WO2023273636A1 - 防晒修护组合物及其制备方法 - Google Patents
防晒修护组合物及其制备方法 Download PDFInfo
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- WO2023273636A1 WO2023273636A1 PCT/CN2022/092698 CN2022092698W WO2023273636A1 WO 2023273636 A1 WO2023273636 A1 WO 2023273636A1 CN 2022092698 W CN2022092698 W CN 2022092698W WO 2023273636 A1 WO2023273636 A1 WO 2023273636A1
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Definitions
- the invention belongs to the technical field of daily cosmetics, and in particular relates to a sunscreen repairing composition and a preparation method of the sunscreen repairing composition.
- Solar radiation can be simply divided into visible light and invisible light.
- infrared radiation which is often overlooked, accounts for the sunlight reaching the skin. More than 50% of the total amount is far higher than 7% of the total amount of sunlight that ultraviolet rays reach the skin.
- Infrared IRA can directly penetrate the entire dermis, causing collagen damage and loss, causing skin aging.
- the environment that human beings depend on is inseparable from the influence of visible light.
- the 400-500nm blue light band has the highest energy. It exists not only in sunlight, but also in the background light source of digital products in large quantities. It is next to ultraviolet rays in a broad spectrum. The strong penetrating power to the skin will accelerate the aging of the skin.
- sun protection should not be limited to resisting ultraviolet rays. Consumers are more pursuing comprehensive light protection, reducing the increase of free radicals, preventing and alleviating photoaging and other multi-functional sun protection product. Therefore, in addition to increasing the protection ability of UVA and UVB segments in the formulation design of sunscreen products, it is also necessary to pay attention to other skin problems caused by light radiation and urban pollution. At the same time, adding free radical scavengers to sunscreen products can not only enhance the protection of sunscreens function while effectively preventing photoaging.
- sunscreen products are limited to simple ultraviolet protection, ignoring the various skin care functions related to photoprotection that cause skin photoaging mechanisms.
- sunscreen products are no longer a combination of simple sunscreen agents, and consumers are still looking for multifunctional care products that better meet their demands.
- the protective ability of sunscreen products depends not only on their own sunscreen performance and application amount, but also on the loss of sunscreen ingredients caused by factors such as sweat, water immersion, and clothing friction. Therefore, adding water-resistant polymers can significantly improve the sunscreen ability of the product , reduce the stickiness of sunscreen and oil, and bring a pleasant skin experience.
- a more comprehensive sunscreen repair formula should take into account the following aspects: 1. Full-band light protection (UVA, UVB, HEV, IRA); 2. The waterproof and anti-perspiration effect of sunscreen products to enhance sunscreen performance; 3. Help the skin Resists external pollution and protects the skin barrier from damage. 4. Add bioactive raw materials to enhance the skin's defense ability, reduce the damage of light radiation to the skin, powerfully resist oxidation, and prevent photoaging.
- the present invention provides a sunscreen repairing composition, which can enhance the skin's ability to resist external stimuli while providing full-band light protection.
- the first purpose of the present invention is to provide a sunscreen repair composition, which solves the technical problem that existing sunscreen products cannot achieve comprehensive sunscreen repair.
- the second object of the present invention is to provide a method for preparing a sunscreen repairing composition.
- a sunscreen repairing composition comprising a sunscreen repairing component, based on the total amount of the sunscreen repairing composition, the sunscreen repairing component includes the following components in mass percentage: sunscreen composition 0.05%-50%;
- the sunscreen composition is composed of isoamyl methoxycinnamate, bis-ethylhexyloxyphenol methoxyphenyl triazine wrapped in silica, diethylamino hydroxybenzoyl hexyl benzoate, phenylbenzimidazole Sulfonic acid and methylene bis-benzotriazolyltetramethylbutylphenol.
- the sunscreen composition isoamyl methoxycinnamate, silica-coated bis-ethylhexyloxyphenol methoxyphenyl triazine, diethylamino hydroxybenzoyl hexyl benzoate, benzene
- the mass percentages of phenylbenzimidazole sulfonic acid and methylene bis-benzotriazolyl tetramethylbutylphenol to the total amount of the sunscreen repairing composition are 0.01%-10%, 0.01%-10%, and 0.01% respectively -10%, 0.01%-10%, 0.01%-10%.
- the protection band of phenylbenzimidazole sulfonic acid is 280-340nm
- the protection band of isoamyl methoxycinnamate is 280-340nm
- the protection band of triazine is 280-400nm
- the protection band of diethylamino hydroxybenzoyl hexyl benzoate is 280-430nm
- the protection band of methylene bis-benzotriazolyl tetramethylbutylphenol is 280-900nm , covering the full-band protection of ultraviolet light, blue light, and infrared light.
