WO2022160717A1 - Clamping mechanism and transfer device - Google Patents

Clamping mechanism and transfer device Download PDF

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Publication number
WO2022160717A1
WO2022160717A1 PCT/CN2021/116305 CN2021116305W WO2022160717A1 WO 2022160717 A1 WO2022160717 A1 WO 2022160717A1 CN 2021116305 W CN2021116305 W CN 2021116305W WO 2022160717 A1 WO2022160717 A1 WO 2022160717A1
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WO
WIPO (PCT)
Prior art keywords
clamping
clamping mechanism
clamped
limiting
driving member
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PCT/CN2021/116305
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French (fr)
Chinese (zh)
Inventor
张涛
李晓峰
黄宏坤
刘建知
Original Assignee
广东润鹏生物技术有限公司
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Application filed by 广东润鹏生物技术有限公司 filed Critical 广东润鹏生物技术有限公司
Publication of WO2022160717A1 publication Critical patent/WO2022160717A1/en

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02Burettes; Pipettes

Definitions

  • the present application relates to the technical field of analysis and inspection equipment, and in particular, to a clamping mechanism and a transfer device.
  • the basis of molecular detection is to analyze the tissue cells, hair, anticoagulated or dried blood of the subject, as well as the genes and their expression products in formaldehyde-fixed, paraffin-embedded tissues, by completing nucleic acid (DNA and RNA) at the molecular level. ) detection, which can be accurately detected once the disease occurs or even before symptoms, signs and biochemical changes appear.
  • DNA and RNA nucleic acid
  • the traditional operation is to first cover the capillary holder with its end cap by hand, and then use the hand to transfer the capillary holder.
  • the above operations are not only cumbersome, time-consuming and labor-intensive, but also the whole The operation process is easy to contaminate the capillary and affect the purity of the extract.
  • the present disclosure provides a clamping mechanism, which to a certain extent solves the technical problems of low work efficiency and contamination of the capillary tube caused by holding the capillary tube holder in a hand-held manner in the conventional technology.
  • the present disclosure also provides a transfer device, which to a certain extent solves the technical problems of low work efficiency and contamination of the capillary tube caused by the hand-held method of transferring the capillary tube holder in the traditional technology.
  • the present disclosure provides a clamping mechanism configured to clamp a to-be-clamped piece, the top end of the to-be-clamped piece may have a protrusion, and the bottom end of the to-be-clamped piece may have a groove;
  • the The clamping mechanism can include a clamping jaw and a supporting plate;
  • the supporting plate may be located below the clamping jaws, and is at a predetermined distance from the clamping jaws, so that a clamping space is formed between the clamping jaws and the supporting plate;
  • clamping ends of the clamping jaws may be provided with clamping grooves;
  • the support plate may be provided with limiting protrusions;
  • the limiting protrusion is configured to be clamped in the groove.
  • the number of the clamping jaws and the supporting plate is multiple;
  • a plurality of the clamping claws may be arranged at intervals along the first direction, a plurality of the supporting plates may be arranged at intervals along the first direction, and a plurality of the clamping claws and a plurality of the supporting plates may be arranged at intervals.
  • a corresponding setting may be arranged at intervals along the first direction, a plurality of the supporting plates may be arranged at intervals along the first direction, and a plurality of the clamping claws and a plurality of the supporting plates.
  • the number of the clamping jaws and the number of the supporting plate is two respectively.
  • the clamping mechanism may further include a first drive assembly, and the first drive assembly may include a fixed cylinder, a first drive member and a lead screw;
  • the output shaft of the first driving member is connected with the lead screw, and the lead screw is in driving connection with the fixed cylinder;
  • the first driving member is configured to drive the fixing cylinder to move in a second direction through the lead screw, so as to move the clamping jaw and the support plate in the second direction.
  • the clamping mechanism may further include a first support frame and a second support frame disposed inside the first support frame;
  • the first drive member can be arranged on the first support frame, both ends of the fixing cylinder are fixed on the second support frame, and the output shaft of the first drive member can be connected to the second support frame through a lead screw.
  • the second support frame is connected;
  • the first driving member is configured to drive the second support frame to move in a second direction, so that the fixing cylinder moves in conjunction with the jaws and the support plate in the second direction.
  • the first drive assembly may further include an auxiliary member, and the auxiliary member may include a slideway and a slider slidably placed on the slideway;
  • the slideway may be disposed on the end surface of the first support frame facing the second support frame, and the slider may be disposed on the end surface of the second support frame facing the first support frame.
  • the clamping mechanism may further include a limiting member
  • the limiting member can prevent the fixed cylinder from rotating.
  • the limiting member may include a limiting pin
  • the limiting pin is arranged below the fixing cylinder, and a limiting hole is provided on the fixing cylinder at a position corresponding to the limiting pin;
  • the limiting pin is configured to be inserted into or pulled out of the limiting hole.
  • the support plate may be formed of spring steel.
  • the present application provides a transfer device, which may include a second drive assembly and the above-mentioned clamping mechanism;
  • the output shaft of the second drive assembly is connected with the fixed cylinder, and the second drive assembly is configured to drive the fixed cylinder to rotate by a preset angle, so that the clamping mechanism can move the to-be-clamped member from the first position. One position is transferred to the second position.
  • the second driving assembly may include a second driving member
  • the second driving member may be disposed on the second supporting frame, and the output shaft of the second driving member may pass through the second supporting frame and be inserted into the interior of the fixing cylinder;
  • the fixed cylinder rotates by the predetermined angle.
  • a buffer member may also be included, one end of the buffer member abuts on the first support frame, and the other end abuts on the second driving member.
  • the present application provides a clamping mechanism for clamping a to-be-clamped piece, the top end of the to-be-clamped piece has a protrusion, and the bottom end of the to-be-clamped piece has a groove; comprising a clamping claw and a support plate;
  • the supporting plate is located below the clamping jaws and is at a predetermined distance from the clamping jaws, so that a clamping space is formed between the clamping jaws and the supporting plate; the clamping ends of the clamping jaws A clamping groove is provided in the part; a limit protrusion is arranged on the support plate;
  • the clamping mechanism can Clamp the to-be-clamped piece.
  • sample processing module refers to a series of operations from sample pretreatment to nucleic acid purification, to PCR reaction liquid filling, etc., do not do too much here. Explanation, those in the art can understand) inject the PCR reaction body into the capillary, then cover the capillary holder with an end cap to seal the capillary holder, and finally transfer the sealed capillary holder to the thermal cycler module to complete the subsequent PCR process
  • the capillary holder can be clamped by the clamping mechanism. Specifically, when the capillary holder in the kit moves to a preset position, the capillary holder is located in the clamping space.
  • the protrusions are inserted into the clamping grooves, and when the limiting protrusions are clamped in the grooves, the clamping effect of the clamping grooves on the protrusions and the limiting protrusions on the grooves are utilized. Therefore, the stable clamping effect of the clamping mechanism on the capillary stent is realized. It overcomes the technical problems of low work efficiency and contamination of the capillary bracket caused by manually clamping the capillary bracket in the prior art.
  • the use of the clamping mechanism to realize the clamping effect on the capillary rack replaces the manual operation.
  • the operation is simple and the work efficiency is improved; Purity guarantees the accuracy of the results.
  • the application also provides a transfer device, comprising a second drive assembly and the above-mentioned clamping mechanism; an output shaft of the second drive assembly is connected to the fixed cylinder, and the second drive member can drive the fixed cylinder The predetermined angle is rotated to cause the clamping mechanism to transfer the to-be-clamped piece from the first position to the second position.
  • the use of the transfer device can realize the transfer of the capillary stent, which overcomes the manual hand-held transfer method in the prior art. On the one hand, the work efficiency is improved; on the other hand, the capillary stent is not polluted and the extract in the capillary is guaranteed The purity of the results is guaranteed.
  • FIG. 1 is a schematic structural diagram of a clamping mechanism provided in an embodiment of the present application.
  • FIG. 2 is a schematic structural diagram of a to-be-clamped member provided in an embodiment of the present application
  • FIG. 3 is a schematic structural diagram of a clamping mechanism provided in still another embodiment of the present application from a first perspective
  • FIG. 4 is a schematic structural diagram of a clamping mechanism provided in another embodiment of the present application from a second viewing angle
  • FIG. 5 is a schematic structural diagram of a clamping mechanism provided in another embodiment of the present application in a practical application process
  • FIG. 6 is a schematic structural diagram of the clamping mechanism provided in another embodiment of the present application during practical application.
  • FIG. 7 is a schematic structural diagram of a transfer device provided in other embodiments of the present application from a first perspective during practical application;
  • FIG. 8 is a schematic structural diagram of a transfer device provided in other embodiments of the present application from a second perspective during practical application;
  • FIG. 9 is a schematic structural diagram of a to-be-clamped member provided in other embodiments of the present application.
  • the terms “installed”, “connected” and “connected” should be understood in a broad sense, for example, it may be a fixed connection or a detachable connection Connection, or integral connection; can be mechanical connection, can also be electrical connection; can be directly connected, can also be indirectly connected through an intermediate medium, can be internal communication between two elements.
