WO2023124508A1 - 用于实验容器的加热设备及生物样本制备装置 - Google Patents

用于实验容器的加热设备及生物样本制备装置 Download PDF

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Publication number
WO2023124508A1
WO2023124508A1 PCT/CN2022/129052 CN2022129052W WO2023124508A1 WO 2023124508 A1 WO2023124508 A1 WO 2023124508A1 CN 2022129052 W CN2022129052 W CN 2022129052W WO 2023124508 A1 WO2023124508 A1 WO 2023124508A1
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Prior art keywords
heating
experimental
heating assembly
experimental container
container
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PCT/CN2022/129052
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English (en)
French (fr)
Inventor
刘南峰
黄毓锐
李凯
李成员
阳方义
黄包秀
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深圳市瑞沃德生命科技有限公司
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Publication of WO2023124508A1 publication Critical patent/WO2023124508A1/zh

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/44—Sample treatment involving radiation, e.g. heat

Definitions

  • the present application relates to the technical field of laboratory instruments, in particular to a heating device for experimental containers and a biological sample preparation device.
  • the embodiment of the present application provides a heating device for experimental containers, aiming to solve the problem of independent and stable heating of different experimental containers in the prior art.
  • a heating device for an experimental container comprising:
  • the heating component (2) is supported by the casing (1);
  • At least one temperature sensor (3) at least one temperature sensor (3) is arranged on the heating component (2);
  • the heating component (2) forms a cavity surrounding the experimental container, the first surface of which matches the outer surface of the experimental container, and clamps or releases the experimental container through deformation.
  • a biological sample preparation device including a housing, a plurality of motors, and a plurality of heating devices as described above;
  • a plurality of motors are arranged in the casing, and the drive shafts of the plurality of motors can be respectively connected with a plurality of experimental containers to drive the plurality of experimental containers to rotate, and a plurality of heating devices respectively hold the plurality of experimental containers for heating.
  • the heating assembly of the embodiment of the present application forms a cavity around the experimental container, so that the experimental container can be heated when the experimental container is clamped.
  • a temperature sensor is integrated on the heating assembly, which can monitor and adjust the heating temperature in real time.
  • the structure is compact, and the heating assembly Clamp or release the experimental container through its own deformation, which can adapt to repeated loading and disassembly without affecting other operations in the experimental container.
  • Fig. 1 is an overall schematic diagram of the heating equipment provided in Embodiment 1 of the present application;
  • Fig. 2 is a partial schematic diagram of the heating equipment provided in Embodiment 1 of the present application;
  • Fig. 3 is the schematic diagram of the experimental container that the application embodiment one provides;
  • Fig. 4 is a schematic bottom view of the heating device provided in Embodiment 1 of the present application.
  • Fig. 5 is a bottom view of the heating device provided in Embodiment 1 of the present application.
  • Fig. 6 is a schematic diagram of the biological sample preparation device provided in Example 2 of the present application.
  • Tissue is a cellular structure between cells and organs, consisting of many cells with similar shapes and intercellular matrix.
  • tissues need to be processed to prepare single cell suspensions.
  • a single-cell suspension is a biological sample in which dispersed individual cells are released due to disruption of the connections between cells in the tissue.
  • the prepared single cell suspension needs to have the characteristics of sufficient cell dispersion and high activity, that is, the connection between cells must be fully destroyed while maintaining the integrity and activity of individual cells, which is the basis for cell research.
  • the biological sample in the experimental container needs to be maintained at a specific temperature, such as 37 degrees Celsius.
  • the heating assembly of the embodiment of the present application forms a cavity around the experimental container, so that the experimental container can be heated when the experimental container is clamped.
  • a temperature sensor is integrated on the heating assembly, which can monitor and adjust the heating temperature in real time.
  • the structure is compact, and the heating assembly Clamp or release the experimental container through its own deformation, which can adapt to repeated loading and disassembly without affecting other operations in the experimental container.
  • FIG. 1 is an overall schematic diagram of a heating device provided in Embodiment 1 of the present application.
  • Fig. 2 is a partial schematic diagram of the heating device provided in Embodiment 1 of the present application.
