WO2022257202A1 - 一种可均匀加温的输液输血设备、系统及其应用方法 - Google Patents

一种可均匀加温的输液输血设备、系统及其应用方法 Download PDF

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Publication number
WO2022257202A1
WO2022257202A1 PCT/CN2021/103415 CN2021103415W WO2022257202A1 WO 2022257202 A1 WO2022257202 A1 WO 2022257202A1 CN 2021103415 W CN2021103415 W CN 2021103415W WO 2022257202 A1 WO2022257202 A1 WO 2022257202A1
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Prior art keywords
infusion
electrode plate
electric field
blood transfusion
frequency
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PCT/CN2021/103415
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English (en)
French (fr)
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李安
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深圳英瑞生物科技有限公司
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Publication of WO2022257202A1 publication Critical patent/WO2022257202A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
    • A61M5/365—Air detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
    • H05B6/00—Heating by electric, magnetic or electromagnetic fields
    • H05B6/02—Induction heating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3368—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling

Definitions

  • the invention relates to the technical field of medical equipment, in particular to a transfusion and blood transfusion equipment, a system and an application method applied to the system.
  • Infusion or blood transfusion
  • the liquid medicine or blood directly enters the blood vessels of the human body through the infusion set from outside the body, but in some cases the temperature of the liquid medicine or blood is lower when it is just taken out (if necessary refrigerated environment), if the patient needs a large amount of infusion (or blood transfusion), it needs to be heated to avoid the impact of low temperature on the human body system. Therefore, it needs to be warmed up quickly before infusion.
  • the temperature cannot exceed 40-42 degrees Celsius, because too high a temperature may cause the liquid medicine to deteriorate, and protein denaturation and red blood cell destruction will occur in the blood.
  • the physiological phenomenon that cancer cells are less resistant to heat than normal cells can also be used to kill cancer cells after heating tissues.
  • hyperthermia has a good effect on reducing the risk of cancer metastasis, and healthy cells can survive hyperthermia while tumor cells cannot.
  • this large amount of infusion (or blood transfusion) is mainly divided into two heating methods.
  • the first one is to heat the infused medicinal solution or blood in a heating device before the infusion (or blood transfusion), and then heat the patient.
  • a relatively large water bath container is basically used to exchange heat with the liquid medicine or blood in the liquid medicine bag, which is extremely inconvenient to operate and easily causes pollution.
  • the most common heating method for infusion is to use heating equipment to heat the infusion tube, and the heating equipment heats it through a common resistance heating method.
  • the patent application number CN211068490U proposes a heating system for infusion and blood transfusion, which is mainly composed of a plurality of heating bags that jointly form a circuitous heating pipeline isolation part, and heating sheets arranged on the front and back sides, and has multiple temperature Sensors are used to monitor the temperature of the heated liquid.
  • This method still uses the traditional resistance heating method, because the liquid medicine and the heating source are blocked by the liquid medicine packaging, and the medicine liquid packaging is basically a polymer material, which is a poor conductor of heat.
  • the patent application number US2020/0001022A1 proposes an electromagnetic induction heating method.
  • the liquid medicine or blood flows through a specially made metal ring pipe, which also serves as a secondary inductor and also has a primary induction
  • the primary inductor is energized, the secondary inductor will be heated due to electromagnetic induction, and then the medicinal liquid or blood will be heated.
  • This method has high heating efficiency and rapid heating.
  • secondary sensors are manufactured and assembled as consumables, resulting in extremely high costs and increasing the burden on patients and society.
  • microwave heating due to the development of microwave heating, it can be considered to use microwave heating to heat the liquid medicine or blood to be infused.
  • the device has a shielded heating chamber, and the microwaves generated by the microwave generator convect the The liquid medicine or blood is heated, and the heating method is simple and rapid.
  • the heating will be uneven. In different positions in the heating chamber, the heating effect is different. Some places have been heated to exceed the required temperature, and some places have not yet reached the required temperature. The required temperature, resulting in the risk of deterioration of the liquid medicine or blood denaturation. Therefore, it is necessary to design a special shimming device to enable the microwave system to heat uniformly, which will lead to higher cost and higher risk of use of the device.
  • the first object of the present invention is to provide an infusion and blood transfusion device capable of achieving uniform temperature rise and heating, good uniform heating effect, low cost and low risk of use.
  • the second object of the present invention is to provide an infusion and blood transfusion system that can achieve uniform temperature rise and heating, has good uniform heating effect, low cost, and low risk of use.
  • the third object of the present invention is to provide an application method of an infusion and blood transfusion system that can heat up evenly, has high heating efficiency and rapid heating, and can reduce the burden on patients and the society.
  • the present invention provides a kind of infusion and blood transfusion equipment, including a main control system, a heating chamber, at least one high-frequency power supply, and a high-frequency electric field heating device, and the main control system is electrically connected to the high-frequency power supply , the output end of the high-frequency power supply is connected to the high-frequency electric field heating device, the high-frequency electric field heating device is placed in the heating chamber, and the main control system outputs a control signal to control the high-frequency electric field heating device.
  • the electric field heating device generates a high-frequency alternating electric field to uniformly heat the liquid to be heated;
  • the infusion and blood transfusion equipment also includes a temperature sensing unit connected to the main control system for temperature detection and sensing Signal.
  • the temperature sensing unit includes an infrared temperature sensor or an optical fiber temperature sensor.
  • the high-frequency electric field heating device includes a first electrode plate and a second electrode plate oppositely arranged, and the two output ends of the high-frequency power supply are respectively connected to the first electrode plate and the second electrode plate , the output terminal of the high-frequency power supply applies a high-frequency voltage between the first electrode plate and the second electrode plate, and generates a high-frequency alternating electric field between the first electrode plate and the second electrode plate.
  • the first electrode plate and the second electrode plate have the same or approximately the same area and shape in a projection direction perpendicular to the electric field.
  • the two adjacent surfaces of the first electrode plate and the second electrode plate that generate the high-frequency alternating electric field are planes and are placed parallel to each other.
  • the first electrode plate and the second electrode plate are circular or square metal plate electrodes placed parallel to each other.
  • first electrode plate and the second electrode plate are multiple sets of spaced and parallel placed structures, which may be multiple sets of spaced and parallel placed circular or square metal plate electrodes.
  • the first electrode plate and the second electrode plate are a combination of concentric annular electrodes distributed from inside to outside.
  • an insulating structure is provided between the first electrode plate, the second electrode plate and the heating chamber.
