WO2024037119A1 - Pompe d'assistance circulatoire d'intervention avec structure de guidage d'écoulement de sortie - Google Patents

Pompe d'assistance circulatoire d'intervention avec structure de guidage d'écoulement de sortie Download PDF

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Publication number
WO2024037119A1
WO2024037119A1 PCT/CN2023/097790 CN2023097790W WO2024037119A1 WO 2024037119 A1 WO2024037119 A1 WO 2024037119A1 CN 2023097790 W CN2023097790 W CN 2023097790W WO 2024037119 A1 WO2024037119 A1 WO 2024037119A1
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WO
WIPO (PCT)
Prior art keywords
blood
outlet
blood flow
impeller
interventional
Prior art date
Application number
PCT/CN2023/097790
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English (en)
Chinese (zh)
Inventor
韩志富
王献
张栩曼
马洪彬
丁明谦
王超
宋国刚
Original Assignee
航天泰心科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202210992732.8A external-priority patent/CN116262159A/zh
Priority claimed from CN202222175608.0U external-priority patent/CN219001739U/zh
Application filed by 航天泰心科技有限公司 filed Critical 航天泰心科技有限公司
Publication of WO2024037119A1 publication Critical patent/WO2024037119A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/165—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
    • A61M60/17—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart inside a ventricle, e.g. intraventricular balloon pumps

Definitions

  • the present application relates to the field of medical devices, and in particular to an interventional blood pump that is percutaneously inserted into a patient's blood vessel.
  • Interventional catheter pumps also known as interventional blood pumps, are mostly used in high-risk percutaneous coronary intervention (PCI) to reduce ventricular work and provide necessary circulatory support for cardiac recovery and early assessment of residual myocardial function.
  • PCI percutaneous coronary intervention
  • the most mature and advanced interventional catheter pump in the world is the Impella series developed by AbioMed. This type of blood pumping auxiliary device is introduced into the patient's heart through blood vessels. When working, the catheter pump inlet is placed in the ventricle and the outlet is placed in the artery. It pumps blood from the ventricle into the artery to ensure the patient's coronary artery and various organs throughout the body during PCI surgery. Blood perfusion reduces heart load.
  • This kind of catheter pump generally consists of a catheter, an impeller, a motor and other components, and includes a blood inlet located in the ventricle and a blood outlet located in the artery.
  • the structure of the blood inlet affects the angle and direction of blood inflow.
  • the impeller is the main power component of the catheter blood pump, which directly affects the effect of blood transportation and the destruction of blood cells; the function of the blood outlet is to pump the blood out of the impeller. Discharged downstream, affecting the stability and regularity of the blood flow field.
  • the outlet structure is to have an oval hollow-shaped hole directly opened on the metal shell at the impeller outlet.
  • the blood sucked into the conduit by the impeller directly scatters out of these holes, and the flow is relatively chaotic. To a certain extent, it leads to the dissipation of energy, weakens the blood pumping effect of the impeller, and also causes the blood scattered into the arteries to disrupt the regular flow field shape.
  • the blood flow when blood flows from the inlet into the pump body, due to the design of the inlet structure, the blood flow will have a certain degree of stagnation and vortex, which will hinder the flow or damage the blood to a certain extent.
  • An object of the present invention is to solve the above technical problems.
  • the present invention provides an interventional blood pump, which includes a pump body and a driving unit.
  • the pump body includes an impeller, a blood flow conduit, a blood flow inlet structure and a blood flow outlet structure that are drivingly connected to the driving unit.
  • the blood flow outlet structure includes an outlet housing, an outlet base and a guide vane structure disposed on the outlet base and connected to the outlet housing. At least a part of the impeller is accommodated in the outlet housing.
  • the guide vane structure is configured to convert the rotational motion of the blood flowing out of the impeller into primarily axial motion.
  • the blood flow outlet structure with the guide vane structure can collect the blood pumped by the impeller, guide its flow direction, and convert the rotational motion of the blood into mainly axial motion, thereby effectively promoting the blood flow.
