WO2021158509A1 - Transcatheter heart valve prosthesis assembled inside heart chambers or blood vessels - Google Patents
Transcatheter heart valve prosthesis assembled inside heart chambers or blood vessels Download PDFInfo
- Publication number
- WO2021158509A1 WO2021158509A1 PCT/US2021/016150 US2021016150W WO2021158509A1 WO 2021158509 A1 WO2021158509 A1 WO 2021158509A1 US 2021016150 W US2021016150 W US 2021016150W WO 2021158509 A1 WO2021158509 A1 WO 2021158509A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- valve
- catheter
- anterior
- transcatheter
- flap
- Prior art date
Links
- 210000003709 heart valve Anatomy 0.000 title claims abstract description 49
- 210000004204 blood vessel Anatomy 0.000 title claims description 14
- 210000005242 cardiac chamber Anatomy 0.000 title claims description 6
- 210000002216 heart Anatomy 0.000 claims abstract description 38
- 210000000591 tricuspid valve Anatomy 0.000 claims description 111
- 238000004873 anchoring Methods 0.000 claims description 84
- 210000005241 right ventricle Anatomy 0.000 claims description 40
- 238000000034 method Methods 0.000 claims description 28
- 210000005245 right atrium Anatomy 0.000 claims description 24
- 239000000463 material Substances 0.000 claims description 16
- 210000004115 mitral valve Anatomy 0.000 claims description 9
- 210000003102 pulmonary valve Anatomy 0.000 claims description 8
- 210000001765 aortic valve Anatomy 0.000 claims description 6
- 230000017531 blood circulation Effects 0.000 claims description 6
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 claims description 6
- 229910001000 nickel titanium Inorganic materials 0.000 claims description 6
- 230000002861 ventricular Effects 0.000 claims description 5
- 238000005452 bending Methods 0.000 claims description 4
- 229910000831 Steel Inorganic materials 0.000 claims description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 3
- 239000000560 biocompatible material Substances 0.000 claims description 3
- 229910017052 cobalt Inorganic materials 0.000 claims description 3
- 239000010941 cobalt Substances 0.000 claims description 3
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims description 3
- 229910001220 stainless steel Inorganic materials 0.000 claims description 3
- 239000010935 stainless steel Substances 0.000 claims description 3
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- 229910052719 titanium Inorganic materials 0.000 claims description 3
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- 210000001520 comb Anatomy 0.000 claims description 2
- 230000001746 atrial effect Effects 0.000 description 13
- 239000008280 blood Substances 0.000 description 11
- 210000004369 blood Anatomy 0.000 description 11
- 210000001519 tissue Anatomy 0.000 description 10
- 229920000295 expanded polytetrafluoroethylene Polymers 0.000 description 9
- 238000013461 design Methods 0.000 description 8
- 229920000728 polyester Polymers 0.000 description 7
- 238000007789 sealing Methods 0.000 description 7
- 229920004934 Dacron® Polymers 0.000 description 6
- 239000004699 Ultra-high molecular weight polyethylene Substances 0.000 description 6
- 210000005246 left atrium Anatomy 0.000 description 6
- 210000005240 left ventricle Anatomy 0.000 description 6
- 239000005020 polyethylene terephthalate Substances 0.000 description 6
- 229920000785 ultra high molecular weight polyethylene Polymers 0.000 description 6
- 201000001943 Tricuspid Valve Insufficiency Diseases 0.000 description 5
- 230000009466 transformation Effects 0.000 description 5
- 241000283690 Bos taurus Species 0.000 description 4
- 241000283073 Equus caballus Species 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 4
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- 210000003516 pericardium Anatomy 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 3
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- 150000001299 aldehydes Chemical class 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 3
- 229920000249 biocompatible polymer Polymers 0.000 description 3
- 239000003431 cross linking reagent Substances 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 3
- 229920001778 nylon Polymers 0.000 description 3
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- 229920002635 polyurethane Polymers 0.000 description 3
- 239000004814 polyurethane Substances 0.000 description 3
- 230000002685 pulmonary effect Effects 0.000 description 3
- 210000002620 vena cava superior Anatomy 0.000 description 3
- 206010044640 Tricuspid valve incompetence Diseases 0.000 description 2
- 210000000709 aorta Anatomy 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 210000004351 coronary vessel Anatomy 0.000 description 2
- 230000010339 dilation Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 230000037361 pathway Effects 0.000 description 2
- 210000001147 pulmonary artery Anatomy 0.000 description 2
- 238000012876 topography Methods 0.000 description 2
- 230000000472 traumatic effect Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 210000001631 vena cava inferior Anatomy 0.000 description 2
- 206010061818 Disease progression Diseases 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
- 208000031481 Pathologic Constriction Diseases 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 230000005750 disease progression Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000003191 femoral vein Anatomy 0.000 description 1
- 210000004013 groin Anatomy 0.000 description 1
- 210000002837 heart atrium Anatomy 0.000 description 1