  • the present invention provides a uniformly warmable infusion and blood transfusion system, including the above-mentioned uniformly warmable infusion and blood transfusion equipment
  • the infusion and blood transfusion equipment includes a main control system, a heating chamber, at least one high high-frequency power supply, high-frequency electric field heating device, the main control system is electrically connected to the high-frequency power supply, the output end of the high-frequency power supply is connected to the high-frequency electric field heating device, and the high-frequency electric field heating device is placed on In the heating chamber, the main control system outputs a uniform heating signal to control the high-frequency electric field heating device to generate a high-frequency alternating electric field to heat the liquid to be heated;
  • the infusion and blood transfusion equipment also includes a temperature sensor unit, the temperature sensing unit is connected with the main control system, and is used to detect the temperature sensing signal;
  • the consumable structure used in conjunction with the infusion and blood transfusion equipment the consumable structure is composed of polymer materials, which includes pipeline and a heated
  • the infusion and blood transfusion equipment also includes a peristaltic pump for squeezing the liquid in the infusion line, the output of the peristaltic pump is controlled by the main control system, and the output end of the peristaltic pump passes through the infusion tube The air bubble sensor connected to the sensing unit.
  • the sensing unit includes a pressure sensor, the air bubble sensor and the temperature sensor, the pressure sensor is used to detect the liquid pressure in the infusion line, and send a first sensing signal to the Main control system; the air bubble sensor detects the size of the bubbles or the accumulated bubble volume in the liquid in the infusion pipeline, and sends a second sensing signal to the main control system; the temperature sensor is used to detect the temperature of the heated cavity temperature of the internal liquid, and send a third sensing signal to the main control system.
  • the present invention provides an application method of a uniformly heated infusion and blood transfusion system.
  • the infusion and blood transfusion system adopts the above-mentioned infusion and blood transfusion system.
  • the present invention provides a uniform heating infusion and blood transfusion equipment and system, which has a heating chamber, a first electrode plate, a second electrode plate and a high-frequency power supply are arranged in the heating chamber, the first electrode plate and the The second electrode plate is placed in parallel and connected to both ends of the high-frequency power supply.
  • a high-frequency alternating electric field will be generated between the first electrode plate and the second electrode plate, and the medicinal solution or blood flowing through the consumables It will be heated evenly by high-frequency alternating electric field.
  • the polar molecules in the heating chamber have intrinsic dipole moments.
  • the polar molecules When there is no external electric field, the polar molecules are arranged chaotically, the distribution probability of the intrinsic dipole moment vector in each direction is equal, the vector sum of the intrinsic dipole moments of all molecules is zero, and the entire medium remains electrically neutral; but under the action of the external electric field, Each polar molecule is rotated under the action of rotational torque in the electric field, and has a tendency to arrange along the direction of the electric field, resulting in orientation polarization (or dipole polarization). During this process, polar molecules vibrate and rub at high speed to generate heat energy, and the temperature rises.
  • the infusion equipment also has at least one temperature sensor, which can monitor the temperature of the heated medicinal solution or blood in real time.
  • the pipelines or container consumables used to transport liquid medicine or blood are generally made of polymer materials, such as medical PVC materials, which are non-polar molecules, and they rarely absorb the energy of high-frequency alternating electric fields. In the heated chamber, little or no heating occurs.
  • Fig. 1 is a schematic diagram of an embodiment of an evenly heated infusion and blood transfusion system according to the present invention.
  • Fig. 2 is a schematic structural view of a high-frequency electric field heating device in the first embodiment of a uniformly heated infusion and blood transfusion device according to the present invention.
  • Fig. 3 is a schematic diagram of an evenly heated infusion and blood transfusion device of the present invention with multiple groups of flat electrodes placed in parallel at intervals
  • Fig. 4 is a schematic structural diagram of a high-frequency electric field heating device in the second embodiment of a uniformly heated infusion and blood transfusion device according to the present invention.
  • Fig. 5 is a schematic diagram of the first structure of the heated chamber in an embodiment of a uniformly warmable infusion and blood transfusion system according to the present invention.
  • Fig. 6 is a schematic diagram of the second structure of the heated chamber in an embodiment of a uniformly heated infusion and blood transfusion system according to the present invention.
  • a uniformly heated infusion and blood transfusion device 200 of the present invention includes a main control system 214, a heating chamber 207, at least one high-frequency power supply 205, a high-frequency electric field heating device, the main control system 214 and high
  • the high-frequency power supply 205 is electrically connected, and the output end of the high-frequency power supply 205 is connected with the high-frequency electric field heating device.
  • the high-frequency electric field heating device is placed in the heating chamber 207, and the control signal is output by the main control system 214 to control the high-frequency electric field heating device.
  • a high-frequency alternating electric field is generated to uniformly heat the liquid to be heated.
  • the frequency of the high-frequency alternating electric field is in the range of 0.3 MHz to 3000 MHz.
  • the frequency of the high-frequency alternating electric field can be 6.78 MHz, 13.56 MHz, 27.12 MHz, 915 MHz and 2450 MHz.
  • the present invention proposes a uniformly heated infusion and blood transfusion equipment 200, which has at least one high-frequency power supply 205, and uses a high-frequency alternating electric field in the heating chamber 207 to heat the liquid medicine or blood.
  • the high-frequency power supply 205 can prompt the high-frequency electric field heating device to generate a high-frequency alternating electric field, and the medicinal liquid or blood placed in the heating chamber 207 will be uniformly heated by the electric field.
  • the infusion liquid in this embodiment can be medical liquid or blood or other liquid allowed by the doctor, and it is packaged in a sealed soft bag or an open bottle 2 .
  • the infusion and blood transfusion equipment 200 further includes a temperature sensing unit having a temperature sensor 203, and the temperature sensing unit is connected to the main control system 214 for detecting a temperature sensing signal.
  • the temperature sensor 203 of the temperature sensing unit includes an infrared temperature sensor or an optical fiber temperature sensor. It can be seen that, in order to avoid the influence of the high-frequency electric field, the temperature sensor 203 can be an infrared temperature sensor, or an optical fiber temperature sensor.
  • the high-frequency electric field heating device includes a first electrode plate 215 and a second electrode plate 216 that are oppositely arranged, and the two output ends of the high-frequency power supply 205 are respectively connected to the first electrode plate 215 and the second electrode plate 216 , the output terminal of the high-frequency power supply 205 applies a high-frequency voltage between the first electrode plate 215 and the second electrode plate 216 to generate a high-frequency alternating electric field between the first electrode plate 215 and the second electrode plate 216 .
  • first electrode plate 215 and the second electrode plate 216 have the same or approximately the same area and shape in the projection direction perpendicular to the electric field.
