WO2023024434A1

WO2023024434A1 - Disposable urine collection tube without need to be uncapped

Info

Publication number: WO2023024434A1
Application number: PCT/CN2022/074408
Authority: WO
Inventors: 武楠
Original assignee: 上海蜚誉生物科技有限公司
Priority date: 2021-08-23
Filing date: 2022-01-27
Publication date: 2023-03-02

Abstract

A disposable urine collection tube without need to be uncapped, comprising a tube cap (10), a diaphragm (40) and a tube body (30), wherein when the tube cap (10) is connected to the tube body (30), the diaphragm (40) is located between the tube body (30) and the tube cap (10), so that a closed space for holding urine to be tested is formed in the tube body (30); and the diaphragm (40) is a membrane-like structure that is liquid-tight and allows a sampling needle to penetrate therethrough, and has a hanging drop shape selected from the diaphragm (40) being concave toward the tube bottom or the diaphragm (40) being convex toward the tube opening. The top of the concave portion or the convex portion (401) can have a puncture surface (402), and the puncture surface (402) is flat, and is adapted to the sampling needle to allow same to penetrate therethrough. When the sampling tube is used to test the urine to be tested, the testing sampling needle directly penetrates the diaphragm (40) to sample the urine to be tested without opening the tube cap (10). In addition, the collection tube is adapted to different sampling needles to penetrate therethrough.

Description

Disposable urine collection tube without opening cap

technical field

The present application relates to the technical field of medical testing, in particular to a disposable urine collection tube.

Background technique

At present, medical institutions in my country have popularized automatic urine analyzers and urine sediment analyzers. The analyzers use aspiration needles to automatically collect urine for follow-up testing. Prior to this, inspectors had to manually unscrew the collection tube caps one by one. This sample pretreatment mode not only increased the low-end and repetitive work of technicians, but also increased the occupational exposure risk of medical staff.

Contents of the invention

After extensive research, the inventor of the present application has developed a disposable urine collection tube including a new type of diaphragm, which is easy to achieve the manufacturing process under the premise of ensuring the sealing performance.

In one aspect of the present application, a disposable urine collection tube that does not need to be opened is disclosed, including: a tube cover, a septum, and a tube body;

Wherein, when the tube cover is connected with the tube body, the diaphragm is located between the tube body and the tube cover, thereby forming a closed space inside the tube body for containing the urine to be tested;

Wherein, the septum is a membrane-like structure that is liquid-tight and allows the sampling needle to pass through, and has a pendant drop-like shape, and the pendant drop-like shape is selected from the following group: the septum is concave toward the bottom of the tube, or the septum is concave toward the bottom of the tube Nozzle convex;

The disposable urine collection tube without opening the cover is configured as follows: when sampling, the tube cover can be opened, the urine to be tested is loaded into the tube body and then the tube cover is covered, and the urine to be tested is collected. The liquid is sealed in the disposable urine collection tube; when the urine to be tested is detected, the detection sampling needle directly passes through the septum without opening the tube cover and passes through the urine to be tested. Take a urine sample.

In a preferred example, the depth h1 of the depression (referring to the distance h1 between the lowest point of the depression and the plane surrounding the diaphragm) is ≥ 2 mm, preferably ≥ 3 mm, more preferably 2-6 mm.

In a preferred example, the height h2 of the bulge (referring to the distance h2 between the highest point of the bulge and the plane around the diaphragm) is ≥ 2 mm, preferably ≥ 3 mm, more preferably 2-6 mm.

In a preferred example, the septum is fixedly disposed on, attached to, or adhered to the cap.

In a preferred example, the diaphragm has a thickness of t and a diameter of d, and the value range of t is 0.3≤t≤3mm; the value range of d is 8≤d≤25mm.

In a preferred example, the cap-free disposable urine collection tube has a capacity of 5-20ml.

In a preferred example, the tube cap and the tube body are detachably screwed together.