  • the regularity of the field acts as a rectifier, thus avoiding outlet energy dissipation due to chaotic blood flow and improving the efficiency of the entire pump.
  • the guide vane structure in the present invention connects the outlet housing and the outlet base, and the impeller is rotatably fixed in the outlet housing.
  • the overall structure is stable and easy to manufacture.
  • the so-called "mainly axial movement” means that the axial component of the movement direction of the blood flowing out from the guide vane structure is greater than the circumferential component and the radial component, among which the axial, circumferential and radial directions are all based on the blood flow conduit.
  • the axial direction is the direction around which the impeller rotates.
  • the guide vane structure includes at least two blades, the blades are twisted blades or straight blades, and each blade includes a structure connected to the outlet housing and a straight blade respectively.
  • the blade tip and the blade root are connected by the outlet base, and the inlet edge and the outlet edge are connected between the blade tip and the blade root.
  • the inlet edge is located upstream of the outlet edge in the axial direction.
  • the so-called "twisted blade” refers to a blade whose blade shape is different from the blade root to the blade tip. The blade is not only twisted along the blade height direction, but also the blade's generatrix is curved.
  • This type of blade can better adapt to changes in blood flow direction in a small space, thereby guiding the blood flow direction closer to the axial direction more accurately.
  • "Straight blades” refer to blades whose root and tip extend along the axial direction.
  • the guide vane structure includes 3 to 5 blades. If the number of leaves is too small, it will not be able to perform a good rectification effect. If there are too many leaves, it will cause excessive local resistance and increase the risk of blood cell destruction.
  • the blade in the above-mentioned interventional blood pump, is a twisted blade, the blade root placement angle and the blade tip placement angle each gradually increase along the blood flow direction, and the blade root placement angle and the blade top placement angle gradually increase along the blood flow direction.
  • the blade tip installation angle at the inlet of the guide vane structure is basically consistent with the liquid flow angle of the blood flowing out of the impeller from the corresponding position, and the blade root installation angle is close to 90° at the outlet of the guide vane structure. , to reduce the circulation of blood at the outlet.
  • blade root installation angle refers to the angle between the tangent direction of the blade root profile and the tangent direction of the circumferential curve passing through that point at a certain point on the blade root.
  • blade tip placement angle refers to the angle between the tangent direction of the blade tip profile and the tangent direction of the circumferential curve passing through that point at a certain point on the blade tip.
  • fluid flow angle also refers to the angle between the blood flow direction and the tangent direction of the circumferential curve passing through that point at a certain point of the blood flow.
  • the blade root installation angle and the blade tip installation angle basically consistent with the liquid flow angle of the blood flow at the corresponding position, that is, the twisted blade is set along the blood flow direction, To prevent the high-speed blood flow from the impeller from colliding with the blades, destroying the blood cell structure and causing hemolysis.
  • the angle of the blade gradually changes.
  • the blade root installation angle becomes close to 90°, such as 85° to 90°, so that the blood flow in the guide vane structure
  • the outlet is directed to flow mainly along the axial direction, reducing swirl and losses along the way in the flow channel.
  • the blade tip placement angle is close to 90° at the outlet of the guide vane structure. This can better ensure that the blood flow is directed to flow mainly along the axial direction at the outlet of the guide vane structure.
  • the outlet placement angle of the blade tip cannot be close to 90°, because this will form a dead zone for blood flow, which is not conducive to smooth blood flow.
  • the thickness of the blade is 0.2mm to 0.4mm. This value range is obtained through many simulations and experiments. When the blade thickness is less than this range, the structural strength is not enough, and the accuracy of the manufacturing process cannot be guaranteed; and when the blade thickness is greater than this range, the blade cannot provide excellent fluid power. Chemical properties, and may block the flow channel, increase blood outflow speed, and have poor resistance to hemolysis.
  • the blood inflow The proximal end of the mouth structure is fixed on the distal end of the blood flow conduit or the distal end of the outlet housing.
