WO2023109706A1 - 一种自动化行为测试装置 - Google Patents

一种自动化行为测试装置 Download PDF

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Publication number
WO2023109706A1
WO2023109706A1 PCT/CN2022/138190 CN2022138190W WO2023109706A1 WO 2023109706 A1 WO2023109706 A1 WO 2023109706A1 CN 2022138190 W CN2022138190 W CN 2022138190W WO 2023109706 A1 WO2023109706 A1 WO 2023109706A1
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Prior art keywords
bottle
metal
metal ring
fixed panel
testing device
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PCT/CN2022/138190
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English (en)
French (fr)
Inventor
孟志强
鲍进
朱英杰
刘畅
周涛
黄天文
陈祖昕
陈波
周魁魁
徐薇
张淑雯
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深圳先进技术研究院
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Publication of WO2023109706A1 publication Critical patent/WO2023109706A1/zh

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K29/00—Other apparatus for animal husbandry
    • A01K29/005—Monitoring or measuring activity, e.g. detecting heat or mating
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K7/00—Watering equipment for stock or game
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81—Aquaculture, e.g. of fish

Definitions

  • the present application relates to the field of animal behavior measurement, in particular to an automatic behavior testing device.
  • the two-bottle test is a widely used behavioral testing method, as the name suggests, the test requires two identical water bottles filled with different solutions, both presented to the thirsty animal simultaneously (the positions of the two bottles are alternated periodically) , the animal will try the solutions in the two water bottles, and if it prefers one of them, it will drink the solution first. By measuring the remaining amount of the two water bottle solutions within a certain period of time, the animal's preference for different solutions is detected degree. Behaviors such as depression and addiction can be studied based on the characteristics of the solution contained in the bottle. For example, when two water bottles contained a sucrose solution and water, animals generally preferred to drink the sucrose solution, whereas animals that were depressed, dysgeusic, or anhedonic did not develop a preference for the sucrose solution.
  • the existing double-bottle test is mainly used in the research of small animals such as rodents. Usually, it is necessary to manually place the water bottle and weigh the amount of the solution, and cannot automatically detect the drinking amount, drinking time and frequency of the animal. In large animals, however, there is no associated automation.
  • the present application provides an automatic behavior testing device, which realizes automatic detection of the drinking amount, drinking time and times of animals by arranging a pressure sensor and a counting component at the bottom of the drinking bottle.
  • the application provides an automatic behavior testing device, including a fixed panel and a data acquisition module, the fixed panel is provided with a plurality of drinking bottles placed upside down, each of the drinking bottles is provided with a useful
  • the counting part is used to monitor the number of times animals drink water.
  • the counting part includes a metal bottle mouth and a metal ring.
  • the metal bottle mouth communicates with the inner cavity of the drinking bottle.
  • One side of the metal ring away from the mouth of the metal bottle is connected to the fixed panel through an insulating member, and the metal ring is also connected to the data acquisition module through a wire; the data acquisition module is used to The data transmitted by the wire records how often and when the animals drink.
  • the fixed panel is provided with a plurality of brackets, and the brackets correspond to the drinking water bottles one by one, and the drinking water bottles are placed upside down on the brackets, and the brackets are provided with pressure indicators for real-time monitoring of the pressure on the upper surface of the brackets.
  • a pressure sensor the pressure sensor is electrically connected to the data acquisition module;
  • the data acquisition module is also used for receiving the pressure data transmitted by the pressure sensor in real time and converting it into water bottle weight data.
  • bracket is provided with a through hole for the mouth of the metal bottle to pass through.
  • the pressure sensor is a thin film pressure sensor.
  • one side of the metal ring away from the metal bottle mouth is embedded into the fixed panel through a rubber pad.
  • the fixing panel is provided with a slot and/or a buckle capable of fixing the fixing panel on the cage body.
  • each of the drinking water bottles is fixed on the fixed panel by buckles.
  • the number of drinking water bottles is two.
  • the present application has the following beneficial effects: the device of the present application can be applied to the behavior test experiments of large animals, and is compatible with most large animal cages. While placing the water bottle more conveniently, it can automatically record the number and time of the animals drinking each bottle of solution, the drinking amount, and the remaining solution amount.
  • the automatic weighing device based on the thin-film pressure sensor can monitor the weight of the water bottle in real time, avoiding the loss and error of pouring the solution into the measuring cylinder for many times.
  • the data of drinking times and time is automatically collected, which cannot be recorded by manual methods, so it provides data that could not be obtained before, and enriches the dimension of data.
  • FIG. 1 is a schematic structural diagram of the automated behavior testing device of the present application.
  • connection should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection. Connected, or integrally connected; For those of ordinary skill in the art, the specific meanings of the above terms in this application can be understood in specific situations.
  • first and second are used for descriptive purposes only, and cannot be interpreted as indicating or implying relative importance or implicitly specifying the quantity of indicated technical features. Thus, a feature defined as “first” and “second” may explicitly or implicitly include one or more of these features. In the description of the present application, unless otherwise specified, "plurality" means two or more.
  • the present application provides an automated behavior testing device, which can be applied to related research on large experimental animals.
  • the device includes a fixed panel 10, a data acquisition module, and a plurality of drinking water bottles 2 placed upside down, preferably two drinking water bottles 2.
  • the data acquisition module includes a data connector 4 and data acquisition software, and the data connector 4 is fixed on the fixed panel 10 .
  • the drinking water bottle 2 can be arranged on one side of the fixed panel 10 through the second buckle 3 as shown in FIG. 1 , or by bonding or the like.
  • the bottom of each drinking bottle 2 is provided with a counting part for monitoring the number of times the animal drinks water.
  • the counting part includes a metal bottle mouth 6 and a metal ring 7, and one end of the metal bottle mouth 6 passes through the bottle cap and the inner cavity of the drinking bottle 2 Connected, that is, the fluid in the drinking water bottle 2 can flow out through the metal bottle mouth 6, and the outer surface of the metal bottle mouth 6 is in close contact with the metal ring 7.
  • the metal ring 7 is a metal ring, the central axis of the metal ring is perpendicular to the axis of the metal bottle mouth 6, and the side of the metal ring 7 away from the metal bottle mouth 6 is embedded in the fixed panel through a rubber pad 8, and the metal ring 7 is also Connect with the data connector 4 through wires.
  • the fixed panel 10 is provided with a plurality of brackets 5 for placing drinking water bottles 2.
  • the brackets 5 correspond to the drinking water bottles 2 one by one.
  • the drinking water bottles 2 are placed upside down on the brackets 5.
  • the pressure sensor of the pressure the pressure sensor transmits the data to the data joint 4 through the data line.
  • the pressure sensor is a thin-film pressure sensor, and the bracket 5 is provided with a through hole for the metal bottle mouth 6 to pass through.
  • the lower part of the fixed panel 10 is provided with a draw-in groove 9 matched with the cage, and the left and right sides of the top are provided with the first buckle 1 matched with the cage. Groove 9 is fixed with cage.
  • the data acquisition software can record the number and time of animal drinking water according to the data transmitted by the wire of the metal ring 7; it can also convert the pressure data received in real time into water bottle weight data.
  • the conversion formula between water bottle weight and pressure is obtained after pre-calibration of water bottles with different weights.
  • the working principle of the present application is as follows: the drinking bottle 2 is placed upside down on the support 5, and the pressure sensor on the support 5 can monitor the pressure on the upper surface of the support 5 in real time, and transmit the pressure data to the data connector 4 through the data line. , the data acquisition software converts the pressure data into the weight data of the drinking water bottle 2 after receiving it.
  • the metal bottle mouth 6 of the drinking bottle 2 is in close contact with the metal ring, and the metal ring is connected to the wire and embedded in the water bottle fixing panel by the rubber pad 8 . Therefore, the metal bottle mouth 6 is insulated from the fixed panel 10, and when the animal licks the metal bottle mouth 6, the capacitance on the surface of the bottle mouth changes, and the change of this capacitance can be transmitted to the data connector 4 through the wire of the metal ring , and then use data acquisition software to record the number of times animals drink water in real time.