  • Fig. 3 is a schematic diagram of the experimental container provided in Example 1 of the present application.
  • Fig. 4 is a schematic bottom view of the heating device provided in Embodiment 1 of the present application.
  • Fig. 5 is a bottom view of the heating device provided in Embodiment 1 of the present application.
  • the heating device includes a housing 1 , a heating assembly 2 and a temperature sensor 3 .
  • the experimental container for preparing single cell suspension is similar to a cylindrical test tube, consisting of an experimental container body and a cover.
  • the experimental vessel body and lid are screwed together.
  • the heating assembly 2 forms a cavity surrounding the test vessel, with a first surface matching the outer surface of the test vessel. Put the experimental container into the cavity formed by the heating component 2, the experimental container stretches the heating component 2, the heating component 2 undergoes elastic deformation, and the cavity becomes larger to clamp the experimental container; the heating component 2 returns to the original shape after releasing the experimental container, The cavity becomes smaller.
  • the experimental container can also be in other shapes, as long as the first surface of the heating component 2 matches the outer surface of the experimental container.
  • the heating component 2 is supported by the shell 1, and the shell 1 provides the necessary rigidity for the heating component 2, which is easy to grasp, isolates the external air flow to a certain extent, and reduces the influence of the air flow on the heating temperature.
  • At least one temperature sensor 3 is arranged inside or on the surface of the heating component 2 for monitoring the real-time temperature of the heating component 2, controlling the output power of the heating component 2, thereby realizing temperature feedback and adjustment functions, and maintaining the heating component 2 at a target temperature.
  • the heating assembly 2 forms a cavity surrounding the experimental container, and its first surface can match the shape of the outer surface of the experimental container.
  • the cross-section of the heating component 2 is a ring, or the cross-section of the heating component 2 is two semi-circular rings.
  • the cross section of the heating assembly 2 is a ring, there is a gap in the heating assembly 2 in the vertical direction, which is also called an opening; as another embodiment of the application, the cross section of the heating assembly 2 When there are two semi-circular rings, there is a gap at one of the two semi-circular rings, which is also called an opening.
  • the above-mentioned opening enables the heating component 2 to be elastically deformed, and the size of the cavity formed by the heating component 2 can be changed through elastic deformation to clamp and release the experimental container.
  • the heating assembly 2 When the experimental container needs to be heated, the heating assembly 2 is loaded on the experimental container, and the experimental container stretches the heating assembly 2, the heating assembly 2 undergoes elastic deformation, the formed cavity increases, and forms a press fit with the experimental container to heat the experimental container ;
  • the experimental container does not need to be heated, unplug the heating assembly 2 to release the experimental container, and the heating assembly 2 returns to its original state.
  • the heating assembly 2 When loading or unloading the heating equipment, there is friction between the heating assembly 2 and the experimental container in the vertical direction, and the heating assembly 2 is fixed in the vertical direction by the pressure plate and the screw to avoid displacement in the vertical direction.
  • the pressure plate and the screw are arranged at the above-mentioned opening to cover the opening and fix the heating assembly 2 in the vertical direction without affecting the deformation direction, which not only realizes the fixing function but also looks beautiful.
  • the heating assembly 2 includes at least one heating circuit 21 , preferably, a resistance heating circuit.
  • the heating circuit 21 is in close contact with the outer surface of the experimental container to heat the experimental container.
  • the heating assembly 2 further includes a heating ring 22, and the heating ring 22 has at least one opening in the vertical direction.
  • the heating circuit 21 is attached to the surface of the heating ring 22 .
  • the side of the heating ring 22 that is not attached with the heating circuit 21 is close to the outer surface of the experimental container, and the contact area between the heating assembly 2 and the experimental container becomes larger.
  • the heating circuit 21 generates heat, and the heating ring 22 transfers the heat emitted by the heating circuit 21 to the experimental container to heat the experimental container.
  • the heating loop 21 is a resistive heating film, which is thin and replaceable;
  • the heating ring 22 is made of a heat-conducting material with good thermal conductivity, such as an aluminum ring, and has a certain thickness.
  • other metals are mixed into the aluminum to form an aluminum alloy ring.