In a preferred example, one or more stop protrusions are provided on the outer side of the tube cover along the circumference, for preventing the disposable urine collection tube from rolling freely when placed horizontally.

In a preferred example, the membranous structure on the septum that allows the sampling needle to pass through is a non-penetrating notch.

In a preferred example, the non-penetrating notch has one or more characteristics selected from the following group:

(a) The ratio of the thickness of the non-penetrating notch to the thickness of the diaphragm ranges from 1% to 10%;

(b) The value range of the uncut thickness is 0.005-0.3mm.

In a preferred example, the non-penetrating notch is in the shape of a "ten" or a "Y".

In a preferred example, the diaphragm is made of soft plastic material.

In a preferred example, a plurality of reinforcing ribs are provided around the bottom of the nipple at the bottom of the tubular body.

In a preferred example, the disposable urine collection tube is adapted to an automatic urine analyzer or an automatic urine sediment analyzer, and the sampling needle is a sampling needle of an automatic urine analyzer or an automatic urine sediment analyzer the sampling needle.

Another aspect of the present application discloses a disposable urine collection tube that does not need to be opened, including: a tube cover, a diaphragm, and a tube body;

Wherein, the septum is a membrane-like structure that is liquid-tight and allows the sampling needle to pass through, and has a pendant drop-like shape, and the pendant drop-like shape is selected from the following group: the septum is concave toward the bottom of the tube, or the septum is concave toward the bottom of the tube The spout is convex, concave or the top of the convex portion has a piercing surface which is flat and fits and allows the sampling needle to pass through.

In a preferred example, the puncture surface is circular, and the circular diameter ds ranges from 0mm<ds≤10mm.

In a preferred example, the thickness of the concave portion or the convex portion decreases gradually along the direction extending from the outer edge to the puncture surface.

In a preferred example, the thickness of the concave part or the convex part is t1, and the thickness of the piercing surface of the septum is t2, wherein,

The value range of t1 is 0.5mm≤t1≤3mm; the value range of t2 is 5μm≤d≤1mm.

In a preferred example, the ratio of t1 to t2 is δ, wherein the value range of δ is 2≤δ≤10 ⁶ .

In a preferred example, the diaphragm further includes: a connection part, the thickness of the connection part is t3, wherein the range of t3 is 0.5mm≤t3≤3mm.

In a preferred example, threads are provided on the connecting portion, and the connecting portion is configured to realize the threaded connection with the pipe body.

In a preferred example, there is a non-penetrating notch on the membrane to assist the sampling needle to pass through, the non-penetrating notch is uniformly distributed along the circumference of the flat surface, and the non-penetrating notch is The traces extend from the outer edge of the septum to the outer edge of the flat puncture surface, and the number of non-penetrating notches is n, and the range of n is 0≤n≤6.

(b) The value range of the uncut thickness is 0.005-0.3mm.

In a preferred example, the value range of the height h3 from the piercing surface to the nozzle is: 2mm≤h3≤4mm.

In a preferred example, the diaphragm is made of soft plastic material.

The disposable urine collection tube according to the present application has at least the following technical effects:

1. It does not need to be manually removed, and it can be tested directly on the machine, which improves the automatic process of urine analysis, greatly reduces the workload of the inspectors, improves the working comfort, and improves the medical protection level of the inspectors;

2. Reduce the risk of contamination of urine samples;

3. The collection tube can remain still on the horizontal table, eliminating the inconvenience caused by random rolling or even falling of the collection tube;

4. The ratio of the thickness of the non-penetrating notch to the thickness of the diaphragm is 1%-10%. While the sampling needle is easy to penetrate, it ensures the sealing of the internal sample liquid and effectively avoids sample overflow.

