WO2022048586A1 - 医用切割组件和减容导管系统 - Google Patents
医用切割组件和减容导管系统 Download PDFInfo
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- WO2022048586A1 WO2022048586A1 PCT/CN2021/116163 CN2021116163W WO2022048586A1 WO 2022048586 A1 WO2022048586 A1 WO 2022048586A1 CN 2021116163 W CN2021116163 W CN 2021116163W WO 2022048586 A1 WO2022048586 A1 WO 2022048586A1
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- Prior art keywords
- cutter head
- cutting assembly
- filter element
- groove
- conveying
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- 238000005520 cutting process Methods 0.000 title claims abstract description 153
- 238000011038 discontinuous diafiltration by volume reduction Methods 0.000 title claims abstract description 37
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320783—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions through side-hole, e.g. sliding or rotating cutter inside catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320758—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00681—Aspects not otherwise provided for
- A61B2017/00685—Archimedes screw
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B2017/320741—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions for stripping the intima or the internal plaque from a blood vessel, e.g. for endarterectomy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320758—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
- A61B2017/320775—Morcellators, impeller or propeller like means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/03—Automatic limiting or abutting means, e.g. for safety
- A61B2090/033—Abutting means, stops, e.g. abutting on tissue or skin
- A61B2090/034—Abutting means, stops, e.g. abutting on tissue or skin abutting on parts of the device itself
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/03—Automatic limiting or abutting means, e.g. for safety
- A61B2090/033—Abutting means, stops, e.g. abutting on tissue or skin
- A61B2090/036—Abutting means, stops, e.g. abutting on tissue or skin abutting on tissue or skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/08—Accessories or related features not otherwise provided for
- A61B2090/0801—Prevention of accidental cutting or pricking
- A61B2090/08021—Prevention of accidental cutting or pricking of the patient or his organs
Definitions
- the invention relates to the technical field of medical devices, in particular to a medical cutting assembly and a volume reduction catheter system.
- ASO arteriosclerosis obliterans
- the treatment methods for lower extremity arteriosclerosis obliterans mainly include drug therapy, surgery, endovascular therapy, compound surgery, autologous peripheral blood stem cell transplantation, and gene drug therapy.
- Endovascular treatment of lower extremity arteriosclerosis obliterans has the advantages of minimally invasive, safe, effective and quick recovery, and has become the first choice for the treatment of lower extremity arteriosclerosis obliterans.
- Current endovascular treatment methods include conventional percutaneous transluminal angioplasty (PTA) and emerging endoluminal volume reduction. Pure PTA has obvious limitations.
- the present invention provides a medical cutting assembly and a corresponding volume reduction catheter system to solve the problem that the existing intraluminal volume reduction device does not decompose the excess tissue completely enough, which leads to an unsmooth transportation process and a low overall work efficiency. question.
- a medical cutting assembly which includes a cutter head and a limiter rotatably connected with the cutter head, the cutter head includes a conveying part, the limiter includes a disassembly part, and the cutter head and the limiter During relative rotation, the disassembling part passes through the conveying part.
- the cutter head includes a cutting portion, the cutting portion includes a plurality of cutting edges extending from a proximal end to a distal end, and the conveying portion includes a conveying groove located between two adjacent cutting edges. , at least one of the cutting edges is provided with a through groove, and the through groove communicates with the conveying groove adjacent to the cutting edge. through the trough.
- the cutter head is axially limited.
- the cutting edge extends helically from the proximal end to the distal end, and the helix angle of the conveying groove gradually decreases from the distal end to the proximal end.
- the medical cutting assembly further includes a sleeve connected to the limiting member, the sleeve is sleeved on the outside of the cutter head and the limiting member, and the sleeve is At least the disintegrated portion is covered in the axial direction.
- the sleeve is provided with a plurality of decomposition grooves, and when the cutter head and the limiting member rotate relative to each other, the decomposition grooves communicate with the conveying part at least at a certain time.
- the disassembly part is located in the middle of the limiting member, and at least a part of the limiting member is sleeved on the outside of the proximal end of the cutter head.
- the axial width of the decomposed portion is smaller than the axial width of the through groove, and the axial position of the proximal end of the decomposed portion relative to the proximal end of the through groove may be tune.
- a volume-reducing conduit system comprising a continuously arranged cutting section and a conveying section
- the cutting section includes a cutting assembly
- the conveying section includes a drive shaft fixedly connected with the cutting assembly and a drive shaft sleeved on the surface of the drive shaft.
- a casing, the transmission shaft can rotate relative to the casing, the transmission shaft is provided with a conveying groove, the casing is provided with a cleaning element along the axial direction, and the transmission shaft is provided with a filter along the axial direction pieces.
- At least one cleaning part is further included, the cleaning part includes the cleaning element and a filter element located at the proximal end thereof, the filter element includes a first filter element and/or a second filter element pieces.
- the filter element includes a first filter element, and a gap is left between the outer side of the first filter element and the inner wall of the sleeve.
- the filter element includes a second filter element, and a gap is left between the inner side of the second filter element and the transmission shaft.
- the second filter element is fixed on the transmission shaft through a connecting rod, and the outer side of the second filter element is in close contact with the inner wall of the sleeve.
- the radial thickness of the filter element is less than or equal to the radial thickness of the decomposition element.
- the cleaning section includes a first cleaning section with the first filter element and a second cleaning section with the second filter element, the first cleaning section and the The second cleaning parts are arranged alternately in sequence.
- a volume-reducing conduit system comprising a continuously arranged cutting section and a conveying section
- the cutting section includes a cutting assembly
- the conveying section includes a drive shaft fixedly connected with the cutting assembly and a drive shaft sleeved on the surface of the drive shaft.
- a casing, the transmission shaft can rotate relative to the casing, a conveying groove is arranged on the transmission shaft, and a cleaning part is arranged on the inner wall of the casing, and the cleaning part includes an extension toward the transmission shaft.
- the medical cutting assembly of the present invention includes a cutter head and a limiting member connected with the cutter head, the cutter head includes a cutting portion and a conveying portion, and the limiting member includes a disassembling portion.
- the conveying part can transport the excess tissue cut by the cutter head from the distal end to the proximal end, and the limiting part is provided with a disassembling part.
- the decomposing part further cuts and decomposes the cut tissue in the conveying part into smaller volume of tissue, which is more conducive to the subsequent transport of the cut tissue.
- the volume-reducing catheter system of the present invention realizes the cutting and decomposition of the target tissue in vivo and the transport to the outside of the body, which is sufficient for tissue cutting and is more convenient for transportation, and improves the overall work efficiency.
- Fig. 1 is the overall schematic diagram of the traditional Chinese medicine cutting assembly of embodiment 1;
- Fig. 2 is the exploded schematic diagram of the traditional Chinese medicine cutting assembly of embodiment 1;
- Fig. 3 is the structural representation of cutter head in embodiment 1;
- Fig. 4 is the structural representation of the limiter in Embodiment 1;
- Fig. 5 is the working schematic diagram of the distal end of the volume reducing catheter system in Example 1;
- Fig. 6 is the working schematic diagram of the volume reduction catheter system in embodiment 1;
- Example 7 is a schematic diagram of the delivery section of the volume reduction catheter system in Example 1.
- Figure 8 is a schematic cross-sectional view of the A-A position in Figure 7;
- Fig. 9 is the working schematic diagram of the second cleaning part of the volume reducing catheter system in embodiment 1;
- Example 10 is a partial schematic view of the delivery section of another volume reduction catheter system in Example 1;
- Example 11 is a schematic structural diagram of a limiter of a medical cutting assembly in Example 2.
- Example 12 is an exploded schematic view of the medical cutting assembly in Example 3.
- Example 13 is a schematic diagram of the installation of the cutter head and the limiter in the traditional Chinese medicine cutting assembly in Example 3;
- Example 14 is a schematic structural diagram of a limiter of a medical cutting assembly in Example 3.
- Example 15 is a schematic structural diagram of the distal end of the volume reduction catheter system in Example 5.
- FIG. 16 is a schematic structural diagram of the distal end of the volume reduction catheter system in Example 6.
- FIG. 16 is a schematic structural diagram of the distal end of the volume reduction catheter system in Example 6.
- orientation or positional relationship indicated by “upper”, “lower”, “front”, “rear”, “left”, “right”, etc. is based on the drawings.
- the orientation or positional relationship is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the indicated device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention . If a feature is said to be “set”, “fixed”, “connected” to another feature, it can be directly set, fixed, or connected to another feature, or it can be indirectly set, fixed, or connected to another feature superior.
- proximal end the end of the medical device implanted in the human body or animal body that is closer to the operator
- distal end the end of the medical device implanted in the human body or animal body that is closer to the operator
- proximal end the end of the medical device implanted in the human body or animal body that is closer to the operator
- distal end the end farther from the operator
- proximal end the end of the medical device implanted in the human body or animal body that is closer to the operator
- distal end the end farther from the operator
- Embodiment 1 provides a medical cutting assembly and a corresponding volume-reducing catheter system, wherein FIGS. 1-4 correspond to the medical cutting assembly 10 , and FIGS. 5-9 correspond to the volume-reducing catheter system 11 .
- FIG. 1 is an overall schematic diagram of the traditional Chinese medicine cutting assembly in Embodiment 1
- FIG. 2 is an exploded schematic view of the traditional Chinese medical cutting assembly in Embodiment 1.
- the medical cutting assembly 10 includes a coaxially assembled cutter head 101 , a limiting member 102 and a first sleeve 103 .
- the cutter head 101 is used as the main working part for cutting and conveying excess tissue
- the limiter 102 is rotatably connected with the cutter head 101, and the limiter 102 can limit the axial position of the cutter head 101.
- the distal end of the limiting member 102 is clamped with the proximal end of the cutter head 101 and can rotate relatively.
- the limiting member 102 can further decompose the tissue delivered by the cutter head 101 .
- the first sleeve 103 is sleeved on the proximal end of the cutter head 101. On the one hand, it prevents the proximal end of the cutter head 101 from rotating to cut normal blood vessel walls or normal tissues, and on the other hand, it also limits the radial displacement of the cutter head 101, that is, The cutter head 101 is radially limited.
- the first sleeve 103 is sleeved on the outside of the cutter head 101, which not only limits the radial displacement of the cutter head 101 itself, but also when the cutter head 101 cuts and captures the narrow tissue in the blood vessel at the distal end of the cutter head 101, The cut tissue will be transported from the distal end to the proximal end of the medical cutting assembly 10 along the delivery slot 1012 , and the first sleeve 103 can also prevent the cut tissue from directly leaving the delivery slot 1012 of the cutter head 101 in the radial direction.
- the first sleeve 103 cooperates with the cutter head 101 to move the captured narrow tissue along the delivery slot 1012 toward the proximal end of the medical cutting assembly 10, so as to realize the function of cutting and transporting the tissue by the instrument.
- the first set of The tube 103 covers the proximal end portion of the cutter head 101 and the distal end portion of the stopper 102 .