  • installed should be understood in a broad sense, for example, it may be a fixed connection or a detachable connection Connection, or integral connection; can be mechanical connection, can also be electrical connection; can be directly connected, can also be indirectly connected through an intermediate medium, can be internal communication between two elements.
  • the present application provides a clamping mechanism, which can clamp the capillary holder 100 on the reagent kit 119 .
  • the top of the capillary holder 100 may have a protrusion 101, and its bottom end has a groove 102; as shown in FIG. 1, the clamping mechanism may include a clamping jaw 104 and a supporting plate 106; the supporting plate 106 may be located below the clamping jaw 104, and the distance
  • the clamping jaws 104 have a preset distance so that a clamping space 107 is formed between the clamping jaws 104 and the support plate 106 ; optionally, the clamping ends of the clamping jaws 104 can be opened along the length direction thereof.
  • clamping groove 108 There is a clamping groove 108, preferably, the length of the clamping groove 108 is equal to the length of the protrusion 101; the support plate 106 can be provided with a limiting protrusion 105, and the position of the limiting protrusion 105 and the groove 102 is the same correspond.
  • sample processing module refers to a series of operations from sample pretreatment to nucleic acid purification, to PCR reaction liquid filling, etc., do not do too much here.
  • the PCR reaction body is injected into the capillary, and then the capillary holder needs to be covered with the end cap 103 to achieve the sealing of the capillary holder 100, and finally the sealed capillary holder 100 is transferred to the thermal cycler module
  • the subsequent PCR process is completed; in this embodiment, the capillary holder can be clamped by the clamping mechanism.
  • the protrusion 101 is inserted into the clamping groove 108, and when the limiting protrusion 105 is clamped in the groove 102, the clamping groove 108 is used for the protrusion 101.
  • the clamping effect of the capillary tube holder 100 and the limiting effect of the limiting protrusion 105 on the groove 102 are realized, so as to realize the stable clamping effect of the clamping mechanism on the capillary holder 100 .
  • the technical problem of low work efficiency and contamination of the capillary holder 100 caused by manually holding the capillary holder 100 in the prior art is overcome.
  • the support plate 106 can be formed of spring steel, and the support plate 106 formed of the spring steel material has a certain elastic force, which can generate a clamping force when the clamping jaws 104 cooperate, on the one hand, it does not affect the The capillary holder 100 enters the limiting space, and on the other hand, it can ensure that the limiting protrusion 105 is clamped in the groove 102 .
  • the width of the capillary holder 100 is affected by the number of capillaries. If the capillary holder 100 is too wide, in order to ensure the stable clamping of the capillary holder 100 by the clamping mechanism, a In this embodiment, the number of the clamping jaws 104 and the supporting plate 106 can be set in multiples; the clamping jaws 104 can be in one-to-one correspondence with the supporting plates 106 , that is, using a plurality of clamping jaws 104 The clamping jaws 104 and the plurality of supporting plates 106 realize stable clamping of the capillary holder 100 with multi-point positioning.
  • a plurality of the clamping jaws 104 and the plurality of the supporting plates 106 are arranged at intervals along a first direction 109 , and the first direction 109 refers to the width extension direction of the capillary holder 100 .
  • the number of the clamping jaws 104 and the supporting plate 106 is two respectively, which are the first clamping jaw 110 , the first supporting plate, the second clamping jaw 111 and the second supporting plate, respectively.
  • the same example applies.
  • the capillary holder 100 needs to be covered with the end cap 103 to seal the capillary holder 100;
  • the clamping mechanism holding the capillary holder 100 needs to be driven to move in the second direction 118 (moves close to the end cap 103), so as to realize the capillary capillary holder 100 cap 103 capping operation.
  • the clamping mechanism may further include a first drive assembly, and the first drive assembly may include a fixed cylinder 115, a first drive member 116 and a lead screw 117, preferably,
  • the first driving member 116 may be a first motor, the output shaft of the first motor is connected to the lead screw 117 , the fixing cylinder 115 is provided with a threaded hole, and the fixing cylinder 115 is sleeved on the lead screw 117 , and is threadedly connected with the lead screw 117;
  • the fixing cylinder 115 is provided with a first clamping jaw 110 and a second clamping jaw 111 at intervals along the first direction 109, and a first supporting plate is arranged below the first clamping jaw 110 , a second supporting plate is arranged below the second clamping jaw 111 .
  • the first motor can drive the fixing cylinder 115 to move in the second direction 118 through the lead screw 117 , so that the first clamping jaw 110 and the first support plate 106 can move along the second direction 118 .
  • the two directions 118 move, preferably, the second direction 118 refers to the vertical upward or vertical downward direction in the normal working state of the clamping mechanism.
  • the end cap 103 can be located on one side of the capillary holder 100, and the height of the end cap 103 is smaller than the height of the capillary holder 100.
  • the clamping mechanism first clamps the capillary holder 100; Then the first motor drives the fixing cylinder 115 to move in the vertical downward direction, so that the groove 102 at the bottom of the capillary holder 100 is inserted into the protrusion 101 at the bottom of the end cap 103 , and finally the end cap 103 of the capillary holder 100 is covered.
  • the capillary holder 100 can be clamped; set operation.
  • the first drive assembly may include a fixed cylinder 115, a first drive member 116, a first support frame 112, and a second support frame 113 disposed inside the first support frame 112.
  • the first drive member 116 may be The first motor; the first drive member 116 can be disposed on the top of the first support frame 112, the two ends of the fixing cylinder 115 are fixed on the second support frame 113, the first drive member 116
  • the output shaft is connected with the second support frame 113 through the lead screw 117, that is, when the first motor is driven, the lead screw 117 can drive the second support frame 113 to move in the second direction 118, when the second support frame 113 moves along the second direction 118
  • the fixing cylinder 115 can cooperate with the clamping jaw 104 and the support plate 106 to move along the second direction 118 , thereby realizing the capillary 100 cap 103 being covered.
  • the clamping mechanism may further include an auxiliary member 125, and the auxiliary member 125 may include a slideway 126 and a sliding The slider 127 placed on the slideway 126; the slideway 126 can be arranged on the end surface of the first support frame 112 facing the second support frame 113, and the slider 127 can be arranged on the The second support frame 113 faces the end surface of the first support frame 112 .
  • the second support frame 113 can not only achieve stable sliding on the first support frame 112 , but also give a certain guiding effect to the second support frame 113 .
  • the clamping mechanism further includes a limiting member; when the clamping jaws 104 and the support plate 106 clamp the to-be-clamped When it is installed, the limiting member can prevent the fixed cylinder 115 from rotating.
  • the limiting member may be a limiting pin 129 ; the limiting pin 129 may be disposed below the fixing cylinder 115 , and a limiting position is provided on the fixing cylinder 115 corresponding to the limiting pin 129 hole.
  • the limiting pin 129 can be inserted into or pulled out of the limiting hole.
  • the limit pin 129 can be rotated into the limiting hole, and the fixing cylinder 115 is limited at this time; when the clamping jaw 104 grabs the capillary holder 100 and After the capping action of the end cap 103 is completed, when moving upward along the second direction 118 , the limiting pin 129 leaves the limiting hole.
  • the capillary holder 100 needs to be transferred to a PCR thermal cycling module (PCR thermal cycling module is the core technology of rapid molecular detection) to achieve Thermal cycling of the capillary holder 100, in order to facilitate the transfer of the capillary holder 100 to the PCR thermal cycling module, the present application also provides a transfer device comprising a second drive assembly and the above-mentioned clamping mechanism; the output of the second drive assembly
  • the shaft is connected with the fixing cylinder 115, and the second driving member 131 can drive the fixing cylinder 115 to rotate by a preset angle so that the clamping mechanism transfers the to-be-clamped member from the first position to the second position .
  • using the transfer device can realize the transfer of the capillary support 100, which overcomes the manual hand-held transfer method in the prior art, on the one hand, improves the work efficiency; on the other hand, ensures that the capillary support 100 is not polluted.
  • the fixing cylinder 115 is fixed on the second support frame 113, the space on the upper part of the fixing cylinder 115 is limited, preferably, the fixing cylinder 115 can rotate counterclockwise during the rotation process, that is, the second driving member 131 drives the fixing cylinder 115 to rotate.
  • the barrel 115 rotates in a counterclockwise direction.
  • the first position refers to the position where the capillary holder 100 in the reagent kit 119 is located on one side of the second support frame 113
  • the second position refers to the position on the other side of the second support frame 113 .
  • the position of the supporting portion for supporting the capillary holder 100 is not limited to the first position.
  • the preset angle may be 180°.
  • the second driving assembly may include a second driving member 131; the second driving member 131 may be disposed on the second supporting frame 113, and the output shaft of the second driving member 131 may be Passing through the second support frame 113 and inserted into the interior of the fixing cylinder 115 ; preferably, the second driving member 131 may be a second motor.
  • the fixed cylinder 115 can be rotated by the predetermined angle.
