CN107412963A - Novel radiation treatment treatment planning systems - Google Patents

Novel radiation treatment treatment planning systems Download PDF

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Publication number
CN107412963A
CN107412963A CN201710618443.0A CN201710618443A CN107412963A CN 107412963 A CN107412963 A CN 107412963A CN 201710618443 A CN201710618443 A CN 201710618443A CN 107412963 A CN107412963 A CN 107412963A
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China
Prior art keywords
radiotherapy
magnetic therapy
treatment
dosimetry
space
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CN201710618443.0A
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CN107412963B (en
Inventor
鲁旭尉
刘怀
刘峰
尹可
罗英
郭戈杨
胡英
尹宏
李宇
瞿琮
王勇
李煜
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Hunan Cancer Hospital
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Hunan Cancer Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103Treatment planning systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/002Magnetotherapy in combination with another treatment

Abstract

The invention discloses a kind of novel radiation treatment treatment planning systems, including radiotherapy planning module, magnetic therapy schedule module, magnetic therapy combined radiotherapy computing module and output module;Radiotherapy planning module obtain independent radiotherapy when radiotherapy in the treatment space each position Radiotherapy dosimetry and input magnetic therapy combined radiotherapy computing module;Magnetic therapy schedule module in the magnetic therapy dosage of space each position and inputs magnetic therapy combined radiotherapy computing module for magnetotherapy treatment when calculating magnetic therapy combined radiotherapy;When magnetic therapy combined radiotherapy is calculated in magnetic therapy combined radiotherapy computing module radiotherapy in the treatment each position in space Radiotherapy dosimetry and upload output module;Output module exports final treatment plan.The present invention is identical for criterion with the biological effect of living organism, there is provided the system of a treatment plan that can accurately generate magnetic therapy combined radiotherapy;The radiotherapy that the present invention is capable of automatic and accurate calculating patient is measured and automatically generates treatment plan, and simple and convenient, science is directly perceived, and effectively medical worker can be instructed.

