WO2023200408A1 - Nanoemulsion coated-surface glove from natural rubber, nitrile, and poly isoprene for examination and surgical purposes and its manufacturing process - Google Patents
Nanoemulsion coated-surface glove from natural rubber, nitrile, and poly isoprene for examination and surgical purposes and its manufacturing process Download PDFInfo
- Publication number
- WO2023200408A1 WO2023200408A1 PCT/TH2022/000015 TH2022000015W WO2023200408A1 WO 2023200408 A1 WO2023200408 A1 WO 2023200408A1 TH 2022000015 W TH2022000015 W TH 2022000015W WO 2023200408 A1 WO2023200408 A1 WO 2023200408A1
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- WO
- WIPO (PCT)
- Prior art keywords
- nanoemulsion
- gloves
- solution
- coated surface
- weight
- Prior art date
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- 239000007908 nanoemulsion Substances 0.000 title claims abstract description 58
- 238000004519 manufacturing process Methods 0.000 title claims description 8
- 244000043261 Hevea brasiliensis Species 0.000 title description 4
- 229920003052 natural elastomer Polymers 0.000 title description 4
- 229920001194 natural rubber Polymers 0.000 title description 4
- 150000002825 nitriles Chemical class 0.000 title description 3
- 229920001195 polyisoprene Polymers 0.000 title description 2
- 230000002070 germicidal effect Effects 0.000 claims abstract description 15
- 229920000642 polymer Polymers 0.000 claims abstract description 15
- 239000003623 enhancer Substances 0.000 claims abstract description 13
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 13
- 239000000203 mixture Substances 0.000 claims abstract description 12
- 239000004816 latex Substances 0.000 claims abstract description 10
- 229920000126 latex Polymers 0.000 claims abstract description 10
- 239000003381 stabilizer Substances 0.000 claims abstract description 10
- 238000002360 preparation method Methods 0.000 claims abstract description 6
- 239000000243 solution Substances 0.000 claims description 26
- 239000011259 mixed solution Substances 0.000 claims description 14
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 230000008569 process Effects 0.000 claims description 7
- 239000000126 substance Substances 0.000 claims description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 6
- 238000000576 coating method Methods 0.000 claims description 5
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 claims description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 4
- 229920001213 Polysorbate 20 Polymers 0.000 claims description 4
- 229920001214 Polysorbate 60 Polymers 0.000 claims description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 4
- IYFATESGLOUGBX-YVNJGZBMSA-N Sorbitan monopalmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O IYFATESGLOUGBX-YVNJGZBMSA-N 0.000 claims description 4
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 claims description 4
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 claims description 4
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims description 4
- 229920000053 polysorbate 80 Polymers 0.000 claims description 4
- 239000007921 spray Substances 0.000 claims description 4
- 239000011248 coating agent Substances 0.000 claims description 3
- 239000008213 purified water Substances 0.000 claims description 3
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 claims description 2
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 claims description 2
- XZIIFPSPUDAGJM-UHFFFAOYSA-N 6-chloro-2-n,2-n-diethylpyrimidine-2,4-diamine Chemical compound CCN(CC)C1=NC(N)=CC(Cl)=N1 XZIIFPSPUDAGJM-UHFFFAOYSA-N 0.000 claims description 2
- 244000291564 Allium cepa Species 0.000 claims description 2
- 235000010167 Allium cepa var aggregatum Nutrition 0.000 claims description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 2
- 244000303040 Glycyrrhiza glabra Species 0.000 claims description 2
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 2
- 244000179886 Moringa oleifera Species 0.000 claims description 2
- 235000011347 Moringa oleifera Nutrition 0.000 claims description 2
- 244000170916 Paeonia officinalis Species 0.000 claims description 2
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 2
- 229920001219 Polysorbate 40 Polymers 0.000 claims description 2
- 229920000153 Povidone-iodine Polymers 0.000 claims description 2
- 239000005708 Sodium hypochlorite Substances 0.000 claims description 2
- NWGKJDSIEKMTRX-AAZCQSIUSA-N Sorbitan monooleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O NWGKJDSIEKMTRX-AAZCQSIUSA-N 0.000 claims description 2
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 claims description 2
