WO2022263469A1 - Appareil et procédé de lecture d'élément d'échantillon - Google Patents

Appareil et procédé de lecture d'élément d'échantillon Download PDF

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Publication number
WO2022263469A1
WO2022263469A1 PCT/EP2022/066226 EP2022066226W WO2022263469A1 WO 2022263469 A1 WO2022263469 A1 WO 2022263469A1 EP 2022066226 W EP2022066226 W EP 2022066226W WO 2022263469 A1 WO2022263469 A1 WO 2022263469A1
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WO
WIPO (PCT)
Prior art keywords
sample element
reading
transport device
sample
transport
Prior art date
Application number
PCT/EP2022/066226
Other languages
German (de)
English (en)
Inventor
Johannes Benedikt Wilhelm GROSS
Martin Huber
Ahmet KIENHÖFER
Andreas Scherer
Jochen SENG
Jochen Trocha
Original Assignee
Huber Automotive Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huber Automotive Ag filed Critical Huber Automotive Ag
Priority to EP22733121.2A priority Critical patent/EP4323774A1/fr
Publication of WO2022263469A1 publication Critical patent/WO2022263469A1/fr

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/67—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742—Type of codes
    • G01N2035/00752—Type of codes bar codes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00792—Type of components bearing the codes, other than sample carriers
    • G01N2035/00801—Holders for sample carriers, e.g. trays, caroussel, racks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00821—Identification of carriers, materials or components in automatic analysers nature of coded information
    • G01N2035/00831—Identification of carriers, materials or components in automatic analysers nature of coded information identification of the sample, e.g. patient identity, place of sampling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0429—Sample carriers adapted for special purposes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0429—Sample carriers adapted for special purposes
    • G01N2035/0432—Sample carriers adapted for special purposes integrated with measuring devices