Description

Novel radiation treatment treatment planning systems
Technical field
Present invention relates particularly to a kind of novel radiation treatment treatment planning systems.
Background technology
With the development of economic technology, the living standard of people is also improving constantly.But along with people's living standard Raising, the operating pressure and working strength of people be also increasing.In addition, with economic technology and industrial expansion, environment Pollution problem also becomes increasingly conspicuous.
Tumour is the significant threat of human health, with people's work and the increase of life stress, and environmental problem Increasingly highlight, the trend risen year by year is also presented in the morbidity amount of tumour.
At present, the radiotherapy of tumour is a kind of one of comparatively effective therapeutic modality.Tumour radiotherapy is profit With a kind of local therapeutic approaches of radiation cure tumour.About 70% cancer patient needs to use during treating cancer Radiotherapy, there are about 40% cancer can be effected a radical cure with radiotherapy, effect and status day of the radiotherapy in oncotherapy Benefit is prominent, it has also become treats one of Main Means of malignant tumour.But radiotherapy there is side effect it is strong the shortcomings that.And The size of the side effect of radiotherapy is directly related to the dosage of radiation, but the calculating of radiological dose but can only be with patient's state of an illness The order of severity determine, and the impression of patient can not be considered.Therefore patient often exists all kinds of simultaneously when receiving radiotherapy Side effect so that the experience extreme difference of patient.
At present, magnetic therapy combined radiotherapy is a kind of relatively advanced radiotherapy pattern, the pattern by magnetic therapy and the combination of radiotherapy, During so that the biological effect of magnetic therapy combined radiotherapy treatment tumour is identical with the biological effect of independent radiotherapy, in magnetic therapy combined radiotherapy Radiotherapy dosimetry when Radiotherapy dosimetry is than independent radiotherapy is small, therefore can effectively reduce as the side effect caused by radiotherapy.But mesh The calculating of Radiotherapy dosimetry during preceding magnetic therapy combined radiotherapy is constantly in the state that artificial experience calculates so that during magnetic therapy combined radiotherapy Radiotherapy dosimetry calculate can not scientific algorithm.
The content of the invention
It is an object of the invention to provide one kind can accurately calculate patient's radiotherapy metering, and can automatically generate treatment The novel radiation treatment treatment planning systems of plan.
This novel radiation treatment treatment planning systems provided by the invention, including radiotherapy planning module, magnetic therapy schedule module, magnetic Treat combined radiotherapy computing module and output module;Radiotherapy in the treatment is each in space when radiotherapy planning module is used to obtain independent radiotherapy The Radiotherapy dosimetry of position is simultaneously input to magnetic therapy combined radiotherapy computing module;When magnetic therapy schedule module is used to calculate magnetic therapy combined radiotherapy Magnetotherapy treatment each position in space magnetic therapy dosage and be input to magnetic therapy combined radiotherapy computing module;Magnetic therapy combined radiotherapy calculates Module is for according to radiotherapy in the treatment during independent radiotherapy, in the Radiotherapy dosimetry and magnetic therapy combined radiotherapy of each position in space, magnetic therapy to be controlled Treat the magnetic therapy dosage in each position in space, radiotherapy of the radiotherapy in the treatment in each position in space when magnetic therapy combined radiotherapy is calculated Dosage simultaneously uploads output module;Output module is according to the Radiotherapy dosimetry and magnetic therapy dosage of each position of magnetic therapy combined radiotherapy time space Export final treatment plan.
During described calculating magnetic therapy combined radiotherapy magnetotherapy treatment each position in space magnetic therapy dosage, specially according to magnetic Magnetic therapy dosage of the magnetotherapy treatment in each position in space when the parameter for the treatment of equipment calculates magnetic therapy combined radiotherapy.
Described radiotherapy in the treatment when magnetic therapy combined radiotherapy is calculated each position in space Radiotherapy dosimetry, be with independent Radiotherapy in the treatment is when the Radiotherapy dosimetry of each position in space is to biological effect caused by organism and magnetic therapy combined radiotherapy during radiotherapy It is principle that Radiotherapy dosimetry, which acts on same organism and produces identical biological effect, radiotherapy in the treatment when calculating magnetic therapy combined radiotherapy Radiotherapy dosimetry in each position in space.
Described radiotherapy in the treatment when magnetic therapy combined radiotherapy is calculated specially is adopted in the Radiotherapy dosimetry of each position in space Radiotherapy dosimetry is calculated with following steps:
S1. organism experiment is carried out in advance, and it is D to obtain magnetic therapy dosageBWhen, the Radiotherapy dosimetry modifying factor of magnetic therapy combined radiotherapy Sub- C;Specially modifying factor C is obtained using following steps:
A. independent Radiotherapy dosimetry D is obtainedrayBiological effect on living organism;
