WO2022162966A1 - Dispositif de remplissage d'injecteur - Google Patents

Dispositif de remplissage d'injecteur Download PDF

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Publication number
WO2022162966A1
WO2022162966A1 PCT/JP2021/016350 JP2021016350W WO2022162966A1 WO 2022162966 A1 WO2022162966 A1 WO 2022162966A1 JP 2021016350 W JP2021016350 W JP 2021016350W WO 2022162966 A1 WO2022162966 A1 WO 2022162966A1
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WO
WIPO (PCT)
Prior art keywords
syringe
plunger
filling device
rod
vial
Prior art date
Application number
PCT/JP2021/016350
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English (en)
Japanese (ja)
Inventor
崇 橋爪
Original Assignee
合同会社Teleimage
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 合同会社Teleimage filed Critical 合同会社Teleimage
Publication of WO2022162966A1 publication Critical patent/WO2022162966A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle

Definitions

  • the present invention relates to syringes.
  • syringe For example, vaccination is performed using a syringe (see Patent Documents 1 to 5, for example).
  • the syringe needs to be filled with the drug solution.
  • Syringes are sometimes sold pre-filled with drug solutions, but depending on the type of drug solution, medical professionals such as doctors and nurses must fill the syringes with the drug solution before inoculating patients. .
  • manually filling the syringe with the drug solution each time inoculation increases the workload of the medical staff.
  • One of the objects of the present invention is to provide a syringe filling device capable of automatically filling a syringe with a drug solution.
  • a syringe holder that holds the syringe of the syringe with the plunger of the syringe facing downward in the direction of gravity
  • a vial holder that holds the vial in which the needle of the syringe is inserted
  • a syringe plan and a plunger drive for moving the jar up and down.
  • the plunger drive unit includes a rotating body, a rod connected to the outside of the rotation axis of the rotating body, and a plunger connecting part connected to the rod and connected to the plunger of the syringe. may be provided.
  • the rotating body and the rod may be connected by a pin.
  • the pin that connects the rotating body and the rod may be a hinge pin.
  • the rod and plunger connecting portion may be connected by a pin.
  • the pin that connects the rod and the plunger connecting portion may be a hinge pin.
  • the plunger connection may hold the flange of the plunger.
  • the syringe filling device described above may further include a rotating device that rotates the rotating body.
  • the rotating device may be a motor.
  • the syringe holder may hold the flange of the syringe.
  • the syringe filling device described above may further include a substrate that holds the syringe holder and the vial holder.
  • the substrate may hold the syringe holder and the vial holder substantially parallel to the direction of gravity.
  • a syringe holder that holds the syringe of the syringe with the plunger of the syringe facing downward in the direction of gravity
  • a vial holder that holds the vial in which the needle of the syringe is inserted
  • the syringe a substrate that holds the holder and the vial holder
  • a plunger driving unit that vertically moves the plunger of the syringe, the substrate holding the syringe holder and the vial holder substantially parallel to the direction of gravity
  • a plunger drive comprises a rotating body, a rod connected outside the rotation axis of the rotating body, and a plunger connecting part connected to the rod and connected to a plunger of the syringe, wherein the plunger connecting part is , a fitting part that fits with the plunger, and a rod-shaped part connected to the fitting part, the rotating body and the rod are connected by a first pin, and the rod and the plunger
  • the first pin connecting the rotating body and the rod may be a hinge pin.
  • the second pin connecting the rod and the rod-shaped portion of the plunger connecting portion may be a hinge pin.
  • the fitting portion of the plunger connecting portion may hold the flange of the plunger.
  • the syringe filling device described above may further include a rotating device that rotates the rotating body.
  • the rotating device may be a motor.
  • the syringe holder may hold the flange of the syringe.
  • the above syringe filling device may include a plurality of syringe holders, a plurality of vial holders, and a plunger connection portion may include a plurality of fitting portions.
  • a plurality of fitting portions may be connected.
  • the rod-shaped portion may be connected to a plurality of connected fitting portions.
  • a syringe filling device capable of automatically filling a syringe with a drug solution.
  • FIG. 1 is a schematic front view showing the syringe filling device according to the first embodiment.
  • FIG. 2 is a schematic side view showing the syringe filling device according to the first embodiment.
  • FIG. 3 is a schematic bottom view showing the syringe filling device according to the first embodiment.
  • FIG. 4 is a schematic front view showing the syringe filling device according to the first embodiment.
  • FIG. 5 is a schematic front view showing the syringe filling device according to the first embodiment.
  • FIG. 6 is a schematic front view showing the syringe filling device according to the second embodiment.
  • FIG. 7 is a schematic perspective view showing the syringe filling device according to the second embodiment viewed from below.