Definitions

  • the present invention relates to a device for reading a sample element with a transport device for transporting the sample element and a positioning device for positioning the sample element on the transport device at a predetermined starting position.
  • the present invention relates to a method for reading a sample element by positioning the sample element on a transport device at a predetermined starting position and transporting the sample element with the transport device.
  • Such devices and methods are suitable for reading sample elements that undergo a physical or chemical reaction.
  • the sample of a sample element can harden or dry in a certain period of time. It is also possible for the sample of a sample element to react with light, for example, within a certain period of time, which is known from various photo processes.
  • a sample of a sample element can also show a chemical reaction, e.g. in the form of a color change, within a specified period of time. Such chemical reactions are often used in medical analyses.
  • lateral flow tests are carried out, among other things, so that a positive or negative result of the tested.
  • These lateral flow tests have the advantage that, if the person who has tested positive and is infected with a virus, you can react as quickly as possible and you can at least isolate the person who has been tested in a quarantine to counteract further spread of the virus.
  • Sample analyzes and in particular such lateral flow tests are often carried out using test cassettes or other sample elements mainly in the following order.
  • a sample is taken from the person to be tested by means of a smear, a blood sample or some other form of sampling, which is then enriched with a buffer solution in order, for example, to extract the proteins, protein components or other relevant components from the sample taken.
  • the released virus proteins represent the so-called "antigens”.
  • An antigen is a substance that causes a reaction of the immune system in the body. During this process, also known as the immune response, proteins are also formed that are specifically directed against the antigen. These are called "antibodies”.
  • the test cassette contains a substance that reacts with the contents of the sample, combines chemically or biologically and in this way visually indicates the presence of a specific substance. Similar to a pregnancy test, a colored line will appear. The letters “C” and “T” are almost always printed on them. “C” stands for "Control” and is intended to indicate that the test worked or is valid. This stripe should always be visible. If it is missing, the test is invalid. “T” stands for test. If this stripe appears, the test is considered positive. It can also appear lighter than the control strip.
  • the result can usually be read after a specified period of time, e.g. 15 minutes. Adherence to the reading time is important as the chemical bond is limited and the line may fade over time.
  • the time required eg 15 minutes
  • the time required for the evaluation of the test is manually monitored by medical and/or support staff to ensure the necessary adhere to the timeframe as precisely as possible.
  • the test person is then informed of the result. If the number of people to be tested is small, this procedure is still reasonably acceptable in terms of reliability and staff utilization. If a large number of tests have to be carried out, this procedure is very critical in terms of reliability and the personnel required very quickly reach their performance limits.
  • Document DE 10 2016 004 335 B4 discloses a transport device and a method for transporting objects from workstation to workstation in a production facility.
  • a number of object carrier elements containing the objects to be transported can be located on an object carrier.
  • Object carriers, including the objects, can remain at a single work station while the other object carriers continue to move.
  • document US Pat. No. 7,641,855 B2 describes a system for automatically storing and reprocessing patient samples in an automated clinical analyzer. A sample is stored in the automated analyzer under controlled conditions without the need for operator intervention.
  • the document US 2021/0285977 A1 shows an automated medical diagnostic system and an associated method.
  • the object of the present invention is to ensure reliable reading of sample elements using simple means.
  • a device for reading a sample element is provided with a transport device for transporting the sample element and a positioning device for positioning the sample element on the transport device at a predetermined starting position.
  • the sample element can be read, for example, optically in the visible range of the light. However, any other suitable radiation can also be used for reading. Under certain circumstances, a reading by means of ultrasound or by means of electric currents is also possible.
  • the sample element may include a container and a sample therein or thereon.
  • the sample itself can be solid or liquid, for example.
  • the sample element can also be, for example, a platelet-shaped carrier on which the sample is applied.
  • the sample on the support of the sample element is read by a suitable reading method (see above), for example in relation to a change resulting from a chemical reaction.
  • the positioning device serves to position the sample element on the transport device. This positioning can be done automatically or manually. It is important that the positioning takes place at the specified starting position on the transport device.
  • the positioning device can, for example, have a positioning aid in the form of an opening, a shaft or the like. An operator can position the sample element at the specific starting position on the transport device through the opening or the shaft.
  • the transport device is used to transport the sample element from the starting position to a predetermined reading position. At the specified reading position, the sample element is automatically read using a reading device.
  • the reading device contains, for example, a camera and a corresponding image processing device for processing recorded images.
  • the device for reading the sample element has a control device for activating the transport device in such a way that the sample element is transported from the specified starting position to the specified reading position in a specified period of time. It is therefore crucial that the sample element requires a fixed, predetermined time during transport from the predetermined starting position to the predetermined reading position. The sample element is thus stored on the transport device between the start and the reading. This means that the sample element is temporarily buffered by the transport device. This intermediate buffering can be 15 minutes, for example, in a rapid virus test. After 15 minutes, for example, the optimum time for reading a test strip is reached. Before the 15 minutes is the optimal Reaction result not yet achieved and after 15 minutes a decomposition process begins again.
  • a sample element eg a test cassette
  • it is then ready for reading at the reading position after the predetermined period of time.
  • An operator therefore no longer has to manually monitor an exact period of time between the sampling or sample application and the reading of the sample element. A more reliable reading of the sample elements or a more reliable evaluation of the samples can thus be ensured.
  • the transport device has a rotation carrier as a carrier for the sample element, preferably in the form of a circular disk, which can be rotated about its axis of rotation for transporting the sample element.
