WO2023230071A1

WO2023230071A1 - Near infrared spectroscopy device control and operation

Info

Publication number: WO2023230071A1
Application number: PCT/US2023/023247
Authority: WO
Inventors: Roy STILLWELL; Thomas O'sullivan; Adam LONGORIA; Eric SHEEDER; Lyla SENN
Original assignee: Nearwave Corp.
Priority date: 2022-05-23
Filing date: 2023-05-23
Publication date: 2023-11-30

Abstract

Methods, systems, and apparatus, including computer programs encoded on computer storage media relate to a method for frequency a near infrared spectroscopy (NIRS) device control and operation. Scanning operations may be performed via a client device that controls and/or interacts with the NIRS device. The client device may display various user interfaces to select modes of operation of the NIRS device and display in-real time scanning data generated by the NIRS device. Described herein are methods, systems, and apparatus, including computer programs encoded on computer storage media related to a method for near infrared spectroscopy device (e.g., a frequency domain diffuse optical spectroscopy (FD-DOS) device, a frequency domain near infrared spectroscopy (fdNIRS) device, a time domain near infrared spectroscopy (tdNIRS) device, or a continuous wave near infrared spectroscopy (cwNIRS) device) control and operation.

Description

NEAR INFRARED SPECTROSCOPY DEVICE CONTROL AND OPERATION

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application is a continuation of, and claims priority to, United States provisional application number 63/345,025, titled Near Infrared Spectroscopy Device Control and operation, filed May 23, 2023, and is related to United States application number 17/045,070, titled Frequency Domain Diffuse Optical Spectroscopy Device and Optical Detector Calibration Method filed April 5, 2019, which are both hereby incorporated by reference in its entirety.

FIELD

[0002] This application relates generally to control and operation of a near infrared spectroscopy device (NIRS) device, and more particularly, to systems and methods for control and operation of a NIRS device.

BACKGROUND

[0003] U.S. patent application number 17/045,070 describes a frequency domain diffuse optical spectroscopy (FD-DOS) device and calibration method. The FD-DOS device includes a radio frequency signal generator, a driver, a light source, a silicon photomultiplier, an analog to digital conversion circuit, and an electronic processing circuit. The light source is configured to generate modulated light at a plurality of different wavelengths and modulation frequencies. The silicon photomultiplier is configured to generate analog detection signals indicative of detected optical signals. The analog to digital conversion circuit is configured to generate digital sample values from the analog detection signals. The electronic processing circuit is configured to determine absorption values and scattering values based on the digital sample values. The electronic processing circuit is also configured to determine concentration values based on the absorption values and the scattering values. The electronic processing circuit is further configured to determine an image stream based on the concentration values.

SUMMARY

[0004] Described herein are methods, systems, and apparatus, including computer programs encoded on computer storage media related to a method for near infrared spectroscopy device (e.g., a frequency domain diffuse optical spectroscopy (FD-DOS) device, a frequency domain near infrared spectroscopy (fdNIRS) device, a time domain near infrared spectroscopy (tdNIRS) device, or a continuous wave near infrared spectroscopy (cwNIRS) device) control and operation. The control and operation will be described as to a NIRS device, but is applicable to an FD-DOS device, to an fdNIRS device, to an tdNIRS device or to an cwNIRS device. A NIRS device scanning operations may be performed via a client device that controls and/or interacts with the NIRS device. The client device may display various user interfaces to select modes of operation of the NIRS device and display in real time scanning data generated by the NIRS device.

[0005] In some embodiments, a system and method provides for display a user interface that includes multiple scanning mode options. The scanning mode options are configurable via a user interface. In one mode of operation a user selects one of the scanning mode options to being a scan using a NIRS device. The NIRS device comprises a plurality of laser diodes have different wavelengths and a plurality of optical sensors to receive light reflected from the plurality of laser diodes.

[0006] In response to the selection, a client device send configuration parameters from the client device to the NIRS device and the NIRS device begins a scanning operation based on the configuration parameters. The system provides for display a user interface that has a data display portion to display a data from the NIRS device and a gradient scale. The NIRS device is instructed to perform a scanning operation based on the selected scanning mode option. A client device receive scanning data from the NIRS device while the NIRS device performs the scanning operation, and displays in the data in display portion of a user interface.

[0007] In some embodiments, a user interface including multiple scanning mode options is displayed via a client device. A user may select one of the scanning mode options. Each of the selectable scanning modes include parameters used to configure or initialize the NIRS device for scanning operation operations.

[0008] In some embodiments, in response to the selected scanning mode a user interface is displayed which allows a user to select a particular area of a patient’s anatomy to scan and the adjust a size of a scan area of the patient. For example, the scanning mode options may include an option for scanning muscle tissue and an option for scanning breast tissue. Also, the scanning mode options may be user configurable and/or include preconfigured scanning mode options. For example, the scanning mode options may be configurable to select a particular wavelength used for a scanning operation.

[0009] In some embodiments, for scanning operations, a user interface is displayed for presenting scanning data received from the NIRS device in a graphical format via a scan grid portion of the user interface. The user interface may include a gradient scale related to the displayed scanning data.

[0010] In some embodiments, the NIRS device includes six laser diodes having the wavelengths of about 690 nanometers (nm), about 785 nm, about 808 nm, about 850 nm, about 940 nm and about 980 nm. Various user interfaces may display scanning data received from the NIRS device. [0011] Further areas of applicability of the present disclosure will become apparent from the detailed description, the claims and the drawings. The detailed description and specific examples are intended for illustration only and are not intended to limit the scope of the disclosure.

BRIEF DESCRIPTION OF THE DRAWINGS

[0012] The present disclosure will become better understood from the detailed description and the drawings, wherein:

[0013] FIG. 1A is a diagram illustrating an exemplary environment in which some embodiments may operate.

[0014] FIG. IB is a diagram illustrating an exemplary processing engine that may execute some of the functionality described herein.

[0015] FIG. 2 is a flow chart illustrating an exemplary method that may be performed in some embodiments.

[0016] FIG. 3 is a diagram illustrating an exemplary environment in which some embodiments may operate.

[0017] FIG. 4 is a flow chart illustrating an exemplary method that may be performed in some embodiments.

[0018] FIG. 5 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0019] FIG. 6 illustrates an exemplary user interface according to one embodiment of the present disclosure. [0020] FIG. 7 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0021] FIG. 8 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0022] FIG. 9 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0023] FIG. 10 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0024] FIG. 11 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0025] FIG. 12 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0026] FIG. 13 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0027] FIG. 14 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0028] FIG. 15 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0029] FIG. 16 illustrates an exemplary user interface according to one embodiment of the present disclosure. [0030] FIGS. 17A-17B illustrate an exemplary user interface according to one embodiment of the present disclosure.

