WO2021086048A2 - Dispositif de régulation de débit de médicament liquide - Google Patents

Dispositif de régulation de débit de médicament liquide Download PDF

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Publication number
WO2021086048A2
WO2021086048A2 PCT/KR2020/014901 KR2020014901W WO2021086048A2 WO 2021086048 A2 WO2021086048 A2 WO 2021086048A2 KR 2020014901 W KR2020014901 W KR 2020014901W WO 2021086048 A2 WO2021086048 A2 WO 2021086048A2
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WO
WIPO (PCT)
Prior art keywords
chemical liquid
valve
control device
flow path
liquid flow
Prior art date
Application number
PCT/KR2020/014901
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English (en)
Korean (ko)
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WO2021086048A3 (fr
Inventor
김용현
Original Assignee
김용현
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020200041584A external-priority patent/KR102472316B1/ko
Application filed by 김용현 filed Critical 김용현
Priority to JP2022525393A priority Critical patent/JP7420934B2/ja
Priority to EP20880587.9A priority patent/EP4052740A4/fr
Priority to IL292619A priority patent/IL292619A/en
Priority to US17/772,460 priority patent/US20220355027A1/en
Priority to CN202080076437.7A priority patent/CN114641326A/zh
Publication of WO2021086048A2 publication Critical patent/WO2021086048A2/fr
Publication of WO2021086048A3 publication Critical patent/WO2021086048A3/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body

Definitions

  • the present disclosure relates to an apparatus for regulating a flow rate of a chemical liquid.
  • a drug solution injection device for injecting a liquid drug solution (for example, an injection solution) to a patient.
  • a liquid drug solution for example, an injection solution
  • the chemical solution in a predetermined storage space passes through a passage connected to the patient (eg, a chemical solution injection tube and an inner space of an injection needle), and flows into the patient's body.
  • a device including a drug delivery tube that forms a capillary flow path so that a drug solution is prevented from being injected into the body of a patient at a time and the drug is gradually injected into the body for a considerable time.
  • the conventional chemical injection device having a capillary flow path is configured to reduce the flow rate of the chemical solution, but is not configured to control the flow rate of the chemical solution administered to the patient. Therefore, it is difficult to control the flow rate of the drug solution administered to the patient according to the patient's condition or the type of disease.
  • Embodiments of the present disclosure improve or solve at least some of the problems of a conventional chemical injection device.
  • a plurality of embodiments provide an apparatus for controlling a flow rate of a chemical solution configured to adjust the flow rate of the chemical solution when injecting the chemical solution into the human body.
  • Embodiments according to an aspect of the present disclosure relate to a chemical liquid flow rate control device.
  • the chemical liquid flow control device having a chemical liquid flow path for guiding the flow of the chemical liquid, the chemical liquid flow path is joined by an inflow flow path into which the chemical liquid flows, a plurality of branch flow paths branching from the inflow flow path, and a plurality of branch flow paths, and the chemical liquid flows out Includes outflow flow paths.
  • a chemical liquid flow control apparatus includes: a plurality of transfer pipes configured to correspond to a plurality of branch flow paths, each forming a capillary flow path constituting at least a part of one of the plurality of branch flow paths; And a valve member configured to selectively open and close the plurality of branch flow paths to control a flow rate of the chemical liquid flowing out through the flow path.
  • the plurality of transfer pipes may include at least two transfer pipes configured to flow the chemical liquid at different flow rates.
  • the chemical liquid flow control device may further include a plurality of pressing members configured to correspond to a plurality of branch flow paths, and each configured to be movable.
  • the valve member may be configured to be pressed or released as the pressing member moves, so as to selectively open and close a plurality of branch flow paths.
  • the chemical liquid flow rate control device may further include an operation member configured to move the pressing member.
  • a plurality of recesses formed to be spaced apart from each other so as to accommodate a plurality of pressing members may be formed in the operation member.
  • the valve member is elastically restored and may be configured to urge the pressing member in the recessed direction of the recess.
  • the actuating member may be configured to operate by moving the recess in a direction transverse to the recessed direction of the recess. As the operation member operates, a plurality of pressing members may be selectively received in the plurality of recesses.
  • valve member may be configured to open a corresponding branch flow path while the pressing member is accommodated in the recess.
  • the chemical liquid flow control device may further include a guide member disposed between the valve member and the plurality of pressing members and guiding the movement of the plurality of pressing members.
  • the chemical liquid flow rate control device is configured to correspond to a plurality of branch flow paths, a plurality of pressing members configured to be movable, respectively; An operation member configured to move the pressing member; And an operation member detachably engaged with the operation member and configured to operate the operation member in a state engaged with the operation member.
  • the operation member may be formed with an engaging portion, and the operation member may be formed with a corresponding engaging portion in which the engaging portion is received.
  • valve member may be configured to be elastically deformed by being pressed, and to be elastically restored by being released from the pressure.
  • the chemical liquid flow control device may further include a valve housing covered by a valve member and formed with a plurality of valve spaces each forming a part of a corresponding one of the plurality of branch flow paths.
  • a plurality of valve holes may be formed in the valve housing to communicate with each of the plurality of valve spaces and capillary passages of the plurality of transfer pipes.
  • the chemical liquid flow rate control device may further include a plurality of pressing members configured to correspond to a plurality of branch flow paths and configured to be movable, respectively.
  • the valve member may be configured to close the valve hole when pressed by the pressing member.
  • connection hole constituting a part of the outlet flow path may be formed in any one of the plurality of valve spaces.