- the medical cutting assembly 10 does not include the first sleeve 103, and at this time, the medical cutting assembly 10 can still have the function of cutting and decomposing tissue.
- the proximal end of the cutter head 101 in the medical cutting assembly 10 may be placed in a sheath to work, so as to collect the cut tissue by means of the sheath.
- FIG. 3 is a schematic structural diagram of the cutter head 101 in Embodiment 1
- FIG. 4 is a structural schematic diagram of the limiting member 102 in Embodiment 1.
- the proximal end of the cutter head 101 is rotatably connected to the distal end of the limiting member 102 , and the axial movement of the cutter head 101 toward the distal end is restricted by the limiting member 102 .
- the limiting member 102 is relatively fixed, and the cutter head 101 performs a rotary motion around its own rotary axis 110 to realize the rotary cutting function.
- the surface of the cutter head 101 is provided with at least two cutting edges 1011 , and the cutting edges 1011 extend from the distal end to the proximal end of the cutter head 101 and are distributed in a spiral shape.
- the cutting head 101 drives the cutting edge 1011 to rotate so as to cut the excess tissue in the blood vessel.
- the working part of the cutting edge 1011 for cutting is the distal part of the cutting edge 1011, and the proximal part of the cutting edge 1011 is sleeved with a first sleeve.
- a conveying groove 1012 extending spirally in the axial direction is provided between two adjacent cutting edges 1011 .
- the cut tissue moves along the conveying groove 1012 between the cutting edges 1011 and gradually approaches the proximal end of the medical cutting assembly 10 in the axial direction.
- the maximum outer diameter of the exposed portion of the distal end of the cutter head 101 is equal to the outer diameter of the first sleeve 103 .
- the conveying groove 1012 is a helical groove, and the angle between the tangent 130 of any point 121 on the center line 120 of the groove bottom of the conveying groove 1012 and the rotation axis 110 of the cutter head 101 is the helix angle of the conveying groove 1012 .
- the projection of the rotation axis 110 on a plane passing through the tangent line 130 and parallel to the rotation axis 110 is the projection line 111
- the angle ⁇ between the tangent line 130 and the projection line 111 is the helix angle. Due to the existence of the helix angle, when the cutter head 101 rotates, the conveying groove 1012 generates an axial component force on the captured tissue, thereby driving the captured tissue to displace in the axial direction.
- the cutter head 101 can not only cut the stenotic tissue in the blood vessel, but also make the cut tissue spirally move toward the proximal end of the medical cutting assembly 10 along the delivery slot 1012, and then reach a predetermined location.
- the helix angle of the conveying groove 1012 is gradually reduced.
- the conveying groove 1012 consists of two adjacent The cutting edge 1011 is enclosed and formed, and the helix angle of the cutting edge 1011 also changes with the change of the helix angle of the conveying groove 1012 .
- a larger helix angle is set at the distal part of the cutter edge 1011, which is beneficial for cutting and capturing tissue, and the cutting efficiency is higher; The gradual decrease facilitates the delivery of the captured tissue to the proximal end of the blade 1011 .
- the plurality of cutting edges 1011 extend linearly along the axis
- the conveying groove 1012 located between two adjacent cutting edges 1011 is a linear groove extending along the axial direction and parallel to the rotation axis 110 . Since the distal end of the cutter head 101 cuts the excess tissue, the cut tissue gradually enters the distal end of the conveying groove 1012. As the tissue in the conveying groove 1012 gradually increases, the first cut tissue is pushed to be conveyed gradually and along the groove.
- the proximal end of the trough 1012 moves, so the spiral shape of the delivery trough 1012 in Embodiment 1 is only a choice of shape to enable the delivery trough 1012 to have good delivery capacity, and the specific shape of the delivery trough 1012 may not be limited.
- the proximal end of the cutter head 101 is provided with a plurality of through grooves 1013 , and each through groove 1013 penetrates the cutting edge 1011 where it is located in the circumferential direction and communicates with the conveying groove 1012 adjacent to the cutting edge 1011 .
- the distal end of the limiting member 102 is provided with a plurality of disassembled parts 1021 at the position close to the end. , the plurality of decomposing parts 1021 are distributed at intervals along the circumferential direction of the limiting part 102 .
- the disintegrating parts 1021 enter the through groove 1013 and the conveying groove 1012 alternately, and the disassembling parts 1021 collide with the tissue in the conveying groove 1012 and decompose it into smaller volumes of tissue.
- multiple disassembling parts The 1021 moves simultaneously and alternately passes through the plurality of through grooves 1013 and the corresponding plurality of conveying grooves 1012, and the processing efficiency is high.
- the disassembled part 1021 is arranged in other shapes, including blade shape, sawtooth shape, etc., that is, the specific shape of the disassembled part 1021 in the medical cutting assembly 10 may not be limited in the corresponding embodiment of the present application.
- the disassembled part 1021 is snapped into the through groove 1013 to form a snap-fit structure, so as to realize the axial limit of the tool tip 101 without affecting the rotation of the tool tip 101 . That is to say, during the rotation of the cutter head 101, if there is no other structure for axially limiting the cutter head 101, at least a part of at least one disassembled part 1021 is always located in a through groove 1013, so as to maintain the alignment of the cutter head Axial limit of 101.
- the disassembling part 1021 only plays a disassembling function
- the limiting block 102 is additionally provided with a limiting block
- the proximal end of the cutter head 101 is also set with a positioning groove
- the limiting block is clamped with the positioning groove to realize
- the limit block does not need to engage with the conveying groove 1012, but the limit block and the positioning groove are always clamped, and the disassembled part 1021 can be completely Disengage the through slot 1013.
- the corresponding The through grooves 1013 can be arranged in one or more circumferentially, and the corresponding disassembled parts 1021 can also be arranged in one or more circumferentially.
- the disassembled part 1021 can pass through the through groove 1013 unobstructed along the circumference.
- the through groove 1013 can be provided on each cutting edge 1011.
- the distance from the bottom surface of the disassembled part 1021 to the rotating shaft 110 is greater than the distance from the outer surface of the cutting edge 1011 without the through groove 1013 to the rotating shaft 110, so as to achieve The disassembled part 1021 can pass through the through groove 1013 unobstructed along the circumference, and will not collide with the cutting edge 1011 without the through groove 1013 .
- the through-slot 1013 When there is one through-slot 1013 and one corresponding disassembled part 1012, the through-slot 1013 is set at the proximal end of the cutting edge 1011 with the largest vertical distance from the outer surface to the rotary shaft 110. During the relative rotation between the through-slot 1013 and the disassembled part 1012 , a part of the disassembled part 1012 is always located in the through groove 1013 .
- the through slot 1013 is disposed at the proximal end of the blade 1011 with the largest vertical distance from the outer surface to the rotary shaft 110 , and the through slot 1013 and the multiple disassembled parts 1012 rotate relative to each other.
- a plurality of disassembled parts 1012 alternately pass through the conveying groove 1012 and the through groove 1013 along the circumferential direction, and a part of at least one disassembled part 1012 is always located in the through groove 1013 .
- the disassembled part 1012 sequentially passes through the plurality of conveying grooves 1012 and the through grooves along the circumferential direction. 1013, and there is always at least a part of the disassembled part 1012 located in the at least one through groove 1013.
- a disassembled part 1021 is correspondingly provided on the limiting member 102 , and at this time, the disassembling part 1021 is connected with the inner wall of the limiting member 102
- the length (arc length) in the circumferential direction is greater than the width in the circumferential direction of any one of the conveying grooves 1012, so as to ensure that at least a part of at least one disintegrating piece 1021 is always located in one through groove 1013, so as to realize the disintegration of the cut tissue.
- the axial limit of the cutter head 101 is maintained.
- a plurality of through grooves 1013 may be provided on the cutter head 101 in the axial direction, and a plurality of disassembled parts 1021 may be correspondingly provided on the limiting member 102 at intervals in the axial direction.
- the plurality of disintegrating elements 1021 along the axial direction simultaneously disintegrate the tissue in the respective corresponding conveying grooves 1012 .
- at least a part of at least one disassembled part 1021 is always located in one of the through grooves 1013 to maintain the axial limit of the cutter head 101 .
- the axial widths of the plurality of disassembled parts and the axial widths of the plurality of through grooves 1013 are the same or the difference is small, so that the plurality of disassembled parts 1021 and the plurality of through grooves 1013 can be snap-connected and can be Under the premise of relative rotation, the cutter head 101 will not be displaced relative to the limiting member 102 in the axial direction.
- the axial width L1 of the plurality of disassembled parts 1021 in the entire circumferential direction is the same, and the circumferential width L2 of the corresponding plurality of through grooves 1013 is also the same in the circumferential direction.
- the axial width L1 of the disassembled part 1021 and the axial width L2 of the through groove 1013 in the tool head 101 can be set to different values, that is, the axial position of the disassembled part 1021 in the through groove 1013 can occur.
- the axial width L1 of the disassembled part 1021 is smaller than the axial width L2 of the through groove 1013, and the medical cutting assembly 10 has an axial expansion and contraction length variation (L2-L1) along the axial direction.
- the amount of protrusion of the cutter head 101 from the first sleeve 103 is changed; in the medical cutting assembly 10
- the distance between the distal end of the cutter head 101 and the limiting member 102 is changed by adjusting the axial distance of the proximal end of the disassembly member 1021 relative to the proximal end of the through groove 1013 . Axial distance of the distal end.
- the axial distance between the proximal end of the disassembly part 1021 and the proximal end of the through slot 1013 is adjusted at the distal end of the adjustment cutter head 101 .
- the medical cutting assembly 10 in this state is suitable for cutting severe, coaxial calcified lesions; when the protruding length is the smallest, the distal end of the cutter head 101 has the smallest portion for cutting, and the cutting capacity of the cutter head 101 is relatively The weakest, at this time, the proximal end of the disassembly member 1021 abuts against the proximal end of the through slot 1013 , and the medical cutting assembly 10 in this state is suitable for cutting curved and irregular lesions. Therefore, the medical cutting assembly 10 in this embodiment has good adaptability to different actual situations.
- the disintegrating element 1021 includes a side surface 1022.
- the cutter head 101 rotates to cut excess tissue in the blood vessel, the tissue chopped by the cutter head 101 reaches the position of the through groove 1013 along the conveying groove 1012.
- the limiting member 102 is relatively fixed, the cutter head 101 rotates, and the conveying slot 1012 rotates with the cutter head 101, which can not only drive the tissue in the conveying slot 1012 to rotate, but also drive the through slot 1013 to engage and separate from the disassembling piece 1021, that is, drive the disassembling
- the side 1022 of the piece 1021 continuously enters and leaves the conveying slot 1012.
- the tissue collides with the side 1022 of the disintegrating piece 1021 continuously and is cut after being dislocated, thereby being decomposed into smaller volumes of tissue, which is more conducive to subsequent tissue transportation.
- the side surface 1022 is set as a plane perpendicular to the proximal end face or the distal end face of the disassembly element 1021 .