5. The detachable diaphragm has various shapes and is suitable for different sampling needles to pass through.

6. The flat shape of the puncture surface is easy to realize in the manufacturing process.

Description of drawings

Fig. 1 is a schematic structural view of a disposable urine collection tube according to the present invention;

Fig. 2 is the front view of the disposable urine collection tube according to the utility model;

Fig. 3 is the front view of the tube body (not including the tube cover) of the disposable urine collection tube according to the present utility model;

Fig. 4a is the top view of the cap (connected with a concave diaphragm toward the bottom of the tube) of the disposable urine collection tube according to the present invention;

Fig. 4b is a bottom view of the cap (connected with a concave diaphragm towards the bottom of the tube) of the disposable urine collection tube according to the present utility model;

Fig. 4c is the bottom view of the tube cover (connected with the upward convex diaphragm towards the mouth of the tube) of the disposable urine collection tube according to the utility model;

Fig. 4 d is the top view of the cap (connected with the upward convex diaphragm towards the nozzle) of the disposable urine collection tube according to the present utility model;

Figure 5a is a top view of the diaphragm (including "Y" shaped notch) of the disposable urine collection tube according to the present invention;

Figure 5b is a top view of the diaphragm (including the "cross" shaped notch) of the disposable urine collection tube according to the present invention;

Fig. 6a is a top view structural diagram of the diaphragm (including "Y" shaped notch) of the disposable urine collection tube according to the present invention;

Fig. 6b is a top view structural diagram of the diaphragm (including the "cross" shaped notch) of the disposable urine collection tube according to the present utility model;

Fig. 7a is a schematic diagram of the structure of the diaphragm (including the "Y" shaped notch) of the disposable urine collection tube according to the utility model;

Fig. 7b is a schematic diagram of the structure of the diaphragm (including the "cross" shaped notch) of the disposable urine collection tube according to the utility model;

Fig. 8a is a schematic diagram of the thickness of the non-penetrating notch on the diaphragm of the disposable urine collection tube according to the present invention (concave in the shape of the hanging drop);

Fig. 8b is a schematic diagram of the thickness of the non-penetrating notch on the diaphragm of the disposable urine collection tube according to the present utility model (the shape of the hanging drop is convex);

Fig. 9 is a schematic diagram of a disposable urine collection tube according to the utility model (the tube cover is connected with a diaphragm protruding toward the mouth of the tube);

Fig. 10 is a schematic cross-sectional view of a disposable urine collection tube (the cap is connected with a diaphragm protruding upward towards the mouth of the tube) according to the utility model.

Fig. 11 is a front view of a disposable urine collection tube (with a convex or concave diaphragm connected to the cap) according to an embodiment of the present invention;

Fig. 12 is a side view of a disposable urine collection tube (with a convex or concave diaphragm connected to the cap) according to an embodiment of the present utility model;

Fig. 13 is a perspective view of a disposable urine collection tube (with a convex or concave diaphragm connected to the tube cover) according to an embodiment of the present utility model;

Fig. 14a is a top view of the cap (diaphragm with a concave portion) of a disposable urine collection tube according to another embodiment of the present utility model;

Figure 14b is a bottom view of the cap (diaphragm with a concave portion) of a disposable urine collection tube according to another embodiment of the present utility model;

Fig. 14c is a side view of the cap (diaphragm with a convex portion or a concave portion) of a disposable urine collection tube according to another embodiment of the present utility model;

Fig. 15a is a top view of a septum (with a raised portion and a piercing surface) of a disposable urine collection tube according to another embodiment of the present utility model;

Fig. 15b is a top view of a diaphragm (with a concave portion and a piercing surface) of a disposable urine collection tube according to another embodiment of the present invention;

Figure 15c is a side view of a septum (with a raised portion and a piercing surface) of a disposable urine collection tube according to another embodiment of the present invention;

Fig. 15d is a side view of a septum (with a concave portion and a piercing surface) of a disposable urine collection tube according to another embodiment of the present invention.