  • a communication flow path for communicating two adjacent valve spaces among a plurality of valve spaces may be formed.
  • a connection hole constituting a part of the outlet flow path may be formed in any one of the plurality of valve spaces. In a state in which the valve member opens the valve hole and in a state in which the valve member closes the valve hole, the connection hole and the communication flow path may be configured to remain open.
  • the valve member may include a plurality of protrusions that protrude toward a plurality of valve spaces and are configured to close corresponding branch flow paths, respectively.
  • the chemical liquid flow control device may further include a plurality of pressing members configured to correspond to a plurality of branch flow paths, and each configured to be movable.
  • the valve member may be provided with a plurality of seating portions disposed opposite the plurality of protrusions and on which the plurality of pressing members are seated.
  • the chemical liquid flow rate control device may further include an air passing filter disposed in the inlet passage or the outlet passage.
  • a medical staff such as a doctor may conveniently adjust the flow rate (ie, flow rate) of the drug solution administered to a patient.
  • the flow rate (ie, flow rate) of the drug solution administered to the patient may be adjusted to various values.
  • FIG. 1 is a perspective view of a chemical liquid flow control device according to an embodiment of the present disclosure.
  • FIG. 2 is a plan view of the chemical liquid flow rate control device shown in FIG. 1.
  • FIG. 3 is a cross-sectional view taken along the line III-III shown in FIG. 2 and shows an example of a direction in which a chemical solution flows.
  • FIG. 4 is a cross-sectional view taken along the line III-III shown in FIG. 2 and shows another example of a direction in which a chemical liquid flows.
  • FIG. 5 is an exploded perspective view of the chemical liquid flow control device shown in FIG. 1.
  • FIG. 6 is an exploded perspective view showing the chemical liquid flow rate control device shown in FIG. 3 from a different angle.
  • FIG. 7 is an exploded perspective view showing the chemical liquid flow rate control device shown in FIG. 3 from another angle.
  • FIG. 8 is a perspective view showing a cross section taken along line VIII-VIII shown in FIG. 2.
  • FIG. 9 is a cross-sectional view taken along the line VIII-VIII shown in FIG. 2.
  • FIGS. 5 to 7 are bottom perspective views showing the operation member shown in FIGS. 5 to 7;
  • FIG. 12 is a view showing an example of flow rate control according to the operation of the chemical liquid flow rate control device according to an embodiment of the present disclosure.
  • FIG. 13 is a view showing another example of flow rate control according to the operation of the chemical liquid flow rate control device of FIG. 12.
  • FIG. 14 is a diagram showing still another example of flow rate control according to the operation of the chemical liquid flow rate control device of FIG. 12.
  • FIG. 15 is a diagram showing still another example of flow rate control according to the operation of the chemical liquid flow rate control device of FIG. 12.
  • FIG. 16 is a diagram showing still another example of flow rate control according to the operation of the chemical liquid flow rate control device of FIG. 12.
  • Embodiments of the present disclosure are illustrated for the purpose of describing the technical idea of the present disclosure.
  • the scope of the rights according to the present disclosure is not limited to the embodiments presented below or specific descriptions of these embodiments.
  • a component when referred to as being "connected” or “connected” to another component, a component can be directly connected to or can be connected to another component, or a new other component It is to be understood that it may or may be connected via an element.
  • FIG. 1 is a perspective view of a chemical liquid flow control device according to an embodiment of the present disclosure.
  • 2 is a plan view of the chemical liquid flow rate control device shown in FIG. 1.
  • the chemical liquid flow control apparatus 100 has a chemical liquid flow path 10 for guiding the flow of the chemical liquid.
  • the drug solution is a drug that can be administered to a patient for treatment of the patient and is made of a liquid.
  • the drug solution flow rate control device 100 is configured to adjust the flow rate of the drug solution to be administered to the patient.
  • the chemical liquid flow rate control device 100 may include cases 20 and 30.
  • the chemical liquid flow control device 100 may include housings 181 and 170 forming at least a part of the chemical liquid flow path 10.
  • the cases 20 and 30 may include a first case 20 and a second case 30 coupled to each other.
  • the housings 181 and 170 may include a flow path-forming housing 181 and a valve housing 170 that are coupled to each other.
  • the housings 181 and 170 are formed with a hole 11a that is one end of the chemical liquid flow path 10 and a hole 13a that is the other end of the chemical liquid flow path 10.
  • 3 is a cross-sectional view taken along the line III-III shown in FIG. 2 and shows an example of a direction in which a chemical solution flows.
  • 4 is a cross-sectional view taken along the line III-III shown in FIG. 2 and shows another example of a direction in which a chemical liquid flows.
  • the chemical liquid flow path 10 includes a first flow path 11, a second flow path 13, and a plurality of branches connecting the first flow path 11 and the second flow path 13. It includes a flow path 12.
  • the first flow path 11 is an inflow flow path through which the chemical liquid is introduced
  • the second flow path 13 is an outflow flow path through which the chemical liquid flows out.
  • the chemical liquid flows in through the first flow path 11 and flows out through the second flow path 13 through at least one of the plurality of branch flow paths 12.
  • the second flow path 13 is an inflow flow path through which the chemical liquid is introduced
  • the first flow path 11 is an outflow flow path through which the chemical liquid flows out.
  • the chemical liquid flows in through the second flow path 13 and flows out through the first flow path 11 through at least one of the plurality of branch flow paths 12. That is, a flow path through which the chemical solution flows may be understood as an inflow channel, and a flow channel through which the chemical solution flows out may be understood as an outflow channel.