- the side surface 1022 is provided as an inclined surface inclined to the proximal end surface or the distal end surface of the disassembly member 1021 .
- the side surface 1022 may also be non-planar, for example, the side surface 1022 may be set as an arc surface or other uniform curved surface, or a part of the side surface 1022 may be convex or concave to form an irregular surface.
- FIG. 5 is a working schematic diagram of the distal end of the volume reduction catheter system in Embodiment 1
- FIG. 6 is a working schematic diagram of the volume reduction catheter system in Embodiment 1.
- the volume reduction catheter system 11 includes the above-mentioned medical cutting assembly 10 and a control assembly 12 for controlling the action of the medical cutting assembly 10 .
- the first sleeve 103 and the limiting member 102 are welded, the distal end of the transmission shaft 1015 passes through the limiting member 102 and is connected to the cutter head 101, and the proximal end of the transmission shaft 1015 is connected to the external control assembly 12,
- the control assembly 12 controls the movement of the cutter head 101 by controlling the action of the transmission shaft 1015, so as to realize the cutting and transportation of the tissue.
- the distal part of the cutter head 101 is exposed to cut the tissue, and the first sleeve 103 covers at least the through groove 1013 of the cutter head 101 to achieve radial limitation of the cutter head 101 and fully prevent the cutter head 101 from being transported
- the tissue to be delivered moves toward the proximal end along the delivery slot 1012, and is decomposed into smaller tissues by the disintegrator 1021 when it reaches the position of the through slot 1013, and then continues to move towards the through slot 1013.
- Proximal transport as the cut tissue is again broken down into smaller tissues, facilitates rapid and efficient delivery, thereby improving cutting and delivery efficiency overall.
- the current position of the limiting member 102 is kept unchanged, and the axial position of the cutter head 101 can be adjusted by adjusting the axial position of the transmission shaft 1015 connected to the proximal end of the cutter head 101. Adjustment.
- the surface of the transmission shaft 1015 is provided with a helically extending conveying groove 1016, and the conveying groove 1016 can transport the tiny tissue after collision and disintegration by the disintegrating member 1021 to the proximal end of the transmission shaft 1015 until it is finally transported outside the body.
- a second sleeve 1017 is sleeved on the surface of the transmission shaft 1015, which plays the same protective role as the first sleeve 103. It should be understood that the first sleeve 103 and the second sleeve 1017 can be an integral structure, that is, as a A full casing comes into play.
- the second sleeve 1017 protects the blood vessel or external tissue where the transmission shaft 1015 is located;
- the second sleeve 1017 is thermally fused to the proximal end of the limiting member 102 and has an interference fit with the proximal end of the limiting member 102 .
- the control assembly 12 includes a switch group 1210, a power group 1220, a transmission group 1230 and a separation seat 1240, wherein the power group 1220 and the transmission group 1230 are rigidly connected, and the transmission group 1230 includes several transmission groups.
- a gear group is used as the transmission element, The first end of the gear set is connected to the power set 1220 , the second end is connected to the transmission shaft 1015 , and the gear set is connected to the transmission shaft 1015 in a dynamic sealing manner.
- the switch group 1210 controls the rotation of the transmission shaft 1015 through the transmission group 1230 .
- the drive shaft 1015 is mounted within the separation seat 1240 .
- the separation seat 1240 includes a first chamber 1241 and a second chamber 1242.
- the second chamber 1242 is connected to the drainage pipe 1243.
- the second sleeve 1017 is sleeved on the surface of the transmission shaft 1015.
- the cutting position of the head 101 is the cutting section
- the second sleeve 1017 and the part covered by the protective sleeve 1015 are the conveying section
- the part of the control assembly 12 is the collecting section.
- the transport section extends from the location of the cutting section cutter head 101 into the first chamber 1241 of the collection section.
- the proximal end of the second sleeve 1017 is sealed against the inner wall of the first chamber 1241, the drive shaft 1015 continues to extend to the second chamber 1242, and the delivery groove 1016 on the surface of the drive shaft 1015 also extends to the first chamber 1242.
- Two chambers 1242, and the proximal end of the transmission shaft 1015 is sealed with the inner wall of the second chamber. Therefore, the tissue cut from the position of the cutter head 101 of the cutting section will gradually enter the collection section along the conveying groove 1016. Specifically, the tissue will gradually enter the interior of the first chamber 1241, then reach the interior of the second chamber 1242, and finally With the drainage pipe 1243, it is discharged to the collection device or the outside.
- a coil spring 1018 is used to wrap around the surface of the transmission shaft 1015 to form the transport groove 1016 .
- the transmission shaft 1015 needs to be flexible in compliance with the blood vessel, and the winding spring 1018 can strengthen the supporting function of the transmission shaft 1015, that is, the supporting function of the transmission shaft can be strengthened under the premise that the transmission shaft 1015 can conform to the bending of the blood vessel;
- the winding spring 1018 has elasticity, and can play a buffering role when the cutter head 101 rotates and cuts.
- FIG. 7 is a partial schematic diagram of the conveying section of the volume reduction catheter system in Embodiment 1
- FIG. 8 is AA in FIG. 7 .
- the cross-sectional schematic diagram of the location, the first cleaning part 1023 is arranged in the conveying section, and the first cleaning part 1023 includes a number of cleaning parts 10231 (here cleaning parts 10231) protruding along the inner wall of the second sleeve 1017 in the axial direction.
- the structure of the component 10231 may be the same as that of the disassembled component in this embodiment), and the shape of the cleaning component 10231 is not limited.
- first disintegrating parts 1023 are arranged on the upper part of the conveying section in the axial direction, which can further fully decompose the tissue located in the conveying groove 1016, thereby facilitating the transportation of the cut tissue.
- first cleaning part 1023 the more cleaning elements 10231 distributed along the circumferential direction it contains, the higher the decomposition efficiency of the first cleaning part 1023.
- the winding spring 1018 is set as a segmented structure, that is, the winding spring 1018 is disconnected at the position of the first clearing part 1023, so as to ensure that the winding spring 1018 does not contact the transmission shaft 1015.
- a first filter element 1019 with a filter screen is arranged on the second sleeve 1017 at the proximal end of the first decontamination part 1023, and the tissue cut by the cutter head is directed toward the When the proximal end is transported, it is easy to move against the protrusion of the first cleaning part 1023 without colliding with the first cleaning part 1023, thus causing the problem of insufficient decomposition. Therefore, a supplementary setting is provided near the cleaning part 1024.
- the first filter element 1019 that is, the cleaning part 1023 includes a cleaning element 10231 and a first filter element 1019 located at the proximal end of the cleaning element 10231 .
- the first filter element 1019 is fixed on the transmission shaft 1015 and moves together with the transmission shaft 1015 . If the first filter element 1019 is disposed at the distal end of the first decontamination part 1023 , the tissue cannot reach the position of the first decontamination part 1023 . Therefore, the first filter element 1019 is disposed on the proximal side of the first decontamination part 1023 , preferably, the distal end face of the first filter element 1019 is in contact with the proximal end face of the first decontamination part 1023, or the distance from the distal end face of the first filter element 1019 to the proximal end face of the first decontamination part 1023 is 0.1 to 5mm.
- the specific work is as follows:
- the transmission shaft 1015 rotates at high speed relative to the second casing 1017, the cleaning element 10231 is located on the inner wall of the second casing 1017, the first filter element 1019 is fixed on the transmission shaft 1015 and is located on the proximal side of the cleaning element 10231, There is a gap between the outer side of the first filter element 1019 and the second sleeve 1017 to avoid excessive tissue accumulation on the surface of the first filter element 1019 .
- the first filter element 1019 rotates relative to the cleaning element 10231 along with the drive shaft 1015, a part of the tissue reaching the position of the first cleaning part 1023 is further cleaned by the cleaning element 1024, and the other part of the tissue is adhered to the cleaning element 10231.
- part of the tissue that was not cleaned up was captured by the first filter element 1019, while the cleaning element 1024 passed through the surface of the first filter element 1019, and the side and bottom surfaces of the cleaning element 10231
- the tissue captured by the first filter element 1019 is collided and decomposed, so as to achieve further decomposition, so that the decontamination effect of the first decontamination unit 1023 is better.
- FIG. Clearance Department 1025 is a working schematic diagram of the second cleaning part 1025 in Embodiment 1 of the present invention.
- the second cleaning part 1025 includes a cleaning part 10241 and a second filter part 1020.
- the structure of the second filter part 1020 is different from that of the first filter part.
- the second filter element 1020 is fixed on the transmission shaft 1015 through several connecting rods 1021. It is worth noting that the screen part of the second filter element 1020 is in close contact with the inner wall of the second sleeve 1017, that is, from the first Tissue escaping from the gap 1010 of a filter element 1019 will be captured by the second filter element 1020 and then cleaned up by the cleaning element 10241 . There is a gap between the inner side of the surface filter screen of the second filter element 1020 and the transmission shaft 1015, which can not only prevent tissue from accumulating on the surface of the filter screen, but also prevent the filter screen from being too large and affecting the liquid flow.
- the radial thickness of the second filter element 1020 is less than or equal to the radial thickness of the cleaning element 10241, and the cleaning element 10241 can cover the entire surface of the second filter element 1020, so as to fully decompose the tissue.
- first cleaning unit 1023 and the second cleaning unit 1024 may not be limited, that is, a plurality of first cleaning units 1023 and second cleaning units 1024 may be provided, but preferably Therefore, at least for the filter element located farthest from the proximal end, the distal end of the filter element is provided with at least one cleaning element.
- the winding spring 1018 still adopts a continuous structure, and a gap is left between the protrusion of the first clearing part 1023 and the winding spring 1018 .
- FIG. 10 is a partial schematic view of the conveying section of another volume reduction catheter system in Embodiment 1 of the present invention.
- the side wall 2027 of the groove 2016 spirally extends along the transmission shaft 2015.
- a corresponding position of the side wall 2027 of the transmission shaft 1015 is provided with an avoidance groove 2028 to avoid the cleaning member 2023, and the avoidance groove 2028 penetrates the side wall.
- the avoidance groove 2028 of the conveying groove 2016 and the cleaning member 2023 overlap in the radial direction, the avoidance groove 2028 accommodates the cleaning member 2023, thereby preventing the cleaning member 2023 and the side wall 2027 of the conveying groove 2016 from occurring. collision.
- the cutter head 101 of the volume reducing catheter system is driven by the drive shaft 1015, and the second sleeve 1017 covers a portion of the proximal end of the cutter head 101 (that is, the second sleeve 1017 extends to the cutter head instead of the stopper) 101 position), the second sleeve 1017 of the volume reduction catheter system is provided with a plurality of clearing parts along the axial direction, and at least one clearing part is located at the proximal end of the cutter head 101 .
- FIG. 11 is a schematic structural diagram of the upper limit piece of the medical cutting assembly in the volume reduction catheter system of the second embodiment.
- the limiting member is rigidly connected with the first sleeve, that is, the limiting member and the first sleeve function as a whole, and the limiting member and the first sleeve can be welded, integrally formed, or the like.
