WO2024011898A1 - Procédé et système d'imagerie tridimensionnelle à double bras en c, basés sur un collimateur multi-lames à réglage dynamique - Google Patents

Procédé et système d'imagerie tridimensionnelle à double bras en c, basés sur un collimateur multi-lames à réglage dynamique Download PDF

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Publication number
WO2024011898A1
WO2024011898A1 PCT/CN2023/075304 CN2023075304W WO2024011898A1 WO 2024011898 A1 WO2024011898 A1 WO 2024011898A1 CN 2023075304 W CN2023075304 W CN 2023075304W WO 2024011898 A1 WO2024011898 A1 WO 2024011898A1
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imaging
dimensional
arm
initial
grating
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PCT/CN2023/075304
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English (en)
Chinese (zh)
Inventor
张纪庄
郭咏梅
郭咏阳
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康达洲际医疗器械有限公司
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Publication of WO2024011898A1 publication Critical patent/WO2024011898A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/54—Control of apparatus or devices for radiation diagnosis
    • A61B6/542—Control of apparatus or devices for radiation diagnosis involving control of exposure
    • A61B6/544—Control of apparatus or devices for radiation diagnosis involving control of exposure dependent on patient size
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/06—Diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/48—Diagnostic techniques
    • A61B6/488—Diagnostic techniques involving pre-scan acquisition