- methylene bis-benzotriazolyl tetramethylbutylphenol is a water-soluble UVA, UVB, HEV, and IRA full-band sunscreen agent. It is the sunscreen agent with the longest protection band in current sunscreen technology. At the same time, it immediately blocks Infrared performance makes it have excellent sunlight heat resistance effect. Sunshine heat resistance refers to the skin or object surface. After being exposed to light, the surface temperature rises steadily. After adding specific substances, the temperature rises slowly or remains at a low level.
- phenylbenzimidazole sulfonic acid and methylene bis-benzotriazolyl tetramethylbutylphenol are water-soluble sunscreens, isoamyl methoxycinnamate, diethylaminohydroxyl Benzoyl hexyl benzoate is an oil-soluble sunscreen agent, bis-ethylhexyloxyphenol methoxyphenyl triazine wrapped in silica, can be evenly dispersed in water and oil two phases. Through the combination of water and oil two-phase sunscreen, it is easier to form a dense protective film, and it is more comprehensive to protect against ultraviolet and visible light damage.
- the sunscreen composition is highly efficient, stable, mild and low-sensitivity, and can still maintain strong sunscreen performance for a long time under ultraviolet radiation, and at the same time, it hardly penetrates the skin, and has very high mildness performance.
- the silica-wrapped bis-ethylhexyloxyphenol methoxyphenyl triazine is silicon dioxide-wrapped bis-ethylhexyloxyphenol methoxyphenyl triazine.
- silica-wrapped bis-ethylhexyloxyphenol methoxyphenyl triazine is obtained by wrapping the bis-ethylhexyloxyphenol methoxyphenyl triazine with silicon dioxide, Then obtained by surface modification.
- the sunscreen agent bis-ethylhexyloxyphenol methoxyphenyl triazine is wrapped in silica, which can reduce the sunscreen while assisting the stability of the sunscreen It improves the mildness through the skin absorption of the sunscreen, has both light-scattering and light-absorbing effects in optical protection, and provides a refreshing skin feeling. It is a future type of sunscreen.
- silica coating such a shell also has a light-quenching effect.
- the sunscreen repairing component also includes a defense factor composition
- the defense factor composition is composed of the following mass percentage components based on the total amount of the sunscreen repairing composition: coffee agaricus seed extract 0.0001%-5% carnosine, 0.0001%-5% carnosine.
- the coffee seed extract is extracted from coffee seeds, and the coffee seeds are rich in active ingredient glycopeptide, which has a strong absorption effect in the blue light region and can also improve the ultraviolet protection performance.
- the overall protective performance of the formula is enhanced, and it has the effects of soothing irritation, scavenging free radicals, and anti-aging.
- the extract of Coffea arabica seed is obtained by subcritical water extraction method.
- the physical and chemical characteristics of subcritical water are quite different from those of water at normal temperature and pressure.
- the polarity of water at normal temperature and pressure is strong, and in the subcritical state, as the temperature rises, the hydrogen bonds of the subcritical water are opened or weakened, so that the polarity of the water can be controlled by controlling the temperature and pressure of the subcritical water.
- the properties can be changed in a wide range, so as to realize the continuous extraction of active ingredients in natural products from water-soluble components to fat-soluble components, and can achieve selective extraction.
- carnosine is an amino acid polypeptide, which exists in human muscle itself, has super anti-aging ability, and helps the human body to resist aging. More than half of the energy of infrared IRA can reach human skin, and most of IRA can reach the dermis. IRA can decompose and destroy collagen and accelerate skin aging. Carnosine can significantly inhibit the production of metalloproteinase MMP-1 and inhibit the decomposition of collagen.
- the sunscreen repair component further includes a synergist, and the mass percentage of the synergist is 0.0001%-5% based on the total amount of the sunscreen repair composition.
- the synergist is poly C10-30 alkanol acrylate.
- Poly C10-30 alkanol acrylate is a film-forming synergist. Its EWG score is 1, which represents its green-friendly performance. It is suitable for the current trend of environmental protection and can be combined with sunscreen agents to effectively improve the uniformity of sunscreen films. and toughness, improve the water resistance of sunscreen ingredients.
- the poly C10-30 alkanol acrylate makes the sunscreen repair component of the present invention applied to daily chemical products, it can enhance the water resistance and friction resistance of W/O and O/W system products, and improve the durability of light protection.
- the sunscreen repair component also includes a bioactive composition
- the bioactive composition is composed of carbohydrate isomers, fullerene dispersion, vitamin C ethyl ether, anti-aging Composed of polluting algae extract and tetrahydromethyl pyrimidine carboxylic acid.
- the biologically active composition of the present invention can deeply lock water, enhance skin defense ability, super-strong anti-oxidation, and block urban pollutants while protecting light.
- sugar isomers, fullerene dispersion, vitamin C ethyl ether, anti-pollution algae extract and tetrahydromethyl pyrimidine carboxylic acid are used as a sunscreen repair composition
- the mass percentages in the total amount are 0.0001%-5%, 0.0001%-5%, 0.0001%-5%, 0.0001%-5%, and 0.0001%-5%.
- fullerene dispersion is an aqueous dispersion of fullerenes with a mass fraction of 0.02%.