[0031] FIG. 18 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0032] FIG. 19 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0033] FIG. 20 illustrates an exemplary scanning operation and a depiction of amplitude and phase data received from the NIRS device.

[0034] FIGS. 21A-21B illustrate an exemplary user interface 1800 according to one embodiment of the present disclosure.

[0035] FIG. 22 illustrates exemplary graphs depicting absorption coefficient and associated wavelengths.

[0036] FIG. 23 illustrates an exemplary user interface according to one embodiment of the present disclosure.

[0037] FIG. 24 is a diagram illustrating an exemplary computer that may perform processing in some embodiments.

DETAILED DESCRIPTION OF THE DRAWINGS

[0038] In this specification, reference is made in detail to specific embodiments of the invention. Some of the embodiments or their aspects are illustrated in the drawings.

[0039] For clarity in explanation, the invention has been described with reference to specific embodiments, however it should be understood that the invention is not limited to the described embodiments. On the contrary, the invention covers alternatives, modifications, and equivalents as may be included within its scope as defined by any patent claims. The following embodiments of the invention are set forth without any loss of generality to, and without imposing limitations on, the claimed invention. In the following description, specific details are set forth in order to provide a thorough understanding of the present invention. The present invention may be practiced without some or all of these specific details. In addition, well known features may not have been described in detail to avoid unnecessarily obscuring the invention.

[0040] In addition, it should be understood that steps of the exemplary methods set forth in this exemplary patent can be performed in different orders than the order presented in this specification. Furthermore, some steps of the exemplary methods may be performed in parallel rather than being performed sequentially. Also, the steps of the exemplary methods may be performed in a network environment in which some steps are performed by different computers in the networked environment.

[0041] Some embodiments are implemented by a computer system. A computer system may include a processor, a memory, and a non-transitory computer-readable medium. The memory and non-transitory medium may store instructions for performing methods and steps described herein.

[0042] FIG. 1A is a diagram illustrating an exemplary environment in which some embodiments may operate. In the exemplary environment 100, a client device 150 includes a processing engine 102. The processing engine 102 is communicatively coupled to one or more NIRS devices 120.

[0043] In an embodiment, processing engine 102 may perform the methods 200, 400 or other methods described herein. In some embodiments, this may be accomplished via communication with the client device 150 and the NIRS device 120 over a communications network 110 (e.g., Wi-Fi, BlueTooth wireless connection, and/or a hard-wired connection) between the device(s). In some embodiments, the processing engine 102 is an application, browser extension, or other piece of software hosted on the client device 150.

[0044] In some embodiments, the client device 150 and additional users’ client devices 151 may perform the methods 300, 400 or other methods herein and, as a result, provide configuration and scanning operations using the NIRS device 120.

[0045] The client device 150 may be a device with a display configured to present information to a user of the device. In some embodiments, the client device 150 present information in the form of a user interface (UI) with UI elements or components. In some embodiments, client device 150 sends and receives signals and/or information via the processing engine 102 to the NIRS device 120. The client device 150 may be configured to perform functions related to interaction, configuration and/or control of the NIRS device 120. In some embodiments, the client device 150 initiates a scanning operation and receives sensor data obtained by the NIRS device 120.

[0046] In some embodiments, optional repositories can include one or more of: a scanning mode profile repository 130, patient information repository 134 and a scanning data repository 136. The scanning mode profile repository may store information related to parameters and configurations used for different scanning mode for a NIRS device 120. The patient information repository 134 may store information related to a patient, such as a patient identifier and scanning operation notes. The scanning data repository 136 may store information related to received scanning data transmitted from the NIRS device 120 to the client device 150. [0047] FIG. IB is a diagram illustrating an exemplary processing engine 102 that may execute some of the functionality described herein. The User Interface Module 152 provides system functionality for presenting one or more user interfaces via the client device 150. User inputs received by the user interface herein may include clicks, keyboard inputs, touch inputs, taps, swipes, gestures, voice commands, activation of interface controls, and other user inputs. In some embodiments, the User Interface Module 152 presents a visual user interface on a screen. In some embodiments, the user interface may comprise audio user interfaces such as sound-based interfaces and voice commands.

[0048] The Scanning Mode Configuration Module 154 provides system functionality for the selection of, creation of and/or configuration of scanning modes to be used in conjunction with the NIRS device 120. The scanning modes may be configured to use different laser diode sources of the NIRS device 120. A user may create a customized scanning mode that may be selectable via a user interface to perform scanning operations based on the parameters configured for the scanning mode.

[0049] The Scanning Operation Module 158 provides system functionality for the control and operation of the NIRS device 120. The Scanning Operation Module 158 provides instructions to the NIRS device to begin a scanning operation and receives scanning data from the NIRS device. The received scanning data may be stored in Scanning Data Repository 136 and associated with a patient identifier. The Scanning Operation Module 158 may send initialization parameters to the NIRS device 120 based on a particular scanning mode selected by a user.

[0050] The Calibration Module 160 provides system functionality for the calibration of the

NIRS device 120. In one mode, the system may perform a calibration operation (as described herein) to calibrate the different laser diode sources against a test phantom. [0051] FIG. 2 is a flow chart illustrating an exemplary method 200 that may be performed in some embodiments. The NIRS device 120 may be calibrated from time-to-time to ensure the scanning data is accurate. Calibration may be ideally performed prior to performing a scanning procedure on a patient. In step 210, the NIRS device 120 is placed into a calibration mode of operation. In step 120, the NIRS device may scan a test phantom. The test phantom is made of a material of a known absorption level for the various wavelengths of the different laser diode sources. In step 230, the NIRS 120 device obtains scanning data using the different laser diode sources. Each of the laser diode sources may be operated individually and/or simultaneously while performing the scanning of the test phantom. In one embodiment, the NIRS 120 device transmits to and the client device 150 receives the scanning data. In another embodiment, the NIRS 120 device does not send the scanning data to the client device, but instead performs the calibration procedure in a self-calibrating mode. In step 240, the obtained scanning data is compared to known calibration standard data. The scanned data for each of the laser diodes may be compared against the known calibration data. Deviations in the scanned data and the calibration standard data may be determined. In step, 250 the NIRS 120 device may be calibrated based on the deviation of the scanning data as compared to the known calibration data. In step 260, the calibration procedure may be re-run until the NIRS device 120 is calibrated. An adjustment table (e.g., calibration table) may be created by the calibration procedure to adjust data values generated by the laser diode sources. The adjustment table may be used then to modify scanning data values obtained by the NIRS device 120.

