WO2024042118A1 - Device and process for the manufacture of hollow fiber membrane bundles - Google Patents
Device and process for the manufacture of hollow fiber membrane bundles Download PDFInfo
- Publication number
- WO2024042118A1 WO2024042118A1 PCT/EP2023/073113 EP2023073113W WO2024042118A1 WO 2024042118 A1 WO2024042118 A1 WO 2024042118A1 EP 2023073113 W EP2023073113 W EP 2023073113W WO 2024042118 A1 WO2024042118 A1 WO 2024042118A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hollow fiber
- lid
- fiber membranes
- base
- winding wheel
- Prior art date
Links
- 239000012510 hollow fiber Substances 0.000 title claims abstract description 66
- 239000012528 membrane Substances 0.000 title claims abstract description 58
- 238000000034 method Methods 0.000 title claims abstract description 19
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 15
- 238000004804 winding Methods 0.000 claims description 33
- 230000000737 periodic effect Effects 0.000 claims description 19
- 239000011800 void material Substances 0.000 claims description 13
- 238000005520 cutting process Methods 0.000 claims description 4
- 238000001914 filtration Methods 0.000 abstract description 2
- 238000009792 diffusion process Methods 0.000 abstract 1
- 239000000835 fiber Substances 0.000 description 13
- 239000000463 material Substances 0.000 description 11
- 230000007547 defect Effects 0.000 description 6
- 239000011888 foil Substances 0.000 description 2
- 239000002390 adhesive tape Substances 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 229920006254 polymer film Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/021—Manufacturing thereof
- B01D63/0233—Manufacturing thereof forming the bundle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/021—Manufacturing thereof
- B01D63/0231—Manufacturing thereof using supporting structures, e.g. filaments for weaving mats
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2323/00—Details relating to membrane preparation
- B01D2323/42—Details of membrane preparation apparatus
Definitions
- the present disclosure relates to devices and processes for the production of hollow fiber membrane bundles .
- the bundles are used for the manufacture of filtration and/or di f fusion devices , e . g . , capillary dialyzers .
- US 4 276 687 A discloses a process for the production of hollow fiber bundles which involves winding the fibers onto a reel member to form an annular assembly of the fibers and thereafter cutting the annular assembly into separate bundles . Individual bundles are wrapped in a flexible sheet and cut at their ends .
- US 6 951 611 A discloses a method for manufacturing a hollow fiber membrane module which involves filter housings having first and second portions flexibly connected to each other .
- the filter housings are mounted on a winding wheel ; hollow fibers are continuously fed to the first portions of the filter housings as the wheel is rotated; and subsequently the first and second portions of the filter housing are j oined .
- WO 2016/ 102364 Al discloses an apparatus for winding a foil around a strand of hollow f iber membranes having an irregular cross-section and for forming the strand to circular bundles .
- the device comprises at least four form segments which can be moved towards the center of a circle individually .
- the contours of their profiles form a closed line of approximately circular shape when the segments are moved .
- the segments are wide open, and a sheet of wrapping film and a strand of fibers are inserted into the device .
- the film is bent by pivoting movements of the segments to such an extent that it partially encloses the strand of fibers , with one of the film edges initially being folded over more than the opposite side .
- the two inner mold segments move upwards approximately simultaneously to form an approximately semi-circular trough supporting the strand, and then the outer mold segments move sequentially onto the strand, thereby overlapping the edges of the fi lm over each other and enclosing the strand .
- the strand After the strand has been compressed to the desired diameter, it is fixed by welding together the overlapping areas of the film or fixing them with adhesive tape .
- EP 2 420 464 Al also discloses a device for wrapping a fiber bundle with a film, with a receptacle consisting of a first and a second side element and a flexible channel fastened between them, for picking up the film and the fiber bundle , with a drive being provided in order to move at least the first side element transversely to the chute , and at least one folder movable transversely to the chute for folding the film around the fiber bundle .
- US 2021 / 106949 Al discloses an apparatus for preparing bundles of hollow fiber membranes wrapped in a wrapping material , e . g . , polymer film, paper, or aluminum foil .
- a winding wheel equipped with a plurality of devices for wrapping a bundle of hollow fiber membranes is provided .