- tetrahydromethylpyrimidine carboxylic acid has the ability to protect cells and enhance the skin's ability to resist UV light and dry weather, and is one of the ideal raw materials for sun protection and anti-aging.
- Adding anti-pollution algae extract to the skin can form an invisible protective film to protect the skin. At the same time, it has the effect of chelating heavy metals and protecting cells.
- the anti-pollution effect of the present invention can be realized .
- Fullerenes can scavenge free radicals through surface adsorption.
- fullerene plays the role of electron transmission in the process of scavenging free radicals, there is no consumption loss in the process, so it can exist stably on the surface of products and skin, and exert its antioxidant capacity for a long time. Because of this unique performance, it can achieve anti-aging, anti-oxidation, hair follicle repair, anti-acne, pore tightening, whitening, soothing and other effects.
- Sunlight irradiates the skin to produce a large number of free radicals, which are one of the main factors causing skin erythema.
- the present invention adds fullerenes to remove a large number of free radicals produced by sunlight, so that effective protection can be achieved from the cytology.
- Vitamin C ethyl ether is a new generation of stabilized vitamin C derivatives. It has hydrophilic and lipophilic properties. Vitamin C is often used as an antioxidant and has reducing properties. It can inhibit the oxidation of melanin intermediate dopaquinone into melanin, but it is very easy to oxidize , through conversion into derivatives, not only improves its stability, but also improves bioavailability. Sugar isomers, which can be closely combined with water, can play a short-term and long-term moisturizing effect, and strengthen the skin barrier for a long time, especially for dryness and water loss that are often encountered in sun exposure.
- a preparation method of a sunscreen repairing composition comprising the following steps:
- oil phase sunscreen repair composition (1) adding an oil phase solvent to the isoamyl methoxycinnamate, diethylamino hydroxybenzoyl hexyl benzoate and poly C10-30 alkanol acrylate, heating and dissolving to obtain an oil phase sunscreen repair composition;
- step (3) Mix the oil phase of step (1) with the water phase of step (2), heat and homogeneously emulsify evenly, cool down, then add bis-ethylhexyloxyphenol methoxyphenyl triazine wrapped in silica, add tetrahydro Methylpyrimidine carboxylic acid, coffee seed extract, carnosine, sugar isomers, anti-pollution algae extract, fullerene dispersion, vitamin C ethyl ether are stirred and dispersed evenly to obtain a sunscreen repair composition .
- the oil phase part and the water phase part involved in the present invention are added in different process stages according to the characteristics of the formula in the cosmetic formulation, so that the sunscreen repairing composition has better uniformity and dispersion performance.
- the heating temperature in step (1) is 80-90°C.
- the lye is arginine in the step (2).
- step (3) the homogeneous temperature is 75-85° C., and the temperature is lowered to below 50° C.
- the homogenization temperature is 80°C.
- the present invention has the following beneficial effects:
- the sunscreen composition in the sunscreen repair component of the present invention covers the full-band protection of ultraviolet light, blue light, and infrared light, and can form a broad-spectrum sunscreen net on the skin surface to effectively block the damage of light radiation to the skin.
- the sunscreen composition of the present invention adopts oil-soluble sunscreen agent and water-soluble sunscreen agent, which can spread the sunscreen film evenly on the skin without sunscreen loopholes, and is suitable for various sunscreen products. It is used in cosmetics to make the formula mild, low irritation, and has extremely high light stability. It is widely used in W/O and O/W system products, and can provide certain hydrophobicity for O/W formula systems and enhance W/O The water and sweat resistance of the system.
- the bioactive composition added to the sunscreen repair component of the present invention can help the skin resist external pollution, enhance skin defense ability, powerful anti-oxidation, comprehensive photoprotection and prevent skin photoaging at the same time.
- the sunscreen repair component of the present invention has the characteristics of waterproof, heat resistance, and friction resistance, and can achieve high sun protection value, mild formula, moisturizing and water locking, and has good water and sweat resistance sunscreen products, which are more suitable for Asian people , has broad market prospects.
- Fig. 1 is the broad-spectrum protective net schematic diagram of each component of sunscreen composition in sunscreen repair component (Solarex-X) among the present invention
- Fig. 2 is the absorption broad spectrum of defensive factor coffee apricot seed extract in the present invention
- Fig. 3 is the figure of sun protection value of light of different bands of the sun protection maintenance composition of embodiment 1 of the present invention.
- Fig. 4 is the transmittance diagram of light in different wavelength bands of the sunscreen repairing composition according to Example 2 of the present invention.
- Fig. 5 is the figure of the sun protection value of light of different bands of the sun protection repairing composition of Example 2 of the present invention.
- Fig. 6 is a diagram of the sun protection value of light in different wavelength bands of the sun protection repair composition of the present invention.