  • the transfer member may further include a buffer 132, so One end of the buffer member 132 can abut on the first support frame 112, and the other end can abut on the second driving member 131; to shock absorption.
  • the present application may also be provided with a supporting platform 133 , and the clamping mechanism may be provided on the supporting platform 133 .
  • the clamping effect on the capillary tube holder is realized, which replaces the manual operation.
  • the operation is simple and the work efficiency is improved;
  • the purity of the material ensures the accuracy of the results.
  • the transfer device provided according to the present application can realize the transfer of the capillary stent, which overcomes the manual hand-held transfer method in the prior art.
  • the gripping mechanisms, transfer devices, etc. of the present application are reproducible and can be used in a variety of industrial applications.
  • the clamping mechanism of the present application can be applied to clamp a capillary rack.

Abstract

The present application relates to the technical field of analysis and inspection equipment, and in particular, to a clamping mechanism and a transfer device. The clamping mechanism comprises a clamping jaw and a bearing plate. The bearing plate is located below the clamping jaw, and a clamping space is formed between the clamping jaw and the bearing plate; a clamping slot is formed in a clamping end of the clamping jaw; a limiting protrusion is provided on the bearing plate; when a piece to be clamped is located in the clamping space, the protrusion is inserted into the clamping slot, and the limiting protrusion is clamped in the groove, the clamping mechanism can clamp said piece. The clamping mechanism is used for clamping said piece, manual operation is replaced, on one hand, the working efficiency is improved, and on the other hand, it is guaranteed that said piece is not polluted.

Description

夹持机构以及转移装置Clamping mechanism and transfer device
相关申请的交叉引用CROSS-REFERENCE TO RELATED APPLICATIONS
本申请要求于2021年1月29日提交中国专利局的申请号为202110129518.5、名称为“夹持机构以及转移装置”的中国专利申请的优先权,其全部内容通过引用结合在本申请中。This application claims the priority of the Chinese Patent Application No. 202110129518.5 and entitled "Clamping Mechanism and Transfer Device" filed with the China Patent Office on January 29, 2021, the entire contents of which are incorporated herein by reference.
技术领域technical field
本申请涉及分析检验设备技术领域,尤其是涉及一种夹持机构以及转移装置。The present application relates to the technical field of analysis and inspection equipment, and in particular, to a clamping mechanism and a transfer device.
背景技术Background technique
分子检测的基础是分析被检测者的组织细胞、毛发、抗凝血或干血迹,以及甲醛固定、石蜡包埋的组织中的基因及其表达产物,通过从分子水平上完成核酸(DNA和RNA)检测,在疾病一旦发生甚至尚未出现症状、体征及生化改变之前,就能准确的做出检测。The basis of molecular detection is to analyze the tissue cells, hair, anticoagulated or dried blood of the subject, as well as the genes and their expression products in formaldehyde-fixed, paraffin-embedded tissues, by completing nucleic acid (DNA and RNA) at the molecular level. ) detection, which can be accurately detected once the disease occurs or even before symptoms, signs and biochemical changes appear.
首先对样本进行核酸提取,然后将核酸提取液导入至复溶舱室进行复溶,最后将复溶后的液体导入至利用毛细管支架承托的毛细管内,后续对毛细管进行样本处理、物理处理、加热处理以及转移处理等一系列操作。First, extract nucleic acid from the sample, then introduce the nucleic acid extract into the reconstitution chamber for reconstitution, and finally introduce the reconstituted liquid into the capillary tube supported by the capillary bracket, and then carry out sample processing, physical processing, and heating on the capillary tube. A series of operations such as processing and transfer processing.
然而在对毛细管进行转移处理时,传统的操作是对毛细管支架首先采用手持方式对其端盖进行盖设操作,然后采用手持方式对毛细管支架进行转移操作,以上操作不仅繁琐、费时费力,并且整个操作过程容易对毛细管造成污染,影响提取物的纯度。However, when transferring the capillary, the traditional operation is to first cover the capillary holder with its end cap by hand, and then use the hand to transfer the capillary holder. The above operations are not only cumbersome, time-consuming and labor-intensive, but also the whole The operation process is easy to contaminate the capillary and affect the purity of the extract.
发明内容SUMMARY OF THE INVENTION
本公开提供了一种夹持机构,以在一定程度上解决了传统技术中采用手持的方式夹持毛细管支架所导致的工作效率低且污染毛细管的技术问题。The present disclosure provides a clamping mechanism, which to a certain extent solves the technical problems of low work efficiency and contamination of the capillary tube caused by holding the capillary tube holder in a hand-held manner in the conventional technology.
本公开还提供了一种转移装置,以在一定程度上解决了传统技术中采用手持的方式转移毛细管支架所导致的工作效率低且污染毛细管的技术问题。The present disclosure also provides a transfer device, which to a certain extent solves the technical problems of low work efficiency and contamination of the capillary tube caused by the hand-held method of transferring the capillary tube holder in the traditional technology.
基于第一目的,本公开提供了一种夹持机构,构造成用于夹持待夹持件,所述待夹持件的顶端可以具有凸起,且其底端可以具有凹槽;所述夹持机构可以包括夹爪和承托板;Based on the first object, the present disclosure provides a clamping mechanism configured to clamp a to-be-clamped piece, the top end of the to-be-clamped piece may have a protrusion, and the bottom end of the to-be-clamped piece may have a groove; the The clamping mechanism can include a clamping jaw and a supporting plate;
所述承托板可以位于所述夹爪的下方,且距离所述夹爪预设距离,以使所述夹爪与所述承托板之间形成夹持空间;The supporting plate may be located below the clamping jaws, and is at a predetermined distance from the clamping jaws, so that a clamping space is formed between the clamping jaws and the supporting plate;
所述夹爪的夹持端部可以开设有夹持槽;所述承托板上可以设置有限位凸起;The clamping ends of the clamping jaws may be provided with clamping grooves; the support plate may be provided with limiting protrusions;
当所述待夹持件位于所述夹持空间内,且所述凸起构造成插入所述夹持槽内,所述限位凸起构造成卡设于所述凹槽内。When the to-be-clamped member is located in the clamping space, and the protrusion is configured to be inserted into the clamping groove, the limiting protrusion is configured to be clamped in the groove.
在上述技术方案中,可选地,所述夹爪以及所述承托板的数量均为多个;In the above technical solution, optionally, the number of the clamping jaws and the supporting plate is multiple;
多个所述夹爪可以沿所述第一方向间隔排布,多个所述承托板沿所述第一方向间隔排布,且多个所述夹爪与多个所述承托板一一对应设置。A plurality of the clamping claws may be arranged at intervals along the first direction, a plurality of the supporting plates may be arranged at intervals along the first direction, and a plurality of the clamping claws and a plurality of the supporting plates may be arranged at intervals. A corresponding setting.
在上述技术方案中,进一步地,所述夹爪与所述承托板的数量分别为两个。In the above technical solution, further, the number of the clamping jaws and the number of the supporting plate is two respectively.
在上述技术方案中,可选地,所述夹持机构还可以包括第一驱动组件,所述第一驱动组件可以包括固定筒、第一驱动件以及丝杠;In the above technical solution, optionally, the clamping mechanism may further include a first drive assembly, and the first drive assembly may include a fixed cylinder, a first drive member and a lead screw;
所述第一驱动件的输出轴与所述丝杠连接,所述丝杠与所述固定筒传动连接;The output shaft of the first driving member is connected with the lead screw, and the lead screw is in driving connection with the fixed cylinder;
所述第一驱动件构造成通过所述丝杠驱动所述固定筒沿第二方向运动,以使所述夹爪以及所述承托板沿所述第二方向运动。The first driving member is configured to drive the fixing cylinder to move in a second direction through the lead screw, so as to move the clamping jaw and the support plate in the second direction.
在上述技术方案中,可选地,所述夹持机构还可以包括第一支撑框架以及设置于所述第一支撑框架内部的第二支撑框架;In the above technical solution, optionally, the clamping mechanism may further include a first support frame and a second support frame disposed inside the first support frame;
所述第一驱动件可以设置于所述第一支撑框架上,所述固定筒的两端固定于所述第二支撑框架上,所述第一驱动件的输出轴可以通过丝杠与所述第二支撑框架连接;The first drive member can be arranged on the first support frame, both ends of the fixing cylinder are fixed on the second support frame, and the output shaft of the first drive member can be connected to the second support frame through a lead screw. The second support frame is connected;
所述第一驱动件构造成驱动所述第二支撑框架沿第二方向运动,以使所述固定筒协同所述夹爪以及所述承托板沿第二方向运动。The first driving member is configured to drive the second support frame to move in a second direction, so that the fixing cylinder moves in conjunction with the jaws and the support plate in the second direction.
在上述技术方案中,可选地,所述第一驱动组件还可以包括辅助件,所述辅助件可以包括滑道以及滑动置于所述滑道上的滑块;In the above technical solution, optionally, the first drive assembly may further include an auxiliary member, and the auxiliary member may include a slideway and a slider slidably placed on the slideway;
所述滑道可以设置于所述第一支撑框架朝向所述第二支撑框架的端面上,所述滑块可以设置于所述第二支撑框架朝向所述第一支撑框架的端面上。The slideway may be disposed on the end surface of the first support frame facing the second support frame, and the slider may be disposed on the end surface of the second support frame facing the first support frame.