  • FIG. 8 is a schematic perspective view showing the syringe filling device according to the second embodiment viewed from above.
  • the syringe filling device includes a syringe holder 21 that holds the syringe 12 of the syringe 10 with the plunger 11 of the syringe 10 facing downward in the direction of gravity, and a syringe It has a vial holder 22 that holds a vial 30 into which a needle 13 of 10 has been inserted, and a plunger driving section 23 that moves the plunger 11 of the syringe 10 up and down.
  • Materials for the syringe 12 and plunger 11 of the syringe 10 are, for example, glass and resin, and are not particularly limited.
  • the capacity and size of the syringe 12 are not particularly limited.
  • a needle 13 is attached to one end of the syringe 12 .
  • the plunger 11 is inserted into the syringe 12 through the opening at the other end of the syringe 12 .
  • the other end of the syringe 12 is provided with a flange 14 that functions as a finger hook.
  • a gasket 15 that is in close contact with the inner wall of the syringe 12 is provided at the end of the plunger 11 that is inserted into the syringe 12 .
  • the material of the gasket 15 is, for example, rubber, but is not particularly limited.
  • the other end of the plunger 11 is provided with a flange 16 that functions as a finger rest.
  • the vial 30 holds the drug solution 50 filled in the syringe 10.
  • the drug solution 50 contains, for example, a virus vaccine. Examples of viruses include coronaviruses, novel coronaviruses, and influenza viruses.
  • the drug contained in the drug solution 50 is not particularly limited.
  • the drug solution 50 may contain an anticancer drug.
  • the vial 30 includes a container 31 containing a drug solution 50 and a lid 32 of the container 31 .
  • the material of the container 31 is, for example, glass and resin, and is not particularly limited.
  • the lid 32 is made of a material through which the needle 13 of the syringe 10 can penetrate, such as rubber, but is not particularly limited. When the needle 13 of the empty syringe 10 is stuck into the cap 32 of the vial 30 , the tip of the needle 13 reaches the drug solution 50 inside the container 31 of the vial 30 .
  • the syringe 12 of the syringe 10 is held by the syringe holder 21 in an empty state.
  • the syringe holder 21 holds the syringe 12 so that the needle 13 of the syringe 10 faces upward in the direction of gravity and the plunger 11 of the syringe 10 faces downward in the direction of gravity.
  • the syringe holder 21 may have a fitting portion that fits with the syringe 12 .
  • the syringe holder 21 may have a shape into which the syringe 12 can be fitted. Also, the syringe holder 21 may hold the flange 14 of the syringe 12 .
  • the vertical movement of the syringe 12 can be suppressed by holding the syringe 12 so that the flanges 14 of the syringe 12 are sandwiched between the syringe holders 21 .
  • the material of the syringe retainer 21 is, for example, resin and metal, but is not particularly limited.
  • the vial holder 22 holds the vial 30 pierced by the needle 13 of the syringe 10.
  • the vial holder 22 holds the vial 30 so that the container 31 of the vial 30 faces upward in the direction of gravity and the lid 32 of the vial 30 faces downward in the direction of gravity.
  • the vial retainer 22 holds the vial 30 so as to support the shoulder of the container 31 of the vial 30 .
  • the vial holder 22 may have a shape into which the vial 30 can be fitted.
  • the mechanism by which the vial holder 22 holds the vial 30 is not particularly limited.
  • the material of the vial holder 22 is, for example, resin and metal, but is not particularly limited.
  • the syringe holder 21 and the vial holder 22 are arranged in series.
  • the syringe filling device according to the first embodiment may further include a substrate 40 holding the syringe holder 21 and the vial holder 22 .
  • the substrate 40 holds the syringe holder 21 and the vial holder 22 substantially parallel to the direction of gravity, for example.
  • the material of the substrate 40 is, for example, resin, metal, and wood, but is not particularly limited.
  • the plunger drive unit 23 includes, for example, a rotating body 231, a rod 232 connected to the outside of the rotation axis of the rotating body 231, and a plunger connecting part 233 connected to the rod 232 and connected to the plunger 11 of the syringe 10. And prepare.
  • Materials for the rotating body 231, the rod 232, and the plunger connecting portion 233 are, for example, resin and metal, but are not particularly limited.
  • the rotating body 231 may be a disc or a crank.
  • the rotating body 231 may be rotated by a rotating device 234 such as a motor.
  • the rod 232 is movably connected to a portion of the rotating body 231 that is not the rotating shaft by a first pin 2334 such as a hinge pin.
  • the plunger connecting portion 233 is movably connected to the rod 232 by a second pin 2333 such as a hinge pin.
  • the plunger connecting portion 233 may include a fitting portion 2332 that fits with the plunger 11, and a rod-shaped portion 2331 connected to the fitting portion.
  • the rod 232 and the rod-shaped portion 2331 of the plunger connecting portion 233 may be connected by the second pin 2333 .
  • the plunger connection portion 233 may also hold the flange 16 of the plunger 11 .
  • the plunger connecting portion 233 holds the flange 16 of the plunger 11 so as to sandwich it from both sides, so that it is possible to apply a force in the vertical direction to the plunger 11 .
