WO2024006752A3 - Simultaneous intensity and energy modulation and compensation in radiotherapy, methods of radiotherapy, and systems of radiotherapy - Google Patents

Simultaneous intensity and energy modulation and compensation in radiotherapy, methods of radiotherapy, and systems of radiotherapy Download PDF

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Publication number
WO2024006752A3
WO2024006752A3 PCT/US2023/069160 US2023069160W WO2024006752A3 WO 2024006752 A3 WO2024006752 A3 WO 2024006752A3 US 2023069160 W US2023069160 W US 2023069160W WO 2024006752 A3 WO2024006752 A3 WO 2024006752A3
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WO
WIPO (PCT)
Prior art keywords
radiotherapy
systems
methods
patient
compensation
Prior art date
Application number
PCT/US2023/069160
Other languages
French (fr)
Other versions
WO2024006752A2 (en
Inventor
Shuang Zhou
Tiezhi Zhang
Steven BIEGALSKI
Cristina OANCEA
Minglei Kang
Wei Liu
II Charles SIMONE
Niklas WAHLS
Liyong Lin
Ruirui Liu
Nathan Harrison
Jeffrey BRADLEY
Kristin HIGGINS
William Dynan
Jun Zhou
Xiaofeng Yang
Serdar CHARYYEV
Alexander STANFORTH
Original Assignee
Emory University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emory University filed Critical Emory University
Publication of WO2024006752A2 publication Critical patent/WO2024006752A2/en
Publication of WO2024006752A3 publication Critical patent/WO2024006752A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077—Beam delivery systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1087—Ions; Protons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1089—Electrons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • A61N2005/1095—Elements inserted into the radiation path within the system, e.g. filters or wedges

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The present disclosure provides for systems and methods for designing patient-specific sparse passive filters, for example compensation and modulation components, for simultaneous intensity and energy modulation in energetic entity or particle (e.g., proton) therapy, radiation therapy methods and systems, method for treating cancer in a patient or animal subject, method of optimizing an administration plan in particle FLASH radiotherapy or non-FLASH radiotherapy, configuration of the device or system to effectively place the patient-specific sparse passive filter, and the like.
PCT/US2023/069160 2022-06-27 2023-06-27 Simultaneous intensity and energy modulation and compensation in radiotherapy, methods of radiotherapy, and systems of radiotherapy WO2024006752A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US202263355750P 2022-06-27 2022-06-27
US63/355,750 2022-06-27
US202263433202P 2022-12-16 2022-12-16
US63/433,202 2022-12-16
US202363446479P 2023-02-17 2023-02-17
US63/446,479 2023-02-17

Publications (2)

Publication Number Publication Date
WO2024006752A2 WO2024006752A2 (en) 2024-01-04
WO2024006752A3 true WO2024006752A3 (en) 2024-03-14

Family

ID=89381603

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2023/069160 WO2024006752A2 (en) 2022-06-27 2023-06-27 Simultaneous intensity and energy modulation and compensation in radiotherapy, methods of radiotherapy, and systems of radiotherapy

Country Status (1)

Country Link
WO (1) WO2024006752A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030142895A1 (en) * 2002-01-25 2003-07-31 Aaron Bond Method of fabricating a monolithic expanded beam mode electroabsorption modulator
US20200338364A1 (en) * 2019-04-26 2020-10-29 Elekta, Inc. Method of providing proton radiation therapy utilizing periodic motion
US20210121150A1 (en) * 2018-07-09 2021-04-29 William Beaumont Hospital On-board charged particle therapy computed tomography system
US20220118282A1 (en) * 2020-10-16 2022-04-21 Elekta, Inc. Particle arc treatment planning

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030142895A1 (en) * 2002-01-25 2003-07-31 Aaron Bond Method of fabricating a monolithic expanded beam mode electroabsorption modulator
US20210121150A1 (en) * 2018-07-09 2021-04-29 William Beaumont Hospital On-board charged particle therapy computed tomography system
US20200338364A1 (en) * 2019-04-26 2020-10-29 Elekta, Inc. Method of providing proton radiation therapy utilizing periodic motion
US20220118282A1 (en) * 2020-10-16 2022-04-21 Elekta, Inc. Particle arc treatment planning

Also Published As

Publication number Publication date
WO2024006752A2 (en) 2024-01-04

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