WO2022255602A1

WO2022255602A1 - Microstructure film for preventing diffusion of infectious disease

Info

Publication number: WO2022255602A1
Application number: PCT/KR2022/003414
Authority: WO
Inventors: 조영태; 김석; 김우영
Original assignee: 창원대학교 산학협력단
Priority date: 2021-06-04
Filing date: 2022-03-11
Publication date: 2022-12-08
Also published as: KR102388734B1

Abstract

The present invention relates to a microstructure film for preventing diffusion of infectious diseases, which can decrease contagious infection by effectively capturing particles contained in liquid drops. The present invention includes a film on the surface of which a micropattern structure having septa is formed, wherein when liquid drops containing particles therein are smeared on the surface and vaporize, the particles are captured within the septa or the cavity between the septa and adhere to the surface while moving along the liquid drop line, which is the boundary between the liquid drops and air.

Description

Microstructured film to prevent the spread of infectious diseases

The present invention relates to a microstructured film for preventing the spread of infectious diseases, and more particularly, to a film capable of reducing infection by contact by effectively trapping particles contained in droplets.

Due to the recent COVID-19 epidemic, it is sensitive to viral infections transmitted through human droplets. In particular, when a virus is stained on a medium that humans frequently contact, such as an elevator, a bus handle, or a doorknob, the virus can survive for a certain period of time, so it is easy to be infected with the virus when coming into contact with the medium.

Currently, in order to prevent the above-mentioned problems, antiviral films deposited with copper (Cu) are applied to daily life as a technology to effectively block infection by contact with contaminated objects, but viruses on the surface of the film are minimal. It takes 4 hours to die, so there is still a risk of infection if humans come in contact with it before that time. Therefore, it is necessary to develop a film for effectively blocking infection by contact.

An object of the present invention is to solve the above-mentioned problems of the conventional film, and to provide a new type of invention capable of effectively trapping particles by forming a fine pattern structure with barrier ribs in the film.

In order to achieve the above object, the microstructured film for preventing the spread of infectious diseases according to the present invention includes a film having a fine pattern structure having barrier ribs formed on the surface, and when liquid droplets containing particles are buried on the surface and evaporated , The particles are characterized in that while moving along the droplet line, which is the boundary between the droplet and the air, they are captured in the partition wall or the cavity, which is the space between the partition walls, and adhere to the surface.

According to one embodiment, the angle between the barrier rib and the surface is characterized in that 90 °.

In addition, according to another embodiment, the barrier rib is characterized in that the hexagonal barrier rib.

In addition, according to another embodiment, the barrier rib is characterized in that formed inclined at a predetermined angle.

In addition, according to another embodiment, the barrier rib is characterized in that the inverted pyramid-shaped barrier rib.

Here, the space portion is characterized in that it is formed in a 'V' shape.

Meanwhile, according to one embodiment, the film is composed of a hydrophilic material, and when the droplet evaporates, the droplet line is formed concavely.

Here, when the droplet evaporates, a contact radius with the surface is fixed.

Meanwhile, according to another embodiment, the film is composed of a hydrophobic material, and when the droplet evaporates, the droplet line is formed convexly.

Here, it is characterized in that the droplet is slipped when it evaporates.

In addition, here, when the slipping is performed, the contact angle of the droplet is characterized in that it is maintained constant.

Further, here, when the droplet evaporates, the particles are characterized in that they are aggregated in the lower region of the cavity.

According to the present invention, the degree of trapping foreign particles, for example, particles having an infectious substance, etc. is excellent in the micropattern structure having barrier ribs, so infection by contact can be significantly reduced.

In addition, according to the present invention, it can be seen that the particle collection efficiency of the film having the inverted pyramidal partition structure is superior to that of the planar film.

In addition, according to the present invention, when the film is made of a hydrophobic material rather than a hydrophilic material, it can be seen that the particle collection efficiency is excellent due to the slipping effect.