- a sunscreen repairing composition (broad-spectrum sunscreen lotion SPF30+, PA+++), including a sunscreen repairing component (Solarex-X), the sunscreen repairing component is based on the total amount of the sunscreen repairing composition, composed of the following mass percentages: grouped into:
- a sunscreen repairing composition (broad-spectrum sunscreen lotion SPF50+, PA+++), including a sunscreen repairing component (Solarex-X), the sunscreen repairing component is based on the total amount of the sunscreen repairing composition, composed of the following mass percentages: grouped into:
- a sunscreen repairing composition (broad-spectrum sunscreen lotion SPF30+, PA+++), including a sunscreen repairing component (Solarex-X), differs from Example 1 in that the sunscreen repairing component is based on the sunscreen repairing composition Meter, composed of the following components in mass percentage:
- a sunscreen repairing composition (broad-spectrum sunscreen lotion SPF50+, PA+++), including a sunscreen repairing component (Solarex-X), differs from Example 2 in that the sunscreen repairing component is based on the sunscreen repairing composition Meter, composed of the following components in mass percentage:
- a sunscreen lotion which differs from Example 1 in that it does not contain sunscreen repair components, and the rest of the ingredients are the same as in Example 1.
- FIG 1 The schematic diagram of the broad-spectrum protective net of each component of the sunscreen composition (Solarex-X) in the present invention is shown in Figure 1; the defense factor coffee seed extract in the formula of the present invention absorbs a broad spectrum, as shown in the figure 2; respectively detect the sun protection value of the different band light of the sunscreen repairing composition prepared by Example 1, Example 2 and comparative example, and detect the transmittance of the different band light of the sunscreen repairing composition prepared by Example 2, the result See Figure 3, Figure 5, Figure 6, and Figure 4 respectively. (Testing instrument, UV2000S sun protection index tester)