[0052] FIG. 3 is a diagram illustrating an exemplary environment in which some embodiments may operate. As discussed previously, the NIRS device 120 may be calibrated to adjust scanning data values of the laser diode sources. A cradle 300 including a charger 302 and a phantom test portion 304 may be used with the NIRS device 120. In one embodiment, the phantom test portion may be a silicone-based test phantom 304. Auser may insert the NIRS device 120 into the cradle. The cradle 300 may include a calibration activation switch or button 310. Activating the switch causes the NIRS device 120 to perform a self-calibration process (e.g., as described herein) using the silicone-based test phantom 304. In one embodiment, the test phantom 340 is comprised of at least four components: water-soluble nigrosin ink to control absorption properties, anatase titanium (IV) oxide scattering properties p4 silicone rubber base and activator.

[0053] FIG. 4 is a flow chart illustrating an exemplary method 400 that may be performed in some embodiments. The system 100 may perform a method of performing a scanning operation based on a selected scanning mode. In step 410, the client device 150, via a user interface, may receive a selection for a scanning mode among an option of different scanning modes. Each of the scanning modes include associated parameters to configure the NIRS device 120 to operate in a particular manner to perform a scanning operation. In step 420, based on the selected scanning mode, the client device 150 provides instructions to the NIRS device 120 which configures the NIRS device to a particular mode of operation. In step 430, the client device 150 may display a user interface to displaying in a graphical form. The user interface may include a scan grid portion in which the scanning data is presented in a color scale. In step 440, the client device 150 sends instructions to the NIRS device to begin a scanning operation. In other embodiments, the NIRS device 120 may be activated with a button or other control on the NIRS device 120 and beings the scanning operation. In step 450, while the NIRS device 120 scans an area of a patient’s anatomy, the NIRS device 120 transmits scanning data to the client device 150. In step 460, the scanning operation is completed when the NIRS device scan operation is terminated either from the NIRS device 120 or from the client device 150. To assist in the scanning operation, a fiducial marker may be placed on a patient’s body. The fiducial marker may be used to provide a reference point for the NIRS device for the scanning operation.

[0054] During the scanning operations, the NIRS 120 may utilize individually and in any combination six laser diodes which are configured to emit a distinct wavelength of light. For example, in some embodiments the six laser diodes have wavelengths of about 690 nanometers (nm), 785 nm, 808 nm, 850 nm, 940 nm and 980 nm. Sensors on the device receive and interpret wavelengths of light reflected from body tissue, cells, fluid, masses, and other structures of the body. The wavelengths of the laser diodes of the NIRS device 120 may be in a range of +/- 10 nanometers of the noted nanometers values.

[0055] Depending on the selected scanning mode, chromophores (i.e., biomarkers) may be displayed such as (1) Deoxy-hemoglobin: HHb or ctHHb (pM); (2) Oxy-hemoglobin : HbO2 or ctHbO2 (pM); (3) Total blood volume: THb:(THb = ctHHb + ctHbO2); (4) Lipid concentration: % and/or (5) Water concentration: %. The NIRS device 120 may evaluate amplitude (dBFS) which is the electrical signal obtained from an optical signal detector detected.

[0056] In some embodiments, while the scanning operation is performed the scanning data may be sent to another remote device (such as another client device, server or a web application). The remote device may be configured with a similar user interface of those described herein, thereby allowing the remote viewing of a real time scanning operation. For example, the Remote Monitoring Module 162 provides functionality to manage remote communications to other devices and transmits real time information of the scanning data while a scanning operation is performed. Similar screen data of the figures depicting the scanning data may also be displayed to the remote users. [0057] FIG. 5 illustrates an exemplary user interface 500 according to one embodiment of the present disclosure. The client device 150 may present a user interface presenting different NIRS devices that may be used in conjunction with the client device 150. The user interface 500 may receive an input to select a NIRS device 120 to be used for subsequent scanning operations. For example, multiple NIRS device may be associated with a particular client device 150.

[0058] FIG. 6 illustrates an exemplary user interface 600 according to one embodiment of the present disclosure. The user interface 600 provides a Scan Settings selection portion 602 allowing a user to select a scan settings type for a ID Plot scan, 2D Image scan, or 3D interpretation of the data. A scanning subject may be selected as a lab subject or a patient subject. The lab subject option would be selected to scan a control subject. The patient subject option would be selected to scan a patient. In this example, the user has selected the option to perform a ID Plot Scan for a laboratory control subject.

[0059] FIG. 7 illustrates an exemplary user interface 700 according to one embodiment of the present disclosure. The user interface 700 depicts an example interface of a ID Plot scan (e.g., as selected with regard to FIG. 6) illustrating a scanning operation where the NIRS device uses six different wave lengths of 690 nanometers (nm), 785 nm, 808 nm, 850 nm, 940 nm and 980 nm. The user interface allows for the toggling on/off of the sensor data for particular wave lengths being displayed in the respective plot graph sections 702, 704, 706, 708, 710, 712. Plot graph section 702 displays an amplitude graph of the wavelengths. Plot graph section 704 displays an absorption graph. Plot graph section 706 displays an HbO2 graph. Plot graph section 708 displays a phase (degree) graph. Plot graph section 710 displays a Scattering graph. Plot graph section 712 displays an Hhb graph. [0060] FIG. 8 illustrates an exemplary user interface 800 according to one embodiment of the present disclosure. In this example, the user has selected the option to perform a 2D Plot Scan for a laboratory control subject. The user interface provides user interface controls to adjust a dimension size for an area to be scanned. In this example, a height and length of a scan area may be adjusted using a slider bar controls 810, 820.

[0061] FIG. 9 illustrates an exemplary user interface 900 according to one embodiment of the present disclosure. The user interface 900 depicts an example interface of a 2D Plot scan (e.g., as selected with regard to FIG. 8) illustrating a scanning operation where the NIRS device uses six different wave lengths of 690 nm, 785 nm, 808 nm, 850 nm, 940 nm and 980 nm. The user interface allows for the toggling 920 on/off of sensor data for particular wave lengths being displayed in the scan grid portion 902 of the user interface 900. Scanning data transmitted by the NIRS device 120 and received by the client device 150 is depicted in a color scale and represents the scanning data of the various wave lengths. The system may determine based on the received scanning data various information. For example, the system may display a user interface 900 having a gradient indication 910 of a Total Optical Index (TOI). The TOI may indicate a combination one or more of a lipid concentration percentage, water concentration percentage, Deoxy-hemoglobin: HHb or ctHHb (pM), Oxy-hemoglobin: HbO2 or ctHbO2 (pM). The system may determine and display information regarding: Arterial oxygen saturation: SpO2 (%), Tissue oxygen saturation (tissue perfusion): StCh (%).