  • the plurality of branch flow paths 12 diverge from the inflow flow path, and the chemical liquid joined from the plurality of branch flow paths 12 flows out through the outflow flow path.
  • the number of the plurality of branch flow paths may be n.
  • 'N' referred to throughout this description means'a natural number greater than or equal to 2'.
  • the number of the plurality of pressing members 130 to be described later may be n, and the plurality of branch flow paths may be opened and closed by each of the pressing members 130.
  • the hole 11a formed outside the flow path forming housing 181 may form a part of the first flow path 11.
  • the first flow path 11 may be configured by a filter mechanism 180 to be described later.
  • the first flow path 11 is formed by sequentially connecting the hole 11a and the flow path formed in the filter mechanism 180.
  • the hole 13a formed outside the valve housing 170 may form a part of the second flow path 13.
  • the connection hole 173 to be described later may constitute a part of the second flow path 13.
  • the second flow path 13 is formed by sequentially connecting the connection hole 173 and the hole 13a.
  • the n holes 14a, 14b, and 14c of the sealer 14 may each form a part of any one of the n branch flow paths.
  • Each of the capillary flow paths 110p of the n transfer pipes 110a, 110b, and 110c may form a part of any one corresponding to each of the n branch flow paths.
  • Each of the n holes 175a, 175b, and 175c of the connector 175 may form a part of any one corresponding to each of the n branch flow paths.
  • each of the n valve holes 172a, 172b, and 172c may form a part of any one corresponding to each of the n branch flow paths.
  • Each of the n valve spaces 171a, 171b, and 171c may form a part of any one corresponding to each of the n branch flow paths.
  • Each of the n-1 communication flow paths 174a and 174b to be described later may form a part of any one of the n-1 branch flow paths that are part of the n branch flow channels.
  • the plurality of branch flow paths 12 include a first branch flow path, a second branch flow path, and a third branch flow path.
  • the first branch flow path is a first hole 14a of the sealer 14, a capillary flow path 110p formed in the first transfer pipe 110a, and a first hole 175a of the connection pipe 175 ,
  • the first valve hole 172a, the first valve space 171a, and the first communication flow path 174a may be sequentially connected to each other to be formed.
  • the second branch flow path includes a second hole 14b of the sealer 14, a capillary flow path 110p formed in the second transfer pipe 110b, a second hole 175b of the connection pipe 175, and a second valve.
  • the hole 172b and the second valve space 171b may be sequentially connected to each other to be formed.
  • the third branch flow path includes a third hole 14c of the sealer 14, a capillary flow path 110p formed in the third transfer pipe 110c, a third hole 175c of the connection pipe 175, and a third valve.
  • the hole 172c, the third valve space 171c, and the second communication passage 174b may be sequentially connected to each other to be formed.
  • each of the plurality of holes of the flow path forming housing 181 may constitute a part of each of the first branch flow path, the second branch flow path, and the third branch flow path.
  • the chemical liquid flow rate control device 100 may further include a sealer 14 disposed between the first flow path 11 and the branch flow path 12.
  • the sealer 14 may be formed of a material such as rubber.
  • the sealer 14 may be a rubber packing, and a passage branching from the first passage 11 to the branch passage 12 may be formed in the sealer 14.
  • the chemical solution may be guided to pass through the capillary flow path 110p of the branch flow path 12 through the sealer 14.
  • FIG. 5 is an exploded perspective view of the chemical liquid flow control device shown in FIG. 1.
  • 6 is an exploded perspective view showing the chemical liquid flow rate control device shown in FIG. 3 from a different angle.
  • 7 is an exploded perspective view showing the chemical liquid flow rate control device shown in FIG. 3 from another angle.
  • the chemical liquid flow rate control apparatus 100 includes a plurality of transfer pipes 110 and a valve member 120.
  • the plurality of transfer pipes 110 are configured to correspond to the plurality of branch flow paths 12.
  • the plurality of transfer pipes 110 form a capillary flow path 110p constituting at least a part of a corresponding one of the plurality of branch flow paths 12.
  • the transfer pipe 110 may include a polymer microtube.
  • the plurality of transfer pipes 110 may be n.
  • the n number of transfer pipes 110 may have capillary flow paths 110p having different inner diameters (or cross-sectional areas).
  • the number of the plurality of transfer pipes 110 may be variously determined according to the precision of the flow rate control of the chemical liquid flow rate control device 100.
  • each of the capillary flow paths 110p corresponding to the plurality of transfer pipes 110 may be determined differently according to the precision of the flow rate control of the chemical liquid flow control device 100.
  • the plurality of conveying pipes 110 may have an inner diameter of about 0.04mm to 0.08mm. Accordingly, by selectively opening and closing a plurality of capillary flow paths 110p set to different flow rates, flow rate control is facilitated and various flow rates can be adjusted.
  • the plurality of transfer pipes 110 may include at least two transfer pipes configured to flow the chemical liquid at different flow rates.
  • the plurality of branch flow paths 12 are composed of a first branch flow path, a second branch flow path, and a third branch flow path
  • the plurality of transfer pipes 110 are the first transfer pipes 110a. ), a second transfer pipe (110b), and a third transfer pipe (110c).
  • the first transfer pipe 110a, the second transfer pipe 110b, and the third transfer pipe 110c may be configured to pass 1.5cc, 1.0cc, and 0.5cc of chemicals per hour, respectively.
  • the valve member 120 is configured to selectively open and close the plurality of branch flow paths 12 to control the flow rate of the chemical liquid flowing out through the second flow path 13.