Definitions

  • the invention relates to the field of image processing technology, and in particular to a dynamically adjustable dual C-arm three-dimensional imaging method and system based on multi-leaf gratings.
  • DSA Digital Subtraction Angiography
  • C-arm C-arm X-ray machine
  • Three-dimensional C-arm/DSA is based on the traditional two-dimensional C-arm/DSA technology. It collects a series of projection data within a certain angle range around the imaging area and performs three-dimensional image reconstruction.
  • the three-dimensional C-arm/DS stereoscopic image Compared with the two-dimensional C-arm/DSA image, the three-dimensional C-arm/DS stereoscopic image has no overlap, is clearer, and provides more accurate three-dimensional spatial positioning. It can also generate transverse, sagittal, coronal, or other arbitrary section images to improve surgical procedures. Accuracy; however, on the other hand, three-dimensional imaging often requires higher imaging dose, and some clinical applications require multiple three-dimensional imaging, making the problem of high imaging dose more prominent. How to reduce the imaging dose of three-dimensional C-arm/DSA has become an urgent problem that needs to be solved.
  • Existing C-arm/DSA equipment often uses a beam limiting device or collimating plate.
  • the beam limiting device or collimating plate is located between the X-ray tube and the tissue being inspected.
  • the area within the collimating window is the imaging beam area, and the X-ray passes through the open
  • the collimation window area is projected to the tissue under examination, and is collected and analyzed by the detector after passing through the tissue to obtain diagnostic information; X-rays outside the collimation window or outside the imaging beam area do not perform effective imaging and only increase harmful
  • the radiation dose is blocked by the metal beam limiting device or collimating plate and is not projected to the tissue being examined, thereby reducing the radiation dose.
  • the size of the opening (beam spot) of the traditional beam limiting device or collimating plate used in C-arm/DSA equipment is adjustable, the shape of the opening will not be adjusted accordingly to the shape of the imaging area. This is This results in unnecessary radiation dose being absorbed by the tissue being examined, causing unnecessary tissue damage.
  • the present invention proposes a dynamically adjustable dual C-arm three-dimensional imaging method based on a multi-leaf grating.
  • the multi-leaf grating is composed of several pairs of adjustable It consists of split-type grating pairs that telescope in opposite directions. Each split-type grating pair is aligned in a row to form a grating surface perpendicular to the ray direction, including the steps:
  • the acquisition conditions of the three-dimensional basal imaging include: acquisition through intraoperative initial imaging and acquisition through preoperative initial imaging.
  • step S1 when the three-dimensional imaging of the base is obtained through preoperative initial imaging, the steps after step S1 are:
  • S20 Determine whether the position of the target object is the same as that of the initial preoperative imaging. If not, adjust the position of the target object.
  • the line connecting the light pass area and the current maximum projection density area at the same position is parallel to the ray direction.
  • a first preset dose is used to obtain three-dimensional imaging of the substrate, and during adaptive imaging, a second preset dose is used to obtain projection data, and the first preset dose is greater than the second preset dose.
  • the present invention also proposes a dynamically adjustable dual C-arm three-dimensional imaging system based on multi-leaf gratings.
  • the multi-leaf gratings are composed of several pairs of split grating pairs that can be retracted in opposite directions. Each split grating pair is arranged in a row. Fitted to a grating surface perpendicular to the ray direction, including:
  • the initial imaging unit is used to obtain the base three-dimensional imaging of the target object in the fully retracted state of each split grating during the angle adjustment process of the double C-arm gantry during initial imaging;
  • the region extraction unit is used to extract the three-dimensional region of interest in the three-dimensional basal imaging map according to clinical needs;
  • the density map extraction unit is used to extract the maximum projection density map at the corresponding frame angle from the three-dimensional area of interest based on the current preset frame angle of each single C-arm;
  • the grating adjustment unit is used to control the opposite extension of each split grating pair in the corresponding single C arm according to the maximum projection density map, and to keep the grating surface in the ray direction with a light pass area that is suitable for the current maximum projection density area;
  • the adaptive imaging unit is used to control the operation of the ray emitting tube and collect the projection data at the current preset frame angle during the adaptive imaging process through the flat-panel receiver;
  • the rack adjustment unit is used to adjust the rack angle to the next preset rack angle before the projection data collection is completed;
  • the three-dimensional reconstruction unit is used to reconstruct the three-dimensional imaging of the target object based on the projection data collected at each frame angle of the double C-arm after the projection data collection is completed.
  • the three-dimensional imaging of the base is obtained by: obtaining through intraoperative initial imaging, and obtaining through preoperative initial imaging.
  • the adaptive imaging unit also includes:
  • the registration unit is used to provide body position registration guidance information when the position of the target object is different from the initial preoperative imaging.
  • the line connecting the light pass area and the current maximum projection density area at the same position is parallel to the ray direction.
  • a first preset dose is used to obtain three-dimensional imaging of the substrate, and during adaptive imaging, a second preset dose is used to obtain projection data, and the first preset dose is greater than the second preset dose.
  • the present invention at least contains the following beneficial effects:
  • Figure 1 is a step diagram of a dual C-arm three-dimensional imaging method based on dynamically adjustable multi-leaf gratings
  • Figure 2 is a structural diagram of a dual C-arm three-dimensional imaging system based on dynamically adjustable multi-leaf gratings.
  • the dual C-arm system has two sets of C-arm systems (two sets of ray emission tubes-flat receivers, C-arm frame motion devices, etc.).
  • the two sets of C-arm systems are one suspended and one floor-mounted. formula, coordinate movement and imaging.
  • the dual C-arm system has more flexible imaging, higher temporal resolution, and fewer motion artifacts. But like the single C-arm system, the imaging dose of the dual C-arm system is also an issue that needs to be solved urgently.
  • the present invention proposes a dynamically adjustable dual C-arm three-dimensional imaging method based on multi-leaf grating.
  • the multi-leaf grating It consists of several pairs of split-type grating pairs that can be retracted in opposite directions. Each split-type grating pair is aligned in a row to form a grating surface perpendicular to the ray direction, including the steps:
  • the present invention puts forward an idea, that is, is it possible to maintain the acquisition of only the projection data of the area of interest during the C-arm imaging angle adjustment process? If this can be achieved, unnecessary imaging dose exposure to non-interest areas can be avoided. At the same time, since there is no scattering interference from rays outside the area, the imaging dose in the area of interest can be appropriately reduced while ensuring imaging quality.
  • the present invention proposes an improved three-dimensional imaging method for dual C-arms.
  • the imaging dose under conventional C-arm scanning that is, the first preset dose ).
  • the adaptive scan can be entered.
  • the present invention proposes that in adaptive scanning, according to the current preset gantry angle of each single C-arm, the maximum projection density map at the corresponding gantry angle is first extracted from the three-dimensional area of interest. Then, according to the maximum projection density map, each split grating pair can be controlled to extend in opposite directions, so that the grating surface retains a luminous flux area in the ray direction that is suitable for the current maximum projection density area.
  • the line connecting the luminous flux area and the current maximum projection density area at the same position is parallel to the ray direction.
  • the advantage of this setting is that when the ray passes through the light pass area, since the line connecting the light pass area and the current maximum projection density area at the same position is parallel to the direction of the ray, the ray will only illuminate the direction of the current frame angle. Corresponding area of interest plane Therefore, no excess imaging dose will be irradiated to planes other than the plane of the area of interest, reducing the damage of rays to tissues. At the same time, since the influence of ray scattering in other non-target irradiation areas is avoided, the imaging dose can be appropriately reduced while ensuring the imaging quality (that is, the second preset dose, the specific dose can be obtained according to experiments).
  • the rack After controlling the operation of the launch tube and collecting the projection data at the current preset rack angle through the flat-panel receiver, and the projection data is before the collection is completed (that is, the support interventional diagnosis and treatment has not ended), the rack can be adjusted. angle to the next preset rack angle.
  • the split grating pair In the process of rack angle adjustment, in order to improve the collection speed of projection data, the split grating pair is adaptively adjusted during the rack angle adjustment process, so that its luminous area range is adaptive to the next preset machine. The maximum projection density area corresponding to the frame angle.
  • the acquisition of three-dimensional basal imaging can be divided into two situations, one is obtained through initial intraoperative imaging, and the other is obtained through initial preoperative imaging.
  • the target may require other operations midway and the initial imaging cannot be completed during the operation.
  • the three-dimensional region of interest obtained from the initial imaging must be used in adaptive imaging. It is necessary to ensure that the position of the front and rear three-dimensional areas of interest remains unchanged, that is, the body position of the target object needs to remain consistent. The present invention is aimed at this situation.
  • the steps after step S1 are also included:
  • S20 Determine whether the position of the target object is the same as that of the initial preoperative imaging. If not, adjust the position of the target object.
  • the relative positions of the imaging components in the dual C-arm imaging system also need to be adjusted to be consistent.
  • the specific registration technology is conventional and will not be described in detail here. .
  • Leaf gratings are composed of several split-type grating pairs that can be retracted in opposite directions. Each split-type grating pair is aligned in a row to form a grating surface perpendicular to the ray direction, including:
  • the initial imaging unit is used to obtain the base three-dimensional imaging of the target object in the fully retracted state of each split grating during the angle adjustment process of the double C-arm gantry during initial imaging;
  • the region extraction unit is used to extract the three-dimensional region of interest in the three-dimensional basal imaging map according to clinical needs;
  • the density map extraction unit is used to extract the maximum projection density map at the corresponding frame angle from the three-dimensional area of interest based on the current preset frame angle of each single C-arm;
  • the grating adjustment unit is used to control the opposite extension of each split grating pair in the corresponding single C arm according to the maximum projection density map, and to keep the grating surface in the ray direction with a light pass area that is suitable for the current maximum projection density area;
  • the adaptive imaging unit is used to control the operation of the ray emitting tube and collect the projection data at the current preset frame angle during the adaptive imaging process through the flat-panel receiver;
  • the rack adjustment unit is used to adjust the rack angle to the next preset rack angle before the projection data collection is completed;
  • the three-dimensional reconstruction unit is used to reconstruct the three-dimensional imaging of the target object based on the projection data collected at each frame angle of the double C-arm after the projection data collection is completed.
  • the acquisition of the three-dimensional basal imaging includes: acquisition through intraoperative initial imaging and acquisition through preoperative initial imaging.
  • the adaptive imaging unit also includes:
  • the registration unit is used to provide body position registration guidance information when the position of the target object is different from the initial preoperative imaging.
  • the line connecting the light pass area and the current maximum projection density area at the same position is parallel to the ray direction.
  • a first preset dose is used to obtain three-dimensional imaging of the substrate, and during adaptive imaging, a second preset dose is used to obtain projection data, and the first preset dose is greater than the second preset dose.
  • the present invention is a dynamically adjustable dual C-arm three-dimensional imaging method and system based on multi-leaf gratings, which performs adaptive range adjustment of light flux based on the identification of the maximum projection density area at each frame angle. Area adjustment to avoid non-interesting areas of the target being irradiated by rays;.
  • Three-dimensional imaging of the substrate is obtained through normal dose irradiation during initial imaging, and during the three-dimensional imaging of the substrate Based on the screening of the area of interest, the multi-leaf grating light-passage area is dynamically adjusted during the adaptive imaging process (that is, during the support interventional diagnosis and treatment process) according to the area of interest, and the projection data is collected and Three-dimensional imaging splicing acquisition greatly reduces the overall radiation dose during interventional diagnosis and treatment.
  • connection can be a fixed connection, a detachable connection, or an integral body; It can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be an internal connection between two elements or an interactive relationship between two elements, unless otherwise clearly limited.
  • fixing can be a fixed connection, a detachable connection, or an integral body; It can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be an internal connection between two elements or an interactive relationship between two elements, unless otherwise clearly limited.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Abstract

