WO2023057611A1 - Bioréacteur - Google Patents

Bioréacteur Download PDF

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Publication number
WO2023057611A1
WO2023057611A1 PCT/EP2022/077902 EP2022077902W WO2023057611A1 WO 2023057611 A1 WO2023057611 A1 WO 2023057611A1 EP 2022077902 W EP2022077902 W EP 2022077902W WO 2023057611 A1 WO2023057611 A1 WO 2023057611A1
Authority
WO
WIPO (PCT)
Prior art keywords
light
container
bioreactor
medium
plate
Prior art date
Application number
PCT/EP2022/077902
Other languages
German (de)
English (en)
Inventor
Thomas Emde
Christoph Petersen
Original Assignee
Lightpat Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lightpat Gmbh filed Critical Lightpat Gmbh
Publication of WO2023057611A1 publication Critical patent/WO2023057611A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/02—Photobioreactors
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H4/00—Plant reproduction by tissue culture techniques ; Tissue culture techniques therefor
    • A01H4/005—Methods for micropropagation; Vegetative plant propagation using cell or tissue culture techniques
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/34—Internal compartments or partitions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M31/00—Means for providing, directing, scattering or concentrating light
    • C12M31/08—Means for providing, directing, scattering or concentrating light by conducting or reflecting elements located inside the reactor or in its structure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M31/00—Means for providing, directing, scattering or concentrating light
    • C12M31/10—Means for providing, directing, scattering or concentrating light by light emitting elements located inside the reactor, e.g. LED or OLED

