WO2021197994A1 - Pompe comportant des polymères électroactifs - Google Patents

Pompe comportant des polymères électroactifs Download PDF

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Publication number
WO2021197994A1
WO2021197994A1 PCT/EP2021/057684 EP2021057684W WO2021197994A1 WO 2021197994 A1 WO2021197994 A1 WO 2021197994A1 EP 2021057684 W EP2021057684 W EP 2021057684W WO 2021197994 A1 WO2021197994 A1 WO 2021197994A1
Authority
WO
WIPO (PCT)
Prior art keywords
pump
electroactive polymer
pumps
blood treatment
pump according
Prior art date
Application number
PCT/EP2021/057684
Other languages
German (de)
English (en)
Inventor
Stephanie Appel
Tobias Stöckerl
David HANNES
Gerome FISCHER
Original Assignee
Fresenius Medical Care Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Medical Care Deutschland Gmbh filed Critical Fresenius Medical Care Deutschland Gmbh
Priority to EP21716971.3A priority Critical patent/EP4128376A1/fr
Publication of WO2021197994A1 publication Critical patent/WO2021197994A1/fr

Links

Classifications

    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02N—ELECTRIC MACHINES NOT OTHERWISE PROVIDED FOR
    • H02N2/00—Electric machines in general using piezoelectric effect, electrostriction or magnetostriction
    • H02N2/02—Electric machines in general using piezoelectric effect, electrostriction or magnetostriction producing linear motion, e.g. actuators; Linear positioners ; Linear motors
    • H02N2/04—Constructional details
    • H02N2/043—Mechanical transmission means, e.g. for stroke amplification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
    • F04B19/20—Other positive-displacement pumps
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N—ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N30/00—Piezoelectric or electrostrictive devices
    • H10N30/50—Piezoelectric or electrostrictive devices having a stacked or multilayer structure
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N—ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10N30/00—Piezoelectric or electrostrictive devices
    • H10N30/80—Constructional details
    • H10N30/85—Piezoelectric or electrostrictive active materials
    • H10N30/857—Macromolecular compositions
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F05—INDEXING SCHEMES RELATING TO ENGINES OR PUMPS IN VARIOUS SUBCLASSES OF CLASSES F01-F04
    • F05C—INDEXING SCHEME RELATING TO MATERIALS, MATERIAL PROPERTIES OR MATERIAL CHARACTERISTICS FOR MACHINES, ENGINES OR PUMPS OTHER THAN NON-POSITIVE-DISPLACEMENT MACHINES OR ENGINES
    • F05C2231/00—Organic materials not otherwise provided for
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F05—INDEXING SCHEMES RELATING TO ENGINES OR PUMPS IN VARIOUS SUBCLASSES OF CLASSES F01-F04
    • F05C—INDEXING SCHEME RELATING TO MATERIALS, MATERIAL PROPERTIES OR MATERIAL CHARACTERISTICS FOR MACHINES, ENGINES OR PUMPS OTHER THAN NON-POSITIVE-DISPLACEMENT MACHINES OR ENGINES
    • F05C2251/00—Material properties
    • F05C2251/08—Shape memory