La présente invention a trait au domaine technique du traitement d'images. L'invention concerne un procédé et un système d'imagerie tridimensionnelle à double bras en C, basés sur un collimateur multi-lames à réglage dynamique. Le procédé comprend les étapes consistant : à acquérir une image de substrat tridimensionnel, obtenue au moyen de chaque collimateur de type divisé, d'un objet cible dans un état complètement rétracté pendant un processus de réglage d'angle de crémaillère des doubles bras en C ; à sélectionner une région d'intérêt tridimensionnelle ; à extraire de celle-ci une carte de densité de projection maximale à un angle de crémaillère correspondant ; à permettre à une surface de collimateur de retenir, dans une direction de rayon, une région de traversée de lumière dans une plage adaptative à la région de densité de projection maximale actuelle ; et à commander le fonctionnement d'un tube d'ampoule d'émission de rayons, et à collecter, au moyen d'un récepteur de panneau plat, des données de projection à l'angle de crémaillère prédéfini courant, pendant un processus d'imagerie adaptative.
PCT/CN2023/075304 2022-07-15 2023-02-10 Procédé et système d'imagerie tridimensionnelle à double bras en c, basés sur un collimateur multi-lames à réglage dynamique WO2024011898A1 (fr)

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CN202210831054.7A CN114886445B (zh) 2022-07-15 2022-07-15 一种基于多叶光栅动态可调的双c臂三维成像方法与系统

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