在上述技术方案中,可选地,所述夹持机构还可以包括限位构件;In the above technical solution, optionally, the clamping mechanism may further include a limiting member;
当所述夹爪以及所述承托板夹持所述待夹持件时,所述限位构件能够防止所述固定筒旋转。When the clamping jaw and the support plate clamp the to-be-clamped piece, the limiting member can prevent the fixed cylinder from rotating.
在上述技术方案中,可选地,所述限位构件可以包括限位销;In the above technical solution, optionally, the limiting member may include a limiting pin;
所述限位销设置于所述固定筒的下方,所述固定筒上对应所述限位销的位置开设有限位孔;The limiting pin is arranged below the fixing cylinder, and a limiting hole is provided on the fixing cylinder at a position corresponding to the limiting pin;
当所述第一驱动件驱动所述固定筒沿所述第二方向运动时,所述限位销构造成插设或拔出于所述限位孔。When the first driving member drives the fixing cylinder to move in the second direction, the limiting pin is configured to be inserted into or pulled out of the limiting hole.
在上述技术方案中,可选地,所述承托板可以由弹簧钢形成。In the above technical solution, optionally, the support plate may be formed of spring steel.
基于第二目的,本申请提供一种转移装置,可以包括第二驱动组件以及上述的夹持机构;Based on the second objective, the present application provides a transfer device, which may include a second drive assembly and the above-mentioned clamping mechanism;
所述第二驱动组件的输出轴与所述固定筒连接,所述第二驱动组件构造成驱动所述固定筒旋转预设角度,以使所述夹持机构将所述待夹持件从第一位置转移到第二位置。The output shaft of the second drive assembly is connected with the fixed cylinder, and the second drive assembly is configured to drive the fixed cylinder to rotate by a preset angle, so that the clamping mechanism can move the to-be-clamped member from the first position. One position is transferred to the second position.
在上述技术方案中,可选地,所述第二驱动组件可以包括第二驱动件;In the above technical solution, optionally, the second driving assembly may include a second driving member;
所述第二驱动件可以设置于所述第二支撑框架上,所述第二驱动件的输出轴可以穿过所述第二支撑框架并插设至所述固定筒的内部;The second driving member may be disposed on the second supporting frame, and the output shaft of the second driving member may pass through the second supporting frame and be inserted into the interior of the fixing cylinder;
当所述第二驱动件驱动所述输出轴旋转所述预设角度时,所述固定筒旋转所述预设角度。When the second driving member drives the output shaft to rotate by the predetermined angle, the fixed cylinder rotates by the predetermined angle.
在上述技术方案中,可选地,还可以包括缓冲件,所述缓冲件的一端抵接在所述第一支撑 框架上,且另一端抵接在所述第二驱动件上。In the above technical solution, optionally, a buffer member may also be included, one end of the buffer member abuts on the first support frame, and the other end abuts on the second driving member.
与现有技术相比,本申请的有益效果至少为:Compared with the prior art, the beneficial effects of the present application are at least:
本申请提供了一种夹持机构,用于夹持待夹持件,所述待夹持件的顶端具有凸起,且其底端具有凹槽;包括夹爪和承托板;The present application provides a clamping mechanism for clamping a to-be-clamped piece, the top end of the to-be-clamped piece has a protrusion, and the bottom end of the to-be-clamped piece has a groove; comprising a clamping claw and a support plate;
所述承托板位于所述夹爪的下方,且距离所述夹爪预设距离,以使所述夹爪与所述承托板之间形成夹持空间;所述夹爪的夹持端部开设有夹持槽;所述承托板上设置有限位凸起;The supporting plate is located below the clamping jaws and is at a predetermined distance from the clamping jaws, so that a clamping space is formed between the clamping jaws and the supporting plate; the clamping ends of the clamping jaws A clamping groove is provided in the part; a limit protrusion is arranged on the support plate;
当所述待夹持件位于所述夹持空间内,且所述凸起插入所述夹持槽内,所述限位凸起卡设于所述凹槽内时,所述夹持机构能够将所述待夹持件夹起。When the piece to be clamped is located in the clamping space, the protrusion is inserted into the clamping groove, and the limiting protrusion is clamped in the groove, the clamping mechanism can Clamp the to-be-clamped piece.
在实际的使用过程中,当通过样本处理模块(样品处理模块是现有技术,是指从样本预处理到核酸提纯,再到PCR反应液灌装等一系列操作,在此不做过多的阐述,本领域人员都能够理解)将PCR反应体注入到毛细管中,然后需要将毛细管架盖上端盖,以实现对毛细管支架密封,最后将密封的毛细管支架转移至热循环模块上完成后续PCR过程;在该实施例中利用夹持机构能够实现对毛细管架的夹持作用,具体地,当试剂盒中的毛细管支架运动到预设位置时,使得毛细管支架位于所述夹持空间内,此时所述凸起插入至所述夹持槽内,所述限位凸起卡设于所述凹槽内时,利用夹持槽对凸起的夹持作用以及限位凸起对凹槽的限位作用,从而实现所述夹持机构对毛细管支架的稳定夹持作用。克服了现有技术中,采用人工夹持毛细管支架而导致工作效率低且污染毛细管支架的技术问题。In the actual use process, when the sample processing module (sample processing module is the prior art, refers to a series of operations from sample pretreatment to nucleic acid purification, to PCR reaction liquid filling, etc., do not do too much here. Explanation, those in the art can understand) inject the PCR reaction body into the capillary, then cover the capillary holder with an end cap to seal the capillary holder, and finally transfer the sealed capillary holder to the thermal cycler module to complete the subsequent PCR process In this embodiment, the capillary holder can be clamped by the clamping mechanism. Specifically, when the capillary holder in the kit moves to a preset position, the capillary holder is located in the clamping space. The protrusions are inserted into the clamping grooves, and when the limiting protrusions are clamped in the grooves, the clamping effect of the clamping grooves on the protrusions and the limiting protrusions on the grooves are utilized. Therefore, the stable clamping effect of the clamping mechanism on the capillary stent is realized. It overcomes the technical problems of low work efficiency and contamination of the capillary bracket caused by manually clamping the capillary bracket in the prior art.
综上,利用夹持机构实现对毛细管架的夹持作用,取代了人工操作,一方面,操作简单,提高了工作效率,另一方面,保证了毛细管不受污染,保证毛细管内的提取物的纯度,保证结果的精准度。In summary, the use of the clamping mechanism to realize the clamping effect on the capillary rack replaces the manual operation. On the one hand, the operation is simple and the work efficiency is improved; Purity guarantees the accuracy of the results.
本申请还提供了一种转移装置,包括第二驱动组件以及上述的夹持机构;所述第二驱动组件的输出轴与所述固定筒连接,所述第二驱动件能够驱动所述固定筒旋转预设角度,以使所述夹持机构将所述待夹持件从第一位置转移到第二位置。The application also provides a transfer device, comprising a second drive assembly and the above-mentioned clamping mechanism; an output shaft of the second drive assembly is connected to the fixed cylinder, and the second drive member can drive the fixed cylinder The predetermined angle is rotated to cause the clamping mechanism to transfer the to-be-clamped piece from the first position to the second position.
利用转移装置能够实现对毛细管支架的转移,克服了现有技术中采用人工手持转移的方式,一方面,提高了工作效率;另一方面,保证了毛细管支架不被污染,保证毛细管内的提取物的纯度,保证结果的精准度。The use of the transfer device can realize the transfer of the capillary stent, which overcomes the manual hand-held transfer method in the prior art. On the one hand, the work efficiency is improved; on the other hand, the capillary stent is not polluted and the extract in the capillary is guaranteed The purity of the results is guaranteed.
附图说明Description of drawings
为了更清楚地说明本申请具体实施方式或现有技术中的技术方案,下面将对具体实施方式或现有技术描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图是本申请的一些实施方式,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。In order to more clearly illustrate the specific embodiments of the present application or the technical solutions in the prior art, the accompanying drawings that need to be used in the description of the specific embodiments or the prior art will be briefly introduced below. The drawings are some embodiments of the present application. For those of ordinary skill in the art, other drawings can also be obtained from these drawings without any creative effort.