  • the disc does not have to be circular, but can also be polygonal or star-shaped, for example.
  • it is driven by a motor so that it rotates around its center or the axis of rotation. Slowly turning the disk at a speed that can be specified ensures that the sample element, starting from the starting position, reaches the reading position exactly in the specified time period.
  • the disk proves to be a very compact carrier of the transport device.
  • the transport device can have a conveyor belt as a carrier for the sample element, with which the sample element can be moved linearly from the specified starting position to the specified reading position.
  • the sample element on the conveyor belt performs a straight, linear movement from the starting position to the reading position.
  • the conveyor belt can also continue to run indefinitely.
  • the transport device has a plurality of receiving elements which are equally spaced from one another and which can each be equipped with a sample element.
  • a number of sample elements can be transported on the transport device at the same time.
  • This is the preferred rule here, which also applies to the variants according to the invention described above. Only for reasons of clarity has so far always been referred to as a sample element.
  • the transport device usually transports several sample elements from the starting position to the reading position at the same time.
  • the receiving elements can be simple holes if there is a perforated disk as a carrier for the sample elements.
  • the receiving elements can also contain mechanical components, for example to fix the sample elements on the carrier (disk or conveyor belt).
  • a receiving element can have a clamp or a magnet.
  • a receiving element can also be realized by a mere depression in the carrier.
  • the transport device is clocked as a function of the plurality of receiving elements and of the predetermined period of time.
  • the pane would therefore continue to rotate by a predetermined angle in a predetermined cycle, for example.
  • the disc continues to rotate by the specified angular amount so that the next sample element can be applied to the carrier at the starting position.
  • a conveyor belt as a carrier if it transports the sample elements in cycle operation. In this case, the conveyor belt moves on by a definable distance in each individual cycle.
  • This distance of further movement depends, of course, on the Total distance between the starting position and the reading position or from the total angle of rotation between the starting position and the reading position.
  • the timing also depends on the total number of recording elements or sample elements and the fixed time span. If, for example, the reading position is reached after 300° from the starting position, the transport between the two positions is to take 15 minutes and 30 sample positions are provided on the disc, the disc must continue to rotate by one recording position every 30 seconds, in this case an angular difference of 10° .
  • the carrier moves step by step in clocked operation, it can also move in a non-clocked manner, ie continuously at a constant speed, in an alternative embodiment.
  • the device has a cover for the transport device, with the transport device moving relative to the cover during transport.
  • the positioning device is part of the cover here and has a positioning opening through which the sample element can be positioned on the transport device at the starting position.
  • the cover can also be disc-shaped.
  • the positioning device can be incorporated into the cover, for example, as a funnel with the positioning opening.
  • the positioning opening in the cover serves to ensure that the starting position can be easily found or not missed by the operator, for example. Specifically, the operator only has to place the sample element on the transport device through the positioning opening.
  • the cover has a reading opening through which the sample element can be read at the reading position by the reading device. It is assumed here that the cover covers the transport device at the top. In this case, the cover could cover the entire pane, ie the entire carrier of the transport device, and corresponding openings are preferably only provided at the reading position and at the start position in order to load the transport device or read out the samples. Alternatively, the reading of the sample elements from the the lower or opposite side of the pane. In this case, the cover does not have to have an additional reading opening.
  • the device has a removal device in the transport direction after the reading position, the sample element being able to be automatically removed from the transport device with the removal device.
  • the carrier of the transport device moves on in the transport direction, i.e. in the direction in which the sample elements are transported.
  • the sample elements that have been read off are to be removed from the transport device.
  • the sample elements are discarded after reading.
  • the device can have special disposal means.
  • the sample elements can be removed from the transport device by a moving mechanism (e.g. gripper).
  • the removal device can be realized by a deflection roller of the conveyor belt, with a sample element at the end of the conveyor belt tipping over and possibly being caught by a waste container.
  • the reading device for reading the sample element preferably has an optical sensor.
  • This optical sensor can be a camera, in particular with a two-dimensional image sensor or with a line sensor.
  • a transmitted light method or a reflected light method can be used for reading.
  • the wavelength range of the sensor or multiple sensors can be adjusted according to needs.
  • Fig. 1 is a schematic representation of an inventive
  • Fig. 2 is a schematic representation of a perforated disk
  • Fig. 3 is an isometric view of an exemplary device for
  • the following buffering and reading method or a corresponding reading device with a clocked transport disc (hereinafter also referred to as “rotary clock”) is proposed as an exemplary embodiment.
  • the test cassette also called test strips
  • this test cassette with sample, also referred to as sample element in the present document
  • the rotary indexer is preferably equipped with a rotating perforated disk, which makes it possible to accommodate a large number of test cassettes.
  • the rotary movement of the perforated disc in the housing of the rotary indexer then gradually transports the test strip from the insertion position, ie starting position, in the rotary indexer to the position for reading, ie reading position, the test result.
  • the test result is preferably read by an attached camera or by means of a scanner.
  • the result read could be transmitted directly to a cloud-based IT system, preferably via an existing network connection, which then digitally transmits the result to the person tested, preferably via an iOS or Android application on a smartphone.
  • the size (diameter) of the perforated disk, the number of recesses it contains (for inserting and transporting test cassettes) and the cycle time are used to determine how many test cassettes can be temporarily buffered and what throughput is possible with a given reaction time, e.g. per hour.
  • the throughput can be multiplied, for example, by making it possible to place a number of test cassettes in parallel in corresponding receiving positions on the disc or on the conveyor belt.
  • the perforated disk is preferably equipped with the greatest possible number of insertion pockets, which are always arranged at the same radial distance angle around the center point of the perforated disk.
