WO2021131057A1 - Récipient double isolé sous vide - Google Patents

Récipient double isolé sous vide Download PDF

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Publication number
WO2021131057A1
WO2021131057A1 PCT/JP2019/051562 JP2019051562W WO2021131057A1 WO 2021131057 A1 WO2021131057 A1 WO 2021131057A1 JP 2019051562 W JP2019051562 W JP 2019051562W WO 2021131057 A1 WO2021131057 A1 WO 2021131057A1
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WO
WIPO (PCT)
Prior art keywords
container
vacuum
liquefied gas
storage container
insulated double
Prior art date
Application number
PCT/JP2019/051562
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English (en)
Japanese (ja)
Inventor
和彦 新倉
早川　慎司
将仁 内藤
沙織 堀内
孝則 三分一
山田　隆哉
Original Assignee
株式会社エムダップ
ニプロ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 株式会社エムダップ, ニプロ株式会社 filed Critical 株式会社エムダップ
Priority to PCT/JP2019/051562 priority Critical patent/WO2021131057A1/fr
Priority to JP2021566756A priority patent/JPWO2021131057A1/ja
Publication of WO2021131057A1 publication Critical patent/WO2021131057A1/fr

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/38—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation

Definitions

  • the present invention relates to a vacuum-insulated double container that can be used as a container for transporting a sample in a frozen state or below freezing point.
  • a container body 66 having a vacuum heat insulating structure made of stainless steel is used, and the sample container is fixed in the container body 66 via the content fixture 64.
  • a tool 63 and a cryogenic liquefied gas adsorption / holding agent 61 are provided, respectively.
  • the sample container fixture 63 is formed with a plurality of sample container holding holes (not shown) for holding the sample container 62, and the outer shape thereof is formed to have the same shape as the horizontal cross-sectional shape inside the container body 66. Further, the sample container holding holes (not shown) are formed as a plurality of holes for holding the sample container 62, and penetrate in the vertical direction of the container body.
  • a plurality of cryogenic liquefied gas adsorption holders 61 are used in a laminated state, and the bottom surface of the cryogenic liquefied gas adsorption holder 61 is placed on the bottom of the container body 66 on the inner surface side. Further, a plurality of laminated cryogenic liquefied gas adsorption holders 61 are laminated so as to cover the periphery of the sample container 62 inserted into each of the plurality of sample container holding holes (not shown).
  • a content fixture between the outer peripheral surfaces of the sample container fixture 63 and the cryogenic liquefied gas adsorption / holding agent 61 and the inner peripheral surface of the container body 66 in order to ensure adhesion between the two. 64 is used.
  • the content fixture 64 is made of an elastic material such as polyethylene foam, and the inner peripheral surface of the content fixture 64 formed in a cylindrical shape allows the sample container fixture 64 to be formed.
  • the outer peripheral surfaces of 63 and the cryogenic liquefied gas adsorption / holding agent 61 are fixed in close contact with each other. Further, the outer peripheral surface of the content fixture 64 is configured to be in close contact with the inner peripheral surface of the container body 66.
  • the opening 65 of the container body 66 with the upper part open is covered with a screwed lid 67 so that it can be opened and closed. Further, a recess 68 for ventilation is formed on the outer peripheral surface of the opening 65 and / or the inner peripheral surface of the lid 67.
  • the venting recess 68 functions as a gap through which vaporized cryogenic liquefied gas can flow.
  • a heat insulating container 70 having a double-walled vacuum structure including an outer wall 70a and an inner wall 70b is used.
  • a storage material entrance / exit 73 is formed in the upper part of the heat insulating container 70, and a lid that can be opened / closed is provided in the storage material entrance / exit 73.
  • the heat insulating container 70 has a circular cross-sectional shape, and its peripheral wall has a vacuum structure surrounded by an outer wall 70a and an inner wall 70b.
  • the inside of the heat insulating container 70 (inside of the inner wall 70b) is hollow, and the hollow portion is provided with a storage portion 71 for storing storage items such as pharmaceuticals.
