WO2023045048A1 - Réfrigérateur pour stocker un échantillon biologique - Google Patents
Réfrigérateur pour stocker un échantillon biologique Download PDFInfo
- Publication number
- WO2023045048A1 WO2023045048A1 PCT/CN2021/129836 CN2021129836W WO2023045048A1 WO 2023045048 A1 WO2023045048 A1 WO 2023045048A1 CN 2021129836 W CN2021129836 W CN 2021129836W WO 2023045048 A1 WO2023045048 A1 WO 2023045048A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sample
- box
- sample rack
- horizontal direction
- refrigerator
- Prior art date
Links
- 239000012472 biological sample Substances 0.000 title claims abstract description 36
- 239000000523 sample Substances 0.000 claims abstract description 193
- 230000007246 mechanism Effects 0.000 claims abstract description 50
- 238000001816 cooling Methods 0.000 claims abstract description 12
- 238000007789 sealing Methods 0.000 claims abstract description 4
- 238000009413 insulation Methods 0.000 claims description 25
- 229910052751 metal Inorganic materials 0.000 claims description 17
- 239000002184 metal Substances 0.000 claims description 17
- 238000004321 preservation Methods 0.000 claims description 12
- 238000007791 dehumidification Methods 0.000 claims description 8
- 230000005540 biological transmission Effects 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 238000010438 heat treatment Methods 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 239000000725 suspension Substances 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 229960005486 vaccine Drugs 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 229910000838 Al alloy Inorganic materials 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005138 cryopreservation Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D11/00—Self-contained movable devices, e.g. domestic refrigerators
- F25D11/02—Self-contained movable devices, e.g. domestic refrigerators with cooling compartments at different temperatures
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D17/00—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces
- F25D17/04—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces for circulating air, e.g. by convection
- F25D17/042—Air treating means within refrigerated spaces
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D17/00—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces
- F25D17/04—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces for circulating air, e.g. by convection
- F25D17/06—Arrangements for circulating cooling fluids; Arrangements for circulating gas, e.g. air, within refrigerated spaces for circulating air, e.g. by convection by forced circulation
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D19/00—Arrangement or mounting of refrigeration units with respect to devices or objects to be refrigerated, e.g. infrared detectors
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D21/00—Defrosting; Preventing frosting; Removing condensed or defrost water
- F25D21/06—Removing frost
- F25D21/08—Removing frost by electric heating
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D23/00—General constructional features
- F25D23/02—Doors; Covers
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D23/00—General constructional features
- F25D23/02—Doors; Covers
- F25D23/028—Details
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D29/00—Arrangement or mounting of control or safety devices
- F25D29/005—Mounting of control devices
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F25—REFRIGERATION OR COOLING; COMBINED HEATING AND REFRIGERATION SYSTEMS; HEAT PUMP SYSTEMS; MANUFACTURE OR STORAGE OF ICE; LIQUEFACTION SOLIDIFICATION OF GASES
- F25D—REFRIGERATORS; COLD ROOMS; ICE-BOXES; COOLING OR FREEZING APPARATUS NOT OTHERWISE PROVIDED FOR
- F25D2317/00—Details or arrangements for circulating cooling fluids; Details or arrangements for circulating gas, e.g. air, within refrigerated spaces, not provided for in other groups of this subclass
- F25D2317/04—Treating air flowing to refrigeration compartments
- F25D2317/041—Treating air flowing to refrigeration compartments by purification
- F25D2317/0411—Treating air flowing to refrigeration compartments by purification by dehumidification
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02B—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
- Y02B40/00—Technologies aiming at improving the efficiency of home appliances, e.g. induction cooking or efficient technologies for refrigerators, freezers or dish washers
Definitions
- the sample rack For the storage container at the lower part of the equipment, when accessing, lift the sample rack up to a certain height so that the sample rack is exposed to the storage container, and then use a robot to take and place the sample box, so that only the lower part of the device can be used to store samples, and the upper part is used to accommodate
- the elevated sample rack causes waste of space and low space utilization.
- two longitudinal beams are arranged in the top cavity, and the two longitudinal beams are arranged along the first horizontal direction and are respectively located on both sides of the sample rack assembly; The two ends are slidingly connected with two longitudinal beams respectively.