  • the two adjacent surfaces of the first electrode plate 215 and the second electrode plate 216 that generate the high-frequency alternating electric field are planes and are placed parallel to each other.
  • the first electrode plate 215 and the second electrode plate 216 have the same or similar area and shape in the direction perpendicular to the projected direction of the electric field.
  • the two adjacent surfaces of the first electrode plate 215 and the second electrode plate 216 that generate the high-frequency alternating electric field are planes and placed in parallel.
  • first electrode plate 215 and the second electrode plate 216 are circular or square metal plate electrodes placed parallel to each other. As shown in FIG. 2 , the first electrode plate 215 and the second electrode plate 216 are circular or square metal flat plates placed in parallel.
  • first electrode plate 215 and the second electrode plate 216 are multiple sets of spaced and parallel placed structures, and may be multiple sets of spaced and parallel placed circular or square metal plate structures, as shown in FIG. 3 .
  • an insulating structure 217 is provided between the first electrode plate 215 , the second electrode plate 216 and the heating chamber 207 to avoid high voltage breakdown or short circuit between the electrode plates and the heating chamber 207 .
  • the present invention proposes a uniformly heated infusion and blood transfusion device 200, which uses a high-frequency alternating electric field to heat the liquid medicine or blood for infusion, and has at least one high-frequency power supply 205, the high-frequency power supply 205
  • the first electrode plate 215 and the second electrode plate 216 are respectively connected to the two output ends of the two output ends, and the first electrode plate 215 and the second electrode plate 216 are placed in the heating chamber 207 .
  • the heating chamber 207 can be a metal shielding shell made of metal material, which can be shielded to prevent electromagnetic waves from leaking out.
  • the high-frequency power supply 205 works at a certain frequency, and can generate a high-frequency alternating electric field in the range of 0.3 MHz to 3000 MHz between the first electrode plate 215 and the second electrode plate 216 .
  • the heated cavity 11 of the consumable structure 10 is placed between two electrode plates, and the medical solution or blood flowing through the consumable structure 10 will be uniformly heated by the high-frequency alternating electric field.
  • the infusion and blood transfusion device 200 of this embodiment also has at least one temperature sensor 203, which can monitor the temperature of the heated medical solution or blood, and when it reaches a preset value, the device will stop heating.
  • the first electrode plate 315 and the second electrode plate 316 that generate a high-frequency alternating electric field may have a special structure, as shown in FIG. 4 , the first electrode plate 316
  • the first electrode plate 315 and the second electrode plate 316 are a combination of concentric ring electrodes distributed from the inside to the outside. Under the same conditions, the ring electrodes can build a larger heating area, so this structure can be better applied to small volume Where required.
  • a uniformly heated infusion and blood transfusion system provided by the present invention includes the above-mentioned uniformly heated infusion and blood transfusion equipment 200 (such as the uniformly heated infusion and blood transfusion equipment No. One embodiment) and the consumable structure 10 used in conjunction with the infusion and blood transfusion equipment 200.
  • the consumable material structure 10 is made of polymer material, which includes the infusion pipeline and the heated cavity communicated with the infusion pipeline, and the heated cavity is placed in the heating chamber 207 .
  • the consumable structure 10 of this embodiment can use standard injection pipelines, such as medical PVC and other polymer materials, which belong to non-polar molecules, and they rarely absorb the energy of the high-frequency alternating electric field. In the heating chamber 207, Little or no heating.
  • the high-frequency electric field heating device includes a first electrode plate 215 and a second electrode plate 216 that are oppositely arranged, and the two output ends of the high-frequency power supply 205 are respectively connected to the first electrode plate 215 and the second electrode plate 216 , the output terminal of the high-frequency power supply 205 applies a high-frequency voltage between the first electrode plate 215 and the second electrode plate 216 to generate a high-frequency alternating electric field between the first electrode plate 215 and the second electrode plate 216 .
  • the infusion and blood transfusion equipment 200 also includes a peristaltic pump 208 for squeezing the liquid in the infusion line.
  • the output of the peristaltic pump 208 is controlled by the main control system 214.
  • Air bubble sensor 201 connected to the sensing unit. It can be seen that the infusion and blood transfusion equipment 200 of this embodiment also has a peristaltic pump 208, which can allow the liquid medicine or blood to be infused into the patient's body quickly, so that the infusion line 13 can be filled with the infusion liquid more quickly, so as to Meet the requirements of large volume infusion.
  • the sensing unit includes a pressure sensor 202, an air bubble sensor 201 and a temperature sensor 203
  • the pressure sensor 202 is used to detect the liquid pressure in the infusion pipeline 13, and send the first sensing signal to the main control system 214
  • Bubble sensor 201 detects the size or cumulative volume of bubbles in the liquid in the infusion pipeline 13, and sends a second sensing signal to the main control system 214
  • the temperature sensor 203 is used to detect the temperature of the liquid in the heated cavity 11, and sends The third sensing signal is sent to the main control system 214 .
  • the infusion and blood transfusion equipment 200 of this embodiment has at least one temperature sensor 203, and the temperature sensor 203 can monitor the temperature of the heated medical solution or blood, and when the temperature reaches the preset value, the equipment will stop heating.
  • the infusion and blood transfusion equipment 200 also has a pressure sensor 202, which can monitor the pressure of the liquid medicine or blood in the pipeline in real time, and the main control system 214 compares the received pressure detection signal with the original setting When the pressure detection signal is greater than the preset pressure value, the main control system 214 controls the driving device to stop driving, so as to ensure the safety of the patient 1 during infusion.
  • the infusion and blood transfusion equipment 200 also has an air bubble sensor 201, which can monitor the air bubbles in the pipeline in real time, and when the air bubble signal is greater than the bubble preset value set by the main control system 214, the main The control system 214 controls the drive device to stop driving, and controls the alarm device 212 to send an alarm signal, thereby ensuring the safety of the patient 1 during infusion.
  • an air bubble sensor 201 can monitor the air bubbles in the pipeline in real time, and when the air bubble signal is greater than the bubble preset value set by the main control system 214, the main The control system 214 controls the drive device to stop driving, and controls the alarm device 212 to send an alarm signal, thereby ensuring the safety of the patient 1 during infusion.
  • the infusion and blood transfusion equipment 200 also includes an input device 209 for setting infusion parameters, a display device 210 for outputting display information, a cooling device 211 for heat dissipation, and an alarm device for outputting alarm signals. 212.
  • the power supply device 213 for outputting electric energy for the infusion system.