- 244000269722 Thea sinensis Species 0.000 claims description 2
- 235000009754 Vitis X bourquina Nutrition 0.000 claims description 2
- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 2
- 240000006365 Vitis vinifera Species 0.000 claims description 2
- 235000014787 Vitis vinifera Nutrition 0.000 claims description 2
- 229910021536 Zeolite Inorganic materials 0.000 claims description 2
- LWZFANDGMFTDAV-BURFUSLBSA-N [(2r)-2-[(2r,3r,4s)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O LWZFANDGMFTDAV-BURFUSLBSA-N 0.000 claims description 2
- 235000019270 ammonium chloride Nutrition 0.000 claims description 2
- 229960000686 benzalkonium chloride Drugs 0.000 claims description 2
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 2
- 239000000920 calcium hydroxide Substances 0.000 claims description 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 2
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 2
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims description 2
- 235000009569 green tea Nutrition 0.000 claims description 2
- 235000011477 liquorice Nutrition 0.000 claims description 2
- 235000006408 oxalic acid Nutrition 0.000 claims description 2
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 claims description 2
- 239000000249 polyoxyethylene sorbitan monopalmitate Substances 0.000 claims description 2
- 235000010483 polyoxyethylene sorbitan monopalmitate Nutrition 0.000 claims description 2
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 claims description 2
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 claims description 2
- 229920000136 polysorbate Polymers 0.000 claims description 2
- 229940068977 polysorbate 20 Drugs 0.000 claims description 2
- 229940101027 polysorbate 40 Drugs 0.000 claims description 2
- 229940113124 polysorbate 60 Drugs 0.000 claims description 2
- 229940068968 polysorbate 80 Drugs 0.000 claims description 2
- 229960001621 povidone-iodine Drugs 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 2
- 239000001509 sodium citrate Substances 0.000 claims description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
- SUKJFIGYRHOWBL-UHFFFAOYSA-N sodium hypochlorite Chemical compound [Na+].Cl[O-] SUKJFIGYRHOWBL-UHFFFAOYSA-N 0.000 claims description 2
- 229940035044 sorbitan monolaurate Drugs 0.000 claims description 2
- 235000011067 sorbitan monolaureate Nutrition 0.000 claims description 2
- 239000001593 sorbitan monooleate Substances 0.000 claims description 2
- 235000011069 sorbitan monooleate Nutrition 0.000 claims description 2
- 229940035049 sorbitan monooleate Drugs 0.000 claims description 2
- 239000001570 sorbitan monopalmitate Substances 0.000 claims description 2
- 235000011071 sorbitan monopalmitate Nutrition 0.000 claims description 2
- 229940031953 sorbitan monopalmitate Drugs 0.000 claims description 2
- 235000018553 tannin Nutrition 0.000 claims description 2
- 229920001864 tannin Polymers 0.000 claims description 2
- 239000001648 tannin Substances 0.000 claims description 2
- 239000010457 zeolite Substances 0.000 claims description 2
- 239000000543 intermediate Substances 0.000 abstract description 2
- 238000003756 stirring Methods 0.000 abstract description 2
- 230000006641 stabilisation Effects 0.000 abstract 1
- 238000011105 stabilization Methods 0.000 abstract 1
- 239000002920 hazardous waste Substances 0.000 description 9
- 239000003921 oil Substances 0.000 description 6
- 235000019198 oils Nutrition 0.000 description 6
- 239000010781 infectious medical waste Substances 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 239000010692 aromatic oil Substances 0.000 description 3
- 239000002699 waste material Substances 0.000 description 3
- 208000025721 COVID-19 Diseases 0.000 description 2
- 241000282472 Canis lupus familiaris Species 0.000 description 2
- 229920001944 Plastisol Polymers 0.000 description 2
- 230000005183 environmental health Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 239000004999 plastisol Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 241000256113 Culicidae Species 0.000 description 1
- 244000165852 Eucalyptus citriodora Species 0.000 description 1
- 235000004722 Eucalyptus citriodora Nutrition 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- RRHGJUQNOFWUDK-UHFFFAOYSA-N Isoprene Chemical compound CC(=C)C=C RRHGJUQNOFWUDK-UHFFFAOYSA-N 0.000 description 1
- 235000019774 Rice Bran oil Nutrition 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 244000194806 Solanum sisymbriifolium Species 0.000 description 1
- 235000018724 Solanum sisymbriifolium Nutrition 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000010634 clove oil Substances 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000010642 eucalyptus oil Substances 0.000 description 1