Definitions

  • the present invention relates to a bioreactor which comprises a container which accommodates phototrophic organisms, microorganisms or plants, wherein at least one light source which emits light in frequencies suitable for the organisms, microorganisms or plants is assigned to the bioreactor.
  • a bioreactor is known from EP 3 167 042 B1, which is used, for example, for the phototrophic cultivation of algae or cyanobacteria.
  • species of algae are known to produce astaxanthin. Astaxanthin is a xanthophyll colourant, a powerful antioxidant and is considered a valuable food colourant, approved by the European Commission under the designation E161j. Astaxanthin is also added to fish feed in salmon farming and is required in relatively large quantities.
  • Lighting systems are also used in plant breeding, for example in the cultivation of tomato plants in greenhouses, with LED lights or alternatively also high-pressure sodium lights being used here as a rule.
  • the procedure to date has been to arrange one or, as a rule, several lighting devices or lamps at a distance from the bioreactor or from the plants, so that the Light from the lighting device is emitted onto the bioreactor or the plant. If microorganisms that are in a suitable nutrient medium inside a bioreactor are irradiated with light from such a light source from outside the bioreactor, the lighting device must be at a certain distance from the bioreactor and the light must also penetrate the wall of the bioreactor , so that light losses occur through light scattering, reflection and absorption.
  • light sources such as LEDs generate a high proportion of thermal energy, which requires a corresponding distance from the bioreactor or heat has to be dissipated become. Due to the loss of light and the conversion into heat energy, such a system is not optimized in terms of energy, since only a proportion of the energy used is used for the light that ultimately irradiates the microorganisms.
  • the necessary distance between the lighting device and the bioreactor that is irradiated with light leads to the fact that, in the case of larger systems, a considerable amount of space is required, which significantly exceeds the space required by the bioreactors themselves.
  • a light that is as uniform as possible, ie homogeneous is advantageous for the illumination of microorganisms and plants.
  • the object of the invention is to provide a bioreactor of the type mentioned at the outset, which brings the light source closer to the irradiated microorganisms or plants, so that the light is used more effectively and energy is thus also saved.
  • At least partial areas of the container itself or of built-in components within the container are designed to be self-luminous and consist either of a light-conducting, transparent or translucent material or at least comprise a flat or punctiform light source integrated into the partial area of the container.
  • the solution according to the invention is advantageous because the light is not radiated from outside the reactor over a distance into the interior of the reactor, whereby light components are lost through light scattering, reflection and absorption, but the light sources are in the reactor itself in the immediate vicinity of the microorganisms or plants are located and can irradiate the microorganisms or plants via flat structures, which means that there is hardly any loss of light and a high level of efficiency is achieved.
  • At least one plate-shaped outer wall surface, floor surface, ceiling surface or inner surface of the container and/or at least one tubular channel or a hollow profile, which is/are arranged in the container is at least partially made of a light-conducting glass or consists of plastic, with light being fed into this plate-shaped surface and/or in this tubular channel via at least one illuminant, which light is guided in the plate-shaped surface and/or in the tubular channel, the light being emitted via scattering means from the plate-shaped surface and/or is decoupled from the tubular channel or hollow profile.
  • parts of the container of the bioreactor such as wall surfaces, floor surfaces, etc. are used as plate-shaped light guides, into which light is radiated, for example from the front, via lamps, which is then guided in these surfaces and is coupled out via the surface.
  • the scattering means used for this purpose can be located in the plates, for example as light-scattering microparticles, or the surfaces are printed with light-scattering grids, for example.
  • the surfaces can also be engraved or milled, for example with light-scattering grids or structures.
  • structures built into the container can also be designed in the form of light-conducting surfaces or also channels.
  • tubular channels through which a medium flows in the container can be used as light guides and the light can thus be brought into the immediate vicinity of the microorganisms that are in the medium flowing in the container.
  • the heating of the structures serving as light guides is lower anyway, since the heat is distributed in the structure, compared to the immediate vicinity of a point light source.
  • At least one plate-shaped outer wall surface, floor surface, ceiling surface or inner surface of the container and/or at least one tubular channel, which is arranged in the container consists at least partially of an OLED panel or an OLED film or an OLED -Panel is attached to one of these plate-shaped surfaces.
  • Such OLED panels can be attached to any surface of the container and the microorganisms can be irradiated with light from close proximity, or if it is OLED foils and therefore flexible OLEDs, they can also be attached to cylindrical structures such as tubular channels and on these For example, channels through which the medium containing the microorganisms flows can be used directly as light sources and made self-luminous.
  • micro- or nanoparticles can be provided as the scattering agent, which are embedded in the plastic material or in the glass of the plate-shaped surface and/or the tubular channel and result in a uniform light emission over the entire outer and in the case of tubular channels, optionally also via the inner surface of the light guides, past which the medium containing the microorganisms flows.
  • plastics or also glass can be considered as materials for the light guides, with some types of glass being less suitable if they absorb light in certain wavelength ranges that are needed for the microorganisms to be exposed to them.
  • the person skilled in the art will therefore select a type of glass that is suitable for the respective application.
  • So-called acrylic glass is particularly suitable as the plastic material, ie polymethyl methacrylate or, for example, polycarbonate.
  • channels can be created in which the medium flowing through the channels is irradiated with light in the desired frequency or a defined frequency spectrum both from the inside and from the outside.
  • the lighting means light can be fed into the light-guiding structures that has a wavelength distribution similar to that of natural daylight or others Applications largely monochromatic light in a wavelength that is specifically tailored to the respective microorganisms or plants.
  • the container has planar built-in components that protrude inward from a wall surface at an angle and form flow obstacles for a medium flowing through the reactor and are surrounded by this medium, with these flat built-in components consisting of a light-conducting glass or plastic, comprise an OLED panel or an OLED film or an OLED panel or an OLED film is attached to them.
  • These inwardly protruding, flat installations represent flow obstacles for the flowing medium, through which the total distance covered by the medium when flowing through the container is lengthened, the flow is slowed down and the dwell time of the medium is increased. This also intensifies the irradiation of the microorganisms.
  • OLED panels or OLED foils has the advantage that, due to their structure, OLED lamps are already flat light sources with a uniform light output over the surface, so that light deflection or the use of scattering agents is always associated with a loss of light is not required.
  • the luminance and light intensity of OLEDs are generally lower than those of point light sources such as LEDs, which is not a disadvantage in the present application, but rather an advantage, since high luminance levels are usually not required for the irradiation of the microorganisms.
  • OLEDs there is no need to convert the light that is emitted primarily in a point form by the lighting means into planar light, as a result of which light losses are avoided.
  • the aforementioned flat built-in components which project inward at an angle, are often used in bioreactors of this type in order to slow down the flow of the medium through the container.
  • the invention therefore uses these internals for irradiating the microorganisms with light by making the internals self-luminous and light-emitting.
