个底座。
在上述的一种生物活性肽的制备装置中，所述滑动支撑部件由滑块、滑槽组成，所 述制备箱内开设有多个滑块，每个所述安装杆上均固定安装有多个滑槽，且滑槽与相应高度的滑块滑动配合。
在上述的一种生物活性肽的制备装置中，每个所述混合杆靠近网罩的一端均固定安装有与网罩贴合的贴合垫片，且贴合垫片的端面形状为弧形。
在上述的一种生物活性肽的制备装置中，所述传动结构由横杆二、内齿环一以及齿轮一组成，每个所述安装杆上均固定安装有多个横杆二，处于同一高度的多个所述横杆二共同固定安装有一个内齿环一，且内齿环一与同一高度的多个齿轮一同时相啮合。
在上述的一种生物活性肽的制备装置中，所述圆形孔洞内放置有安装盘，所述圆形孔洞的内壁上开设有环形体，所述安装盘的外部固定安装有与环形体相配合的支撑环，所述安装盘的外壁上固定安装有两密封圈，且支撑环位于两密封圈之间。
在上述的一种生物活性肽的制备装置中，所述方形杆的上端与安装盘固定连接，所述安装盘上开设有圆形孔，所述竖杆的上端穿过圆形孔并固定安装有挡盖。
在上述的一种生物活性肽的制备装置中，所述连动组件由横杆三、连接座以及竖杆组成，所述方形杆的一侧固定安装有横杆三，所述横杆三的一端固定安装有连接座，所述连接座上开设有方形孔，且竖杆滑动贯穿该方形孔。
与现有的技术相比，本发明优点在于：
1：利用伺服电机的工作可带动混合杆、搅拌板转动，带动网板在竖直方向上移动，从而可更好的对物料进行混合，提高其制备效果，同时利用网板向上的移动，可将混合物中的絮状物进行收集。
2：通过方形杆、横杆三、连接座、竖杆的配合使用，使得丝杆在发生转动时可带动刮杆一起转动，且刮杆可随网板在竖直方向上移动，从而不会对网板的移动产生影响。
3：安装杆转动首先带动与之固定连接的混合杆进行转动，混合杆转动可在一定程度上对物料进行混合搅拌，同时安装杆在转动时通过横杆二带动内齿环一进行转动，内齿环一转成带动与之啮合的多个齿轮一进行转动，齿轮一转动通过转轴带动搅拌板转动，搅拌板转动可进一步提高对物料的混合效果。
附图说明
图1为本发明提出的一种生物活性肽的制备装置的结构示意图；
图2为图1中A部分的结构放大示意图；
图3为图1中B部分的结构放大示意图；
图4为图1中C部分的结构放大示意图；
图5为图1中D部分的结构放大示意图；
图6为本发明提出的一种生物活性肽的制备装置中；
图7为本发明提出的一种生物活性肽的制备装置中；
图8为本发明提出的一种生物活性肽的制备装置中。
图中：1制备箱、2网罩、3滑块、4滑槽、5安装杆、6混合杆、7贴合垫片、8横杆一、9安装块、10转轴、11横杆二、12内齿环一、13齿轮一、14搅拌板、15挡块、16伺服电机、17轴体、18齿轮二、19内齿环二、20丝杆、21齿轮三、22滚珠螺母、23网板、24方形杆、25横杆三、26连接座、27竖杆、28刮杆、29支撑环、30安装盘、31挡盖、32圆形孔、33出料管、34底座、35架杆、36 环形座。
具体实施方式
下面将结合本发明实施例中的附图，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
参照图1-3，一种生物活性肽的制备装置，包括安装在支撑架体上的制备箱1，制备箱1内固定安装有两端连通的网罩2，制备箱1内通过滑动支撑部件安装有多个安装杆5，每个安装杆5上均固定安装有多个混合杆6，网罩2的外部均通过多个横杆一8固定安装有一个安装块9，相应两安装块9之间通过转轴10安装有一个搅拌板14，多个安装杆5与多个齿轮一13之间安装有传动结构；
上述值得注意的有以下几点：
1、支撑架体由底座34、架杆35以及环形座36组成，制备箱1的外部固定套设有环形座36，环形座36上固定安装有多个架杆35，多个架杆35的下端共同固定安装有一个底座34；
支撑架体的设置对制备箱1起到支撑固定作用，同时为提高其放置时的稳定性，可在底座34的下表面固定安装一个具有纹理的橡胶垫片。
2、滑动支撑部件由滑块3、滑槽4组成，制备箱1内开设有多个滑块3，每个安装杆5上均固定安装有多个滑槽4，且滑槽4与相应高度的滑块3滑动配合；
滑块3的端面形状如图2所示，滑槽4的形状与滑块3相配合，利用二者该形状的配合，使得安装杆5在受到水平方向支撑的同时，在竖直方向上也具有一定的支撑效果。
