WO2023023721A1 - Combined plant compounds for use in the treatment of viral infections including covid-19 - Google Patents
Combined plant compounds for use in the treatment of viral infections including covid-19 Download PDFInfo
- Publication number
- WO2023023721A1 WO2023023721A1 PCT/AU2022/050948 AU2022050948W WO2023023721A1 WO 2023023721 A1 WO2023023721 A1 WO 2023023721A1 AU 2022050948 W AU2022050948 W AU 2022050948W WO 2023023721 A1 WO2023023721 A1 WO 2023023721A1
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- WIPO (PCT)
- Prior art keywords
- approximately
- composition
- zingiber officinale
- glycine max
- siraitia grosvenorii
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Definitions
- the present invention relates to compound herbal composition and in particular to combined plant compounds for use in treatment of viral infections.
- CHM Chinese herbal medication
- the present invention seeks to provide a compound herbal composition which will overcome or substantially ameliorate at least some of the deficiencies of the prior art, or to at least provide an alternative.
- a compound herbal composition for treatment of or prevention of COVID-19 or other viral infections, and/or treatment of or prevention of one or more of medical conditions resulting from COVID-19 comprising: Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica, wherein the composition is prepared by compounding a therapeutically effective combination of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis,
- composition may further comprise Tetradium ruticarpum.
- composition may further comprise Alpinia oxyphylla.
- composition may further comprise Cullen corylifolium.
- composition may further comprise Cornus officinalis.
- composition may further comprise Scutellaria baicalensis.
- composition of may further comprise Forsythia suspensa.
- composition of may further comprise Dolichos lablab.
- composition may further comprise Coix lachryma-jobi.
- composition may further comprise an effective amount of each of Agastache rugosa.
- composition may further comprise Myristica fragrans.
- composition may further comprise Cinnamomum cassia.
- composition may further comprise Zingiber officinale.
- composition may further comprise Foeniculum vulgare.
- composition may further comprise Zanthoxylum bungeanum.
- composition may further comprise Astragalus membranaceus.
- composition may further comprise Chrysanthemum indicum.
- composition may further comprise Taraxacum mongolicum.
- composition may further comprise Viola yedoensis.
- composition may further comprise Begonia fimbristipula.
- composition may further comprise Scutellaria baicalensis.
- composition may further comprise Forsythia suspensa.
- composition may further comprise Scaphium scaphigerum.
- composition may further comprise Houttuynia cordata.
- composition may further comprise Gardenia jasminoides.
- composition may further comprise Nelumbo nucifera.
- composition may further comprise Lophatherum gracile.
- composition may further comprise Houttuynia cordata.
- composition may further comprise Dioscorea oppositifolia.
- composition may further comprise Amomum villosum.
- composition may further comprise Cornus officinalis.
- composition may further comprise Euryale ferox.
- An effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica in the therapeutically effective combination may comprise between 6.5 wt% to 10wt% of Angelica dahurica, between 3 to 4.5 wt% of Elsholtzia splendens, between 5.5 wt% to 8 wt% of Lonicera japonica, between 8.5 wt% to 12.5wt% of Glycine max, between 7 wt% to 10.5wt% of Siraitia grosvenorii, between 7 wt% to 10.5 wt% of Zingiber officinale, between 8.5 wt% to 12.5% of Platy
- the composition may comprise an additive.
- the additive may be maltodextrin.
- the compound herbal composition may be provided in any one of the following dosage forms: powdered form or tablet or capsule or paste or liquid form for oral consumption, or inhalants or injectable liquid.
- the liquid form for oral consumption may be a concentrated or a diluted drink.
- a method of treating COVID-19 or other viral infections, and/or one or more medical conditions resulting from CO VID-19 in a subject in need thereof comprising administering a therapeutically effective amount of the compound herbal composition.
- the one or more medical conditions may comprise pneumonia and/or acute respiratory syndrome and/or persistent pulmonary damage and/or post-viral fatigue and/or chronic cardiac complications.
- a method of preventing occurrence and/or reducing severity of one or more medical conditions resulting from COVID-19 and/or improving human body immunity in a subject in need thereof comprises administering a therapeutically effective amount of the compound herbal composition.
- the one or more medical conditions may comprise pneumonia and/or acute respiratory syndrome and/or persistent pulmonary damage and/or post-viral fatigue and/or chronic cardiac complications.
- An effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica in the therapeutically effective combination for a medicinal version for a cold body constitution may comprise approximately 9 wt% of Angelica dahurica, approximately 4 wt% of Elsholtzia splendens, approximately 7.8 wt% of Lonicera japonica, approximately 12.5wt% of Glycine max, approximately 10 wt% Siraitia grosvenorii, approximately 10 wt% of Zingiber officinale
- the composition may further comprise Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, and Forsythia suspensa, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, and Forsythia suspensa in the therapeutically effective combination for a medicinal version for a subject having a cold body constitution and may comprise approximately 6.5
- the composition may further comprise Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Dolichos lablab, and Coix lachryma-jobi, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Dolichos lablab, and Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a cold body constitution that
- the composition may further comprise Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale(Dry), Alpinia oxyphylla in the therapeutically effective combination for a dietary version for a subject having a cold body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0
- the composition may further comprise Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Foeniculum vulgare, Zanthoxylum bungeanum, Zingiber officinale(Dry), Astragalus membranaceus, Agastache rugosa, Dolichos lablab, and Coix lachryma-jobi in the therapeutically effective combination for dampness resolving dietary version for a subject having a
- the composition may further comprise Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa in the therapeutically effective combination for a medicinal version for a subject having a hot body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt%
- composition of claim 1 may further comprise Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a hot body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium
- the composition may further comprise Scaphium scaphigerum, Chrysanthemum indicum, Taraxacum mongolicum, Houttuynia cordata, Gardenia jasminoides in the therapeutically effective combination for a dietary version for a subject having a hot body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrr
- the composition may further comprise Gardenia jasminoides, Nelumbo nucifera, Lophatherum gracile, Houttuynia cordata , Agastache rugosa, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving dietary version for a subject having a hot body constitution and may comprise approximately 6.8 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, approximately 9.1 wt% of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt
- the composition may further comprise Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, and Cornus officinalis in the therapeutically effective combination for a medicinal version for a subject having a weak body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 w
- the composition may further comprise Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a weak body constitution and may comprise approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites
- the composition may further comprise Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a weak body constitution that may comprise approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites
- the composition may further comprise Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis in the therapeutically effective combination for a dietary version for a subject having a weak body constitution and comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt
- the composition may further comprise Dioscorea oppositifolia, Euryale ferox, Amomum villosum, Astragalus membranaceus, Agastache rugosa, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving dietary version for a subject having a weak body constitution and may comprise approximately 6.9 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 5.9 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, 9.1 wt% of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt%
- the present invention relates to a compound herbal composition for treatment of COVID- 19, symptoms of COVID-19 and/or other respiratory conditions.
- the present invention also relates to compound herbal composition for prevention and treatment of pneumonia, lung complications, acute respiratory syndrome, persistent pulmonary damage, post-viral fatigue, and chronic cardiac complications resulted from virus infections such as COVID19.
- the present invention also relates to a compound herbal composition for the prevention and treatment of symptoms caused by viral infections including fever, headache, cough, chills, muscle aches and pains, fatigue, stomach conditions and difficulty in breathing.
- the present invention comprises a foundation formulation comprising:
- Angelica dahurica Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandiflorus, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica.
- the invention provides formulations suitable for three types of body constitutions and is optimised for Australian geographic and demographic conditions.
- the 12 different variations are categorized according to four body types.
- the compound herbal compositions are specially designed forthree different types of unhealthy body constitutions i.e. Heat, Cold, and Weak.
- an “unhealthy” body constitution such as “Heat”, “Dampness-heat”, “Cold”, “Cold-dampness”, “Weak”, “Weak-dampness”, and “Heat- or Cold- dryness” is characterised by subnormal body temperature and other clinical manifestations.
- the Dampness resolving variants can sorted into the Qu Shi Pai Du decoction range, and the others under Qing Fei Pai Du decoction range.
- Variants for the four body types comprise: medicinal version, dampness resolving medicinal version, dietary version and dampness resolving dietary version.
- the foundation formulation comprises: Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonica 1 ,3g, Glycine max2.0, Siraitia grosvenorii 1 ,7g, Zingiber officinale 1 ,7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1 .7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g.
- the medicinal version of the compound herbal composition comprises Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, and Forsythia suspensa in addition to the foundation formulation.
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1 ,7g, Zingiber officinale 1 ,7g, Platycodon grandifloras 2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Tetradium ruticarpum 1 ,35g, Alpinia oxyphylla 1.1g, Cullen corylifolium 1.23g, Cornus officinalis 1.2g, Scutellaria baicalensis 0.82g, Forsythia suspensa 0.8g, maltodextrin.
- the dampness resolving medicinal version of the compound herbal composition comprises Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Dolichos lablab, and Coix lachryma-jobi in addition to the foundation formulation.
- the dietary version of the compound herbal composition comprises Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla.