B. obtain in magnetic therapy dosage DBWhen, Radiotherapy dosimetry D during magnetic therapy combined radiotherapyRAct on the organism described in step S1 On biological effect;
C. when the biological effect described in step S1 and step S2 is equal, magnetic therapy combined radiotherapy is calculated using equation below Dosage modifying factor C:
C=Dray/DR
S2. when generating treatment plan, measured according to the magnetic therapy at each position on living organism, according to magnetic therapy combined radiotherapy Dosage modifying factor C each positions on living organism when magnetic therapy combined radiotherapy is calculated Radiotherapy dosimetry.
This novel radiation treatment treatment planning systems provided by the invention, it is identical for criterion with the biological effect of living organism, The system for the treatment of plan of magnetic therapy combined radiotherapy can be accurately generated by providing one;The present invention being capable of automatic and accurate calculating patient Radiotherapy measure and automatically generate treatment plan, simple and convenient, science is directly perceived, and effectively medical worker can be instructed.
Brief description of the drawings
Fig. 1 is the functional block diagram of the present invention.
Embodiment
It is as shown in Figure 1 the functional block diagram of the present invention:This novel radiation treatment treatment planning systems provided by the invention, bag Include radiotherapy planning module, magnetic therapy schedule module, magnetic therapy combined radiotherapy computing module and output module.
Radiotherapy dosimetry and input of the radiotherapy in the treatment in each position in space when radiotherapy planning module is used to obtain independent radiotherapy To magnetic therapy combined radiotherapy computing module;The Radiotherapy dosimetry of independent radiotherapy can using it is existing it is conventional by the way of obtain, such as:Medical courses in general CMS radiotherapy plannings system, Monaco radiotherapy planning systems up to company, the Pinnacle radiotherapy planning systems of PHILIPS Co., Eclipse radiotherapy planning systems of Varian Associates, Inc. (US) 611 Hansen Way, Palo Alto, California 94303, U.S.A. etc..
Magnetic therapy schedule module be used for magnetotherapy treatment when calculating magnetic therapy combined radiotherapy each position in space magnetic therapy dosage simultaneously It is input to magnetic therapy combined radiotherapy computing module;The acquisition of magnetic therapy metering, mainly calculates magnetic therapy according to the parameter of device for magnetotherapy Magnetic therapy dosage D of the magnetotherapy treatment in each position in space during combined radiotherapyB,xi,yi,zi
Magnetic therapy combined radiotherapy computing module is used for according to radiotherapeutic agents of radiotherapy in the treatment during independent radiotherapy in each position in space Amount and during magnetic therapy combined radiotherapy magnetotherapy treatment each position in space magnetic therapy dosage, with radiotherapy in the treatment during independent radiotherapy in space Radiotherapy dosimetry was acted on all one's life when the Radiotherapy dosimetry of each position is to biological effect caused by organism and magnetic therapy combined radiotherapy Object and to produce identical biological effect be principle, radiotherapy in the treatment is in each position in space when magnetic therapy combined radiotherapy is calculated Radiotherapy dosimetry simultaneously uploads output module;Specially Radiotherapy dosimetry is calculated using following steps:
S1. substantial amounts of organism experiment is carried out in advance, and it is D to obtain magnetic therapy dosageBWhen, the Radiotherapy dosimetry of magnetic therapy combined radiotherapy Modifying factor C;Specially modifying factor C is obtained using following steps:
A. independent Radiotherapy dosimetry D is obtainedrayBiological effect on living organism;
B. obtain in magnetic therapy dosage DBWhen, Radiotherapy dosimetry D during magnetic therapy combined radiotherapyRAct on the organism described in step S1 On biological effect;
C. when the biological effect described in step S1 and step S2 is equal, magnetic therapy combined radiotherapy is calculated using equation below Dosage modifying factor C:
C=Dray/DR
Above-mentioned modifying factor, can be according to DBIt is of different sizes, calculate each different magnetic therapy dosage DBWhen, its magnetic therapy The dosage modifying factor C of combined radiotherapy, so as to obtain the dosage modifying factor C of magnetic therapy combined radiotherapy correction chart, so as to Directly used in the later stage;
S2. when generating treatment plan, measured according to the magnetic therapy at each position on living organism, according to magnetic therapy combined radiotherapy Dosage modifying factor C each positions on living organism when magnetic therapy combined radiotherapy is calculated Radiotherapy dosimetry, as Dxi,yi,zi =C*DRxi,yi,zi, D in formulaxi,yi,ziFor magnetic therapy combined radiotherapy when living organism on each position Radiotherapy dosimetry, DR,xi,yi,ziFor During magnetic therapy combined radiotherapy on living organism each position magnetic therapy dosage.
Output module exports finally according to the Radiotherapy dosimetry and magnetic therapy dosage of each position of magnetic therapy combined radiotherapy time space Treatment plan.
This novel radiation treatment treatment planning systems provided by the invention, after final treatment plan is exported, carried to doctor The optimal treatment plan being calculated for a system, and to be only doctor work out final therapeutic scheme to the treatment plan carries For a reference.