Explanation of reference signs:

10-tube cap

101-flange

102-stop protrusion

20 - first diaphragm

30-tube body

40 - second diaphragm

401-upper convex part

402-flat surface

403-connection part

Detailed ways

In the following description, many technical details are proposed in order to enable readers to better understand the application. However, those skilled in the art can understand that the technical solutions claimed in this application can be realized even without these technical details and various changes and modifications based on the following implementation modes.

the term

"Collection tube", "urine collection tube", "disposable urine collection tube" and "test tube" can be used interchangeably, and all refer to the disposable urine collection tube according to the present application.

A disposable urine collection tube as shown in FIGS. 1 to 2 includes a tube cover 10 , a first septum 20 and a tube body 30 . The cap 10 is cylindrical, with a height of 10mm, an outer diameter of the top of 19.5mm-21.4mm, and an inner diameter of 13.5mm-15mm. There is a through hole on the top, and the through hole runs through the cap; the outer side of the cap is the side away from the body. The circumferential direction of the through hole is provided with a flange 101 with a height of 2mm. The flange 101 can buffer and protect the diaphragm arranged inside the cap. One or more stop protrusions 102 are provided on the outside of the tube cover 10 along the circumferential direction to prevent the disposable urine collection tube from rolling freely when placed horizontally. The stop protrusion is in a semicircular shape with a diameter of 3-6mm. There are preferably 4 stop protrusions, which are evenly distributed along the circumference. The cap 10 can optionally be made of colored plastic.

The first septum 20 is fixedly disposed on, attached to, or adhered to the inner side of the tube cap 10 , that is, the side connected to the tube body, as shown in FIGS. 4 a to 4 b . Optionally, the septum is tightly sandwiched between the tube cover 10 and the tube body 30 when mated. The first membrane 20 has a shape of a pendant drop. The cap 10 to which the diaphragm is attached can be detachably connected to the body by a threaded connection, in this way, when connected to the body 30, the diaphragm is located between the cap and the body. The shape of the hanging drop is concave towards the bottom of the tube, or convex towards the mouth of the tube. As shown in Figures 5a to 7b, when the shape of the pendant drop is concave toward the bottom of the tube, the diameter is 20mm, and the value range of the depth _h ₁ of the concave is 2mm≤h1≤6mm, preferably _h1 is 4mm, and the concave The inner diameter of the shape is 13mm. As shown in Figures 9 to 10, when the pendant drop-like shape is convex toward the mouth _of the nozzle, the value range of the height _h2 of the convexity is 2mm≤h2≤6mm, preferably _h2 is 4mm, and the convexity can be Protrudes through the through hole in the top of the cap.

The thickness of the first diaphragm 20 is t, and the value range of t is 0.3≤t≤3mm; the diameter is d, and the value range of d is 8mm≤d≤25mm. Preferably 10-20mm. In another preferred example, the thickness t ₁ around the diaphragm ranges from 0.6-3 mm, preferably 0.8-1.5 mm; the thickness t ₂ at the center of the diaphragm ranges from 0.3-1 mm, preferably 0.4-0.6 mm.

As shown in FIG. 5a to FIG. 7b , there is a non-penetrating notch on the first diaphragm 20; the notch may be in the shape of a "Y" or a "cross"; the thickness of the non-penetrating notch is 20 μm. The cut-through rate is defined as the ratio of the thickness of the non-penetrating notch to the thickness of the diaphragm, and the cut-through rate ranges from 1% to 10%; the value range of the uncut thickness is 0.005-0.3mm. In this embodiment, the cut-through rate is 1%-10%. The length of a single notch from the center to the outside is 11 mm, and the intersection center of the notch is the center of the through hole of the cap 10 .

The diaphragm of the first diaphragm 20 is made of soft plastic material. In one embodiment, the first membrane is a hydrophobic silicone membrane.

As shown in FIG. 3 , the tube body 30 is made of transparent plastic material. There are volume measurement scales and sample upper and lower limit warning lines on the tube body. The height of the tube body is 105mm, the outer diameter is 16mm, and the inner diameter is 14mm. At the bottom of the tube, there is a fixed protrusion suitable for the automatic urine analyzer, that is, the bottom of the nipple, with a height of 12mm and a streamlined shape from top to bottom.