- the structure of the limiter can also be changed, and a part of the limiter can be used to replace the function of the first sleeve.
- the disassembling member 2021 is arranged on the inner wall of the middle portion of the limiting member 202 .
- a part of the distal tube wall of the limiting member 202 is sleeved at least outside the proximal end of the cutter head.
- a part of the distal tube wall of the limiting member 202 plays the same role as the first sleeve in the previous embodiment 1.
- the limiting member 202 in Embodiment 2 is structurally changed compared to the limiting member in Embodiment 1, so that the design of the first sleeve is omitted, the production efficiency is improved and the process cost is reduced. Processing problems such as whether the connection strength between the casing and the limiter is sufficient and whether the sealing is good.
- first sleeve refers to a part of the distal wall of the limiting member 202 that has the same function as the first sleeve in this embodiment.
- Example 3 the connection method between the cutter head and the stopper is different from that in Example 1, the setting of the sleeve is the same as that in Example 1, and the volume reduction catheter system and medical cutting assembly in Example 3 are the same as those in Example 1. The same parts of the catheter system and the medical cutting assembly will not be repeated here.
- Figure 12 is an exploded schematic diagram of the traditional Chinese medicine cutting assembly in Example 3
- Figure 13 is a schematic diagram of the installation of the cutter head and the limiter in the traditional Chinese medicine cutting assembly in Example 3
- Figure 14 is the traditional Chinese medicine in Example 3.
- the medical cutting assembly 30 includes a coaxially assembled cutter head 301 , a limiting member 302 and a first sleeve 303 . It should be clear that, except that the connection position structure of the cutter head 301 and the limiting member 302 is changed, the other structures, functions and related expansion schemes unrelated to the connection position structure in Embodiment 3 continue to use the content in Embodiment 1.
- a conveying groove 3012 is formed between two adjacent cutting edges 3011, and the proximal end of the cutting head 301 is also provided with a plurality of through grooves 3013, and each through groove 3013 penetrates the cutting edge 3011 where it is located in the circumferential direction and communicates with the cutting edge.
- the through groove 3013 is located inside the proximal end of the knife edge 3011, the bottom surface 30131 of the through groove 3013 forms a stepped surface with the inner wall surface 30111 of the proximal end of the knife edge 3011, and the distance 30131 from the bottom surface of the through groove 3013
- the distance from the axis of rotation of the cutter head 301 is greater than the distance from the inner wall surface 30111 of the proximal end of the cutting edge 3011 to the axis of the axis of rotation of the cutter head 301 .
- the limiting member 302 includes a disassembling part 3021 and a connecting part 3022 .
- the disassembling part 3021 is disposed at a position near the end of the distal end of the connecting part 3022 , and the disassembling part 3021 protrudes outward from the outer wall of the connecting part 3022 .
- the distance from the top surface 30211 of the disassembled part 3021 to the axis of the rotary shaft of the stopper 302 is less than or equal to the distance from the bottom surface 30131 of the through groove 3013 to the axis of the rotary axis of the cutter head 301;
- the distance from the inner wall surface 30111 of the proximal end of the cutting edge 3011 to the axis of rotation of the cutter head 301 is greater than or equal to the distance from the surface 30221 of the connecting portion 3022 to the axis of the rotation axis of the stopper 302 . Since the cutter head 301 and the limiting member 302 are coaxially disposed, the axis of the rotary shaft of the cutter head 301 and the axis of the rotary shaft of the limiting member 302 are the same straight line.
- the disintegrating parts 3021 enter the through groove 3013 and the conveying groove 1012 alternately, and the disassembling parts 3021 collide with the tissue in the conveying groove 3012 and disintegrate the tissue into smaller volumes.
- the distance from the top surface 30211 of the decomposition part 3021 to the axis of the rotation axis of the limiting part 302 is greater than or equal to the distance from the inner wall surface 30111 of the proximal end of the cutting edge 3011 to the cutting head 301 Distance from the axis of the rotary axis.
- a channel 3023 extending from the proximal end to the distal end of the limiting member 302 is provided in the central part of the limiting member 302 to facilitate the insertion of the drive shaft.
- the tissue is delivered through a delivery cavity inside the cutter head
- the delivery cavity is a cavity provided inside the cutter head
- the delivery cavity includes an input port at the distal end of the cutter head and an output at the proximal end of the cutter head
- the output port is close to the through groove, and the tissue cut by the distal end of the cutter head enters the delivery cavity from the input port, leaves the delivery cavity from the output port, and collides with the disassembled part structure when it reaches the through groove position to be further decomposed.
- a delivery slot structure as in Example 1 can be provided inside the delivery cavity to facilitate the transport of tissue.
- a decomposition groove can be provided on the inner wall of the sleeve (including the first sleeve and the second sleeve), and when the cutter head and the sleeve rotate relative to each other, The excess tissue transported in the conveying tank collides with the side wall of the decomposition tank to achieve further decomposition, and the larger the side wall area of the decomposition tank, the higher the decomposition efficiency.
- the tube wall of the cannula forms a window, the decomposition efficiency of the entire medical cutting assembly is improved the most.
- FIG. 15 is a schematic structural diagram of the distal end of the volume reduction catheter system in Example 5, the volume reduction catheter system and medical cutting assembly in Example 4 and the volume reduction catheter system and medical cutting components in Examples 1-4. The same parts of the components will not be repeated here.
- the main improvement point of Example 4 is that a decomposition slot is added on the first sleeve 403 of the medical cutting assembly in Example 4, and the decomposition slot needs to be the same as the delivery slot (or delivery cavity). It is connected at least at a certain time, so that the tissue in the delivery groove (or the delivery cavity) can enter the decomposition groove and collide with the inner wall of the decomposition groove to achieve further decomposition.
- Example 4 The decomposition groove in the first casing 403 penetrates through the wall of the first sleeve 403 to form a first window 4031 .
- the first window 4031 can improve the decomposition efficiency of the window position to a certain extent. Specifically, when the cutter head 401 rotates at a high speed, a part of the cut tissue in the conveying groove (or conveying cavity) will collide with the side wall of the first window 4031, thereby being further decomposed.
- first window 4031 is relatively small relative to the entire surface of the first sleeve 403, and the gap between the outer surface of the first sleeve 403 and the inner wall of the blood vessel is small, when the cutter head 401 rotates at a high speed, there is almost no material to be transported to the proximal end. Tissue will exit the medical cutting assembly from the first window 4031.
- the setting of the first window 4031 satisfies that at least one decomposition element is located between the distal end and the proximal end of the first window 4031 in the axial direction.
- the reason is that the relative rotation of the cutter head and the limiting member in the medical cutting assembly drives the relative rotation of the conveying groove and the disassembled part, and the disintegrating part collides with the excess tissue in the conveying groove in the circumferential direction, resulting in the excess tissue in the conveying groove being destroyed.
- the impact displacement and transmission are further decomposed, and a part of the excess tissue displaced by the impact hits the inner wall of the first window 4031 again, resulting in further decomposition. That is to say, when the decomposed piece passes through the conveying slot, it drives the excess tissue in the conveying slot. It collides with the side wall of the first window 4031, so that the decomposition effect of the first window 4031 at this position is the best.
- FIG. 16 is a schematic structural diagram of the distal end of the volume reduction catheter system in Example 6.
- the volume-reduced catheter system and medical cutting assembly of Example 6 are improved based on Example 5, and the same parts of the volume-reduced catheter system and medical cutting assembly of Example 6 as the volume-reduced catheter system and medical cutting assembly of Example 5 are omitted here.
- the main difference between the two is that, on the basis of the embodiment 5, the TCM cutting assembly in Example 3 adds a new decomposition groove.
- the decomposition groove penetrates the pipe wall of the first sleeve 503, forming a The second window 5032, the original first window is located on the back of the second window 5032, so it is not shown.
- the second window 5032 is located at the distal end of the first sleeve 503.
- the cut tissues inside the distal end of 503 collide, and these tissues are further decomposed into smaller tissues, which improves the decomposing efficiency of the medical cutting assembly at the distal end of the first cannula 503 .
- Embodiment 6 is an improvement based on the design of a single decomposition groove in Embodiment 5, that is, in Embodiment 6, a decomposition groove is added at a position different from the decomposition groove in The decomposition efficiency is improved, thereby improving the overall decomposition efficiency of the medical cutting assembly. Therefore, based on this idea, the embodiment in which a plurality of decomposition grooves are arranged on the limiting member should be regarded as an embodiment equivalent to the embodiment 5 or 6.
- the specific shape and number of decomposition grooves are not limited. In order to obtain a better decomposition effect, at least one decomposition The member is located between the proximal end portion and the distal end portion of one of the decomposition grooves along the axial direction of the limiting member.
- the decomposition tank can also be used in the transport section.
- the difference from Embodiments 5-6 is that in order to ensure the reliable transportation of the cut tissue in the transport section, the decomposition tank cannot penetrate through the second sleeve of the transport section. outer wall.