Definitions

  • Another aspect of the invention relates to a use, for example a shoring, of a pump according to the invention in a blood treatment device, for example a dialysis machine.
  • one or more solutions are fed / metered into the line system for conveying fresh dialysis fluid at a point at which the dialysis fluid has left the balance device.
  • fresh dialysis fluid is preferably withdrawn from the line at a point at which the dialysis fluid has not yet reached the balancing device.
  • Another aspect of the invention relates to a method for measuring a printer attitude in a filter, in particular in a filter for filtering dialysing fluid or in a dialyzer, a pump according to the invention being used in the context of the method.
  • the self-sensing property of the electroactive polymer is used.
  • a defined volume of fluid is introduced into the filter to be tested.
  • the defined volume of fluid in the filter generates a certain internal pressure in the filter, which acts on the electroactive polymer in the pump.
  • the elastic polymer changes its expansion, which can be recorded by means of a measuring unit (capacitance, impedance). Any pressure loss in the filter, for example due to a leak, is thus reflected in the measured impedance profile of the electroactive polymer and can thus be recorded. If the impedance and thus the pressure in the filter remain constant, it can be concluded that the filter is intact.
  • Fig. 1 is a schematic drawing of a pump according to the invention.
  • FIG. 2 shows a flow diagram which illustrates the use of pumps according to the invention in the context of an embodiment of a blood treatment machine.
  • Fig. 3 shows the embodiment of Fig. 2 with multi-way valves instead of standard valves.
  • Fig. 4 is a flow chart which illustrates the use of pumps according to the invention in the context of another embodiment of a blood treatment machine.
  • Fig. 5 shows the embodiment from Fig. 4 with multi-way valves instead of standard valves.
  • Fig. 6 is a flow chart which ver illustrates the use of pumps according to the invention in the context of yet another embodiment of a blood treatment machine.
  • the force bundling structure 4 is connected to a pump membrane 5, which is moved up and down in accordance with the deformation of the stack 2 of electroactive polymers.
  • the longitudinal direction of the stacks 2 of electroactive polymers and the direction of the deformation of the stacks 2 are thus aligned parallel to the direction of the pump strokes of the pump 1.
  • FIG. 2 a flow diagram is reproduced which illustrates the use of pumps according to the invention in the context of a blood treatment machine.
  • the patient's blood is brought into contact with dialysis fluid in a dialyzer through semi-permeable hollow fiber membranes.
  • This membrane allows substances, especially toxins, electrolytes and proteins, to diffuse back and forth between the liquids. Since diffusion is a process driven by concentration, the aim is to prevent foreign substances from entering the patient's blood diffuse, the dialysis fluid, the so-called dialysate, consists of ultrapure water.
  • An additional dialyzing fluid filter F04 with a dead volume of, for example, approx. 300 ml is arranged between the balancing chamber and the dialyzer. This dead volume is relevant for the consideration of river peaks and their smoothing, furthermore this dead volume functions like a kind of fluid reservoir.
  • the physiological solution reaches the dialyser from the dialysis fluid filter F04, where it is used to clean the blood. After the blood has been cleaned, the dialysis fluid is fed back into the balancing chamber H14 via a pump and finally ends up in the drain.
  • EAP pump 7 in the stored course to / downstream of the patient “To Pat”. Since the volume metered in by means of the EAP pump 6 is known, the same volume can be removed again in a simple manner.
  • the EAP pumps mentioned here can be viewed as volumetric dosing systems. This means that dosing takes place by emptying a known pump chamber, i.e. a volume. Since the metered media are preferably liquid The amount delivered - the dose - is clearly defined with the volume or corresponds to the volume delivered by a pump stroke or a certain number of pump strokes therefore, as an intrinsic property, a higher repeatability, i.e. a higher accuracy for repeated processes.
  • a further balancing device 9 with a possibly smaller balancing chamber can be placed between the two pumps 5 and 6 and the line 8 into which the dosing is carried out 9a, as shown schematically in Fig. 3a.
  • the dialyzer is marked with D
  • the patient with P and the balancing device H 14 comprises two balancing chambers 14 a and 14 b.
  • the balancing device 9 or the balancing chamber 9a can be used to redundantly check that the dosing by the EAP pumps was exact and that increased safety is achieved as a result: This also ensures that the dosing volume is withdrawn again exactly which was previously added to the dialysate circuit during dosing.
  • any other pumps can be used for dosing instead of EAP pumps, such as peristaltic pumps, Diaphragm pumps, gear pumps, centrifugal pumps - for example impeller pumps.
  • the properties (small strokes, high frequencies) of the pumps according to the invention make it possible to combine different pump functions (e.g. pumping different solutions).
  • a blood treatment machine in which a bi-carbonate, a concentrate and an ultrafiltration pump (UF pump) are designed as pumps according to the invention.
  • the UF pump must be able to do this be able to withdraw both the usual volume to be withdrawn per treatment and the electrolyte and bicarbonate volume to be dosed.
  • a single pump according to the invention can also pump bicarbonate and concentrate and a UF pump can also be provided, which is either a pump according to the invention with electroactive polymers or a conventional series pump.
  • a pump according to the invention in addition a UF pump and a balance pump can be provided, each of which is either a pump according to the invention with electroactive polymers or a conventional series pump.
  • the task of the balance pump is to remove the volume supplied via the bicarbonate / concentrate pump.
  • the UF pump therefore only has to deliver the usual UF volume.
  • the functions of the bicarbonate, concentrate and UF pumps could also be combined in a single pump according to the invention, which is preferably present at least twice in the blood treatment device.
  • the first EAP pump 6 takes over the dosing / feeding of bicarbonate and concentrate; whereby, as shown in FIG. 5, a multi-way valve can be used to switch between the two fluids.
  • the fluids can also be switched using regular valves (see FIG. 4). Since the dosing / feeding takes place downstream of the balancing chamber but upstream of the patient (see flow path “Before Pat”), the amount of fluid fed in must be removed again in order to prevent overhydration of the patient. Therefore, after the patient (see flow path “After Pat”), fluid is withdrawn from the system, which is taken over by the second EAP pump 7. The original UF pump P04 remains in the system.
  • a pump always has certain tolerances and thus a certain inaccuracy when pumping a defined volume. This leads to errors occurring both when adding (dosing errors) and when removing liquid. Viewed as a whole, this leads to accounting errors.
  • the EAP pump used or several EAP pumps used with the associated valves can be installed in a pump unit.
  • the metering pump (s) and the valves are preferably installed on one unit and can be operated by a central control. This can also include valves, which are required to feed fluids downstream of the balancing chamber.
  • This own control unit has its own CPU, for example, which enables significantly shorter processing times compared to using the machine software. This reduced processing time makes it possible to achieve higher pump frequencies.
  • the only input parameter required is the desired delivery rate; the required frequency and the required pump volume are then preferably calculated by the separate control unit.
  • FIG. 6 shows a further embodiment of a blood treatment machine which has a pump 6 according to the invention and an ultrafiltration pump P04.
  • the pump 6 according to the invention pumps both concentrate and bicarbonate and the ultrafiltration pump P04 is preferably also designed as an EAP pump according to the invention, but can also be a different type of pump.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Mechanical Engineering (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • External Artificial Organs (AREA)