  • the valve member 120 functions as a valve mechanism connecting the branch passage 12 and the second passage 13.
  • FIG. 8 is a perspective view showing a cross section taken along line VIII-VIII shown in FIG. 2.
  • 9 is a cross-sectional view taken along the line VIII-VIII shown in FIG. 2.
  • the chemical liquid flow rate control device 100 is configured to correspond to a plurality of branch flow paths 12, and a plurality of pressing members 130 configured to be movable, respectively. ) May be further included.
  • the pressing member 130 has a spherical shape and follows a direction perpendicular to the longitudinal direction RL of the plurality of conveying pipes 110 (ie, branch flow paths) (for example, the vertical direction UD in FIG. 3 ). It is configured to change the relative distance to the valve member 120 as it moves.
  • the pressing member 130 may have a rod shape having a hemispherical shape at both ends.
  • the plurality of pressing members 130 may include a first pressing member 130a, a second pressing member 130a corresponding to each of the first conveying pipe 110a, the second conveying pipe 110b, and the third conveying pipe 110c. It may include a pressing member (130b) and a third pressing member (130c).
  • the chemical liquid flow rate control device 100 may further include an operation member 140 configured to move the plurality of pressing members 130.
  • the operation member 140 may be located on the opposite side of the valve member 120 with respect to the pressing member 130.
  • the operation member 140 has a plate shape and is configured to rotate along a rotation center along a direction perpendicular to the longitudinal direction RL of the plurality of conveying pipes 110 (eg, the vertical direction UD). As the operation member 140 rotates, at least one of the plurality of pressing members 130 may move relative to the valve member 120.
  • the operation member 140 is described and illustrated as having a disk shape, the operation member 140 may have a polygonal plate shape.
  • FIGS. 5 to 7 are bottom perspective views showing the operation member shown in FIGS. 5 to 7;
  • the operation member 140 is formed with a plurality of recesses 141 spaced apart from each other so that a plurality of pressing members 130 are accommodated, and the valve member 120 ) Is elastically restored and may be configured to press the pressing member 130 in the recessed direction (eg, upward direction) of the recess 141.
  • the plurality of recesses 141 are formed on the bottom surface of the operation member 140 and are concave in the opposite direction (eg, upward direction) of the valve member 120 with respect to the pressing member 130.
  • the plurality of recesses 141 may be arranged to be spaced apart from each other along the circumferential direction along the rotation center.
  • the number and formation position of the plurality of recesses 141 may be determined according to the number of the plurality of transfer pipes 110 and the precision of the flow rate control of the chemical liquid flow control device 100.
  • the operation member 140 is configured to be operated by moving the recess 141 in a direction transverse to the recessed direction of the recess 141, and as the operation member 140 operates, a plurality of The pressing member 130 may be selectively accommodated in the plurality of recesses 141.
  • the recessed direction of the recess 141 means an upper direction among the vertical directions (UD), and the direction crossing the recessed direction of the recess 141 is the longitudinal direction (RL) and the plurality of conveying pipes 110 It may mean a direction along a plane formed by the arranged front and rear directions FR. That is, as the plate-shaped operation member 140 rotates along the rotation center, the plurality of pressing members 130 are selectively accommodated in the plurality of recesses 141 to open and close the plurality of branch flow paths 12. I can.
  • the valve member 120 may be configured to open a corresponding branch flow path 12 in a state in which the pressing member 130 is accommodated in the recess 141. That is, the valve member 120 is configured to open the branch flow path 12 corresponding to the pressing member 130 accommodated in the recess 141 among the plurality of pressing members 130. On the contrary, the valve member 120 closes the branch flow path 12 corresponding to the pressing member 130 not accommodated in the recess 141 in a state where the pressing member 130 is not accommodated in the recess 141. It is composed.
  • the valve member 120 is depressurized and the branch flow path 12 is opened, and the pressing member 130 is accommodated in the recess 141.
  • the branch flow path 12 is closed.
  • the chemical liquid flow rate control device 100 is disposed between the valve member 120 and the plurality of pressing members 130, and further includes a guide member 150 for guiding the movement of the plurality of pressing members 130.
  • the guide member 150 is configured to cover the valve member 120 and is coupled to the valve housing 170.
  • the guide member 150 serves to guide the pressing member 130 to move in the vertical direction (UD), and to space the plurality of pressing members 130 from each other along the front-rear direction FR.
  • a plurality of guide holes 151 are formed in the guide member 150 to be spaced apart from each other along the front-rear direction FR and hold the plurality of pressing members 130.
  • the guide member 150 is a vertical direction (UD) equal to or greater than the distance in which the plurality of pressing members 130 move in the vertical direction (UD) between the pressing state and the pressing state of the valve member 120 It can have a thickness along the line.
  • the plurality of guide holes 151 may be n.
  • the plurality of guide holes 151 may include a first guide hole 151a and a second pressure corresponding to each of the first pressing member 130a, the second pressing member 130b, and the third pressing member 130c.
  • a guide hole 151b and a third guide hole 151c may be included.
  • the chemical liquid flow rate control device 100 may further include an operation member 140 and an operation member 160.
  • the operation member 140 may be configured to move the pressing member 130 or may be configured to operate the valve member 120.
  • the operation member 160 is configured to operate the operation member 140 in a state engaged with the operation member 140.
  • the operation member 160 may be configured to adjust the flow rate of the chemical solution by rotating the operation member 140.
  • a shaft hole 140a for supporting rotation of the operation member 140 is formed in the center of the operation member 140.