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Abstract
一种医用切割组件(10)和减容导管系统,医用切割组件(10)包括刀头(101)和与刀头(101)连接的限位件(102),刀头(101)包括输送部(1012),限位件(102)包括分解部(1021),刀头(101)和限位件(102)相对转动时,分解部(1021)穿过输送部(1012)。减容导管系统包括切割段和运送段。输送部(1012)能够将被刀头(101)切割的多余组织从远端运往近端,而限位件(102)上设有分解部(1021),在刀头(101)与限位件(102)发生相对旋转时,分解部(1021)穿过输送部(1012),高速旋转的分解部(1021)将输送部(1012)内的切割下来的组织进一步切割分解为更小体积的组织,使其分解更加充分,更有利于多余组织后续的运出。
Description
本发明涉及医疗器械技术领域,尤其是涉及一种医用切割组件和减容导管系统。
下肢动脉硬化闭塞症(arteriosclerosis obliterans,ASO)是中、老年人的常见病、多发病,也是动脉粥样硬化在下肢的重要表现。
目前对下肢动脉硬化闭塞症的治疗方法主要包括药物治疗、外科手术、腔内治疗、复合手术和自体外周血干细胞移植、基因药物治疗等。下肢动脉硬化闭塞症的腔内治疗具有微创、安全、有效、恢复快等优点,已成为下肢动脉硬化闭塞症治疗的首选。目前腔内治疗方法包括常规的经皮腔内血管成形术(percutaneous transluminal angioplasty,PTA)和新兴的腔内减容术。单纯的PTA具有明显的局限性,单纯的对狭窄段做扩张处理,无法祛除多余组织,且不可避免对血管壁进行拉伸,易产生气压伤及夹层,术后容易回弹而呈现再狭窄状态。所以PTA通常与腔内减容术联用,其中,经腔内减容术中的皮腔内机械性斑块切除术可切除斑块,配合PTA可以达到良好的治疗效果。然而现有的腔内减容术在切除多余组织后,对于切下来的多余组织不做处理,被切割下来的多余组织保持原状进行运出,对多余组织的分解不够彻底,多余组织的运输过程不流畅,整体工作效率低。
发明内容
为此,本发明提供一种医用切割组件和对应的减容导管系统,以解决现有的腔内减容装置对多余组织的分解不够彻底,进而导致运输过程不流畅、整体工作效率较低的问题。
本发明所采用的技术方案是:
提供一种医用切割组件,包括刀头和与所述刀头转动连接的限位件,所述刀头包括输送部,所述限位件包括分解部,所述刀头与所述限位件相对转动时,所述分解部穿过所述输送部。
在其中一个实施例中,所述刀头包括切割部,所述切割部包括从近端到远端延伸的多个刀刃,所述输送部包括位于相邻两个所述刀刃之间的输送槽,至少一个所述刀刃上设有通槽,所述通槽和与所述刀刃相邻的所述输送槽连通,所述刀头与所述限位件相对转动时,所述分解部多次穿过所述输送槽。
在其中一个实施例中,所述分解部有一个或多个,所述刀头在转动的过程中,始终有至少一个所述分解部的至少一部分位于一个所述通槽内,以对所述刀头进行轴向限位。
在其中一个实施例中,所述分解部有多个,至少两个所述分解部沿所述限位件的周向方 向或轴向方向间隔设置。
在其中一个实施例中,所述刀刃从近端到远端呈螺旋状延伸,所述输送槽的螺旋角从远端至近端逐渐减小。
在其中一个实施例中,所述医用切割组件还包括与所述限位件连接的套管,所述套管套设在所述刀头和所述限位件的外部,且所述套管在轴向上至少覆盖所述分解部。
在其中一个实施例中,所述套管上设有若干分解槽,所述刀头与所述限位件相对转动时,所述分解槽与所述输送部至少在某一时刻连通。
在其中一个实施例中,所述分解部位于所述限位件的中部,且所述限位件的一部分至少套设在所述刀头的近端的外部。
在其中一个实施例中,所述分解部的轴向宽度小于所述通槽的轴向宽度,所述分解部的近端端部相对于所述通槽的近端端部的轴向位置可调。
还提供一种减容导管系统,包括连续设置的切割段和运送段,所述切割段包括切割组件,所述运送段包括与切割组件固定连接的传动轴和套设在所述传动轴表面的套管,所述传动轴能与所述套管发生相对转动,所述传动轴上设有运送槽,所述套管沿轴向设有清解件,所述传动轴沿轴向设有过滤件。
在其中一个实施例中,所述清解件为多个,所述过滤件为多个,至少一个所述清解件位于全部所述过滤件的远端。
在其中一个实施例中,还包括至少一个清解部,所述清解部包括所述清解件与位于其近端的过滤件,所述过滤件包括第一过滤件和/或第二过滤件。
在其中一个实施例中,所述过滤件包括第一过滤件,所述第一过滤件的外侧与所述套管的内壁间留有间隙。
在其中一个实施例中,所述过滤件包括第二过滤件,所述第二过滤件的内侧与所述传动轴间留有间隙。
在其中一个实施例中,所述第二过滤件通过连杆固定在所述传动轴上,所述第二过滤件的外侧贴紧所述套管的内壁。
在其中一个实施例中,所述过滤件的径向厚度小于或等于所述分解件的径向厚度。
在其中一个实施例中,所述清解部包括具有所述第一过滤件的第一清解部和具有所述第二过滤件的第二清解部,所述第一清解部和所述第二清解部依次交替排列。
还提供一种减容导管系统,包括连续设置的切割段和运送段,所述切割段包括切割组件,所述运送段包括与切割组件固定连接的传动轴和套设在所述传动轴表面的套管,所述传动轴能与所述套管发生相对转动,所述传动轴上设有运送槽,所述套管内壁设有清解部,所述清解部包括朝向所述传动轴延伸的分解件。
本发明实施例的有益效果:
本发明的医用切割组件,包括刀头和与刀头连接的限位件,刀头包括切割部和输送部, 限位件包括分解部,刀头与限位件相对转动时,分解部穿过输送部。输送部能够将被刀头切割的多余组织从远端运往近端,而限位件上设有分解部,在刀头与限位件发生相对旋转时,分解部穿过输送部,高速旋转的分解部将输送部内的切割下来的组织进一步切割分解为更小体积的组织,更有利于切割下来的组织后续的运出。本发明的减容导管系统实现体内目标组织的切割和分解以及运输至体外,对组织切割充分且更利于输送,实现了整体上的工作效率的提高。
图1是实施例1中医用切割组件的整体示意图;
图2是实施例1中医用切割组件的爆炸示意图;
图3是实施例1中刀头的结构示意图;
图4是实施例1中限位件的结构示意图;
图5是实施例1中减容导管系统远端的工作示意图;
图6是实施例1中减容导管系统的工作示意图;
图7是实施例1中减容导管系统的运送段的示意图;
图8是图7中A-A位置的横截面示意图;
图9是实施例1中的减容导管系统的第二清解部的工作示意图;
图10是实施例1中另一种减容导管系统的运送段的部分示意图;
图11是实施例2中医用切割组件的限位件的结构示意图;
图12是实施例3中医用切割组件的爆炸示意图;
图13是实施例3中医用切割组件中刀头和限位件的安装示意图;
图14是实施例3中医用切割组件的限位件的结构示意图;
图15是实施例5中减容导管系统远端的结构示意图;
图16是实施例6中减容导管系统远端的结构示意图。
为了便于理解本发明,下面将参照相关附图对本发明进行更全面的描述。附图中给出了本发明的较佳的实施例。但是,本发明可以以许多不同的形式来实现,并不限于本文所描述的实施例。相反地,提供这些实施例的目的是使对本发明的公开内容的理解更加透彻全面。
在本发明的描述中,如果涉及到方位描述,例如“上”、“下”、“前”、“后”、“左”、“右”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本发明的限制。如果某一特征被称为“设置”、“固定”、“连接”在另一个特征,它可以直接设置、固定、连接在另一个特征上,也可以间接地设置、固定、连接在另一个特征上。
在本发明实施例的描述中,如果涉及到“若干”,其含义是一个以上,如果涉及到“多 个”,其含义是两个以上,如果涉及到“大于”、“小于”、“超过”,均应理解为不包括本数,如果涉及到“以上”、“以下”、“以内”,均应理解为包括本数。如果涉及到“第一”、“第二”,应当理解为用于区分技术特征,而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量或者隐含指明所指示的技术特征的先后关系。
此外,除非另有定义,本发明实施例所使用的技术术语和科学术语均与所属技术领域的技术人员通常理解的含义相同。本文中在本发明的说明书中所使用的术语只是为了描述具体的实施例的目的,不是旨在于限制本发明。本文所使用的术语“及/或”包括一个或多个相关的所列项目的任意的和所有的组合。
需要说明的是,在介入医疗器械领域,一般将植入人体或动物体内的医疗器械的距离操作者较近的一端称为“近端”,将距离操作者较远的一端称为“远端”,并依据此原理定义医疗器械的任一部件的“近端”和“远端”。“轴向”一般是指医疗器械在被输送时的长度方向,“径向”一般是指医疗器械的与其“轴向”垂直的方向,并依据此原理定义医疗器械的任一部件的“轴向”和“径向”。
实施例1
实施例1提供了一种医用切割组件和对应的减容导管系统,其中附图1-4对应医用切割组件10,附图5-9对应减容导管系统11。
参照图1-2,图1是实施例1中医用切割组件的整体示意图,图2是实施例1中医用切割组件的爆炸示意图。在此实施例中,医用切割组件10包括同轴装配的刀头101、限位件102以及第一套管103。其中,刀头101作为实现切割和输送多余组织的主要工作部件,限位件102与刀头101转动连接,且限位件102能对刀头101进行轴向限位,在本实施例中,限位件102的远端与刀头101的近端卡接并能相对转动,此外,限位件102还能对刀头101输送的组织进行再次分解。第一套管103套设在刀头101的近端,一方面是避免刀头101的近端旋转切割正常血管壁或正常组织,另一方面也限制了刀头101沿径向的位移,即对刀头101进行径向限位。
第一套管103套设在刀头101的外部,不仅限制了刀头101自身沿径向的位移,同时当刀头101将位于刀头101远端的血管中的狭窄组织切割并捕获后,切割下来的组织会沿着输送槽1012从医用切割组件10的远端向近端运输,第一套管103还能防止切割下来的组织直接沿径向离开刀头101的输送槽1012。也就是说,第一套管103配合刀头101使被捕获的狭窄组织沿输送槽1012朝向医用切割组件10的近端运动,实现器械对组织的切割和运出功能,具体的,第一套管103覆盖刀头101的近端部分和限位件102的远端部分。
在另一实施例中,医用切割组件10不包括第一套管103,此时医用切割组件10仍能具备切割和分解组织的功能。
在另一实施例中,可以将医用切割组件10中刀头101的近端置于鞘管内工作,以借助鞘管收集切割后的组织。
结合图3、图4共同说明,图3是实施例1中刀头101的结构示意图,图4是实施例1中限位件102的结构示意图。具体的,刀头101的近端与限位件102的远端转动连接,且刀头101被限位件102限定了朝向远端的轴向移动。在实际工作时,限位件102相对固定,刀头101绕其自身的回转轴110做回转运动以实现旋切功能。刀头101表面设有至少两条刀刃1011,刀刃1011从刀头101的远端延伸至近端且呈螺旋状分布。刀头101带动刀刃1011旋转从而实现对血管中多余组织的切割,实际上,刀刃1011实现切割的工作部位为刀刃1011的远端部分,刀刃1011的近端部分所在位置套设有第一套管103,以限制刀刃1011的径向位移以及保护刀刃1011的近端部分所在位置处的血管或组织被刀刃1011的近端部分割伤。相邻的两个刀刃1011间设有沿轴向螺旋延伸的一个输送槽1012。随着刀头101的绕自身回转轴110的转动,被切割的组织沿着刀刃1011间的输送槽1012运动,在轴向上逐渐靠近医用切割组件10的近端。为了获得更大的切割面积,刀头101的远端的裸露部分的最大外径与第一套管103的外径相等。