  • the internals can each start alternately from a first wall surface and a second wall surface opposite this first wall surface and each end at a distance in front of the wall surface opposite the wall surface from which they start, with the internals being essentially transverse to the main flow of the medium flowing through the container extend so that the medium flowing through the container is forced into a meandering flow along the internals.
  • the particular advantage of the solution according to the invention is that the light source is located in the reactor vessel itself, so that the light emitted by the self-luminous surfaces or tubular channels is used entirely for the irradiation of the microorganisms and no light is lost through emission into the environment of the reactor .
  • light-scattering or reflecting particles can also be located in the medium itself. In this way, the medium itself can become an additional and complementary element of the light guide.
  • a preferred alternative variant of the solution to the problem according to the invention provides that the bioreactor accommodates plants that are conveyed in the axial direction through self-luminous tubular, approximately horizontal channels or hollow profiles of the bioreactor, the tubular channels or hollow profiles being fed by a gaseous medium and/or by a liquid medium are flowed through, the liquid medium in particular washes around the root area of the plants.
  • a gaseous medium can be located above a liquid medium, for example a nutrient solution, so that the plants are in an artificial atmosphere in the area of their green shoots and absorb CO2 for photosynthesis, for example.
  • a specially tuned gas mixture can be used for the artificial atmosphere.
  • the plants can be irradiated with light via the walls of the self-luminous tubular channels.
  • the plants can be irradiated with light not only from above but also from below.
  • the tubular channels or hollow profiles can have any desired cross-section, ie, for example, a round cross-section or else an angular or polygonal cross-section or a cross-section of geometrically irregular shape.
  • this variant can be used for the cultivation of any plants, for example lettuce, vegetable plants or herbs.
  • the bioreactor according to the invention can have different geometric shapes and cross sections.
  • it can be a cuboid container with a rectangular cross section or a prismatic or cylindrical container with a polygonal, round, oval or elliptical cross section.
  • the bioreactor has tubular channels or cavities or only consists of such a channel or cavity, these channels or cavities through which a medium (nutrient medium) flows can also have any desired cross section exhibit and also a very variable geometric shape.
  • a channel or cavity forming a flow path may be arranged in a helicoidal or spiral configuration.
  • the flat internals mentioned above which emit light (they are luminous or can be illuminated themselves) and form flow obstacles for a medium flowing through the bioreactor, can consist of flat plates which, for example, protrude into the reactor at an angle, as described above, they However, they can also be designed as curved surfaces and have a wave shape, for example, especially when viewed in the direction of flow of the medium and/or the longitudinal direction of the reactor, so that in this variant too the medium flowing through the reactor meanders along the wave shape through the reactor.
  • FIG. 1 shows a schematically simplified vertical longitudinal section through the container of a bioreactor according to an exemplary embodiment of the present invention
  • FIG. 2 shows an enlarged detail section II from FIG. 1;
  • FIG. 3 shows a simplified longitudinal section through a tubular channel with self-illuminating walls according to an alternative exemplary variant of the present invention
  • FIG. 4 shows a schematic perspective view of an alternative reactor with corrugated internals
  • FIG. 5 shows an alternative embodiment variant in which the bioreactor has the external shape of a snail
  • FIG. 6 shows an alternative embodiment of a bioreactor which has the external shape of a spiral.
  • the container 10 has, for example, an approximately rectangular longitudinal section and has two parallel opposite vertical side walls 11, 12, an approximately horizontal bottom 13 connected to the two side walls 11, 12 in each case at the lower end and an approximately horizontal bottom 13 connected to the two side walls 11, 12 in each case at the upper end horizontal ceiling 14.
  • In the area of the floor 13 there is an inlet opening 15 for a liquid medium which flows into the container 10 and flows through the container from the bottom to the top.
  • the medium can leave the container 10 through an outlet opening 16 at the upper end in the cover 14 .
  • This liquid medium contains, for example, microalgae that produce a dye and for which the liquid medium serves as a nutrient. These microalgae are irradiated with light inside the container 10 according to the present invention.
  • the container 10 also has built-in components in the form of a plurality of horizontal plates 17, 18, 19 spaced apart from one another, each of which protrudes approximately horizontally from one of the two side walls 11, 12 into the interior of the container 10.
  • These horizontal plates 17, 18, 19 are arranged in the interior of the container 10 such that they are each firmly connected to one of the side walls 11, 12, protrude from this into the interior of the container and at a distance in front of the opposite side wall 11, 12 ends.
  • the arrangement of the adjacent side walls is preferably alternating, so that one plate 18 starts, for example, from the left side wall 11 and ends at a distance in front of the right side wall 12, while the next plate 19 arranged above it starts from the right side wall 12 and at a distance before the left side wall 11 ends.
  • flat OLED panels can also be used, for example, which are attached to the walls 11, 12 and fixtures 17, 18, 19 or on the floor 13 and ceiling 14 or are embedded in these elements and also emit light evenly over the surrender area. This ensures that the microorganisms in the medium are constantly and evenly irradiated with light from all sides as they slowly flow through the container.
  • tubular channels 30 extend in the bioreactor, which can extend vertically but also horizontally, depending on the application. With a vertical arrangement, the tubular channels 30 can be flowed through by a liquid medium, with a horizontal arrangement, the tubular channels can only partially be flowed through by a liquid medium, for example only in the lower third or in the lower half and a gaseous atmosphere can develop above this condition. Only a single tubular channel 30 is shown in the drawing in FIG.
  • these connectors are advantageously arranged so that the connectors 33 of the inner tube 31 are arranged offset to the connectors 34 of the outer tubes 32 viewed in the axial direction It is thus achieved that the shadows that result in the area of the connectors if they are not light-conducting are located in the inner tube 31 at a point where there is no connector 34 in the outer tube 32 and thus the Plants or microorganisms are then irradiated with light from the outside at a connector 33 on the inner tube 31 and correspondingly at a connector 34 on outer tube 32 from the inside. It can be seen in FIG.
  • the tubes 31, 32 are arranged vertically as in FIG partially block the cross section of the cavity 35 and thus force the flowing medium into a slow meandering flow.
  • the arrangement of the internals 36 can be such that they partially adjoin the wall of the outer tube 32 and are open towards the inner tube 31 and partially conversely adjoin the inner tube 31 and are open towards the outer tube 32, preferably at internals 36 that follow one another in the flow direction alternately.
  • FIG 4 shows an exemplary alternative embodiment of a bioreactor 10 according to the invention, in which this plate-shaped self-luminous fixtures 38 have a wave shape, so that the medium flowing through the bioreactor 10 is forced into a meandering flow with a correspondingly longer flow path, in which the microorganisms are in each case directly acted upon by the light which the built-in components 38 emit.
  • FIG. 5 shows a further exemplary alternative embodiment of a bioreactor 37 according to the invention, in which it has the external shape of a snail. Inside there are in turn plate-shaped fixtures 17, 18, which alternately protrude inwards from one or the other side wall of the reactor, so that the medium flows past these fixtures 17, 18 and has to cover a longer flow path.
  • FIG. 6 shows a further exemplary alternative embodiment in which the bioreactor 39 forms a tubular channel through which the medium flows and has the shape of a spiral, which also results in a longer flow path that the medium has to cover.