  • the storage portion 71 is composed of a stainless steel square cylinder with a bottom and an open top, and the side surface portion of the square cylinder is composed of a plate-shaped member 74 made of an angle material so as to surround the four corners of the storage portion.
  • a frame member (not shown) is welded to the outer peripheral portion near the upper end of the storage portion 71, and the bent portion (not shown) and the frame member (not shown) at the upper end of the plate-shaped member 74 are , It is integrated in a caulking structure by a fixed connecting member 75.
  • a waviness suppressing plate 72 is erected on the outer peripheral surface of the plate-shaped member 74, and the wavy suppressing plate 72 is arranged in the horizontal direction between the storage portion 71 and the inner wall 70b of the heat insulating container 70. It suppresses sloshing of liquid nitrogen stored in the space between the storage unit 71 and the inner wall 70b of the heat insulating container 70.
  • a space is formed between the upper part of the storage portion for accommodating the sample container 62 and the lid 67, and the vaporized ultra-low temperature liquefied gas is used for ventilation. It is configured to be discharged to the outside through a gap consisting of recesses 68. Therefore, with the passage of time, the concentration of the cryogenic liquefied gas adsorbed on the cryogenic liquefied gas adsorption / holding agent 61 decreases, which causes a problem that the low temperature holding time becomes short.
  • the sample container 62 from the middle portion to the upper end side is held by the sample container fixture 63 made of a resin material such as foamed polyethylene or polyurethane, the middle portion to the upper end portion side of the sample container 62 is poled. It cannot be cooled directly with cryogenic liquefied gas. Therefore, as the sample container 62, the lower end side in contact with the cryogenic liquefied gas adsorption holder 61 can be cooled, but a temperature gradient is generated between the lower end side and the middle part to the upper end side. I will let you.
  • cryogenic liquefied gas adsorption / holding agent 61 laminated on the side surface of the sample container 62 vaporizes the cryogenic liquefied gas, and the concentration of the cryogenic liquefied gas from the laminated upper cryogenic liquefied gas adsorption / holding agent 61 increases. It will decrease. Further, since the adsorbed cryogenic liquefied gas moves downward due to the influence of gravity, the cryogenic liquefied gas decreases on the upper side of the adsorption retainer 61. As described above, it is difficult to maintain the inside of the sample container 62 in a uniform temperature state.
  • the cryogenic liquefied gas adsorption / holding agent 61 has a laminated structure in which the cryogenic liquefied gas adsorption holder 61 is laminated.
  • the injected cryogenic liquefied gas is adsorbed from the cryogenic liquefied gas adsorption / holding agent 61 in the upper layer. Therefore, it takes a long time to be evenly adsorbed on all of the cryogenic liquefied gas adsorption and holding agents 61.
  • the vaporized cryogenic liquefied gas leaks to the outside through the opening of the storage portion, and the amount of the cryogenic liquefied gas used increases. Become. Moreover, when the amount of vaporization becomes large, it becomes difficult for the cryogenic liquefied gas adsorption / holding agent 61 to sufficiently absorb the cryogenic liquefied gas.
  • the container for both cryopreservation and transportation described in Patent Document 2 has a configuration in which liquid nitrogen is stored as it is in the space between the storage unit 71 and the inner wall 70b of the heat insulating container 70. Rippling (slozing) of nitrogen occurs, and it is necessary to suppress this. Therefore, the structure is provided with the rippling suppression plate 72, but as the vaporization of liquid nitrogen progresses, the liquid level height of the liquid nitrogen facing the rippling suppression plate 72 decreases, and rippling motion is likely to occur. Become. Moreover, the rippling motion becomes more intense with the vaporization of liquid nitrogen, and it becomes difficult to suppress the violent rippling (sloshing) by the suppression plate 72.
  • the heat insulating container 70 itself is largely moved on a mounting table or the like. Force will act.
