WO2022175991A1 - Food supplement for a nutri-cosmetic treatment of alopecia and for cardiovascular prevention - Google Patents

Food supplement for a nutri-cosmetic treatment of alopecia and for cardiovascular prevention Download PDF

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Publication number
WO2022175991A1
WO2022175991A1 PCT/IT2021/050319 IT2021050319W WO2022175991A1 WO 2022175991 A1 WO2022175991 A1 WO 2022175991A1 IT 2021050319 W IT2021050319 W IT 2021050319W WO 2022175991 A1 WO2022175991 A1 WO 2022175991A1
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Prior art keywords
alopecia
hair
food supplement
nutri
melannurca
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PCT/IT2021/050319
Other languages
French (fr)
Inventor
Cristiano REFI
Daniele VERDEMARE
Jessica SIMONI
Original Assignee
Genes S.R.L.
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Priority to BR112023016156A priority Critical patent/BR112023016156A2/en
Publication of WO2022175991A1 publication Critical patent/WO2022175991A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A23L29/35—Degradation products of starch, e.g. hydrolysates, dextrins; Enzymatically modified starches
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L31/00—Edible extracts or preparations of fungi; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration

Definitions

  • the present invention is part of the technological sector of food supplements.
  • it refers to a food supplement for the nutritious treatment of alopecia and cardiovascular prevention, with positive effects on the general vitality of the organism.
  • Food supplements are foods presented in small consumption units such as capsules, tablets, ampoules and the like. They are characterized as concentrated sources of nutrients or other substances with a "physiological" effect that do not have a purpose of treatment, the exclusive prerogative of drugs, because they are designed and proposed to favor the regular performance of specific functions or the normality of specific parameters in the body, functional or to reduce disease risk factors.
  • - aggressive hair treatments such as hair dyeing, curling, perming
  • diseases such as anemia, psoriasis, vitiligo, alopecia, seborrheic dermatitis
  • hormonal dysfunctions such as thyroid disease, polycystic ovary syndrome, diabetes
  • incorrect nutrition due to drastic slimming diets deficiency of vitamin D, iron, copper and zinc
  • drug therapies such as drugs to reduce cholesterol, steroids, diuretics, chemotherapy
  • Hair loss mainly affects men (about 60%). Generally it begins very slowly, sometimes associated with the increase in sebum production and the presence of dandruff, and it is much earlier and more severe the more family members are affected.
  • the main cause of hair loss in men is androgenetic alopecia (or common baldness) so called because it is mainly caused by two factors, namely androgen hormones and heredity.
  • This type of alopecia does not depend on an excess of androgens, but on a greater sensitivity of the hair to them. Men suffering from baldness, in fact, do not have higher levels of androgens in the blood than their peers with hair, but they are simply more sensitive to the effects that these hormones cause at the level of the hair follicle.
  • Hair loss is less common in women than in men. Usually, female hair is thicker, more resistant and shows faster and more prolonged growth than male hair. In women, the main cause of hair loss is to be found in hormonal imbalances. Menopause, for example, represents a very important and delicate phase. During this period of life, some morphological changes are often observed in the hair that tends to thin and thin out moderately. After menopause, 50% of women in fact present a thinning of their hair.
  • telogen effluvium which affects the entire scalp and which, in the initial stages, may be imperceptible.
  • diffuse loss also called telogen effluvium
  • hair loss follows a different dynamic than in men: it is later, has a slower evolution and first affects the top of the head and then the other areas of the scalp.
  • a form of hair loss that can be found with equal frequency in both men and women is alopecia areata, so called because hair loss causes the formation of bald areas of various sizes in a short time. It often begins before maturity and can manifest itself in any part of the scalp, as well as in the armpits and pubis; in men it can also occur on the beard.
  • alopecia areata In most cases, the hair that falls out due to alopecia areata grows back spontaneously, but the disease can recur. It is mainly found in young adults, while it is rare above the age of 60. As for the causes, alopecia areata is now considered with certainty an autoimmune-based disease with a complex component of genetic transmission on which other factors also intervene such as psychophysical stress, incorrect nutrition or the presence of diseases, especially those on an autoimmune basis.
  • a woman in particular, needs: - vitamin B12;
