WO2021121150A1 - 一种试剂盒 - Google Patents

一种试剂盒 Download PDF

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Publication number
WO2021121150A1
WO2021121150A1 PCT/CN2020/135697 CN2020135697W WO2021121150A1 WO 2021121150 A1 WO2021121150 A1 WO 2021121150A1 CN 2020135697 W CN2020135697 W CN 2020135697W WO 2021121150 A1 WO2021121150 A1 WO 2021121150A1
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Prior art keywords
flow channel
air
bin
storage tank
air inlet
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PCT/CN2020/135697
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English (en)
French (fr)
Inventor
郝书顺
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石家庄禾柏生物技术股份有限公司
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Publication of WO2021121150A1 publication Critical patent/WO2021121150A1/zh

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices

Definitions

  • the invention relates to a kit used when adding reagents.
  • the kit is a kind of test equipment commonly used in laboratories, which is used to store various liquid reagents used in some tests.
  • the tester needs to take out the reagent from the kit, the usual practice is to open the lid of the kit, and then use a syringe or dropper to suck a certain amount of the reagent, and then use it for the test operation. Because this process requires manual operation, if the tester is unskilled or careless, it is easy to contaminate his hands, body or test equipment. If the reagents used are corrosive or toxic, the consequences may be serious. Although there are some reagent kits on the market for adding reagents, these kits simply use air pressure to press out the reagents. The air inlet and the reagent reservoir are basically blown directly. Uniformity leads to unstable addition of reagents, and improper operation can also cause reagents to flow back from the air inlet.
  • the technical problem to be solved by the present invention is to provide a reagent kit with uniform air intake and stable liquid output.
  • a reagent kit which includes a box body, an air inlet provided on the box body, a liquid storage tank connected with the air inlet through an elongated flow channel, and a liquid storage tank connected with the liquid storage tank. Liquid outlet.
  • the elongated flow channel includes a first flow channel located in the lower part of the box body and a second flow channel arranged on the upper part of the box body and communicated with the first flow channel, one end of the first flow channel is connected with the air inlet, and the second flow channel is One end of the flow channel is in communication with the liquid storage tank.
  • a second gas storage compartment is provided at the other end of the first flow passage, and the second gas storage compartment is in communication with the second flow passage through a first air hole.
  • an overflow groove is provided at one end of the second flow path close to the liquid storage tank, and the overflow groove is communicated with the liquid storage tank through the third flow path.
  • a water absorbing sponge is arranged in the overflow groove.
  • a third gas storage compartment is provided at the other end of the second flow channel, the first gas hole is arranged in the third gas storage compartment, and the end of the first gas hole extends into the third gas storage compartment.
  • the box body is provided with an air intake bin communicating with the air inlet, and an air storage bin communicating with the air intake bin is provided below the air intake bin, and the air storage bin is in communication with the elongated flow channel, so The air intake bin and the air storage bin are communicated through a second air hole, and both ends of the second air hole extend into the inside of the air intake bin and the air storage bin respectively.
  • the gas storage bin is connected with a fourth gas storage compartment, and the fourth gas storage compartment is connected with the elongated flow channel.
  • the positive effect of the present invention is: the air inlet of the present invention is connected with the liquid storage tank through the elongated flow channel, and the gas will be fully mixed evenly during the flow of the elongated flow channel, and is not affected by the uniformity of the gas at the air inlet , To ensure that the liquid entering the liquid storage tank is uniform, so as to ensure that the reagent is discharged from the liquid storage tank evenly, which is beneficial to the measurement of the amount of discharged reagent.
  • these gas storage compartments can also store liquid.
  • the reagent in the liquid storage tank returns, it will be filled first.