- 229940044949 eucalyptus oil Drugs 0.000 description 1
- 239000010646 galangal oil Substances 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 239000002086 nanomaterial Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 239000002952 polymeric resin Substances 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000005871 repellent Substances 0.000 description 1
- 230000002940 repellent Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000008165 rice bran oil Substances 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000007482 viral spreading Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B42/00—Surgical gloves; Finger-stalls specially adapted for surgery; Devices for handling or treatment thereof
- A61B42/10—Surgical gloves
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/06—Coating with compositions not containing macromolecular substances
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2307/00—Characterised by the use of natural rubber
- C08J2307/02—Latex
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2309/00—Characterised by the use of homopolymers or copolymers of conjugated diene hydrocarbons
- C08J2309/02—Copolymers with acrylonitrile
- C08J2309/04—Latex
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Surgery (AREA)
- Agronomy & Crop Science (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Gloves (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
This invention presents nanoemulsion coated surface gloves which consist of germicidal long chain length polymer, disinfection enhancer, stabilizer, and intermediate. The preparation processes are mix the stabilizer and intermediate then add germicidal long chain length polymer and stir well. Next, add the disinfection enhancer into the solution and mix well. Set aside for stabilization to get the nanoemulsion solution. After that, apply the nanoemulsion solution onto the latex gloves to get the nanoemulsion coated surface gloves.
Description
Description of Invention
Title of Invention
NANOEMULSION COATED-SURFACE GLOVE FROM NATURAL RUBBER, NITRILE, AND POLY ISOPRENE FOR EXAMINATION AND SURGICAL PURPOSES AND ITS MANUFACTURING PROCESS
Technical Field
Chemistry field related to the nanoemulsion surface coated glove and its manufacturing process
Background Art
Ever since the beginning of the CO VID-19 pandemic in Thailand, related authorities are deeply concerned about waste management of the high-risk COVID-19 hazardous waste as there were reports in foreign countries of the virus spreading into the environmental system that possibly occurred due to unawareness. Therefore, the new wave of spreading may return in Thailand if the hazardous waste management is not cautiously taking into account. In Thailand under the mission of environmental health, food and water sanitary was thoughtfully planned. On the other hand, environmental health on hazardous waste is one of the most significant issues which can be classified into two sources of hazardous waste:
1. Patients who increased the amount of hazardous waste during the process of treatment. Department of Health reported that a COVID-19 patient produced approximately 2.85 kilograms of hazardous waste per bed per day
2. Hazardous waste of the early stage of state or self-quarantine. The report of the department of health showed that currently, there are 145.57 tons per day of hazardous waste in the waste disposal system or approximately 40% of hazardous waste disposal capacity meanwhile, the process of transporting the infectious waste from its origin to the Infectious waste incinerator must be prudent and circumspect. Incineration is the main infectious waste disposal method in Thailand where the waste will be incinerated with the extra high heat. Also, the report revealed that there are altogether
93 Infectious waste incinerators were 11 own by the government, 4 by private sectors, and 78 by hospitals across the country.
From the research of the patents database domestically and internationally, similar patent of inventions was found as follow:
Thai patent application no.9801002624. Its description explained the preparation of gloves that contained microorganism-protected substance in plastisol which is used as a material for gloves production. The common anti-microorganism gloves used in the food industry usually process by plastisol cold-dipping process which consisted of polymer resin, the substance that helps form plastic. However, there are some limitations of the patent as the anti-microorganism gloves are not capable of bacteria and virus protection for medical usage.