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Environmental Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La présente invention concerne un bioréacteur qui comprend un récipient (10) contenant des plantes, micro-organismes ou organismes phototrophes, au moins une source lumineuse étant associée audit bioréacteur, laquelle source lumineuse émet une lumière dans des fréquences appropriées pour les micro-organismes ou plantes. Selon l'invention, au moins des zones du récipient (10) lui-même ou d'éléments incorporés (17, 18, 19) à l'intérieur du récipient (10) sont autoluminescentes et, pour cela, soit ces zones sont constituées d'un matériau transparent ou translucide guidant la lumière, soit elles comprennent au moins une source de lumière ponctuelle ou en nappe intégrée dans la zone du récipient ou dans les éléments incorporés.
PCT/EP2022/077902 2021-10-07 2022-10-07 Bioréacteur WO2023057611A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102021126012.4A DE102021126012A1 (de) 2021-10-07 2021-10-07 Bioreaktor
DE102021126012.4 2021-10-07

Publications (1)

Publication Number Publication Date
WO2023057611A1 true WO2023057611A1 (fr) 2023-04-13

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PCT/EP2022/077902 WO2023057611A1 (fr) 2021-10-07 2022-10-07 Bioréacteur

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DE (1) DE102021126012A1 (fr)
WO (1) WO2023057611A1 (fr)

Citations (16)