  • these air storage compartments are filled, it will finally flow into the air inlet, which can effectively prevent the liquid from flowing back into the air inlet.
  • the ends of the first air hole and the second air hole both extend into the corresponding bin, and only when the liquid level in the bin is higher than the end, will it enter the next bin through the air hole, which can further prevent backflow.
  • Figure 1 is a schematic diagram of the structure of the present invention.
  • Figure 2 is a schematic diagram of the structure of the first flow channel of the present invention.
  • the present invention includes a box body 15, an air inlet 1 provided on the side of the box body 15, a liquid storage tank 8 communicating with the air inlet 1 through an elongated flow channel, and a liquid storage tank 8 8 Connected liquid outlet 14.
  • the liquid storage tank 8 is located inside the box body 15, and the liquid outlet 14 is installed on the side of the box body 15 and is located at the bottom of the liquid storage tank 8.
  • the elongated flow channel includes a first flow channel 11 located at the lower part of the box body 15 and a second flow channel 5 arranged on the upper part of the box body 15 and communicated with the first flow channel 11, and one end of the first flow channel 11 is connected to the air inlet 1 Connected, one end of the second flow channel 5 is connected to the liquid storage tank 8.
  • Both the first flow channel 11 and the second flow channel 5 adopt a continuous S-shaped design, which can further extend the gas transportation time in the flow channel, and there is sufficient time for the gas to be mixed and uniformly sent to the liquid storage tank 8.
  • an air inlet bin 2 communicating with the air inlet 1 is provided in the box body 15, and an air storage bin 16 communicating with the air inlet bin 2 is provided below the air inlet bin 2.
  • One end of the second flow channel 5 is in communication with the third gas storage compartment 17, and the other end is in communication with the overflow tank 6, and the overflow tank 6 is in communication with the liquid storage tank 8 through the third flow channel 7.
  • the first flow channel 11, the second flow channel 5 and the third flow channel 7 all adopt a continuous S-shaped design.
  • the time for gas to enter the liquid storage tank 8 from the air inlet 1 can be greatly extended, so that the incoming gas can be in these structures Fully mixing, even if the gas entering from the air inlet 1 is not uniform, after being transported for a long time through the above structure, it will be fully mixed and uniform when it enters the liquid storage tank 8.
  • connection between the second flow channel 6 and the third flow channel 7 and the overflow tank 6 are all located at the top of the overflow tank 6.
  • the part of the first air hole 4 located in the third gas storage compartment 17 extends into the third gas storage compartment 17, and its fixed top is higher than the bottom plate of the third gas storage compartment 17, when the reagent is filled with overflow
  • the tank 6 continues to flow back from the second flow channel 5, it needs to enter the third gas storage compartment 17.
  • the liquid level is higher than the end of the first gas hole 4, it can continue to flow from the first gas hole 4 to the second storage.
  • These structures can store the backflowing reagent when the backflow of the reagent occurs, effectively preventing the backflow of the reagent into the air inlet 1.
  • a water-absorbent sponge can be placed in the overflow tank 6 to adsorb the refluxed reagents, which can also further improve the reflux prevention effect.
  • the air intake bin 2 and the air storage bin 16 are communicated through a second air hole 3, and both ends of the second air hole 3 extend into the air intake bin 2 and the air storage bin 16 respectively.
  • the various flow channels and compartments of the present invention are separated by setting partitions inside or on the upper or lower top surface of the box body 15, and then formed by covering the plastic film on the partitions.
  • the volume is large, which will cause bulging when filling with gas.
  • a support plate 9 is provided in the liquid storage tank 8, and the top of the support plate 9 is also plastic-sealed with the plastic film.
  • liquid storage tanks there are two liquid storage tanks, both of which are communicated with the fourth gas storage compartment 10 through the same flow channel structure.
  • the two storage tanks When gas is charged from the air inlet 1, the two storage tanks will be simultaneously The reagent is discharged from the liquid tank.