  • the rotary motion of the rotating body 231 is converted into vertical motion by the rod 232 and the plunger connecting portion 233 . Therefore, when the rotating body 231 rotates, the end of the plunger 11 connected to the plunger connecting portion 233 reciprocates between the bottom dead center and the top dead center.
  • the syringe 12 of the syringe 10 is held by the syringe holder 21 in an empty state.
  • the plunger 11 of the syringe 10 is designed so that a space remains in the syringe 12 when the syringe 12 is in an empty state and the plunger connecting portion 233 pushes the plunger 11 into the syringe 12 as far as possible. , is connected to the plunger connection portion 233 .
  • the plunger 11 is connected to the plunger connection 233 such that a space remains in the syringe 12 between the top dead center of the gasket 15 and the needle 13 .
  • the drug solution 50 in the vial 30 moves into the syringe 12 as shown in FIG. Since the syringe 10 is arranged with the plunger 11 facing downward in the direction of gravity, the liquid medicine 50 accumulates on the gasket 15 in the syringe 12 and an air layer is formed on the layer of the liquid medicine 50 .
  • the air inside the syringe 12 is pushed out into the vial 30 . Since the vial 30 is arranged so that the lid 32 into which the needle 13 is pierced is located downward in the direction of gravity, air rises above the layer of the liquid medicine 50 in the container 31 of the vial 30 .
  • the rotating body 231 repeats the rotary motion and the plunger 11 repeats the vertical motion, the drug solution 50 in the vial 30 is sucked into the syringe 12 and the air in the syringe 12 is pushed out into the vial 30 repeatedly.
  • the rotating body 231 is stopped.
  • the rotation body 231 may be stopped after confirming that an appropriate amount of the chemical solution 50 has been sucked into the syringe 12 by visual observation.
  • the number of revolutions of the rotating body 231 may be obtained in advance, and the rotating body 231 may be automatically stopped when the predetermined number of revolutions is reached.
  • syringe 10 is removed from syringe holder 21 and plunger driver 23, needle 13 is withdrawn from vial 30, and used to treat a patient. .
  • the distance between the vial holder 22 and the syringe holder 21 on the substrate 40 may be changeable. Also, the distance between the syringe holder 21 and the plunger connection 233 may be variable on the substrate 40 . This makes it possible to adapt to changes in the size of the syringe 12 .
  • the syringe filling device it is possible to automatically fill the syringe with the drug solution, so it is possible to reduce the work burden on the medical staff even in the event of a pandemic. .
  • the syringe filling device according to the second embodiment includes a plurality of vial holders 22A, 22B, 22C, .
  • the plunger connecting portion 233 includes a plurality of fitting portions 2332A, 2332B, 2332C .
  • the substrate 40 holds the plurality of vial holders 22A, 22B, 22C, . Further, the substrate 40 holds the plurality of syringe holders 21A, 21B, 21C, .
  • the substrate 40 holds the plurality of syringe holders 21A, 21B, 21C, ... and the plurality of vial holders 22A, 22B, 22C, ... in parallel in a direction substantially parallel to the direction of gravity.
  • the plurality of fitting portions 2332A, 2332B, 2332C... may be connected to each other.
  • the plurality of fitting portions 2332A, 2332B, 2332C, . . . may be integrated.
  • the rod-shaped portions 2331A, 2331B may be connected to a plurality of connected fitting portions 2332A, 2332B, 2332C, .
  • FIGS. 6 to 8 show examples in which there are two rod-shaped portions, the number of rod-shaped portions may be one, or three or more. In the following, an example with two rod-shaped portions will be described.
  • a rod-shaped portion 2331A of the plunger connecting portion 233 and the rod 232A are connected by a second pin 2333A. Also, the rod 232A and the rotating body 231A are connected by a first pin 2334A.
  • a rod-shaped portion 2331B of the plunger connecting portion 233 and the rod 232B are connected by a second pin 2333B. Also, the rod 232B and the rotor 231B are connected by a first pin 2334B.
  • the rotator 231A and the rotator 231B are connected to the rotating device 234 and rotated simultaneously by the rotating device 234.
  • the method by which each of the plurality of vial holders 22A, 22B, 22C, . . . holds a vial is the same as in the first embodiment.
  • a method for holding a syringe by each of the plurality of syringe holders 21A, 21B, 21C, . . . is the same as in the first embodiment.
  • a plurality of fitting portions 2332A, 2332B, 2332C, . . . of the plunger connecting portion 233 are fitted with a plurality of plungers.
  • a method for fitting each of the plurality of fitting portions 2332A, 2332B, 2332C, . . . to the plunger is the same as in the first embodiment.
  • the rotational motion of the rotating bodies 231A and 231B is converted into vertical motion by the rods 232A and 232B and the plunger connecting portion 233. Therefore, when the rotors 231A and 231B rotate, the ends of the plurality of plungers connected to the plunger connecting portion 233 reciprocate between the bottom dead center and the top dead center. Therefore, according to the syringe filling device according to the second embodiment, it is possible to simultaneously fill a plurality of syringes with liquid medicine.
  • the plunger drive unit 23 may have any mechanism as long as it can move the plunger 11 of the syringe 10 up and down.
  • the present invention encompasses various embodiments and the like not described herein.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Basic Packing Technique (AREA)