[0062] FIG. 10 illustrates an exemplary user interface 1000 according to one embodiment of the present disclosure. The user interface 1000 depicts an example interface of the selection of a 2D Plot Scan for a patient. In this example, in response to the selection of the 2D Plot and Patient settings, the user interface 1000 displays multiple tissue scan types (such a scan type for breast tissue or muscle tissue). The tissue scan type may have predetermined settings that are associated with the tissue scan type. The selection of a tissue scan type would then initialize the NIRS device 120 to operate the laser diodes power according to the predetermined settings.

[0063] FIG. 11 illustrates an exemplary user interface 1100 according to one embodiment of the present disclosure. In this example, the user has selected to perform a breast tissue scan with regard to FIG. 10. In response to the selection of the breast tissue scan, the example user interface 1100 is displayed by the client device 150. The user interface 1100 provides an option to select a left or right breast for scanning operations.

[0064] FIG. 12 illustrates an exemplary user interface according to one embodiment of the present disclosure. In this example, scanning data is presented via the display section 1202. The various laser diodes may be toggled on/off to display associated data for the respective laser diode sources. The user interface 1200 provides a user interface portion that displays the various laser diode sources (e.g., 690 nm, 808 nm, 940 nm, 785 nm, 850 nm, 980 nm).

[0065] FIG. 13 illustrates an exemplary user interface 1300 according to one embodiment of the present disclosure. The user interface 1000 may display a title section providing a description of the user interface 1000 (e.g., Mode Selection). The title section depicts an icon showing the number of sensors to be used (e.g., Z6), a frequency range may be displayed (e,g., f: 400), the battery charge of the NIRS device, and whether the connection of the system 100 to the NIRS device 120. The user interface 1000 provides for the selection of different types of scanning modes that may be performed by the NIRS device 120. For example, a user may select one of the scanning modes, such as a muscle scan or a breast scan. In response to the selection of the scan, the system will communicate to the NIRS device 120 to initialize the NIRS device 120 to perform the selected scanning mode. [0066] The user interface 1300 allows for the selection of one of the scanning modes 1302, 1304, 1306. Once the mode is selected the scanning operation may continue to the next scanning operation user interface by receiving an input on the select button 1308. The user interface 1300 allows a user to create a new scanning mode by selecting the create new button 1310. The create new button displays a user interface for creating of the new scanning mode (e.g., the user interface of FIGS. 21 A-21B.) Parameters for a new scanning mode may be set, such as a description of the scanning mode, and icon representing the scanning mode, one or more wave lengths (i.e., laser diode sources to be used for the scanning mode, a preset area or initial grid size for the associated scanning operation, a duration for the associated scanning operation, the number of measurements to be taken, and other information. Other settings may include: whether the scan is for a ID plot or a 2D scan, the type of measurements made: such as Deoxy-hemoglobin: HHb or ctHHb (pM), Oxy-hemoglobin : HbO2 or ctHbO2 (pM), Total blood volume: THb : (THb = ctHHb + ctHbO2), Lipid concentration: %, Water concentration: %, Arterial oxygen saturation: SpO2 (%), tissue oxygen saturation (tissue perfusion): StO2 (%) and/or a combination of any of the foregoing. Other settings may include the particular wave lengths to be used, the frequency range of the wave lengths and/or a step size for modulating among frequencies.

[0067] The created scanning mode may be saved and would be depicted in the list of available scanning modes. Information about the created scanning mode may display any combination of the following information: the scanning mode description, the mode type (as ID or 2D), the number of laser diode sources used for the scanning operation, the frequency range, the duration of the scanning operation, the number of measurements to be taken, the grid size for the scanning operation, and an associated image for the scanning mode. [0068] In one embodiment, the client device 150 connects to the NIRS device 120 via a secured encrypted connection. The parameter settings for the selected mode are transmitted via a configuration file (such as a JSON txt file). The NIRS device 120 then reads the configuration file and sets the device to perform a scanning operation according to the parameter settings.

[0069] FIG. 14 illustrates an exemplary user interface 1400 according to one embodiment of the present disclosure. The user interface 1400 may display a title section providing a description of the user interface 1400, which is 2D Patient: Scan Set-up. The system 100 may present a scanning template in response to the select scanning mode of FIG. 13. In this example, a scanning template for a breast scan is depicted.

[0070] The user interface 1400 allows for the selection of a right or left breast to scan. A width and height of a grid may be adjusted by increasing or decreasing the grid. Optionally, an image may be captured depicted an area of a patient’s body where the scan is to be performed.

[0071] FIG. 15 illustrates an exemplary user interface 1500 according to one embodiment of the present disclosure. The user interface 1500 may display a title section 1504 providing a description of the user interface 1500, which is 2D Patient: Scanning. The system 100 may present real time scanning of patient information. The user interface 1500 may present a grid may be depicted that corresponds to the size of as modified in in the user interface 1400 of FIG. 14. The user interface 1500 may display a test type 1506, a test type gradient 1508, a description of the selected body anatomy being scanned 1510 (e.g., a selected right breast), a scan area size 1512, and a scan grid portion 1518. The scan grid portion 1518 may be increased by the selecting the grid increase icon 1522. In one embodiment, the size of the grid portion will be increased by a predetermined size (e.g., 1 centimeter). The system 100 receives scanning data from the NIRS device 120 while the NIRS device 120 performs a scanning operation. The user interface 1500 displays in the scan grid portion 1518 a graphical representation of the received scanning data according to the test type gradient scale. The user interface 1500 may display a scanning guide path 1520 to provide a visual guide to assist operator of the NIRS device 120 in the movement of the NIRS device along a patient’s scanned anatomy.

[0072] FIG. 16 illustrates an exemplary user interface 1600 according to one embodiment of the present disclosure. The user interface 1600 depicts a completed scanning operation of the scan of FIG 15. The user interface 1600 graphically depicts the completed scan depicts in a color scale according to the test type gradient. In this example, a test type gradient for deoxygenated hemoglobin (i.e., dexoxyhemoglobin) is depicted. For example, scanning data from the NIRS device 120 received by the client device 150 may include amplitude and/or phase of reflected light for the various wave lengths of the laser diode sources. The amplitude and phase information may be used to calculate optical properties which indicate absorption in the tissue are being scanned.