  • the distal end of the blood flow inlet structure includes an inlet base fixed with a pigtail catheter.
  • the blood flow inlet structure includes A bell-shaped flow guide cone is provided on the inlet base and a blood suction port extending from the inlet base to the proximal end of the blood flow inlet structure.
  • the distal diameter of the flow guide cone is larger than the proximal diameter and includes a connection Its distal and proximal ends have tapered or concave guide surfaces.
  • the inventor replaces the boss-shaped part in the existing inlet structure with a tapered surface or a "bell-shaped" structure with a gentle arc.
  • This structure acts as a flow guide and can ensure smooth and stable blood flow. Flows into the catheter to reduce the impact on blood cells, ensure the integrity of blood cells, and reduce the pressure loss of blood in the catheter.
  • the rotation generatrix of the flow guide surface is a straight line, a concave arc or an elliptical curve, preferably a concave elliptic curve.
  • the outer diameter of the blood suction inlet is D and the axial length is H
  • the proximal diameter of the guide cone is d1 and the axial length is h
  • these parameters satisfy: 1.2D ⁇ H ⁇ 1.6D, 0.3D ⁇ d1 ⁇ 0.4D, 0.4D ⁇ h ⁇ 0.7D.
  • the impeller in the above-mentioned interventional blood pump, the impeller is directly connected to the output shaft of the drive unit, and the pump body sequentially includes the blood flow outlet structure from the proximal end to the distal end.
  • the impeller, the blood flow conduit and the blood flow inlet structure, the outlet base is fixed on the housing of the driving unit, and the proximal end of the blood flow conduit is fixed on the outlet housing.
  • the drive unit is also located within the body.
  • the connection methods between various parts of the pump body may be known in the art, such as bonding, threaded connection, laser welding, integrated injection molding, etc.
  • the impeller passes
  • the flexible shaft is connected to the output shaft of the driving unit, and the pump body includes the blood flow conduit, the blood flow outlet structure, the impeller and the blood flow inlet structure in sequence from the proximal end to the distal end.
  • the blood flow conduit is a radially expandable tube distally connected to the outlet housing, which is disposed outside the flexible shaft and extends over at least a portion of the length of the flexible shaft.
  • the impeller When the blood flowing out of the outlet structure enters the radially expandable tube so that it is in a radially expanded state, a blood flow channel is formed in the gap between the outlet structure and the flexible shaft, and the proximal end portion of the radially expandable tube is included in The working position is located at the blood outlet in the artery.
  • the drive unit may be located inside or outside the body.
  • the impeller is placed in front of the distal end of the blood flow conduit and is directly connected to the blood flow inlet structure, which can improve the blood pumping efficiency of the impeller.
  • Placing a blood flow outlet structure immediately adjacent to the impeller outlet can change the flow direction of the blood pumped by the impeller so that it mainly enters the radially expandable tube along the axial direction, reducing the outlet energy dissipation caused by chaotic blood flow. , improving the efficiency of the entire pump.
  • the radially expandable catheter can shrink to a very small outer diameter, close to the flexible shaft, thereby facilitating insertion into the blood vessel.
  • it can expand to a larger inner diameter, forming a gap between the flexible shaft and the flexible shaft.
  • the larger cross-section blood flow channel ensures the blood flow area.
  • the driving unit and the pump body are both located in the body, and the proximal end of the radially expandable tube is sealed ground to the distal extension of the drive unit.
  • the driving unit can also be located outside the body.
  • Such technical solutions already exist in the prior art. In this solution, the size and heat dissipation issues of the driving unit do not need to be considered.
  • the radially expandable tube is a flexible structure with relatively large instability. By connecting its proximal end to the rigid shell of the drive unit and its distal end to the outlet shell of the rigid blood flow outlet structure, both ends are It has rigid structural support, which is helpful to improve its stability.
  • the outlet structures are made of materials with good biocompatibility, such as implant-grade metal materials or implant-grade plastics.