图1为本申请在一实施例中提供的夹持机构的结构示意图;1 is a schematic structural diagram of a clamping mechanism provided in an embodiment of the present application;
图2为本申请在一实施例中提供的待夹持件的结构示意图;2 is a schematic structural diagram of a to-be-clamped member provided in an embodiment of the present application;
图3为本申请在再一实施例中提供的夹持机构在第一视角下的结构示意图;FIG. 3 is a schematic structural diagram of a clamping mechanism provided in still another embodiment of the present application from a first perspective;
图4为本申请在再一实施例中提供的夹持机构在第二视角下的结构示意图;FIG. 4 is a schematic structural diagram of a clamping mechanism provided in another embodiment of the present application from a second viewing angle;
图5为本申请在再一实施例中提供的夹持机构在实际应用过程中的结构示意图;FIG. 5 is a schematic structural diagram of a clamping mechanism provided in another embodiment of the present application in a practical application process;
图6为本申请在另外的实施例中提供的夹持机构在实际应用过程中的结构示意图;FIG. 6 is a schematic structural diagram of the clamping mechanism provided in another embodiment of the present application during practical application;
图7为本申请在其他的实施例中提供的转移装置在实际应用过程中的第一视角下的结构示意图;7 is a schematic structural diagram of a transfer device provided in other embodiments of the present application from a first perspective during practical application;
图8为本申请在其他的实施例中提供的转移装置在实际应用过程中的第二视角下的结构示意图;8 is a schematic structural diagram of a transfer device provided in other embodiments of the present application from a second perspective during practical application;
图9为本申请在其他的实施例中提供的待夹持件的结构示意图。FIG. 9 is a schematic structural diagram of a to-be-clamped member provided in other embodiments of the present application.
图中:100-毛细管支架;101-凸起;102-凹槽;103-端盖;104-夹爪;105-限位凸起;106-承托板;107-夹持空间;108-夹持槽;109-第一方向;110-第一夹爪;111-第二夹爪;112-第一支撑框架;113-第二支撑框架;115-固定筒;116-第一驱动件;117-丝杠;118-第二方向;119-试剂盒;125-辅助件;126-滑道;127-滑块;129-限位销;131-第二驱动件;132-缓冲件;133-支撑平台。In the figure: 100-capillary bracket; 101-protrusion; 102-groove; 103-end cover; 104-claw; 105-limiting protrusion; 106-supporting plate; 107-clamping space; 108-clamp 109-first direction; 110-first clamping jaw; 111-second clamping jaw; 112-first supporting frame; 113-second supporting frame; 115-fixing cylinder; 116-first driving member; 117 - Lead screw; 118 - Second direction; 119 - Kit; 125 - Auxiliary part; 126 - Slide way; 127 - Slider; 129 - Limit pin; Support platform.
具体实施方式Detailed ways
下面将结合附图对本申请的技术方案进行清楚、完整地描述,显然,所描述的实施例是本申请一部分实施例,而不是全部的实施例。基于本申请中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本申请保护的范围。The technical solutions of the present application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present application, but not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present application.
在本申请的描述中,需要说明的是,术语“中心”、“上”、“下”、“左”、“右”、“竖直”、“水平”、“内”、“外”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本申请和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本申请的限制。此外,术语“第一”、“第二”、“第三”仅用于描述目的,而不能理解为指示或暗示相对重要性。In the description of this application, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the accompanying drawings, which is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the indicated device or element must have a specific orientation or a specific orientation. construction and operation, and therefore should not be construed as limitations on this application. Furthermore, the terms "first", "second", and "third" are used for descriptive purposes only and should not be construed to indicate or imply relative importance.
在本申请的描述中,需要说明的是,除非另有明确的规定和限定,术语“安装”、“相连”、“连接”应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或一体地连接;可以是机械连接,也可以是电连接;可以是直接相连,也可以通过中间媒介间接相连,可以是两个元件内部的连通。对于本领域的普通技术人员而言,可以具体情况理解上述术语在本申请中的具体含义。In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installed", "connected" and "connected" should be understood in a broad sense, for example, it may be a fixed connection or a detachable connection Connection, or integral connection; can be mechanical connection, can also be electrical connection; can be directly connected, can also be indirectly connected through an intermediate medium, can be internal communication between two elements. For those of ordinary skill in the art, the specific meanings of the above terms in this application can be understood in specific situations.
根据本申请的一种实施例,本申请提供一种夹持机构,夹持机构能够夹持试剂盒119上的毛细管支架100,结合图2所示,所述毛细管支架100的顶端可以具有凸起101,且其底端具 有凹槽102;结合图1所示,夹持机构可以包括夹爪104和承托板106;所述承托板106可以位于所述夹爪104的下方,且距离所述夹爪104预设距离,以使所述夹爪104与所述承托板106之间形成夹持空间107;可选地,所述夹爪104的夹持端部可以沿其长度方向开设有夹持槽108,优选地,夹持槽108的长度与凸起101的长度相等;所述承托板106上可以设置有限位凸起105,限位凸起105与凹槽102的位置相对应。According to an embodiment of the present application, the present application provides a clamping mechanism, which can clamp the capillary holder 100 on the reagent kit 119 . As shown in FIG. 2 , the top of the capillary holder 100 may have a protrusion 101, and its bottom end has a groove 102; as shown in FIG. 1, the clamping mechanism may include a clamping jaw 104 and a supporting plate 106; the supporting plate 106 may be located below the clamping jaw 104, and the distance The clamping jaws 104 have a preset distance so that a clamping space 107 is formed between the clamping jaws 104 and the support plate 106 ; optionally, the clamping ends of the clamping jaws 104 can be opened along the length direction thereof. There is a clamping groove 108, preferably, the length of the clamping groove 108 is equal to the length of the protrusion 101; the support plate 106 can be provided with a limiting protrusion 105, and the position of the limiting protrusion 105 and the groove 102 is the same correspond.
在实际的使用过程中,当通过样本处理模块(样品处理模块是现有技术,是指从样本预处理到核酸提纯,再到PCR反应液灌装等一系列操作,在此不做过多的阐述,本领域人员都能够理解)将PCR反应体注入到毛细管中,然后需要将毛细管架盖上端盖103,以实现对毛细管支架100的密封,最后将密封的毛细管支架100转移至热循环模块上完成后续PCR过程;在该实施例中利用夹持机构能够实现对毛细管架的夹持作用,具体地,当试剂盒119中的毛细管支架100运动到预设位置时,使得毛细管支架100位于所述夹持空间107内,此时所述凸起101插入至所述夹持槽108内,所述限位凸起105卡设于所述凹槽102内时,利用夹持槽108对凸起101的夹持作用以及限位凸起105对凹槽102的限位作用,从而实现所述夹持机构对毛细管支架100的稳定夹持作用。克服了现有技术中采用人工手持毛细管支架100而导致工作效率低且污染毛细管支架100的技术问题。In the actual use process, when the sample processing module (sample processing module is the prior art, refers to a series of operations from sample pretreatment to nucleic acid purification, to PCR reaction liquid filling, etc., do not do too much here. Explanation, those in the art can understand) the PCR reaction body is injected into the capillary, and then the capillary holder needs to be covered with the end cap 103 to achieve the sealing of the capillary holder 100, and finally the sealed capillary holder 100 is transferred to the thermal cycler module The subsequent PCR process is completed; in this embodiment, the capillary holder can be clamped by the clamping mechanism. In the clamping space 107, at this time, the protrusion 101 is inserted into the clamping groove 108, and when the limiting protrusion 105 is clamped in the groove 102, the clamping groove 108 is used for the protrusion 101. The clamping effect of the capillary tube holder 100 and the limiting effect of the limiting protrusion 105 on the groove 102 are realized, so as to realize the stable clamping effect of the clamping mechanism on the capillary holder 100 . The technical problem of low work efficiency and contamination of the capillary holder 100 caused by manually holding the capillary holder 100 in the prior art is overcome.
综上,利用夹持机构实现对毛细管支架100的夹持作用,取代了人工操作,一方面提高了工作效率,另一方面,保证了毛细管不受污染,使得结果更精准。In conclusion, using the clamping mechanism to realize the clamping effect on the capillary holder 100 replaces manual operation, on the one hand, the work efficiency is improved, and on the other hand, the capillary is not polluted, and the result is more accurate.
在该实施例中,所述承托板106可以由弹簧钢形成,弹簧钢材料形成的承托板106具有一定的弹力,其在于夹爪104配合时,能够产生夹紧力,一方面不影响毛细管支架100进入到限位空间内,另一方面能够保证限位凸起105卡设在凹槽102内。In this embodiment, the support plate 106 can be formed of spring steel, and the support plate 106 formed of the spring steel material has a certain elastic force, which can generate a clamping force when the clamping jaws 104 cooperate, on the one hand, it does not affect the The capillary holder 100 enters the limiting space, and on the other hand, it can ensure that the limiting protrusion 105 is clamped in the groove 102 .
以下将描述本申请的另一实施例,该另一实施例是在上述实施例基础上的改进,上述实施例中公开的技术内容不重复描述,上述实施例中公开的内容也属于该另一实施例公开的内容。Another embodiment of the present application will be described below. This other embodiment is an improvement on the basis of the above-mentioned embodiment. The technical content disclosed in the above-mentioned embodiment will not be described repeatedly, and the content disclosed in the above-mentioned embodiment also belongs to this other embodiment. Example disclosure.
