WO2023045048A1 - Réfrigérateur pour stocker un échantillon biologique - Google Patents

Réfrigérateur pour stocker un échantillon biologique Download PDF

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Publication number
WO2023045048A1
WO2023045048A1 PCT/CN2021/129836 CN2021129836W WO2023045048A1 WO 2023045048 A1 WO2023045048 A1 WO 2023045048A1 CN 2021129836 W CN2021129836 W CN 2021129836W WO 2023045048 A1 WO2023045048 A1 WO 2023045048A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample
box
sample rack
horizontal direction
refrigerator
Prior art date
Application number
PCT/CN2021/129836
Other languages
English (en)
Chinese (zh)
Inventor
胡佳霖
邹富全
周荣
罗有志
江赈宇
Original Assignee
基点生物科技(成都)有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 基点生物科技(成都)有限公司 filed Critical 基点生物科技(成都)有限公司
Publication of WO2023045048A1 publication Critical patent/WO2023045048A1/fr

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D11/00Self-contained movable devices, e.g. domestic refrigerators
    • F25D11/02Self-contained movable devices, e.g. domestic refrigerators with cooling compartments at different temperatures
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D17/00Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces
    • F25D17/04Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces for circulating air, e.g. by convection
    • F25D17/042Air treating means within refrigerated spaces
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D17/00Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces
    • F25D17/04Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces for circulating air, e.g. by convection
    • F25D17/06Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces for circulating air, e.g. by convection by forced circulation
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D19/00Arrangement or mounting of refrigeration units with respect to devices or objects to be refrigerated, e.g. infrared detectors
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D21/00Defrosting; Preventing frosting; Removing condensed or defrost water
    • F25D21/06Removing frost
    • F25D21/08Removing frost by electric heating
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D23/00General constructional features
    • F25D23/02Doors; Covers
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D23/00General constructional features
    • F25D23/02Doors; Covers
    • F25D23/028Details
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D29/00Arrangement or mounting of control or safety devices
    • F25D29/005Mounting of control devices
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F25REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
    • F25DREFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
    • F25D2317/00Details or arrangements for circulating cooling fluids; Details or arrangements for circulating gas, e.g. air, within refrigerated spaces, not provided for in other groups of this subclass
    • F25D2317/04Treating air flowing to refrigeration compartments
    • F25D2317/041Treating air flowing to refrigeration compartments by purification
    • F25D2317/0411Treating air flowing to refrigeration compartments by purification by dehumidification
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02BCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
    • Y02B40/00Technologies aiming at improving the efficiency of home appliances, e.g. induction cooking or efficient technologies for refrigerators, freezers or dish washers

Definitions

  • the sample rack For the storage container at the lower part of the equipment, when accessing, lift the sample rack up to a certain height so that the sample rack is exposed to the storage container, and then use a robot to take and place the sample box, so that only the lower part of the device can be used to store samples, and the upper part is used to accommodate
  • the elevated sample rack causes waste of space and low space utilization.
  • two longitudinal beams are arranged in the top cavity, and the two longitudinal beams are arranged along the first horizontal direction and are respectively located on both sides of the sample rack assembly; The two ends are slidingly connected with two longitudinal beams respectively.
  • a thermal insulation cover plate is provided at the end of the box away from the fixed sample rack, and a rotary drive device is connected to one side of the thermal insulation cover plate to drive its rotation;
  • the rotary driving device is used to drive the insulation cover plate to rotate to close the gap between the sample rack and the box body which is the farthest away from the fixed sample rack; Top chamber and low temperature chamber.
  • Fig. 6 is a top view of the sample rack assembly in the refrigerator for storing biological samples shown in Fig. 1 .
  • the first driving unit 14, the second driving unit 15 and the third driving unit 16 are all placed in the top chamber 7, and the temperature of the top chamber 7 is higher than that of the low-temperature chamber 8, so it is unnecessary to use low-temperature driving components in the top chamber 7, which is extremely Great cost savings; secondly, the driving components are placed in the top cavity 7, which is more convenient for maintenance.
  • the sample box gripper 13 can be realized by existing technologies such as jaw cylinders.
  • the rack body 18 may include unit racks arranged in a row along the second horizontal direction, and the unit racks may be realized by a Chinese utility model patent with the publication number CN209757793U and the name is a sample cryopreservation rack.
  • the inside of the box body 2 is provided with a thermal insulation cover plate 26 at one end away from the fixed sample rack, and one side of the thermal insulation cover plate 26 is connected with a rotary drive device 27 that drives its rotation; the rotary drive device 27 is used to drive the thermal insulation
  • the cover plate 26 rotates to close the gap between the sample rack 9 farthest from the fixed sample rack and the box body 2; Top chamber 7 and low temperature chamber 8.
  • the refrigerator can also include a dehumidification structure 32;
  • the dehumidification structure 32 can include: a closed box 33, a window frame 34 embedded in the access opening 1, and a condenser 35 installed in the closed box 33;
  • the side wall of the port 1 is provided with an accommodating cavity for accommodating the closed box 33;
  • the closed box 33 is provided with an air inlet and an air outlet respectively;
  • a first fan 36 is installed at the air outlet; the air outlet of the first fan 36 faces the window frame 34 Setting;
  • the edge of the window frame 34 away from the end of the sample rack assembly 4 extends outward and forms a mounting flange 41, and handles 40 are connected to both sides of the mounting flange 41;
  • the inside of the window frame 34 is respectively provided with a first channel 38 and a second channel 39.