  • Figure 1 is a schematic overall structural diagram of an interventional blood pump according to an embodiment of the present application.
  • FIG. 2 is a partial cross-sectional view of the proximal portion of the interventional blood pump shown in FIG. 1 .
  • FIG. 3 is a perspective view of the blood flow outlet structure of the interventional blood pump shown in FIG. 1 .
  • FIG. 4 is a perspective view of the flow guide structure of the blood flow outlet structure shown in FIG. 3 .
  • Figure 5 is a three-dimensional view of the air guide structure shown in Figure 4, in which the entity of the guide vane structure is hidden and only the profile lines of each blade root are retained.
  • FIG. 6 is a partial cross-sectional view of the interventional blood pump shown in FIG. 1 .
  • FIG. 7 is an axial cross-sectional view of the blood flow inlet structure of the interventional blood pump shown in FIG. 1 .
  • FIG. 8 is a schematic diagram of the flow guide cone of the blood flow inlet structure shown in FIG. 7 .
  • Figure 9 is a schematic overall structural diagram of an interventional blood pump according to another embodiment of the present application.
  • FIG. 10 is a schematic perspective view of the blood flow outlet structure of the interventional blood pump shown in FIG. 9 .
  • FIG. 11 is a partial cross-sectional view of the distal portion of the interventional blood pump shown in FIG. 9 .
  • 80 Blade; 81: Inlet edge; 82: Blade top; 83: Exit edge; 84: Blade root; 840: Blade root profile; 85: Connection structure.
  • proximal end and distal end are relative to the operator of the interventional blood pump.
  • the part of a component close to the operator is the proximal end, and the part far from the operator is the proximal end. Part is remote.
  • FIG. 1 schematically shows a part of the structure of an interventional blood pump according to an embodiment of the present invention.
  • the blood pump can be used as a ventricular assist device (VAD) to assist the ventricle in high-risk percutaneous coronary intervention.
  • VAD ventricular assist device
  • the blood pump includes a pump body located at the distal end during operation and a driving unit 6 located at the proximal end.
  • the driving unit 6 is a motor, such as a coreless motor.
  • any driving unit eg, a hydraulic motor
  • the blood pump also includes a hollow interventional catheter (not shown), the distal end of which is connected to the proximal end of the drive unit 6 . During surgical intervention, the interventional catheter plays a pushing role.
  • the pump body from the distal end to the proximal end, the pump body includes a pigtail catheter 1 , a blood flow inlet structure 2 , a blood flow catheter 3 , a rotatable impeller 4 and a blood flow outlet structure 5 .
  • the impeller 4 is directly connected to the output shaft of the drive unit 6 and includes impeller blades 42.
  • the blood inlet structure 2 is provided with a blood suction inlet 24. The blood pumped by the impeller flows out from the blood outlet structure 5 and enters the artery.
  • the distal end of the pigtail catheter 1 is curved, which can prevent the pump body from touching the ventricular wall and causing unnecessary damage to the ventricular wall.
  • the blood flow outlet structure 5 includes an outlet housing 52 , an outlet base 54 and a guide vane structure 56 disposed on the outlet base 54 and connected to the outlet housing 52 .
  • a portion of the impeller 4 is housed within the outlet housing 52 .
  • the outlet base 54 is fixed to the housing of the drive unit 6 and the proximal end of the blood flow conduit 3 is fixed to the outlet housing 52 .
  • the connections between the components can be in various ways known and applicable in the art.
  • the blood flow conduit 3 and the outlet housing 52 of the blood flow outlet structure 5 are connected through adhesive; the outlet housing 52 and the drive unit 6 are connected through adhesive.
  • Laser welding connection; the impeller 4 and the drive motor 6 are connected through structural adhesive bonding, threaded connection or integrated injection molding. The present invention does not limit this. When one component is fixed to another component, their assembly only needs to have the characteristics of "axial centering".