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1 .7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Agastache rugosa 0.25g, Myristica fragrans 1.68g, Cinnamomum cassia 0.34g, Zingiber officinale(Dry) 2.55g, Alpinia oxyphylla 1 ,68g, maltodextrin
- the dampness resolving dietary version of the compound herbal composition comprises Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla in addition to the foundation formulation.
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1 .7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Foeniculum vulgare 1.0g, Zanthoxylum bungeanum 1.0g, Zingiber officinale(Dry) 1.0g, Astragalus membranaceus 1.5g, Agastache rugosa0.3g, Dolichos lablab 0.6g, Coix lachryma-jobi 1 .1g, maltodextrin [94] Heat Body Constitution
- a medicinal version of a compound herbal composition for a subject having a hot body constitution comprises Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa in addition to the foundation formulation.
- a therapeutically effective combination for a medicinal version of a compound herbal composition for a subject having a hot body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.3 wt % of Chrysanthemum indicum, approximately 4.7 wt%
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0g, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1 ,7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Chrysanthemum indicum 1 .45g, Taraxacum mongolicum 1.08g, Viola yedoensis 0.96g, Begonia fimbristipula 1.0g, Scutellaria baicalensis 1.0g, Forsythia suspensa 1 .0g, maltodextrin.
- a Dampness resolving medicinal version for a subject having a hot body constitution comprises: Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa.
- a therapeutically effective combination for a dampness resolving medicinal version for a subject having a hot body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.3 wt % of Chrysanthemum indicum, approximately 4.7 wt%
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Chrysanthemum indicum 1.45g, Taraxacum mongolicum 1.08g, Viola yedoensis 0.96g, Begonia fimbristipula 1.0g, Dolichos lablab 0.6g, Coix lachryma-jobi 1 ,41g, maltodextrin.
- a dietary version for a subject having a hot body constitution comprises Scaphium scaphigerum, Chrysanthemum indicum, Taraxacum mongolicum, Houttuynia cordata, Gardenia jasminoides in addition in addition to the foundation formulation.
- a therapeutically effective combination for a dietary version for a subject having a hot body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.5 wt% of Scaphium scaphigerum, approximately 6.5 wt % of Chrysanthemum
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1 .7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Scaphium scaphigerum 1 ,5g, Chrysanthemum indicum 1.5g, Taraxacum mongolicum 1 .35g, Houttuynia cordata 1 .05g, Gardenia jasminoides 1.1 g, maltodextrin.
- a Dampness resolving dietary version comprises Gardenia jasminoides, Nelumbo nucifera, Lophatherum gracile, Houttuynia cordata , Agastache rugosa, Dolichos lablab, Coix lachryma-job in addition to the foundation formulation.
- a therapeutically effective combination for a dampness resolving dietary version of a compound herbal composition for a subject having a hot body constitution comprises approximately 6.8 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, approximately 9.1 wt% of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt% of Allium cepa, approximately 7.8 wt% of Glycyrrhiza uralensis, approximately 3.2 wt% of Prunus persica, approximately 9.1 wt% of Gardenia jasminoides, approximately 2.7
- a medicinal version of a compound herbal composition for a subject having a weak body constitution comprises Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, and Cornus officinalis in addition to the foundation formulation.
- a therapeutically effective combination for a medicinal version of a compound herbal composition for a subject having a weak body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 4.3 wt% of Dioscorea oppositifolia, approximately 13.0 wt% of Astrag
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0g, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Dioscorea oppositifolia 1.0g, Astragalus membranaceus 3.0g, Cinnamomum cassia 0.25g, Zingiber officinale(Dry) 0.5g, Amomum villosum 0.5g, Cornus officinalis 1.25g, maltodextrin
- a dampness resolving medicinal version of a compound herbal composition for a subject having a weak body constitution comprises Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in addition to the foundation formulation.
- a therapeutically effective combination of a compound herbal composition for a dampness resolving medicinal version for a subject having a weak body constitution comprises approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.3 wt% of Allium cepa, approximately 7.9 wt% of Glycyrrhiza uralensis, approximately 3.3 wt% of Prunus persica, approximately 4.7 wt% of Dioscorea oppositifolia, approximately 9.3
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0g, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1 .7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Dioscorea oppositifolia 1.0g, Astragalus membranaceus 2.0g, Cinnamomum cassia 0.25g, Zingiber officinale(Dry) 0.25g, Amomum villosum 0.25g, Cornus officinalis 1.25g, Dolichos lablab 0.5g, Coix lachryma-jobi 1.0g, maltodextrin
- a dietary version of a compound herbal composition for a subject having a weak body constitution comprises Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in addition to the foundation formulation.
- a therapeutically effective combination for a dietary version of a compound herbal composition for a subject having a weak body constitution comprises approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.3 wt% of Allium cepa, approximately 7.9 wt% of Glycyrrhiza uralensis, approximately 3.3 wt% of Prunus persica, approximately 4.7 wt% of Dioscorea oppositifolia, approximately 9.3 wt% of As
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0g, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1 .7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Dioscorea oppositifolia 1.25g, Astragalus membranaceus 3.0g, Cinnamomum cassia 0.25g, Zingiber officinale (Dry) 0.5g, Amomum villosum 0.5g, Cornus officinalis 1.0g, maltodextrin.
- a dampness resolving dietary version for a subject having a weak body constitution further comprises Dioscorea oppositifolia, Euryale ferox, Amomum villosum, Astragalus membranaceus, Agastache rugosa, Dolichos lablab, Coix lachryma-jobi.
- a therapeutically effective combination for a dampness resolving dietary version of a compound herbal composition for a subject having a weak body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 5.4 wt% of Dioscorea oppositifolia, approximately 13
- Angelica dahurica 1.5g Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Dioscorea oppositifolia 1.0g,Euryale ferox 1.0g, Amomum villosum 0.5g, Astragalus membranaceus 2.0g, Agastache rugosa 0.3g, Dolichos lablab 0.6g, Coix lachryma-jobi 1.1g, maltodextrin.
- the example compositions can include suitable additives.
- the 12 examples provided above include maltodextrin as an additive but it is envisaged that in other embodiments, other additives can be used.
- the compound herbal composition can be provided in any one of the following dosage forms: powdered form or tablet or capsule or paste or liquid form for oral consumption, or inhalants or injectable liquid.
- the liquid form for oral consumption can be a concentrated or a diluted drink including water or other suitable dilutant.
- Example of using the composition for treatment of a patient with a Heat body constitution with dampness [136] Symptoms of patient: Cough, yellow phlegm, sore throat, headache, mild fever, muscle pain, dry mouth, constipation and tiredness and sleepy for two days. Red tongue, Thick and greasy tongue coating, Floating and rapid and slippery pulse.
- Example Composition 1 Dosage regimen: The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
- Symptoms of patient Cough, white phlegm, sore throat, dripping nose, headache, muscle pain, limbs cold, diarrhea, and tiredness sleepy for two days.
- Dosage regimen The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
- Dosage regimen The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
- Symptoms of patient Cough, sore throat, headache, mild fever, muscle pain, dry mouth, constipation anxiety and tiredness for two days. Red tongue, Floating and rapid and pulse.
- Dosage regimen The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
- Dosage regimen The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
- Dosage regimen The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
- Herbal formulations are provided which reduce the occurrence of viral infections and can prevent and treat complications associated with COVID-19.
- the invention provides compositions for use in treating COVID-19 or other viral infections, and/or one or more medical conditions resulting from COVID-19 in a subject in need thereof.
- the one or more medical conditions can comprise pneumonia and/or acute respiratory syndrome and/or persistent pulmonary damage and/or post-viral fatigue and/or chronic cardiac complications.
- the compound herbal compositions can prevent occurrence and/or reduce severity of one or more medical conditions resulting from COVID-19 and/or improve human body immunity.
- compositions have been found to be effective in treating a range of symptoms including cough, fever, fatigue, difficulty in breathing, dry throat, bitterness in the mouth, and symptoms of mental exhaustion.
Abstract
The present invention is directed to a compound herbal composition for treatment of or prevention of COVID-19 or other viral infections, and/or treatment of or prevention of one or more of medical conditions resulting from COVID-19, comprising: Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica. Further herbal extracts can also be added to this base composition, including Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, Forsythia suspensa, Dolichos lablab, Coix lachryma-jobi, Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale, Foeniculum vulgare, Zanthoxylum bungeanum, Astragalus membranaceus, Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scaphium scaphigerum, Houttuynia cordata, Gardenia jasminoides, Nelumbo nucifera, Lophatherum gracile, Dioscorea oppositifolia, Amomum villosum, Cornus officinalis and Euryale ferox.
Description
COMBINED PLANT COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS INCLUDING COVID-19
Field of the Invention
[1] The present invention relates to compound herbal composition and in particular to combined plant compounds for use in treatment of viral infections.
[2] The invention has been developed primarily for use in treating COVID-19 and related complications and will be described hereinafter with reference to this application. However, it will be appreciated that the invention is not limited to this particular field of use.
Background of the Invention
[3] The COVID-19 pandemic in the world has infected millions of people and caused many deaths.
[4] At an early stage of the COVIC19 pandemic, China’s hospital system was overwhelmed with COVID patients and death rate was very high.