1 is a view showing a state in which a micropattern structure having hexagonal barrier ribs is formed on the surface of a microstructured film for preventing the spread of infectious diseases according to an embodiment of the present invention.

2 is a view showing a state in which a micropattern structure having an inverted pyramidal partition is formed on the surface of a microstructured film for preventing the spread of infectious diseases according to an embodiment of the present invention.

3 is a view showing a spraying test apparatus according to an embodiment of the present invention.

4 is a view showing a state in which droplets are in contact with the surface of a film composed of a hydrophilic material.

5 is a view showing a state in which liquid droplets contact a surface of a film formed of a hydrophilic material and having a hexagonal barrier rib with a fine pattern structure formed thereon.

6 is a view showing a state in which liquid droplets are in contact with the surface of a film formed of a hydrophilic material and having a fine pattern structure having an inverted pyramidal barrier rib.

7 is a view showing a state in which droplets are in contact with the surface of a film composed of a hydrophobic material.

8 is a view showing a process of slipping while evaporating droplets on the surface of a film composed of a hydrophobic material.

9 is a view showing a state in which liquid droplets are in contact with the surface of a film formed of a hydrophobic material and having a hexagonal barrier rib with a fine pattern structure formed thereon.

10 is a view showing a state in which liquid droplets contact a surface of a film formed of a hydrophobic material and having a fine pattern structure having an inverted pyramidal barrier rib.

11 is a graph showing the change in the contact diameter of droplets during evaporation.

12 is a particle state observed by spraying droplets on the surface of a film composed of a hydrophilic material, FIG. 12 (a) is a view showing the adhesion state of the sprayed droplets on the film surface, and c) is a diagram showing a state in which particles are captured, and FIG. 12(d) is a diagram illustrating the principle of particle capture.

13 is a particle state observed by spraying droplets on the surface of a film composed of a hydrophobic material, FIG. 13(a) is a view showing the adhesion state of the sprayed droplets on the film surface, and c) is a diagram showing a state in which particles are captured, and FIG. 13(d) is a diagram illustrating the principle of capturing particles.

Figure 14 relates to the particle collection efficiency of the film surface on which the fine pattern structure is formed, Figure 14 (a) is a graph showing the number of particles transferred to the outside from the film surface, Figure 14 (b) is a graph of the film surface It is a graph showing particle collection efficiency.

15 is a view showing a state in which adenovirus particles are captured on the surface of a film composed of hydrophilic and hydrophobic materials, respectively.

Hereinafter, a microstructured film for preventing the spread of infectious diseases according to an embodiment of the present invention according to a preferred embodiment will be described in detail with reference to the accompanying drawings. Here, the same reference numerals are used for the same components, and repeated descriptions and detailed descriptions of known functions and configurations that may unnecessarily obscure the subject matter of the invention are omitted. Embodiments of the invention are provided to more completely explain the present invention to those skilled in the art. Accordingly, the shapes and sizes of elements in the drawings may be exaggerated for clarity.

If droplets generated during breathing or droplets suspended in the air contain particles (for example, particles of pathogens such as viruses, etc., or any particle that may be a source of contamination), any part of the body may come into contact with the object that these droplets or droplets come into contact with. Contact can expose you to contaminants. The present applicant has found that contact infection can be minimized by directly performing an experiment on foreign particle collection by droplets or liquid droplets using a film having a fine pattern structure.

1 is a view showing a state in which a micropattern structure having a hexagonal barrier rib is formed on the surface of a microstructured film for preventing the spread of infectious diseases according to an embodiment of the present invention, and FIG. It is a diagram showing a state in which a micropattern structure having an inverted pyramidal partition is formed on the surface of a microstructured film for preventing disease spread. 1 and 2 show a state in which the surface of the film is slightly obliquely viewed from above.

