WO2021145791A1 - Membrane de collagène ultrafine super-résistante et procédé de production - Google Patents

Membrane de collagène ultrafine super-résistante et procédé de production Download PDF

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Publication number
WO2021145791A1
WO2021145791A1 PCT/RU2020/050358 RU2020050358W WO2021145791A1 WO 2021145791 A1 WO2021145791 A1 WO 2021145791A1 RU 2020050358 W RU2020050358 W RU 2020050358W WO 2021145791 A1 WO2021145791 A1 WO 2021145791A1
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WO
WIPO (PCT)
Prior art keywords
solution
collagen
squid
biological tissue
collagen membrane
Prior art date
Application number
PCT/RU2020/050358
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English (en)
Russian (ru)
Inventor
Ефим Семенович ВАЙНЕРМАН
Original Assignee
Ефим Семенович ВАЙНЕРМАН
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ефим Семенович ВАЙНЕРМАН filed Critical Ефим Семенович ВАЙНЕРМАН
Publication of WO2021145791A1 publication Critical patent/WO2021145791A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C14—SKINS; HIDES; PELTS; LEATHER
    • C14C—CHEMICAL TREATMENT OF HIDES, SKINS OR LEATHER, e.g. TANNING, IMPREGNATING, FINISHING; APPARATUS THEREFOR; COMPOSITIONS FOR TANNING
    • C14C1/00—Chemical treatment prior to tanning
    • C14C1/08—Deliming; Bating; Pickling; Degreasing

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Polymers & Plastics (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Materials Engineering (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)

Abstract

Ce groupe d'invention se rapporte au domaine de l'ingénierie tissulaire et notamment à des membranes de collagène que l'on utilise comme xéno-implants, et concerne une membrane de collagène faite de tissus biologiques de calmar, ainsi qu'un procédé de production de celle-ci. Cette membrane de collagène en tissus biologiques de calmar du genre Dosidicus Gigas de la famille des Ommastrephinae possède une résistance à la traction de 150-250 MPa, un allongement relatif à la rupture d'au moins 20%, une épaisseur de 20 à 100 microns avec un écart de l'épaisseur par rapport à la valeur moyenne de moins de 5%, et avec un contenu en collagène d'au moins 98% en termes de substance absolument sèche. Le procédé de production consiste séparer la carcasse du calmar en parties anatomiques distinctes selon un procédé mécanique en séparant les tissus biologiques conjonctifs de couverture du manteau, lesquels sont ensuite trempés dans une solution de sel neutre, dans une solution faiblement alcaline contenant des ferments lipolytiques et protéolytiques, puis rincés avec de l'eau, avec une solution d'acide ayant une forte action ionique puis avec une solution alcaline et de l'eau distillée avant d'être séchés. La membrane de collagène possède une biocompatibilité et une capacité de résorption dans des conditions physiologiques, et peut être utilisée comme xéno-implant en ingénierie tissulaire, pour la croissance de cultures cellulaires et dans manipulations cosmétiques, pratiquement sans aucune limitation.
PCT/RU2020/050358 2020-01-16 2020-12-01 Membrane de collagène ultrafine super-résistante et procédé de production WO2021145791A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU2020101532A RU2737358C1 (ru) 2020-01-16 2020-01-16 Сверхпрочная ультратонкая коллагеновая мембрана и способ ее получения
RU2020101532 2020-01-16

Publications (1)

Publication Number Publication Date
WO2021145791A1 true WO2021145791A1 (fr) 2021-07-22

Family

ID=73543584

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2020/050358 WO2021145791A1 (fr) 2020-01-16 2020-12-01 Membrane de collagène ultrafine super-résistante et procédé de production

Country Status (2)

Country Link
RU (1) RU2737358C1 (fr)
WO (1) WO2021145791A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114225112A (zh) * 2021-11-22 2022-03-25 江苏苏伯纳生物科技有限公司 一种脑脊液隔离修复膜的制备方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102676620A (zh) * 2011-12-20 2012-09-19 浙江省海洋开发研究院 一种高分子量鱿鱼皮胶原蛋白的制备方法
US9315562B2 (en) * 2010-11-26 2016-04-19 Tokyo Institute Of Technology High-strength collagen fiber membrane and a manufacturing method thereof
RU2614273C2 (ru) * 2014-11-24 2017-03-24 Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет инженерных технологий" (ФГБОУ ВО "ВГУИТ"). Способ получения коллагенового продукта

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9315562B2 (en) * 2010-11-26 2016-04-19 Tokyo Institute Of Technology High-strength collagen fiber membrane and a manufacturing method thereof
CN102676620A (zh) * 2011-12-20 2012-09-19 浙江省海洋开发研究院 一种高分子量鱿鱼皮胶原蛋白的制备方法
RU2614273C2 (ru) * 2014-11-24 2017-03-24 Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет инженерных технологий" (ФГБОУ ВО "ВГУИТ"). Способ получения коллагенового продукта

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SANKAR S. ET AL.: "Preparation and partial characterization of collagen sheet from fish (Lates calcarifer) scales", INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, vol. 42, no. 1, 2008, pages 6 - 9, XP022375897, DOI: 10.1016/j.ijbiomac. 2007.08.00 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114225112A (zh) * 2021-11-22 2022-03-25 江苏苏伯纳生物科技有限公司 一种脑脊液隔离修复膜的制备方法

Also Published As

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RU2737358C1 (ru) 2020-11-27

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