  • the input device 209, the display device 210, the cooling device 211, the alarm device 212, and the power supply device 213 are respectively connected to the main control system 214.
  • the infusion and blood transfusion equipment 200 of this embodiment also includes an input device 209 and a display device 210.
  • the input device 209 is responsible for setting specific infusion parameters
  • the display device 210 is responsible for displaying parameters, working status and alarm information. tube and LCD screen.
  • the display parameters in this embodiment include but are not limited to the set temperature value, the real-time temperature value of the liquid, the heating time, the pressure value, etc., all of which can be displayed on the display device 210 on the device and can be easily obtained by the user.
  • the infusion and blood transfusion equipment 200 of this embodiment also includes a heat dissipation device 211 to dissipate heat from the high-frequency power supply 205 to ensure its normal operation.
  • the heat dissipation device 211 may be a heat dissipation device 211 with heat dissipation capability such as a heat dissipation fan, so as to perform circulating ventilation and heat dissipation on the high frequency power supply 205 .
  • the infusion and blood transfusion equipment 200 of this embodiment also includes an alarm device 212, which can issue an alarm, including sound, image, or light, or a combination of both.
  • the infusion and blood transfusion equipment 200 of this embodiment also includes a power supply device 213, which provides energy for the entire system, and is used for automatic switching between power supply and internal battery power supply, power distribution management, and internal battery charge and discharge management.
  • the consumables 10 used in conjunction with the equipment mainly include an infusion line 13 through which liquid medicine or blood flows and a heated cavity 11 communicating with the infusion line 13.
  • the structure of the consumables used in conjunction with the above-mentioned equipment 10 mainly includes an infusion line 13 through which liquid medicine or blood flows and a heated chamber 11.
  • the heated chamber 11 has a certain shape or structure, which is placed in a heating chamber 207, and the liquid medicine flowing through the heated chamber 11 Or blood can be heated by a high frequency alternating electric field.
  • the consumable 10 has a filter 12 capable of filtering out foreign matter in the infusion liquid.
  • the puncture needle may bring some foreign matter such as rubber crumbs, and the foreign matter is filtered out by the filter 12 .
  • the heated cavity 11 may have a curved or spiral pipeline shape, such as a curved pipeline shape structure 11a and a spiral pipeline shape structure 11b. It can be seen that in order to increase the heated cavity 11 The volume of the heated cavity 11 may be in the shape of a curved or spiral pipeline.
  • the heated cavity 11 may also be a cavity with a larger volume (relative to the consumable pipeline), such as a flat circular structure 11c. It can be seen that due to the principle of high-frequency alternating electric field heating, the structure of the cavity does not need to be specified as a specific shape. Mainly meet the requirements of liquid medicine or blood delivery.
  • the present invention provides an application method of a uniformly heated infusion and blood transfusion system.
  • the infusion and blood transfusion system adopts the above-mentioned infusion and blood transfusion system.
  • the method includes the following steps:
  • the method includes the following steps: connect the consumable structure 10 to the infusion and blood transfusion equipment 200 that can be evenly heated, and fill the infusion line 13 with the prepared infusion liquid through the peristaltic pump 208; set the infusion parameters through the input device, and Start the equipment for high-frequency alternating electric field heating, and the main control system 214 outputs a control signal to control the high-frequency electric field heating device to generate a high-frequency alternating electric field to uniformly heat the liquid to be heated; when it is determined that the consumable structure 10 is connected, Start the infusion.
  • the high-frequency alternating electric field can be generated between the first electrode plate 215 and the second electrode plate 216 through the high-frequency power supply 205 working at a certain frequency, and the infusion liquid flowing into the heating chamber 207 can be controlled. heating.
  • the temperature of the liquid to be heated is monitored in real time by the temperature sensor 203, and when it reaches a preset value, the device stops heating.
  • the pressure sensor 202 is used to monitor the pressure of the liquid in the infusion line 13 in real time; during the infusion process, the bubble sensor 201 is used to monitor the size of the bubbles or accumulated bubbles in the infusion line 13 in real time capacity.
  • the consumable structure 10 is connected with the warmable infusion and blood transfusion equipment 200 to prepare for infusion of medical solution or blood, and the peristaltic pump 208 fills the infusion line 13 with the medical solution or blood.
  • the consumable structure 10 is connected to the patient 1 and the infusion is started.
  • the present invention provides a uniformly heated infusion and blood transfusion equipment 200 and system, which has a heating chamber 207, and the heating chamber 207 is provided with a first electrode plate 215, a second electrode plate 216 and a high-frequency power supply 205 , the first electrode plate 215 and the second electrode plate 216 are placed in parallel and connected to both ends of the high-frequency power supply 205.
  • the high-frequency power supply 205 is working, a high frequency will be generated between the first electrode plate 215 and the second electrode plate 216. Alternating electric field, the liquid medicine or blood flowing through the consumables will be uniformly heated by the high-frequency alternating electric field.
  • polar molecules in the heating chamber 207 have intrinsic dipole moments.
  • the polar molecules When there is no external electric field, the polar molecules are arranged chaotically, the distribution probability of the intrinsic dipole moment vector in each direction is equal, the vector sum of the intrinsic dipole moments of all molecules is zero, and the entire medium remains electrically neutral; but under the action of the external electric field, Each polar molecule is rotated under the action of rotational torque in the electric field, and has a tendency to arrange along the direction of the electric field, resulting in orientation polarization (or dipole polarization). During this process, polar molecules vibrate and rub at high speed to generate heat energy, and the temperature rises.
  • the infusion equipment also has at least one temperature sensor 203, which can monitor the temperature of the heated medical solution or blood in real time.
  • the pipelines or container consumables used to transport liquid medicine or blood are generally made of polymer materials, such as medical PVC materials, which are non-polar molecules, and they rarely absorb the energy of high-frequency alternating electric fields.