  • Natural hair supplements contain full-action ingredients that work from the scalp to the tips. Mainly they are based on:
  • - mineral salts magnesium, which promotes blood circulation, iron which feeds the hemoglobin responsible for the distribution of oxygen in the various tissues, zinc which constitutes 95% of the hair structure; vitamins E, C: restructure the hair and strengthen it, making it shiny and healthy-looking;
  • - antioxidants counteract hair loss and aging
  • amino acids essential for proteins that help hair growth and responsible for the health of the hair bulb.
  • the supplements must be taken for a period ranging between two and three months and the treatment must be associated with a correct diet, as the problem of hair loss together with brittle nails can reflect a lack of certain vitamins, in the body, not metabolized by the diet.
  • Object of the present invention is providing a food supplement, with new ingredients, which has a particular positive effect in the body, mainly in the nutritious treatment of alopecia, but also in cardiovascular prevention and with a significant general beneficial action on organism, with a significant increase in effectiveness compared to current supplements.
  • composition according to the invention is a food supplement for the nutri-cosmetic treatment of alopecia, with beneficial effects in cardiovascular prevention and on the body.
  • This supplement is made from 100% natural products and is characterized by having the following composition:
  • the melannurca extract is preferably obtained from a variety of PGI Annurche apples originating in the countryside of Pozzuoli (NA), and Ganoderma lucidum is a mushroom widely used in traditional Chinese medicine.
  • the formulation in question can also be used as an adjuvant for hair protection and maintenance of the general state of well-being.
  • the food supplement for hair care according to the invention is composed of 100% natural ingredients, based on dry apple extract of melannurca and dry extract of Ganoderma lucidum, a mushroom widely used in traditional Chinese medicine, to which Numerous therapeutic properties and the ability to cure a wide variety of ailments are attributed.
  • the food supplement according to the invention has the following composition:
  • the commercial form is preferably a 10ml stick pack.
  • Melannurca is a fruit that contains a high amount of polyphenols, especially type B procyanidins, responsible for positive health effects.
  • Melannurca extract has given excellent results in the nutri-cosmetic treatment of alopecia, thanks to the abundant amount of procyanidin B2, this active ingredient, in fact, has the ability to stimulate hair regrowth and trophism both in vitro and in vivo, promotes the anagen phase of the life cycle, increases the biosynthesis of keratin and stimulates the stem cells of the outer root sheath, favoring the reorganization of the follicle.
  • Ganoderma lucidum or Reishi is a mushroom that contains a complex of active ingredients capable of developing some positive effects in favor of the body and the human organism.
  • Reishi contains over 150 active substances with a beneficial effect that support its validity as a natural remedy capable of covering multiple functions, each of which attributable to every single active ingredient contained in it: polysaccharides, oleic acid, ganoderic and pantothenic acid, nucletodes, ergosterols, proteins and peptides. It also has traces of essential micronutrients such as iron, manganese, copper, potassium, calcium and germanium, as well as B vitamins, amino acids, glucose, adenosine, mannose. Alopecia areata is an autoimmune disease that causes patchy hair loss.
  • the nutraceutical supplement according to the invention is therefore a 100% natural food supplement, which can be administered orally, in semi-solid pharmaceutical form (gel), produced in single pre-dosed sachets whose formulation is mainly composed of two natural extracts such as: dry extract of melannurca and ganoderma extract in variable percentages depending on the presence of excipients or any additional active ingredients present in minority compositions.
  • gel semi-solid pharmaceutical form
  • the melannurca extract (both alone and associated with other components such as zinc and selenium) after 60 days of treatment increases the density, size and keratin content of the hair.
  • Ganoderma lucidum has shown exceptional results in hair regrowth; the constant use of food supplements containing standardized Reishi extract would seem to act on alopecia by counteracting the conversion of the hormone testosterone into dihydrotestosterone (DHT), the latter responsible for androgenetic alopecia (AGA).
  • DHT dihydrotestosterone
  • AGA androgenetic alopecia
  • the melannurca extract restores the health and balance of both the skin (scalp) and the hair, amplifying the regrowth action of the Ganoderma lucidum extract.
  • the formulation according to the invention therefore guarantees fast and long-lasting regrowth, giving the hair all the nutrients necessary for its development and fortification.