  • the heat emitted by the heating film is transferred to the aluminum ring and quickly distributed on the entire aluminum ring, and at the same time, it is also quickly transferred to the experimental container, making the experimental container heated more uniformly and mildly, and avoiding the local overheating of the heating film and contacting the experimental container to affect the biological samples in it .
  • Resistive heating film and aluminum ring are common materials, and the production cost is not high.
  • the aluminum ring has a certain thickness in which holes can be dug.
  • the temperature sensor 3 is arranged in the hole of the aluminum ring, monitors the real-time temperature of the aluminum ring, controls the output power of the heating film, and maintains the temperature of the aluminum ring at the target temperature. There is no need to add additional space in the structure, and the temperature can be monitored more accurately.
  • the temperature sensor 3 can also be arranged on the surface of the heating ring 22, which is not limited here.
  • the heating component 2 and the temperature sensor 3 are powered by a battery or by an external power supply.
  • the positive and negative poles required by the heating assembly 2 and the temperature sensor 3 form contacts at the bottom of the heating device to connect to the external power supply, and are drawn out from the four-wire circuit.
  • the heating assembly 2 and the temperature sensor 3 are connected to the external power supply through two pin terminals, and only two lines are required to lead out.
  • the heating assembly 2 is connected to the casing 1 through a shaft. As shown in FIG. 2 , a hole is dug on the heating ring 22 and a shaft is arranged, and the shaft is fixedly connected with the casing 1 , and the heating assembly 2 can rotate around the shaft to a limited extent relative to the casing 1 .
  • the heating device further includes thermal insulation cotton 4 .
  • the second surface of the heating element 2 is opposite to the first surface.
  • the first surface of the heating component 2 is close to the outer surface of the experimental container, and the second surface of the heating component 2 is the side away from the experimental container.
  • the thermal insulation cotton 4 is attached to the second surface of the heating component 2, which can reduce heat loss and enhance the heating effect.
  • the casing 1 includes a window 11 and a magnet 12 arranged at the bottom.
  • the heating assembly 2 clamps the experimental container, and the processing status of the biological samples in the experimental container can be observed through the window 11, and it is convenient to grasp to load or unload the heating equipment.
  • the number of windows 11 is not limited here.
  • the heating equipment is removed and placed on some metal shells, and the metal shells are adsorbed by the magnet 12, which is not easy to lose.
  • the heating assembly of the embodiment of the present application forms a cavity around the experimental container, so that the experimental container can be heated when the experimental container is clamped.
  • a temperature sensor is integrated on the heating assembly, which can monitor and adjust the heating temperature in real time.
  • the structure is compact, and the heating assembly Clamp or release the experimental container through its own deformation, which can adapt to repeated loading and disassembly without affecting other operations in the experimental container.
  • Fig. 6 is a schematic diagram of the biological sample preparation device provided in Example 2 of the present application.
  • the biological sample preparation device includes a casing, multiple motors, and multiple heating devices described in Embodiment 1.
  • the structure of the heating device is the same as that of the first embodiment, including all the features described in the first embodiment, and will not be repeated here.
  • a plurality of motors are arranged in the housing, and their drive shafts are respectively connected to a plurality of experimental containers for preparing single-cell suspensions to drive the experimental containers to rotate, and at the same time, a plurality of heating devices hold a plurality of experimental containers for heating.
  • the biological sample preparation device also includes a controller, which controls the multiple heating components 2 respectively according to the temperatures measured by the multiple temperature sensors 3, so as to stably maintain the biological samples in multiple experimental containers at the same or different specific temperatures.
  • the heating assembly of the embodiment of the present application forms a cavity around the experimental container, so that the experimental container can be heated when the experimental container is clamped.
  • a temperature sensor is integrated on the heating assembly, which can monitor and adjust the heating temperature in real time.
  • the structure is compact, and the heating assembly Clamp or release the experimental container through its own deformation, which can adapt to repeated loading and disassembly without affecting other operations in the experimental container.