[5] Chinese herbal medication (CHM) which comprises combined plant compounds has been used to treat symptoms of COVID-19. In a recent study, Fan et al in a review article titled “Chinese herbal medicine for COVID-19: Current evidence with systematic review and meta-analysis”, reported on various controlled trials in China where CHM has been used to treat COVID-19. It was found that treatment including CHM reduced symptoms in a number of patients with COVID-19.
[6] On 20 August 2021 , there have been 209,876,613 confirmed global cases of Covid- 19, 122,586 cases in China. There have been 4,400,284 deaths. 5674 cased in China, reported to WHO. Six months after reaching 100 million cases effected by new variants it has been reported that there are 21 ,446 cases in China. The rate of mortality and growth in number of cases in China is significantly lower than the global rate. Treatment by CHM has likely played an important role, because CHM is not only used in the treatment of confirmed patients, but is also widely used in the prevention of COVID-19 for public in China.
[7] Due to differences in geographic and environmental conditions, dietary traditions, and demographic variations, the CHM medications vary in efficaciousness.
[8] The present invention seeks to provide a compound herbal composition which will overcome or substantially ameliorate at least some of the deficiencies of the prior art, or to at least provide an alternative.
[9] It is to be understood that, if any prior art information is referred to herein, such reference does not constitute an admission that the information forms part of the common general knowledge in the art, in Australia or any other country.
Summary of the Invention
[10] In accordance with an aspect of the present disclosure, there is provided a compound herbal composition for treatment of or prevention of COVID-19 or other viral infections, and/or treatment of or prevention of one or more of medical conditions resulting from COVID-19, comprising: Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica, wherein the composition is prepared by compounding a therapeutically effective combination of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica.
[11] Use of the compound herbal composition in a therapeutically effective amount in the manufacture of a medicament for administration to a patient in the therapeutic treatment of and/or prevention of COVID-19 or other viral infections and/or treatment of and/or prevention of one or more of medical conditions resulting from COVID-19, is provided.
[12] The composition may further comprise Tetradium ruticarpum.
[13] The composition may further comprise Alpinia oxyphylla.
[14] The composition may further comprise Cullen corylifolium.
[15] The composition may further comprise Cornus officinalis.
[16] The composition may further comprise Scutellaria baicalensis.
[17] The composition of may further comprise Forsythia suspensa.
[18] The composition of may further comprise Dolichos lablab.
[19] The composition may further comprise Coix lachryma-jobi.
[20] The composition may further comprise an effective amount of each of Agastache rugosa.
[21] The composition may further comprise Myristica fragrans.
[22] The composition may further comprise Cinnamomum cassia.
[23] The composition may further comprise Zingiber officinale.
[24] The composition may further comprise Foeniculum vulgare.
[25] The composition may further comprise Zanthoxylum bungeanum.
[26] The composition may further comprise Astragalus membranaceus.
[27] The composition may further comprise Chrysanthemum indicum.
[28] The composition may further comprise Taraxacum mongolicum.
[29] The composition may further comprise Viola yedoensis.
[30] The composition may further comprise Begonia fimbristipula.
[31] The composition may further comprise Scutellaria baicalensis.
[32] The composition may further comprise Forsythia suspensa.
[33] The composition may further comprise Scaphium scaphigerum.
[34] The composition may further comprise Houttuynia cordata.
[35] The composition may further comprise Gardenia jasminoides.
[36] The composition may further comprise Nelumbo nucifera.
[37] The composition may further comprise Lophatherum gracile.
[38] The composition may further comprise Houttuynia cordata.
[39] The composition may further comprise Dioscorea oppositifolia.
[40] The composition may further comprise Amomum villosum.
[41] The composition may further comprise Cornus officinalis.
[42] The composition may further comprise Euryale ferox.
[43] An effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica in the therapeutically effective combination may comprise between 6.5 wt% to 10wt% of Angelica dahurica, between 3 to 4.5 wt% of Elsholtzia splendens, between 5.5 wt% to 8 wt% of Lonicera japonica, between 8.5 wt% to 12.5wt% of Glycine max, between 7 wt% to 10.5wt% of Siraitia grosvenorii, between 7 wt% to 10.5 wt% of Zingiber officinale, between 8.5 wt% to 12.5% of Platycodon grandifloras, between 7.5 wt% to 10.5 wt % of Imperata cylindrica, between 3.0 wt% to 5.0 wt% of Phragmites australis, between 3.0 wt% to 4.5 wt% of Allium cepa, between 7 wt% to 10.5 wt% of Glycyrrhiza uralensis and between 3 wt% to 4.5 wt% of Prunus persica.
[44] The composition may comprise an additive. The additive may be maltodextrin.
[45] The compound herbal composition may be provided in any one of the following dosage forms: powdered form or tablet or capsule or paste or liquid form for oral consumption, or inhalants or injectable liquid. The liquid form for oral consumption may be a concentrated or a diluted drink.
[46] In another aspect, there is provided a method of treating COVID-19 or other viral infections, and/or one or more medical conditions resulting from CO VID-19 in a subject in need thereof, comprising administering a therapeutically effective amount of the compound herbal composition.
[47] The one or more medical conditions may comprise pneumonia and/or acute respiratory syndrome and/or persistent pulmonary damage and/or post-viral fatigue and/or chronic cardiac complications.
[48] A method of preventing occurrence and/or reducing severity of one or more medical conditions resulting from COVID-19 and/or improving human body immunity in a subject in need thereof, comprises administering a therapeutically effective amount of the compound herbal composition.
[49] The one or more medical conditions may comprise pneumonia and/or acute respiratory syndrome and/or persistent pulmonary damage and/or post-viral fatigue and/or chronic cardiac complications.
[50] An effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica in the therapeutically effective combination for a medicinal version for a cold body constitution may comprise approximately 9 wt% of Angelica dahurica, approximately 4 wt% of Elsholtzia splendens, approximately 7.8 wt% of Lonicera japonica, approximately 12.5wt% of Glycine max, approximately 10 wt% Siraitia grosvenorii, approximately 10 wt% of Zingiber officinale, 10 % of Platycodon grandifloras, approximately 12 wt % of Imperata cylindrica, 5.0 wt% of Phragmites australis, 4.2 wt% of Allium cepa, approximately 10.3 wt% of Glycyrrhiza uralensis and 4.2 wt% of Prunus persica.
[51] The composition may further comprise Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, and Forsythia suspensa, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, and Forsythia suspensa in the therapeutically effective combination for a medicinal version for a subject having a cold body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 10 wt% of Platycodon grandifloras, approximately 12 wt % of Imperata cylindrica, approximately 5.0 wt% of Phragmites australis, approximately 4.2 wt% of Allium cepa, approximately 10.3 wt % of Glycyrrhiza uralensis, approximately 4.2 wt% of Prunus persica, approximately 5.9 wt% Tetradium ruticarpum, approximately 4.8 wt% Alpinia oxyphylla, approximately 5.4 wt% Cullen corylifolium, approximately 5.2 wt% Cornus officinalis, approximately 3.6 wt% Scutellaria baicalensis, and approximately 3.5 wt% Forsythia suspensa.
[52] The composition may further comprise Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Dolichos lablab, and Coix lachryma-jobi, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica,
Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Dolichos lablab, and Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a cold body constitution that may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 8.7 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 5.7 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 5.7 wt% of Tetradium ruticarpum, approximately 4.8 wt% of Alpinia oxyphylla, approximately 5.2 wt% of Cullen corylifolium, approximately 5.2 wt% of Cornus officinalis, approximately
2.6 wt% of Dolichos lablab, and approximately 4.8 wt% Coix lachryma-jobi.
[53] The composition may further comprise Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale(Dry), Alpinia oxyphylla in the therapeutically effective combination for a dietary version for a subject having a cold body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately
8.7 % of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately approximately 5.7 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 1.1 wt% of Agastache rugosa, approximately 7.3 wt% of Myristica fragrans, approximately 1 .5 wt% of Cinnamomum cassia, approximately 11.1 wt% of Zingiber officinale(Dry) and approximately 7.3 wt% of Alpinia oxyphylla.
[54] The composition may further comprise Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica,
Foeniculum vulgare, Zanthoxylum bungeanum, Zingiber officinale(Dry), Astragalus membranaceus, Agastache rugosa, Dolichos lablab, and Coix lachryma-jobi in the therapeutically effective combination for dampness resolving dietary version for a subject having a cold body constitution and may comprise approximately 6.8 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 5.9 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, approximately 9.1 % of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt% of Allium cepa, approximately 7.8 wt% of Glycyrrhiza uralensis, approximately 3.2 wt% of Prunus persica, approximately 4.6 wt% of Foeniculum vulgare, approximately 4.6 wt% of Zanthoxylum bungeanum, approximately 4.6 wt % of Zingiber officinale(Dry), approximately 6.8 wt% of Astragalus membranaceus, approximately 1.4 wt% of Agastache rugosa, approximately 2.8 wt% of Dolichos lablab, and approximately 5.0 wt% of Coix lachryma-jobi.