  • the storage portion 71 has a square tubular shape, there is a risk of deforming the storage portion 71 itself when a concentrated load acts on the corners due to the energy of the rippling motion. In the worst case, there is a risk that the heat insulating container 70 will be damaged and that the sample will be damaged.
  • the gap space acts as a heat insulating space.
  • the cooling efficiency to the storage unit 71 will decrease.
  • the heat transfer effect of heat conduction through the fixed connecting member 75 is also reduced. Therefore, the cooling efficiency for cooling the storage unit 71 is low.
  • the stored sample can be efficiently frozen or cooled, and the sample can be effectively cryopreserved or transported below freezing point. .. Further, it is possible to shorten the adsorption time of the cryogenic liquefied gas adsorbed on the adsorbent, increase the adsorption amount of the adsorbent, and maintain an appropriate adsorption amount of the cryogenic liquefied gas for a long time.
  • the issue is to provide a heat-insulated double container.
  • the present invention is a vacuum-insulated double container in which an inner container is arranged in an outer container in a separated state and a sealed space between the outer container and the inner container is evacuated.
  • a connecting pipe that connects and fixes the opening edge of the inner lid that is fixed to the inner container and has an open central portion and the opening edge of the outer lid that is fixed to the outer container and has an open central portion.
  • a bottomed storage container arranged in the inner container, a plurality of partition plates erected on the outer peripheral surface of the storage container and separated from each other in parallel along the longitudinal direction of the storage container, and the contents.
  • the inner bottom surface of the container and the adsorbent block placed on each of the partition plates are provided.
  • the most important feature is that a plurality of intake / exhaust ports of the cryogenic liquefied gas adsorbed on each of the adsorbent blocks are formed at a plurality of locations of the storage container.
  • the vacuum-insulated double container according to the present invention has a configuration in which the inner container and the outer container are supported and connected by a connecting pipe, heat conduction from the inner container to the outer container via the connecting pipe is slow. It will be slow. Moreover, since a vacuum is set between the inner container and the outer container, the temperature inside the inner container drops slowly. Then, the temperature inside the inner container can be maintained so as not to drop for a long period of time. Further, if the outer peripheral surface of the connecting pipe is formed to be uneven, the strength of the connecting pipe in the longitudinal direction can be improved even if the connecting pipe is formed with a thin wall.
  • the cryogenic liquefied gas can be adsorbed on the adsorbent block.
  • the adsorption time can be shortened.
  • the adsorbent is configured as a plurality of adsorption blocks, and each adsorption block is placed on a partition plate and arranged separately, the plurality of adsorption blocks are laminated and integrated.
  • the adsorption amount of the cryogenic liquefied gas can be increased, and the adsorption time can be shortened.
  • the partition plate can prevent the cryogenic liquefied gas from moving downward, a stable temperature can be maintained for a long time.
  • the amount of the cryogenic liquefied gas decreases from the upper end side of the laminated adsorption blocks due to the vaporization of the cryogenic liquefied gas. Therefore, the entire surface of the storage container cannot be cooled in a uniform state.
  • the cryogenic temperature is low from the upper end side of each adsorption block due to the vaporization of the cryogenic liquefied gas. Even if the amount of liquefied gas is reduced, the side surface of the storage container can be cooled in a substantially uniform state.
  • FIG. 1 is a vertical cross-sectional view of a vacuum insulated double container.
  • FIG. 2 is a front view of the vacuum insulated double container.
  • FIG. 3 is a vertical cross-sectional view with the work carrier attached.
  • FIG. 4 is a perspective view of a main part of the laminated adsorbent block.
  • FIG. 5 is a vertical cross-sectional view of FIG. (Embodiment)
  • FIG. 6 is a front view of the work carrier and the vacuum insulated double vessel.
  • FIG. 7 is a vertical cross-sectional view of FIG. (Embodiment) FIG.
  • FIG. 8 is a perspective view of the work carrier and the vacuum insulated double container.
  • (Embodiment) 9 (A) is a front view of the storage container
  • FIG. 9 (B) is a perspective view of the storage container.