- the sunscreen repair component (Solarex-X) is suitable for the development of various sunscreen products, including regular SPF30+ sunscreen and SPF50+ high sunscreen products.
- Example 1 showed higher sunscreen value, and obtained effective protection in the blue light band.
- Example 2 has a blue light transmittance of 0.51, which proves that almost half of the blue light is protected.
Abstract
本发明提供了一种防晒修护组合物，包括防晒修护组分，以防晒修护组合物总量计，所述防晒修护组分包括以下质量百分比的组分：防晒剂组合物0.05％-50％；所述防晒剂组合物由甲氧基肉桂酸异戊酯、硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪、二乙氨基羟苯甲酰基苯甲酸己酯、苯基苯并咪唑磺酸和亚甲基双-苯并三唑基四甲基丁基酚组成。本发明防晒修护组分中防晒剂组合物涵盖了紫外光、蓝光、红外光的全波段防护，可在皮肤表面组建广谱防晒网，有效地阻断光辐射对肌肤的损伤。
Description
本发明属于日用化妆品技术领域，具体涉及一种防晒修护组合物，还涉及该防晒修护组合物的制备方法。
地球环境持续变化，最引人关注的话题之一是全球气候变暖和人类环境污染导致的温室效应，可能导致臭氧层的破坏形成巨大空洞，进入地球的紫外线强度会日益增加。当人类长时间、大剂量受到紫外线的照射时，会对皮肤乃至机体造成很大的损伤，轻则引起皮肤浅层的脱皮红肿，紫外线的继续穿透会导致真皮层的细胞组织和胶原蛋白损伤，大量黑色素细胞生成，出现皮肤过早衰老和光老化，严重的可能会出现各类皮肤病，甚至皮肤癌等危及生命。
随着人类文明的进步，人们追求更健康的生活方式，户外活动的活跃性提高。世界卫生组织统计，有超过80％的大城市空气污染指数超标，如今更多的肌肤问题是由于暴露于城市污染的环境中，工业废气、机动车尾气以及生态环境导致的烟尘微粒的污染会破坏皮肤细胞，引发各类皮肤问题。
由于环境的污染引起的臭氧破坏会导致到达地表的太阳辐射增大，太阳辐射可简单地分为可见光和不可见光，不可见光中除了大众所熟知的紫外线辐射，常被忽视的红外线占到达皮肤阳光总量的50％以上，远高于紫外线到达皮肤阳光总量的7％，红外线IRA可直接穿透整个真皮层，致使胶原蛋白破坏和流失，引起皮肤衰老。同时，人类赖以生存的环境离不开可见光的影响，其中以400-500nm蓝光波段能量最高，它不仅存在于太阳光中，也大量存在于数码产品的背景光源，在广谱中紧邻紫外线，对皮肤的强穿透力会加速肌肤的老化。
随着人们对于皮肤护理的需求日益增长，防晒不应仅局限于抵抗紫外线的侵袭，消费者更多地追求全面的光防护，减少自由基的增加，预防和减轻光老化等多功能性的防晒产品。因此，防晒产品配方设计中除了增加UVA、UVB段的防护能力外，还需要关注其他光辐射、城市污染引发的皮肤问题，同时在防晒产品中添加自由基清除剂，不仅能增强防晒剂的保护功能，同时有效地防止光老化。
市面上常见的传统防晒产品大多局限在简单的紫外线防护领域，忽略引起皮肤光老化机制的多样、与光防护相关的护肤功能。随着大众对皮肤护理需求的日益增加，防晒产品不再是简单的防晒剂的组合，消费者仍在寻求更符合其诉求的多功能性护理产品。
使用防晒产品后，日常的光辐射不可避免的会对皮肤产生灼热，引起刺激和脱水，在给皮肤提供全面光防护的同时，添加保湿、修护、抗氧化成分是必要的，可通过增强皮肤本身抵御光辐射的能力，减少自由基的产生，延缓光老化，发挥辅助协同作用。同时，如今被证实的城市污染中细小的污染颗粒能够穿透皮肤，损伤皮肤细胞，添加抗污染活性物在表皮形成隐形的保护膜，避免污染物渗透进入皮肤。
防晒产品的防护能力不仅取决于其本身的防晒性能和施加量，也取决于汗水、水浸、衣物摩擦等因素造成防晒成分的损失，因此添加具有抗水性能聚合物可以明显提升产品的防晒能力，减少防晒剂和油脂的黏腻感，带来愉悦的肤感体验。
更全面的防晒修护配方应该考虑到以下几个方面：1、全波段的光防护(UVA、UVB、HEV、IRA)；2、防晒产品的防水抗汗功效，加强防晒性能；3、帮助肌 肤抵御外界的污染，保护肌肤屏障损伤。4、添加生物活性原料，增强肌肤防御能力，降低光辐射对肌肤的损伤，强效抗氧化，防止光老化。
基于此，本发明提供一款防晒修护组合物，进行全波段光防护的同时增强肌肤抵御外界刺激的能力。
发明内容
本发明第一目的在于提供一种防晒修护组合物，解决的技术问题是现有的防晒用品无法实现全面防晒修护的不足。
本发明第二目的在于提供一种防晒修护组合物的制备方法。
本发明的目的是通过以下技术方案来实现的：
一种防晒修护组合物，包括防晒修护组分，以防晒修护组合物总量计，所述防晒修护组分包括以下质量百分比的组分：防晒剂组合物0.05％-50％；所述防晒剂组合物由甲氧基肉桂酸异戊酯、硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪、二乙氨基羟苯甲酰基苯甲酸己酯、苯基苯并咪唑磺酸和亚甲基双-苯并三唑基四甲基丁基酚组成。