As shown in FIGS. 1 and 2, the present applicant provides external externalities for the case where the fine pattern structure having hexagonal barrier ribs is formed on the surface of the film and the case where the fine pattern structure having inverted pyramidal barrier ribs is formed on the surface of the film. Particle collection experiments were performed. This is because the mechanical robustness of the microstructure of the barrier rib pattern and the particle collecting performance were considered. However, the fine pattern structure may be formed in various ways.

Referring to FIGS. 1 and 2 , a cavity C is formed inside the hexagonal or inverted pyramidal partition wall W. In one embodiment of the present invention, the length of the barrier rib and the size of the cavity are on the order of several microns.

In one embodiment of the present invention, the hexagonal or inverted pyramidal barrier rib pattern structure was manufactured by a UV-NIL (Ultraviolet-Nano-imprinting-Lithography) process.

In one embodiment of the present invention, the angle α between the hexagonal partition wall W and the surface is 90° (see FIG. 5), and the angle α between the inverted pyramidal partition wall W is 125° (see FIG. 6). . As will be described later, the angle α of the barrier rib W suggests a direction in which the particles can move. However, the angle α of the barrier rib W may be variously set.

On the other hand, the film according to an embodiment of the present invention may be composed of a hydrophilic or hydrophobic material. Accordingly, the present applicant prepared films composed of hydrophilic or hydrophobic materials, respectively, and conducted an experiment to compare the collection efficiency of particles included in droplets.

As shown in Figure 3, according to the spraying test apparatus according to an embodiment of the present invention, a spray nozzle capable of spraying droplets or droplets (hereinafter referred to as droplets) containing particles, and a size of 2 x 2cm ² of test surfaces (surfaces shown in Fig. 1 or Fig. 2) are installed at intervals of approximately 20 cm or less. However, the size of the spray nozzle and the test surface may be set in various ways according to the experimental conditions. The droplets sprayed from the spray nozzle evaporate after a certain period of time after contacting the test surface. At this time, the droplet evaporation process and particle migration process in the film composed of hydrophilic and hydrophobic materials are observed.

4 is a view showing a state in which droplets are in contact with the surface of a film made of a hydrophilic material, and FIG. 5 is a view showing a state in which a droplet is in contact with a surface of a film formed of a hydrophilic material and having a fine pattern structure having hexagonal barrier ribs, 6 is a view showing a state in which liquid droplets are in contact with the surface of a film formed of a hydrophilic material and having a fine pattern structure having an inverted pyramidal barrier rib.

4 to 6, the film is composed of a hydrophilic material.

4 shows a state in which droplets are in contact with a planar film surface. Particles P are included in the droplets. A droplet line L is formed at the boundary between the droplet and the air, and the droplet line L changes as the droplet evaporates. When the film is made of a hydrophilic material, the contact force (pinning) between the film surface and the droplet is large, so when the droplet evaporates and the droplet line (L) decreases (when it descends), the contact line (the line where the droplet and the film surface meet) is fixed. can Alternatively, it may be considered that the contact radius of the droplet is fixed. This is referred to as a stick mode (CCR) in this specification. Meanwhile, even in the process of evaporating the droplets, the particles P are continuously trapped on the surface of the film by the droplets.

Referring to FIG. 5 , a droplet line L is concavely formed along the shape of the cavity C in a droplet contacting the surface of a film having a fine pattern structure with hexagonal barrier ribs. While the droplet is evaporating, the droplet line (L) is reduced while maintaining a concave state. At this time. Since the film is composed of a hydrophilic material, the particles (P) captured in the droplet are evenly adhered to the film surface along the droplet line (L).

Referring to FIG. 6 , when a droplet contacts the surface of a film having a fine pattern structure having an inverted pyramidal barrier rib, a droplet line L is concave along the shape of the cavity C. Here, the cavity (C) is formed in a substantially 'V' shape. While the droplet is evaporating, the droplet line (L) is reduced while maintaining a concave state. At this time, since the film is composed of a hydrophilic material, the particles (P) captured in the droplet are evenly adhered to the film surface along the droplet line (L).