  • the guide vane structure 56 is configured to convert the rotational movement of the blood flowing out of the impeller 4 into a predominantly axial movement.
  • the guide vane structure 56 includes five blades 80 , each blade 80 has the same shape and is evenly distributed along the axial direction. The thickness of the blade 80 ranges from 0.2mm to 0.4mm.
  • Each blade 80 includes a blade tip 82 connected to the outlet casing 52 and a blade root 84 connected to the outlet base 54 .
  • the blade tip 82 and the blade root 84 are connected by an inlet edge 81 and an outlet edge 83 . In the axial direction, the inlet edge 81 is located upstream of the outlet edge 83 .
  • the blade 80 is a twisted blade, that is, the blade is twisted along the blade height direction and its generatrix is also curved.
  • the entity of the guide vane structure 56 is hidden in FIG. 5 and only the blade root profile lines 840 are retained, and the circumferential curve 540 is shown.
  • the tangent direction L2 of the blade root profile 840 and the tangent direction L1 of the circumferential curve 540 passing through this point are The included angle C is the blade root installation angle at the entrance.
  • Blade refers to the angle between the tangent direction of the blade root profile at that point and the tangent direction of the circumferential curve passing through that point.
  • blade tip placement angle refers to the angle between the tangent direction of the blade tip profile and the tangent direction of the circumferential curve passing through that point at a certain point on the blade tip.
  • the high-speed rotation of the impeller 4 causes the blood pumped by it to have a high rotation speed
  • the shape of the impeller blades 42 is such that the liquid flow angles at different radial positions of the blood flow at the impeller outlet are different.
  • the installation angle of the blade root and the installation angle of the blade tip are basically consistent with the liquid flow angle of the blood flow at the corresponding position, that is, the twisted blade 80 is set to follow
  • the direction of the blood flow is to prevent the high-speed blood flow from the impeller 4 from directly colliding with the blades 80 .
  • the angle of the blade 80 gradually changes, so that at the outlet of the guide vane structure 56, the blade root installation angle becomes close to 90°, such as 85° to 90°, so as to facilitate blood flow.
  • the flow at the outlet of the guide vane structure 56 is directed mainly along the axial direction, reducing swirl and along-the-way losses in the flow channel.
  • the inlet placement angle of the blade tip ranges from 40° to 50°
  • the inlet placement angle of the blade root ranges from 51° to 61°
  • the outlet placement angle of the blade tip ranges from 55° to 55°. ° to 65°.
  • the outlet placement angle of the blade tip is also close to 90°, it can better ensure that the blood flow is directed to flow mainly along the axial direction at the outlet of the guide vane structure.
  • the axial length of the blade tip 82 is relatively small. If the guide vane profile is forcibly twisted, the outlet placement angle of the blade tip 82 will also be close to 90° will form a dead zone of blood flow, which is not conducive to the smooth flow of blood.
  • the outlet housing 52 includes an inner diameter change adjacent to the expanded portion 520 connected to the flow guide structure 56. Specifically, its inner diameter increases from the upstream to the downstream direction of the blood flow. big.
  • This arrangement together with the flow guide structure 56, gradually increases the blood flow area from S1 at the outlet of the impeller 4 to S2 at the outlet of the blood flow outlet structure 5, forming an expansion section, thereby converting part of the kinetic energy of the blood flow into Pressure potential energy plays a role in stabilizing blood flow.
  • Figure 7 is an axial cross-sectional view of the blood flow inlet structure.
  • the distal end of the blood flow inlet structure 2 includes an inlet base 21 to which the pigtail catheter 1 is fixed. More specifically, the inlet base 21 includes a pigtail catheter connection seat 23 with a smaller outer diameter at the distal end.
  • the pigtail catheter 1 is fixed to the pigtail catheter connection seat 23 by threading or glueing, or threading and glueing.
  • the inlet base 21 is also penetrated by an axially extending guide wire perforation 25 for providing guidance for the blood pump to enter the artery and the heart through the guide wire.