- Each device comprises a base featuring a trough in the shape of a cylinder section; and on each longitudinal side of the trough, a rigid flap with an inner surface forming a cylinder section, each of the two flaps being connected to the base via a hinge , the hinges being located on the longitudinal brims of the trough, so that each of the two flaps is moveable between a first position and a second position .
- the device is configured to receive a sheet of wrapping material and a plurality of fibers when both flaps are in the first position, and the trough and the two flaps together frame a cylindrical void when both f laps are in the second position .
- a process for preparing a plurality of bundles of hollow fiber membranes , each bundle being enveloped in a sheet of wrapping material comprises moving both flaps of each of the devices of the winding wheel into the first position; introducing a sheet of wrapping material into each of the devices ; introducing a plurality of hollow fiber membranes into each of the devices by winding a strand of hollow fiber membranes onto the winding wheel into the troughs of the devices , so that the hollow fiber membranes are located atop the sheets of wrapping material ; forming a cylindrical bundle of hollow fiber membranes and enveloping it with the wrapping material by successively moving the flaps of each device into the second position; and sealing the longitudinal edge of the sheets of wrapping material .
- US 4 224 094 A discloses a method and apparatus for the simultaneous preparation of several hollow fiber devices , wherein at least one hollow fiber is wound around means , at least three in number, located in di f ferent planes thereby obtaining with this fiber an envelope having a polygonal section, which can be cut in at least two places as it is formed, to obtain at least two distinct groups of hollow fiber lengths .
- the present disclosure provides devices and processes for the production of bundles of hollow fiber membranes .
- the device of the present disclosure is configured to hold a bundle of hollow fiber membranes and comprises a base and a lid connected to the base via hinges . Both the base and the lid feature a trough in the shape of a cylinder section .
- the cylinder sections of the base and the lid together form a full cylinder when the device is in a closed configuration . Where base and lid contact each other in the closed configuration of the device , both the base and the lid feature longitudinal edges having the form of a periodic curve oscillating around a mean value instead of straight longitudinal edges .
- Figure 1 shows perspective views of a prior art device for producing bundles of hollow fiber membranes : a ) open configuration, b ) closed configuration;
- Figure 2 shows perspective views of an embodiment of the device of the present disclosure : a ) open configuration, b ) closed configuration;
- Figure 3 shows a side view of an embodiment of the device of the present disclosure in closed configuration
- Figure 4 shows cross-sectional views of the device of Figure 3 : a ) along line A-A, b ) along line N-N .
- the present disclosure provides a device for the production of a bundle of hollow fiber membranes .
- One embodiment is a device configured to receive and hold a bundle of hollow fiber membranes .
- the device comprises a base and a rigid lid connected to the base via hinges .
- the lid can be rotated around the respective hinge , to move the lid between a first position corresponding to an open configuration of the device , and a second position corresponding to a closed configuration of the device .
- Both the base and the lid feature a trough in the shape of a cylinder section .
- the cylinder sections of the base and the lid together form a full cylinder when the device is in a closed configuration .
- the inner surfaces of the device that is , the inner surfaces of the troughs of the base and the lid are positioned on the surface area of a cylindrical void .
- the inner surface of the device completely covers the surface of the cyl indrical void, i . e . , the inner surface of the device forms a cylinder . No gap is present in the surface that would allow for individual hollow fibers to pass through it .
- the lid of the device is opened prior to introducing the hollow fibers into the device , and closed after the desired number of hollow fiber membranes has been collected .
- the contours of the edges of base and lid contacting each other take a particular form in the device of the present disclosure .
- both the base and the lid feature longitudinal edges having the form of a periodic curve oscillating around a mean value instead of straight longitudinal edges .
- the base and the lid together form a tight seal over the entire length of the device .
- the periodic curve corresponds to a cosine curve , A* cos (x ) , having maxima at both ends of the device .
- the periodic curve corre- spends to an inverted cosine curve, A* (-cos (x) ) , having minima at both ends of the device.
- the periodic curve corresponds to a sine curve, A*sin(x) , the amplitude of the curve corresponding to the mean value at both ends of the device.
- the periodic curve is comprised of consecutive circular or ellipsoidal segments in alternating orientation.