进一步地，所述防晒剂组合物中，甲氧基肉桂酸异戊酯、硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪、二乙氨基羟苯甲酰基苯甲酸己酯、苯基苯并咪唑磺酸和亚甲基双-苯并三唑基四甲基丁基酚占防晒修护组合物总量的质量百分比分别为0.01％-10％，0.01％-10％，0.01％-10％，0.01％-10％，0.01％-10％。
本发明防晒剂组合物中，苯基苯并咪唑磺酸的防护波段在280～340nm，甲氧基肉桂酸异戊酯的防护波段在280～340nm，双-乙基己氧苯酚甲氧苯基三嗪的防护波段在280～400nm，二乙氨基羟苯甲酰基苯甲酸己酯的防护波段在280～430nm，亚甲基双-苯并三唑基四甲基丁基酚防护波段280～900nm，涵盖了 紫外光和蓝光、红外光的全波段防护。其中亚甲基双-苯并三唑基四甲基丁基酚是水溶性UVA、UVB、HEV、IRA全波段防晒剂，是目前防晒技术上防护波段最长的防晒剂，同时，其即时阻挡红外的性能，使其具有优异的日照抗热效果。日照抗热，指的是皮肤或物体表面，受光照后本来表面温度是稳定上升，加入特定物质后温度上升幅度低，或者维持在较低水平。
本发明防晒剂组合物中，苯基苯并咪唑磺酸和亚甲基双-苯并三唑基四甲基丁基酚是水溶防晒剂，甲氧基肉桂酸异戊酯，二乙氨基羟苯甲酰基苯甲酸己酯，是油溶防晒剂，硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪，能均匀分散于水油两相。通过水油两相防晒剂搭配，更易于形成致密的防护膜，更全方位防护紫外及可见光伤害。该防晒组合物高效稳定、温和低敏，在紫外照射下，依然能长时间保持强效防晒性能，同时几乎不会渗透皮肤，具有很高的温和性能。
本发明中，所述硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪是二氧化硅包裹的双-乙基己氧苯酚甲氧苯基三嗪。
进一步地，所述二氧化硅包裹的双-乙基己氧苯酚甲氧苯基三嗪，通过以下方式获得：用二氧化硅对双-乙基己氧苯酚甲氧苯基三嗪进行包裹，然后经表面改性得到。
硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪通过上述工艺将防晒剂双-乙基己氧苯酚甲氧苯基三嗪包裹在硅石中，在辅助防晒剂稳定的同时，降低防晒剂的皮肤吸收而提高温和性，在光学防护上同时兼具光散射和光吸收的效果更强效，并提供清爽肤感，是未来型的防晒剂形式。在技术上，硅石包裹这样的外壳还具有光淬灭的效果。
本发明可以做以下改进，所述防晒修护组分还包括防御因子组合物，所述防御因子组合物由以防晒修护组合物总量计的以下质量百分比组分组成：小果咖啡籽提取物0.0001％-5％，肌肽0.0001％-5％。
本发明防晒修护组分中，小果咖啡籽提取物由咖啡籽提取而来，咖啡籽中富含活性成分糖肽，在蓝光区域具有很强的吸收作用，同时还能提升紫外防护性能。通过有效的蓝光防护，与防晒剂组合物配合，增强了配方的整体防护性能，起到舒缓刺激、清除自由基、抗衰老等功效。
进一步地，小果咖啡籽提取物通过亚临界水萃取方法获得。亚临界水的物理、化学特性与常温常压下的水在性质上有较大差别。常温常压下水的极性较强，亚临界状态下，随着温度的升高，亚临界水的氢键被打开或减弱，这样就可以通过控制亚临界水的温度和压力，使水的极性在较大范围内变化，从而实现天然产物中有效成分从水溶性成分到脂溶性成分的连续提取，并可实现选择性提取。
本发明防晒修护组分中，肌肽是一种氨基酸多肽，本身就存在人体肌肉中，具有超强的抗衰老能力，帮助人体对抗老化。红外线IRA超过一半的能量能抵达人类肌肤，而大部分的IRA能抵达真皮层，IRA可以分解和破坏胶原蛋白，加速皮肤衰老。肌肽能显著抑制金属蛋白酶MMP-1的产生，抑制胶原蛋白的分解。
本发明可以做以下改进，所述防晒修护组分还包括增效剂，所述增效剂以防晒修护组合物总量计的质量百分比为0.0001％-5％。
进一步地，所述增效剂为聚C10-30烷醇丙烯酸酯。聚C10-30烷醇丙烯酸酯是一种成膜增效剂，其EWG分数为1，代表其绿色友好的性能，适合当下环 保潮流趋势，且能与防晒剂结合，有效提升防晒膜的均匀性和韧性，提高防晒成分的抗水能力。聚C10-30烷醇丙烯酸酯使本发明防晒修护组分应用到日化用品中后，能够增强W/O和O/W体系产品的抗水、耐摩擦性能，提升光防护持久性。
本发明可以进一步做以下改进，所述防晒修护组分还包括生物活性组合物，所述生物活性组合物由糖类同分异构体、富勒烯分散液、维C乙基醚、抗污染藻提取物和四氢甲基嘧啶羧酸组成。本发明中生物活性组合物能够深层锁水，增强肌肤防御能力，超强抗氧化，在光防护的同时阻隔城市污染物。
进一步地，所述生物活性组合物中，糖类同分异构体、富勒烯分散液、维C乙基醚、抗污染藻提取物和四氢甲基嘧啶羧酸以防晒修护组合物总量计的质量百分比分别为0.0001％-5％，0.0001％-5％，0.0001％-5％，0.0001％-5％，0.0001％-5％。