[55] The composition may further comprise Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa in the therapeutically effective combination for a medicinal version for a subject having a hot body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.3 wt % of Chrysanthemum indicum, approximately 4.7 wt% of Taraxacum mongolicum, approximately 4.2 wt% of Viola yedoensis, approximately 4.3 wt% of Begonia fimbristipula, approximately 4.3 wt% Scutellaria baicalensis, and approximately 4.3 wt% of Forsythia suspensa.
[56] The composition of claim 1 , may further comprise Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a hot body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of
Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.3 wt % of Chrysanthemum indicum, approximately 4.7 wt% of Taraxacum mongolicum, approximately 4.2 wt% of Viola yedoensis, approximately 2.6 wt% of Dolichos lablab, and approximately 6.1wt% of Coix lachryma-jobi.
[57] The composition may further comprise Scaphium scaphigerum, Chrysanthemum indicum, Taraxacum mongolicum, Houttuynia cordata, Gardenia jasminoides in the therapeutically effective combination for a dietary version for a subject having a hot body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.5 wt% of Scaphium scaphigerum, approximately 6.5 wt % of Chrysanthemum indicum, approximately 5.9 wt% of Taraxacum mongolicum, approximately 4.6 wt% of Houttuynia cordata, and approximately 4.8 wt% of Gardenia jasminoides.
[58] The composition may further comprise Gardenia jasminoides, Nelumbo nucifera, Lophatherum gracile, Houttuynia cordata , Agastache rugosa, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving dietary version for a subject having a hot body constitution and may comprise approximately 6.8 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, approximately 9.1 wt% of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt% of Allium cepa, approximately 7.8 wt% of Glycyrrhiza uralensis, approximately 3.2 wt% of Prunus persica, approximately 9.1 wt% of Gardenia jasminoides, approximately 2.7 wt% of Nelumbo nucifera, approximately 4.6 wt% of Lophatherum gracile, approximately 4.1 wt% of Houttuynia cordata , approximately 1.4
wt % of Agastache rugosa, approximately 2.7 wt% of Dolichos lablab, and approximately 5.0 wt% of Coix lachryma-jobi.
[59] The composition may further comprise Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, and Cornus officinalis in the therapeutically effective combination for a medicinal version for a subject having a weak body constitution and may comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 4.3 wt% of Dioscorea oppositifolia, approximately 13.0 wt% of Astragalus membranaceus, 1.1 wt% Cinnamomum cassia, 2.2 wt % of Zingiber officinale(Dry), 2.2 wt% of Amomum villosum, and 5.4 wt% Cornus officinalis.
[60] The composition may further comprise Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a weak body constitution and may comprise approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.3 wt% of Allium cepa, approximately 7.9 wt% of Glycyrrhiza uralensis, approximately 3.3 wt% of Prunus persica, approximately 4.7 wt% of Dioscorea oppositifolia, approximately 9.3 wt% of Astragalus membranaceus, approximately 1.2 wt% Cinnamomum cassia, approximately 1.2 wt % of Zingiber officinale(Dry), approximately 1.2 wt% of Amomum villosum, approximately 5.8 wt% Cornus officinalis, approximately 2.3 wt% of Dolichos lablab and approximately 4.7 wt% of Coix lachryma-jobi.
[61] The composition may further comprise Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a weak
body constitution that may comprise approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.3 wt% of Allium cepa, approximately 7.9 wt% of Glycyrrhiza uralensis, approximately 3.3 wt% of Prunus persica, approximately 4.7 wt% of Dioscorea oppositifolia, approximately 9.3 wt% of Astragalus membranaceus, approximately 1.2 wt% Cinnamomum cassia, approximately 1.2 wt % of Zingiber officinale(Dry), approximately 1.2 wt% of Amomum villosum, approximately 5.8 wt% Cornus officinalis, approximately 2.3 wt% of Dolichos lablab and approximately 4.7 wt% of Coix lachryma-jobi.
[62] The composition may further comprise Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis in the therapeutically effective combination for a dietary version for a subject having a weak body constitution and comprise approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 5.4 wt% of Dioscorea oppositifolia, approximately 13 wt% of Astragalus membranaceus, approximately 1.1 wt% of Cinnamomum cassia, approximately 2.2 wt% of Zingiber officinale(Dry), approximately 2.2 wt% of Amomum villosum, and approximately 4.3 wt % of Cornus officinalis.
[63] The composition may further comprise Dioscorea oppositifolia, Euryale ferox, Amomum villosum, Astragalus membranaceus, Agastache rugosa, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving dietary version for a subject having a weak body constitution and may comprise approximately 6.9 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 5.9 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, 9.1 wt% of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2
wt% of Allium cepa, approximately 7.8 wt% of Glycyrrhiza uralensis, approximately 3.2 wt% of Prunus persica, approximately 4.6 wt % of Dioscorea oppositifolia, approximately 4.6 wt% Euryale ferox, approximately 2.3 wt% of Amomum villosum, approximately 9.1 wt% of Astragalus membranaceus, approximately 1.4 wt% of Agastache rugosa, approximately 2.7 wt% of Dolichos lablab, and approximately 5.0 wt% of Coix lachryma- jobi.
[64] Other aspects of the invention are also disclosed.
Field of the Invention
[65] The present invention relates to a compound herbal composition for treatment of COVID- 19, symptoms of COVID-19 and/or other respiratory conditions.
[66] For example, the present invention also relates to compound herbal composition for prevention and treatment of pneumonia, lung complications, acute respiratory syndrome, persistent pulmonary damage, post-viral fatigue, and chronic cardiac complications resulted from virus infections such as COVID19.
[67] The present invention also relates to a compound herbal composition for the prevention and treatment of symptoms caused by viral infections including fever, headache, cough, chills, muscle aches and pains, fatigue, stomach conditions and difficulty in breathing.
Description of Embodiments
[68] The present invention comprises a foundation formulation comprising:
Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandiflorus, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica.
[69] The invention provides formulations suitable for three types of body constitutions and is optimised for Australian geographic and demographic conditions.
[70] Described below are 12 different variations of the formulation. The 12 different variations are categorized according to four body types.
[71] If there are significant physical and/or psychological stressors, the body can no longer keep its own bodily condition balanced and subsequently enter a state of “sub-health” (sub-optimal health). The compound herbal compositions are specially designed forthree different types of unhealthy body constitutions i.e. Heat, Cold, and Weak.
[72] As is known in the art of Chinese compound herbal medications, an “unhealthy” body constitution such as “Heat”, “Dampness-heat”, “Cold”, “Cold-dampness”, “Weak”, “Weak-dampness”, and “Heat- or Cold- dryness” is characterised by subnormal body temperature and other clinical manifestations.
[73] The Dampness resolving variants can sorted into the Qu Shi Pai Du decoction range, and the others under Qing Fei Pai Du decoction range.
[74] Variants for the four body types comprise: medicinal version, dampness resolving medicinal version, dietary version and dampness resolving dietary version.
[75] In an example of a therapeutically effective compound herbal composition, the foundation formulation comprises: Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonica 1 ,3g, Glycine max2.0, Siraitia grosvenorii 1 ,7g, Zingiber officinale 1 ,7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1 .7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g.
[76] Twelve types of formulations with their relative weights are set out below:
[77] Cold Body Constitution
[78] Medicinal version:
[79] The medicinal version of the compound herbal composition comprises Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, and Forsythia suspensa in addition to the foundation formulation.
[80] An effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, and Forsythia suspensa in the therapeutically effective combination for a medicinal version for a subject having a cold body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 10 wt% of Platycodon grandifloras, approximately 12 wt % of Imperata cylindrica, approximately 5.0 wt% of Phragmites australis, approximately 4.2 wt% of Allium cepa, approximately 10.3 wt % of Glycyrrhiza uralensis, approximately 4.2 wt% of Prunus persica, approximately 5.9 wt% Tetradium
ruticarpum, approximately 4.8 wt% Alpinia oxyphylla, approximately 5.4 wt% Cullen corylifolium, approximately 5.2 wt% Cornus officinalis, approximately 3.6 wt% Scutellaria baicalensis, and approximately 3.5 wt% Forsythia suspensa.
[81] An example of a therapeutically effective compound herbal composition of a medicinal version for a subject having a cold body constitution is as follows:
Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1 ,7g, Zingiber officinale 1 ,7g, Platycodon grandifloras 2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Tetradium ruticarpum 1 ,35g, Alpinia oxyphylla 1.1g, Cullen corylifolium 1.23g, Cornus officinalis 1.2g, Scutellaria baicalensis 0.82g, Forsythia suspensa 0.8g, maltodextrin.
[82] Dampness resolving medicinal version:
[83] The dampness resolving medicinal version of the compound herbal composition comprises Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Dolichos lablab, and Coix lachryma-jobi in addition to the foundation formulation.
[84] An effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Dolichos lablab, and Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a cold body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 8.7 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 5.7 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 5.7 wt% of Tetradium ruticarpum, approximately 4.8 wt% of Alpinia oxyphylla, approximately 5.2 wt% of Cullen corylifolium, approximately 5.2 wt% of Cornus officinalis, approximately 2.6 wt% of Dolichos lablab, and approximately 4.8 wt% Coix lachryma-jobi.