  • the portion where the proximal end of the inlet base 21 is connected to the blood suction inlet 24 forms a bell-shaped guide cone 22 .
  • the so-called "bell-shaped" flow guide cone refers to its three-dimensional shape like a bell with two ends of different sizes connected by smooth curves.
  • the distal diameter of the flow guide cone 22 is larger than the proximal diameter, and its distal end and proximal end are connected by a smooth flow guide surface 20 .
  • the rotation generatrix of the flow guide surface 20 may be a straight line, a concave circular or an elliptical curve, and is preferably a concave elliptical curve as shown in FIG. 7 .
  • the distal diameter of the flow guide cone 22 is the same as the outer contour diameter D of the blood flow inlet structure 2, the proximal diameter is d1, and the axial length is h.
  • the outer contour diameter D is the input parameter of the catheter blood pump and needs to be determined according to the product application range. Generally, 4 to 7 mm is selected.
  • H is the axial height of the blood suction port, which preferably satisfies 1.2D ⁇ H ⁇ 1.6D to provide good guidance for blood flow.
  • FIG 9 shows an interventional blood pump according to another embodiment of the present application.
  • the impeller 4 is connected to the output shaft of the drive unit 6 through a flexible shaft 7.
  • the flexible shaft 7 adopts a structure known in the art, including a flexible shaft 70 used to transmit the torque of the drive unit 6 to the impeller 4 and drive it to rotate at high speed, a flat wire spring tube 72 sleeved outside the flexible shaft, and a sleeved A sealing hose 74 outside the flat wire spring tube 72 .
  • the driving unit 6 can be located inside the body or outside the body.
  • the pump body includes a pigtail catheter 1, a blood flow inlet structure 2, a rotatable impeller 4, a blood flow outlet structure 5 and a blood flow catheter 3.
  • the blood inlet structure 2 is provided with a blood suction inlet 24, and the blood pumped by the impeller 4 passes through the blood outlet structure 5. It flows out and enters the blood flow conduit 3.
  • the blood flow conduit 3 is formed by a radially expandable tube 30 arranged outside the flexible shaft 7.
  • the gap between the radially expandable tube 30 and the flexible shaft 7 forms a blood flow channel, which can be radially expanded.
  • the proximal portion of the expansion tube 30 includes a blood outlet 302 located in the artery in the operating position.
  • the distal end of the radially expandable catheter 5 can be fixed to the outer surface of the proximal end of the blood outflow outlet structure 5 by gluing, heat welding, or the like.
  • the blood outlets 302 are a plurality of openings opened on the proximal wall of the radially expandable catheter 5.
  • the shape may be, for example, circular, oval, etc., and the number may be, for example, 3 to 6, preferably evenly distributed along the circumferential direction.
  • FIG. 10 schematically shows a perspective view of the blood flow outlet structure 5 in the above embodiment.
  • the blood flow outlet structure 5 includes an outlet housing 52 , an outlet base 54 , and a guide vane structure 56 disposed on the outlet base 54 and connected to the outlet housing 52 .
  • the guide vane structure 56 includes five twisted blades 80, each blade 80 has the same shape and is evenly distributed along the axial direction.
  • Each blade 80 includes a blade tip 82 connected to the outlet housing 52 and a blade root 84 connected to the outlet base 54 .
  • the blade root installation angle and the blade tip installation angle are basically consistent with the liquid flow angle of the blood flow at the corresponding position, that is, the blade 80 is bent and twisted. It is set along the direction of blood flow to avoid direct collision between the high-speed blood flow flowing out of the impeller 4 and the blades 80, thereby reducing damage to blood cells.
  • the angle of the blade 80 gradually changes, so that at the outlet of the guide vane structure 56, the blade root installation angle becomes close to 90°, such as 85° to 90°, so as to facilitate blood flow.
  • the flow at the outlet of the guide vane structure 56 is directed mainly along the axial direction, reducing swirl and along-the-way losses in the flow channel.