Abstract

一种自动化行为测试装置，包括固定面板（10）和数据采集模块，固定面板（10）上设置有多个倒立放置的饮水瓶（2），每个饮水瓶（2）的下方均设置有用于监测动物喝水次数的计数部件，计数部件包括金属瓶嘴（6）和金属环件（7），金属瓶嘴（6）与饮水瓶（2）的内腔连通，金属瓶嘴（6）的外侧面与金属环件（7）相接触，金属环件（7）背离金属瓶嘴（6）的一个侧面通过绝缘件与固定面板（10）连接，金属环件（7）还通过导线与数据采集模块连接；数据采集模块用于根据金属环件（7）导线传输的数据记录动物饮水的次数和时间。

Description

一种自动化行为测试装置 技术领域
本申请涉及动物行为测定领域，尤其涉及一种自动化行为测试装置。
 背景技术
双瓶测试是一种广泛应用的行为测试方法，顾名思义，测试需要两个相同的水瓶，水瓶中装有不同的溶液，两个水瓶同时呈现给饥渴的动物（两个瓶子的位置定期交替），动物将尝试两个水瓶中的溶液，如果更喜欢其中一种就会优先饮用其中的溶液，通过在一定的时间内测量两个水瓶种溶液的剩余量，从而来检测动物对不同溶液的偏好程度。根据瓶中所装溶液的特征可以研究抑郁、成瘾等行为。例如，当两个水瓶种分别盛有蔗糖溶液和水的时候，动物通常会优先选择引用蔗糖溶液，而抑郁的动物、味觉异常的动物或快感缺失的动物则不会形成对蔗糖溶液的偏好。
 技术问题
现有的双瓶测试主要应用于啮齿类等小动物的相关研究，通常需要手动的放置水瓶及称量溶液的量，不能自动检测动物的饮用量以及饮用时间和次数等。而在大动物中，也没有相关的自动化装置。
 技术解决方案
本申请提供一种自动化行为测试装置，通过在饮水瓶的底部设置压力传感器和计数部件，实现了自动检测动物的饮用量、饮用时间和次数。
为达到上述目的，本申请提供了一种自动化行为测试装置，包括固定面板和数据采集模块，所述固定面板上设置有多个倒立放置的饮水瓶，每个所述饮水瓶的下方均设置有用于监测动物喝水次数的计数部件，所述计数部件包括金属瓶嘴和金属环件，所述金属瓶嘴与饮水瓶的内腔连通，所述金属瓶嘴的外侧面与所述金属环件相接触，所述金属环件背离所述金属瓶嘴的一个侧面通过绝缘件与固定面板连接，所述金属环件还通过导线与数据采集模块连接；所述数据采集模块用于根据金属环件导线传输的数据记录动物饮水的次数和时间。
进一步地，所述固定面板上设置有多个支架，所述支架与所述饮水瓶一一对应，所述饮水瓶倒立放置在支架上，支架上设置有用于实时监测支架上表面所受压力的压力传感器，所述压力传感器与数据采集模块电连接；
所述数据采集模块还用于实时接收压力传感器传输的压力数据并将其转化为水瓶重量数据。
进一步地，所述支架上开设有供金属瓶嘴穿过的通孔。
进一步地，所述压力传感器为薄膜压力传感器。
进一步地，所述金属环件背离所述金属瓶嘴的一个侧面通过橡胶垫嵌入固定面板。
进一步地，所述固定面板上设置有能够将固定面板固定在笼体上的卡槽和/或卡扣。
进一步地，所述每个所述饮水瓶的均通过卡扣固定在固定面板上。
进一步地，所述饮水瓶的数量为两个。
 有益效果
本申请相比现有技术具有以下有益效果：本申请装置可应用于大动物的行为测试实验中，兼容大部分大动物笼具。在更方便的放置水瓶的同时，可自动记录动物对每瓶溶液的饮用次数和时间、饮用量、剩余溶液量。基于薄膜压力传感器的自动称重装置可实时监测水瓶的重量，避免多次将溶液倒入量筒称量的损耗和误差。饮水次数和时间数据自动采集，这些数据是手动方法所不能记录到的，因此提供了在此之前不可能得到的数据，丰富了数据的维度。
 附图说明
为了更清楚地说明本申请实施例或现有技术中的技术方案，下面将对实施例或现有技术描述中所需要使用的附图作简单地介绍，显而易见地，下面描述中的附图仅仅是本申请的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1为本申请自动化行为测试装置的结构示意图。