[85] An example of a therapeutically effective compound herbal composition for a dampness resolving medicinal version for a subject having a cold body constitution is as follows:
Angelica dahurica 1 ,5g, Elsholtzia splendens 0.7g, Lonicera japonican 1 ,3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Tetradium ruticarpum 1 .3g, Alpinia oxyphylla 1.1g, Cullen corylifolium 1 ,2g, Cornus officinalis 1 ,2g, Dolichos lablab 0.6g, Coix lachryma-jobi 1.1g, maltodextrin.
[86] Dietary version:
[87] The dietary version of the compound herbal composition comprises Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla.
[88] An effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale(Dry), Alpinia oxyphylla in a therapeutically effective combination for a dietary version for a subject having a cold body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately approximately 5.7 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 1.1 wt% of Agastache rugosa, approximately 7.3 wt% of Myristica fragrans, approximately 1.5 wt% of Cinnamomum cassia, approximately 11 .1 wt% of Zingiber officinale(Dry) and approximately 7.3 wt% of Alpinia oxyphylla.
[89] An example of a therapeutically effective compound herbal composition for a dietary version for a subject having a cold body constitution is as follows:
Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1 .7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g,
Prunus persica 0.7g, Agastache rugosa 0.25g, Myristica fragrans 1.68g, Cinnamomum cassia 0.34g, Zingiber officinale(Dry) 2.55g, Alpinia oxyphylla 1 ,68g, maltodextrin
[90] Dampness resolving dietary version:
[91] The dampness resolving dietary version of the compound herbal composition comprises Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla in addition to the foundation formulation.
[92] An effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras, Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Foeniculum vulgare, Zanthoxylum bungeanum, Zingiber officinale(Dry), Astragalus membranaceus, Agastache rugosa, Dolichos lablab, and Coix lachryma-jobi in the therapeutically effective combination for dampness resolving dietary version for a subject having a cold body constitution comprises approximately 6.8 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 5.9 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, approximately 9.1 % of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt% of Allium cepa, approximately 7.8 wt% of Glycyrrhiza uralensis, approximately 3.2 wt% of Prunus persica, approximately 4.6 wt% of Foeniculum vulgare, approximately 4.6 wt% of Zanthoxylum bungeanum, approximately 4.6 wt % of Zingiber officinale(Dry), approximately 6.8 wt% of Astragalus membranaceus, approximately 1.4 wt% of Agastache rugosa, approximately 2.8 wt% of Dolichos lablab, and approximately 5.0 wt% of Coix lachryma-jobi.
[93] An example of a therapeutically effective combination for dampness resolving dietary version of a compound herbal composition for a subject having a cold body constitution is as follows:
Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1 .7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Foeniculum vulgare 1.0g, Zanthoxylum bungeanum 1.0g, Zingiber officinale(Dry) 1.0g, Astragalus membranaceus 1.5g, Agastache rugosa0.3g, Dolichos lablab 0.6g, Coix lachryma-jobi 1 .1g, maltodextrin
[94] Heat Body Constitution
[95] Medicinal version:
[96] A medicinal version of a compound herbal composition for a subject having a hot body constitution comprises Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa in addition to the foundation formulation.
[97] A therapeutically effective combination for a medicinal version of a compound herbal composition for a subject having a hot body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.3 wt % of Chrysanthemum indicum, approximately 4.7 wt% of Taraxacum mongolicum, approximately 4.2 wt% of Viola yedoensis, approximately 4.3 wt% of Begonia fimbristipula, approximately 4.3 wt% Scutellaria baicalensis, and approximately 4.3 wt% of Forsythia suspensa.
[98] An example of a therapeutically effective combination for a medicinal version of a compound herbal composition for a subject having a hot body constitution is as follows:
[99] Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0g, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1 ,7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Chrysanthemum indicum 1 .45g, Taraxacum mongolicum 1.08g, Viola yedoensis 0.96g, Begonia fimbristipula 1.0g, Scutellaria baicalensis 1.0g, Forsythia suspensa 1 .0g, maltodextrin.
[100] Dampness resolving medicinal version:
[101 ] A Dampness resolving medicinal version for a subject having a hot body constitution comprises: Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa.
[102] A therapeutically effective combination for a dampness resolving medicinal version for a subject having a hot body constitution comprises approximately 6.5 wt%
of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.3 wt % of Chrysanthemum indicum, approximately 4.7 wt% of Taraxacum mongolicum, approximately 4.2 wt% of Viola yedoensis, approximately 2.6 wt% of Dolichos lablab, and approximately 6.1wt% of Coix lachryma-jobi.
[103] An example of a therapeutically effective combination for a dampness resolving medicinal version for a subject having a hot body constitution is as follows:
Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Chrysanthemum indicum 1.45g, Taraxacum mongolicum 1.08g, Viola yedoensis 0.96g, Begonia fimbristipula 1.0g, Dolichos lablab 0.6g, Coix lachryma-jobi 1 ,41g, maltodextrin.
[104] Dietary version:
[105] A dietary version for a subject having a hot body constitution comprises Scaphium scaphigerum, Chrysanthemum indicum, Taraxacum mongolicum, Houttuynia cordata, Gardenia jasminoides in addition in addition to the foundation formulation.
[106] A therapeutically effective combination for a dietary version for a subject having a hot body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.5 wt% of Scaphium scaphigerum, approximately 6.5 wt % of Chrysanthemum indicum, approximately 5.9 wt% of Taraxacum mongolicum, approximately 4.6 wt% of Houttuynia cordata, and approximately 4.8 wt% of Gardenia jasminoides.
[107] An example of a therapeutically effective combination for a dietary version for a subject having a hot body constitution is as follows:
Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1 .7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Scaphium scaphigerum 1 ,5g, Chrysanthemum indicum 1.5g, Taraxacum mongolicum 1 .35g, Houttuynia cordata 1 .05g, Gardenia jasminoides 1.1 g, maltodextrin.
[108] Dampness resolving dietary version:
[109] A Dampness resolving dietary version comprises Gardenia jasminoides, Nelumbo nucifera, Lophatherum gracile, Houttuynia cordata , Agastache rugosa, Dolichos lablab, Coix lachryma-job in addition to the foundation formulation.
[110] A therapeutically effective combination for a dampness resolving dietary version of a compound herbal composition for a subject having a hot body constitution comprises approximately 6.8 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, approximately 9.1 wt% of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt% of Allium cepa, approximately 7.8 wt% of Glycyrrhiza uralensis, approximately 3.2 wt% of Prunus persica, approximately 9.1 wt% of Gardenia jasminoides, approximately 2.7 wt% of Nelumbo nucifera, approximately 4.6 wt% of Lophatherum gracile, approximately 4.1 wt% of Houttuynia cordata , approximately 1.4 wt % of Agastache rugosa, approximately 2.7 wt% of Dolichos lablab, and approximately 5.0 wt% of Coix lachryma-jobi.
[111 ] An example of a therapeutically effective combination for a dampness resolving dietary version of a compound herbal composition for a subject having a hot body constitution is as follows:
[112] Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1 .7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1 ,7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Gardenia jasminoides 2.0g, Nelumbo
nucifera 0.6g, Lophatherum gracile 1.0g, Houttuynia cordata 0.9g, Agastache rugosa 0.3g, Dolichos lablab 0.6g, Coix lachryma-jobi 1.1g, maltodextrin.
[113] Weak Body Constitution
[114] Medicinal version:
[115] A medicinal version of a compound herbal composition for a subject having a weak body constitution comprises Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, and Cornus officinalis in addition to the foundation formulation.
[116] A therapeutically effective combination for a medicinal version of a compound herbal composition for a subject having a weak body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 4.3 wt% of Dioscorea oppositifolia, approximately 13.0 wt% of Astragalus membranaceus, 1.1 wt% Cinnamomum cassia, 2.2 wt % of Zingiber officinale(Dry), 2.2 wt% of Amomum villosum, and 5.4 wt% Cornus officinalis.
[117] An example of a therapeutically effective combination for a medicinal version of a compound herbal composition for a subject having a weak body constitution is as follows:
Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0g, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Dioscorea oppositifolia 1.0g, Astragalus membranaceus 3.0g, Cinnamomum cassia 0.25g, Zingiber officinale(Dry) 0.5g, Amomum villosum 0.5g, Cornus officinalis 1.25g, maltodextrin
[118] Dampness resolving medicinal version:
[119] A dampness resolving medicinal version of a compound herbal composition for a subject having a weak body constitution comprises Dioscorea oppositifolia, Astragalus
membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in addition to the foundation formulation.
[120] A therapeutically effective combination of a compound herbal composition for a dampness resolving medicinal version for a subject having a weak body constitution comprises approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.3 wt% of Allium cepa, approximately 7.9 wt% of Glycyrrhiza uralensis, approximately 3.3 wt% of Prunus persica, approximately 4.7 wt% of Dioscorea oppositifolia, approximately 9.3 wt% of Astragalus membranaceus, approximately 1.2 wt% Cinnamomum cassia, approximately 1 .2 wt % of Zingiber officinale(Dry), approximately 1 .2 wt% of Amomum villosum, approximately 5.8 wt% Cornus officinalis, approximately 2.3 wt% of Dolichos lablab and approximately 4.7 wt% of Coix lachryma-jobi.