- a thermal insulation cover plate is provided at the end of the box away from the fixed sample rack, and a rotary drive device is connected to one side of the thermal insulation cover plate to drive its rotation;
- the rotary driving device is used to drive the insulation cover plate to rotate to close the gap between the sample rack and the box body which is the farthest away from the fixed sample rack; Top chamber and low temperature chamber.
- Fig. 6 is a top view of the sample rack assembly in the refrigerator for storing biological samples shown in Fig. 1 .
- the first driving unit 14, the second driving unit 15 and the third driving unit 16 are all placed in the top chamber 7, and the temperature of the top chamber 7 is higher than that of the low-temperature chamber 8, so it is unnecessary to use low-temperature driving components in the top chamber 7, which is extremely Great cost savings; secondly, the driving components are placed in the top cavity 7, which is more convenient for maintenance.
- the sample box gripper 13 can be realized by existing technologies such as jaw cylinders.
- the rack body 18 may include unit racks arranged in a row along the second horizontal direction, and the unit racks may be realized by a Chinese utility model patent with the publication number CN209757793U and the name is a sample cryopreservation rack.
- the inside of the box body 2 is provided with a thermal insulation cover plate 26 at one end away from the fixed sample rack, and one side of the thermal insulation cover plate 26 is connected with a rotary drive device 27 that drives its rotation; the rotary drive device 27 is used to drive the thermal insulation
- the cover plate 26 rotates to close the gap between the sample rack 9 farthest from the fixed sample rack and the box body 2; Top chamber 7 and low temperature chamber 8.
- the refrigerator can also include a dehumidification structure 32;
- the dehumidification structure 32 can include: a closed box 33, a window frame 34 embedded in the access opening 1, and a condenser 35 installed in the closed box 33;
- the side wall of the port 1 is provided with an accommodating cavity for accommodating the closed box 33;
- the closed box 33 is provided with an air inlet and an air outlet respectively;
- a first fan 36 is installed at the air outlet; the air outlet of the first fan 36 faces the window frame 34 Setting;
- the edge of the window frame 34 away from the end of the sample rack assembly 4 extends outward and forms a mounting flange 41, and handles 40 are connected to both sides of the mounting flange 41;
- the inside of the window frame 34 is respectively provided with a first channel 38 and a second channel 39.
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Combustion & Propulsion (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Thermal Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Warehouses Or Storage Devices (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
L'invention concerne un réfrigérateur servant à stocker un échantillon biologique, comprenant : un corps de réfrigérateur (2) pourvu d'un orifice d'accès (1) sur une paroi latérale ; une porte d'étanchéité (3) destinée à fermer hermétiquement l'orifice d'accès (1) ; et un ensemble râtelier à échantillons (4), un élément de refroidissement (5) et un mécanisme de placement/retrait de boîte à échantillon (6) qui sont tous disposés à l'intérieur du corps de réfrigérateur (2). L'intérieur du corps de réfrigérateur (2) est divisé en une cavité supérieure (7) et une cavité à basse température (8) en haut et en bas. L'ensemble râtelier à échantillons (4) comprend une pluralité de râteliers à échantillons (9) disposés en une colonne le long d'une première direction horizontale. L'élément de refroidissement (5) et les râteliers à échantillons (9) sont toutes situés dans la cavité à basse température (8). L'un des deux râteliers à échantillons (9) situé au niveau de l'extrémité la plus à l'extérieur est un râtelier à échantillons fixe, et les râteliers à échantillons restants (9) sont tous des râteliers à échantillons mobiles. Le râtelier à échantillons fixe est fixé au corps de réfrigérateur (2), et les parties supérieures des râteliers à échantillons mobiles sont suspendues au corps de réfrigérateur (2) et reliées à un mécanisme d'entraînement (10) pour entraîner les râteliers à échantillons mobiles à coulisser selon un mouvement de va-et-vient le long de la première direction horizontale. Le mécanisme d'entraînement (10) est situé dans la cavité supérieure (7) et le mécanisme de placement/retrait de boîte à échantillon (6) est utilisé pour transférer une boîte à échantillon entre les râteliers à échantillons (9) et l'orifice d'accès (1). La partie supérieure du mécanisme de placement/retrait de boîte à échantillon (6) est suspendue à la cavité supérieure (7) et coulisse le long de la première direction horizontale.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111108166.1 | 2021-09-22 | ||
CN202111108166.1A CN113819699B (zh) | 2021-09-22 | 2021-09-22 | 用于储存生物样本的冰箱 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2023045048A1 true WO2023045048A1 (fr) | 2023-03-30 |
Family
ID=78920824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2021/129836 WO2023045048A1 (fr) | 2021-09-22 | 2021-11-10 | Réfrigérateur pour stocker un échantillon biologique |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN113819699B (fr) |
WO (1) | WO2023045048A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116735329A (zh) * | 2023-06-09 | 2023-09-12 | 中国水产科学研究院黑龙江水产研究所 | 一种水环境dna分子样本快速前处理装置 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115843785A (zh) * | 2022-12-29 | 2023-03-28 | 基点生物科技(成都)有限公司 | 一种生物样本低温存储设备 |
CN115843786B (zh) * | 2023-03-01 | 2023-07-14 | 基点生物科技(成都)有限公司 | 生物样本低温存储设备 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5176202A (en) * | 1991-03-18 | 1993-01-05 | Cryo-Cell International, Inc. | Method and apparatus for use in low-temperature storage |
CN102269667A (zh) * | 2011-06-21 | 2011-12-07 | 山东大学 | 一种生物医药样本冷藏存取自动控制系统 |
CN106976674A (zh) * | 2017-04-11 | 2017-07-25 | 上海原能细胞医学技术有限公司 | 低温存储中转装置及其运行方法 |
CN107624751A (zh) * | 2017-09-15 | 2018-01-26 | 上海原能细胞生物低温设备有限公司 | 低温存储系统 |
CN110641888A (zh) * | 2019-09-19 | 2020-01-03 | 基点维科(成都)医疗机器人技术有限公司 | 一种生物样本库 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2896965A4 (fr) * | 2012-09-12 | 2016-06-01 | Hitachi High Tech Corp | Dispositif de stockage d'objets de test, système de traitement d'objets de test, et procédé de commande de ceux-ci |
CN207404320U (zh) * | 2017-09-21 | 2018-05-25 | 基点维科(成都)医疗机器人技术有限公司 | 生物样本低温提取系统 |
CN211038338U (zh) * | 2019-09-19 | 2020-07-17 | 基点维科(成都)医疗机器人技术有限公司 | 一种用于生物样本库存取窗口启闭的门结构 |
CN111637675B (zh) * | 2020-06-01 | 2021-06-04 | 迪瑞医疗科技股份有限公司 | 一种样本低温自动储存设备及方法 |
-
2021
- 2021-09-22 CN CN202111108166.1A patent/CN113819699B/zh active Active
- 2021-11-10 WO PCT/CN2021/129836 patent/WO2023045048A1/fr unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5176202A (en) * | 1991-03-18 | 1993-01-05 | Cryo-Cell International, Inc. | Method and apparatus for use in low-temperature storage |
CN102269667A (zh) * | 2011-06-21 | 2011-12-07 | 山东大学 | 一种生物医药样本冷藏存取自动控制系统 |
CN106976674A (zh) * | 2017-04-11 | 2017-07-25 | 上海原能细胞医学技术有限公司 | 低温存储中转装置及其运行方法 |
CN107624751A (zh) * | 2017-09-15 | 2018-01-26 | 上海原能细胞生物低温设备有限公司 | 低温存储系统 |
CN110641888A (zh) * | 2019-09-19 | 2020-01-03 | 基点维科(成都)医疗机器人技术有限公司 | 一种生物样本库 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116735329A (zh) * | 2023-06-09 | 2023-09-12 | 中国水产科学研究院黑龙江水产研究所 | 一种水环境dna分子样本快速前处理装置 |
CN116735329B (zh) * | 2023-06-09 | 2023-12-26 | 中国水产科学研究院黑龙江水产研究所 | 一种水环境dna分子样本快速前处理装置 |
Also Published As
Publication number | Publication date |
---|---|
CN113819699B (zh) | 2022-09-06 |
CN113819699A (zh) | 2021-12-21 |
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