  • the heating chamber 207 there is no or little heating.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
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Abstract

一种可均匀加温的输液输血设备（200）、系统及其应用方法，该设备包括主控系统（214）、加热仓（207）、至少一个高频电源（205）和高频电场加热装置，主控系统（214）与高频电源（205）电连接，高频电源（205）的输出端与高频电场加热装置连接，高频电场加热装置放置于加热仓（207）内，由主控系统（214）输出控制信号，以控制高频电场加热装置产生高频交变电场来均匀加热需要加热的液体；还包括温度传感单元（203），温度传感单元（203）与主控系统（214）连接，用于检测温度传感信号。输液输血系统能够均匀升温加热，加热均匀效果好，加热效率高，成本低，使用风险低，可以减少患者及社会负担。

Description

一种可均匀加温的输液输血设备、系统及其应用方法 技术领域
本发明涉及医疗设备技术领域，尤其涉及一种输液输血设备、系统及应用于该系统的应用方法。
背景技术
输液(或输血)在临床治疗中相当广泛，在输液过程中药液或血液从体外通过输液器直接进入人体血管，但在某些情况下药液或血液刚拿出时温度较低(如需要冷藏的环境进行保存)，若患者需要大量输液(或输血)，则需要对其进行加温以避免低温对人体系统的冲击。因此输注前需要对其进行快速升温。但仍要注意其温度不能超过40～42摄氏度，因为过高的温度可能会导致药液变质，血液则会发生蛋白质变性和红细胞破坏。
进一步的，在癌症的治疗上也可以利用癌细胞较正常细胞不耐热的生理现象，将组织加热后杀死癌细胞。通过靶向血流中循环的癌细胞，热疗对减少癌症转移风险具有较好的效果，健康细胞可以在热疗中存活，而肿瘤细胞则无法存活。
目前这种大量输液(或输血)主要分为两种加热方法，第一种，就是在输液(或输血)前将被输注药液或血液放到加热设备中加热，加热后再进行对患者的输液(或输血)，但此种方式，基本均采用一个相对较大的水浴容器，同药液袋中的药液或血液进行热交换，操作极为不便，同时也易造成污染。
而最为常见的输液(或输血)加热方法就是采用加温设备对输液管进行加热，加温设备通过普通的电阻发热方式，对其进行加热。如专利申请号为CN211068490U的专利提出一种输液输血加温系统，主要由具有多个共同形成迂回曲折加温管道隔离部的加温袋，及正面反面设置的加热片组成，并具有多个温度传感器来监测被加热液体的温度，该方法仍采用了传 统电阻式加热的方式，因药液与加热源被药液包装阻隔，且药液包装基本上均为高分子材料，是热的不良导体，所以其加热效率不高，无法满足大量输液(输血)的要求，同时，加温袋制造困难，成本较高，也无形增加了社会负担。专利申请号为US2020/0001022A1的专利提出了一种电磁感应加热方法，药液或血液流经一个特殊制作的金属环形管道，该金属环形管道还做为次级感应器，同时还具有一个初级感应器，当初级感应器通电时，因电磁感应作用会使次级感应器加热，进而对药液或血液进行加热，此方法加热效率高，加温迅速。但次级感应器被作为耗材进行制造和组装，导致其具有极高的成本，增加了患者及社会的负担。
另外，因微波加热的发展，可以考虑采用微波加热的方式对所需输注的药液或血液进行加热，该装置具有一个带有屏蔽的加热仓，微波发生器产生的微波对流经加热仓的药液或血液进行加热，该方法加热简单，迅速。但因微波加热本身的特点，会导致加热具有不均匀性，在加热仓内的不同位置，其加热的效果是不同的，有的地方已经加热到超过所需温度了，有的地方还没有达到所需温度，从而导致药液变质或血液变性的风险。所以需要设计特殊的匀场装置，使微波系统能够均匀加热，这样会导致装置具有较高的成本以及较高的使用风险。
发明内容
本发明的第一目的是提供一种能够实现均匀升温加热，加热均匀效果好，成本低，使用风险低的输液输血设备。
本发明的第二目的是提供一种能够实现均匀升温加热，加热均匀效果好，成本低，使用风险低的输液输血系统。
本发明的第三目的是提供一种能够均匀升温加热，加热效率高，加温迅速，可以减少患者及社会负担的输液输血系统的应用方法。
为了实现上述第一目的，本发明提供的一种输液输血设备，包括主控系统、加热仓、至少一个高频电源、高频电场加热装置，所述主控系统与所述高频电源电连接，所述高频电源的输出端与所述高频电场加热装置连 接，所述高频电场加热装置放置于所述加热仓内，由所述主控系统输出控制信号，以控制所述高频电场加热生装置产生高频交变电场来均匀加热需要加热的液体；所述输液输血设备还包括温度传感单元，所述温度传感单元与所述主控系统连接，用于温度检测传感信号。
进一步的方案中，所述温度传感单元包括红外温度传感器或光纤温度传感器。
进一步的方案中，所述高频电场加热装置包括相对配置的第一电极板以及第二电极板，所述高频电源的两个输出端分别与所述第一电极板以及第二电极板连接，所述高频电源的输出端向所述第一电极板、第二电极板之间施加高频电压，在所述第一电极板、第二电极板之间产生高频交变电场。
更进一步的方案中，所述第一电极板、第二电极板在垂直于电场的投影方向上具有相同或近似相同的面积与形状。
更进一步的方案中，所述第一电极板与第二电极板在产生高频交变电场的两个相邻面为平面，且相互平行放置。
更进一步的方案中，所述第一电极板、第二电极板为相互平行放置的圆形或方形金属平板电极。
更进一步的方案中，所述第一电极板、第二电极板为多组间隔平行放置的结构，可以是多组间隔平行放置的圆形或方形金属平板电极。
更进一步的方案中，所述第一电极板、第二电极板为由内至外分布的同心环形电极组合。
更进一步的方案中，所述第一电极板、第二电极板与所述加热仓之间设有绝缘结构。
为了实现上述第二目的，本发明提供的一种可均匀加温的输液输血系统，包括上述的可均匀加温的输液输血设备，所述输液输血设备包括主控系统、加热仓、至少一个高频电源、高频电场加热装置，所述主控系统与所述高频电源电连接，所述高频电源的输出端与所述高频电场加热装置连 接，所述高频电场加热装置放置于所述加热仓内，由所述主控系统输出均匀加热信号，以控制所述高频电场加热生装置产生高频交变电场来加热需要加热的液体；所述输液输血设备还包括温度传感单元，所述温度传感单元与所述主控系统连接，用于检测温度传感信号；与所述输液输血设备配合使用的耗材结构，所述耗材结构为高分子材料构成，其包括与输液管路以及与输液管路连通的被加热腔，所述被加热腔放置于所述加热仓内。