[0073] FIGS. 17A-B illustrate an exemplary user interface 1700 according to one embodiment of the present disclosure. The example user interface 1700 illustrates a scanning operation in a 2D scan where the NIRS device 120 is being scanned in a swirling circular like pattern. Data obtained by the NIRS device 120 is displayed in real time during the scan. FIG. 17A depicts an earlier stage of the scan and FIG. 17B depicts a later stage of the scan.

[0074] Intermediate points of data between two or more other points of data are interpolated while the scan is being performed. While more data obtained are obtained by the NIRS device 120, the depicted data in the user interface 1700 become more accurate and in some areas no interpolation of data is needed. [0075] The user interface 1700 may toggle a display selection between depicting amplitude or phase data received from the NIRS device. A user may toggle the Amp and Phase controls to display either type of data.

[0076] The user interface 1700 may display different data in various wave lengths. In some embodiments, the user interface is configured to display wave lengths of 690 nm, 785 nm, 808 nm, 850 nm, 940 nm and 980 nm. The user interface 1700 may be configured to display data for other wave lengths.

[0077] The user interface 1700 may toggle between auto scaling and a set range of data. A user may toggle the Autoscale slider control to turn on/off data autoscaling functionality. Otherwise, a user may select a top range and a lower range of a scale. Based on the selected top range and lower range of data meeting that criteria would be displayed in a data display portion of the user interface. The user interface 1700 may display a legend with a color gradient being associated with a color of data displayed in the data display portion of the user interface 1700.

[0078] FIG. 18 illustrates an exemplary user interface 1800 according to one embodiment of the present disclosure. The example user interface 1800 is configured to display scanned data in a data display portion during a 2D scan. Data obtained by the NIRS device 120 may be displayed in the data display portion in real time during the scan.

[0079] In some embodiments, the user interface 1800 includes a Grid option to change a type of grid over the display portion. The grid may be turned off, may be shown with dots, shown with origins or shown with lines.

[0080] In some embodiments, the resolution of the user interface may be change to increase or decrease the resolution size of the data displayed. For example, the display portion may display data increments of pixels/millimeter. The number of pixels per millimeter displayed may be increased or descreased using the +/- buttons.

[0081] The user interface 1800 may toggle a display selection between depicting amplitude or phase data received from the NIRS device. A user may toggle the Amp and Phase controls to display either type of data.

[0082] The user interface 1800 may display different data in various wave lengths. In some embodiments, the user interface is configured to display wave lengths of 690 nm, 785 nm, 808 nm, 850 nm, 940 nm and 980 nm. The user interface 1700 may be configured to display data for other wave lengths.

[0083] The user interface 1800 also provides functionality to show a current cursor position and/or show plotted points of data via the data display portion of the user interface.

[0084] The user interface 1800 may toggle between auto scaling and a set range of data. A user may toggle the Autoscale slider control to turn on/off data autoscaling functionality. The user interface 1800 may display a legend with a color gradient being associated with a color of data displayed in the data display portion of the user interface 1800.

[0085] FIG. 19 illustrates an exemplary user interface 1900 according to one embodiment of the present disclosure. The user interface 1900 provides functionality to show real time data over a period of time. One portion of the user interface 1900 includes amplitude display portion and another portion of the user interface 1900 includes a phase display portion. In some embodiments, both the amplitude display portion and the phase display portion allows for the selection and display of different types of data. The data displayed is similar to the graph data as depicted in FIG. 7. FIG. 19 provides a drop-down selector that allows for the selection of one or more types of data including Amplitude (time), Amplitude Frequency, Absorption, Phase (time), Phase (frequency), Scattering, HHb, HbO2, H20 and Lipid data.

[0086] FIG. 20 illustrates an exemplary scanning operation and a depiction of amplitude, phase or optical property data received from the NIRS device. During scanning operations, an operator of the NIRS device 120 may scan a location of a person’s anatomy. Graph 2002 depicts an example of an operator performing a scanning operating by using a circular or swilling pattern about an area of the person. The client device may receive data from the NIRS device 120 and determine a two-dimensional (2D) plot in real time. 2002 depicts underlying tissue properties over a 2D grid. Graphs 170 and 1706 depict two asymmetric gaussians depicting a detected tumor. These 2D may be depicted via a user interface of the client device while the operating is performing the scanning operation.

[0087] The NIRS device 120 may generate data and transmit the data to the client device 150 which receives the data and may process the data for presentation via the user interfaces as described herein. In some embodiments, sparse data is captured by the NIRS device 120. The sparse data, for example, may be data tied to the x/y positions that sensors of the NIRS device 230 recorded while data was being sampled from a person’s anatomy. A NIRS device 120 and/or the client device 150 may interpolate the tissue properties in the spaces in-between each data point, as related to each other data point. Interpolated image may be updated in real time. Based on the interpolation and display via the user interfaces as described herein.

[0088] The user interfaces, as described herein, may display data in color gradients. For example, color schemes for displaying the data may be selected by the user. The color schemes may be changed to any arbitrary color range or may be changed to selected color range presets. The colors are scaled based on the measured sample values. Users may adjust the contrast, intensity, brightness, and other settings to enhance the image.

[0089] FIGS. 21A-21B illustrate an exemplary user interface 2100 according to one embodiment of the present disclosure. The user interface 2100 provides functionality to customize a scanning mode. The customized scanning mode may be presented in a user interface as depicted in FIG. 13. The attributes selected in this customization interface 2100 would be used for the customized scanning mode.

[0090] The modality 2101 of the scanning mode may be set to ID or 2D. This selection set the operation and user interface to perform a ID or 2D scanning. Also, the customized scanning mode may be set to a lab mode or a patient mode.

[0091] A scan icon 2102 may be associated with the scanning mode. A user may select an icon to associate with the scanning mode. In some embodiments, the user interface may use a customized icon selected from a storage device or file system.

[0092] A measurement name and folder name 2103 may be set for the scanning data. The measurement name is used to reference a measurement data file and may have multiple increments for multiple measurements. The folder name is the folder where the measure data would be stored.