输送槽1012为螺旋形态的槽,输送槽1012的槽底中心线120上任一点121的切线130与刀头101的回转轴110的夹角即为输送槽1012的螺旋角。在图3中,回转轴110在通过切线130且与回转轴110平行的平面上的投影为投影线111,则切线130与投影线111的夹角α即为螺旋角。由于螺旋角存在,在刀头101旋转时,输送槽1012对被捕获的组织产生一个轴向的分力,从而带动被捕获的组织沿轴向位移。使刀头101不仅可以切割血管中的狭窄组织,还能使已切割的组织朝着医用切割组件10的近端沿着输送槽1012进行螺旋运动,进而到达预定地点。
在另一实施例中,为了获得更好的输送效果,从刀头101的远端至其近端,输送槽1012的螺旋角逐渐减小,相应的,由于输送槽1012由相邻的两个刀刃1011围合形成,刀刃1011的螺旋角也随着输送槽1012的螺旋角变化而变化。对于刀头101整体而言,在刀刃1011的远端部分设置较大的螺旋角,有利于切割捕获组织,切割效率较高;随着输送槽1012向近端的延伸,输送槽1012的螺旋角逐渐减小,有利于被捕获的组织向刀刃1011的近端的输送。
在另一实施例中,多个刀刃1011沿轴直线延伸,位于相邻的两个刀刃1011间的输送槽1012为沿轴向延伸且平行于回转轴110的直线槽。由于刀头101的远端对多余组织进行切割,切割下来的组织逐渐进入输送槽1012的远端,随着输送槽1012槽内的组织逐渐增多,推动先切割下来的组织逐渐并沿槽朝向输送槽1012的近端运动,因此输送槽1012在实施例1中设置为螺旋形态只是使输送槽1012拥有良好输送能力的一种形状的选择,输送槽1012的具体形状可以不做限定。
在实施例1中,刀头101的近端设有多个通槽1013,每个通槽1013沿周向贯通其所在的刀刃1011并连通与该刀刃1011相邻的输送槽1012。如图4所示,限位件102的远端靠近端部的位置处设有多个分解件1021,分解件1021设置为凸台形状,分解件1021从限位件102的内壁向内凸出,多个分解件1021沿限位件102的周向间隔分布。刀头101在转动时,分解件1021交替地进入通槽1013和输送槽1012,分解件1021碰撞输送槽1012内的组织并 将其分解为更小体积的组织,本实施例中多个分解件1021同时运动,分别交替穿过多个通槽1013和对应的多个输送槽1012,加工效率较高。
在另一实施例中,分解件1021设置为其它形状,包括设置为叶片状、锯齿状等,也即本申请对应实施例对医用切割组件10中分解件1021的具体形状可以不做限制。
此外,分解件1021卡入通槽1013中形成卡接结构,在不影响刀头101旋转的前提下,实现对刀头101的轴向限位。也就是说,在刀头101的转动过程中,如果没有其他结构对刀头101进行轴向限位,则始终有至少一个分解件1021的至少一部分位于一个通槽1013中,以维持对刀头101的轴向限位。
在另一实施例中,分解件1021只起到分解作用,限位件102上另设限位块,刀头101的近端也另设定位槽,限位块与定位槽卡接以实现对刀头101的轴向限位,刀头101与限位件102发生相对旋转时,限位块无需与输送槽1012发生交合,但是限位块与定位槽始终卡接,分解件1021可以完全脱离通槽1013。
在另一实施例中,当刀头101上的多个刀刃1011的外表面到回转轴110的垂直距离不同(即刀刃1011的高度不同)时,在刀头101的某一轴向位置,对应的通槽1013可以沿周向设置为一个或多个,对应的分解件1021也可以沿周向设置为一个或多个。在刀头101与限位槽102发生相对旋转时,分解件1021沿圆周不受阻碍地穿过通槽1013,通常来说,在每个刀刃1011上均设置通槽1013即可,在特殊情况下,即只有一部分刀刃1011上设置通槽1013的情况下,需要满足:分解件1021的底面到回转轴110的距离大于未设置通槽1013的刀刃1011外表面到回转轴110的距离,以实现分解件1021能沿圆周不受阻碍地穿过通槽1013,且不会碰撞未设置通槽1013的刀刃1011。
当通槽1013为一个,对应的分解件1012为一个时,通槽1013设置在外表面到回转轴110的垂直距离最大的刀刃1011的近端,通槽1013与分解件1012发生相对旋转的过程中,分解件1012的一部分始终位于通槽1013中。
当通槽1013为一个,对应的分解件1012为多个时,通槽1013设置在外表面到回转轴110的垂直距离最大的刀刃1011的近端,通槽1013与多个分解件1012发生相对旋转的过程中,多个分解件1012依次交替通过沿周向的输送槽1012和通槽1013,且始终有至少一个分解件1012的一部分位于通槽1013内。
当通槽1013为多个,对应的分解件1012为一个时,多个通槽1013与分解件1012发生相对旋转的过程中,分解件1012依次通过沿周向的多个输送槽1012和通槽1013,且始终有分解件1012的至少一部分位于至少一个通槽1013内。
在另一实施例中,刀头101上沿周向设置一个或者多个通槽1013时,限位件102上对应设置一个分解件1021,此时分解件1021与限位件102的内壁连接处沿周向的长度(弧长)大于任意一个输送槽1012的沿周向的宽度,从而保证始终有至少一个分解件1021的至少一部分位于一个通槽1013中,以实现对被切割组织的分解的同时,维持对刀头101的轴向限位。
在另一实施例中,刀头101上可以沿轴向设置多个通槽1013,对应的在限位件102上沿轴向间隔设置多个分解件1021。刀头101转动时,沿轴向的多个分解件1021同时对各自对应的输送槽1012内的组织进行分解。同样的,始终有至少一个分解件1021的至少一部分位于一个通槽1013中,以维持对刀头101的轴向限位。
在实施例1中,多个分解件的轴向宽度和多个通槽1013的轴向宽度相等或差值较小,在满足多个分解件1021与多个通槽1013能实现卡接且能发生相对旋转的前提下,刀头101相对于限位件102在轴向上不会发生位移,进一步地,为了使多个分解件1021和多个通槽1013间的相对转动过渡平顺且不会发生干涉,多个分解件1021在整个圆周方向的轴向宽度L1均相同,对应的多个通槽1013在圆周方向上周向宽度L2也相同。
在另一实施例中,分解件1021的轴向宽度L1与刀头101中通槽1013的轴向宽度L2可设置为不同的值,即分解件1021在通槽1013内的轴向位置可以发生变化,分解件1021的轴向宽度L1小于通槽1013的轴向宽度L2,医用切割组件10具有沿轴向的轴向伸缩长度变化量(L2-L1)。通过调整分解件1021的近端端部相对于通槽1013的近端端部的轴向距离,也就是改变了刀头101从第一套管103伸出的伸出量;在医用切割组件10不包括第一套管103时,通过调整分解件1021的近端端部相对于通槽1013的近端端部的轴向距离,改变了刀头101的远端端部到限位件102的远端端部的轴向距离。实质上,不管医用切割组件10是否包括第一套管103,其调整分解件1021的近端端部相对于通槽1013的近端端部的轴向距离都是在调整刀头101的远端端部到限位件102的远端端部的轴向距离。因此,刀头101相对于限位件102或第一套管103具有至少两种不同的伸出长度。当伸出长度最大时,刀头101的远端的用于切割的部分最大,刀头101的切割能力最强,此时分解件1021的远端端部抵持通槽1013的远端端部,该状态下的医用切割组件10适用于切割严重的、同轴的钙化病变部位;当伸出长度最小时,刀头101的远端的用于切割的部分最小,刀头101的切割能力相对最弱,此时分解件1021的近端端部抵持通槽1013的近端端部,该状态下的医用切割组件10适用于切割弯曲的、不规则的病变部位。因此,该实施例中医用切割组件10针对不同实际情况具有良好的适应性。
在实施例1中,分解件1021包括侧面1022,刀头101在旋转切割血管内多余组织时,被刀头101切碎的组织沿输送槽1012抵达通槽1013位置。此时限位件102相对固定,刀头101转动,输送槽1012跟随刀头101转动,既可带动输送槽1012中的组织转动,也带动通槽1013与分解件1021交合又分离,也即带动分解件1021的侧面1022不断进入和离开输送槽1012,此时组织与分解件1021的侧面1022不断发生碰撞并在错位后被切割,从而分解为更小体积的组织,更有利于后续的组织运输。在本实施例中,侧面1022设置为与分解件1021的近端端面或远端端面垂直的平面。
在另一实施例中,侧面1022设置为与分解件1021的近端端面或远端端面倾斜的倾斜面。
在另一实施例中,侧面1022也可以设置为非平面,例如,侧面1022可以设置为弧面或其他均匀曲面,也可以将侧面1022的一部分凸起或凹陷形成不规则表面。
如图5-6所示,图5是实施例1中减容导管系统远端的工作示意图,图6是实施例1中减容导管系统的工作示意图。减容导管系统11包括上述医用切割组件10和用于控制医用切割组件10的动作的控制组件12,刀头101由传动轴1015带动转动,第一套管103与限位件102刚性连接。在本实施例中,第一套管103和限位件102采用焊接,传动轴1015的远端穿过限位件102并连接刀头101,传动轴1015的近端连接体外的控制组件12,控制组件12通过控制传动轴1015的动作来控制刀头101的运动,以实现对组织的切割以及运输。刀头101的远端部分裸露,以实现对组织的切割,第一套管103至少覆盖刀头101的通槽1013,以实现对刀头101的径向限位,和充分防止刀头101运输的已切割组织沿径向离开输送槽1012。在刀头101的远端裸露部分切割组织后,待输送的组织沿着输送槽1012朝近端运动,在抵达通槽1013位置时被分解件1021碰撞分解成更小的组织,之后被继续朝近端运输,由于切割后的组织再次被分解为更小的组织,有利于快速和有效输送,从而整体上提升了切割和输送效率。
在需要调整刀头101的伸出长度时,保持限位件102当前位置不变,通过调整与刀头101近端连接的传动轴1015的轴向位置以实现对刀头101的轴向位置的调整。
进一步地,传动轴1015的表面设有螺旋延伸的运送槽1016,运送槽1016能将被分解件1021碰撞分解后的微小组织向传动轴1015的近端运输,直至最终运送到体外。此外,传动轴1015的表面套设有第二套管1017,起到与第一套管103相同的保护作用,应当理解,第一套管103和第二套管1017可以为一体结构,即作为一个完整套管发挥作用。第二套管1017一方面对传动轴1015所在位置的血管或外部组织起保护作用,另一方面防止待运送的微小组织沿径向脱离减容导管系统11。第二套管1017热熔连接于限位件102的近端,且与限位件102的近端过盈配合。
控制组件12包括开关组1210、动力组1220、传动组1230和分离座1240,其中,动力组1220和传动组1230刚性连接,传动组1230包括若干传动组合,本实施例选用齿轮组作为传动件,齿轮组的第一端连接动力组1220,第二端连接传动轴1015,且齿轮组与传动轴1015动密封连接。总的来说,开关组1210通过传动组1230控制传动轴1015的转动。具体地,传动轴1015安装在分离座1240内。
分离座1240包括第一腔室1241和第二腔室1242,第二腔室1242连通排液管道1243,第二套管1017套设在传动轴1015表面,为便于区别,减容导管系统的刀头101的切割位置为切割段,第二套管1017以及被保护套件1015套设的部分为运送段,控制组件12的部分为收集段。运送段从切割段刀头101的位置延伸至收集段的第一腔室1241内。在运送段的近端,第二套管1017的近端与第一腔室1241的内壁密封,传动轴1015继续延伸至第二腔室1242,传动轴1015的表面的运送槽1016也延伸至第二腔室1242,且传动轴1015的近端与第二腔室的内壁密封。因此,从切割段的刀头101的位置切下的组织会沿着运送槽1016逐渐进入收集段,具体的,组织逐渐进入第一腔室1241内部,然后抵达第二腔室1242的内部,最后随着排液管道1243排出至收集装置或者外界。