图中，1-第一卡扣，2-饮水瓶，3-第二卡扣，4-数据接头，5-支架，6-金属瓶嘴，7-金属环件，8-橡胶垫，9-卡槽，10-固定面板。
 本发明的实施方式
下面将结合本申请实施例中的附图，对本申请实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本申请一部分实施例，而不是全部的实施例。基于本申请中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本申请保护的范围。
在本申请的描述中，需要理解的是，术语“中心”、“上”、“下”、“前”、“后”、“左”、“右”、“竖直”、“水平”、“顶”、“底”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本申请和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本申请的限制。
在本申请的描述中，需要说明的是，除非另有明确的规定和限定，术语“安装”、“相连”、“连接”应做广义理解，例如，可以是固定连接，也可以是可拆卸连接，或一体地连接；对于本领域的普通技术人员而言，可以具体情况理解上述术语在本申请中的具体含义。
术语“第一”、“第二”仅用于描述目的，而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量。由此，限定有“第一”、“第二”的特征可以明示或者隐含地包括一个或者更多个该特征。在本申请的描述中，除非另有说明，“多个”的含义是两个或两个以上。
参照图1，本申请提供了一种自动化行为测试装置，可应用于大型实验动物的相关研究。装置包括固定面板10、数据采集模块、多个倒立放置的饮水瓶2，饮水瓶2优选为两个。数据采集模块包括数据接头4和数据采集软件，数据接头4固定在固定面板10上。
饮水瓶2可通过如图1所示的第二卡扣3设置在固定面板10的一侧，也可通过粘接等方式。每个饮水瓶2的下方均设置有用于监测动物喝水次数的计数部件，计数部件包括金属瓶嘴6和金属环件7，金属瓶嘴6的一端穿过瓶盖与饮水瓶2的内腔连通，即饮水瓶2内的流体可通过金属瓶嘴6流出，金属瓶嘴6的外侧面与金属环件7密切接触。金属环件7为金属圆环，金属圆环的中心轴线与金属瓶嘴6的轴线相垂直，金属环件7远离金属瓶嘴6的一侧通过橡胶垫8嵌入固定面板，金属环件7还通过导线与数据接头4连接。
固定面板10上设置有多个用于放置饮水瓶2的支架5，支架5与饮水瓶2一一对应，饮水瓶2倒立放置在支架5上，支架5上设置有用于实时监测支架5上表面所受压力的压力传感器，压力传感器通过数据线将数据输送至数据接头4。压力传感器为薄膜压力传感器，支架5上开设有供金属瓶嘴6穿过的通孔。固定面板10的下部开设有与笼具相配合的卡槽9，上部的左右两边设置有设有与笼具相配合的第一卡扣1，在实验时，可通过第一卡扣1和卡槽9与笼具固定。
数据采集软件能够根据金属环件7的导线传输的数据记录动物饮水的次数和时间；还能够将实时接收的压力数据转化为水瓶重量数据。水瓶重量与压力之间的转换公式是通过不同重量的水瓶进行事先矫准后得到的。
本申请的工作原理如下：饮水瓶2倒立放置在支架5上，支架5上的压力传感器就可以实时监测支架5上表面所受压力，并将压力传数据通过数据线将数据输送至数据接头4，数据采集软件接收到压力数据后转化为饮水瓶2的重量数据。
饮水瓶2的金属瓶嘴6与金属圆环密切接触，金属圆环与导线相连并通过橡胶垫8嵌入水瓶固定面板。因此，金属瓶嘴6与固定面板10是绝缘的，当动物舔舐金属瓶嘴6时，瓶嘴表面的电容发生了改变，这种电容的改变可以通过金属圆环的导线输送至数据接头4，再利用数据采集软件实时记录动物喝水次数。
以上，仅为本申请的具体实施方式，但本申请的保护范围并不局限于此，任何在本申请揭露的技术范围内的变化或替换，都应涵盖在本申请的保护范围之内。因此，本申请的保护范围应该以权利要求的保护范围为准。