[0093] A data type 2104 of may be set. For example, the data type may be set to ampPhase, ops or chromophores. The ampPhase setting provides a mode that displays raw data such as amplitude and phase data. The Ops setting provides a mode that displays optical properties such as absorption and scattering. The chromophores setting provides a mode that displays chromophores, such as micromolar of the oxymoglobin, micromolar of hemoglobin, lipid water percentages, met hemoglobin, etc. [0094] A tracking LED of the NIRS device 120 may be set to be turned on or off. The NIRS device 120 includes a tracking LED, for example an 850 nanometer LED may be used for tracking of the NIRS device 120 while performing scanning operations of a patient. A number of measurements 2106 and intervals in seconds may be set. For example, The NIRS device 120 may be set to obtain a number of data measurements per second. A scanning range or frequency range 2108 may be set. A step size may be set. The scanning configuration parameters may be saved. A sample size 2109, and attenuator value and a DDS Current value may be set. Also, a selected mode name may be set for the particular customized scanning mode.

[0095] A Nyquist Tolerance, and a type of Phantom Cal File and Phantom Dat File 2110 may be set. These files are used to calibrate the NIRS device 120 and may be created and/or stored using the calibration process as described with regard to FIG. 2.

[0096] A RHO in millimeters 2112 may be set to 20mm, 30 mm and or 40mm. The settings refer to optical sensors positioned on the scanning side of the NIRS device 120. These optical sensors may be configured to be turned on or turned off for the customized scanning mode. The NIRS device 120 may be configured for fewer or additional optical sensors. The optical sensors receive the reflected laser light from the laser sources of the NIRS device 120. This selecting allows a user to select which of two or more optical sensors receive light reflected from the plurality of laser diodes

[0097] A setting for each of the laser source of the NIRS device 120 may be turned on or turned off for the customized scanning mode. For example, the NIRS device 120 may have six laser diodes configured for different wave lengths, such as 689 nm, 785 nm, 808 nm, 850 nm, 940 nm and 980 nm. One or more of the laser source may be configured to used for the customized scan mode. [0098] In a scanning operation for the particular scanning mode, the saved parameter settings would be used to configure the NIRS device 120 to perform the scanning operation. The client device 150 sends some of the saved parameter settings to the NIRS device 120, such as the parameters for the laser sources, RHO in MM, measurements, frequency, sample size, attenuator and DDS current values. The NIRS device 120 receives these parameters and configures the NIRS device 12 based on these settings.

[0099] In a scanning operation for the particular scanning mode, the saved parameter settings would be used to perform client device 150 display and file operations. For example, scanning data would be stored according to the measurement name and folder name parameters. A user interface would be selected based on the modality of the scan such as ID or ID.

[0100] In some embodiments, interpolation of data may be set based on a user preference or a default parameter, such as a linear, cubic, bi-cubic, among others. The user interface may receive a selection from input by a user to toggle measured points for display on a plot or alternatively display just the interpolated image. In some embodiments, the user interface 2100 may select an averaging method to be used on the measured samples, that are processed on the client device 150. For example, some averaging methods that may be selected are the following: x/y spatial averaging, block averaging, exponential average, moving window average, among others.

[0101] In some embodiments, data may be captured from the NIRS device 120 utilizing a custom streaming interface based on a custom TCP/IP packet protocol to enhance speed and reliability. The data packets may comprise the following information: amplitude/phase values, optical absorption and scattering values, biomarker values, x/y spatial location values, and 3D orientation values of the NIRS device 120. The client device 150 may buffer the sample data into memory as raw packets, via a thread, are received by the client device 150. The client device 150 may process and interpolate the received data, verify sample integrity of the received data, discard poor data, and calculate 2-dimensional and 3- dimensional spatial interpolation for display.

[0102] In some embodiments, the client device 150 may evaluate and/or control the quality of the received data. For example, a noise floor may be established upon measurement of a ‘dark’ (no signal) calibration. Signal to noise ratios (SNR) calculated based on this noise floor are used to filter good data samples from bad (low quality) data samples of data.

[0103] FIG. 22 illustrates exemplary graphs depicting absorption coefficient and associated wavelengths. The NIRS device 120 measures molecular absorption. Graphs 2202 and 2204 depicts the wavelengths on the x-axis and absorption coefficient on the y-axis. Graph 2202 depicts the measurement of HbO, Hb, Water and Lipids. Graph 2204 depicts the wavelengths of the NRIS device that are measures. In the example, the wavelengths that are measured are 680, 785, 808, 850, 940 and 980 nanometers.

[0104] FIG. 23 illustrates an exemplary user interface 2300 according to one embodiment of the present disclosure. The user interface 2300 depicts results of a completed scanning operation. In this example, the user interface displays a 2D line graph depicting concentrations of oxy- and deoxy-haemoglobin (HbCF and HhB) concentration levels over a time period.

[0105] FIG. 24 is a diagram illustrating an exemplary computer (e.g., the client device 150) that may perform processing in some embodiments. Exemplary computer 2400 may perform operations consistent with some embodiments. The architecture of computer 2400 is exemplary. Computers can be implemented in a variety of other ways. A wide variety of computers can be used in accordance with the embodiments herein. [0106] Processor 2401 may perform computing functions such as running computer programs. The volatile memory 2402 may provide temporary storage of data for the processor 2401. RAM is one kind of volatile memory. Volatile memory typically requires power to maintain its stored information. Storage 2403 provides computer storage for data, instructions, and/or arbitrary information. Non-volatile memory, which can preserve data even when not powered and including disks and flash memory, is an example of storage. Storage 2403 may be organized as a file system, database, or in other ways. Data, instructions, and information may be loaded from storage 2403 into volatile memory 2402 for processing by the processor 2401.

[0107] The computer 2400 may include peripherals 2405. Peripherals 2405 may include input peripherals such as a keyboard, mouse, trackball, video camera, microphone, and other input devices. Peripherals 2405 may also include output devices such as a display. Peripherals 2405 may include removable media devices such as CD-R and DVD-R recorders/players. Communications device 2406 may connect the computer 2400 to an external medium. For example, communications device 2406 may take the form of a network adapter that provides communications to a network. A computer 2400 may also include a variety of other devices 2404. The various components of the computer 2400 may be connected by a connection medium such as a bus, crossbar, or network.

[0108] It will be appreciated that the present disclosure may include any one and up to all of the following examples.

[0109] Example 1. A computer-implemented method comprising: providing for display a user interface comprising a plurality of scanning mode options; receiving a selection for one of the scanning mode options; providing for display a user interface comprising a scan grid portion and a gradient scale; instructing a Near Infrared Spectroscopy (NIRS) device to perform a scanning operation based on the selected scanning mode option, wherein the NIRS device comprises a plurality of laser diodes have different wavelengths; receiving in real time, scanning data from the NIRS device while the NIRS device performs the scanning operation; and displaying in the scan grid portion a graphical representation of the received scanning data according to the test type gradient scale.