The capacity of the disposable urine collection tube without opening the cap is 5-20ml, preferably 8-15ml.

During use, the patient collects the urine sample in the tube body 30, and puts the tube cap 10 on the tube body to be screwed tightly. The non-penetrating notch diaphragm has airtightness, so that the sample liquid in the tube will not overflow when it is shaken. The collection tube is sent to the automatic urine analyzer, and the sampling needle pierces through the first septum 20 without hindrance and enters the inner cavity of the tube to absorb the sample. After sampling, the disposable urine collection tube can be used and discarded immediately.

Another embodiment of the present application is as follows.

A disposable urine collection tube as shown in FIGS. 11 to 12 includes a tube cover 10 , a second septum 40 and a tube body 30 . The cap 10 is cylindrical, with a height of 10 mm, an outer diameter of 19.5 mm-21.4 mm at the top, and an inner diameter of 13.5 mm-15 mm. A through hole is arranged on the top, and the through hole runs through the cap; A plurality of stop protrusions 102 are used to prevent the disposable urine collection tube from rolling freely when placed horizontally. The stop protrusion is in a semicircular shape with a diameter of 3-6mm. There are preferably 4 stop protrusions, which are evenly distributed along the circumference. The cap 10 can optionally be made of colored plastic.

The second diaphragm 40 is fixedly disposed on, attached to, or adhered to the inner side of the tube cap 10 , that is, the side connected to the tube body, as shown in FIGS. 11 to 13 . Optionally, the septum is tightly sandwiched between the tube cover 10 and the tube body 30 when mated. The second membrane 40 has a shape of a pendant drop. The shape of the hanging drop can have a convex part or a concave part. In one embodiment, the pendant drop shape has a raised portion, as shown in Figure 15a. At the top of the raised portion there is a flat surface, piercing surface 402, for fitting the autosampler and passing through the piercing needle. The second diaphragm 40 also has a connecting portion 403, which is a circumferential flange on the outer periphery of the diaphragm and has a screw thread, so that the second diaphragm 40 can be detachably connected to the pipe body with a threaded connection. In this way, when connected When on the tube body 30, the diaphragm is located between the tube cover and the tube body. In one embodiment, as shown in Fig. 15b, the shape of the pendant drop is concave toward the bottom of the tube, or convex toward the mouth of the tube. As shown in Figure 15b, when the shape of the pendant drop is concave toward the bottom of the tube, the diameter d _s of the piercing surface ranges from 2 mm≤d _s≤10mm . The value range of the height h ₃ from the puncture surface to the nozzle is: 2mm≤h ₃ ≤4mm.

The thickness of the second septum 40 is gradually changing, and the thickness decreases gradually along the direction extending from the concave portion or the convex portion along the outer edge to the puncture surface. As shown in Figure 15b, the thickness of the concave part is t ₁ , and the value range of t ₁ is 0.5mm≤t ₁ ≤3mm; the thickness of the flat puncture surface is t ₂ , and the value range of t ₂ is 5μm≤d≤1mm. In another preferred example, the thickness t ₂ of the piercing surface is 20-50 μm.

As shown in FIGS. 15 a to 15 d , there is a non-penetrating notch on the second diaphragm 40 ; the thickness of the non-penetrating notch is 20 μm. The ratio of the thickness of the non-penetrating notch to the thickness of the diaphragm is defined as the cut-through rate, and the cut-through rate ranges from 1% to 10%; the value range of the uncut thickness is 0.005-0.3mm. In this embodiment, the cut-through rate is 1%-10%.

The diaphragm of the second diaphragm 40 is made of soft plastic material. In one embodiment, the first membrane is a hydrophobic silicone membrane.

The tube body 30 is made of transparent plastic material. There are volume measurement scales and sample upper and lower limit warning lines on the tube body. The height of the tube body is 105mm, the outer diameter is 16mm, and the inner diameter is 14mm. At the bottom of the tube, there is a fixed protrusion suitable for the automatic urine analyzer, that is, the bottom of the nipple, with a height of 12mm and a streamlined shape from top to bottom.

