WO2023056029A1 - Agonistes bêta3-adrénergiques pour le traitement de troubles de la pousse des cheveux - Google Patents

Agonistes bêta3-adrénergiques pour le traitement de troubles de la pousse des cheveux Download PDF

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Publication number
WO2023056029A1
WO2023056029A1 PCT/US2022/045402 US2022045402W WO2023056029A1 WO 2023056029 A1 WO2023056029 A1 WO 2023056029A1 US 2022045402 W US2022045402 W US 2022045402W WO 2023056029 A1 WO2023056029 A1 WO 2023056029A1
Authority
WO
WIPO (PCT)
Prior art keywords
hair
adrenergic receptor
skin
receptor agonist
treatment
Prior art date
Application number
PCT/US2022/045402
Other languages
English (en)
Inventor
Evan J. FAHY
Original Assignee
The Board Of Trustees Of The Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Board Of Trustees Of The Leland Stanford Junior University filed Critical The Board Of Trustees Of The Leland Stanford Junior University
Publication of WO2023056029A1 publication Critical patent/WO2023056029A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Abstract

L'invention concerne des compositions topiques de soin de la peau et des cheveux pour améliorer la croissance et l'aspect de cheveux de mammifère chez un individu, lesdites compositions comprenant une dose d'un agoniste du récepteur adrénergique β3 efficace pour favoriser la pousse des cheveux.
PCT/US2022/045402 2021-10-01 2022-09-30 Agonistes bêta3-adrénergiques pour le traitement de troubles de la pousse des cheveux WO2023056029A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163251375P 2021-10-01 2021-10-01
US63/251,375 2021-10-01

Publications (1)

Publication Number Publication Date
WO2023056029A1 true WO2023056029A1 (fr) 2023-04-06

Family

ID=85783552

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2022/045402 WO2023056029A1 (fr) 2021-10-01 2022-09-30 Agonistes bêta3-adrénergiques pour le traitement de troubles de la pousse des cheveux

Country Status (1)

Country Link
WO (1) WO2023056029A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080249176A1 (en) * 2004-04-23 2008-10-09 Rasmussen Helge H Methods and Compositions for the Treatment of Myocardial Conditions
WO2010001391A1 (fr) * 2008-06-30 2010-01-07 Oron Zachar Application dermique de vasoconstricteurs
US20120197016A1 (en) * 2010-10-25 2012-08-02 The Procter & Gamble Company Screening methods of modulating adrenergic receptor gene expressions implicated in melanogenesis
US8748433B2 (en) * 2010-04-30 2014-06-10 Merck Sharp & Dohme Corp. β3 adrenergic receptor agonists

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080249176A1 (en) * 2004-04-23 2008-10-09 Rasmussen Helge H Methods and Compositions for the Treatment of Myocardial Conditions
WO2010001391A1 (fr) * 2008-06-30 2010-01-07 Oron Zachar Application dermique de vasoconstricteurs
US8748433B2 (en) * 2010-04-30 2014-06-10 Merck Sharp & Dohme Corp. β3 adrenergic receptor agonists
US20120197016A1 (en) * 2010-10-25 2012-08-02 The Procter & Gamble Company Screening methods of modulating adrenergic receptor gene expressions implicated in melanogenesis

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