[0110] Example 2. The computer-implemented method of Example 1, wherein the scanning graphical representation displays a two-dimensional representation of the scanning data in the scan grid portion of the user interface corresponding to the gradient scale.

[0111] Example 3. The computer-implemented method of any one of Examples 1-2, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue.

[0112] Example 4. The computer-implemented method of any one of Examples 1-3, wherein the plurality of laser diodes comprises six laser diodes have the wavelengths of about 690 nanometers (nm), about 785 nm, about 808 nm, about 850 nm, about 940 nm and about 980 nm.

[0113] Example 5. The computer-implemented method of any one of Examples 1-4, further comprising: providing for display a plot graph user interface comprising a plurality of plot graphs depicting aspects of the received scanning data, wherein the plot graph user interface includes graphical controls to hide or show the wavelengths being displayed in the plurality of the plot graphs.

[0114] Example 6. The computer-implemented method of any one of Examples 1-5, the computer-implemented method of claim 1, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue. [0115] Example 7. The computer-implemented method of any one of Examples 1-6, wherein one or more of the scanning mode options are configurable to select one or more of the plurality of laser diodes used for the scanning operation.

[0116] Example 8. The computer-implemented method of any one of Example 1-7, further comprising: providing for display a user interface comprising a line graph depicting HbCh and HhB concentration levels over a time period.

[0117] Example 9. The computer-implemented method of any one of Examples 1-8, wherein one or more of the scanning mode options are configurable to select the wavelengths used for the scanning operation.

[0118] Example 10. The computer-implemented method of any one of Examples 1-9, wherein one or more of the scanning mode options are configurable to select which of two or more optical sensors receive light reflected from the plurality of laser diodes.

[0119] Example 11. A non-transitory computer readable medium that stores executable program instructions that when executed by one or more computing devices configure the one or more computing devices to perform operations comprising: providing for display a user interface comprising a plurality of scanning mode options; receiving a selection for one of the scanning mode options; providing for display a user interface comprising a scan grid portion and a gradient scale; instructing a near infrared spectroscopy (NIRS) device to perform a scanning operation based on the selected scanning mode option, wherein the NIRS device comprises a plurality of laser diodes have different wavelengths; receiving in real time, scanning data from the NIRS device while the NIRS device performs the scanning operation; and displaying in the scan grid portion a graphical representation of the received scanning data according to the test type gradient scale. [0120] Example 12. The non-transitory computer readable medium of Example 11, wherein the scanning graphical representation displays a two-dimensional representation of the scanning data in the scan grid portion of the user interface corresponding to the gradient scale.

[0121] Example 13. The non-transitory computer readable medium of Examples 10-12, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue.

[0122] Example 14. The non-transitory computer readable medium of Examples 10-13, wherein the plurality of laser diodes comprises six laser diodes have the wavelengths of about 690 nanometers (nm), about 785 nm, about 808 nm, about 850 nm, about 940 nm and about 980 nm.

[0123] Example 15. The non-transitory computer readable medium of Examples 10-14, further comprising: providing for display a plot graph user interface comprising a plurality of plot graphs depicting aspects of the received scanning data, wherein the plot graph user interface includes graphical controls to hide or show the wavelengths being displayed in the plurality of the plot graphs.

[0124] Example 16. The non-transitory computer readable medium of Examples 10-15, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue.

[0125] Example 17. The non-transitory computer readable medium of Examples 10-16, wherein one or more of the scanning mode options are configurable to select one or more of the plurality of laser diodes used for the scanning operation. [0126] Example 18. The non-transitory computer readable medium of Examples 10-17, further comprising: providing for display a user interface comprising a line graph depicting HbCh and HhB concentration levels over a time period.

[0127] Example 19. The non-transitory computer readable medium of Examples 10-18, wherein one or more of the scanning mode options are configurable to select the wavelengths used for the scanning operation

[0128] Example 20. The non-transitory computer readable medium of Examples 101-9, wherein one or more of the scanning mode options are configurable to select which of two or more optical sensors receive light reflected from the plurality of laser diodes.

[0129] Example 21. A system comprising one or more processors configured to perform the operations of: providing for display a user interface comprising a plurality of scanning mode options; receiving a selection for one of the scanning mode options; providing for display a user interface comprising a scan grid portion and a gradient scale; instructing a near infrared spectroscopy (NIRS) device to perform a scanning operation based on the selected scanning mode option, wherein the NIRS device comprises a plurality of laser diodes have different wavelengths; receiving in real time, scanning data from the NIRS device while the NIRS device performs the scanning operation; and displaying in the scan grid portion a graphical representation of the received scanning data according to the test type gradient scale.

[0130] Example 22. The system of Example 21, wherein the scanning graphical representation displays a two-dimensional representation of the scanning data in the scan grid portion of the user interface corresponding to the gradient scale. [0131] Example 23. The system of Examples 21-22, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue.

[0132] Example 24. The system of Examples 21-23, wherein the plurality of laser diodes comprises six laser diodes have the wavelengths of about 690 nanometers (nm), about 785 nm, about 808 nm, about 850 nm, about 940 nm and about 980 nm.

[0133] Example 25. The system of Examples 21-24, further comprising: providing for display a plot graph user interface comprising a plurality of plot graphs depicting aspects of the received scanning data, wherein the plot graph user interface includes graphical controls to hide or show the wavelengths being displayed in the plurality of the plot graphs.

[0134] Example 26. The system of Examples 21-25, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue.

[0135] Example 27. The system of Examples 21-26, wherein one or more of the scanning mode options are configurable to select one or more of the plurality of laser diodes used for the scanning operation.

[0136] Example 28. The system of Examples 21-27, further comprising: providing for display a user interface comprising a line graph depicting HbCb and HhB concentration levels over a time period.

[0137] Example 29. The system of Examples 21-28, wherein one or more of the scanning mode options are configurable to select the wavelengths used for the scanning operation.

[0138] Example 30. The system of Examples 21-29, wherein one or more of the scanning mode options are configurable to select which of two or more optical sensors receive light reflected from the plurality of laser diodes. [0139] Some portions of the preceding detailed descriptions have been presented in terms of algorithms, equations and/or symbolic representations of operations on data bits within a computer memory. These algorithmic and/or equation descriptions and representations are the ways used by those skilled in the data processing arts to most effectively convey the substance of their work to others skilled in the art. An algorithm is here, and generally, conceived to be a self-consistent sequence of operations leading to a desired result. The operations are those requiring physical manipulations of physical quantities. Usually, though not necessarily, these quantities take the form of electrical or magnetic signals capable of being stored, combined, compared, and otherwise manipulated. It has proven convenient at times, principally for reasons of common usage, to refer to these signals as bits, values, elements, symbols, characters, terms, numbers, or the like.