考虑到毛细管支架100上间隔设置有多个毛细管,也就是说毛细管支架100的宽度受毛细管的个数影响,如果毛细管支架100过宽,为了保证夹持机构对毛细管支架100的稳定夹持,在该实施例中,所述夹爪104以及所述承托板106的数量可以设置有多个;多个所述夹爪104可以与多个所述承托板106一一对应,即利用多个夹爪104以及多个承托板106对毛细管支架100实现多点定位的稳定夹持。Considering that a plurality of capillaries are arranged on the capillary holder 100 at intervals, that is to say, the width of the capillary holder 100 is affected by the number of capillaries. If the capillary holder 100 is too wide, in order to ensure the stable clamping of the capillary holder 100 by the clamping mechanism, a In this embodiment, the number of the clamping jaws 104 and the supporting plate 106 can be set in multiples; the clamping jaws 104 can be in one-to-one correspondence with the supporting plates 106 , that is, using a plurality of clamping jaws 104 The clamping jaws 104 and the plurality of supporting plates 106 realize stable clamping of the capillary holder 100 with multi-point positioning.
具体地,多个所述夹爪104与多个所述承托板106沿第一方向109间隔排布,第一方向109是指毛细管支架100的宽度延伸方向。Specifically, a plurality of the clamping jaws 104 and the plurality of the supporting plates 106 are arranged at intervals along a first direction 109 , and the first direction 109 refers to the width extension direction of the capillary holder 100 .
优选地,所述夹爪104与所述承托板106的数量分别为两个,分别为第一夹爪110、第一承托板、第二夹爪111以及第二承托板,在下面的实施例同样适用。Preferably, the number of the clamping jaws 104 and the supporting plate 106 is two respectively, which are the first clamping jaw 110 , the first supporting plate, the second clamping jaw 111 and the second supporting plate, respectively. The same example applies.
以下将描述本申请的又一实施例,该又一实施例是在上述实施例基础上的改进,上述实施例中公开的技术内容不重复描述,上述实施例中公开的内容也属于该又一实施例公开的内容。Another embodiment of the present application will be described below. This further embodiment is an improvement on the basis of the above-mentioned embodiment. The technical content disclosed in the above-mentioned embodiment will not be described repeatedly, and the content disclosed in the above-mentioned embodiment also belongs to this further embodiment. Example disclosure.
在实际的实验过程中,当利用夹持机构夹持毛细管支架100后,接下来需要对毛细管支架100进行端盖103盖设的操作,以此实现毛细管支架100的密封;在实现对毛细管支架100的端盖103盖设操作时,需要驱动夹持有毛细管支架100的夹持机构沿第二方向118运动(靠近端盖103运动),从而实现对毛细管支架100的端盖103盖设操作。In the actual experimental process, after the capillary holder 100 is clamped by the clamping mechanism, the capillary holder 100 needs to be covered with the end cap 103 to seal the capillary holder 100; During the capping operation of the end cap 103, the clamping mechanism holding the capillary holder 100 needs to be driven to move in the second direction 118 (moves close to the end cap 103), so as to realize the capillary capillary holder 100 cap 103 capping operation.
基于上述问题,在该又一实施例中,所述夹持机构还可以包括第一驱动组件,所述第一驱动组件可以包括固定筒115、第一驱动件116以及丝杠117,优选地,第一驱动件116可以为第一电机,所述第一电机的输出轴与所述丝杠117连接,所述固定筒115上开设有螺纹孔,固定筒115套设于所述丝杠117上,并与所述丝杠117螺纹连接;所述固定筒115上沿第一方向109间隔设置有第一夹爪110以及第二夹爪111,第一夹爪110下方设置有第一承托板,第二夹爪111下方设置有第二承托板。Based on the above problems, in this further embodiment, the clamping mechanism may further include a first drive assembly, and the first drive assembly may include a fixed cylinder 115, a first drive member 116 and a lead screw 117, preferably, The first driving member 116 may be a first motor, the output shaft of the first motor is connected to the lead screw 117 , the fixing cylinder 115 is provided with a threaded hole, and the fixing cylinder 115 is sleeved on the lead screw 117 , and is threadedly connected with the lead screw 117; the fixing cylinder 115 is provided with a first clamping jaw 110 and a second clamping jaw 111 at intervals along the first direction 109, and a first supporting plate is arranged below the first clamping jaw 110 , a second supporting plate is arranged below the second clamping jaw 111 .
具体地,所述第一电机通过所述丝杠117能够驱动所述固定筒115沿第二方向118运动,以使所述第一夹爪110以及所述第一承托板106沿所述第二方向118运动,优选地,第二方向118是指夹持机构正常工作状态下的竖直向上或竖直向下的方向。Specifically, the first motor can drive the fixing cylinder 115 to move in the second direction 118 through the lead screw 117 , so that the first clamping jaw 110 and the first support plate 106 can move along the second direction 118 . The two directions 118 move, preferably, the second direction 118 refers to the vertical upward or vertical downward direction in the normal working state of the clamping mechanism.
更具体地,端盖103可以位于毛细管支架100的一侧,并且端盖103的高度小于毛细管支架100的高度,在实际的端盖103盖设操作中,首先夹持机构夹持毛细管支架100;然后第一电机驱动固定筒115沿竖直向下的方向运动,使得毛细管支架100底部的凹槽102插入至端盖103底部的凸起101上,最后实现毛细管支架100的端盖103盖设。More specifically, the end cap 103 can be located on one side of the capillary holder 100, and the height of the end cap 103 is smaller than the height of the capillary holder 100. In the actual capillary 103 capping operation, the clamping mechanism first clamps the capillary holder 100; Then the first motor drives the fixing cylinder 115 to move in the vertical downward direction, so that the groove 102 at the bottom of the capillary holder 100 is inserted into the protrusion 101 at the bottom of the end cap 103 , and finally the end cap 103 of the capillary holder 100 is covered.
综上,利用带有第一驱动组件的夹持机构,一方面能够实现对毛细管支架100的夹持;另一方面,能够对毛细管支架100的移动,进而实现对毛细管支架100的端盖103盖设操作。To sum up, by using the clamping mechanism with the first drive assembly, on the one hand, the capillary holder 100 can be clamped; set operation.
以下将对本申请的再一实施例进行描述,该再一实施例是在上述实施例基础上的改进,上述实施例中公开的技术内容不重复描述,上述实施例中公开的内容也属于该再一实施例公开的内容。A further embodiment of the present application will be described below. This further embodiment is an improvement on the basis of the above-mentioned embodiment. The technical content disclosed in the above-mentioned embodiment will not be described repeatedly, and the content disclosed in the above-mentioned embodiment also belongs to this further embodiment. Disclosure of an embodiment.
基于前述实施例中阐述的问题,以及考虑到对第一驱动组件的稳定固定,在该实施例中提出另一种第一驱动组件的结构,具体地,结合图3至图5所示,所述第一驱动组件可以包括固定筒115、第一驱动件116、第一支撑框架112以及设置于所述第一支撑框架112内部的第二支撑框架113,优选地,第一驱动件116可以为第一电机;所述第一驱动件116可以设置于所述第一支撑框架112的顶端,所述固定筒115的两端固定于所述第二支撑框架113上,所述第一驱动件116的输出轴通过丝杠117与所述第二支撑框架113连接,即当驱动第一电机时,通过丝杠117能够带动第二支撑框架113沿第二方向118运动,当第二支撑框架113沿第二方向118运动时候,能够使得所述固定筒115协同所述夹爪104以及所述承托板106沿第二方向118 运动,进而实现毛细管支架100的端盖103盖设。Based on the problems described in the foregoing embodiments, and considering the stable fixation of the first drive assembly, another structure of the first drive assembly is proposed in this embodiment. The first drive assembly may include a fixed cylinder 115, a first drive member 116, a first support frame 112, and a second support frame 113 disposed inside the first support frame 112. Preferably, the first drive member 116 may be The first motor; the first drive member 116 can be disposed on the top of the first support frame 112, the two ends of the fixing cylinder 115 are fixed on the second support frame 113, the first drive member 116 The output shaft is connected with the second support frame 113 through the lead screw 117, that is, when the first motor is driven, the lead screw 117 can drive the second support frame 113 to move in the second direction 118, when the second support frame 113 moves along the second direction 118 When the second direction 118 moves, the fixing cylinder 115 can cooperate with the clamping jaw 104 and the support plate 106 to move along the second direction 118 , thereby realizing the capillary 100 cap 103 being covered.
为了保证第二支撑框架113能够在第一支撑框架112上稳定运行,在该再一实施例中,所述夹持机构还可以包括辅助件125,所述辅助件125可以包括滑道126以及滑动置于所述滑道126上的滑块127;所述滑道126可以设置于所述第一支撑框架112朝向所述第二支撑框架113的端面上,所述滑块127可以设置于所述第二支撑框架113朝向所述第一支撑框架112的端面上。In order to ensure that the second support frame 113 can run stably on the first support frame 112, in this further embodiment, the clamping mechanism may further include an auxiliary member 125, and the auxiliary member 125 may include a slideway 126 and a sliding The slider 127 placed on the slideway 126; the slideway 126 can be arranged on the end surface of the first support frame 112 facing the second support frame 113, and the slider 127 can be arranged on the The second support frame 113 faces the end surface of the first support frame 112 .