  • FIG. 10A is a front view of the storage container according to another configuration
  • FIG. 10B is a perspective view of the storage container.
  • FIG. 11 is a cross-sectional view of the biological sample transport container.
  • FIG. 12 is a perspective view including a partial cross section of the container for both cryopreservation and transportation.
  • the vacuum-insulated double container according to the present invention has a configuration other than that shown in the following examples, as long as it satisfies the technical idea of the present invention and can solve the problem of the present invention. It is not limited to the configuration described, and various changes can be made.
  • an inner container 10 having an open upper end is arranged in an outer container 3 having an open upper end, and a plurality of suction containers 10 are adsorbed in the inner container 10.
  • the structure is provided with a connecting pipe 20 for connecting the agent block 30, the storage container 25, and the outer container 3 and the inner container.
  • the bottom 6 of the outer container 3 is formed with an annular cylindrical portion that vertically supports the outer container 3 and a bottom plate portion that seals the inside of the outer container 3.
  • the bottom plate portion is formed in a curved surface shape protruding outward in a curved shape, and a vacuum suction portion 34 is formed at a desired portion of the bottom plate portion.
  • a bottom portion 6 is provided at the lower end portion of the outer container 3, and the bottom portion 6 includes an annular support portion in which the outer peripheral surface of the outer container 3 extends downward and a bottom surface portion that covers the bottom surface of the outer container 3. Is configured.
  • the bottom surface portion is formed in a curved surface shape that protrudes outward in a curved shape, and the annular support portion and the bottom surface portion are integrally fixed by the fixing portion 45.
  • An annular inner lid 11 having an open central portion is fixed to the upper end of the inner container 10 by a fixing portion 45, and the fixing portion 45 is integrally fixed by welding, brazing, and adhesion.
  • the bottom portion 12 of the inner container 10 is integrally formed by drawing or the like, and is formed in a curved shape protruding outward in a curved shape.
  • a thin aluminum plate can be wrapped so as to cover the entire outer peripheral surface of the inner container 10.
  • the thin-walled aluminum plate may be formed as a flat plate-like smooth surface, or may be formed as a rough surface such as wrinkled or satin-finished or grained.
  • the opening edge of the upper end of the outer lid 4 and the inner peripheral edge of the inner lid 11 are integrally fixed by the fixing portion 45 at the upper end and the lower end of the connecting pipe 20, respectively.
  • the space portion 21 surrounded by the outer lid 4, the outer container 3, the inner container 10, and the connecting pipe 20 is configured as a closed space portion.
  • the peripheral surface of the connecting pipe 20 can be formed in an uneven shape by using a thin metal, and by configuring in this way, the connecting pipe 20 can be connected even if the connecting pipe 20 is formed of the thin metal.
  • the surface strength of the pipe 20 is improved.
  • the connecting pipe 20 may be made of a thick pipe material in order to increase its surface strength, but the weight of the connecting pipe 20 increases and the thermal conductivity of the connecting pipe 20 increases. ..
  • the connecting pipe 20 formed in this way, the inner container 10 can be firmly supported and fixed to the outer container 4.
  • the outer container 3 and the inner container 10 are made of a thin metal material, and the outer container 3, the inner container 10 and the connecting pipe 20 are made of aluminum, an aluminum alloy or stainless steel. Further, the outer container 3 and the inner container 10 may be made of a thin plate having high physical strength and heat resistance.
  • the connecting pipe 20 may be made of a metal material such as a zinc alloy, a tin alloy, or a heat-resistant magnesium alloy, which has a lower thermal conductivity than aluminum, an aluminum alloy, or stainless steel.
  • the connecting pipe 20 is also made of the same material as the outer container 3 and the inner container 10. You can also do it.
  • a metal bottomed storage container 25 with an open upper end is stored in a state of being separated from the inner surface of the inner container 10.