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Abstract

The present invention is part of the technological sector of food supplements. In particular, it refers to a food supplement for the nutritious treatment of alopecia and cardiovascular prevention, with positive effects on the general vitality of the organism, and is characterized by having the following composition: dry extract of melannurca 0,8 g dry extract of Ganoderma lucidum 1 g soluble dietary fiber (maltodextrin) 7.2 g

Description

FOOD SUPPLEMENT FOR A NUTRI-COSMETIC TREATMENT OF
ALOPECIA AND FOR CARDIOVASCULAR PREVENTION
The present invention is part of the technological sector of food supplements. In particular, it refers to a food supplement for the nutritious treatment of alopecia and cardiovascular prevention, with positive effects on the general vitality of the organism.
Food supplements are foods presented in small consumption units such as capsules, tablets, ampoules and the like. They are characterized as concentrated sources of nutrients or other substances with a "physiological" effect that do not have a purpose of treatment, the exclusive prerogative of drugs, because they are designed and proposed to favor the regular performance of specific functions or the normality of specific parameters in the body, functional or to reduce disease risk factors.
One area in which food supplements can have a beneficial effect is in the nutri-cosmetic treatment of alopecia, in cardiovascular prevention and action in the general vitality of the organism. In particular, as regards alopecia, the loss during the day of a certain number of hairs (50 ÷ 100) is a completely natural event. In some conditions, however, this phenomenon can increase until it leads to a progressive thinning of the hair.
There are numerous causes that can lead to hair loss, for example: - aggressive hair treatments such as hair dyeing, curling, perming; the presence of diseases such as anemia, psoriasis, vitiligo, alopecia, seborrheic dermatitis; - hormonal dysfunctions such as thyroid disease, polycystic ovary syndrome, diabetes; incorrect nutrition due to drastic slimming diets, deficiency of vitamin D, iron, copper and zinc; - drug therapies such as drugs to reduce cholesterol, steroids, diuretics, chemotherapy;
- psychophysical stress;
- genetic predisposition.
Hair loss mainly affects men (about 60%). Generally it begins very slowly, sometimes associated with the increase in sebum production and the presence of dandruff, and it is much earlier and more severe the more family members are affected. The main cause of hair loss in men is androgenetic alopecia (or common baldness) so called because it is mainly caused by two factors, namely androgen hormones and heredity.
This type of alopecia does not depend on an excess of androgens, but on a greater sensitivity of the hair to them. Men suffering from baldness, in fact, do not have higher levels of androgens in the blood than their peers with hair, but they are simply more sensitive to the effects that these hormones cause at the level of the hair follicle.
Hair loss is less common in women than in men. Usually, female hair is thicker, more resistant and shows faster and more prolonged growth than male hair. In women, the main cause of hair loss is to be found in hormonal imbalances. Menopause, for example, represents a very important and delicate phase. During this period of life, some morphological changes are often observed in the hair that tends to thin and thin out moderately. After menopause, 50% of women in fact present a thinning of their hair.
Among the forms of hair loss that mainly affect women, but which is also found in men, there is the so-called diffuse loss, also called telogen effluvium, which affects the entire scalp and which, in the initial stages, may be imperceptible. Generally it occurs after "important" episodes such as fever, childbirth or surgery, it lasts an average of 2 ÷ 3 months and, although recovery is slow, the scalp can return to normal.
In recent years, cases of female alopecia appearing to arise at an early age, probably due to psychophysical stress and other environmental causes that directly or indirectly affect hormonal balance.
In women, generally, hair loss follows a different dynamic than in men: it is later, has a slower evolution and first affects the top of the head and then the other areas of the scalp.