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Combustion & Propulsion (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Thermal Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Warehouses Or Storage Devices (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'invention concerne un réfrigérateur servant à stocker un échantillon biologique, comprenant : un corps de réfrigérateur (2) pourvu d'un orifice d'accès (1) sur une paroi latérale ; une porte d'étanchéité (3) destinée à fermer hermétiquement l'orifice d'accès (1) ; et un ensemble râtelier à échantillons (4), un élément de refroidissement (5) et un mécanisme de placement/retrait de boîte à échantillon (6) qui sont tous disposés à l'intérieur du corps de réfrigérateur (2). L'intérieur du corps de réfrigérateur (2) est divisé en une cavité supérieure (7) et une cavité à basse température (8) en haut et en bas. L'ensemble râtelier à échantillons (4) comprend une pluralité de râteliers à échantillons (9) disposés en une colonne le long d'une première direction horizontale. L'élément de refroidissement (5) et les râteliers à échantillons (9) sont toutes situés dans la cavité à basse température (8). L'un des deux râteliers à échantillons (9) situé au niveau de l'extrémité la plus à l'extérieur est un râtelier à échantillons fixe, et les râteliers à échantillons restants (9) sont tous des râteliers à échantillons mobiles. Le râtelier à échantillons fixe est fixé au corps de réfrigérateur (2), et les parties supérieures des râteliers à échantillons mobiles sont suspendues au corps de réfrigérateur (2) et reliées à un mécanisme d'entraînement (10) pour entraîner les râteliers à échantillons mobiles à coulisser selon un mouvement de va-et-vient le long de la première direction horizontale. Le mécanisme d'entraînement (10) est situé dans la cavité supérieure (7) et le mécanisme de placement/retrait de boîte à échantillon (6) est utilisé pour transférer une boîte à échantillon entre les râteliers à échantillons (9) et l'orifice d'accès (1). La partie supérieure du mécanisme de placement/retrait de boîte à échantillon (6) est suspendue à la cavité supérieure (7) et coulisse le long de la première direction horizontale.
PCT/CN2021/129836 2021-09-22 2021-11-10 Réfrigérateur pour stocker un échantillon biologique WO2023045048A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202111108166.1 2021-09-22
CN202111108166.1A CN113819699B (zh) 2021-09-22 2021-09-22 用于储存生物样本的冰箱

Publications (1)

Publication Number Publication Date
WO2023045048A1 true WO2023045048A1 (fr) 2023-03-30

Family

ID=78920824

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2021/129836 WO2023045048A1 (fr) 2021-09-22 2021-11-10 Réfrigérateur pour stocker un échantillon biologique

Country Status (2)

Country Link
CN (1) CN113819699B (fr)
WO (1) WO2023045048A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116735329A (zh) * 2023-06-09 2023-09-12 中国水产科学研究院黑龙江水产研究所 一种水环境dna分子样本快速前处理装置

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115843785A (zh) * 2022-12-29 2023-03-28 基点生物科技(成都)有限公司 一种生物样本低温存储设备
CN115843786B (zh) * 2023-03-01 2023-07-14 基点生物科技(成都)有限公司 生物样本低温存储设备

Citations (5)

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US5176202A (en) * 1991-03-18 1993-01-05 Cryo-Cell International, Inc. Method and apparatus for use in low-temperature storage
CN102269667A (zh) * 2011-06-21 2011-12-07 山东大学 一种生物医药样本冷藏存取自动控制系统
CN106976674A (zh) * 2017-04-11 2017-07-25 上海原能细胞医学技术有限公司 低温存储中转装置及其运行方法
CN107624751A (zh) * 2017-09-15 2018-01-26 上海原能细胞生物低温设备有限公司 低温存储系统
CN110641888A (zh) * 2019-09-19 2020-01-03 基点维科(成都)医疗机器人技术有限公司 一种生物样本库

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EP2896965A4 (fr) * 2012-09-12 2016-06-01 Hitachi High Tech Corp Dispositif de stockage d'objets de test, système de traitement d'objets de test, et procédé de commande de ceux-ci
CN207404320U (zh) * 2017-09-21 2018-05-25 基点维科(成都)医疗机器人技术有限公司 生物样本低温提取系统
CN211038338U (zh) * 2019-09-19 2020-07-17 基点维科(成都)医疗机器人技术有限公司 一种用于生物样本库存取窗口启闭的门结构
CN111637675B (zh) * 2020-06-01 2021-06-04 迪瑞医疗科技股份有限公司 一种样本低温自动储存设备及方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5176202A (en) * 1991-03-18 1993-01-05 Cryo-Cell International, Inc. Method and apparatus for use in low-temperature storage
CN102269667A (zh) * 2011-06-21 2011-12-07 山东大学 一种生物医药样本冷藏存取自动控制系统
CN106976674A (zh) * 2017-04-11 2017-07-25 上海原能细胞医学技术有限公司 低温存储中转装置及其运行方法
CN107624751A (zh) * 2017-09-15 2018-01-26 上海原能细胞生物低温设备有限公司 低温存储系统
CN110641888A (zh) * 2019-09-19 2020-01-03 基点维科(成都)医疗机器人技术有限公司 一种生物样本库

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116735329A (zh) * 2023-06-09 2023-09-12 中国水产科学研究院黑龙江水产研究所 一种水环境dna分子样本快速前处理装置
CN116735329B (zh) * 2023-06-09 2023-12-26 中国水产科学研究院黑龙江水产研究所 一种水环境dna分子样本快速前处理装置

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CN113819699B (zh) 2022-09-06
CN113819699A (zh) 2021-12-21

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