进一步的方案中，所述输液输血设备还包括用于对输液管路内液体进行挤压的蠕动泵，所述蠕动泵由所述主控系统控制输出，所述蠕动泵的输出端通过输液管路连接至所述传感单元的气泡传感器。
更进一步的方案中，所述传感单元包括压力传感器、所述气泡传感器以及所述温度传感器，所述压力传感器用于检测输液管路内的液体压力，并发送第一传感信号至所述主控系统；所述气泡传感器检测输液管路内的液体中的气泡大小或者累积气泡容量，并发送第二传感信号至所述主控系统；所述温度传感器用于检测所述被加热腔内液体的温度，并发送第三传感信号至所述主控系统。
为了实现上述第三目的，本发明提供的一种可均匀加温的输液输血系统的应用方法，输液输血系统是采用上述的输液输血系统，所述方法包括以下步骤：将耗材结构与可均匀加温的输液输血设备进行连接，并通过蠕动泵将预备的输注液体充满输液管路；通过输入装置设定好输注参数，并启动设备进行高频交变电场加热，由主控系统输出控制信号，以控制高频电场加热生装置产生高频交变电场来均匀加热需要加热的液体；当确定耗材结构连接完毕后，启动输注。
由此可见，本发明提供了一种可均匀加温的输液输血设备及系统，其具有加热仓，加热仓内设有第一电极板、第二电极板以及高频电源，第一电极板和第二电极板平行放置并与高频电源两端连接，当高频电源工作时，在第一电极板及第二电极板之间会产生高频交变电场，流经耗材的药液或血液会被高频交变电场均匀加热。
其中，加热仓中的极性分子(例如药液或血液中的水分子)具有固有偶极矩。在无外电场时，极性分子混乱排列，固有偶极矩矢量各方向的分布几率相等，所有分子固有偶极矩的矢量和为零，整个介质仍保持电中性；但在外电场作用下，每个极性分子在电场中都受到转动力矩的作用而产生旋转，并且有沿电场方向排布的趋向，产生取向极化(或偶极极化)的现象。极性分子在此过程中高速震动摩擦而产生热能，温度升高。
同时，输液设备还具有至少一处温度传感器，可以对被加热的药液或血液温度进行实时监测。
同时，该设备配套使用用于输送药液或血液的管路或者容器耗材一般由高分子材料构成，如医用PVC材料，属于非极性分子，它们则极少吸收高频交变电场的能量，在加热仓中，不会或极少被加热。
附图说明
图1是本发明一种可均匀加温的输液输血系统实施例的原理图。
图2是本发明一种可均匀加温的输液输血设备第一实施例中高频电场加热装置的结构示意图。
图3是本发明一种可均匀加温的输液输血设备多组间隔平行放置的平板电极示意图
图4是本发明一种可均匀加温的输液输血设备第二实施例中高频电场加热装置的结构示意图。
图5是本发明一种可均匀加温的输液输血系统实施例中被加热腔的第一结构示意图。
图6是本发明一种可均匀加温的输液输血系统实施例中被加热腔的第二结构示意图。
以下结合附图及实施例对本发明作进一步说明。
具体实施方式
为使本发明实施例的目的、技术方案和优点更加清楚，下面将结合本发明实施例的附图，对本发明实施例的技术方案进行清楚、完整地描述。显然，所描述的实施例是本发明的一部分实施例，而不是全部的实施例。 基于所描述的本发明的实施例，本领域普通技术人员在无需创造性劳动的前提下所获得的所有其他实施例，都属于本发明保护的范围。
一种可均匀加温的输液输血设备第一实施例：
如图1所示，本发明的一种可均匀加温的输液输血设备200，包括主控系统214、加热仓207、至少一个高频电源205、高频电场加热装置，主控系统214与高频电源205电连接，高频电源205的输出端与高频电场加热装置连接，高频电场加热装置放置于加热仓207内，由主控系统214输出控制信号，以控制高频电场加热生装置产生高频交变电场来均匀加热需要加热的液体。其中，高频交变电场的频率为0.3MHz至3000MHz范围内，作为优选，高频交变电场的频率可以为6.78MHz、13.56MHz、27.12MHz、915MHz及2450MHz。
可见，本发明提出一种可均匀加温的输液输血设备200，其具有至少一个高频电源205，在加热仓207内采用高频交变电场对药液或血液进行加热该输液输血设备200，高频电源205可以促使高频电场加热装置产生高频交变电场，置入加热仓207内的药液或血液会被该电场进行均匀加热。
本实施例的输注液体可以采用药液或血液或医生允许使用的其他液体，为密封式的软袋包装或者为开放式的瓶体2。
在本实施例中，输液输血设备200还包括具有温度传感器203的温度传感单元，温度传感单元与主控系统214连接，用于检测温度传感信号。其中，温度传感单元的温度传感器203包括红外温度传感器或光纤温度传感器。可见，为避免高频电场的影响，温度传感器203可以为红外温度传感器，或光纤温度传感器。
在本实施例中，高频电场加热装置包括相对配置的第一电极板215以及第二电极板216，高频电源205的两个输出端分别与第一电极板215以及第二电极板216连接，高频电源205的输出端向第一电极板215、第二电极板216之间施加高频电压，在第一电极板215、第二电极板216之间产生高频交变电场。可见，加热仓207内具有第一电极板215、第二电极 板216以及高频电源205，当高频电源205工作时，在第一电极板215及第二电极板216之间会产生高频交变电场。
其中，第一电极板215、第二电极板216在垂直于电场的投影方向上具有相同或近似相同的面积与形状。
进一步的，第一电极板215与第二电极板216在产生高频交变电场的两个相邻面为平面，且相互平行放置。
可见，为保证产生的所需高频电场的均匀性，第一电极板215及第二电极板216在垂直于电场的投影方向上具有相同或近似的面积与形状。优选的，第一电极板215及第二电极板216在两个产生高频交变电场的相邻面为平面，且平行放置。
进一步的，第一电极板215、第二电极板216为相互平行放置的圆形或方形金属平板电极。如图2所示，第一电极板215与第二电极板216为平行放置的圆形或方形金属平板。
更进一步的，第一电极板215、第二电极板216为多组间隔平行放置的结构，可以是多组间隔平行放置的圆形或方形金属平板结构，如图3所示。
在本实施例中，第一电极板215、第二电极板216与加热仓207之间设有绝缘结构217，可以避免电极板同加热仓207之间高压击穿或短路。
具体的，本发明提出一种可均匀加温的输液输血设备200，其通过高频交变电场来加热用来输注的药液或血液，其具有至少一个高频电源205，高频电源205的两输出端分别接有第一电极板215及第二电极板216，第一电极板215及第二电极板216置于加热仓207中。
其中，加热仓207可以是由金属材料构成的金属屏蔽壳体，可以屏蔽以防止电磁波外泄。