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Abstract

本申请实施例提供一种加热设备，包括外壳（1）；加热组件（2），加热组件（2）由外壳（1）支撑；至少一个温度传感器（3），至少一个温度传感器（3）设置于加热组件（2）；其中，加热组件（2）形成围绕实验容器的空腔，其第一表面与实验容器的外表面相匹配，通过形变夹持实验容器或者释放实验容器。本申请实施例的加热组件形成围绕实验容器的空腔，使得夹持实验容器时可对该实验容器进行加热，加热组件上集成了温度传感器，可实时监测和调节加热温度，结构紧凑，加热组件通过自身的形变夹持或者释放实验容器，可适应反复装载和拆卸，而且不会影响实验容器内的其他操作。

Description

用于实验容器的加热设备及生物样本制备装置
本申请要求于2021年12月29日在中国专利局提交的、申请号为202111633727.X、发明名称为“用于实验容器的加热设备及生物样本制备装置”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。
技术领域
本申请涉及实验室仪器技术领域，尤其涉及一种用于实验容器的加热设备及生物样本制备装置。
 背景技术
在生物学的许多实验中，通常需要模拟生物体的体温或者在制备生物样本的过程中维持特定温度，以利于生物实验的进行。因此，需要一种加热设备，能够对单个实验容器进行加热，并且在加热的同时不会影响生物实验的其他操作。如在制备单细胞悬液时，切割、碾磨组织等操作在实验容器中进行，同时需要将每个实验容器中的生物样本维持在所需温度。在此过程中，维持的温度不能发生过大波动，否则可能会使生物样本产生变性等，而影响生物实验的结果。
 技术问题
本申请实施例提供一种用于实验容器的加热设备，旨在解决现有技术中在对不同的实验容器独立、稳定加热的问题。
 技术解决方案
第一方面，提供一种用于实验容器的加热设备，包括：
外壳（1）；
加热组件（2），加热组件（2）由外壳（1）支撑；
至少一个温度传感器（3），至少一个温度传感器（3）设置于加热组件（2）；
其中，加热组件（2）形成围绕实验容器的空腔，其第一表面与实验容器的外表面相匹配，通过形变夹持实验容器或者释放实验容器。
第二方面，提供一种生物样本制备装置，包括壳体、多个电机和多个如上描述的加热设备；
多个电机设置于外壳内，多个电机的驱动轴可分别与多个实验容器连接，驱动多个实验容器旋转，多个加热设备分别夹持多个实验容器进行加热。
 有益效果
本申请实施例的加热组件形成围绕实验容器的空腔，使得夹持实验容器时可对该实验容器进行加热，加热组件上集成了温度传感器，可实时监测和调节加热温度，结构紧凑，加热组件通过自身的形变夹持或者释放实验容器，可适应反复装载和拆卸，而且不会影响实验容器内的其他操作。
 附图说明
本申请上述的和/或附加的方面和优点从下面结合附图对实施例的描述中将变得明显和容易理解，其中：
图1是本申请实施例一提供的加热设备的总体示意图；
图2是本申请实施例一提供的加热设备的局部示意图；
图3是本申请实施例一提供的实验容器的示意图；
图4是本申请实施例一提供的加热设备的底部示意图；
图5是本申请实施例一提供的加热设备的仰视图；
图6是本申请实施例二提供的生物样本制备装置的示意图。
 本发明的实施方式
下面详细描述本申请的实施例，所述实施例的示例在附图中示出，其中自始至终相同或类似的标号表示相同或类似的模块或具有相同或类似功能的模块。下面通过参考附图描述的实施例是示例性的，仅用于解释本申请，而不能理解为对本申请的限制。相反，本申请的实施例包括落入所附加权利要求书的精神和内涵范围内的所有变化、修改和等同物。
组织是界于细胞和器官之间的细胞架构，由许多形态相似的细胞及细胞间质组成。为了对生物体进行细胞研究，需要对组织进行处理制备成单细胞悬液。单细胞悬液是指因组织中细胞之间的连接遭到破坏而释放出分散的单个细胞的一种生物样本。制备得到的单细胞悬液需具备细胞分散充分、活性高等特点，即需充分破坏细胞之间的连接而又保持单个细胞的完整和活性，是进行细胞研究的基础。在实验容器中破坏组织中细胞之间的连接的过程中，需要将实验容器中的生物样本维持在特定温度，如37摄氏度。
本申请实施例的加热组件形成围绕实验容器的空腔，使得夹持实验容器时可对该实验容器进行加热，加热组件上集成了温度传感器，可实时监测和调节加热温度，结构紧凑，加热组件通过自身的形变夹持或者释放实验容器，可适应反复装载和拆卸，而且不会影响实验容器内的其他操作。
实施例一
图1是本申请实施例一提供的加热设备的总体示意图。图2是本申请实施例一提供的加热设备的局部示意图。图3是本申请实施例一提供的实验容器的示意图。图4是本申请实施例一提供的加热设备的底部示意图。图5是本申请实施例一提供的加热设备的仰视图。结合图1至图5，该加热设备包括外壳1、加热组件2和温度传感器3。
制备单细胞悬液的实验容器类似圆柱形的试管，由实验容器本体和盖组成。实验容器本体和盖通过螺纹连接在一起。加热组件2形成围绕实验容器的空腔，其第一表面与实验容器的外表面相匹配。将实验容器放入加热组件2形成的空腔中，实验容器将加热组件2撑开，加热组件2发生弹性形变，空腔变大以夹持实验容器；加热组件2释放实验容器后恢复原状，空腔变小。实验容器也可以是其他形状，加热组件2的第一表面与实验容器的外表面相匹配即可。