具体地,借助辅助件125,所述第二支撑框架113不仅能够实现在第一支撑框架112上的稳定滑动,而且能够给予第二支撑框架113一定的导向作用。Specifically, with the aid of the auxiliary member 125 , the second support frame 113 can not only achieve stable sliding on the first support frame 112 , but also give a certain guiding effect to the second support frame 113 .
以下将对本申请的另外的实施例进行描述,该另外的实施例是在上述实施例基础上的改进,上述实施例中公开的技术内容不重复描述,上述实施例中公开的内容也属于该另外的实施例公开的内容。Additional embodiments of the present application will be described below. The additional embodiments are improvements based on the above-mentioned embodiments. The technical contents disclosed in the above-mentioned embodiments will not be described repeatedly, and the contents disclosed in the above-mentioned embodiments also belong to this additional embodiment. Examples of disclosures.
结合图6所示,毛细管支架100在实现被夹持以及端盖103盖设操作时,固定筒115在竖直方向上会受到较大的力,一旦第一电机的自锁力不足以支撑此力,固定筒115将会出现转倾斜的问题,为了克服此类问题,所述夹持机构还包括限位构件;当所述夹爪104以及所述承托板106夹持所述待夹持件时,所述限位构件能够防止所述固定筒115旋转。As shown in FIG. 6 , when the capillary holder 100 is clamped and the end cap 103 is capped, the fixing cylinder 115 will be subjected to a large force in the vertical direction, and once the self-locking force of the first motor is not enough to support the force, the fixed cylinder 115 will have a problem of turning and tilting. In order to overcome such problems, the clamping mechanism further includes a limiting member; when the clamping jaws 104 and the support plate 106 clamp the to-be-clamped When it is installed, the limiting member can prevent the fixed cylinder 115 from rotating.
具体地,所述限位构件可以为限位销129;所述限位销129可以设置于所述固定筒115的下方,所述固定筒115上对应所述限位销129的位置开设有限位孔。Specifically, the limiting member may be a limiting pin 129 ; the limiting pin 129 may be disposed below the fixing cylinder 115 , and a limiting position is provided on the fixing cylinder 115 corresponding to the limiting pin 129 hole.
在实际的使用过程中,当所述第一驱动组件驱动所述固定筒115沿所述第二方向118运动时,所述限位销129能够插设或拔出于所述限位孔。In actual use, when the first driving component drives the fixing cylinder 115 to move in the second direction 118 , the limiting pin 129 can be inserted into or pulled out of the limiting hole.
当第一电机带动固定筒115沿第二方向118下移一定距离后,限位销129能够旋转至限位孔中,此时固定筒115被限位;当夹爪104抓取毛细管支架100并完成端盖103盖设动作后,沿第二方向118上移时,限位销129离开限位孔。When the first motor drives the fixing cylinder 115 to move down a certain distance along the second direction 118, the limit pin 129 can be rotated into the limiting hole, and the fixing cylinder 115 is limited at this time; when the clamping jaw 104 grabs the capillary holder 100 and After the capping action of the end cap 103 is completed, when moving upward along the second direction 118 , the limiting pin 129 leaves the limiting hole.
以下结合图7至图9所示内容对本申请的其他实施例进行描述。在其他实施例中,当对毛细管支架100完成端盖103的盖设操作后,需要将毛细管支架100转移至PCR热循环模块(PCR热循环模块是快速分子检测的核心技术)中,以实现对毛细管支架100的热循环,为了方便将毛细管支架100转移至PCR热循环模块中,本申请还提供一种转移装置,包括第二驱动组件以及上述的夹持机构;所述第二驱动组件的输出轴与所述固定筒115连接,所述第二驱动件131能够驱动所述固定筒115旋转预设角度以使所述夹持机构将所述待夹持件从第一位置转移到第二位置。Other embodiments of the present application will be described below with reference to the contents shown in FIGS. 7 to 9 . In other embodiments, after the capillary holder 100 is capped with the end cap 103, the capillary holder 100 needs to be transferred to a PCR thermal cycling module (PCR thermal cycling module is the core technology of rapid molecular detection) to achieve Thermal cycling of the capillary holder 100, in order to facilitate the transfer of the capillary holder 100 to the PCR thermal cycling module, the present application also provides a transfer device comprising a second drive assembly and the above-mentioned clamping mechanism; the output of the second drive assembly The shaft is connected with the fixing cylinder 115, and the second driving member 131 can drive the fixing cylinder 115 to rotate by a preset angle so that the clamping mechanism transfers the to-be-clamped member from the first position to the second position .
综上,利用转移装置能够实现对毛细管支架100的转移,克服了现有技术中采用人工手持 转移的方式,一方面,提高了工作效率;另一方面,保证了毛细管支架100不被污染。To sum up, using the transfer device can realize the transfer of the capillary support 100, which overcomes the manual hand-held transfer method in the prior art, on the one hand, improves the work efficiency; on the other hand, ensures that the capillary support 100 is not polluted.
考虑到固定筒115固定在第二支撑框架113上,所述固定筒115的上部的空间有限,优选地,固定筒115在旋转的过程中,可以逆时针旋转,即第二驱动件131驱动固定筒115沿逆时针方向旋转。Considering that the fixing cylinder 115 is fixed on the second support frame 113, the space on the upper part of the fixing cylinder 115 is limited, preferably, the fixing cylinder 115 can rotate counterclockwise during the rotation process, that is, the second driving member 131 drives the fixing cylinder 115 to rotate. The barrel 115 rotates in a counterclockwise direction.
具体地,第一位置是指位于所述第二支撑框架113的一侧的试剂盒119中的毛细管支架100所在的位置,第二位置是指位于所述第二支撑框架113的另一侧的用于承托毛细管支架100的承托部所在的位置。Specifically, the first position refers to the position where the capillary holder 100 in the reagent kit 119 is located on one side of the second support frame 113 , and the second position refers to the position on the other side of the second support frame 113 . The position of the supporting portion for supporting the capillary holder 100 .
优选地,所述预设角度可以为180°。Preferably, the preset angle may be 180°.
在该实施例中,所述第二驱动组件可以包括第二驱动件131;所述第二驱动件131可以设置于所述第二支撑框架113上,所述第二驱动件131的输出轴可以穿过所述第二支撑框架113并插设至所述固定筒115的内部;优选地,所述第二驱动件131可以为第二电机。In this embodiment, the second driving assembly may include a second driving member 131; the second driving member 131 may be disposed on the second supporting frame 113, and the output shaft of the second driving member 131 may be Passing through the second support frame 113 and inserted into the interior of the fixing cylinder 115 ; preferably, the second driving member 131 may be a second motor.
具体地,当所述第二电机驱动所述输出轴旋转所述转预设角度时,能够使得所述固定筒115旋转所述预设角度。Specifically, when the second motor drives the output shaft to rotate by the predetermined angle, the fixed cylinder 115 can be rotated by the predetermined angle.
考虑到当第二电机工作时,其会产生振动,为了防止此振动传递给毛细管支架100,并对毛细管支架100产生影响,在该实施例中,所述转移构件还可以包括缓冲件132,所述缓冲件132的一端可以抵接在所述第一支撑框架112上,且另一端可以抵接在所述第二驱动件131上;优选地,所述缓冲件132可以为弹簧,利用弹簧起到减震的作用。Considering that when the second motor works, it will generate vibration, in order to prevent this vibration from being transmitted to the capillary holder 100 and affecting the capillary holder 100, in this embodiment, the transfer member may further include a buffer 132, so One end of the buffer member 132 can abut on the first support frame 112, and the other end can abut on the second driving member 131; to shock absorption.
除此之外,本申请还可以设置有支撑平台133,所述夹持机构可以设置于所述支撑平台133上。Besides, the present application may also be provided with a supporting platform 133 , and the clamping mechanism may be provided on the supporting platform 133 .
最后应说明的是:以上各实施例仅用以说明本申请的技术方案,而非对其限制;尽管参照前述各实施例对本申请进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分或者全部技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本申请各实施例技术方案的范围。此外,本领域的技术人员能够理解,尽管在此的一些实施例包括其它实施例中所包括的某些特征而不是其它特征,但是不同实施例的特征的组合意味着处于本申请的范围之内并且形成不同的实施例。Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, but not to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: The technical solutions described in the foregoing embodiments can still be modified, or some or all of the technical features thereof can be equivalently replaced; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the technical solutions of the embodiments of the present application. scope. Furthermore, those skilled in the art will appreciate that although some of the embodiments herein include certain features, but not others, included in other embodiments, that combinations of features of the different embodiments are intended to be within the scope of the present application And form different embodiments.
工业实用性Industrial Applicability
根据本申请提供的夹持机构,实现对毛细管架的夹持作用,取代了人工操作,一方面,操作简单,提高了工作效率,另一方面,保证了毛细管不受污染,保证毛细管内的提取物的纯度,保证结果的精准度。另外,根据本申请提供的转移装置能够实现对毛细管支架的转移,克服了现有技术中采用人工手持转移的方式。According to the clamping mechanism provided by the present application, the clamping effect on the capillary tube holder is realized, which replaces the manual operation. On the one hand, the operation is simple and the work efficiency is improved; The purity of the material ensures the accuracy of the results. In addition, the transfer device provided according to the present application can realize the transfer of the capillary stent, which overcomes the manual hand-held transfer method in the prior art.