  • an engaging portion 161 is formed on the operation member 160, and a corresponding engaging portion 142 may be formed in the operation member 140 by receiving the engaging portion 161. That is, the corresponding engaging portion 142 may be formed to be concave so that the engaging portion 161 can be accommodated.
  • the engaging portion 161 and the corresponding engaging portion 142 may have a shape complementary to each other.
  • the engaging portion 161 may have a star-shaped or polygonal planar shape, and the corresponding engaging portion 142 may be formed to be concave downward to correspond to the planar shape of the engaging portion 161.
  • the operation member 160 may further include a handle portion 162 protruding upward from the engaging portion 161. The user can easily rotate the operation member 140 by gripping and rotating the handle part 162.
  • the operation member 160 may be detachably coupled from a part of the operation member 140 of the chemical liquid flow rate control device 100.
  • a doctor in charge or a nurse in charge may be used in combination with the chemical liquid flow control device 100 when the operation member 160 is carried or stored in a certain place and then the flow rate of the chemical liquid needs to be adjusted. Accordingly, it is possible to prevent a patient or an unauthorized user from arbitrarily manipulating the operation member 160 to adjust the flow rate of the chemical solution. That is, the operation member 160 may function as a key configured to rotate the operation member 140 by being coupled to the chemical liquid flow control device 100 when it is necessary to adjust the flow rate of the chemical liquid.
  • the valve member 120 may be configured to be elastically deformed by being pressed, and to be elastically restored by being released from the pressure.
  • the valve member 120 may be made of a material capable of elastic deformation and restoration of elasticity, such as a rubber material.
  • the valve member 120 is configured to be elastically deformed by the pressing of the pressing member 130 to close the corresponding branch flow path 12, and the pressing member 130 is When accommodated in the recess 141, it may be configured to open the corresponding branch flow path 12 by providing an elastic restoring force to move the pressing member 130 upward.
  • the chemical liquid flow rate control device 100 may further include a valve housing 170 in which a plurality of valve spaces 171 are formed.
  • the plurality of valve spaces 171 are configured to be covered by the valve member 120.
  • the valve member 120 functions as a cover or sealing member that prevents the chemical liquid held in the valve space 171 from flowing upward.
  • Each of the plurality of valve spaces 171 constitutes a part of a corresponding one of the plurality of branch flow paths 12.
  • the plurality of valve spaces 171 are formed to be concave in the lower direction of the vertical direction UD and are arranged in a row in the front-rear direction FR.
  • the plurality of concave valve spaces 171 form a space closed by the valve member 120 as a sealing member to be included in a part of the corresponding branch flow path 12 among the plurality of branch flow paths 12.
  • the plurality of valve spaces 171 may be n.
  • the plurality of valve spaces 171 may include a first valve space 171a and a second valve corresponding to each of the first transfer pipe 110a, the second transfer pipe 110b, and the third transfer pipe 110c. It may include a valve space 171b and a third valve space 171c.
  • the valve housing 170 may include a plurality of connection pipes 175 to which a plurality of transfer pipes 110 forming the capillary flow path 110p are connected.
  • a plurality of transfer pipes 110 may be connected to be inserted into the plurality of connection pipes 175 or a plurality of connection pipes may be inserted into the plurality of transfer pipes 110.
  • the plurality of connection pipes 175 may be n.
  • the plurality of connection pipes 175 may include a first hole 175a and a second hole into which each of the first transfer pipe 110a, the second transfer pipe 110b, and the third transfer pipe 110c is inserted. It may include (175b) and a third hole (175c).
  • a plurality of valve holes 172 communicating with each of the plurality of valve spaces 171 and the capillary flow paths 110p of the plurality of transfer pipes 110 may be formed in the valve housing 170.
  • the plurality of valve holes 172 may be formed at the bottom of the corresponding plurality of valve spaces 171.
  • the plurality of valve holes 172 communicate with each of the plurality of connection pipes 175.
  • the chemical liquid introduced through the plurality of connection pipes 175 is temporarily held in the valve space 171 through the valve hole 172, or the chemical liquid temporarily held in the valve space 171 is through the valve hole 172 It may flow through a plurality of connection pipes 175.
  • the plurality of valve holes 172 may be n.
  • the plurality of valve holes 172 may include a first valve hole 172a, a second valve communicating with the first transfer pipe 110a, the second transfer pipe 110b, and the third transfer pipe 110c. It may include a hole 172b, and a third valve hole 172c.
  • each of the first valve hole 172a, the second valve hole 172b, and the third valve hole 172c may be opened or closed. Accordingly, the flow rate of the chemical liquid flowing in the chemical liquid flow path 10 may be adjusted.
  • the valve member 120 may be configured to close the valve hole 172 when pressed by the pressing member 130.
  • the valve member 120 is made of an elastically deformable material such as rubber, when the pressing member 130 moves downward and presses the valve member 120 downward, the valve member 120 It is elastically deformed within (171). Accordingly, the elastically deformed portion of the valve member 120 may contact the valve hole 172 to close the valve hole 172.
  • a connection hole 173 to which the second flow path 13 is connected may be formed in any one of the plurality of valve spaces 171.
  • the plurality of valve spaces 171 communicate with the second flow path 13 through the connection hole 173, and the plurality of branch flow paths 12 join through the connection hole 173.
  • the chemical liquid flowing from the second flow path 13 is temporarily held in the valve space 171 through the connection hole 173, or the chemical liquid temporarily held in the valve space 171 is the second through the connection hole 173 It flows through the flow path 13.