  • the blade tip installation angle at the outlet of the guide vane structure 56 is also close to 90°, which is more conducive to ensuring that the blood flow is at the outlet of the guide vane structure Different radial positions are directed to flow primarily in the axial direction.
  • the difference from the embodiment shown in FIG. 3 is that in the embodiment shown in FIG. 10 , the blade tip 82 is connected to the outlet housing 52 through the connecting structure 85 to obtain a stronger and more stable connection.
  • the blood flow outlet structure 5 shown in FIG. 10 is manufactured by machining, for example.
  • the blood flow outlet structure 5 shown in Figure 10 itself does not include changes in inner diameter. From the outlet of the impeller 4 to the outlet of the blood flow outlet structure 5, the flow of blood changes. The flow area does not increase significantly. In fact, in this embodiment In the formula, the expandable tube 30 is used to increase the flow area and thereby stabilize the blood flow.
  • the structural features and contour parameters of the blood flow inlet structure 2, especially the bell-shaped guide cone 22, are the same as those of the previous embodiment. The same or similar features described in an embodiment will not be described again here.
  • the proximal end of the blood flow inlet structure 2 is directly connected to the outlet housing 52 of the blood flow outlet structure 5 .
  • the impeller 4 is located between the blood flow inlet structure 2 and the blood flow outlet structure 5 , and most of it is located within the mouth housing 52 .
  • the outlet base 54 of the blood flow outlet structure 5 is also provided with a bearing 58 for the impeller shaft 78 .
  • the impeller shaft 78 is rotatably supported in the bearing 58 and fixed to the distal end of the flexible shaft 70 .
  • the fixing can be achieved by any suitable means, such as adhesive bonding, laser welding, crimping, snapping, etc.
  • the pump body also includes a tubular connector 76 secured to the proximal end of the blood flow outlet structure, the tubular connector 76 having a distal region and a proximal region, the distal region having an outer diameter greater than the outer diameter of the proximal region, the distal region connecting To the distal end of the sealing hose 74, the proximal area is connected to the distal end of the flat wire spring tube 72.
  • the tubular connector 76 is also made of rigid material. In this way, the entire distal end of the flexible shaft 4 is connected to the rigid body, which can obtain good support and improve stability.

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  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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Abstract

L'invention concerne une pompe d'assistance circulatoire d'intervention, comprenant un corps de pompe et une unité d'entraînement (6). Le corps de pompe comprend une hélice (4), un cathéter d'écoulement sanguin (3), une structure d'entrée d'écoulement sanguin (2) et une structure de sortie d'écoulement sanguin (5) qui sont en liaison d'entraînement avec l'unité d'entraînement (6), la structure de sortie d'écoulement sanguin (5) comprenant un boîtier de sortie (52), une base de sortie (54) et une structure d'aube directrice (56) disposée sur la base de sortie (54) et reliée au boîtier de sortie (52). Au moins une partie de la roue (4) est logée dans le boîtier de sortie (52). La structure d'aube directrice (56) est conçue pour pouvoir convertir le mouvement de rotation du sang s'écoulant hors de l'hélice (4) en un mouvement principalement axial. La structure de sortie d'écoulement sanguin (5) avec la structure d'aube directrice (56) peut favoriser efficacement la régularité d'un champ d'écoulement sanguin et réduire l'effet destructeur sur les globules rouges au moyen de la commande de la direction d'écoulement du sang pompé par l'hélice (4).
PCT/CN2023/097790 2022-08-18 2023-06-01 Pompe d'assistance circulatoire d'intervention avec structure de guidage d'écoulement de sortie WO2024037119A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN202210992732.8A CN116262159A (zh) 2022-08-18 2022-08-18 具有出口导流结构的介入式血泵
CN202210992732.8 2022-08-18
CN202222175608.0 2022-08-18
CN202222175608.0U CN219001739U (zh) 2022-08-18 2022-08-18 介入式血泵

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WO2024037119A1 true WO2024037119A1 (fr) 2024-02-22

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Citations (8)

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