  • a plurality of adsorbent blocks 30 are arranged on the bottom surface and the outer peripheral surface of the storage container 25, and the storage container 25 is a suction device arranged between the bottom surface of the storage container 25 and the bottom portion 12 of the inner container 10. Supported by agent block 30.
  • each partition plate 27 protruding toward the inner peripheral surface side of the inner container 10 are erected, and each partition plate 27 is along the longitudinal direction of the storage container 25. They are arranged in parallel with each other separated from each other. As shown in FIGS. 3, 4 and 5, an upwardly bent stopper piece 28 is formed on the tip end side of the partition plate 27, and the adsorbent block 30 placed on the partition plate 27 is positioned. The movement of the adsorbent block 30 on the partition plate 27 is restricted.
  • the partition plate 27 As the material of the partition plate 27, aluminum, aluminum alloy, or stainless steel is used as in the storage container 25.
  • the partition plate 27 can be integrally fixed to the outer peripheral surface of the storage container 25 by welding, brazing, and gluing. Further, although the illustrated example is omitted, it is also possible to wind the aluminum foil around each adsorbent block 30 to form the partition plate 27 and the stopper piece 28. In this case, it is desirable to form the adsorption port for the cryogenic liquefied gas on the wrapped aluminum foil so that the cryogenic liquefied gas supplied to the adsorbent block 30 can be adsorbed. Further, when the outer container 3 and the inner container 10 are made of a thin material having high physical strength and heat resistance, the partition plate 27 can also be made of the same material as the storage container 25.
  • the outer peripheral surface of the inner container 10 can be wrapped with a thin aluminum plate.
  • the outer peripheral surface of the inner container 10 made of metal can be made to have a metal laminated structure, and the radiant heat transfer from the outer peripheral surface of the inner container 10 can be minimized.
  • the outer peripheral surface of the inner container 10 can be wrapped with a thin-walled aluminum plate. ..
  • Each adsorbent block 30 can be arranged in close contact with the storage container 25. Further, as shown in FIG. 5, it is desirable that the stopper piece 28 of the partition plate 27 is arranged so that each adsorbent block 30 does not come into contact with the inner side surface of the inner container 10.
  • the storage container 25 is formed in a bottomed tubular shape, and the opening at the upper end is covered with a ring-shaped upper surface extending outward.
  • a plate 26 is provided.
  • the upper surface covering plate 26 can be integrally molded by bending the upper end portion of the storage container 25, or can be fixed to the upper end portion of the storage container 25 by welding, brazing, or adhesion.
  • the upper surface covering plate 26 can cover the upper surface of the adsorbent block 30 placed on the partition plate 27.
  • a plurality of intake / exhaust ports 33 for cryogenic liquefied gas are formed on the bottom surface of the top cover plate 26 and the storage container 25. Further, as shown in FIGS. 10A and 10B, a plurality of intake / exhaust ports 33 may be formed on the side surface of the storage container 25. The intake / exhaust port 33 may be formed above one-third of the total length of the storage container 25 and below one-third of the total length. Further, when the intake / exhaust port 33 is formed on the side surface of the storage container 25, it is desirable to open the intake / exhaust port 33 facing the upper end side of the adsorbent block 30 on the partition plate 27.
  • adsorbent used in the adsorbent block 30 an appropriate material can be used as long as it is a material capable of adsorbing the cryogenic liquefied gas.
  • zeolite, activated carbon, oil saw vent, glass wool and the like can be used as the adsorbent.
  • the plurality of adsorbent blocks 30 are arranged so as to cover the bottom surface side and the side surface side of the storage container 25.
  • the plurality of adsorbent blocks 30 arranged on the bottom surface side and the side surface side of the storage container 25 are arranged at equal intervals in the circumferential direction and the vertical direction.
  • a heat insulating tube 40 made of foamed resin may be installed so as to cover the entire inner surface of the connecting pipe 20.
  • a flange portion is formed at the upper end portion of the heat insulating tube 40, and the lid 2 of the work carrier 50, which will be described later, can be placed and fixed so as to be openable and closable.