7 is a view showing a state in which droplets are in contact with the surface of a film composed of a hydrophobic material, FIG. 8 is a diagram showing a process in which droplets are slipped while evaporating on the surface of a film composed of a hydrophobic material, and FIG. 10 is a view showing a state in which droplets are in contact with the surface of a film on which a fine pattern structure having hexagonal barrier ribs is formed and formed of a hydrophobic material, and FIG. It is a diagram showing a state.

7 to 10, the film is composed of a hydrophobic (water repellent) material.

7 shows a state in which droplets contact the surface of a planar film. Particles P are included in the droplets. A droplet line L is formed at the boundary between the droplet and the air, and the droplet line L changes as the droplet evaporates. As shown in FIG. 8 , when the film is made of a hydrophobic material, the droplet contacts the film surface while forming a constant contact angle θ. Looking at the process of evaporation of the droplet, the contact line decreases over time, but the contact angle remains constant. This is referred to as a sleep mode (CCA) in this specification. A detailed droplet evaporation process will be described later. Meanwhile, even in the process of evaporating the droplets, the particles P are continuously captured on the surface of the film by the droplets.

Referring to FIG. 9 , a droplet line (L) is convexly formed along the shape of the cavity (C) of a droplet contacting the surface of a film having a fine pattern structure with hexagonal barrier ribs. While the droplet is evaporating, the droplet line (L) is reduced while maintaining a convex state. At this time, since the film is composed of a hydrophobic material, the particles (P) captured in the droplet are adhered to the lower portion of the cavity (C) of the film along the droplet line (L).

Referring to FIG. 10 , a droplet line (L) is convexly formed along the shape of the hollow portion (C) of a droplet contacting the surface of a film having a fine pattern structure having an inverted pyramidal barrier rib. Here, the cavity (C) is formed in a substantially 'V' shape. While the droplet is evaporating, the droplet line (L) is reduced while maintaining a convex state. At this time, since the film is composed of a hydrophobic material, the particles (P) trapped in the droplet are aggregated and adhered to each other at the lower portion of the cavity (C) of the film along the droplet line (L).

Looking back at the foregoing, it can be seen that the particles P are adhered to a limited area of the film in an aggregated state when the film is made of a hydrophobic material rather than when the film is made of a hydrophilic material.

Referring to FIG. 11, it can be observed that droplets on the surface of the hydrophilic film evaporate with a constant contact radius (CCR mode), and on the surface of the hydrophobic film, droplets initially evaporate with a constant contact radius (CCR mode), then From this point on, it can be observed that the contact radius decreases while maintaining a constant contact angle (CCA mode).

On the other hand, as shown in FIG. 11, it can be seen that traces of ring patterns are formed when droplets evaporate on the surface of the hydrophilic or hydrophobic film.

As shown in (a) of FIG. 12 , droplets sprayed on the surface of a film composed of a hydrophilic material tended to merge with each other. In addition, as shown in (b) to (d) of FIG. 12, it can be confirmed that the particles P are evenly adhered to the film surface along the concave droplet line L.

As shown in (a) of FIG. 13 , droplets sprayed on the film surface composed of a hydrophobic material maintained small fine droplets. In addition, as shown in (b) to (d) of FIG. 13, it can be confirmed that most of the particles P are aggregated with each other and adhered to the lower region of the cavity C along the convex droplet line L. can At this time, the particles are aggregated at the corners created by the barrier rib (W) and the surface of the lower area of the cavity (C) by the evaporated droplets (in the case of the hexagonal barrier rib pattern structure), or at the connection portion between the barrier ribs (W). It can be aggregated (in the case of an inverted pyramidal partition wall pattern structure).

Comparing FIGS. 12 and 13 , it can be seen that the particle collection efficiency of the film made of a hydrophobic material is superior to that of the film made of a hydrophilic material. As described above, this is because the contact radius is not fixed when the droplets contact on the surface of the film composed of the hydrophobic material, and the droplets evaporate due to the slip mode and the particles aggregate with each other.