进一步地，所述富勒烯分散液为质量分数为0.02％富勒烯水分散液。
本发明生物活性组合物中，四氢甲基嘧啶羧酸具有保护细胞、增强皮肤抵抗UV光和干燥气侯的能力，是防晒抗老化的理想原料之一。加入抗污染藻提取物应用于皮肤上，能形成一张隐形的防护膜保护皮肤，同时，它具有螯合重金属，保护细胞的功效，作为亲肤性的活性成分，实现本发明的抗污染效果。富勒烯能通过表面吸附，清除自由基。由于富勒烯在清除自由基的过程起到的是电子传输的作用，过程中没有消耗损失，因此可以在产品及皮肤表面上稳定存在,持久发挥抗氧化的能力。因为这种独特的性能，它能实现抗衰老、抗氧化、修护毛囊、抗痘、紧致毛孔、美白、舒缓等功效。日光照射皮肤产生大量的自由基，这些自由基是引起皮肤红斑的主要因素之一，本发明加入富勒烯，清除 日光产生的大量自由基，从而可以从细胞学上做到有效防护。维C乙基醚，是新一代稳定化维生素C衍生物，具有亲水亲油性质，维生素C常用作抗氧化剂，具有还原性，能抑制黑色素中间体多巴醌氧化成黑色素，但非常容易氧化，通过转化为衍生物，不但提高了其稳定性，同时提高生物利用度。糖类同分异构体，其能与水紧密结合，能起到短时和长效保湿的作用，持久强化皮肤屏障，特别针对日晒中经常碰到的干燥、水分流失等现象。
一种防晒修护组合物的制备方法，包括以下步骤：
(1)向甲氧基肉桂酸异戊酯、二乙氨基羟苯甲酰基苯甲酸己酯与聚C10-30烷醇丙烯酸酯中加入油相溶剂加热溶解，得到油相防晒修护组合物；
(2)用碱液将苯基苯并咪唑磺酸中和成盐，然后再加入亚甲基双-苯并三唑基四甲基丁基酚搅拌溶解，得到水相防晒修护组合物；
(3)将步骤(1)油相与步骤(2)水相进行混合，加热均质乳化均匀，降温，再加入硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪、加入四氢甲基嘧啶羧酸、小果咖啡籽提取物、肌肽、糖类同分异构体、抗污染藻提取物、富勒烯分散液、维C乙基醚搅拌分散均匀，得到防晒修护组合物。
本发明中所涉及的油相部分和水相部分在化妆品配方中，根据配方的特点分不同的工艺阶段加入，使得防晒修护组合物具有更好的均匀性和分散性能。
进一步地，步骤(1)加热温度为80-90℃。
步骤(2)中碱液为精氨酸。
步骤(3)中均质温度为75-85℃，降温为降至50℃以下。
优选地，均质温度为80℃。
与现有技术相比，本发明具有以下有益效果：
(1)本发明防晒修护组分中防晒剂组合物涵盖了紫外光、蓝光、红外光的全波段防护，可在皮肤表面组建广谱防晒网，有效地阻断光辐射对肌肤的损伤。
(2)本发明防晒剂组合物采用油溶性防晒剂和水溶性防晒剂，可令防晒膜在皮肤均匀铺展，无防晒漏洞，适用于各类防晒产品。用于化妆品中使配方温和，刺激性低，具有极高的光稳定性，广泛适用于W/O和O/W体系产品，可为O/W配方体系提供一定的疏水性，增强W/O体系的抗水抗汗性能。(3)本发明防晒修护组分添加的生物活性组合物能帮助肌肤抵御外界污染，增强肌肤防御能力，强效抗氧化，全面光防护的同时防止肌肤光老化。
(4)本发明防晒修护组分具有防水、抗热、耐摩擦的特点，可以做到高防晒值、配方温和、保湿锁水，有良好抗水抗汗的防晒产品，更适合于亚洲人群，具有广阔的市场前景。
图1为本发明中防晒修护组分(Solarex-X)中防晒剂组合物各组分的广谱防护网示意图；
图2为本发明中防御因子小果咖啡籽提取物吸收广谱；
图3为本发明实施例1防晒修护组合物不同波段光的防晒值图；
图4为本发明实施例2防晒修护组合物不同波段光的透过率图；
图5为本发明实施例2防晒修护组合物不同波段光的防晒值图；
图6为本发明对比例防晒修护组合物不同波段光的防晒值图。
以下结合具体的实施例对本发明作进一步的说明，以便本领域技术人员更好理解和实施本发明的技术方案。
实施例1
一种防晒修护组合物(广谱防晒乳液SPF30+，PA+++)，包括防晒修护组分(Solarex-X)，防晒修护组分以防晒修护组合物总量计，由以下质量百分比的组分组成：
还包括以防晒修护组合物总量计的以下质量百分比组分：
上述防晒修护组合物的制备方法，包括以下步骤：
(1)按配方量将甲氧基肉桂酸乙基己酯、二乙氨基羟苯甲酰基苯甲酸己酯、甲氧基肉桂酸异戊酯、水杨酸辛酯、月桂酸乙基己酯、乙基己基三嗪酮、聚C10-30烷醇丙烯酸酯、吐温60加入一合适容器，加热至85℃，搅拌溶解完全，得到油相；
(2)往一合适容器中加入总量5％的水，再按配方量加入苯基苯并咪唑磺酸，加入精氨酸中和(调节pH)，然后再加入亚甲基双-苯并三唑基四甲基丁基酚，搅拌均匀；往另一合适容器中加入剩余量的水、卡波姆、丙烯酰二甲基牛磺酸 铵/VP共聚物，搅拌混合均匀，加入EDTA二钠、1,3-丙二醇、透明质酸钠，搅拌混合均匀，加热至70℃；将两个容器中内容物混合搅拌均匀，得到水相；
(3)在适当剪切条件下，将油相加入水相中，80℃均质搅拌使其乳化完全，搅拌冷却到50℃以下，加入硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪、防腐剂和剩余活性成分，搅拌均匀，继续冷却到40℃以下，调配结束。