其中，高频电源205以一定的频率工作，可以在第一电极板215及第二电极板216之间产生0.3MHz至3000MHz范围内的高频交变电场。耗材结构10的被加热腔11置于两个电极板之间，流经耗材结构10的药液 或血液会被高频交变电场均匀加热。
此外，本实施例的输液输血设备200还具有至少一处温度传感器203，温度传感器203可以实施监测被加热药液或血液的温度，当其达到预设值时，设备会停止加热。
一种可均匀加温的输液输血设备第二实施例：
在本实施例中，为了配合耗材结构10或者更有效的利用电场能量，产生高频交变电场的第一电极板315及第二电极板316可以具有特殊的结构，如图4所示，第一电极板315、第二电极板316为由内至外分布的同心环形电极组合，因在相同的条件下，环形电极可以构建更大的加热面积，所以此结构能够更好的应用于小体积要求的场合。
一种可均匀加温的输液输血系统实施例：
在本实施例中，如图1所示，本发明提供的一种可均匀加温的输液输血系统，包括上述的可均匀加温的输液输血设备200(如可均匀加温的输液输血设备第一实施例)以及与输液输血设备200配合使用的耗材结构10。其中，耗材结构10为高分子材料构成，其包括与输液管路以及与输液管路连通的被加热腔，被加热腔放置于加热仓207内。可见，本实施例的耗材结构10可以采用标准的注射管路，如医用PVC等高分子材料，属于非极性分子，它们则极少吸收高频交变电场的能量，在加热仓207中，不会或极少被加热。
在本实施例中，高频电场加热装置包括相对配置的第一电极板215以及第二电极板216，高频电源205的两个输出端分别与第一电极板215以及第二电极板216连接，高频电源205的输出端向第一电极板215、第二电极板216之间施加高频电压，在第一电极板215、第二电极板216之间产生高频交变电场。
在本实施例中，输液输血设备200还包括用于对输液管路内液体进行挤压的蠕动泵208，蠕动泵208由主控系统214控制输出，蠕动泵208的输出端通过输液管路13连接至传感单元的气泡传感器201。可见，本实施 例的输液输血设备200还具有蠕动泵208，蠕动泵208可以让药液或血液快速的输注入患者体内，使输液管路13内能够更快速被输注液体填充满，以满足大容量输注的要求。
在本实施例中，传感单元包括压力传感器202、气泡传感器201以及温度传感器203，压力传感器202用于检测输液管路13内的液体压力，并发送第一传感信号至主控系统214；气泡传感器201检测输液管路13内的液体中的气泡大小或者累积气泡容量，并发送第二传感信号至主控系统214；温度传感器203用于检测被加热腔11内液体的温度，并发送第三传感信号至主控系统214。
可见，本实施例的输液输血设备200具有至少一处温度传感器203，温度传感器203可以实施监测被加热药液或血液的温度，当其达到预设值时，设备会停止加热。
可见，在某些实施实例中，输液输血设备200还具有压力传感器202，压力传感器202可以实时监测管路内药液或血液的压力，主控系统214将接收到的压力检测信号与原先设定好的预设压力值进行比较，当压力检测信号大于预设压力值时，由主控系统214控制驱动装置停止驱动，从而保证患者1在输注时的安全。
可见，在某些实施实例中，输液输血设备200还具有气泡传感器201，气泡传感器201可以实时监测管路内的气泡，当气泡信号大于主控系统214设定的气泡预设值时，由主控系统214控制驱动装置停止驱动，并且控制报警装置212发出警报信号，从而保证患者1输注时的安全。
在本实施例中，输液输血设备200还包括用于设定输注参数的输入装置209、用于输出显示信息的显示装置210、用于散热的散热装置211、用于输出警报信号的报警装置212、用于为输液系统输出电能的电源装置213，输入装置209、显示装置210、散热装置211、报警装置212、电源装置213分别与主控系统214连接。
可见，本实施例的输液输血设备200还包括输入装置209及显示装置 210，输入装置209负责设定具体的输注参数，显示装置210负责显示参数，工作状态及报警信息等，多采用LED数码管和液晶显示屏。当然，本实施例的显示参数包含但不限于设定的温度值，液体的实时温度值，加热时间、压力值等，均能够在设备上的显示装置210上显示，并能够被用户方便获取。
可见，因高频电源205会发出大量的热量，需要可靠的散热，本实施例的输液输血设备200还包括散热装置211，同时对高频电源205进行散热，以保证其正常工作。作为优选，散热装置211可以是散热风扇等具备散热能力的散热装置211，从而对高频电源205进行循环通风散热。
可见，为了保证用户能够及时的注意到报警信息，本实施例的输液输血设备200还包括报警装置212，可以发出警报，包括声音、图像或者灯光等或者两者组合的方式进行报警。
可见，本实施例的输液输血设备200还包括电源装置213，为整个系统提供能源，用于电源和内部电池供电的自动切换、电源分配管理、内部电池充放电管理等。
在本实施例中，与设备配套使用的耗材10主要包括具有药液或血液流经的输液管路13以及与输液管路13连通的被加热腔11、可见，和上述设备配套使用的耗材结构10主要包括具有药液或血液流经的输液管路13以及被加热腔11，被加热腔11具有一定的形状或结构，其被置于加热仓207中，流经被加热腔11的药液或血液可以被高频交变电场加热。
在本实施实例中，耗材10具有过滤器12，能够过滤掉输注液体内的异物。例如，当进行穿刺时，穿刺针可能会带下一些橡皮屑等异物，该异物由过滤器12过滤掉。
其中，如图5所示，被加热腔11可以是具有弯曲或螺旋状的管路形状，如弯曲的管路形状结构11a和螺旋状的管路形状结构11b，可见，为了增加被加热腔11的容积，被加热腔11可以是具有弯曲或螺旋状的管路形状。
同时，如图6所示，被加热腔11也可以是具有较大容积的腔体(相对于耗材管路)，如扁平的圆形结构11c。可见，因高频交变电场加热的原理，其腔体的结构也不需要被规定为特定的形状。主要满足药液或血液输送的要求即可。
一种可均匀加温的输液输血系统的应用方法实施例：
本发明提供的一种可均匀加温的输液输血系统的应用方法，输液输血系统是采用上述的输液输血系统，方法包括以下步骤：
方法包括以下步骤：将耗材结构10与可均匀加温的输液输血设备200进行连接，并通过蠕动泵208将预备的输注液体充满输液管路13；通过输入装置设定好输注参数，并启动设备进行高频交变电场加热，由主控系统214输出控制信号，以控制高频电场加热生装置产生高频交变电场来均匀加热需要加热的液体；当确定耗材结构10连接完毕后，启动输注。