[121 ] An example of a therapeutically effective compound combination for a dampness resolving medicinal version of a compound herbal composition for a subject having a weak body constitution is as follows:
Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0g, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1 .7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Dioscorea oppositifolia 1.0g, Astragalus membranaceus 2.0g, Cinnamomum cassia 0.25g, Zingiber officinale(Dry) 0.25g, Amomum villosum 0.25g, Cornus officinalis 1.25g, Dolichos lablab 0.5g, Coix lachryma-jobi 1.0g, maltodextrin
[122] Dietary version:
[123] A dietary version of a compound herbal composition for a subject having a weak body constitution comprises Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in addition to the foundation formulation.
[124] A therapeutically effective combination for a dietary version of a compound herbal composition for a subject having a weak body constitution comprises approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia
grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.3 wt% of Allium cepa, approximately 7.9 wt% of Glycyrrhiza uralensis, approximately 3.3 wt% of Prunus persica, approximately 4.7 wt% of Dioscorea oppositifolia, approximately 9.3 wt% of Astragalus membranaceus, approximately 1.2 wt% Cinnamomum cassia, approximately 1.2 wt % of Zingiber officinale(Dry), approximately 1 .2 wt% of Amomum villosum, approximately 5.8 wt% Cornus officinalis, approximately 2.3 wt% of Dolichos lablab and approximately 4.7 wt% of Coix lachryma-jobi.
[125] An example of a dietary version of a compound herbal composition for a subject having a weak body constitution is as follows:
Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0g, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1 .7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Dioscorea oppositifolia 1.25g, Astragalus membranaceus 3.0g, Cinnamomum cassia 0.25g, Zingiber officinale (Dry) 0.5g, Amomum villosum 0.5g, Cornus officinalis 1.0g, maltodextrin.
[126] Dampness resolving dietary version:
[127] A dampness resolving dietary version for a subject having a weak body constitution further comprises Dioscorea oppositifolia, Euryale ferox, Amomum villosum, Astragalus membranaceus, Agastache rugosa, Dolichos lablab, Coix lachryma-jobi.
[128] A therapeutically effective combination for a dampness resolving dietary version of a compound herbal composition for a subject having a weak body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 5.4 wt% of Dioscorea oppositifolia, approximately 13 wt% of Astragalus membranaceus, approximately 1.1 wt% of Cinnamomum cassia, approximately 2.2 wt% of Zingiber officinale(Dry), approximately 2.2 wt% of Amomum villosum, and approximately 4.3 wt % of Cornus officinalis.
[129] An example of a dampness resolving dietary version of the compound herbal composition for a subject having a weak body constitution is as follows:
Angelica dahurica 1.5g, Elsholtzia splendens 0.7g, Lonicera japonican 1.3g, Glycine max 2.0, Siraitia grosvenorii 1.7g, Zingiber officinale 1.7g, Platycodon grandiflorus2.0g, Imperata cylindrica 1.7g, Phragmites australis 0.8g, Allium cepa 0.7g, Glycyrrhiza uralensis 1.7g, Prunus persica 0.7g, Dioscorea oppositifolia 1.0g,Euryale ferox 1.0g, Amomum villosum 0.5g, Astragalus membranaceus 2.0g, Agastache rugosa 0.3g, Dolichos lablab 0.6g, Coix lachryma-jobi 1.1g, maltodextrin.
[130] The example compositions can include suitable additives. The 12 examples provided above include maltodextrin as an additive but it is envisaged that in other embodiments, other additives can be used.
[131] The compound herbal composition can be provided in any one of the following dosage forms: powdered form or tablet or capsule or paste or liquid form for oral consumption, or inhalants or injectable liquid.
[132] In some examples, the liquid form for oral consumption can be a concentrated or a diluted drink including water or other suitable dilutant.
[133] It can also be taken four times a day when the symptoms are in severe symptoms, take it every 3-4 hours.
In a hospital COVID patients were treated only with herbal compositions of the present invention. Out of 564 patients, 482 patients were recovered in 26 days, with a success rate of 85.5%. Patients under treatment did not suffer reinfection and their conditions were stabilised without other medical interventions, with fewer cases of persistent pulmonary damage and acute respiratory syndrome. On average, patient recovery time was shortened, with lower symptom deterioration rate, less cases of viral induced pneumonia and other pulmonary complications. No medical staff were suffered from COVID infections.
[134] Examples of the use of medicinal versions of the compositions for each of the Heat, Cold and Wet body constitutions are as follows.
[135] Example of using the composition for treatment of a patient with a Heat body constitution with dampness
[136] Symptoms of patient: Cough, yellow phlegm, sore throat, headache, mild fever, muscle pain, dry mouth, constipation and tiredness and sleepy for two days. Red tongue, Thick and greasy tongue coating, Floating and rapid and slippery pulse.
[137] Example Composition 1
[138] Dosage regimen: The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
[139] Results: After 2-3 days, the symptoms relieved. After 6-7 days, other symptoms disappeared except tiredness. The symptoms of tiredness disappeared in two weeks.
[140] Example of using the composition for treatment of a patient with a Cold body constitution with dampness
[141] Symptoms of patient: Cough, white phlegm, sore throat, dripping nose, headache, muscle pain, limbs cold, diarrhea, and tiredness sleepy for two days. White tongue, Thick and greasy tongue coating, Floating and slippery pulse.
[142] Example Composition 2
[144] Dosage regimen: The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
[145] Results: After 2-3 days, the symptoms relieved. After 6-7 days, other symptoms disappeared except tiredness. The symptoms of tiredness disappeared in two weeks. [146] Example of using the composition for treatment of a patient with a Weak body constitution with dampness
[147] Symptoms of patient:
[148] Cough with phlegm, sore throat, headache, spontaneous sweating muscle pain, poor appetite and weakness and sleepy for two days. Pale tongue, Thick and greasy tongue coating, Soft and slippery pulse.
[150] Dosage regimen: The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
[151] Results: After 2-3 days, the symptoms relieved. After 6-7 days, other symptoms disappeared except tiredness. The symptoms of tiredness disappeared in two weeks. [152] Example of using the composition for treatment of a patient with a Heat body constitution without dampness
[153] Symptoms of patient: Cough, sore throat, headache, mild fever, muscle pain, dry mouth, constipation anxiety and tiredness for two days. Red tongue, Floating and rapid and pulse.
[155] Dosage regimen: The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
[156] Results: After 2-3 days, the symptoms relieved. After 6-7 days, other symptoms disappeared except tiredness. The symptoms of tiredness disappeared in two weeks.
[157] Example of using the composition for treatment of a patient with a Cold body constitution without dampness
[158] Symptoms of patient:
[159] Cough, sore throat, dripping nose, headache, muscle pain, limbs cold, diarrhea, and tiredness for two days. White tongue, Thin white tongue coating, Floating tight pulse.
[161] Dosage regimen: The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
[162] Results: After 2-3 days, the symptoms relieved. After 6-7 days, other symptoms disappeared except tiredness. The symptoms of tiredness disappeared in two weeks. [163] Example of using the composition for treatment of a patient with a Weak body constitution without dampness
[164] Symptoms of patient:
[165] Cough, sore throat, headache, spontaneous sweating, muscle pain, poor appetite and weakness for two days. Light-whitish tongue coating, Floating and weak pulse. [166] Example Composition 6
[167] Dosage regimen: The patient took a single dose of granules of the composition twice a day. Each dose was taken approximately 30 minutes after a meal with boiled water.
[168] Results: After 2-3 days, the symptoms relieved. After 6-7 days, other symptoms disappeared except tiredness. The symptoms of tiredness disappeared in two weeks.
[169] Herbal formulations are provided which reduce the occurrence of viral infections and can prevent and treat complications associated with COVID-19.
[170] The invention provides compositions for use in treating COVID-19 or other viral infections, and/or one or more medical conditions resulting from COVID-19 in a subject in need thereof.
[171] The one or more medical conditions can comprise pneumonia and/or acute respiratory syndrome and/or persistent pulmonary damage and/or post-viral fatigue and/or chronic cardiac complications.
[172] The compound herbal compositions can prevent occurrence and/or reduce severity of one or more medical conditions resulting from COVID-19 and/or improve human body immunity.
[173] The compositions have been found to be effective in treating a range of symptoms including cough, fever, fatigue, difficulty in breathing, dry throat, bitterness in the mouth, and symptoms of mental exhaustion.
[174] These formulations can substantially reduce the possibility of organ deterioration and greatly increase survival rate.
Interpretation
Embodiments:
[175] Reference throughout this specification to “one embodiment” or “an embodiment” means that a particular feature, structure or characteristic described in connection with the embodiment is included in at least one embodiment of the present invention. Thus, appearances of the phrases “in one embodiment” or “in an embodiment” in various places throughout this specification are not necessarily all referring to the same embodiment, but may. Furthermore, the particular features, structures or characteristics may be combined in any suitable manner, as would be apparent to one of ordinary skill in the art from this disclosure, in one or more embodiments.