实施例2
一种防晒修护组合物(广谱防晒乳液SPF50+，PA+++)，包括防晒修护组分(Solarex-X)，防晒修护组分以防晒修护组合物总量计，由以下质量百分比的组分组成：
还包括以防晒修护组合物总量计的以下质量百分比组分：
实施例3
一种防晒修护组合物(广谱防晒乳液SPF30+，PA+++)，包括防晒修护组分(Solarex-X)，与实施例1不同之处在于，防晒修护组分以防晒修护组合物总量计，由以下质量百分比的组分组成：
实施例4
一种防晒修护组合物(广谱防晒乳液SPF50+，PA+++)，包括防晒修护组分(Solarex-X)，与实施例2不同之处在于，防晒修护组分以防晒修护组合物总量计，由以下质量百分比的组分组成：
对比例
一种防晒乳液，与实施例1不同之处在于，不含有防晒修护组分，其余成分与实施例1相同。
性能测试
本发明中防晒修护组分(Solarex-X)中防晒剂组合物各组分的广谱防护网示意图，见图1；本发明配方中防御因子小果咖啡籽提取物吸收广谱，见图2；分别检测实施例1、实施例2和对比例制备的防晒修护组合物的不同波段光的防晒值，以及检测实施例2制备的防晒修护组合物不同波段光的透过率，结果分别见图3、图5、图6、图4。(检测仪器，UV2000S防晒指数测试仪)
由图3-6可知，防晒修护组分(Solarex-X)适合于各种防晒产品开发，包括常规SPF30+防晒和SPF50+高防晒产品。与对比例未添加Solarex-X防晒修护组分的配方相比，实施例1表现出更高的防晒值，而且在蓝光波段得到有效防护。实施例2蓝光透过率为0.51，证明几乎一半的蓝光得到了防护。
以上实施实例对本发明不同的实施过程进行了详细的阐述，但是本发明的实施方式并不仅限于此，所属技术领域的普通技术人员依据本发明中公开的内容，均可实现本发明的目的，任何基于本发明构思基础上做出的改进和变形均落入本发明的保护范围之内，具体保护范围以权利要求书记载的为准。
Claims (10)
- 一种防晒修护组合物，其特征在于，包括防晒修护组分，以防晒修护组合物总量计，所述防晒修护组分包括以下质量百分比的组分：防晒剂组合物0.05％-50％；所述防晒剂组合物由甲氧基肉桂酸异戊酯、硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪、二乙氨基羟苯甲酰基苯甲酸己酯、苯基苯并咪唑磺酸和亚甲基双-苯并三唑基四甲基丁基酚组成。
- 根据权利要求1所述防晒修护组合物，其特征在于，所述防晒剂组合物中，甲氧基肉桂酸异戊酯、硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪、二乙氨基羟苯甲酰基苯甲酸己酯、苯基苯并咪唑磺酸和亚甲基双-苯并三唑基四甲基丁基酚占防晒修护组合物总量的质量百分比分别为0.01％-10％，0.01％-10％，0.01％-10％，0.01％-10％，0.01％-10％。
- 根据权利要求1所述防晒修护组合物，其特征在于，所述防晒修护组分还包括防御因子组合物，所述防御因子组合物由以防晒修护组合物总量计的以下质量百分比组分组成：小果咖啡籽提取物0.0001％-5％，肌肽0.0001％-5％。
- 根据权利要求1-3任一项所述防晒修护组合物，其特征在于，所述防晒修护组分还包括增效剂，所述增效剂以防晒修护组合物总量计的质量百分比为0.0001％-5％。
- 根据权利要求4所述防晒修护组合物，其特征在于，所述增效剂为聚C10-30烷醇丙烯酸酯。
- 根据权利要求5所述防晒修护组合物，其特征在于，所述防晒修护组分还包括生物活性组合物，所述生物活性组合物由糖类同分异构体、富勒烯分散液、维C乙基醚、抗污染藻提取物和四氢甲基嘧啶羧酸组成。
- 根据权利要求6所述防晒修护组合物，其特征在于，所述生物活性组合物 中，糖类同分异构体、富勒烯分散液、维C乙基醚、抗污染藻提取物和四氢甲基嘧啶羧酸以防晒修护组合物总量计的质量百分比分别为0.0001％-5％，0.0001％-5％，0.0001％-5％，0.0001％-5％，0.0001％-5％。
- 一种权利要求7所述防晒修护组合物的制备方法，其特征在于，包括以下步骤：(1)向甲氧基肉桂酸异戊酯、二乙氨基羟苯甲酰基苯甲酸己酯与聚C10-30烷醇丙烯酸酯中加入油相溶剂加热溶解，得到油相防晒修护组合物；(2)用碱液将苯基苯并咪唑磺酸中和成盐，然后再加入亚甲基双-苯并三唑基四甲基丁基酚搅拌溶解，得到水相防晒修护组合物；(3)将步骤(1)油相与步骤(2)水相进行混合，加热均质乳化均匀，降温，再加入硅石包裹的双-乙基己氧苯酚甲氧苯基三嗪、加入四氢甲基嘧啶羧酸、小果咖啡籽提取物、肌肽、糖类同分异构体、抗污染藻提取物、富勒烯分散液、维C乙基醚搅拌分散均匀，得到防晒修护组合物。
- 根据权利要求8所述防晒修护组合物的制备方法，其特征在于，步骤(1)加热温度为80-90℃；步骤(3)中均质温度为75-85℃，降温为降至50℃以下。
- 根据权利要求8所述防晒修护组合物的制备方法，其特征在于，步骤(2)中碱液为精氨酸。
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