In FIG. 14 , a tape peeling test was performed to confirm the particle collection efficiency of the surface of the film on which the fine pattern structure was formed. After spraying droplets containing particles on the film surface, pixels on each surface were counted before and after peeling. In (a) and (b) of FIG. 14, films having a planar structure, a hexagonal barrier structure, and an inverted pyramidal barrier structure were prepared with hydrophilic and hydrophobic materials, respectively, and then peeling tests were performed. Results appear. As shown in (a) and (b) of FIG. 14 , it can be seen that the particle collection efficiency is excellent on the surface of the film having the barrier rib structure compared to each planar structure. In addition, the particle collection efficiency is slightly better in the inverted pyramidal barrier rib structure than in the hexagonal barrier rib structure.

In the above-described FIGS. 12 and 13, the degree of particle capture was tested using inorganic particles, but in FIG. 15, the degree of particle capture was tested using pathogenic particles such as viruses.

An inverted pyramidal barrier rib structure is formed on the surface of the film. 15(a) shows a case where the film is made of a hydrophilic material, and (b) of FIG. 15 shows a case where the film is made of a hydrophobic material. As shown in FIG. 15, it can be seen that biological nanoparticles are aggregated on the surface of the micropattern structure, which is consistent with the results of the experiment using the inorganic particles described above.

As described above, the film formed with the micropatterned structure having barrier ribs according to an embodiment of the present invention has an excellent degree of capturing particles having an infectious substance, and thus infection by contact can be significantly reduced.

Meanwhile, according to one embodiment of the present invention, it is possible to manufacture the film transparently, and it can be used for objects that people frequently contact, such as elevator buttons, smart phones, and touch screens.

The present invention has been described with reference to an embodiment shown in the accompanying drawings, but this is only exemplary, and those skilled in the art will understand that various modifications and equivalent other embodiments are possible therefrom. You will be able to. Therefore, the true protection scope of the present invention should be defined only by the appended claims.

Claims

A film having a fine pattern structure having barrier ribs formed thereon;

When a droplet containing particles is buried on the surface and evaporates, the particles move along the droplet line, which is the boundary between the droplet and the air, and are trapped in the partition wall or the cavity between the partition walls and adhered to the surface. A microstructured film for preventing the spread of infectious diseases.
According to claim 1,

The microstructured film for preventing the spread of infectious diseases, characterized in that the angle between the barrier and the surface is 90 °.
According to claim 1,

The barrier rib is a microstructured film for preventing the spread of infectious diseases, characterized in that the hexagonal barrier rib.
According to claim 1,

The barrier rib is a microstructured film for preventing the spread of infectious diseases, characterized in that formed inclined at a predetermined angle.
According to claim 1,

The barrier rib is a fine structured film for preventing the spread of infectious diseases, characterized in that the inverted pyramid-shaped barrier rib.
According to claim 5,

The microstructured film for preventing the spread of infectious diseases, characterized in that the cavity is formed in a 'V' shape.
According to claim 1,

The film is composed of a hydrophilic material, and when the droplet evaporates, the droplet line is formed concavely.
According to claim 7,

A microstructured film for preventing the spread of infectious diseases, characterized in that the contact radius with the surface is fixed when the droplet evaporates.
According to claim 1,

The film is composed of a hydrophobic material, and when the droplet evaporates, the droplet line is formed convexly.
According to claim 9,

A microstructured film for preventing the spread of infectious diseases, characterized in that slipping occurs when the droplets evaporate.
According to claim 10,

A microstructured film for preventing the spread of infectious diseases, characterized in that the contact angle of the droplet is kept constant when the slipping is performed.
According to claim 9,

The microstructured film for preventing the spread of infectious diseases, characterized in that when the droplets evaporate, the particles aggregate in the lower region of the cavity.