在输注过程中，通过高频电源205以一定的频率工作，可以在第一电极板215及第二电极板216之间产生高频交变电场，对流入加热仓207内的输注液体进行加热。
在输注过程中，通过温度传感器203实时监测被加热液体的温度，当其达到预设值时，设备停止加热。
在输注过程中，在输注过程中，通过压力传感器202实时监测输液管路13内液体的压力；在输注过程中，通过气泡传感器201实时监测输液管路13内的气泡大小或者累积气泡容量。
在实际应用中，首先，将耗材结构10与可加温的输液输血设备200进行连接，准备好输注药液或血液，并通过蠕动泵208将药液或血液充满输液管路13。
接着，通过输入装置209设定好输注时的参数，如药液或血液的加温温度、输注的流速、输注药液或血液的最大压力等，并启动设备加热。
然后，将耗材结构10同患者1进行连接，并启动输注。
由此可见，本发明提供了一种可均匀加温的输液输血设备200及系统， 其具有加热仓207，加热仓207内设有第一电极板215、第二电极板216以及高频电源205，第一电极板215和第二电极板216平行放置并与高频电源205两端连接，当高频电源205工作时，在第一电极板215及第二电极板216之间会产生高频交变电场，流经耗材的药液或血液会被高频交变电场均匀加热。
其中，加热仓207中的极性分子(例如药液或血液中的水分子)具有固有偶极矩。在无外电场时，极性分子混乱排列，固有偶极矩矢量各方向的分布几率相等，所有分子固有偶极矩的矢量和为零，整个介质仍保持电中性；但在外电场作用下，每个极性分子在电场中都受到转动力矩的作用而产生旋转，并且有沿电场方向排布的趋向，产生取向极化(或偶极极化)的现象。极性分子在此过程中高速震动摩擦而产生热能，温度升高。
同时，输液设备还具有至少一处温度传感器203，可以对被加热的药液或血液温度进行实时监测。
同时，该设备配套使用用于输送药液或血液的管路或者容器耗材一般由高分子材料构成，如医用PVC材料，属于非极性分子，它们则极少吸收高频交变电场的能量，在加热仓207中，不会或极少被加热。
需要说明的是，以上仅为本发明的优选实施例，但发明的设计构思并不局限于此，凡利用此构思对本发明做出的非实质性修改，也均落入本发明的保护范围之内。

Claims (13)

  1. 一种可均匀加温的输液输血设备，其特征在于，包括：
    主控系统、加热仓、至少一个高频电源、高频电场加热装置，所述主控系统与所述高频电源电连接，所述高频电源的输出端与所述高频电场加热装置连接，所述高频电场加热装置放置于所述加热仓内，由所述主控系统输出控制信号，以控制所述高频电场加热生装置产生高频交变电场来均匀加热需要加热的液体；
    所述输液输血设备还包括温度传感单元，所述温度传感单元与所述主控系统连接，用于检测温度传感信号。
  2. 根据权利要求1所述的输液输血设备，其特征在于：
    所述高频电场加热装置包括相对配置的第一电极板以及第二电极板，所述高频电源的两个输出端分别与所述第一电极板以及第二电极板连接，所述高频电源的输出端向所述第一电极板、第二电极板之间施加高频电压，在所述第一电极板、第二电极板之间产生高频交变电场。
  3. 根据权利要求2所述的输液输血设备，其特征在于：
    所述第一电极板、第二电极板在垂直于电场的投影方向上具有相同或近似相同的面积与形状。
  4. 根据权利要求3所述的输液输血设备，其特征在于：
    所述第一电极板与第二电极板在产生高频交变电场的两个相邻面为平面，且相互平行放置。
  5. 根据权利要求4所述的输液输血设备，其特征在于：
    所述第一电极板、第二电极板为相互平行放置的圆形或方形金属平板电极。
  6. 根据权利要求4所述的输液输血设备，其特征在于：
    所述第一电极板、第二电极板为多组间隔平行放置的结构；
  7. 根据权利要求2所述的输液输血设备，其特征在于：
    所述第一电极板、第二电极板为由内至外分布的同心环形电极组合。
  8. 根据权利要求2至6任一项所述的输液输血设备，其特征在于：
    所述第一电极板、第二电极板与所述加热仓之间设有绝缘结构。
  9. 一种可均匀加温的输液输血系统，其特征在于，包括：
    如权利要求1至8任一项所述的可均匀加温的输液输血设备，所述输液输血设备包括主控系统、加热仓、至少一个高频电源、高频电场加热装置，所述主控系统与所述高频电源电连接，所述高频电源的输出端与所述高频电场加热装置连接，所述高频电场加热装置放置于所述加热仓内，由所述主控系统输出均匀加热信号，以控制所述高频电场加热生装置产生高频交变电场来加热需要加热的液体；所述输液输血设备还包括温度传感单元，所述温度传感单元与所述主控系统连接，用于检测温度传感信号；
    与所述输液输血设备配合使用的耗材结构，所述耗材结构为高分子材料构成，其包括与输液管路以及与输液管路连通的被加热腔，所述被加热腔放置于所述加热仓内。
  10. 根据权利要求9所述的输液输血系统，其特征在于：
    所述输液输血设备还包括用于对输液管路内液体进行挤压的蠕动泵，所述蠕动泵由所述主控系统控制输出，所述蠕动泵的输出端通过输液管路连接至所述传感单元的气泡传感器。
  11. 根据权利要求10所述的输液输血系统，其特征在于：
    所述传感单元包括压力传感器、所述气泡传感器以及所述温度传感器，所述压力传感器用于检测输液管路内的液体压力，并发送第一传感信号至所述主控系统；所述气泡传感器检测输液管路内的液体中的气泡大小或者累积气泡容量，并发送第二传感信号至所述主控系统；所述温 度传感器用于检测所述被加热腔内液体的温度，并发送第三传感信号至所述主控系统。
  12. 根据权利要求9所述的输液输血系统，其特征在于：
    所述输液输血设备还包括输入装置、显示装置、散热装置、报警装置、电源装置，所述输入装置、显示装置、散热装置、报警装置、电源装置分别与所述主控系统连接。
  13. 一种可均匀加温的输液输血系统的应用方法，其特征在于，所述输液输血系统是采用上述权利要求9至12任一项所述的输液输血系统，所述方法包括以下步骤：
    将耗材结构与可均匀加温的输液输血设备进行连接，并通过蠕动泵将预备的输注液体充满输液管路；
    通过输入装置设定好输注参数，并启动设备进行高频交变电场加热，由主控系统输出控制信号，以控制高频电场加热生装置产生高频交变电场来均匀加热需要加热的液体；
    当确定耗材结构连接完毕后，启动输注。
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