Claims (4)

1. a kind of novel radiation treatment treatment planning systems, it is characterised in that including radiotherapy planning module, magnetic therapy schedule module, magnetic therapy connection Close radiotherapy computing module and output module;Radiotherapy in the treatment is in each position in space when radiotherapy planning module is used to obtain independent radiotherapy Radiotherapy dosimetry and be input to magnetic therapy combined radiotherapy computing module;Magnetic therapy when magnetic therapy schedule module is used to calculate magnetic therapy combined radiotherapy Treat the magnetic therapy dosage in each position in space and be input to magnetic therapy combined radiotherapy computing module;Magnetic therapy combined radiotherapy computing module For according to radiotherapy in the treatment during independent radiotherapy, in the Radiotherapy dosimetry and magnetic therapy combined radiotherapy of each position in space, magnetotherapy treatment to exist The magnetic therapy dosage of each position in space, Radiotherapy dosimetry of the radiotherapy in the treatment in each position in space when magnetic therapy combined radiotherapy is calculated And upload output module;Output module exports according to the Radiotherapy dosimetry and magnetic therapy dosage of each position of magnetic therapy combined radiotherapy time space Final treatment plan.
2. novel radiation treatment treatment planning systems according to claim 1, it is characterised in that described calculating magnetic therapy, which is combined, puts Magnetotherapy treatment is in the magnetic therapy dosage of each position in space during treatment, specially calculates magnetic therapy according to the parameter of device for magnetotherapy and combines and puts Magnetic therapy dosage of the magnetotherapy treatment in each position in space during treatment.
3. novel radiation treatment treatment planning systems according to claim 2, it is characterised in that described is calculated magnetic therapy connection Close radiotherapy when radiotherapy in the treatment each position in space Radiotherapy dosimetry, be with radiotherapy in the treatment during independent radiotherapy in each position in space Radiotherapy dosimetry same organism is acted on Radiotherapy dosimetry during magnetic therapy combined radiotherapy to biological effect caused by organism and produced Raw identical biological effect is principle, Radiotherapy dosimetry of the radiotherapy in the treatment in each position in space when calculating magnetic therapy combined radiotherapy.
4. novel radiation treatment treatment planning systems according to claim 3, it is characterised in that described is calculated magnetic therapy connection Close radiotherapy when radiotherapy in the treatment each position in space Radiotherapy dosimetry, specially using following steps calculate Radiotherapy dosimetry:
S1. organism experiment is carried out in advance, and it is D to obtain magnetic therapy dosageBWhen, the Radiotherapy dosimetry modifying factor C of magnetic therapy combined radiotherapy; Specially modifying factor C is obtained using following steps:
A. independent Radiotherapy dosimetry D is obtainedrayBiological effect on living organism;
B. obtain in magnetic therapy dosage DBWhen, Radiotherapy dosimetry D during magnetic therapy combined radiotherapyRAct on the organism described in step S1 Biological effect;
C. when the biological effect described in step S1 and step S2 is equal, the dosage of magnetic therapy combined radiotherapy is calculated using equation below Modifying factor C:
C=Dray/DR
S2. when generating treatment plan, measured according to the magnetic therapy at each position on living organism, according to the agent of magnetic therapy combined radiotherapy Measure the Radiotherapy dosimetry at each position on living organism when magnetic therapy combined radiotherapy is calculated in modifying factor C.
CN201710618443.0A 2017-07-26 2017-07-26 Novel radiotherapy treatment planning system Expired - Fee Related CN107412963B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110368605A (en) * 2019-08-19 2019-10-25 中北大学 A kind of adaptive radiation therapy system of biological effect guidance

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Publication number Priority date Publication date Assignee Title
CN102247659A (en) * 2011-04-12 2011-11-23 天津大学 System for promoting bystander effect of radiotherapy by utilizing low-intensity ultrasound
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CN205339861U (en) * 2016-01-12 2016-06-29 王静 Department of neurology electromagnetic therapy apparatus

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102247659A (en) * 2011-04-12 2011-11-23 天津大学 System for promoting bystander effect of radiotherapy by utilizing low-intensity ultrasound
CN104606797A (en) * 2015-02-10 2015-05-13 霍玉青 Tumor in-vivo radiotherapy device
CN205339861U (en) * 2016-01-12 2016-06-29 王静 Department of neurology electromagnetic therapy apparatus

Non-Patent Citations (1)

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Title
谭厚生: "放疗合并磁疗治疗一例滑膜肉瘤报告", 《四川肿瘤防治》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110368605A (en) * 2019-08-19 2019-10-25 中北大学 A kind of adaptive radiation therapy system of biological effect guidance
CN110368605B (en) * 2019-08-19 2020-12-01 中北大学 Biological effect guided self-adaptive radiotherapy system

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