[0140] It should be borne in mind, however, that all of these and similar terms are to be associated with the appropriate physical quantities and are merely convenient labels applied to these quantities. Unless specifically stated otherwise as apparent from the above discussion, it is appreciated that throughout the description, discussions utilizing terms such as “identifying” or “determining” or “executing” or “performing” or “collecting” or “creating” or “sending” or the like, refer to the action and processes of a computer system, or similar electronic computing device, that manipulates and transforms data represented as physical (electronic) quantities within the computer system's registers and memories into other data similarly represented as physical quantities within the computer system memories or registers or other such information storage devices.

[0141] The present disclosure also relates to an apparatus for performing the operations herein.

This apparatus may be specially constructed for the intended purposes, or it may comprise a general-purpose computer selectively activated or reconfigured by a computer program stored in the computer. Such a computer program may be stored in a computer readable storage medium, such as, but not limited to, any type of disk including floppy disks, optical disks, CD-ROMs, and magnetic-optical disks, read-only memories (ROMs), random access memories (RAMs), EPROMs, EEPROMs, magnetic or optical cards, or any type of media suitable for storing electronic instructions, each coupled to a computer system bus.

[0142] Various general-purpose systems may be used with programs in accordance with the teachings herein, or it may prove convenient to construct a more specialized apparatus to perform the method. The structure for a variety of these systems will appear as set forth in the description above. In addition, the present disclosure is not described with reference to any programming language. It will be appreciated that a variety of programming languages may be used to implement the teachings of the disclosure as described herein.

[0143] The present disclosure may be provided as a computer program product, or software, that may include a machine-readable medium having stored thereon instructions, which may be used to program a computer system (or other electronic devices) to perform a process according to the present disclosure. A machine-readable medium includes any mechanism for storing information in a form readable by a machine (e.g., a computer). For example, a machine-readable (e.g., computer-readable) medium includes a machine (e.g., a computer) readable storage medium such as a read only memory (“ROM”), random access memory (“RAM”), magnetic disk storage media, optical storage media, flash memory devices, etc.

[0144] In the foregoing disclosure, implementations of the disclosure have been described with reference to specific example implementations thereof. It will be evident that various modifications may be made thereto without departing from the broader spirit and scope of implementations of the disclosure as set forth in the following claims. The disclosure and drawings are, accordingly, to be regarded in an illustrative sense rather than a restrictive sense.

Claims

CLAIMS What is claimed is:

1. A computer-implemented method comprising: providing for display a user interface comprising a plurality of scanning mode options; receiving a selection for one of the scanning mode options, the scanning mode option configured to set operational parameters of a near infrared spectroscopy (NIRS) device; providing for display a user interface comprising a data display portion to display a data scan and a gradient scale; instructing the NIRS device to perform a scanning operation based on the selected scanning mode option, wherein the NIRS device comprises a plurality of laser diodes have different wavelengths; receiving in real time, scanning data from the NIRS device while the NIRS device performs the scanning operation; and displaying in the data display portion a graphical representation of the received scanning data according to the gradient scale.

2. The computer-implemented method of claim 1, wherein the scanning graphical representation displays a two-dimensional representation of the scanning data in the scan grid portion of the user interface corresponding to the gradient scale.

3. The computer-implemented method of claim 1, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue.

4. The computer-implemented method of claim 1, wherein the plurality of laser diodes comprises six laser diodes have the wavelengths of about 690 nanometers (nm), about 785 nm, about 808 nm, about 850 nm, about 940 nm and about 980 nm.

5. The computer-implemented method of claim 1, further comprising: providing for display a plot graph user interface comprising a plurality of plot graphs depicting aspects of the received scanning data, wherein the plot graph user interface includes graphical controls to hide or show the wavelengths being displayed in the plurality of the plot graphs.

6. The computer-implemented method of claim 1, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue.

7. The computer-implemented method of claim 1, wherein one or more of the scanning mode options are configurable to select one or more of the plurality of laser diodes used for the scanning operation.

8. The computer-implemented method of claim 1, further comprising: providing for display a user interface comprising a line graph depicting HbCh and HhB concentration levels over a time period.

9. The computer-implemented method of claim 1, wherein one or more of the scanning mode options are configurable to select the wavelengths used for the scanning operation.

10. The computer-implemented method of claim 1, wherein one or more of the scanning mode options are configurable to select which of two or more optical sensors receive light reflected from the plurality of laser diodes.

11. A system comprising one or more processors configured to perform the operations of: providing for display a user interface comprising a plurality of scanning mode options; receiving a selection for one of the scanning mode options; providing for display a user interface comprising a scan grid portion and a gradient scale; instructing a near infrared spectroscopy (NIRS) device to perform a scanning operation based on the selected scanning mode option, wherein the NIRS device comprises a plurality of laser diodes have different wavelengths; receiving in real time, scanning data from the NIRS device while the NIRS device performs the scanning operation; and displaying in the scan grid portion a graphical representation of the received scanning data according to the test type gradient scale.

12. The system of claim 11, wherein the scanning graphical representation displays a two-dimensional representation of the scanning data in the scan grid portion of the user interface corresponding to the gradient scale.

13. The system of claim 11, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue.

14. The system of claim 11, wherein the plurality of laser diodes comprises six laser diodes have the wavelengths of about 690 nanometers (nm), about 785 nm, about 808 nm, about 850 nm, about 940 nm and about 980 nm.

15. The system of claim 11, further comprising: providing for display a plot graph user interface comprising a plurality of plot graphs depicting aspects of the received scanning data, wherein the plot graph user interface includes graphical controls to hide or show the wavelengths being displayed in the plurality of the plot graphs.

16. The system of claim 11, wherein the scanning mode options comprise an option for scanning muscle tissue and an option for scanning breast tissue.

17. The system of claim 11, wherein one or more of the scanning mode options are configurable to select one or more of the plurality of laser diodes used for the scanning operation.

18. The system of claim 11, further comprising: providing for display a user interface comprising a line graph depicting HbCh and HhB concentration levels over a time period.

19. The system of claim 11, wherein one or more of the scanning mode options are configurable to select the wavelengths used for the scanning operation.

20. The system of claim 11, wherein one or more of the scanning mode options are configurable to select which of two or more optical sensors receive light reflected from the plurality of laser diodes.