- a central angle of each of the segments is equal to or less than 180°, for instance, from 60° to 90°, e.g., from 70 to 80°.
- the periodic curve is comprised of a sequence of circular segments in alternating orientation and with identical radius, the radius being in the range of from 10 mm to 30 mm, e.g., from 15 to 20 mm.
- the length of the device corresponds to an integer number of periods of the periodic function.
- the integer is in the range of from 2 to 12, for instance, from 4 to 8.
- the amplitude of the periodic function, measured from the line representing the mean value is in the range of from 4 mm to 20 mm, e.g., from 5 mm to 15 mm.
- the contributions of the lid and the base to the cylinder vary over the length of the cylinder, oscillating between two limit values.
- the contributions of the lid and the base on average correspond to 180° of the full circle.
- the trough of the lid constitutes a smaller fraction of the full cylinder than the trough of the base.
- the average contribution of the lid corresponds to 90° to 160° of the full circle (360°)
- the average contribution of the base corresponds to from 200° to 270° of the full circle.
- the average contribution of the lid corresponds to from 120° to 150° of the full circle
- the average contribution of the base corresponds to from 210° to 270° of the full circle.
- the contribution of the lid varies between 100° and 150° of the full circle over the length of the cylinder
- the contribution of the base varies between and between 210° and 260° of the full circle over the length of the cylinder.
- the inner surface of the device forms a cylinder.
- the diameter of the cylinder is in the range of from 30 mm to 50 mm, for instance, from 35 to 45 mm.
- the inner diameter is in the range of from 35 mm to 38 mm.
- the diameter of the cylinder is in the range of from 15 mm to 25 mm, for instance, from 17 to 20 mm.
- the present disclosure also provides a winding wheel equipped with a plurality of devices as described above.
- the winding wheel is equipped with 4 to 30 devices.
- the winding wheel additionally comprises means for moving the lid of the devices back and forth between the first position and the second position, i.e., changing the configuration of the devices between the open and the closed configuration, and between the closed and the open configuration.
- the winding wheel allows for the simultaneous production of multiple bundles of hollow fiber membranes.
- the present disclosure also provides a process for preparing a bundle of hollow fiber membranes .
- the process involves providing a device of the present disclosure in an open configuration, collecting a plurality of hollow fiber membranes in the trough of the device to produce a bundle of hollow fiber membranes , subsequently closing the lid of the device to confine the bundle of hollow fiber membranes in the cylindrical void of the device , and subsequently cutting the bundle of hollow fiber membranes at both ends of the device to obtain a bundle of hollow fiber membranes having a defined length .
- One embodiment of the process employs a plurality of devices of the present disclosure .
- the devices are mounted on a winding wheel to simultaneously produce a plurality of bundles of hollow fiber membranes .
- a plurality of hollow fiber membranes is introduced into each of the plurality of devices by winding a strand of hollow fiber membranes onto the winding wheel into the troughs of the devices . Again, no additional wrapping material is present in the troughs of the plurality of de- vices when the strand of fibers is wound onto the winding wheel .
- the process involves feeding a strand of hollow fiber membranes to a winding wheel and collecting the strand of hollow fiber membranes in devices of the present disclosure in their open configuration arranged on the outer circumference of the winding wheel by turning the wheel .
- the winding wheel is stopped, the devices are closed around the strand of hollow fiber membranes and subsequently the hollow fiber membranes are cut between the devices .
- the devices are removed from the winding wheel and the bundles of hollow fiber membranes are trans ferred into tubular filter casings .
- the devices feature means that facilitate opening and closing of the lid, e . g . , handles , knobs , or rollers attached to the lid .
- the devices are opened and closed as required, e . g . , using a robot .
- a winding wheel having a plurality of devices mounted thereon is equipped with means which mechanically close or open, as required for the respective process step, the lids of the individual devices as the winding wheel rotates .
- Figure 1 shows two perspective views of a prior art device 20 for producing bundles of hollow fiber membranes .
- Drawing a shows the device 20 in open configuration, drawing b ) in closed configuration ( rotated by 180 ° around the z axis ) .
- the device 20 comprises an elongated base 21 featuring a trough having the shape of a cylinder section .
- a lid 22 is located on one longitudinal side of the base 21 .