A form of hair loss that can be found with equal frequency in both men and women is alopecia areata, so called because hair loss causes the formation of bald areas of various sizes in a short time. It often begins before maturity and can manifest itself in any part of the scalp, as well as in the armpits and pubis; in men it can also occur on the beard.
In most cases, the hair that falls out due to alopecia areata grows back spontaneously, but the disease can recur. It is mainly found in young adults, while it is rare above the age of 60. As for the causes, alopecia areata is now considered with certainty an autoimmune-based disease with a complex component of genetic transmission on which other factors also intervene such as psychophysical stress, incorrect nutrition or the presence of diseases, especially those on an autoimmune basis.
The constant use of specific products can represent a valid support for combating hair loss.
The above causes are normally counteracted through the use of food supplements that provide the body with nutrients or other substances with a "physiological" effect. The use of supplements, in fact, makes all skin appendages, such as hair and nails, strong and healthy. To obtain this effect they must contain particular active ingredients such as:
- sulfur amino acids; vitamins; - minerals;
- biotin;
- pantothenic acid.
A woman, in particular, needs: - vitamin B12;
- folic acid; which are useful for preventing weakness linked to possible anemia.
Finally, there is the group of antioxidant vitamins.
Natural hair supplements contain full-action ingredients that work from the scalp to the tips. Mainly they are based on:
- mineral salts: magnesium, which promotes blood circulation, iron which feeds the hemoglobin responsible for the distribution of oxygen in the various tissues, zinc which constitutes 95% of the hair structure; vitamins E, C: restructure the hair and strengthen it, making it shiny and healthy-looking;
- antioxidants: counteract hair loss and aging; amino acids: essential for proteins that help hair growth and responsible for the health of the hair bulb.
Generally, the supplements must be taken for a period ranging between two and three months and the treatment must be associated with a correct diet, as the problem of hair loss together with brittle nails can reflect a lack of certain vitamins, in the body, not metabolized by the diet.
Object of the present invention is providing a food supplement, with new ingredients, which has a particular positive effect in the body, mainly in the nutritious treatment of alopecia, but also in cardiovascular prevention and with a significant general beneficial action on organism, with a significant increase in effectiveness compared to current supplements.
The above and other objects, as will be explained below, are achieved with a formulation according to claim 1.
The composition according to the invention is a food supplement for the nutri-cosmetic treatment of alopecia, with beneficial effects in cardiovascular prevention and on the body. This supplement is made from 100% natural products and is characterized by having the following composition:
- dry extract of melannurca 0,8 g
- dry extract of Ganoderma lucidum 1 g - soluble dietary fiber (maltodextrin) 7.2 g The melannurca extract is preferably obtained from a variety of PGI Annurche apples originating in the countryside of Pozzuoli (NA), and Ganoderma lucidum is a mushroom widely used in traditional Chinese medicine.
The formulation in question can also be used as an adjuvant for hair protection and maintenance of the general state of well-being.
It is understood that all the attached claims form an integral part of the present description.
It will be immediately obvious that innumerable variations and modifications (for example relating to nature, concentration and equivalent functionality) can be made to the described composition without departing from the scope of the invention, as appears from the attached claims.
The present invention will be better described by a preferred embodiment, given by way of non- limiting example.
The food supplement for hair care according to the invention is composed of 100% natural ingredients, based on dry apple extract of melannurca and dry extract of Ganoderma lucidum, a mushroom widely used in traditional Chinese medicine, to which Numerous therapeutic properties and the ability to cure a wide variety of ailments are attributed.