  • the perforated disk is equipped with a total of 30 insertion pockets, which are arranged radially at the same angle of 12 degrees around the center point of the perforated disk.
  • the evaluation time is preferably 15 minutes or 900 seconds, this is divided by the number of remaining 27 insertion pockets. In the exemplary embodiment, this results in a cycle time of approximately 33.3 seconds.
  • the rotary cycler preferably has at least one sensor which can determine an exact cycle frequency or an exact cycle path through the positioning holes in the perforated disk and transmit this to the motor controller.
  • the information received by the motor controller from the sensor is processed by the motor controller in order to subsequently set the electric motor installed in the rotary indexer into rotary motion.
  • the direction of rotation of the motor and the perforated disk connected to it via the drive flange of the motor is preferably clockwise.
  • the diameter and the number of insert pockets should be as large as possible, and the radial distance angle, conversely, as small as possible.
  • the test result is read digitally on the test strips using a scanner and/or camera.
  • the scanner and/or the camera is preferably located in an electronics housing which is placed on the body of the rotary indexer.
  • the scanner and/or the camera is located, for example, on a holder provided for this purpose, which in turn is located on the scanner/camera housing.
  • a suitable illuminant in particular an LED illuminant, can preferably be attached to the holder of the scanner or the camera.
  • the scanner and/or the camera are preferably connected to the microcomputer located in the electronics housing via a signal cable.
  • the microcomputer can work offline or is permanently or temporarily connected to the Internet so that it can forward the data received from the scanner and/or the camera to a corresponding, preferably cloud-based, IT system.
  • Software specially developed for this system can be run on the microcomputer.
  • the drive of the rotary indexer is controlled via this software. The user can start the process, interrupt the process and read out any malfunctions that may occur via a display connected to the microcomputer.
  • the rotary indexer can also be switched off with an emergency stop switch in order to quickly interrupt operation if a malfunction occurs.
  • test cassette is preferably disposed of in a further cycle directly via an ejector located in the housing of the rotary cycler without further contact.
  • ejector located in the housing of the rotary cycler without further contact.
  • openings for this purpose e.g. A disposal bag and/or a disposal container is preferably attached to the housing base plate.
  • another circuit board is preferably installed in the exemplary embodiment according to the invention, which connects the aforementioned components to one another.
  • the invention relates, among other things, to a method 1 for the reliable reading of large numbers of test cassettes or sample elements of all types and their buffering until the end of the chemical evaluation or reaction time.
  • FIG. 1 shows a block diagram of a specific exemplary embodiment of the method 1 according to the invention for reliably reading test results on test cassettes.
  • the start button is pressed via the display with touch function in rotary indexer 2, for example.
  • the rotation carrier 31 eg perforated disk
  • the system is ready and the rotation carrier 31 (eg perforated disk) begins to rotate in the previously programmed direction of rotation 40 in a cycle sequence 75-103 in the single cycle time 105 shown in the exemplary illustration in FIG.
  • a smear 5 is taken from the test person 3 .
  • this swab 5 can be taken via the mouth and nose, more modern tests also allow a spit solution.
  • a buffer solution is then enriched with the smear or sampling 5 7.
  • a barcode relating to the test person is preferably stuck to the test strip 4 or the sample element 8.
  • the test cassette 4 is inserted 9 into the rotary indexer 2 according to the invention via the preferably built-in test strip insertion funnel 36.
  • This funnel 36 has a positioning opening and is part of a positioning device with which it is possible to place a respective sample element 4 at a starting position place.
  • a duration of 900 seconds is taken as a basis for the chemical reaction time of the test 104 .
  • the method step for evaluating the test strip 4 is identified by position 9 in FIG Manufacturer of the rapid tests specifies.
  • the total cycle time 104 can therefore also be above or below the 900 seconds mentioned in the exemplary embodiment.
  • the result of the rapid test and the barcode 15 associated therewith are preferably read out 11 from the test strip 4 by means of an optical sensor (scanner and/or camera).
  • the scanner and/or the camera preferably sends the scan and/or image data directly to the microcomputer 60.
  • the operating software 71 processes the scan and/or image data received and sends them to an Internet portal, preferably wirelessly via a network connection or via a network cable 12.
  • the Internet portal 12 sends the test results, preferably digitally as a test result by e-mail 11a and/or via the special application "Test result to iOS or Android device" 11 b to the relevant test person or authorized recipient 3
  • a cross-invention application for Android and iOS-based terminals can display the test results and save them for the test person 3 for further processing and use and display them when the application is called up.
  • 2 also shows an exemplary division of the rotation carrier 31 as a carrier of the sample elements and as part of the transport device.
  • the size of the rotation carrier 31 and the size of the rotary indexer 2 is variable, so that it is possible to transport more or fewer sample elements in a rotary indexer 2 at the same time.
  • the senor 28 via the positioning holes 39 in the rotary support 31, the sensor 28 detects the individual clocks 75-103 via the position of the perforated disc and sends this information via the circuit board 61 to the microcomputer 60.
  • the operating software 71 installed on the microcomputer 60 processes the information received and transmits a signal to the electric motor 32 via the circuit board 61 if a change in position is required.
  • This signal can mean, for example, that the electric motor 32 has to rotate in the direction of rotation 40 until the sensor 28 reaches the next position hole 39.
  • the number of positioning holes 39 corresponds to the number of cycles on the rotary support 31 .
  • FIG 3 shows an isometric overall view of an exemplary design of the rotary indexer 2.
  • the housing 16 of the rotary indexer 2 is shown with a base 70 so that the rotary indexer 2 can be set up freely.
  • the rotary indexer 2 can also be designed as a table-top device without a stand 70 .
  • An electronics housing 50 is preferably located above the rotary indexer housing 16.
  • the position of the electronics housing 50 can vary and can also be omitted entirely if the corresponding components in the electronics housing 50 are partly or also in other exemplary embodiments be installed entirely in the rotary transfer case 16 or similar.
  • Under the electronics housing 50 there can be a reading opening, not shown in FIG. 3, through which, for example, the camera 55 reads the sample elements 4 .
  • the insertion 9 of the test strip or sample element 4 in method 1 into the rotary indexer 2 can, as shown in the exemplary embodiment in FIG include.