  • the fixing between the flange portion of the heat insulating tube 40 and the lid body 2 of the work carrier 50 can be fixed by sandwiching the upper surface of the lid body 2 and the lower surface of the flange portion with a clip member, or by screwing. You can also do it. It can also be fixed using other known fixing methods.
  • a work carrier 50 that inserts and supports the sample in the storage container 25 is used.
  • the work carrier 50 holds the sample in the storage container 25 in a cryogenic state.
  • the work carrier 50 is provided at the lid 2 and the carrier guide 52 attached to the lower surface of the lid 2, the plate-shaped portion 54 attached downward to the lower surface of the carrier guide 52, and the lower end of the plate-shaped portion 54. It is configured to have a work storage section 51.
  • the lid 2 is detachably configured with a flange provided at the upper end of the heat insulating tube 40, and the upper surface of the lid 2 and the lower surface of the flange are sandwiched between the upper surface of the lid 2 and the lower surface of the flange by a clip or the like to bring them into close contact with each other. It can be held by letting it.
  • a screwed portion may be formed between the facing surfaces between the lid 2 and the flange portion.
  • the outer peripheral surface of the carrier guide 52 can be in close contact with the inner surface of the heat insulating tube 40 and also with the upper end side of the storage container 25.
  • the inside of the storage container 25 covered with the carrier guide 52 can be maintained in a sealed state.
  • the cryogenic liquefied gas vaporized from the adsorbent block 30 is exhausted to the outside through the heat insulating tube 40 and the carrier guide 52, and the inside of the inner container 10 is brought into a high pressure state by the vaporized cryogenic liquefied gas. Can be prevented.
  • the plate-shaped portion 54 is composed of a plate-shaped member having a predetermined width, and is arranged in a non-contact state with the storage container 25 together with the work storage portion 51. As the plate-shaped portion 54, even if an external force acts on the vacuum-insulated double container 1 and the vacuum-insulated double container 1 vibrates, the vibration can be absorbed by the long rectangular cross section of the plate-shaped portion 54. It is possible to prevent the work storage portion 51 arranged at the lower end portion from vibrating.
  • the work storage unit 51 is configured to have a storage space for storing a sample to be stored in the vacuum-insulated double container 1.
  • the lid 2, the carrier guide 52, the plate-shaped portion 54, and the work accommodating portion 51 constituting the work carrier 50 can be made of synthetic resin having high heat insulating properties.
  • the lid 2 and the plate-shaped portion 54 may be made of a rigid resin material.
  • the vacuum-insulated double container 1 As the sample to be stored in the vacuum-insulated double container 1, it is possible to use a sample that needs to be stored and transported in a frozen sample transport container, especially in the medical industry or research institutes, or a sample that needs to be transported below freezing point. it can. For example, tissues and cells of humans, animals and plants, biological structures, artificial biological structures such as cultured cells, and the like. Then, the vacuum-insulated double container 1 of the present invention can be used as a container used for transporting a sample that needs to be transported in a low temperature state.
  • cryogenic liquefied gas adsorbed on the adsorbent block 30 a gas that is stored in the vacuum-insulated double container 1 and transported according to the situation of the sample can be used.
  • a gas that is stored in the vacuum-insulated double container 1 and transported according to the situation of the sample can be used.
  • liquid nitrogen, liquid helium, liquefied argon, liquefied oxygen, liquefied carbon dioxide, or the like can be used as the cryogenic liquefied gas, but it may be appropriately selected depending on the condition of the sample to be transported in a frozen state. it can. [assembly]
  • the adsorbent block 30 is arranged on each of the plurality of partition plates 27 fixed to the sample storage container 25, and the top cover plate 26 is integrally fixed to the upper end portion of the sample storage container 25. To do. After the top cover plate 26 is integrally fixed to the upper end of the sample storage container 25, the adsorbent blocks 30 can be arranged on the plurality of partition plates 27, respectively.