- the trough of base 21 and the inner surface of the lid 22 together frame a cylindrical void when the device 20 is in closed configuration .
- the diameter of cylindrical void of the device 20 is 37 mm .
- Figure 2 shows two perspective views of an embodiment of the device 1 of the present disclosure .
- Drawing a shows the device 1 in open configuration, drawing b ) in closed configuration ( rotated by 180 ° around the z axis ) .
- the device 1 comprises an elongated base 2 featuring a trough having the shape of a cylinder section .
- On one longitudinal side of the base 2 a lid 3 is located .
- the inner surface of the lid 3 forms a cylinder section .
- the lid 3 is connected to the base 2 via hinges 4 , so that the lid 3 is moveable between a first position ( corresponding to the open configuration) , shown in drawing a ) and a second position ( corresponding to the closed configuration) shown in drawing b ) .
- a plurality of fibers can be introduced into the device when the lid 3 is in the first position .
- the trough of base 2 and the inner surface of the lid 3 together frame a cylindrical void 7 .
- the longitudinal edges 5 of the base 2 and the longitudinal edges 6 of the lid 3 are shaped in the form of a periodic curve oscillating around a mean value .
- the shapes of the longitudinal edges 5 and 6 correspond to each other, so that the base 2 and the lid 3 form a tight fit when the device
- the device 1 is in closed configuration .
- the device 1 also features a handle 8 for opening and closing the device 1 .
- Figure 3 shows a side view of an embodiment of the device 1 of the present disclosure in closed configuration .
- L is the overall length of thew device .
- the wavelength of the periodic curve formed by longitudinal edges 5 and 6 , respectively, is L/ 6 , i . e . , the length of the edges 5 and 6 , respectively, correspond to six full periods of the curve .
- the length L of the device is 265 mm
- the periodic curve is comprised of a sequence of circular segments having a radius of 18 mm each .
- the curve has maxima at both ends of the device 1 . In other embodiments of the device 1 , the curve has minima at both ends of the device 1 .
- Figure 4 shows cross-sectional views of the device 1 of Figure 3 : a ) along line A-A, b ) along line N-N .
- the as- sembly plate 9 is attached to base 2 with bolts 10, the handle 8 is fixed to the lid 3 with bolt 11.
- hollow fiber membrane bundles comprising 12024 hollow fibers each were produced and subsequently transferred into dialyzer housings. The hollow fiber membrane bundles then were inspected for flaws like loops, kinks, fractures, etc.
- hollow fiber membrane bundles comprising 12024 hollow fibers each were produced and subsequently transferred into dialyzer housings. The bundles then were inspected for defects like loops, kinks, fractures, etc. 117 dialyzers were analyzed . In total , 140 defects were observed, corresponding to an average of 1 . 20 defects per bundle .
- the number of defects present in the bundles is reduced by about one third, as compared to bundles produced using the prior art device .
Landscapes
- Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP22192089.5A EP4327918A1 (de) | 2022-08-25 | 2022-08-25 | Vorrichtung und verfahren zur herstellung von hohlfasermembranbündeln |
EP22192089.5 | 2022-08-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2024042118A1 true WO2024042118A1 (en) | 2024-02-29 |
Family
ID=83081764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2023/073113 WO2024042118A1 (en) | 2022-08-25 | 2023-08-23 | Device and process for the manufacture of hollow fiber membrane bundles |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP4327918A1 (de) |
WO (1) | WO2024042118A1 (de) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4224094A (en) | 1976-05-10 | 1980-09-23 | Rhone-Poulenc Industries | Method and apparatus for simultaneous production of plural hollow fiber devices by winding |