加热组件2由外壳1支撑，外壳1为加热组件2提供必要的刚度，便于抓握，一定程度上隔绝外部空气流动，降低空气流动对加热温度的影响。至少一个温度传感器3设置于加热组件2的内部或者表面，用于监测加热组件2的实时温度，控制加热组件2的输出功率，从而实现温度反馈和调节功能，将加热组件2维持在目标温度。
在本申请实施例中，加热组件2形成围绕实验容器的空腔，其第一表面可匹配实验容器外表面的形状。实验容器为类似圆柱形的试管时，加热组件2的横截面为圆环，或者加热组件2的横截面为两个半圆环。作为本申请的一个实施例，加热组件2的横截面为圆环时，加热组件2在竖直方向上存在缝隙，也称为开口；作为本申请的另一实施例，加热组件2的横截面为两个半圆环时，在两个半圆环其中一邻接处存在缝隙，也称为开口。上述开口使得加热组件2可进行弹性形变，加热组件2通过弹性形变使其形成的空腔的大小可变，夹持和释放实验容器。需要加热实验容器时，加热组件2装载到实验容器上，实验容器将加热组件2撑开，加热组件2发生弹性形变，形成的空腔增大，与实验容器形成压配合，对实验容器进行加热；不需要加热实验容器时，拔下加热组件2释放实验容器，加热组件2恢复原状。装载或者卸下加热设备时，加热组件2和实验容器在竖直方向上存在摩擦力，通过压板和螺钉在竖直方向上固定加热组件2，避免其在竖直方向上发生位移。优选地，压板和螺钉设置在上述开口处，遮挡开口，在竖直方向固定加热组件2，在形变方向上不产生影响，既实现固定功能又美观。
在本申请实施例中，加热组件2包括至少一个加热回路21，优选地，为电阻加热回路。夹持实验容器时，加热回路21紧贴实验容器的外表面，对实验容器进行加热。作为本申请的一个实施例，加热组件2还包括加热环22，加热环22在竖直方向上存在至少一开口。加热回路21贴合于加热环22的表面。夹持实验容器时，加热环22未贴有加热回路21的一面紧贴实验容器的外表面，加热组件2与实验容器的接触面积变大。加热回路21发热，加热环22将加热回路21散发的热量传递至实验容器，对实验容器进行加热。优选地，如图2所示，加热回路21为电阻性的加热膜，较薄、可更换；加热环22选用导热性能良好的导热材料，如铝环，具有一定的厚度。为了提高铝环的弹性形变的能力，在铝中掺入其他的金属，形成铝合金环。加热膜散发的热量传递至铝环后迅速分布于整个铝环上，同时也迅速传递至实验容器，使得实验容器受热更均匀、更温和，避免加热膜局部过热接触实验容器而影响其中的生物样本。电阻性的加热膜和铝环都是常见的材料，制作成本不高。而且铝环具有一定的厚度，可在其中挖孔。温度传感器3设置于铝环的孔内，监测铝环的实时温度，控制加热膜的输出功率，将铝环的温度维持在目标温度。在结构上不需要增加额外的空间，而且监测温度更准确。温度传感器3也可设置于加热环22的表面，在此不做限定。
在本申请实施例中，加热组件2和温度传感器3为电池供电或者由外部电源供电。由外部电源供电时，加热组件2和温度传感器3所需的正负极在加热设备的底部形成触点以连接外部电源，由四路线路引出。为了使加热设备的结构紧凑，加热组件2和温度传感器3通过二节插针端子与外部电源连接，仅需两路线路引出。加热组件2通过触点连接外部电源时，为了克服实验容器、外部电源和加热组件2的相对位置产生的误差。在本申请实施例中，加热组件2通过轴与外壳1连接。如图2所示，在加热环22上挖孔并设置轴，该轴与外壳1固定连接，加热组件2相对于外壳1可绕轴有限度地转动。
在本申请实施例中，加热设备还包括保温棉4。加热组件2的第二表面与第一表面相对。夹持实验容器时，加热组件2的第一表面紧贴实验容器的外表面，加热组件2的第二表面为背离实验容器的一侧。保温棉4贴合于加热组件2的第二表面，可减少热量流失，增强加热效果。
在本申请实施例中，外壳1包括视窗11和设置在底部的磁铁12。需要加热实验容器时，加热组件2夹持实验容器，透过该视窗11可观察实验容器中生物样本的处理状态，而且便于抓握以装载或者卸下加热设备。视窗11的数量在此不做限定。不需要加热实验容器时，卸下加热设备放置在一些金属壳体上，通过磁铁12吸附金属壳体，不易丢失。
本申请实施例的加热组件形成围绕实验容器的空腔，使得夹持实验容器时可对该实验容器进行加热，加热组件上集成了温度传感器，可实时监测和调节加热温度，结构紧凑，加热组件通过自身的形变夹持或者释放实验容器，可适应反复装载和拆卸，而且不会影响实验容器内的其他操作。
实施例二
图6是本申请实施例二提供的生物样本制备装置的示意图。如图6所示，生物样本制备装置包括壳体、多个电机和多个实施例一描述的加热设备。在本申请实施例中，加热设备的结构与实施例一相同，包括在实施例一中描述的全部特征，在此不再赘述。
在本申请实施例中，多个电机设置于壳体内，其驱动轴分别与多个制备单细胞悬液的实验容器连接，驱动实验容器旋转，同时多个加热设备分别夹持多个实验容器进行加热。生物样本制备装置还包括控制器，控制器根据多个温度传感器3测得的温度分别控制多个加热组件2，可将多个实验容器中的生物样本稳定维持在相同或者不同的特定温度。
本申请实施例的加热组件形成围绕实验容器的空腔，使得夹持实验容器时可对该实验容器进行加热，加热组件上集成了温度传感器，可实时监测和调节加热温度，结构紧凑，加热组件通过自身的形变夹持或者释放实验容器，可适应反复装载和拆卸，而且不会影响实验容器内的其他操作。
尽管上面已经示出和描述了本申请的实施例，可以理解的是，上述实施例是示例性的，不能理解为对本申请的限制，本领域的普通技术人员在本申请的范围内可以对上述实施例进行变化、修改、替换和变型。