Thai petty patent no. 1703002405. The manufacturing of natural rubber grafted with polymethyl methacrylate gloves in the form of latex to increase the roughness of the surface, reducing contact between skin and gloves which resulted in the lower chance of allergy from protein in the latex. In addition, the nanosilver was added to restrain gram-positive and negative bacteria. The latex certainly is molded into various sizes, nevertheless, there is no nanoemulsion coated.
Thai petty patent no. 1803000710. Herbal nanoemulsion for dog skin contained rice bran oil, galangal oil, emulsifier, propylene glycol, and purified water. The emulsion can kill bacteria and prevent the inflammation that can be absorbed through dogs’ thick skin. However, this formula is lacking the disinfection enhancer and the germicidal long chain length polymer.
Thai petty patent no. 1603000130 related to the composition development of the nonaemulsion that being prepared without using a high-pressure homogenizer to reduce the complexity and cost in the producing process. This formula kept on the properties of 4 hours mosquitos’ repellent, users’ skin irritation-free, and good stability which enhance oil and aromatic oil scent retention. The composition of this invention contained aromatic oils such as eucalyptus citriodora and one of these aromatic oils
such as eucalyptus oil, clove oil, or wild tomato leaf extract oil together with surfactant. However, this formula is lacking the disinfection enhancer and the germicidal long chain length polymer.
Thai patent application publication no, 1601006095 described continued phase and reversible dispersed phase nanoemulsion. This nanoemulsion is in the form of water phase and oil phase as the ratio of 1:40-100:1. The water phase dispersed into a nanodroplet in the oil phase or in the opposite way. Also, the water phase contained water or aqueous solution and substance that form stability to the dissolvable organic nanostructures while the oil phase contained oil or oily solution, organic gel thickening agent, and hydrophilic surfactant that HLB >80. However, this formula is lacking the disinfection enhancer and the germicidal long chain length polymer.
Characteristic and Objective of Invention
This invention represents nanoemulsion coated surface gloves which contained germicidal long chain length polymer, disinfection enhancer, stabilizer, and intermediate. The preparation process begins with the mixture of stabilizer and intermediate, then add in the germicidal long chain length polymer and mix well. Next, add and stir well the disinfection enhancer to the solution and set it aside to stabilize. Finally, the nanoemulsion solution is ready to be used for nanoemulsion coated surface glove manufacturing.
The objectives of the invention are to develop a nanoemulsion solution for adjusting the structure of the glove s surface to contain germicidal and self-sterilize properties. More of this, the nanoemulsion spray can be applied on various surfaces and the surface of natural rubber gloves and nitrile gloves. After spray, nanochain will be released from the surface through its mechanism, the germinal membrane will lose its structure and eventually decays. The germicidal and self-sterilize properties in the nanoemulsion coated gloves resulting safety for its users.
Disclosure of Invention
Nanoemulsion coated surface gloves are film-coated natural latex which consists of latex gloves and nanoemulsion solution as the following ratio:
Glove quantity 100 unit
Nanoemulsion solution quantity 0.1-1 unit per 100 gloves
Nanoemulsion solution consists of:
Germicidal long chain length polymer percentage quantity 0.01-15 of nanoemulsion solution s weight
Disinfection enhancer percentage quantity 0.1-5 of nanoemulsion solution s weight
Stabilizer percentage quantity 0.1-5 of nanoemulsion solution s weight
Intermediate Adjust the quantity to get 100% product quantity by weight.
Germicidal long chain length polymer can be selected from single or multiple sources below:
Benzalkonium chloride, Dialkyldimethylammonium chloride, Trialkylmethyl ammonium chloride, Polysorbate 20 (Tween 20), Polysorbate 40 (Tween 40), Polysorbate 60 (Tween 60), Polysorbate 80 (Tween 80), Sorbitan monolaurate (Span 20), Sorbitan monopalmitate (Span 40), Sorbitane monostearate (Span 60), and Sorbitan monooleate (Span 80).