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  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

L'invention concerne un appareil de lecture d'élément d'échantillon (4) comprenant - un dispositif de transport destiné à transporter l'élément d'échantillon (4) et - un dispositif de positionnement destiné à positionner l'élément d'échantillon (4) à un emplacement de départ prédéfini (75) sur le dispositif de transport, comprenant - un dispositif de lecture destiné à lire automatiquement l'élément d'échantillon (4) à un emplacement de lecture prédéfini (101) et - un dispositif de commande destiné à commander le dispositif de transport de sorte que l'élément d'échantillon (4) soit transporté de l'emplacement de départ prédéfini (75) à l'emplacement de lecture prédéfini (101) dans une période de temps prédéfinie (104), le dispositif de transport comportant, comme support pour l'élément d'échantillon (4), un support rotatif (31) qui, pour transporter l'élément d'échantillon (4), peut tourner autour de son axe de rotation.
PCT/EP2022/066226 2021-06-18 2022-06-14 Appareil et procédé de lecture d'élément d'échantillon WO2022263469A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP22733121.2A EP4323774A1 (fr) 2021-06-18 2022-06-14 Appareil et procédé de lecture d'élément d'échantillon

Applications Claiming Priority (2)

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DE102021115864.8 2021-06-18
DE102021115864.8A DE102021115864A1 (de) 2021-06-18 2021-06-18 Vorrichtung und Verfahren zum Ablesen eines Probenelements

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0353592B1 (fr) * 1988-08-02 1996-04-24 Abbott Laboratories Cartouche de réaction et carrousel pour analyseur d'échantillons biologiques
US20050163661A1 (en) * 2001-11-20 2005-07-28 Ziegler Walter M. Test strip analysis apparatus
US7641855B2 (en) 2006-08-25 2010-01-05 Siemens Healthcare Diagnostics Inc. System for automatically storing and reprocessing patient samples in an automatic clinical analyzer
DE102016004335B4 (de) 2016-04-13 2018-10-11 Fresenius Medical Care Deutschland Gmbh Transporteinrichtung und Verfahren zum Transport von Objekten von Arbeitsstation zu Arbeitsstation einer Produktionsanlage und Produktionsanlage zur Herstellung von Produkten mit einer derartigen Transporteinrichtung
US20210285977A1 (en) 2017-06-23 2021-09-16 Everyplace Labs, Inc. Automated Medical Diagnostic System and Method

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0353592B1 (fr) * 1988-08-02 1996-04-24 Abbott Laboratories Cartouche de réaction et carrousel pour analyseur d'échantillons biologiques
US20050163661A1 (en) * 2001-11-20 2005-07-28 Ziegler Walter M. Test strip analysis apparatus
US7641855B2 (en) 2006-08-25 2010-01-05 Siemens Healthcare Diagnostics Inc. System for automatically storing and reprocessing patient samples in an automatic clinical analyzer
DE102016004335B4 (de) 2016-04-13 2018-10-11 Fresenius Medical Care Deutschland Gmbh Transporteinrichtung und Verfahren zum Transport von Objekten von Arbeitsstation zu Arbeitsstation einer Produktionsanlage und Produktionsanlage zur Herstellung von Produkten mit einer derartigen Transporteinrichtung
US20210285977A1 (en) 2017-06-23 2021-09-16 Everyplace Labs, Inc. Automated Medical Diagnostic System and Method

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