[176] Similarly, it should be appreciated that in the above description of example embodiments of the invention, various features of the invention are sometimes grouped together in a single embodiment, figure, or description thereof for the purpose of streamlining the disclosure and aiding in the understanding of one or more of the various inventive aspects. This method of disclosure, however, is not to be interpreted as reflecting an intention that the claimed invention requires more features than are expressly recited in each claim. Rather, as the following claims reflect, inventive aspects lie in less than all features of a single foregoing disclosed embodiment. Thus, the claims following the Detailed Description of Specific Embodiments are hereby expressly incorporated into this Detailed Description of Specific Embodiments, with each claim standing on its own as a separate embodiment of this invention.
[177] Furthermore, while some embodiments described herein include some but not other features included in other embodiments, combinations of features of different embodiments are meant to be within the scope of the invention, and form different embodiments, as would be understood by those in the art. For example, in the following claims, any of the claimed embodiments can be used in any combination.
Different Instances of Objects
[178] As used herein, unless otherwise specified the use of the ordinal adjectives “first”, “second”, “third”, etc., to describe a common object, merely indicate that different instances of like objects are being referred to, and are not intended to imply that the objects so described must be in a given sequence, either temporally, spatially, in ranking, or in any other manner.
Specific Details
[179] In the description provided herein, numerous specific details are set forth. However, it is understood that embodiments of the invention may be practiced without these specific details. In other instances, well-known methods, structures and techniques have not been shown in detail in order not to obscure an understanding of this description.
Comprising and Including
[180] In the claims which follow and in the preceding description of the invention, except where the context requires otherwise due to express language or necessary implication, the word “comprise” or variations such as “comprises” or “comprising” are used in an inclusive sense, i.e. to specify the presence of the stated features but not to preclude the presence or addition of further features in various embodiments of the invention.
[181 ] Any one of the terms: including or which includes or that includes as used herein is also an open term that also means including at least the elements/features that follow the term, but not excluding others. Thus, including is synonymous with and means comprising.
Scope of Invention
[182] Thus, while there has been described what are believed to be the preferred embodiments of the invention, those skilled in the art will recognize that other and further modifications may be made thereto without departing from the spirit of the invention, and it is intended to claim all such changes and modifications as fall within the scope of the invention. For example, any formulas given above are merely representative of procedures that may be used. Functionality may be added or deleted from the block diagrams and operations may be interchanged among functional blocks. Steps may be added or deleted to methods described within the scope of the present invention.
[183] Although the invention has been described with reference to specific examples, it will be appreciated by those skilled in the art that the invention may be embodied in many other forms.
Industrial Applicability
[184] It is apparent from the above, that the arrangements described are applicable to the alternative or herbal medication industries.
Claims
34
Claims
The claims defining the invention are as follows:
1. A compound herbal composition for treatment of or prevention of COVID-19 and/or treatment of or prevention of one or more of medical conditions resulting from COVID- 19, comprising:
Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Plat ycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica, wherein the composition is prepared by compounding a therapeutically effective combination of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica.
2. The composition of claim 1 further comprising Tetradium ruticarpum.
3. The composition of claim 1 further comprising Alpinia oxyphylla.
4. The composition of claim 1 further comprising Cullen corylifolium.
5. The composition of claim 1 further comprising Cornus officinalis.
6. The composition of claim 1 further comprising Scutellaria baicalensis.
7. The composition of claim 1 further comprising Forsythia suspensa.
8. The composition of claim 2 further comprising Dolichos lablab.
9. The composition of claim 1 further comprising Coix lachryma-jobi.
10. The composition of claim 1 further comprising an effective amount of each of Agastache rugosa.
11 . The composition of claim 1 further comprising Myristica fragrans.
12. The composition of claim 1 further comprising Cinnamomum cassia.
13. The composition of claim 1 further comprising Zingiber officinale.
14. The composition of claim 1 further comprising Foeniculum vulgare.
15. The composition of claim 1 further comprising Zanthoxylum bungeanum.
16. The composition of claim 1 further comprising Astragalus membranaceus.
17. The composition of claim 1 further comprising Chrysanthemum indicum.
18. The composition of claim 1 further comprising Taraxacum mongolicum.
19. The composition of claim 1 further comprising Viola yedoensis.
20. The composition of claim 1 further comprising Begonia fimbristipula.
21. The composition of claim 1 further comprising Scutellaria baicalensis.
22. The composition of claim 1 further comprising Forsythia suspensa.
35
23. The composition of claim 1 further comprising Scaphium scaphigerum.
24. The composition of claim 1 further comprising Houttuynia cordata.
25. The composition of claim 1 further comprising Gardenia jasminoides.
26. The composition of claim 1 further comprising, Nelumbo nucifera.
27. The composition of claim 1 further comprising Lophatherum gracile.
28. The composition of claim 1 further comprising Houttuynia cordata.
29. The composition of claim 1 further comprising Dioscorea oppositifolia.
30. The composition of claim 1 further comprising Amomum villosum.
31. The composition of claim 1 further comprising Cornus officinalis.
32. The composition of claim 1 further comprising Euryale ferox.
33. The composition of claim 1 , wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica in the therapeutically effective combination comprises between 6.5 wt% to 10wt% of Angelica dahurica, between 3 to 4.5 wt% of Elsholtzia splendens, between 5.5 wt% to 8 wt% of Lonicera japonica, between 8.5 wt% to 12.5wt% of Glycine max, between 7 wt% to 10.5wt% of Siraitia grosvenorii, between 7 wt% to 10.5 wt% of Zingiber officinale, between 8.5 wt% to 12.5% of Platycodon grandifloras, between 7.5 wt% to 10.5 wt % of Imperata cylindrica, between 3.0 wt% to 5.0 wt% of Phragmites australis, between 3.0 wt% to 4.5 wt% of Allium cepa, between 7 wt% to 10.5 wt% of Glycyrrhiza uralensis and between 3 wt% to 4.5 wt% of Prunus persica.
34. The composition of any one of claims 1 to 33, further comprising an additive.
35. The composition of claim 34 wherein the additive is maltodextrin.
36. The composition of any one of the above claims, wherein the compound herbal composition is provided in one of the following dosage forms: powdered form or tablet or capsule or paste or liquid form for oral consumption, or inhalants or injectable liquid.
37. The composition of claim 36, wherein the liquid form for oral consumption is a concentrated or a diluted drink.
38. Use of the compound herbal composition of any one of claims 1 to 33 in a therapeutically effective amount in the manufacture of a medicament for administration to a patient in the therapeutic treatment of and/or prevention of COVID-19 and/or treatment of and/or prevention of one or more of medical conditions resulting from COVID-19.
39. A method of treating COVID-19 and/or one or more medical conditions resulting from COVID-19 in a subject in need thereof, comprising administering a therapeutically effective amount of the compound herbal composition according to any one of claims 1 to 33.
40. The method of claim 39, wherein the one or more medical conditions comprise pneumonia and/or acute respiratory syndrome and/or persistent pulmonary damage and/or post-viral fatigue and/or chronic cardiac complications.
41. The composition of claim 1 , wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, and Prunus persica in the therapeutically effective combination for a medicinal version for a cold body constitution comprises approximately 9 wt% of Angelica dahurica, approximately 4 wt% of Elsholtzia splendens, approximately 7.8 wt% of Lonicera japonica, approximately 12.5wt% of Glycine max, approximately 10 wt% Siraitia grosvenorii, approximately 10 wt% of Zingiber officinale, 10 % of Platycodon grandifloras, approximately 12 wt % of Imperata cylindrica, 5.0 wt% of Phragmites australis, 4.2 wt% of Allium cepa, approximately 10.3 wt% of Glycyrrhiza uralensis and 4.2 wt% of Prunus persica.