US4276687A (en) | 1979-05-21 | 1981-07-07 | Baxter Travenol Laboratories, Inc. | Method of winding capillary fiber bundles |
US6951611B2 (en) | 1999-01-29 | 2005-10-04 | Gambro Dialysatoren Gmbh & Co. Kg | Filters and method for producing filters |
EP2420464A1 (de) | 2006-12-04 | 2012-02-22 | Fresenius Medical Care Deutschland GmbH | Vorrichtungen und Verfahren zur Herstellung von Faserbündeln |
WO2016102364A1 (de) | 2014-12-23 | 2016-06-30 | Hermann Reuschenbach | Vorrichtung und verfahren zur herstellung von fadenbündeln |
US20210106949A1 (en) | 2017-03-29 | 2021-04-15 | Gambro Lundia Ab | Device and process for the manufacture of hollow fiber membrane bundles |
-
2022
- 2022-08-25 EP EP22192089.5A patent/EP4327918A1/de active Pending
-
2023
- 2023-08-23 WO PCT/EP2023/073113 patent/WO2024042118A1/en unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4224094A (en) | 1976-05-10 | 1980-09-23 | Rhone-Poulenc Industries | Method and apparatus for simultaneous production of plural hollow fiber devices by winding |
US4276687A (en) | 1979-05-21 | 1981-07-07 | Baxter Travenol Laboratories, Inc. | Method of winding capillary fiber bundles |
US6951611B2 (en) | 1999-01-29 | 2005-10-04 | Gambro Dialysatoren Gmbh & Co. Kg | Filters and method for producing filters |
EP2420464A1 (de) | 2006-12-04 | 2012-02-22 | Fresenius Medical Care Deutschland GmbH | Vorrichtungen und Verfahren zur Herstellung von Faserbündeln |
WO2016102364A1 (de) | 2014-12-23 | 2016-06-30 | Hermann Reuschenbach | Vorrichtung und verfahren zur herstellung von fadenbündeln |
US20210106949A1 (en) | 2017-03-29 | 2021-04-15 | Gambro Lundia Ab | Device and process for the manufacture of hollow fiber membrane bundles |
Also Published As
Publication number | Publication date |
---|---|
EP4327918A1 (de) | 2024-02-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US9387945B2 (en) | Apparatus and method for manufacturing fiber bundles | |
EP3600629B1 (de) | Vorrichtung und verfahren zur herstellung von hohlfasermembranbündeln | |
KR101453231B1 (ko) | 중공사막 시트상물의 제조 방법, 중공사막 모듈의 제조 방법 및 중공사막 시트상물의 제조 장치 | |
US5470659A (en) | Hollow fibers | |
CA1328442C (fr) | Dispositif pour appliquer un enroulement filamentaire sur un support de forme quelconque et machine a bobiner universelle en comportant application | |
CA1061993A (fr) | Appareil a fibres creuses | |
FR2460030A1 (fr) | Condensateur enroule double et son procede de realisation | |
WO2010007283A1 (fr) | Procede et installation de fabrication d'un composant electronique enrobe de gomme | |
EP0056353A2 (de) | Maschine zum Schneiden, Falten und Fertigstellen von Bögen, ausgegeben aus aufgerollten Bahnen | |
CA1251674A (en) | Apparatus and method for wrapping an external tape support about a filter element assembly | |
WO2024042118A1 (en) | Device and process for the manufacture of hollow fiber membrane bundles | |
CN1112456A (zh) | 用于中空纤维束的缠绕管、制造方法及其制造设备 | |
HU209097B (en) | Apparatus for forming packing materials into tubular shape | |
EP2004534B1 (de) | Verfahren zur herstellung einer wicklung mit getrennten fäden | |
JP4842351B2 (ja) | 線状物束の包装装置 | |
US11759750B2 (en) | Hollow fiber membrane bundle | |
IT202100021314A1 (it) | Apparato e relativo metodo di avvolgimento di nastri di materiale per la produzione di dispositivi di accumulo di energia elettrica | |
WO2013065193A1 (ja) | 糸束体の包装方法及び包装装置並びに中空糸束の製造方法及び製造装置 | |
JP2011202300A (ja) | 糸束把持機構およびこれを用いた糸束の製造装置、製造方法 | |
RU2400366C2 (ru) | Машины и способы изготовления замкнутого изделия | |
CN107257708B (zh) | 用于操纵卷绕的线束的装置和方法 | |
WO2013065192A1 (ja) | 挟持部材及びそれを備えた糸束体の集束装置並びに中空糸束の製造装置 | |
WO2013065195A1 (ja) | 糸束体の切断装置及び中空糸束体の製造装置 | |
JPS647830B2 (de) | ||
JPS6351908A (ja) | 繊維束の成形装置 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 23758346 Country of ref document: EP Kind code of ref document: A1 |