According to a preferred embodiment, the food supplement according to the invention has the following composition:
- dry extract of melannurca 0,8 g
- dry extract of Ganoderma lucidum 1 g
- soluble dietary fiber (maltodextrin) 7.2 g The commercial form is preferably a 10ml stick pack.
Melannurca is a fruit that contains a high amount of polyphenols, especially type B procyanidins, responsible for positive health effects. Melannurca extract has given excellent results in the nutri-cosmetic treatment of alopecia, thanks to the abundant amount of procyanidin B2, this active ingredient, in fact, has the ability to stimulate hair regrowth and trophism both in vitro and in vivo, promotes the anagen phase of the life cycle, increases the biosynthesis of keratin and stimulates the stem cells of the outer root sheath, favoring the reorganization of the follicle.
Ganoderma lucidum or Reishi is a mushroom that contains a complex of active ingredients capable of developing some positive effects in favor of the body and the human organism. Reishi contains over 150 active substances with a beneficial effect that support its validity as a natural remedy capable of covering multiple functions, each of which attributable to every single active ingredient contained in it: polysaccharides, oleic acid, ganoderic and pantothenic acid, nucletodes, ergosterols, proteins and peptides. It also has traces of essential micronutrients such as iron, manganese, copper, potassium, calcium and germanium, as well as B vitamins, amino acids, glucose, adenosine, mannose. Alopecia areata is an autoimmune disease that causes patchy hair loss. A study conducted on 22 people affected by this pathology gave significant results, which confirm the healing properties of mushrooms, in this case Ganoderma lucidum. 78.9% of people who were given Ganoderma lucidum found a benefit, 80% had hair regrowth in 12 weeks.
The nutraceutical supplement according to the invention is therefore a 100% natural food supplement, which can be administered orally, in semi-solid pharmaceutical form (gel), produced in single pre-dosed sachets whose formulation is mainly composed of two natural extracts such as: dry extract of melannurca and ganoderma extract in variable percentages depending on the presence of excipients or any additional active ingredients present in minority compositions.
The melannurca extract (both alone and associated with other components such as zinc and selenium) after 60 days of treatment increases the density, size and keratin content of the hair.
Ganoderma lucidum has shown exceptional results in hair regrowth; the constant use of food supplements containing standardized Reishi extract would seem to act on alopecia by counteracting the conversion of the hormone testosterone into dihydrotestosterone (DHT), the latter responsible for androgenetic alopecia (AGA). The new formulation of the natural supplement and the synergistic action of the two active ingredients represent an innovation in the trichology sector. The sources and the molecules selected as active ingredients have shown a strong synergistic action both in the prevention and in the treatment of pathologies and disorders related to health and hair loss. The melannurca extract restores the health and balance of both the skin (scalp) and the hair, amplifying the regrowth action of the Ganoderma lucidum extract. The formulation according to the invention therefore guarantees fast and long-lasting regrowth, giving the hair all the nutrients necessary for its development and fortification.

Claims

1. Food supplement for the nutritious treatment of alopecia, with beneficial effects in cardiovascular prevention and on the body, characterized by having the following composition:
- dry extract of melannurca 0,8 g
- dry extract of Ganoderma lucidum 1 g
- soluble dietary fiber (maltodextrin) 7.2 g
PCT/IT2021/050319 2021-02-19 2021-10-06 Food supplement for a nutri-cosmetic treatment of alopecia and for cardiovascular prevention WO2022175991A1 (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1759683A1 (en) * 2004-05-21 2007-03-07 Furusatomura Development Center Co., Ltd. Scalp and hair-care composition
US10905723B2 (en) * 2017-06-13 2021-02-02 Houn Simon Hsia Compositions and methods for enhancing cancer radiotherapy

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1759683A1 (en) * 2004-05-21 2007-03-07 Furusatomura Development Center Co., Ltd. Scalp and hair-care composition
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