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Publication number Priority date Publication date Assignee Title
DE19916597A1 (de) * 1999-04-13 2000-10-19 Fraunhofer Ges Forschung Photobioreaktor mit verbessertem Lichteintrag durch Oberflächenvergrößerung, Wellenlängenschieber oder Lichttransport
KR20030012650A (ko) * 2001-08-02 2003-02-12 한국과학기술연구원 광생물반응장치
WO2009090549A2 (fr) * 2008-01-18 2009-07-23 Algae Ltd Photobioréacteur
KR20100010060A (ko) * 2010-01-14 2010-01-29 인하대학교 산학협력단 원통형 광생물 반응기
EP2388310A1 (fr) * 2010-05-21 2011-11-23 Karlsruher Institut Für Technologie (KIT) Photobioréacteur
EP2520642A1 (fr) * 2011-05-03 2012-11-07 Bayer Intellectual Property GmbH Photobioréacteur avec une source lumineuse à mouvement rotatif oscillant
DE102012214493A1 (de) * 2012-08-14 2014-02-20 Air-Lng Gmbh Photobioreaktor zur Kultivierung von phototrophen Organismen
DE102013019889A1 (de) * 2013-11-28 2015-05-28 Airbus Defence and Space GmbH Photobioreaktor mit Matten aus licht-auskoppelnden Lichtleiterfasern und ein elektrisches Wanderfeld erzeugenden elektrisch leitfähigen Fasern
US20160046899A1 (en) * 2013-04-22 2016-02-18 Fermentalg Reactor with integrated illumination
DE102015222932A1 (de) * 2015-11-20 2017-05-24 Alga Pangea GmbH Anlage zur Aufzucht und Reproduktion von Mikroorganismen
DE202017107091U1 (de) * 2017-07-11 2017-11-30 Golden Algae Technology Ltd. Algenkultiviervorrichtung
DE102017214122A1 (de) * 2017-08-14 2019-02-14 Osram Gmbh Kammer für einen Photobioreaktor
DE102017008769A1 (de) * 2017-09-19 2019-03-21 Sartorius Stedim Biotech Gmbh Beleuchtung für einen Einweg-Photo-Bioreaktorr
EP3167042B1 (fr) 2015-09-30 2019-12-18 Subitec Gmbh Bioréacteur à alimentation en gaz interruptible
US20210017480A1 (en) * 2019-07-19 2021-01-21 Exxonmobil Research And Engineering Company Photobioreactor with annular chambers
CN112820952A (zh) * 2019-11-15 2021-05-18 通用汽车环球科技运作有限责任公司 电容器辅助的电池模块和系统

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US5162051A (en) 1989-11-22 1992-11-10 Martek Corporation Photobioreactor
CN2303849Y (zh) 1997-06-13 1999-01-13 徐明芳 光辐射塔板式光生物反应器
AU2008261616A1 (en) 2007-06-14 2008-12-18 Roger Stroud Apparatus and method for the culture of photosynthetic microorganisms

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19916597A1 (de) * 1999-04-13 2000-10-19 Fraunhofer Ges Forschung Photobioreaktor mit verbessertem Lichteintrag durch Oberflächenvergrößerung, Wellenlängenschieber oder Lichttransport
KR20030012650A (ko) * 2001-08-02 2003-02-12 한국과학기술연구원 광생물반응장치
WO2009090549A2 (fr) * 2008-01-18 2009-07-23 Algae Ltd Photobioréacteur
KR20100010060A (ko) * 2010-01-14 2010-01-29 인하대학교 산학협력단 원통형 광생물 반응기
EP2388310A1 (fr) * 2010-05-21 2011-11-23 Karlsruher Institut Für Technologie (KIT) Photobioréacteur
EP2520642A1 (fr) * 2011-05-03 2012-11-07 Bayer Intellectual Property GmbH Photobioréacteur avec une source lumineuse à mouvement rotatif oscillant
DE102012214493A1 (de) * 2012-08-14 2014-02-20 Air-Lng Gmbh Photobioreaktor zur Kultivierung von phototrophen Organismen
US20160046899A1 (en) * 2013-04-22 2016-02-18 Fermentalg Reactor with integrated illumination
DE102013019889A1 (de) * 2013-11-28 2015-05-28 Airbus Defence and Space GmbH Photobioreaktor mit Matten aus licht-auskoppelnden Lichtleiterfasern und ein elektrisches Wanderfeld erzeugenden elektrisch leitfähigen Fasern
EP3167042B1 (fr) 2015-09-30 2019-12-18 Subitec Gmbh Bioréacteur à alimentation en gaz interruptible
DE102015222932A1 (de) * 2015-11-20 2017-05-24 Alga Pangea GmbH Anlage zur Aufzucht und Reproduktion von Mikroorganismen
DE202017107091U1 (de) * 2017-07-11 2017-11-30 Golden Algae Technology Ltd. Algenkultiviervorrichtung
DE102017214122A1 (de) * 2017-08-14 2019-02-14 Osram Gmbh Kammer für einen Photobioreaktor
DE102017008769A1 (de) * 2017-09-19 2019-03-21 Sartorius Stedim Biotech Gmbh Beleuchtung für einen Einweg-Photo-Bioreaktorr
US20210017480A1 (en) * 2019-07-19 2021-01-21 Exxonmobil Research And Engineering Company Photobioreactor with annular chambers
CN112820952A (zh) * 2019-11-15 2021-05-18 通用汽车环球科技运作有限责任公司 电容器辅助的电池模块和系统

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