WO2023080725A1 - Composition comprenant cassia mimosoides var. nomame en tant que principe actif pour favoriser ou améliorer le métabolisme énergétique - Google Patents

Composition comprenant cassia mimosoides var. nomame en tant que principe actif pour favoriser ou améliorer le métabolisme énergétique Download PDF

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Publication number
WO2023080725A1
WO2023080725A1 PCT/KR2022/017277 KR2022017277W WO2023080725A1 WO 2023080725 A1 WO2023080725 A1 WO 2023080725A1 KR 2022017277 W KR2022017277 W KR 2022017277W WO 2023080725 A1 WO2023080725 A1 WO 2023080725A1
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WO
WIPO (PCT)
Prior art keywords
extract
composition
var
energy metabolism
nomame
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Application number
PCT/KR2022/017277
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English (en)
Korean (ko)
Inventor
이선희
신유경
김현재
류제식
안혜신
나창선
윤영서
허소원
정경숙
이경태
Original Assignee
코스맥스바이오 주식회사
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Publication of WO2023080725A1 publication Critical patent/WO2023080725A1/fr

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/3262Foods, ingredients or supplements having a functional effect on health having an effect on blood cholesterol
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/328Foods, ingredients or supplements having a functional effect on health having effect on glycaemic control and diabetes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/332Promoters of weight control and weight loss
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00Food ingredients
    • A23V2250/20Natural extracts
    • A23V2250/21Plant extracts
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00Processes
    • A23V2300/14Extraction

Definitions

  • Another aspect provides a health functional food composition for preventing or improving obesity, which includes an extract of Cassia mimosoides var. nomame as an active ingredient.
  • the metabolic disease may be one or more selected from the group consisting of fatty liver, diabetes, hypertension, hyperlipidemia, hypercholesterolemia, dyslipidemia, and arteriosclerosis.
  • Preparations metabolic preparations, diabetes concomitant medicines, tissue regeneration medicines, chlorophyll preparations, pigment preparations, tumor medicines, tumor treatment agents, radiopharmaceuticals, tissue cell diagnostic agents, tissue cell therapy agents, antibiotics preparations, antiviral agents, complex antibiotics preparations, chemicals Therapeutic agents, vaccines, toxins, toxoids, antitoxins, leptospira serum, blood products, biological agents, analgesics, immunogenic molecules, antihistamines, allergy medications, non-specific immunogenic agents, anesthetics, stimulants, psychoactive agents, small molecule compounds, nucleic acids, It may include aptamers, antisense nucleic acids, oligonucleotides, peptides, siRNAs, and micro RNAs.
  • the 30% alcohol extract contained in the composition was prepared by the following process. First, domestically grown tea grass was purchased, washed thoroughly with distilled water, and then completely dried in a cool place without sunlight until there was no change in weight. Then, after preparing 30 kg of 30% fermented alcohol (30 times, w/w) to the completely dried dried product, 1 kg of the dried product was added. At this time, the mixing ratio of the dry matter and 30% fermented alcohol was 30 times the weight ratio. Next, 30% fermented alcohol mixed with the dried product was put in a constant temperature water bath and stirred and extracted at 80 ° C. for 5 hours. The extracted sample was filtered and concentrated under reduced pressure to obtain a yellow-brown water-soluble powder.
  • 3T3-L1 was attached to a 96-well plate at a concentration of 1.0 X 10 4 cells/well for 24 hours to stabilize. Thereafter, the hot-water extract and 30% alcohol extract of green tea plant were exchanged with the medium treated with the sample for each concentration and cultured for 24 hours. Then, the degree of cell viability was measured by MTT assay.
  • a nutritious cream was prepared according to the composition shown in Table 9 below according to a conventional method.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Rheumatology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Birds (AREA)
  • Polymers & Plastics (AREA)
  • Pain & Pain Management (AREA)
  • Medical Informatics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La présente invention concerne une composition comprenant un extrait de Cassia mimosoides var. nomame en tant que principe actif pour favoriser ou améliorer le métabolisme énergétique. Selon un aspect, une composition comprenant Cassia mimosoides var. nomame en tant que principe actif peut favoriser ou améliorer le métabolisme énergétique pour présenter l'effet consistant à supprimer l'accumulation des lipides ou à réduire la graisse corporelle, ce qui permet de trouver des applications avantageuses dans le traitement de l'obésité et des maladies métaboliques.
PCT/KR2022/017277 2021-11-04 2022-11-04 Composition comprenant cassia mimosoides var. nomame en tant que principe actif pour favoriser ou améliorer le métabolisme énergétique WO2023080725A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2021-0150886 2021-11-04
KR20210150886 2021-11-04

Publications (1)

Publication Number Publication Date
WO2023080725A1 true WO2023080725A1 (fr) 2023-05-11

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PCT/KR2022/017277 WO2023080725A1 (fr) 2021-11-04 2022-11-04 Composition comprenant cassia mimosoides var. nomame en tant que principe actif pour favoriser ou améliorer le métabolisme énergétique

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KR (1) KR20230065192A (fr)
WO (1) WO2023080725A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11187843A (ja) * 1997-12-25 1999-07-13 Lotte Co Ltd 肥満改善用の飲食組成物およびこれを含有する飲食物
KR100331064B1 (ko) * 1994-06-23 2002-10-25 가부시끼가이샤 롯데 혈중지질강하제를함유하는가공음식품
JP2003171295A (ja) * 2001-12-06 2003-06-17 Sakamoto Yakusoen:Kk 高脂血症治療剤
JP2005343808A (ja) * 2004-06-01 2005-12-15 Gotoo Corporation:Kk 肥満及び生活習慣病の抑制剤
KR20090025638A (ko) * 2007-09-06 2009-03-11 주식회사 디에이치피코리아 항비만용 약제학적 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101509055B1 (ko) 2012-11-19 2015-04-08 대한민국 비만 및 지질관련 대사성 질환의 예방 및 치료용 조성물 및 그 제조방법

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100331064B1 (ko) * 1994-06-23 2002-10-25 가부시끼가이샤 롯데 혈중지질강하제를함유하는가공음식품
JPH11187843A (ja) * 1997-12-25 1999-07-13 Lotte Co Ltd 肥満改善用の飲食組成物およびこれを含有する飲食物
JP2003171295A (ja) * 2001-12-06 2003-06-17 Sakamoto Yakusoen:Kk 高脂血症治療剤
JP2005343808A (ja) * 2004-06-01 2005-12-15 Gotoo Corporation:Kk 肥満及び生活習慣病の抑制剤
KR20090025638A (ko) * 2007-09-06 2009-03-11 주식회사 디에이치피코리아 항비만용 약제학적 조성물

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