- 230000008588 hemolysis Effects 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
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- 238000012856 packing Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 230000036262 stenosis Effects 0.000 description 1
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- 238000001356 surgical procedure Methods 0.000 description 1
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- 210000005166 vasculature Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2427—Devices for manipulating or deploying heart valves during implantation
- A61F2/2436—Deployment by retracting a sheath
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21750572.6A EP4099957A4 (de) | 2020-02-06 | 2021-02-02 | In herzkammern oder blutgefässen montierte transkatheter-herzklappenprothese |
| IL295253A IL295253A (en) | 2020-02-06 | 2021-02-02 | A transcatheter heart valve prosthesis is assembled inside heart chambers or blood vessels |
| AU2021217945A AU2021217945A1 (en) | 2020-02-06 | 2021-02-02 | Transcatheter heart valve prosthesis assembled inside heart chambers or blood vessels |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062970967P | 2020-02-06 | 2020-02-06 | |
| US62/970,967 | 2020-02-06 | ||
| US202063130201P | 2020-12-23 | 2020-12-23 | |
| US63/130,201 | 2020-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2021158509A1 true WO2021158509A1 (en) | 2021-08-12 |
Family
ID=77178636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2021/016150 WO2021158509A1 (en) | 2020-02-06 | 2021-02-02 | Transcatheter heart valve prosthesis assembled inside heart chambers or blood vessels |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US11109965B2 (de) |
| EP (1) | EP4099957A4 (de) |
| AU (1) | AU2021217945A1 (de) |
| IL (1) | IL295253A (de) |
| WO (1) | WO2021158509A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111655201A (zh) * | 2018-02-15 | 2020-09-11 | 医疗系统公司 | 具有改进的固定特征的支架和置换心脏瓣膜假体 |
| WO2019195860A2 (en) | 2018-04-04 | 2019-10-10 | Vdyne, Llc | Devices and methods for anchoring transcatheter heart valve |
| US11344413B2 (en) | 2018-09-20 | 2022-05-31 | Vdyne, Inc. | Transcatheter deliverable prosthetic heart valves and methods of delivery |
| CA3132162A1 (en) | 2019-03-05 | 2020-09-10 | Vdyne, Inc. | Tricuspid regurgitation control devices for orthogonal transcatheter heart valve prosthesis |
| EP3965701A4 (de) | 2019-05-04 | 2023-02-15 | Vdyne, Inc. | Cinchvorrichtung und verfahren zum einsatz einer seitlich freigesetzten herzklappenprothese in einem nativen ring |
| AU2020334080A1 (en) | 2019-08-20 | 2022-03-24 | Vdyne, Inc. | Delivery and retrieval devices and methods for side-deliverable transcatheter prosthetic valves |
| CN114630665A (zh) | 2019-08-26 | 2022-06-14 | 维迪内股份有限公司 | 可侧面输送的经导管假体瓣膜及其输送和锚定方法 |
| US11234813B2 (en) * | 2020-01-17 | 2022-02-01 | Vdyne, Inc. | Ventricular stability elements for side-deliverable prosthetic heart valves and methods of delivery |
| WO2021158509A1 (en) * | 2020-02-06 | 2021-08-12 | Laplace Interventional Inc. | Transcatheter heart valve prosthesis assembled inside heart chambers or blood vessels |
| US11510777B1 (en) | 2022-02-10 | 2022-11-29 | Laplace Interventional Inc. | Prosthetic heart valves |
| US11712336B1 (en) | 2022-07-20 | 2023-08-01 | Laplace Interventional Inc. | Prosthetic heart valves |
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| US9681951B2 (en) * | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
| US20180000586A1 (en) * | 2014-10-23 | 2018-01-04 | Caisson Interventional, LLC | Systems and methods for heart valve therapy |
| US20190008635A1 (en) | 2017-07-06 | 2019-01-10 | Twelve, Inc. | Prosthetic heart valve devices and associated systems and methods |
| US10321995B1 (en) | 2018-09-20 | 2019-06-18 | Vdyne, Llc | Orthogonally delivered transcatheter heart valve replacement |
| US20200268512A1 (en) * | 2017-03-06 | 2020-08-27 | Avvie Gmbh | Implant and method for improving coaptation of an atrioventricular valve |
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-
2021
- 2021-02-02 WO PCT/US2021/016150 patent/WO2021158509A1/en unknown
- 2021-02-02 IL IL295253A patent/IL295253A/en unknown
- 2021-02-02 EP EP21750572.6A patent/EP4099957A4/de active Pending
- 2021-02-02 US US17/165,244 patent/US11109965B2/en active Active
- 2021-02-02 AU AU2021217945A patent/AU2021217945A1/en active Pending
- 2021-09-02 US US17/465,172 patent/US11337801B2/en active Active
-
2022
- 2022-05-18 US US17/747,523 patent/US11701223B2/en active Active
-
2023
- 2023-05-25 US US18/201,900 patent/US20230320846A1/en active Pending
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| US9393110B2 (en) * | 2010-10-05 | 2016-07-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
| US20170128209A1 (en) | 2011-10-19 | 2017-05-11 | Twelve, Inc. | Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods |
| US9681951B2 (en) * | 2013-03-14 | 2017-06-20 | Edwards Lifesciences Cardiaq Llc | Prosthesis with outer skirt and anchors |
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Also Published As
| Publication number | Publication date |
|---|---|
| IL295253A (en) | 2022-10-01 |
| AU2021217945A1 (en) | 2022-08-25 |
| EP4099957A4 (de) | 2023-06-21 |
| US20210244535A1 (en) | 2021-08-12 |
| US20230320846A1 (en) | 2023-10-12 |
| EP4099957A1 (de) | 2022-12-14 |
| US20220273427A1 (en) | 2022-09-01 |
| US20210393401A1 (en) | 2021-12-23 |
| US11337801B2 (en) | 2022-05-24 |
| US11109965B2 (en) | 2021-09-07 |
| US11701223B2 (en) | 2023-07-18 |
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