Disinfection enhancer can be selected from single or multiple sources below:
Sodium hypochlorite, Povidone iodine, Hydrogen peroxide, Tannin, green tea leaves extract, grape seeds extract, peony roots or flowers extract, shallot extract, drumstick tree leaves extract, and liquorice extract
The stabilizer can be selected from single or multiple sources below:
Ethylenediaminetetraacetic acid, Calcium hydroxide, Sodium hydrogen carbonate, Sodium citrate, Zeolite, and Oxalic acid
Intermediate can be selected from purified water, Ethylene glycol, Propylene glycol, Ethanol, Isopropanol, or the composition of the substance.
The preparation process of the nanoemulsion coated surface gloves as follows: a. Mix 0.1-5 by weight of the stabilizer and intermediate at 22 to 40 degrees Celsius to get the mixed solution b. Add 0.01-15 percent by weight of the germicidal long chain length polymer into step A mixed solution at 22 to 40 degrees Celsius to get the mixed solution c. Add 0.1-5 percent by weight of the disinfection enhancer into step B mixed solution at 22 to 40 degrees Celsius to get the mixed solution d. Set aside the step C mixed solution at 22 to 40 degrees Celsius for 1 to 3 hours or until the mixed solution melt. The nanoemulsion solution is ready. e. Prepare nanoemulsion solution from step D for the gloves coating process. The manufacturing process can be selected from the following:
- Dip the latex gloves in the nanoemulsion solution from step D at 22 to 40 degrees Celsius for 1 to 5 minutes then nanoemulsion coated surface gloves are ready or
- Mix the nanoemulsion solution from step D with a greasy polymer coating substance then forming on the gloves. Next, nanoemulsion coated surface gloves are ready or
- Spray the nanoemulsion solution from step D on the powder. Coated the nanoemulsion mixed powder on the latex glove then nanoemulsion coated surface gloves are ready.
Best Mode for Carrying out the Invention
Refer to the process under Disclosure of Invention
Claims
1. Nanoemulsion coated surface gloves consist of latex gloves and nanoemulsion solution as:
- Glove quantity 100 unit
- Nanoemulsion solution quantity 0.1-1 unit per 100 gloves
2. Nanoemulsion coated surface gloves refer to claim no.1. The nanoemulsion solution consists of:
Germicidal long chain length polymer percentage quantity 0.01 - 15 of nanoemulsion solution s weight
Disinfection enhancer percentage quantity 0.1-5 of nanoemulsion solution s weight
Stabilizer percentage quantity 0.1-5 of nanoemulsion solution s weight
Intermediate Adjust the quantity to get 100% product quantity by weight.
3. Nanoemulsion coated surface gloves refer to claim no.l and 2 which germicidal long chain length polymer can be selected from single or multiple sources below:
Benzalkonium chloride, Dialkyldimethylammonium chloride, Trialkylmethyl ammonium chloride, Polysorbate 20 (Tween 20), Polysorbate 40 (Tween 40), Polysorbate 60 (Tween 60), Polysorbate 80 (Tween 80), Sorbitan monolaurate (Span 20), Sorbitan monopalmitate (Span 40), Sorbitane monostearate (Span 60), and Sorbitan monooleate (Span 80)
4. Nanoemulsion coated surface gloves refer to claim no.l and 2 which disinfection enhancer can be selected from single or multiple sources below:
Sodium hypochlorite, Povidone iodine, Hydrogen peroxide, Tannin, green tea leaves extract, grape seeds extract, peony roots or flowers extract, shallot extract, drumstick tree leaves extract, and liquorice extract
5. Nanoemulsion coated surface gloves refer to claim no.l and 2 which stabilizer can be selected from single or multiple sources below:
Ethylenediaminetetraacetic acid, Calcium hydroxide, Sodium hydrogen carbonate, Sodium citrate, Zeolite, and Oxalic acid
6. Nanoemulsion coated surface gloves refer to claim no.l and 2 which intermediate can be selected from purified water, Ethylene glycol, Propylene glycol, Ethanol, Isopropanol, or the composition of the substance.