3、每个混合杆6靠近网罩2的一端均固定安装有与网罩2贴合的贴合垫片7，且贴合垫片7的端面形状为弧形；
贴合垫片7的设置，可使得混合杆6在转动过程中更加的平稳，提高其使用时的稳定性。
4、传动结构由横杆二11、内齿环一12以及齿轮一13组成，每个安装杆5上均固定安装有多个横杆二11，处于同一高度的多个横杆二11共同固定安装有一个内齿环一12，且内齿环一12与同一高度的多个齿轮一13同时相啮合；
传动结构的设置，使得安装杆5在发生转动时，可带动搅拌板14进行转动，利用搅拌板14的转动可促使物料在网罩2内外进行循环流动，从而便于更好的进行生物活性肽的制备。
5、制备箱1上具有进料孔(图中未示出)，进料孔上卡合设置有孔盖(图中未示出)，该部分为现有技术，在此不做阐述。
参照图1、图4、图6以及图7，网罩2的底部固定安装有多个挡块15，制备箱1的下端面固定安装有伺服电机16，伺服电机16的驱动端固定安装有轴体17，多个安装杆5之间共同固定安装有一个内齿环二19，轴体17上固定安装有与内齿环二19相啮合的齿轮二18；
上述值得注意的有以下几点：
1、可在制备箱1的外部固定安装一个电机罩，电机罩用于对伺服电机16进行隔离，提高对其的保护，同时也能对伺服电机16工作时产生的噪音进行一定程度的削减。
2、通过齿轮二18与内齿环二19的配合使用，使得伺服电机16工作时可同时带动多个安装杆5进行转动，从而便于快速进行生物活性肽的制备。
3、轴体17的上端转动安装在位于其正上方的挡块15上。
参照图1、图4以及图7，制备箱1内转动安装有丝杆20，丝杆20上固定安装有与齿轮二18相啮合的齿轮三21，丝杆20上通过滚珠螺母22安装有网板23；
上述值得注意的有以下两点：
1、通过齿轮三21与齿轮二18的配合使得轴体17转动时也会带动丝杆20发生转动，利用伺服电机16的工作可使得丝杆20发生转动。
2、通过滚珠螺母22的配合使得网板23随丝杆20的转动可在竖直方向上发生移动，利用网板23在竖直方向上的移动，可将制备过程中产生的絮状物沉淀从底部移动至上方。
参照图1、图4、图5以及图8，丝杆20的上端固定安装有方形杆24，制备箱1的上端开设有圆形孔洞，方形杆24通过连动组件安装有竖杆27，竖杆27的下端固定安装有刮杆28，制备箱1上固定连通有具有阀门的出料管33；
上述值得注意的有以下几点：
1、圆形孔洞内放置有安装盘30，圆形孔洞的内壁上开设有环形体，安装盘30的外部固定安装有与环形体相配合的支撑环29，安装盘30的外壁上固定安装有两密封圈，且支撑环29位于两密封圈之间；
设置密封圈的设置用于提高对圆形孔洞的密封效果，避免灰尘等外界杂物通过连接处进入到制备箱1内。
2、方形杆24的上端与安装盘30固定连接，安装盘30上开设有圆形孔32，竖杆27的上端穿过圆形孔32并固定安装有挡盖31；
设置挡盖31的目的对竖杆27的移动幅度进行了限制(最低移动位置)。
3、连动组件由横杆三25、连接座26以及竖杆27组成，方形杆24的一侧固定安装有横杆三25，横杆三25的一端固定安装有连接座26，连接座26上开设有方形孔，且竖杆27滑动贯穿该方形孔。
进一步说明，上述固定连接，除非另有明确的规定和限定，否则应做广义理解，例如，可以是焊接，也可以是胶合，或者一体成型设置等本领域技术人员熟知的惯用手段。
本发明中，当进行生物活性肽的制备时，开启伺服电机16，伺服电机16工作通过轴体17带动齿轮二18进行转动，齿轮二18转动通过内齿环二19带动多个安装杆5同时进行转动，齿轮二18转动通过齿轮三21也带动丝杆20进行转动；
安装杆5转动首先带动与之固定连接的混合杆6进行转动，混合杆6转动可在一定程度上对物料进行混合搅拌，同时安装杆5在转动时通过横杆二11带动内齿环一12进行转动，内齿环一12转成带动与之啮合的多个齿轮一13进行转动，齿轮一13转动通过转轴10带动搅拌板14转动，搅拌板14转动可进一步提高对物料的混合效果；
丝杆20转动通过滚珠螺母22带动网板23在竖直方向上进行移动(利用伺服电机16控制轴体17的正方转，可实现网板23在竖直方向上的上下往复移动)，网板23在竖直方向上的移动首先可进一步提高对物料的混合效果，同时还可对物料中的絮状沉淀物起到向上收集效果，便于在后期混合结束后对絮状物进行清理；