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)

Abstract

一种试剂盒，其包括盒体（15）、设置在盒体（15）上的进气口（1）、通过细长流道与进气口（1）连通的储液槽（8）以及与储液槽（8）连通的出液口；试剂盒的进气口（1）通过细长流道与储液槽（8）连通，气体在细长流道的流动过程中会充分混合均匀，不受进气口（1）处气体是否均匀的影响，保证进入到储液槽（8）内的液体是均匀的，从而保证试剂从储液槽（8）内排出也是均匀的，有利于对排出试剂多少的计量。

Description

一种试剂盒 技术领域
本发明涉及一种添加试剂时使用的试剂盒。
 背景技术
试剂盒是一种实验室常用的试验器材，用于存放一些试验中所使用的各种各样的液体试剂。当在试验人员需要从试剂盒中取出试剂时，通常的做法是需要试验人员打开试剂盒的盖子，然后使用注射器或滴管吸取一定量的试剂，然后再用于试验操作。因为此过程需要人工操作，试验人员如果操作不熟练或不注意还容易污染到手上、身上或试验设备上。如果所使用的试剂具有一定的腐蚀性或毒性，后果就可能会很严重。现在市面上虽然有部分用于添加试剂的试剂盒，但是这些试剂盒都是简单的利用气压将试剂压出，进气口与试剂的储液槽基本是直吹方式，这样会因进气不均匀而导致试剂的添加量不稳定，同时操作不当还会造成试剂从进气口处回流的情况出现。
 技术问题
本发明所要解决的技术问题是提供一种进气均匀的出液稳定的试剂盒。
 技术解决方案
本发明所采用的技术方案是：一种试剂盒，其包括盒体、设置在盒体上的进气口、通过细长流道与进气口连通的储液槽以及与储液槽连通的出液口。
进一步的，所述细长流道包括位于盒体下部的第一流道以及设置在盒体上部并且与第一流道连通的第二流道，所述第一流道一端与进气口连通，第二流道的一端与储液槽连通。
进一步的，在所述第一流道的另一端设置有第二储气隔仓，所述第二储气隔仓与第二流道通过第一气孔连通。
进一步的，在所述第二流道靠近储液槽的一端设置有溢流槽，所述溢流槽通过第三流道与储液槽连通。
进一步的，在所述溢流槽内设置有吸水海绵。
进一步的，在所述第二流道的另一端设置有第三储气隔仓，第一气孔设置在第三储气隔仓内，并且第一气孔的端部伸入到第三储气隔仓的内部。
进一步的，所述盒体内设置有与进气口连通的进气仓，在进气仓的下方设置有与进气仓连通的储气仓，所述储气仓与细长流道连通，所述进气仓与储气仓通过第二气孔连通，所述第二气孔的两端分别伸入到进气仓与储气仓的内部。
进一步的，所述储气仓连通有第四储气隔仓，所述第四储气隔仓与细长流道连通。
 有益效果
本发明的积极效果为：本发明的进气口通过细长流道与储液槽连通，气体在细长流道的流动过程中会充分混合均匀，不受进气口处气体是否均匀的影响，保证进入到储液槽内的液体是均匀的，从而保证试剂从储液槽内排出也是均匀的，有利于对排出试剂多少的计量。
同时在流道内设置有多个储气隔仓，也可以实现使进入的气体变的均匀的作用，同时这些储气隔仓也可以储存液体，当储液槽内的试剂回流时，会首先灌满这些储气隔仓，最后才会流入到进气口内，可以有效防止液体回流至进气口内。并且第一气孔和第二气孔的端部均伸入到对应的仓内，只有当仓内液面高于该端部时才会通过气孔进入到下一个仓内，可以进一步防止倒流。
 附图说明
图1为本发明结构示意图。
图2为本发明第一流道结构示意图。
 本发明的实施方式
如附图1、2所示，本发明包括盒体15、设置在盒体15侧面上的进气口1、通过细长流道与进气口1连通的储液槽8以及与储液槽8连通的出液口14。储液槽8位于盒体15的内部，出液口14安装在盒体15的侧面上并且位于储液槽8的底部。
所述细长流道包括位于盒体15下部的第一流道11以及设置在盒体15上部并且与第一流道11连通的第二流道5，所述第一流道11一端与进气口1连通，第二流道5的一端与储液槽8连通。第一流道11与第二流道5均采用连续的S形设计，可以进一步延长气体在流道内的输送时间，有充分的时间去使气体混合均匀送到储液槽8内。
从气体在盒内的流动方向来看，在盒体15内设置有与进气口1连通的进气仓2，在进气仓2的下方设置有与进气仓2连通的储气仓16，在储气仓16的一侧有与之连通的第四储气隔仓10，第四储气隔仓10与第一流道11的一端连通，在第一流道11的另一端依次连通有第一储气隔仓12和第二储气隔仓13，在第二储气隔仓13远离第一储气隔仓12的一侧通过第一气孔4与第三储气隔仓17连通，第二流道5的一端与第三储气隔仓17连通，另一端与溢流槽6连通，溢流槽6通过第三流道7与储液槽8连通。第一流道11、第二流道5以及第三流道7均采用连续的S形设计。通过一系列的S形流道以及多个储气隔仓以及溢流槽的设计，可以大大延长气体从进气口1进入到储液槽8内的时间，使进入的气体可以在这些结构内充分混合，即使从进气口1进入的气体不均匀，通过上述结构的长时间运送后，在进入到储液槽8内时也会充分混合均匀。
第二流道6以及第三流道7与溢流槽6的连通处均位于溢流槽6的顶部，当储液槽8内的试剂回流时，试剂会先流入到溢流槽6内，只有将溢流槽6灌满后才会继续进入到第二流道5内。
同时第一气孔4位于第三储气隔仓17内的部分伸入到第三储气隔仓17的内部，其定顶部高于第三储气隔仓17的底板，当试剂灌满溢流槽6继续从第二流道5回流时，需进入到第三储气隔仓17内，当液面高于第一气孔4的端部后才可以从第一气孔4继续流入到第二储气隔仓13内。
这些结构都可以当发生试剂回流的情况时，将回流的试剂存储起来，有效防止试剂回流至进气孔1内。
更进一步的，在溢流槽6内可以放置吸水海绵，将回流的试剂进行吸附，也可以进一步的提高防回流效果。
所述进气仓2与储气仓16通过第二气孔3连通，所述第二气孔3的两端分别伸入到进气仓2与储气仓16的内部。
本发明的各个流道以及隔仓等均是通过在盒体15的内部或上部或下顶面设置隔板分隔成的，再通过在隔板上覆盖塑封膜而成，由于储液槽8的容积较大，在充入气体时会造成鼓包，为了避免此现象，在储液槽8内设置有支撑板9，支撑板9的顶部同样与塑封膜进行塑封。
在本发明的实施例中，储液槽有两个，均通过相同的流道结构与第四储气隔仓10连通，当从进气口1充入气体的时候，会同时从两个储液槽内排出试剂。