7. The preparation process of the nanoemulsion coated surface gloves refer to claim no.l as follow: a. Mix 0.1-5 by weight of the stabilizer and intermediate at 22 to 40 degrees Celsius to get the mixed solution b. Add 0.01-15 percent by weight of the germicidal long chain length polymer into step A mixed solution at 22 to 40 degrees Celsius to get the mixed solution c. Add 0.1-5 percent by weight of the disinfection enhancer into step B mixed solution at 22 to 40 degrees Celsius to get the mixed solution d. Set aside the step C mixed solution at 22 to 40 degrees Celsius for 1 to 3 hours or until the mixed solution melt. The nanoemulsion solution is ready. e. Prepare nanoemulsion solution from step D for gloves coating process to get the nanoemulsion coated surface gloves
8. The preparation process of the nanoemulsion coated surface gloves refer to claim no.6 in which the step D stated that the manufacturing process (glove coating) can be selected from the following process
- Dip the latex gloves in the nanoemulsion solution from step D at 22 to 40 degree Celsius for 1 to 5 minutes then nanoemulsion coated surface gloves are ready or
- Mix the nanoemulsion solution from step D with a greasy polymer coating substance then forming on the gloves. Next, nanoemulsion coated surface gloves are ready or
- Spray the nanoemulsion solution from step D on the powder. Coated the nanoemulsion mixed power on the latex gloves then nanoemulsion coated surface gloves are ready.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/TH2022/000015 WO2023200408A1 (en) | 2022-04-11 | 2022-04-11 | Nanoemulsion coated-surface glove from natural rubber, nitrile, and poly isoprene for examination and surgical purposes and its manufacturing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/TH2022/000015 WO2023200408A1 (en) | 2022-04-11 | 2022-04-11 | Nanoemulsion coated-surface glove from natural rubber, nitrile, and poly isoprene for examination and surgical purposes and its manufacturing process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2023200408A1 true WO2023200408A1 (en) | 2023-10-19 |
Family
ID=81841864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/TH2022/000015 WO2023200408A1 (en) | 2022-04-11 | 2022-04-11 | Nanoemulsion coated-surface glove from natural rubber, nitrile, and poly isoprene for examination and surgical purposes and its manufacturing process |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2023200408A1 (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998002624A1 (en) | 1996-07-16 | 1998-01-22 | Hoosier Group, L.L.C. | Method and apparatus for controlling expansion and contraction of trench liners |
| US20050186258A1 (en) * | 2004-02-20 | 2005-08-25 | Shiping Wang | Antimicrobial medical gloves |
| US20090143477A1 (en) * | 1999-04-28 | 2009-06-04 | Regents Of The University Of Michigan | Antimicrobial Nanoemulsion Compositions and Methods |
| WO2013167850A1 (en) * | 2012-05-11 | 2013-11-14 | Gros Robert Timothy | Method of manufacturing antimicrobial examination gloves |
| WO2014113269A1 (en) * | 2013-01-15 | 2014-07-24 | Board Of Regents, The University Of Texas System | Antimicrobial coatings |
| TH1601006095A (en) | 2016-10-07 | 2019-03-01 | ดร.พูนเดช ไกรฤทธิ์ | Nanoemulsions with continuous and reversible dispersion cycles |
-
2022
- 2022-04-11 WO PCT/TH2022/000015 patent/WO2023200408A1/en unknown
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998002624A1 (en) | 1996-07-16 | 1998-01-22 | Hoosier Group, L.L.C. | Method and apparatus for controlling expansion and contraction of trench liners |
| US20090143477A1 (en) * | 1999-04-28 | 2009-06-04 | Regents Of The University Of Michigan | Antimicrobial Nanoemulsion Compositions and Methods |
| US20050186258A1 (en) * | 2004-02-20 | 2005-08-25 | Shiping Wang | Antimicrobial medical gloves |
| WO2013167850A1 (en) * | 2012-05-11 | 2013-11-14 | Gros Robert Timothy | Method of manufacturing antimicrobial examination gloves |
| WO2014113269A1 (en) * | 2013-01-15 | 2014-07-24 | Board Of Regents, The University Of Texas System | Antimicrobial coatings |
| TH1601006095A (en) | 2016-10-07 | 2019-03-01 | ดร.พูนเดช ไกรฤทธิ์ | Nanoemulsions with continuous and reversible dispersion cycles |
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