42. The composition of claim 1 , further comprising Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, and Forsythia suspensa, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Scutellaria baicalensis, and Forsythia suspensa in the therapeutically effective combination for a medicinal version for a subject having a cold body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 10 wt% of Platycodon grandifloras, approximately 12 wt % of Imperata cylindrica, approximately 5.0 wt% of Phragmites australis, approximately 4.2 wt% of Allium cepa, approximately 10.3 wt % of Glycyrrhiza uralensis, approximately 4.2 wt% of Prunus persica, approximately 5.9 wt% Tetradium ruticarpum, approximately 4.8 wt% Alpinia oxyphylla, approximately 5.4 wt% Cullen corylifolium, approximately
5.2 wt% Cornus officinalis, approximately 3.6 wt% Scutellaria baicalensis, and approximately 3.5 wt% Forsythia suspensa. The composition of claim 1 , further comprising Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Dolichos lablab, and Coix lachryma-jobi, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Tetradium ruticarpum, Alpinia oxyphylla, Cullen corylifolium, Cornus officinalis, Dolichos lablab, and Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a cold body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3 wt% of Elsholtzia splendens, approximately
5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 8.7 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 5.7 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 5.7 wt% of Tetradium ruticarpum, approximately 4.8 wt% of Alpinia oxyphylla, approximately 5.2 wt% of Cullen corylifolium, approximately 5.2 wt% of Cornus officinalis, approximately 2.6 wt% of Dolichos lablab, and approximately 4.8 wt% Coix lachryma-jobi. The composition of claim 1 , further comprising Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale(Dry), Alpinia oxyphylla in the therapeutically effective combination for a dietary version for a subject having a cold body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately
8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately
38 approximately 5.7 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 1.1 wt% of Agastache rugosa, approximately 7.3 wt% of Myristica fragrans, approximately 1.5 wt% of Cinnamomum cassia, approximately 11.1 wt% of Zingiber officinale(Dry) and approximately 7.3 wt% of Alpinia oxyphylla. The composition of claim 1 , further comprising Agastache rugosa, Myristica fragrans, Cinnamomum cassia, Zingiber officinale (Dry), and Alpinia oxyphylla, wherein an effective amount of each of Angelica dahurica, Elsholtzia splendens, Lonicera japonica, Glycine max, Siraitia grosvenorii, Zingiber officinale, Platycodon grandifloras , Imperata cylindrica, Phragmites australis, Allium cepa, Glycyrrhiza uralensis, Prunus persica, Foeniculum vulgare, Zanthoxylum bungeanum, Zingiber officinale(Dry), Astragalus membranaceus, Agastache rugosa, Dolichos lablab, and Coix lachryma-jobi in the therapeutically effective combination for dampness resolving dietary version for a subject having a cold body constitution comprises approximately 6.8 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 5.9 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, approximately 9.1 % of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt% of Allium cepa, approximately 7.8 wt% of Glycyrrhiza uralensis, approximately 3.2 wt% of Prunus persica, approximately 4.6 wt% of Foeniculum vulgare, approximately 4.6 wt% of Zanthoxylum bungeanum, approximately 4.6 wt % of Zingiber officinale(Dry), approximately 6.8 wt% of Astragalus membranaceus, approximately 1 .4 wt% of Agastache rugosa, approximately 2.8 wt% of Dolichos lablab, and approximately 5.0 wt% of Coix lachryma-jobi. The composition of claim 1 , further comprising Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa in the therapeutically effective combination for a medicinal version for a subject having a hot body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica,
39 approximately 6.3 wt % of Chrysanthemum indicum, approximately 4.7 wt% of Taraxacum mongolicum, approximately 4.2 wt% of Viola yedoensis, approximately
4.3 wt% of Begonia fimbristipula, approximately 4.3 wt% Scutellaria baicalensis, and approximately 4.3 wt% of Forsythia suspensa.
47. The composition of claim 1 , further comprising Chrysanthemum indicum, Taraxacum mongolicum, Viola yedoensis, Begonia fimbristipula, Scutellaria baicalensis, Forsythia suspensa in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a hot body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately
7.4 wt% of Zingiber officinale, approximately 8.7 % wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.3 wt % of Chrysanthemum indicum, approximately 4.7 wt% of Taraxacum mongolicum, approximately 4.2 wt% of Viola yedoensis, approximately
2.6 wt% of Dolichos lablab, and approximately 6.1wt% of Coix lachryma-jobi.
48. The composition of claim 1 , further comprising Scaphium scaphigerum, Chrysanthemum indicum, Taraxacum mongolicum, Houttuynia cordata, Gardenia jasminoides in the therapeutically effective combination for a dietary version for a subject having a hot body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately
5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 6.5 wt% of Scaphium scaphigerum, approximately 6.5 wt % of Chrysanthemum indicum, approximately 5.9 wt% of Taraxacum mongolicum, approximately 4.6 wt% of Houttuynia cordata, and approximately 4.8 wt% of Gardenia jasminoides.
49. The composition of claim 1 , further comprising Gardenia jasminoides, Nelumbo nucifera, Lophatherum gracile, Houttuynia cordata , Agastache rugosa, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving dietary version for a subject having a hot body constitution comprises approximately 6.8 wt% of Angelica dahurica, approximately 3.2 wt% of
40
Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately
9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately 7.8 wt% of Zingiber officinale, approximately 9.1 wt% of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt% of Allium cepa, approximately 7.8 wt% of Glycyrrhiza uralensis, approximately 3.2 wt% of Prunus persica, approximately 9.1 wt% of Gardenia jasminoides, approximately 2.7 wt% of Nelumbo nucifera, approximately 4.6 wt% of Lophatherum gracile, approximately
4.1 wt% of Houttuynia cordata , approximately 1.4 wt % of Agastache rugosa, approximately 2.7 wt% of Dolichos lablab, and approximately 5.0 wt% of Coix lachryma-jobi. The composition of claim 1 , further comprising Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, and Cornus officinalis in the therapeutically effective combination for a medicinal version for a subject having a weak body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 4.3 wt% of Dioscorea oppositifolia, approximately 13.0 wt% of Astragalus membranaceus, 1.1 wt% Cinnamomum cassia, 2.2 wt % of Zingiber officinale(Dry), 2.2 wt% of Amomum villosum, and 5.4 wt% Cornus officinalis. The composition of claim 1 , further comprising Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a weak body constitution comprises approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.3 wt% of Allium cepa, approximately 7.9 wt% of Glycyrrhiza uralensis, approximately 3.3 wt% of Prunus persica, approximately 4.7 wt% of Dioscorea oppositifolia, approximately
41
9.3 wt% of Astragalus membranaceus, approximately 1 .2 wt% Cinnamomum cassia, approximately 1.2 wt % of Zingiber officinale(Dry), approximately 1.2 wt% of Amomum villosum, approximately 5.8 wt% Cornus officinalis, approximately 2.3 wt% of Dolichos lablab and approximately 4.7 wt% of Coix lachryma-jobi.
52. The composition of claim 1 , further comprising Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis, Dolichos lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving medicinal version for a subject having a weak body constitution comprises approximately 7.0 wt% of Angelica dahurica, approximately 3.3 wt% of Elsholtzia splendens, approximately 6.0 wt% of Lonicera japonica, approximately 9.3 wt% of Glycine max, approximately 7.9 wt% Siraitia grosvenorii, approximately 7.9 wt% of Zingiber officinale, 9.3 wt% of Platycodon grandifloras, approximately 7.9 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.3 wt% of Allium cepa, approximately 7.9 wt% of Glycyrrhiza uralensis, approximately 3.3 wt% of Prunus persica, approximately 4.7 wt% of Dioscorea oppositifolia, approximately 9.3 wt% of Astragalus membranaceus, approximately 1 .2 wt% Cinnamomum cassia, approximately 1.2 wt % of Zingiber officinale(Dry), approximately 1.2 wt% of Amomum villosum, approximately 5.8 wt% Cornus officinalis, approximately 2.3 wt% of Dolichos lablab and approximately 4.7 wt% of Coix lachryma-jobi.
53. The composition of claim 1 , further comprising Dioscorea oppositifolia, Astragalus membranaceus, Cinnamomum cassia, Zingiber officinale(Dry), Amomum villosum, Cornus officinalis in the therapeutically effective combination for a dietary version for a subject having a weak body constitution comprises approximately 6.5 wt% of Angelica dahurica, approximately 3.0 wt% of Elsholtzia splendens, approximately 5.7 wt% of Lonicera japonica, approximately 8.7 wt% of Glycine max, approximately 7.4 wt% Siraitia grosvenorii, approximately 7.4 wt% of Zingiber officinale, 8.7 wt% of Platycodon grandifloras, approximately 7.4 wt % of Imperata cylindrica, approximately 3.5 wt% of Phragmites australis, approximately 3.0 wt% of Allium cepa, approximately 7.4 wt% of Glycyrrhiza uralensis, approximately 3.0 wt% of Prunus persica, approximately 5.4 wt% of Dioscorea oppositifolia, approximately 13 wt% of Astragalus membranaceus, approximately 1.1 wt% of Cinnamomum cassia, approximately 2.2 wt% of Zingiber officinale(Dry), approximately 2.2 wt% of Amomum villosum, and approximately 4.3 wt % of Cornus officinalis.
54. The composition of claim 1 , further comprising Dioscorea oppositifolia, Euryale ferox, Amomum villosum, Astragalus membranaceus, Agastache rugosa, Dolichos
42 lablab, Coix lachryma-jobi in the therapeutically effective combination for a dampness resolving dietary version for a subject having a weak body constitution comprises approximately 6.9 wt% of Angelica dahurica, approximately 3.2 wt% of Elsholtzia splendens, approximately 5.9 wt% of Lonicera japonica, approximately 9.1 wt% of Glycine max, approximately 7.8 wt% Siraitia grosvenorii, approximately
7.8 wt% of Zingiber officinale, 9.1 wt% of Platycodon grandifloras, approximately 7.8 wt % of Imperata cylindrica, approximately 3.7 wt% of Phragmites australis, approximately 3.2 wt% of Allium cepa, approximately 7.8 wt% of Glycyrrhiza uralensis, approximately 3.2 wt% of Prunus persica, approximately 4.6 wt % of Dioscorea oppositifolia, approximately 4.6 wt% Euryale ferox, approximately 2.3 wt% of Amomum villosum, approximately 9.1 wt% of Astragalus membranaceus, approximately 1 .4 wt% of Agastache rugosa, approximately 2.7 wt% of Dolichos lablab, and approximately 5.0 wt% of Coix lachryma-jobi.
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