Claims (8)

  1. 一种自动化行为测试装置，其特征在于，包括固定面板和数据采集模块，所述固定面板上设置有多个倒立放置的饮水瓶，每个所述饮水瓶的下方均设置有用于监测动物喝水次数的计数部件，所述计数部件包括金属瓶嘴和金属环件，所述金属瓶嘴与饮水瓶的内腔连通，所述金属瓶嘴的外侧面与所述金属环件相接触，所述金属环件背离所述金属瓶嘴的一个侧面通过绝缘件与固定面板连接，所述金属环件还通过导线与数据采集模块连接；所述数据采集模块用于根据金属环件导线传输的数据记录动物饮水的次数和时间。
  2. 根据权利要求1所述的一种自动化行为测试装置，其特征在于，所述固定面板上设置有多个支架，所述支架与所述饮水瓶一一对应，所述饮水瓶倒立放置在支架上，支架上设置有用于实时监测支架上表面所受压力的压力传感器，所述压力传感器与数据采集模块电连接；
    所述数据采集模块还用于实时接收压力传感器传输的压力数据并将其转化为水瓶重量数据。
  3. 根据权利要求2所述的一种自动化行为测试装置，其特征在于，所述支架上开设有供金属瓶嘴穿过的通孔。
  4. 根据权利要求2所述的一种自动化行为测试装置，其特征在于，所述压力传感器为薄膜压力传感器。
  5. 根据权利要求1所述的一种自动化行为测试装置，其特征在于，所述绝缘件为橡胶垫，所述金属环件背离所述金属瓶嘴的一个侧面通过橡胶垫嵌入固定面板。
  6. 根据权利要求1所述的一种自动化行为测试装置，其特征在于，所述固定面板上设置有能够将固定面板固定在笼体上的卡槽和/或卡扣。
  7. 根据权利要求1或2所述的一种自动化行为测试装置，其特征在于，所述每个所述饮水瓶的均通过卡扣固定在固定面板上。
  8. 根据权利要求1所述的一种自动化行为测试装置，其特征在于，所述饮水瓶的数量为两个。
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