Claims (10)

  1. 用于实验容器的加热设备，其特征在于，包括：
    外壳（1）；
    加热组件（2），所述加热组件（2）由所述外壳（1）支撑；
    至少一个温度传感器（3），所述至少一个温度传感器（3）设置于所述加热组件（2）；
    其中，所述加热组件（2）形成围绕实验容器的空腔，其第一表面与所述实验容器的外表面相匹配，通过形变夹持所述实验容器或者释放所述实验容器。
  2. 根据权利要求1所述的加热设备，其特征在于，所述加热组件（2）包括至少一个加热回路（21）。
  3. 根据权利要求2所述的加热设备，其特征在于，所述加热组件（2）还包括加热环（22），所述至少一个加热回路（21）贴合于所述加热环（22）的表面。
  4. 根据权利要求3所述的加热设备，其特征在于，所述至少一个温度传感器（3）设置于所述加热环（22）的内部或者表面。
  5. 根据权利要求1-4任一项所述的加热设备，其特征在于，所述加热组件（2）通过轴与所述外壳（1）连接。
  6. 根据权利要求1-4任一项所述的加热设备，其特征在于，还包括保温棉（4），所述保温棉（4）贴合于所述加热组件（2）的第二表面。
  7. 根据权利要求1-4任一项所述的加热设备，其特征在于，所述加热组件（2）和所述至少一个温度传感器（3）通过二节插针端子与外部电源连接。
  8. 根据权利要求1-4任一项所述的加热设备，其特征在于，所述外壳（1）包括视窗（11）。
  9. 生物样本制备装置，其特征在于，包括壳体、多个电机和多个如权利要求1-8任一项所述的加热设备；
    所述多个电机设置于所述壳体内，所述多个电机的驱动轴可分别与多个实验容器连接，驱动所述多个实验容器旋转，所述多个加热设备分别夹持所述多个实验容器进行加热。
  10. 根据权利要求9所述的生物样本制备装置，其特征在于，还包括控制器，所述控制器分别控制所述多个加热设备对所述多个实验容器进行加热。
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CN113567213A (zh) * 2021-08-13 2021-10-29 深圳市瑞沃德生命科技有限公司 用于实验容器的加热设备及生物样本制备装置
CN114354312A (zh) * 2021-12-29 2022-04-15 深圳市瑞沃德生命科技有限公司 用于实验容器的加热设备及生物样本制备装置

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CN102600921A (zh) * 2011-01-24 2012-07-25 美天施生物科技有限责任公司 用于圆柱形实验室器皿的加热设备
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