  • a communication flow path 174 communicating two valve spaces 171 adjacent to each other among the plurality of valve spaces 171 may be formed.
  • the plurality of valve holes 172 and the connection holes 173 are in communication with each other through a communication flow path 174. That is, the valve hole 172 of the valve space 171 in which the connection hole 173 is not formed communicates with the connection hole 173 via the communication flow path 174, and the valve space in which the connection hole 173 is formed ( The valve hole 172 of the 171 is directly communicated with the connection hole 173 without passing through the communication flow path 174.
  • the plurality of communication flow paths 174 may be n-1.
  • the communication channel 174 is formed by covering the groove formed in the valve housing 170 by the valve member 120, but in another embodiment not shown, the communication channel 174 is formed in the valve housing 170. It can also be configured alone.
  • the chemicals located in each of the n valve spaces 171a, 171b, and 171c may be collected into one valve space 171b by a communication flow path 174.
  • the communication flow path 174 is formed to connect between the first valve space 171a and the second valve space 171b, the first communication flow path 174a, the second valve space 171b, and the third A second communication flow path 174b formed to connect between the valve spaces 171c may be included.
  • the connection hole 173 and the communication flow path 174 Can be configured to remain open. That is, regardless of the state in which the valve member 120 opens or closes the valve hole 172, the connection hole 173 and the communication flow passage 174 are configured to always remain open. Accordingly, the valve hole 172 of the valve space 171 in which the connection hole 173 is not formed is closed, and the valve hole 172 of the valve space 171 in which the connection hole 173 is not formed is opened. Also, the valve hole 172 of the valve space 171 in which the connection hole 173 is not formed may communicate with the connection hole 173 through the communication flow path 174. As a result, the chemical liquid can flow along the communicated path.
  • the valve member 120 may include a plurality of protrusions 121 configured to protrude toward the plurality of valve spaces 171 and close corresponding branch flow paths 12, respectively. At least some of the plurality of protrusions 121 protrude toward the plurality of valve spaces 171 and are accommodated in the valve space 171. Therefore, by reducing the moving distance of the pressing member 130 along the vertical direction UD, it is possible to achieve a downsizing of the chemical liquid flow rate control device 100. In addition, since the flow rate of the chemical liquid temporarily held by the valve space 171 can be kept low due to the plurality of protrusions 121, the initial time for administering the chemical liquid can be shortened.
  • the plurality of protrusions 121 may be n.
  • the plurality of protrusions 121 may include a first protrusion 121a and a second protrusion corresponding to each of the first pressing member 130a, the second pressing member 130b, and the third pressing member 130c. 121b), and a third protrusion 121c.
  • each of the first protrusion 121a, the second protrusion 121b, and the third protrusion 121c is a first valve hole 172a, a second valve hole 172b, and a third valve hole 172c.
  • Each can be configured to open or close.
  • the valve member 120 may be provided with a plurality of seating portions 122 disposed opposite the plurality of protrusions 121 and on which the plurality of pressing members 130 are seated. Since the plurality of pressing members 130 are seated on the plurality of seating portions 122, each of the plurality of pressing members 130 is accurately positioned in each of the plurality of valve spaces 171, so that the valve hole 172 is surely closed. It is composed.
  • the plurality of seating portions 122 may be formed to be concave in the downward direction.
  • the plurality of pressing members 130 may be configured such that the radius of curvature of the plurality of pressing members 130 coincide with the radius of curvature of the plurality of receiving parts 122 so that the plurality of pressing members 130 are accurately mounted on the plurality of receiving parts 122.
  • the plurality of seating portions 122 may be n.
  • the plurality of seating portions 122 may include a first seating portion 122a, a second seating portion 122a corresponding to each of the first pressing member 130a, the second pressing member 130b, and the third pressing member 130c. It may include a seating portion (122b) and a third seating portion (122c).
  • the chemical liquid flow control device 100 may include a first case 20 and a second case 30 configured to cover the plurality of transfer pipes 110 and the valve member 120. .
  • the first case 20 and the second case 30 may be configured to be coupled to each other.
  • a plurality of transfer pipes 110 and valve housing 170 are configured to be fixed to the first case 20.
  • the first flow path 11 and the second flow path 13 are configured to protrude outward from the first case 20 and the second case 30 and are fixed by the first case 20 and the second case 30.
  • a manipulation hole 30a may be formed in the second case 30 to expose the manipulation member 160. After the operation member 160 is coupled with the operation member 140 by inserting the operation member 160 through the operation hole 30a, the position of the operation member 140 may be changed.
  • the operation member 140 may be configured to change its position by rotating, or may be configured to change its position through movement other than rotation (eg, sliding).
  • the chemical liquid flow rate control device may further include an air passing filter (eg, filter mechanism 180) disposed in the first flow path 11.
  • the filter mechanism 180 removes gas contained in the chemical liquid flowing along the chemical liquid flow path 10 and residual gas dissolved in the chemical liquid. Accordingly, it is possible to prevent the capillary flow path from being blocked by microscopic air bubbles.
  • the filter mechanism 180 includes a flow path forming housing 181; Boundary filter 182; Filter cap 183; And at least one air passing filter.
  • the flow path forming housing 181 may be referred to as a filter housing.
  • the flow path forming housing 181 may be disposed on the chemical liquid flow path 10 and may form at least a part of the first flow path 11.
  • the chemical liquid flowing through the first flow path 11 (for example, the embodiment of FIG. 3) or the chemical liquid flowing through the first flow path 11 (for example, the embodiment of FIG. 4) is a flow path forming housing ( 181).