When in use, the patient collects a urine sample in the tube body 30, and puts the tube cap 10 on the tube body to be screwed tightly. Since the puncture surface of the diaphragm is a flat surface, a high degree of sealing is ensured, and the probability of overflow of the liquid collected in the tube is close to 0%. The collection tube is sent to the automatic urine analyzer, and the sampling needle pierces through the second septum 40 without hindrance and enters the inner cavity of the tube to absorb the sample. After sampling, the disposable urine collection tube can be used and discarded immediately.

All documents mentioned in this application are considered to be included in the disclosure content of this application in their entirety so that they can be used as a basis for amendments when necessary. In addition, it should be understood that after reading the above disclosure content of the application, those skilled in the art may make various changes or modifications to the application, and these equivalent forms also fall within the scope of protection claimed in the application.

Claims

A disposable urine collection tube without opening the cover, characterized in that it includes: a tube cover, a diaphragm, and a tube body;

Wherein, when the tube cover is connected with the tube body, the diaphragm is located between the tube body and the tube cover, thereby forming a closed space inside the tube body for containing the urine to be tested;

Wherein, the septum is a membrane-like structure that is liquid-tight and allows the sampling needle to pass through, and has a pendant drop-like shape, and the pendant drop-like shape is selected from the following group: the septum is concave toward the bottom of the tube, or the septum is concave toward the bottom of the tube The nozzle is convex.
The disposable urine collection tube without opening the cap according to claim 1, characterized in that, the value range of the depth h 1 of the depression is 2 mm≤h 1 ≤6 mm.
The disposable urine collection tube without opening the cap according to claim 1, characterized in that, the value range of the height h 2 of the upward protrusion is 2 mm≤h 2 ≤6 mm.
The disposable urine collection tube without opening the cap according to claim 1, wherein the septum is fixed on, attached to, or adhered to the tube cap.
The disposable urine collection tube without opening the cover according to claim 1, wherein the thickness of the diaphragm is t, the diameter is d, and the value range of t is 0.3≤t≤3mm; the value range of d 8≤d≤25mm.
The disposable urine collection tube without opening cap according to claim 1, characterized in that the capacity of the disposable urine collection tube without opening cap is 5-20ml.
The disposable urine collection tube without opening the cap according to claim 1, characterized in that, the tube cap and the tube body are detachably threaded.
The disposable urine collection tube without opening the cover according to claim 1, wherein one or more stop protrusions are arranged on the outside of the tube cover along the circumferential direction to prevent the disposable urine from The free rolling of the collection tube when it is placed horizontally on the horizontal plane.
The disposable urine collection tube without opening the cap according to claim 1, characterized in that the membrane-like structure on the septum that allows the sampling needle to pass through is a non-penetrating notch.
The disposable urine collection tube without opening the cap according to claim 9, wherein the non-penetrating notch has one or more characteristics selected from the group below:

(a) The ratio of the thickness of the non-penetrating notch to the thickness of the diaphragm ranges from 1% to 10%;

(b) The value range of the uncut thickness is 0.005-0.3mm.
The disposable urine collection tube without opening the cap according to claim 5, wherein the non-penetrating notch is in the shape of a "cross" or a "Y".
The disposable urine collection tube without opening the cap according to claim 1, wherein the diaphragm is made of soft plastic material.
The disposable urine collection tube without opening the cap according to claim 1, wherein a plurality of reinforcing ribs are arranged around the bottom of the nipple at the bottom of the tube body.
The disposable urine collection tube without opening the cover according to claim 1, wherein the disposable urine collection tube is adapted to an automatic urine analyzer or an automatic urine sediment analyzer, and the sampling The needle is a sampling needle of an automatic urine analyzer or a sampling needle of an automatic urine sediment analyzer.
A disposable urine collection tube without opening the cover, characterized in that it includes: a tube cover, a diaphragm, and a tube body;