Abstract

La présente invention concerne une pompe (1) comprenant un actionneur de pompe (2) qui comprend au moins un polymère électroactif, l'au moins un polymère électroactif étant disposé de telle sorte qu'une déformation de l'au moins un polymère électroactif se produit le long de la direction de la course de pompage de la pompe. L'invention concerne également une machine de traitement de sang comprenant une telle pompe. Un autre aspect de l'invention concerne un procédé de mesure de maintenance de pression utilisant une telle pompe.
PCT/EP2021/057684 2020-03-30 2021-03-25 Pompe comportant des polymères électroactifs WO2021197994A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP21716971.3A EP4128376A1 (fr) 2020-03-30 2021-03-25 Pompe comportant des polymères électroactifs

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102020108755.1A DE102020108755A1 (de) 2020-03-30 2020-03-30 Pumpe mit elektroaktiven Polymeren
DE102020108755.1 2020-03-30

Publications (1)

Publication Number Publication Date
WO2021197994A1 true WO2021197994A1 (fr) 2021-10-07

Family

ID=75426560

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2021/057684 WO2021197994A1 (fr) 2020-03-30 2021-03-25 Pompe comportant des polymères électroactifs

Country Status (3)

Country Link
EP (1) EP4128376A1 (fr)
DE (1) DE102020108755A1 (fr)
WO (1) WO2021197994A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003081762A1 (fr) * 2002-03-18 2003-10-02 Sri International Dispositifs de polymere electro-actif pour deplacement de fluide
DE102014218981A1 (de) * 2013-11-20 2015-05-21 Robert Bosch Gmbh Druckerzeugungsvorrichtung mit EAP Aktor
DE102016010222A1 (de) * 2016-08-20 2018-02-22 Fresenius Medical Care Deutschland Gmbh Vorrichtung und Verfahren zur Bereitstellung von Dialysierflüssigkeit und Dialysevorrichtung
EP3490017A1 (fr) * 2017-11-27 2019-05-29 Siemens Aktiengesellschaft Dispositif d'actionnement pourvu d'actionneur de corps fixe et d'unité hydraulique

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003081762A1 (fr) * 2002-03-18 2003-10-02 Sri International Dispositifs de polymere electro-actif pour deplacement de fluide
DE102014218981A1 (de) * 2013-11-20 2015-05-21 Robert Bosch Gmbh Druckerzeugungsvorrichtung mit EAP Aktor
DE102016010222A1 (de) * 2016-08-20 2018-02-22 Fresenius Medical Care Deutschland Gmbh Vorrichtung und Verfahren zur Bereitstellung von Dialysierflüssigkeit und Dialysevorrichtung
EP3490017A1 (fr) * 2017-11-27 2019-05-29 Siemens Aktiengesellschaft Dispositif d'actionnement pourvu d'actionneur de corps fixe et d'unité hydraulique

Also Published As

Publication number Publication date
EP4128376A1 (fr) 2023-02-08
DE102020108755A1 (de) 2021-09-30

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