为了便于传动轴1015的加工和成型后的结构稳定,本实施例选用绕簧1018缠绕在传动轴1015的表面以形成运送槽1016。一方面,传动轴1015需要顺应血管而具有柔性,绕簧1018可以加强传动轴1015的支撑作用,即在保证传动轴1015能够顺应血管弯曲的前提下加强传动轴的支撑作用;另一方面,由于绕簧1018具有弹性,在刀头101转动切割时,可以起到缓冲作用。
本实施例中,运送段中还设有若干清解部,具体结合图7-8所示,图7是实施例1中减容导管系统的运送段的部分示意图,图8是图7中A-A位置的横截面示意图,第一清解部1023设置在运送段中,且第一清解部1023包括若干沿第二套管1017的内壁向轴线方向伸出的清解件10231(此处清解件10231可以与本实施例中的分解件结构相同),清解件10231的形状不做限定。当运送槽1016运送组织到第一清解部1023位置时,由于传动轴1015与第二套管1017相对转动,导致组织与第一清解部1023发生碰撞,从而分解成更小的部分。在运送段的上沿轴向设置多个第一清解部1023,可以进一步充分分解位于运送槽1016的组织,进而便于被切割的组织的运出。对一个特定的第一清解部1023而言,其包含的沿周向分布的清解件10231越多,第一清解部1023的分解效率越高。
在本实施例中,由于运送槽1016是由绕簧1018缠绕形成,为了保证第一清解部1023能充分接触运送槽1016运送的组织,将绕簧1018设为分段式结构,即绕簧1018在第一清解部1023位置断开,从而保证绕簧1018不会接触传动轴1015。
为了增强第一清解部1023的分解能力,在第一清解部1023的近端位置,在第二套管1017上设置带滤网的第一过滤件1019,被刀头切下来的组织向近端运输时,容易贴着第一清解部1023的凸起运动,而不与第一清解部1023发生碰撞,继而造成分解不充分的问题,因此,在清解件1024的附近补充设置第一过滤件1019,即清洁部1023包括清解件10231和位于清解件10231近端的第一过滤件1019,第一过滤件1019固定在传动轴1015上并与传动轴1015共同运动。如果第一过滤件1019设置在第一清解部1023的远端,则组织无法抵达第一清解部1023位置,因此,第一过滤件1019设置在第一清解部1023的近端一侧,优选的,第一过滤件1019的远端端面和第一清解部1023的近端端面接触,或第一过滤件1019的远端端面到第一清解部1023的近端端面的距离为0.1到5mm。具体工作情况如下:
传动轴1015相对于第二套管1017高速转动,清解件10231位于第二套管1017的内壁,第一过滤件1019固定在传动轴1015上且位于清解件10231的近端一侧,第一过滤件1019的外侧与第二套管1017件存在间隙,以避免过多的组织在第一过滤件1019表面堆积。第一过滤件1019随着传动轴1015相对于清解件10231转动,到达第一清解部1023位置的组织的一部分被清解件1024进一步清解,组织的另一部分贴着清解件10231的侧面和底面继续向运送段运输,故而没有被清解。此时在第一过滤件1019的作用下,原来没有被清解的部分组织被第一过滤件1019捕获,而清解件1024从第一过滤件1019表面经过,清解件10231的侧面和底面碰撞并分解被第一过滤件1019捕获的组织,从而实现进一步分解,从而使得第一清解部1023的清解效果更好。
而第一过滤件1019的滤网部分面积过大时,会影响液体的顺利流动,也造成第一过滤件1019转动的不稳定,因此,第一过滤件1019和第二套管1015间存在间隙1010,由于部分组织会通过第一过滤件1019和第二套管1015间的间隙1010直接传递而不被清解,因此,参照图9,可以在第一清解部1023的近端增加第二清解部1025。图9是本发明实施例1中的第二清解部1025的工作示意图,第二清解部1025包括清解件10241和第二过滤件1020,第二过滤件1020的结构不同于第一过滤件1019,第二过滤件1020通过若干连杆1021固定在传动轴1015上,值得注意的是,第二过滤件1020的滤网部分贴紧第二套管1017的内壁,也就是说,从第一过滤件1019的间隙1010处逃逸的组织会被第二过滤件1020捕获,从而被清解件10241清解。而第二过滤件1020的表面滤网的内侧与传动轴1015间留有空隙,既能避免组织在滤网表面堆积,又防止滤网过大影响液体流通。
进一步地,第二过滤件1020的径向厚度小于或等于清解件10241的径向厚度,清解件10241可以覆盖第二过滤件1020的全部表面,从而实现对组织的充分分解。
值得说明的是,实际上,第一清解部1023和第二清解部1024的相对位置可以不做限定,即可以设置多个第一清解部1023和第二清解部1024,但是优选的,至少对位于近端最远处的过滤件而言,该过滤件的远端设有至少一个清解件。
在另一实施例中,绕簧1018仍采用连续结构,第一清解部1023的凸起与绕簧1018间留有间隙。
在另一实施例中,如图10所示,图10是本发明实施例1中另一种减容导管系统的运送段的部分示意图,运送段的运送槽2016是传动轴2015的一部分,运送槽2016的侧壁2027沿着传动轴2015螺旋延伸,在清解件2023的位置,传动轴1015的侧壁2027的对应位置设有避让槽2028以避让清解件2023,避让槽2028贯穿侧壁2027并沿周向分布,当运送槽2016的避让槽2028与清解件2023在径向上重叠时,避让槽2028收容清解件2023,从而避免清解件2023与运送槽2016的侧壁2027发生碰撞。
在另一实施例中,减容导管系统的刀头101由传动轴1015驱动,而第二套管1017覆盖刀头101的近端一部分(即第二套管1017代替限位件延伸至刀头101位置),减容导管系统的第二套管1017沿轴向设有多个清解部,至少一个清解部位于刀头101的近端。
实施例2
如图11所示,图11是实施例2的减容导管系统中医用切割组件上限位件的结构示意图。实施例2的减容导管系统和医用切割组件与实施例1的减容导管系统和医用切割组件相同的部分在此不再赘述。在前面的实施例中,限位件与第一套管刚性连接,即限位件与第一套管作为一个整体发挥作用,限位件和第一套管既可以通过焊接、一体成型等方式形成一个整体,也可以改变限位件的结构,用限位件的一部分替代第一套管的作用。实施例2中的限位件,将分解件2021设置为位于限位件202的中部的内壁上。限位件202与刀头装配在一起后,限位件202的远端管壁的一部分至少套设在刀头的近端的外部。此时限位件202的远端管壁 的一部分发挥与前面实施例1中第一套管相同的作用。实施例2中的限位件202相对于实施例1中的限位件发生了结构上的改变,从而省去了第一套管的设计,提高了生产效率并减少了工艺成本,也不用考虑套管与限位件间可能存在的连接强度是否足够、密封性是否良好等加工问题。
后续涉及基于实施例2的改进方案中,第一套管一词指代本实施例中与第一套管起相同作用的限位件202的远端管壁的一部分。
实施例3
实施例3中,刀头与限位件的连接方式与实施例1中不同,套管的设置与实施例1中相同,实施例3的减容导管系统和医用切割组件与实施例1的减容导管系统和医用切割组件相同的部分在此不再赘述。
如图12-14所示,图12是实施例3中医用切割组件的爆炸示意图,图13是实施例3中医用切割组件中刀头和限位件的安装示意图,图14是实施例3中医用切割组件的限位件的结构示意图。在此实施例中,医用切割组件30包括同轴装配的刀头301、限位件302以及第一套管303。应当明确的是,除了刀头301与限位件302的连接位置结构改变,实施例3中其余与连接位置结构无关的结构、功能以及相关的扩展方案继续沿用实施例1中的内容。
实施例3中相邻两个刀刃3011间形成输送槽3012,刀头301的近端也设有多个通槽3013,每个通槽3013沿周向贯通其所在的刀刃3011并连通与该刀刃3011相邻的输送槽3012,应当说明的是,通槽3013位于刀刃3011的近端内侧,通槽3013的底面30131与刀刃3011近端的内壁表面30111形成台阶面,通槽3013的底面30131距离刀头301的回转轴轴线的距离大于刀刃3011近端的内壁表面30111到刀头301的回转轴轴线的距离。
限位件302包括分解件3021和连接部3022,分解件3021设置在连接部3022的远端靠近端部的位置处,分解件3021从连接部3022的外壁向外凸出。
在本实施例中,为了保证分解件3021能被容纳在通槽3013内,除了要满足实施例1中关于轴向宽度的相关设置外,还需要满足以下两个要求:
第一,分解件3021的顶面30211到限位件302的回转轴轴线的距离小于或等于通槽3013的底面30131距离刀头301的回转轴轴线的距离;
第二,刀刃3011近端的内壁表面30111到刀头301的回转轴轴线的距离大于或等于连接部3022的表面30221距离限位件302的回转轴轴线的距离。由于刀头301与限位件302同轴设置,刀头301的回转轴轴线和限位件302的回转轴轴线为同一直线。
刀头301在转动时,分解件3021交替地进入通槽3013和输送槽1012,分解件3021碰撞输送槽3012内的组织并将其分解为更小体积的组织。为了达到更好的分解效果,在满足上述要求的情况下,分解件3021的顶面30211到限位件302的回转轴轴线的距离大于或等于刀刃3011近端的内壁表面30111到刀头301的回转轴轴线的距离。
为了保证在实施例3的的减容导管系统中传动轴能正确带动刀头301转动,限位件302的中心部位设有贯穿其近端至远端的通道3023以便于传动轴伸入。
在另一实施例中,组织的输送通过刀头内部的输送腔进行,输送腔为设置在刀头内部的空腔,输送腔包括位于刀头远端的输入口以及位于刀头近端的输出口,输出口靠近通槽,被刀头远端切下的组织从输入口进入输送腔,从输出口离开输送腔,抵达通槽位置时与分解件结构碰撞而被进一步分解。
进一步地,可以在输送腔内部设置如实施例1中的输送槽结构,以便于组织的运输。
实施例4
基于实施例1-3,为了增加医用切割组件的分解效率,可以在套管(包括第一套管和第二套管)的内壁上设置分解槽,在刀头与套管发生相对转动时,输送槽内输送的多余组织与分解槽的侧壁发生碰撞实现了进一步分解,而分解槽的侧壁面积越大,分解效率越高,针对某一个形状固定的分解槽而言,在分解槽贯通套管的管壁形成窗口时,其对整个医用切割组件的分解效率提升最高。
如图15所示,图15是实施例5中减容导管系统远端的结构示意图,实施例4的减容导管系统和医用切割组件与实施例1-4中的减容导管系统和医用切割组件相同的部分在此不再赘述,实施例4的主要改进点在于,实施例4在医用切割组件的第一套管403上增设了一个分解槽,分解槽需要与输送槽(或输送腔)在至少某个时刻是连通的,这样可以使输送槽(或输送腔)内的组织进入分解槽内从而与分解槽的内侧壁发生碰撞实现进一步的分解,为了实现更好的效果,实施例4中的分解槽贯通了第一套管403的管壁形成第一窗口4031。第一窗口4031能一定程度上提升窗口位置的分解效率。具体地,在刀头401高速旋转时,输送槽(或输送腔)内的一部分切割下来的组织会与第一窗口4031的侧壁发生碰撞,从而进一步被分解。
由于第一窗口4031相对于第一套管403的整个表面很小,且第一套管403的外表面与血管内壁间隙较小,在刀头401高速旋转时,几乎没有待向近端运输的组织会从第一窗口4031离开医用切割组件。
为了得到更好的分解效果,第一窗口4031的设置满足:至少一个分解件沿轴向方向位于第一窗口4031的远端端部和近端端部之间。原因在于,医用切割组件中刀头与限位件发生相对旋转,带动输送槽与分解件发生相对旋转,分解件沿圆周方向与输送槽内的多余组织发生碰撞,导致输送槽内的多余组织被撞移位和发送进一步分解,被撞移位的多余组织一部分再次碰撞第一窗口4031的内壁,从而导致了更加进一步的分解,也就是说,分解件通过输送槽时带动输送槽内的多余组织与第一窗口4031的侧壁发生碰撞,使得第一窗口4031在该位置的分解效果最好。