此外,可以理解的是,本申请的夹持机构、转移装置等是可以重现的,并且可以应用在多 种工业应用中。例如,本申请的夹持机构可以应用于对毛细管架进行夹持。Furthermore, it will be appreciated that the gripping mechanisms, transfer devices, etc. of the present application are reproducible and can be used in a variety of industrial applications. For example, the clamping mechanism of the present application can be applied to clamp a capillary rack.

Claims (13)

  1. 一种夹持机构,用于夹持待夹持件,其特征在于,所述夹持机构包括夹爪和承托板;A clamping mechanism for clamping a to-be-clamped piece, characterized in that the clamping mechanism comprises a clamping claw and a support plate;
    所述承托板位于所述夹爪的下方,且距离所述夹爪预设距离,以使所述夹爪与所述承托板之间形成夹持空间;The supporting plate is located below the clamping jaws and is at a predetermined distance from the clamping jaws, so that a clamping space is formed between the clamping jaws and the supporting plate;
    所述夹爪的夹持端部开设有夹持槽;所述承托板上设置有限位凸起;所述夹持槽和所述限位凸起均构造成与所述待夹持件配合以实现对所述待夹持件的夹持。The clamping end of the clamping jaw is provided with a clamping groove; the support plate is provided with a limiting protrusion; both the clamping groove and the limiting protrusion are configured to cooperate with the to-be-clamped piece in order to realize the clamping of the to-be-clamped piece.
  2. 根据权利要求1所述的夹持机构,其特征在于,所述夹爪以及所述承托板的数量均为多个;The clamping mechanism according to claim 1, wherein the number of the clamping jaws and the supporting plate is multiple;
    多个所述夹爪沿第一方向间隔排布,多个所述承托板沿所述第一方向间隔排布,且多个所述夹爪与多个所述承托板一一对应设置。A plurality of the clamping claws are arranged at intervals along the first direction, a plurality of the supporting plates are arranged at intervals along the first direction, and a plurality of the clamping claws are arranged in a one-to-one correspondence with the plurality of the supporting plates .
  3. 根据权利要求1或2所述的夹持机构,其特征在于,所述待夹持件的顶端具有凸起,且所述待夹持件的的底端具有凹槽,在所述待夹持件位于所述夹持空间内,所述凸起构造成插入所述夹持槽内,并且所述限位凸起构造成卡设于所述凹槽内的情况下,所述夹持机构实现对所述待夹持件的稳定夹持。The clamping mechanism according to claim 1 or 2, wherein the top end of the to-be-clamped member has a protrusion, and the bottom end of the to-be-clamped member has a groove, and the to-be-clamped member has a groove at its bottom end. The clamping mechanism is realized when the component is located in the clamping space, the protrusion is configured to be inserted into the clamping groove, and the limiting protrusion is configured to be clamped in the groove. Stable clamping of the to-be-clamped piece.
  4. 根据权利要求1至3中的任一项所述的夹持机构,其特征在于,所述夹持机构还包括第一驱动组件,所述第一驱动组件包括固定筒、第一驱动件以及丝杠;The clamping mechanism according to any one of claims 1 to 3, characterized in that, the clamping mechanism further comprises a first driving assembly comprising a fixing cylinder, a first driving member and a wire lever;
    所述第一驱动件的输出轴与所述丝杠连接,所述丝杠与所述固定筒传动连接;The output shaft of the first driving member is connected with the lead screw, and the lead screw is in driving connection with the fixed cylinder;
    所述第一驱动件能够通过所述丝杠驱动所述固定筒沿第二方向运动,以使所述夹爪以及所述承托板沿所述第二方向运动。The first driving member can drive the fixing cylinder to move in the second direction through the lead screw, so as to make the clamping jaw and the support plate move in the second direction.
  5. 根据权利要求4所述的夹持机构,其特征在于,所述夹持机构还包括第一支撑框架以及设置于所述第一支撑框架内部的第二支撑框架;The clamping mechanism according to claim 4, wherein the clamping mechanism further comprises a first supporting frame and a second supporting frame disposed inside the first supporting frame;
    所述第一驱动件设置于所述第一支撑框架上,所述固定筒的两端固定于所述第二支撑框架上,所述第一驱动件的输出轴通过丝杠与所述第二支撑框架连接;The first driving member is arranged on the first supporting frame, the two ends of the fixing cylinder are fixed on the second supporting frame, and the output shaft of the first driving member is connected to the second supporting frame through a lead screw. support frame connection;
    所述第一驱动件能够驱动所述第二支撑框架沿第二方向运动,以使所述固定筒协同所述夹爪以及所述承托板沿第二方向运动。The first driving member is capable of driving the second supporting frame to move in a second direction, so that the fixing cylinder cooperates with the clamping jaw and the supporting plate to move in the second direction.
  6. 根据权利要求5所述的夹持机构,其特征在于,所述第一驱动组件还包括辅助件,所述辅助件包括滑道以及滑动置于所述滑道上的滑块;The clamping mechanism according to claim 5, wherein the first driving assembly further comprises an auxiliary member, and the auxiliary member comprises a slideway and a slider slidably placed on the slideway;
    所述滑道设置于所述第一支撑框架朝向所述第二支撑框架的端面上,所述滑块设置于所述第二支撑框架朝向所述第一支撑框架的端面上。The slideway is arranged on the end surface of the first support frame facing the second support frame, and the slider is arranged on the end surface of the second support frame facing the first support frame.
  7. 根据权利要求6所述的夹持机构,其特征在于,所述夹持机构还包括限位构件;The clamping mechanism according to claim 6, wherein the clamping mechanism further comprises a limiting member;
    当所述夹爪以及所述承托板夹持所述待夹持件时,所述限位构件能够防止所述固定筒 旋转。When the clamping jaw and the support plate clamp the to-be-clamped member, the limiting member can prevent the fixed cylinder from rotating.
  8. 根据权利要求7所述的夹持机构,其特征在于,所述限位构件包括限位销;The clamping mechanism according to claim 7, wherein the limiting member comprises a limiting pin;
    所述限位销设置于所述固定筒的下方,所述固定筒上对应所述限位销的位置开设有限位孔;The limiting pin is arranged below the fixing cylinder, and a limiting hole is provided on the fixing cylinder at a position corresponding to the limiting pin;
    当所述第一驱动件驱动所述固定筒沿所述第二方向运动时,所述限位销能够插设或拔出于所述限位孔。When the first driving member drives the fixing cylinder to move in the second direction, the limiting pin can be inserted into or pulled out of the limiting hole.
  9. 根据权利要求1至8中的任一项所述的夹持机构,其特征在于,所述承托板由弹簧钢形成。The clamping mechanism according to any one of claims 1 to 8, wherein the support plate is formed of spring steel.
  10. 一种转移装置,其特征在于,包括第二驱动组件以及根据权利要求5至8中的任一项所述的夹持机构;A transfer device, characterized in that it comprises a second drive assembly and the clamping mechanism according to any one of claims 5 to 8;
    所述第二驱动组件的输出轴与所述固定筒连接,所述第二驱动组件能够驱动所述固定筒旋转预设角度,以使所述夹持机构将所述待夹持件从第一位置转移到第二位置。The output shaft of the second drive assembly is connected with the fixed cylinder, and the second drive assembly can drive the fixed cylinder to rotate by a preset angle, so that the clamping mechanism can move the to-be-clamped piece from the first The position is shifted to the second position.
  11. 根据权利要求10所述的转移装置,其特征在于,所述第二驱动组件包括第二驱动件;The transfer device of claim 10, wherein the second drive assembly comprises a second drive member;
    所述第二驱动件设置于所述第二支撑框架上,所述第二驱动件的输出轴穿过所述第二支撑框架并插设至所述固定筒的内部;The second driving member is arranged on the second supporting frame, and the output shaft of the second driving member passes through the second supporting frame and is inserted into the interior of the fixing cylinder;
    当所述第二驱动件驱动所述输出轴旋转所述预设角度时,所述固定筒旋转所述预设角度。When the second driving member drives the output shaft to rotate by the predetermined angle, the fixed cylinder rotates by the predetermined angle.
  12. 根据权利要求11所述的转移装置,其特征在于,所述第二驱动件驱动所述固定筒沿逆时针方向旋转。The transfer device according to claim 11, wherein the second driving member drives the fixed cylinder to rotate in a counterclockwise direction.
  13. 根据权利要求11或12所述的转移装置,其特征在于,还包括缓冲件,所述缓冲件的一端抵接在所述第一支撑框架上,且另一端抵接在所述第二驱动件上。The transfer device according to claim 11 or 12, further comprising a buffer member, one end of the buffer member abuts on the first support frame, and the other end abuts on the second driving member superior.
PCT/CN2021/116305 2021-01-29 2021-09-02 Clamping mechanism and transfer device WO2022160717A1 (en)

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