  • the sample storage container 25 with the top cover plate 26 in which the adsorbent block 30 is placed on the bottom 12 of the inner container 10 before the inner lid 11 is fixed and the adsorbent block 30 is arranged on the peripheral surface is placed.
  • the sample storage container 25 is positioned and installed on the adsorbent block 30 placed on the bottom 12 of the inner container 10.
  • the peripheral edge of the lower end of the connecting pipe 20 is integrally fixed to the inner peripheral edge of the inner lid 11, and the inner lid 11 is integrally fixed to the inner container 10.
  • the peripheral edge of the upper end portion of the connecting pipe 20 is integrally fixed to the opening edge 5 at the upper end portion of the outer lid 4, and the lower end edge of the outer lid 4 is integrally fixed to the upper end outer peripheral edge of the outer container 3. To do.
  • the heat insulating tube 40 After that, insert the heat insulating tube 40 so that it is in close contact with the inner peripheral surface of the connecting tube 20 and the upper end of the sample storage container 25. As the heat insulating tube 40, the connecting pipe 20 can be inserted before being fixed to the inner lid 11.
  • the lid 2 provided with the work storage portion 51, the plate-shaped portion 54, and the work carrier 50 is inserted into the heat insulating tube 40, and the lid 2 and the flange portion formed at the upper end of the heat insulating tube 40 are attached and detached. By fixing it freely, the vacuum insulation double container 1 provided with the work carrier 50 can be completed.
  • the sample storage container 25 When storing the sample in the vacuum-insulated double container 1, remove the work carrier 50 from the vacuum-insulated double container 1 and inject the cryogenic liquefied gas through the inner peripheral surface of the heat-insulating tube 40.
  • the sample storage container 25 has the configurations shown in FIGS. 9 (a) and 9 (b)
  • the injected ultra-low temperature liquefied gas creates a gap between the lower end of the heat insulating tube 40 and the upper end of the sample storage container 25.
  • the sample is injected into each adsorbent block 30 through the plurality of intake / exhaust ports 33 formed on the upper surface covering plate 26 and the intake / exhaust ports 33 formed on the bottom surface of the sample storage container 25.
  • the injected cryogenic liquefied gas is discharged from each adsorbent block from the intake / exhaust ports 33 formed on the peripheral surface of the sample storage container 25. Infused into 30.
  • the intake / exhaust ports 33 formed on the peripheral surface of the sample storage container 25 are formed at positions corresponding to the upper end side of the adsorbent block 30 placed on each partition plate 27. .. Further, if necessary, the intake / exhaust port 33 can be formed on the bottom surface portion other than the peripheral surface of the sample storage container 25.
  • the adsorbent block 30 is configured in a block shape, and each adsorbent block 30 arranged on the peripheral surface of the sample storage container 25 is placed on the partition plate 27, and a plurality of intake / exhaust ports are provided. 33 is formed corresponding to the arrangement position of the adsorbent block 30.
  • the adsorption amount of the cryogenic liquefied gas can be set to an appropriate adsorption amount.
  • the adsorbent block 30 is configured in a block shape, and each adsorption block 30 arranged on the peripheral surface of the sample storage container 25 is partitioned. It is configured to be placed on the board 27.
  • the inner container 10 is suspended from the outer container 3 by using a connecting pipe 20 which is thin and has an uneven outer peripheral surface.
  • a heat insulating tube 40 is arranged on the inner surface of the connecting pipe 20.
  • the amount of heat transferred from the inner container 10 to the outside via the outer container 3 can be suppressed. Further, since the adsorption blocks 30 arranged on the peripheral surface of the sample storage container 25 are arranged on the partition plate 27 in a state of being separated in the vertical direction, an appropriate adsorption amount of extremely low liquefied gas can be obtained. Can be done.
  • the amount of the cryogenic liquefied gas adsorbed on each adsorption block 30 individually decreases from the upper end side, so that the entire surface of the sample storage container 25 is Can be maintained in a nearly uniform state.