  • An inner hole 181b may be formed in the flow path forming housing 181.
  • a portion where n branch flow paths start may be formed in the inner hole 181b, and a portion where n branch flow paths start may be formed by the sealer 14.
  • the sealer 14 is inserted into the inner hole 181b.
  • the first flow path 11 may include a filter flow path 181c.
  • the filter flow path 181c may be disposed inside the flow path forming housing 181.
  • the chemical liquid may sequentially flow through the hole 11a and the filter flow passage 181c, or sequentially flow through the filter flow passage 181c and the hole 11a.
  • the boundary filter 182 may be disposed on the first flow path 11.
  • the boundary filter 182 may be disposed in the flow path forming housing 181.
  • the boundary filter 182 may be made of a hydrophilic material.
  • the boundary filter 182 is configured such that the boundary filter 182 acts as a pressure boundary surface between an upstream channel portion and a downstream channel portion based on the boundary filter 182 when the chemical solution is wetted.
  • the boundary filter 182 may have different internal pressures.
  • the boundary filter 182 may be configured in at least one of a mesh structure and a fiber structure.
  • the boundary filter 182 may additionally have a function of filtering impurities.
  • the filter cap 183 is air-tight and water-tight coupled to the flow path-forming housing 181.
  • the filter cap 183 forms a passage through which air contained in the chemical liquid introduced through the first passage 11 flows out.
  • the filter cap 183 may form at least one vent hole (not shown) positioned at a point where the air passage is connected to the external space.
  • At least one air passing filter is made of a hydrophobic material and is configured to filter air in the chemical liquid flow path 10.
  • the air passing filter blocks the passage of the chemical liquid and serves to pass air.
  • the air passing filter may be disposed on the filter cap 183.
  • the air passing filter may include a first air passing filter 184 disposed at a boundary between the air passage and the filter passage 181c.
  • the air passing filter may further include a second air passing filter 185 disposed on the air passage.
  • the air passing filter includes a first air passing filter 184 and a second air passing filter 185 which are sequentially disposed on a passage of air from the flow path forming housing 181 toward the filter cap 183 can do.
  • the first air passing filter 184 is disposed inside the filter cap 183
  • the second air passing filter 185 is disposed on the opposite side of the first air passing filter 184 based on the filter cap 183. I can.
  • the second air passing filter 185 is configured to pass air that has passed through the first air passing filter 184. Accordingly, the second air passing filter 185 serves to prevent the internal chemical liquid from flowing out even when the pores or adhesive portions of the first air passing filter 184 are damaged.
  • the second air passing filter 185 may be formed by processing the same material as the first air passing filter 184 or a porous plastic material.
  • the second air passing filter 185 may be formed such that a hydrophobic porous plastic resin material fills a partial cross-sectional area of the air passage.
  • the material of the second air pass filter 185 is from Porex Corporation (Website: https://www.porex.com) of Fairburn, GA 30213, GA, USA. Can be obtained. There is a product available under the name Porex Hydrophobic Vents of forex Corporation, which is made from a material of polyethyle polytetrafluoroethylene.
  • the filter spacer 186 is disposed inside the filter cap 183 to contact the first air passing filter 184.
  • the filter spacer 186 is configured to suppress or prevent the first air passing filter 184 from bending toward the flow path forming housing 181 due to the pressure of the chemical solution.
  • a plurality of protrusions may be formed on a surface of the filter spacer 186 facing the first air passing filter 184 (eg, a surface facing the flow path forming housing 181). Accordingly, the air passing through the first air passing filter 184 may flow through the gap between the plurality of protrusions.
  • the protrusion of the filter spacer 186 may have an embossed shape or a pleated shape.
  • a plurality of protrusions having an embossed shape or a pleat shape are formed on the side opposite to the side where the filter spacer 186 faces the first air passing filter 184 (for example, the side facing the filter cap 183). Can be.
  • An arrangement groove into which the filter spacer 186 is inserted may be formed in the filter cap 183.
  • the filter cap 183 may include a protrusion that separates the side surface of the filter spacer 186 from the inner surface of the filter cap 183.
  • the filter cap 183 may include a protrusion that separates the rear surface of the filter spacer 186 from the inner surface of the filter cap 183. Through this, air may smoothly flow between the filter spacer 186 and the inner surface of the filter cap 183.
  • An air hole constituting a part of the air passage may be formed in the filter cap 183.
  • the chemical liquid flow rate control device 100 may further include a shaft 190.
  • the shaft 190 serves to support the operation member 140 to rotate with respect to the valve housing 170 and the flow path forming housing 181.
  • a first shaft guide part 176 may be formed in the valve housing 170
  • a second shaft guide part 181a may be formed in the flow path forming housing 181.
  • the first shaft guide portion 176 and the second shaft guide portion 181a are coupled to each other to form a circular groove.
  • a portion of the shaft 190 is configured to pass through the shaft hole 140a of the operation member 140 and be coupled to the first shaft guide portion 176 and the second shaft guide portion 181a.
  • the first shaft guide portion 176 and the second shaft guide portion 181a may have a complementary shape so as to be relatively rotatable by engaging with each other.
  • 12 to 16 are views showing an example of flow rate control according to the operation of the chemical liquid flow rate control device according to an embodiment of the present disclosure. 12 to 16 together show a plan view and a cross-sectional view according to the operation of the chemical liquid flow control device, and a plurality of recesses 141 formed on the bottom surface of the operation member 140 are hidden around the operation member 160 It is shown as.