Claims (8)

  1. 一种试剂盒，其特征在于其包括盒体（15）、设置在盒体（15）上的进气口（1）、通过细长流道与进气口（1）连通的储液槽（8）以及与储液槽（8）连通的出液口（14）。
  2. 根据权利要求1所述的一种试剂盒，其特征在于所述细长流道包括位于盒体（15）下部的第一流道（11）以及设置在盒体（15）上部并且与第一流道（11）连通的第二流道（5），所述第一流道（11）一端与进气口（1）连通，第二流道（5）的一端与储液槽（8）连通。
  3. 根据权利要求2所述的一种试剂盒，其特征在于在所述第一流道（11）的另一端设置有第二储气隔仓（13），所述第二储气隔仓（13）与第二流道（5）通过第一气孔（4）连通。
  4. 根据权利要求2所述的一种试剂盒，其特征在于在所述第二流道（5）靠近储液槽（8）的一端设置有溢流槽（6），所述溢流槽（6）通过第三流道（7）与储液槽（8）连通。
  5. 根据权利要求4所述的一种试剂盒，其特征在于在所述溢流槽（6）内设置有吸水海绵。
  6. 根据权利要求3所述的一种试剂盒，其特征在于在所述第二流道（5）的另一端设置有第三储气隔仓（17），第一气孔（4）设置在第三储气隔仓（17）内，并且第一气孔（4）的端部伸入到第三储气隔仓（17）的内部。
  7. 根据权利要求1所述的一种试剂盒，其特征在于所述盒体（15）内设置有与进气口（1）连通的进气仓（2），在进气仓（2）的下方设置有与进气仓（2）连通的储气仓（16），所述储气仓（16）与细长流道连通，所述进气仓（2）与储气仓（16）通过第二气孔（3）连通，所述第二气孔（3）的两端分别伸入到进气仓（2）与储气仓（16）的内部。
  8. 根据权利要求7所述的一种试剂盒，其特征在于所述储气仓（16）连通有第四储气隔仓（10），所述第四储气隔仓（10）与细长流道连通。
PCT/CN2020/135697 2019-12-20 2020-12-11 一种试剂盒 WO2021121150A1 (zh)

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CN111308111B (zh) * 2019-12-20 2024-08-27 石家庄禾柏生物技术股份有限公司 一种试剂盒
CN112455872A (zh) * 2020-11-23 2021-03-09 石家庄禾柏生物技术股份有限公司 一种带有气液隔离陷阱的试剂盒
CN112526153A (zh) * 2020-11-23 2021-03-19 石家庄禾柏生物技术股份有限公司 试剂盒

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