  • the outer peripheral surface of the metal inner container 10 By wrapping the outer peripheral surface of the inner container 10 with a thin aluminum plate, the outer peripheral surface of the metal inner container 10 can be made into a metal laminated structure, and radiation is transmitted from the outer peripheral surface of the inner container 10. The heat can be minimized.
  • each adsorbent block 30 can be arranged in a state where each adsorbent block 30 does not come into contact with the inner surface of the inner container 10 by the stopper piece 28 of the partition plate 27.
  • an air layer that functions as a heat insulating layer is formed between each adsorbent block 30 arranged on the inner surface of the inner container 10 and the inner peripheral surface of the inner container 10. It is possible to prevent the cold air of the cryogenic liquefied gas adsorbed on each adsorbent block 30 from being transferred to the inner container 10.
  • the adsorption amount of the cryogenic liquefied gas is individually reduced from the upper end side of each adsorption block 30.
  • the entire surface of the sample storage container 25 can be maintained in a substantially uniform state.
  • the work carrier 50 as a fixing device can maintain the inside of the inner container 10 in a sealed state by the carrier guide 52 which is in close contact with the heat insulating tube 40 provided on the inner peripheral surface of the connecting pipe 20.
  • the lid 2 and the carrier guide 52 can be configured to be in close contact with the heat insulating tube 40 made of synthetic resin such as foamed resin, and the plate-shaped portion 54 and the lower end of the plate-shaped portion 54 provided at the lower end portion of the carrier guide 52.
  • the work storage portion 51 provided in the above is arranged in a non-contact state with respect to the sample storage container 25. With this configuration, even if an external force such as an impact acts on the vacuum-insulated double container 1, vibration or impact is less likely to be applied to the sample in the work storage portion 51.

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  • Filling Or Discharging Of Gas Storage Vessels (AREA)

Abstract

Récipient double isolé sous vide 1, comprenant des blocs adsorbants 30 formés dans une configuration de type bloc et des blocs adsorbants 30 respectifs agencés au niveau d'une surface circonférentielle d'un récipient de logement d'échantillon 25 de façon à être placés sur une plaque de séparation 27. Ce récipient double est en outre conçu de telle sorte qu'un récipient interne 10 est suspendu sur un récipient externe 3 à l'aide d'un tube de raccordement mince 20 ayant des évidements/saillies sur sa surface circonférentielle externe, et le tube de raccordement 20 comprend un tube d'isolation thermique 40 disposé sur sa surface interne. Dans ce récipient double, il est également possible de réduire au minimum la quantité de chaleur transférée depuis le récipient interne 10 vers l'extérieur par l'intermédiaire du récipient externe 3, et les blocs adsorbants respectifs 30 disposés sur la plaque de séparation 27 permettent d'assurer une quantité appropriée d'adsorption de gaz liquéfié cryogénique. En outre, ce récipient double est apte à maintenir la totalité de la surface du récipient de logement d'échantillon 25 dans un état refroidi presque uniformément.
PCT/JP2019/051562 2019-12-27 2019-12-27 Récipient double isolé sous vide WO2021131057A1 (fr)

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PCT/JP2019/051562 WO2021131057A1 (fr) 2019-12-27 2019-12-27 Récipient double isolé sous vide
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481779A (en) * 1983-06-22 1984-11-13 Union Carbide Corporation Cryogenic storage container
JP2007271279A (ja) * 2006-03-30 2007-10-18 Japan Agengy For Marine-Earth Science & Technology 凍結保存器
JP2010522863A (ja) * 2007-03-29 2010-07-08 エリック コニャール， 二重壁断熱球状物を備える輸送および／または保管装置

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481779A (en) * 1983-06-22 1984-11-13 Union Carbide Corporation Cryogenic storage container
JP2007271279A (ja) * 2006-03-30 2007-10-18 Japan Agengy For Marine-Earth Science & Technology 凍結保存器
JP2010522863A (ja) * 2007-03-29 2010-07-08 エリック コニャール， 二重壁断熱球状物を備える輸送および／または保管装置

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