丝杆20转动带动与之固定连接的方形杆24进行转动，方形杆24转动通过横杆三 25、连接座26带动竖杆27水平方向上进行转动，竖杆27转动带动刮杆28在网板23的上表面上进行转动，从而便于更好的对物料进行混合，同时也便于对絮状物的收集。
以上所述，仅为本发明较佳的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其发明构思加以等同替换或改变，都应涵盖在本发明的保护范围之内。

Claims (8)

  1. 一种生物活性肽的制备装置，包括安装在支撑架体上的制备箱(1)，其特征在于，所述制备箱(1)内固定安装有两端连通的网罩(2)，所述制备箱(1)内通过滑动支撑部件安装有多个安装杆(5)，每个所述安装杆(5)上均固定安装有多个混合杆(6)，所述网罩(2)的外部均通过多个横杆一(8)固定安装有一个安装块(9)，相应两所述安装块(9)之间通过转轴(10)安装有一个搅拌板(14)，多个所述安装杆(5)与多个所述齿轮一(13)之间安装有传动结构；
    所述网罩(2)的底部固定安装有多个挡块(15)，所述制备箱(1)的下端面固定安装有伺服电机(16)，所述伺服电机(16)的驱动端固定安装有轴体(17)，多个所述安装杆(5)之间共同固定安装有一个内齿环二(19)，所述轴体(17)上固定安装有与内齿环二(19)相啮合的齿轮二(18)；
    所述制备箱(1)内转动安装有丝杆(20)，所述丝杆(20)上固定安装有与齿轮二(18)相啮合的齿轮三(21)，所述丝杆(20)上通过滚珠螺母(22)安装有网板(23)；
    所述丝杆(20)的上端固定安装有方形杆(24)，所述制备箱(1)的上端开设有圆形孔洞，所述方形杆(24)通过连动组件安装有竖杆(27)，所述竖杆(27)的下端固定安装有刮杆(28)，所述制备箱(1)上固定连通有具有阀门的出料管(33)。
  2. 根据权利要求1所述的一种生物活性肽的制备装置，其特征在于，所述支撑架体由底座(34)、架杆(35)以及环形座(36)组成，所述制备箱(1)的外部固定套设有环形座(36)，所述环形座(36)上固定安装有多个架杆(35)，多个所述架杆(35)的下端共同固定安装有一个底座(34)。
  3. 根据权利要求1所述的一种生物活性肽的制备装置，其特征在于，所述滑动支撑部件由滑块(3)、滑槽(4)组成，所述制备箱(1)内开设有多个滑块(3)，每个所述安装杆(5)上均固定安装有多个滑槽(4)，且滑槽(4)与相应高度的滑块(3)滑动配合。
  4. 根据权利要求1所述的一种生物活性肽的制备装置，其特征在于，每个所述混合杆(6)靠近网罩(2)的一端均固定安装有与网罩(2)贴合的贴合垫片(7)，且贴合垫片(7)的端面形状为弧形。
  5. 根据权利要求1所述的一种生物活性肽的制备装置，其特征在于，所述传动结构由横杆二(11)、内齿环一(12)以及齿轮一(13)组成，每个所述安装杆(5)上均固定安装有多个横杆二(11)，处于同一高度的多个所述横杆二(11)共同固定安装有一个内齿环一(12)，且内齿环一(12)与同一高度的多个齿轮一(13)同时相啮合。
  6. 根据权利要求1所述的一种生物活性肽的制备装置，其特征在于，所述圆形孔洞内放置有安装盘(30)，所述圆形孔洞的内壁上开设有环形体，所述安装盘(30)的外部固定安装有与环形体相配合的支撑环(29)，所述安装盘(30)的外壁上固定安装有两密封圈，且支撑环(29)位于两密封圈之间。
  7. 根据权利要求6所述的一种生物活性肽的制备装置，其特征在于，所述方形杆(24)的上端与安装盘(30)固定连接，所述安装盘(30)上开设有圆形孔(32)，所述竖杆(27)的上端穿过圆形孔(32)并固定安装有挡盖(31)。
  8. 根据权利要求7所述的一种生物活性肽的制备装置，其特征在于，所述连动组件由横杆三(25)、连接座(26)以及竖杆(27)组成，所述方形杆(24)的一侧固定安装有横杆三(25)，所述横杆三(25)的一端固定安装有连接座(26)，所述连接座(26)上开设有方形孔，且竖杆 (27)滑动贯穿该方形孔。
PCT/CN2023/092480 2022-10-18 2023-05-06 一种生物活性肽的制备装置 WO2024082609A1 (zh)

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