实施例6
如图16所示,图16是实施例6中减容导管系统远端的结构示意图。实施例6的减容导管系统和医用切割组件基于实施例5改进,实施例6的减容导管系统和医用切割组件与实施例5的减容导管系统和医用切割组件相同的部分在此不再赘述,两者的主要区别在于,实施例3中医用切割组件在实施例5的基础上,再新增了一个分解槽,同样的,分解槽贯穿了第 一套管503的管壁,形成了第二窗口5032,原有的第一窗口位于第二窗口5032的背面故而未示出,第二窗口5032位于第一套管503的远端,第二窗口5032的侧壁与位于第一套管503远端内部的被切割下来的组织发生碰撞,这些组织被进一步分解成更小的组织,提高了医用切割组件在第一套管503的远端位置的分解效率。
实施例6是基于实施例5的单个分解槽的设计进行的改进,即实施例6是在与实施例5中的分解槽在限位件上不同的位置处新增分解槽以提高不同位置的分解效率,从而提高了医用切割组件的整体分解效率。因此,基于该思路,在限位件上设置多个分解槽的实施例应视为与实施例5或6等同的实施例。此外,在实施例5和实施例6这类在医用切割组件上新增分解槽的实施例中,对分解槽的具体形状均和数量均不作限定,为了得到更好的分解效果,至少一个分解件沿限位件的轴向方向位于其中一个分解槽的近端端部和远端端部之间。
应当说明的是,分解槽也可以运用于运送段中,与实施例5-6有所区别的是,为了保证运送段对切割组织的可靠运输,分解槽不能贯穿运送段的第二套管的外壁。
以上所述实施例仅表达了本发明的几种实施方式,其描述较为具体和详细,但并不能因此而理解为对发明专利范围的限制。应当指出的是,对于本领域的普通技术人员来说,在不脱离本发明构思的前提下,还可以做出若干变形和改进,这些都属于本发明的保护范围。因此,本发明专利的保护范围应以所附权利要求为准。
以上对本发明的实施例进行了具体说明,但本发明并不限于所述实施例,熟悉本领域的技术人员在不违背本发明精神的前提下还可做出种种的等同变形或替换,这些等同的变形或替换均包含在本申请权利要求所限定的范围内。此外,在不冲突的情况下,本发明的实施例及实施例中的特征可以相互组合。
Claims (18)
- 一种医用切割组件,包括刀头和与所述刀头转动连接的限位件,其特征在于,所述刀头包括输送部,所述限位件包括分解部,所述刀头与所述限位件相对转动时,所述分解部穿过所述输送部。
- 根据权利要求1所述的医用切割组件,其特征在于,所述刀头包括切割部,所述切割部包括从近端到远端延伸的多个刀刃,所述输送部包括位于相邻两个所述刀刃之间的输送槽,至少一个所述刀刃上设有通槽,所述通槽和与所述刀刃相邻的所述输送槽连通,所述刀头与所述限位件相对转动时,所述分解部多次穿过所述输送槽。
- 根据权利要求2所述的医用切割组件,其特征在于,所述分解部有一个或多个,所述刀头在转动的过程中,始终有至少一个所述分解部的至少一部分位于一个所述通槽内,以对所述刀头进行轴向限位。
- 根据权利要求2所述的医用切割组件,其特征在于,所述分解部有多个,至少两个所述分解部沿所述限位件的周向方向或轴向方向间隔设置。
- 根据权利要求2所述的医用切割组件,其特征在于,所述刀刃从近端到远端呈螺旋状延伸,所述输送槽的螺旋角从远端至近端逐渐减小。
- 根据权利要求2所述的医用切割组件,其特征在于,所述医用切割组件还包括与所述限位件连接的套管,所述套管套设在所述刀头和所述限位件的外部,且所述套管在轴向上至少覆盖所述分解部。
- 根据权利要求6所述的医用切割组件,其特征在于,所述套管上设有若干分解槽,所述刀头与所述限位件相对转动时,所述分解槽与所述输送部至少在某一时刻连通。
- 根据权利要求2所述的医用切割组件,其特征在于,所述分解部位于所述限位件的中部,且所述限位件的一部分至少套设在所述刀头的近端的外部。
- 根据权利要求6或8所述的医用切割组件,其特征在于,所述分解部的轴向宽度小于所述通槽的轴向宽度,所述分解部的近端端部相对于所述通槽的近端端部的轴向位置可调。
- 一种减容导管系统,包括连续设置的切割段和运送段,所述切割段包括切割组件,所述运送段包括与切割组件固定连接的传动轴和套设在所述传动轴表面的套管,所述传动轴能与所述套管发生相对转动,其特征在于,所述传动轴上设有运送槽,所述套管沿轴向设有清解件,所述传动轴沿轴向设有过滤件。
- 根据权利要求10所述的减容导管系统,其特征在于,所述清解件为多个,所述过滤件为多个,至少一个所述清解件位于全部所述过滤件的远端。
- 根据权利要求10所述的减容导管系统,其特征在于,还包括至少一个清解部,所述清解部包括所述清解件与位于其近端的过滤件,所述过滤件包括第一过滤件和/或第二过滤件。
- 根据权利要求12所述的减容导管系统,其特征在于,所述过滤件包括第一过滤件, 所述第一过滤件的外侧与所述套管的内壁间留有间隙。
- 根据权利要求12所述的减容导管系统,其特征在于,所述过滤件包括第二过滤件,所述第二过滤件的内侧与所述传动轴间留有间隙。
- 根据权利要求14所述的减容导管系统,其特征在于,所述第二过滤件通过连杆固定在所述传动轴上,所述第二过滤件的外侧贴紧所述套管的内壁。
- 根据权利要求15所述的减容导管系统,其特征在于,所述过滤件的径向厚度小于或等于所述分解件的径向厚度。
- 根据权利要求12所述的减容导管系统,其特征在于,所述清解部包括具有所述第一过滤件的第一清解部和具有所述第二过滤件的第二清解部,所述第一清解部和所述第二清解部依次交替排列。
- 一种减容导管系统,包括连续设置的切割段和运送段,所述切割段包括切割组件,所述运送段包括与切割组件固定连接的传动轴和套设在所述传动轴表面的套管,所述传动轴能与所述套管发生相对转动,其特征在于,所述传动轴上设有运送槽,所述套管内壁设有清解部,所述清解部包括朝向所述传动轴延伸的分解件。
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116919535A (zh) * | 2022-10-13 | 2023-10-24 | 以诺康医疗科技(苏州)有限公司 | 一种超声手术刀头 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070265647A1 (en) * | 2006-05-09 | 2007-11-15 | Possis Medical, Inc. | Atherectomy system having a variably exposed cutter |
CN101795630A (zh) * | 2007-06-29 | 2010-08-04 | 阿瑟罗迈德公司 | 旋切术装置、系统和方法 |
US20100324472A1 (en) * | 2007-11-14 | 2010-12-23 | Pathway Medical Technologies, Inc. | Delivery and administration of compositions using interventional catheters |
CN101511284B (zh) * | 2006-06-30 | 2011-11-09 | 阿瑟罗迈德公司 | 动脉粥样硬化切除术装置和方法 |
WO2014059150A1 (en) * | 2012-10-10 | 2014-04-17 | Avinger, Inc. | Occlusion-crossing devices |
US20150133977A1 (en) * | 2006-06-30 | 2015-05-14 | Atheromed, Inc. | Devices, systems, and methods for cutting and removing occlusive material from a body lumen |
US20170360467A1 (en) * | 2006-12-22 | 2017-12-21 | The Spectranetics Corporation | Retractable separating systems and methods |
CN109717925A (zh) * | 2018-10-22 | 2019-05-07 | 杭州巴泰医疗器械有限公司 | 一种可变切削直径的腔内斑块清理单元 |
-
2021
- 2021-09-02 EP EP21863650.4A patent/EP4209184A1/en active Pending
- 2021-09-02 WO PCT/CN2021/116163 patent/WO2022048586A1/zh active Application Filing
- 2021-09-02 US US18/024,228 patent/US20230263549A1/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070265647A1 (en) * | 2006-05-09 | 2007-11-15 | Possis Medical, Inc. | Atherectomy system having a variably exposed cutter |
CN101511284B (zh) * | 2006-06-30 | 2011-11-09 | 阿瑟罗迈德公司 | 动脉粥样硬化切除术装置和方法 |
US20150133977A1 (en) * | 2006-06-30 | 2015-05-14 | Atheromed, Inc. | Devices, systems, and methods for cutting and removing occlusive material from a body lumen |
US20170360467A1 (en) * | 2006-12-22 | 2017-12-21 | The Spectranetics Corporation | Retractable separating systems and methods |
CN101795630A (zh) * | 2007-06-29 | 2010-08-04 | 阿瑟罗迈德公司 | 旋切术装置、系统和方法 |
US20100324472A1 (en) * | 2007-11-14 | 2010-12-23 | Pathway Medical Technologies, Inc. | Delivery and administration of compositions using interventional catheters |
WO2014059150A1 (en) * | 2012-10-10 | 2014-04-17 | Avinger, Inc. | Occlusion-crossing devices |
CN109717925A (zh) * | 2018-10-22 | 2019-05-07 | 杭州巴泰医疗器械有限公司 | 一种可变切削直径的腔内斑块清理单元 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116919535A (zh) * | 2022-10-13 | 2023-10-24 | 以诺康医疗科技(苏州)有限公司 | 一种超声手术刀头 |
CN116919535B (zh) * | 2022-10-13 | 2024-05-07 | 以诺康医疗科技(苏州)有限公司 | 一种超声手术刀头 |
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