Wherein, when the tube cover is connected with the tube body, the diaphragm is located between the tube body and the tube cover, thereby forming a closed space inside the tube body for containing the urine to be tested;

Wherein, the septum is a membrane-like structure that is liquid-tight and allows the sampling needle to pass through, and has a pendant drop-like shape, and the pendant drop-like shape is selected from the following group: the septum is concave toward the bottom of the tube, or the septum is concave toward the bottom of the tube The spout is convex, concave or the top of the convex portion has a piercing surface which is flat and fits and allows the sampling needle to pass through.
The disposable urine collection tube without opening cap according to claim 15, characterized in that, the puncture surface is circular, and the diameter d s of the circle is in the range of 0mm< ds≤10mm .
The disposable urine collection tube without opening the cap according to claim 15, wherein the septum is fixedly arranged on, attached to, or adhered to the tube cap.
The disposable urine collection tube without opening the cap according to claim 15, characterized in that, the thickness of the concave part or the convex part is gradually reduced along the direction extending from the outer edge to the puncture surface.
The disposable urine collection tube without opening the cap according to claim 18, wherein the thickness of the concave part or the convex part is t1 , and the thickness of the puncture surface of the diaphragm is t2 ,in,

The value range of t 1 is 0.5mm≤t 1 ≤3mm; the value range of t 2 is 5μm≤d≤1mm.
The cap-free disposable urine collection tube according to claim 15, wherein the ratio of t 1 to t 2 is δ, wherein the range of δ is 2≤δ≤10 6 .
The disposable urine collection tube without opening the cover according to claim 20, wherein the diaphragm further comprises: a connecting part, the thickness of the connecting part is t3 , wherein the value range of t3 is 0.5 mm≤t 3 ≤3mm.
The disposable urine collection tube without opening cap according to claim 15, characterized in that the capacity of the disposable urine collection tube without opening cap is 5-20ml.
The disposable urine collection tube without opening the cap according to claim 22, wherein the tube cap and the tube body are detachably threaded.
The disposable urine collection tube without opening the cap according to claim 23, characterized in that, the connecting part is provided with threads, and the connecting part is configured to realize the threaded connection with the tube body.
The disposable urine collection tube without opening the cover according to claim 15, characterized in that, one or more stop protrusions are arranged on the outer side of the tube cover along the circumferential direction to prevent the disposable urine from The free rolling of the collection tube when it is placed horizontally on the horizontal plane.
The disposable urine collection tube without opening the cap according to claim 24, wherein the septum has a non-penetrating notch of a membranous structure that assists the sampling needle to pass through, and the non-penetrating notch is along the The circumference of the flat surface is evenly distributed, the non-penetrating notch extends from the outer edge of the septum to the outer edge of the flat puncture surface, the number of the non-penetrating notch is n, and the value range of n is 0≤ n≤6.
The disposable urine collection tube without opening the cap according to claim 26, wherein the non-penetrating notch has one or more characteristics selected from the following group:

(a) The ratio of the thickness of the non-penetrating notch to the thickness of the diaphragm ranges from 1% to 10%;

(b) The value range of the uncut thickness is 0.005-0.3mm.
The disposable urine collection tube without opening the cap according to claim 26, wherein the value range of the height h 3 from the puncture surface to the mouth of the tube is: 2mm≤h3≤4mm .
The disposable urine collection tube without opening the cap according to claim 15, wherein the diaphragm is made of soft plastic material.
The disposable urine collection tube without opening the cap according to claim 15, wherein a plurality of reinforcing ribs are arranged around the bottom of the nipple at the bottom of the tube body.
The disposable urine collection tube without opening the cover according to claim 15, wherein the disposable urine collection tube is adapted to an automatic urine analyzer or an automatic urine sediment analyzer, and the sampling The needle is a sampling needle of an automatic urine analyzer or a sampling needle of an automatic urine sediment analyzer.