Abstract

Ce dispositif de remplissage d'injecteur comporte : un support de seringue 21 qui maintient une seringue 12 d'un injecteur 10 avec le piston plongeur 11 de l'injecteur 10 orienté verticalement vers le bas ; un support de flacon 22 qui maintient un flacon 30 dans lequel l'aiguille 13 de l'injecteur 10 a été insérée ; et une unité d'entraînement de piston plongeur 23 pour déplacer le piston plongeur 11 de l'injecteur 10 vers le haut et vers le bas.
PCT/JP2021/016350 2021-01-27 2021-04-22 Dispositif de remplissage d'injecteur WO2022162966A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2021-010868 2021-01-27
JP2021010868A JP6881807B1 (ja) 2021-01-27 2021-01-27 注射器充填装置

Publications (1)

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WO2022162966A1 true WO2022162966A1 (fr) 2022-08-04

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PCT/JP2021/016350 WO2022162966A1 (fr) 2021-01-27 2021-04-22 Dispositif de remplissage d'injecteur

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JP (1) JP6881807B1 (fr)
WO (1) WO2022162966A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020188273A1 (en) * 2001-06-11 2002-12-12 Kam Ko Vial docking station for sliding reconstitution with diluent container
JP5102350B2 (ja) * 2007-04-30 2012-12-19 メドトロニック ミニメド インコーポレイテッド リザーバ充填／気泡管理／注入媒体送給システムおよび該システムを用いる方法
WO2013108587A1 (fr) * 2012-01-17 2013-07-25 パナソニック株式会社 Procédé de transfusion d'un fluide médical et dispositif de transfusion d'un fluide médical
WO2013157203A1 (fr) * 2012-04-18 2013-10-24 パナソニック株式会社 Dispositif de transfusion de médicament et procédé de transfusion de médicament
US20190221301A1 (en) * 2018-01-12 2019-07-18 Becton, Dickinson And Company Medication dispensing system
CN210750462U (zh) * 2019-06-17 2020-06-16 成都市温江区人民医院 一种自动抽吸式空针

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2580576C (fr) * 2005-01-21 2013-04-23 Avanca Medical Devices, Inc. Seringues a mouvement alternatif
CN102119018B (zh) * 2009-03-31 2014-03-19 松下电器产业株式会社 药剂混合装置及药剂混合方法
JP5180379B2 (ja) * 2009-07-23 2013-04-10 パナソニック株式会社 シリンジ駆動装置及び調剤装置
JP5482038B2 (ja) * 2009-09-07 2014-04-23 パナソニック株式会社 シリンジ駆動装置およびシリンジ駆動方法
EP2332600A1 (fr) * 2009-12-09 2011-06-15 F. Hoffmann-La Roche AG Procédé de remplissage d'un récipient avec un médicament liquide
WO2014129493A1 (fr) * 2013-02-20 2014-08-28 株式会社根本杏林堂 Dispositif d'aspiration de solution chimique actionné mécaniquement

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020188273A1 (en) * 2001-06-11 2002-12-12 Kam Ko Vial docking station for sliding reconstitution with diluent container
JP5102350B2 (ja) * 2007-04-30 2012-12-19 メドトロニック ミニメド インコーポレイテッド リザーバ充填／気泡管理／注入媒体送給システムおよび該システムを用いる方法
WO2013108587A1 (fr) * 2012-01-17 2013-07-25 パナソニック株式会社 Procédé de transfusion d'un fluide médical et dispositif de transfusion d'un fluide médical
WO2013157203A1 (fr) * 2012-04-18 2013-10-24 パナソニック株式会社 Dispositif de transfusion de médicament et procédé de transfusion de médicament
US20190221301A1 (en) * 2018-01-12 2019-07-18 Becton, Dickinson And Company Medication dispensing system
CN210750462U (zh) * 2019-06-17 2020-06-16 成都市温江区人民医院 一种自动抽吸式空针

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Publication number Publication date
JP2022114560A (ja) 2022-08-08
JP6881807B1 (ja) 2021-06-02

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