  • first conveying pipe (110a), the second conveying pipe (110b), and the third conveying pipe (110c) are described as an example of a case where the chemical solution of 1.5cc, 1.0cc, and 0.5cc per hour passes. do.
  • the operation member 160 when the operation member 160 is positioned, the first pressing member 130a is accommodated in the recess 141 of the operation member 140, and the second pressing member 130b and the second pressing member 130b are 3
  • the pressing member 130c abuts against the bottom surface 143 of the operation member 140.
  • the first protrusion 121a is spaced apart from the first valve hole 172a, and the first valve hole 172a is opened.
  • the second pressing member 130b and the third pressing member 130c elastically deform the second protruding portion 121b and the third protruding portion 121c of the valve member 120, so that the second valve hole 172b and the third The valve hole 172c is closed.
  • the first transfer pipe 110a communicates with the connection hole 173 through the opened first valve hole 172a.
  • the flow rate of the chemical liquid that can flow through the chemical liquid flow rate control device 100 becomes 0.5 cc per hour corresponding to the flow rate of the first transfer pipe 110a.
  • the second pressing member 130b is accommodated in the recess 141 of the operation member 140, and the first pressing member 130a and the first 3
  • the pressing member 130c abuts against the bottom surface 143 of the operation member 140.
  • the second protrusion 121b of the valve member 120 is spaced apart from the second valve hole 172b, and the second valve hole 172b is opened.
  • the first pressing member 130a and the third pressing member 130c elastically deform the first protrusion 121a and the third protrusion 121c of the valve member 120, so that the first valve hole 172a and the third The valve hole 172c is closed.
  • the second transfer pipe 110b communicates with the connection hole 173 through the opened second valve hole 172b.
  • the flow rate of the chemical liquid that can flow through the chemical liquid flow rate control device 100 becomes 1.0 cc per hour corresponding to the flow rate of the second transfer pipe 110b.
  • the third pressing member 130c is accommodated in the recess 141 of the operation member 140, and the first pressing member 130a and the first 2 The pressing member 130b abuts against the bottom surface 143 of the operation member 140.
  • the third protrusion 121c of the valve member 120 is spaced apart from the third valve hole 172c, and the third valve hole 172c is opened.
  • the first pressing member 130a and the second pressing member 130b elastically deform the first protrusion 121a and the second protrusion 121b of the valve member 120, so that the first valve hole 172a and the second The valve hole 172b is closed.
  • the third transfer pipe 110c communicates with the connection hole 173 through the opened third valve hole 172c.
  • the flow rate of the chemical liquid that can flow through the chemical liquid flow rate control device 100 becomes 1.5 cc per hour corresponding to the flow rate of the third transfer pipe 110c.
  • the first pressing member 130a and the third pressing member 130c are accommodated in the recess 141 of the operation member 140, and 2
  • the pressing member 130b abuts against the bottom surface 143 of the operation member 140.
  • Each of the first protrusion 121a and the third protrusion 121c of the valve member 120 is spaced apart from the first valve hole 172a and the third valve hole 172c, 3
  • the valve hole 172c is opened.
  • the second pressing member 130b elastically deforms the second protruding portion 121b of the valve member 120, so that the second valve hole 172b is closed.
  • each of the first transfer pipe 110a and the third transfer pipe 110c communicates with the connection hole 173 through the opened first valve hole 172a and the third valve hole 172c, respectively.
  • the flow rate of the chemical solution that can flow through the chemical solution flow rate control device 100 becomes 2.0 cc per hour corresponding to the total flow rate of the first transfer pipe 110a and the third transfer pipe 110c.
  • the first pressing member 130a, the second pressing member 130b, and the third pressing member 130c are It is received in the recess 141.
  • Each of the first protrusion 121a, the second protrusion 121b, and the third protrusion 121c of the valve member 120 is a first valve hole 172a, a second valve hole 172b, and a third valve hole ( 172c), the first valve hole 172a, the second valve hole 172b, and the third valve hole 172c are opened. Accordingly, the first valve hole 172a, the second valve hole 172b, and the third valve each of the first transfer pipe 110a, the second transfer pipe 110b, and the third transfer pipe 110c are opened.
  • the flow rate of the chemical liquid that can flow through the chemical liquid flow rate control device 100 is 3.0 per hour corresponding to the total flow rate of the first transfer pipe 110a, the second transfer pipe 110b, and the third transfer pipe 110c. becomes cc.

Abstract

Selon un aspect de la présente invention, les modes de réalisation concernent un dispositif de régulation de débit de médicament liquide. Le dispositif de régulation de débit de médicament liquide comporte un trajet d'écoulement de médicament liquide pour guider l'écoulement de médicament liquide, le trajet d'écoulement de médicament liquide comprenant un trajet d'écoulement d'entrée par lequel le médicament liquide s'écoule pour entrer, une pluralité de trajets d'écoulement de dérivation qui bifurquent à partir du trajet d'écoulement d'entrée, et un trajet d'écoulement de sortie par lequel le médicament liquide s'écoule pour sortir après convergence à partir de la pluralité de trajets d'écoulement de dérivation. Le dispositif de régulation de débit de médicament liquide selon un mode de réalisation représentatif comprend : une pluralité de tuyaux de transport qui correspondent respectivement à la pluralité de trajets d'écoulement de dérivation, et qui forment chacun un trajet d'écoulement capillaire qui constitue au moins une partie d'un trajet correspondant parmi la pluralité de trajets d'écoulement de dérivation ; et un élément de vanne conçu pour ouvrir ou fermer sélectivement la pluralité de trajets d'écoulement de dérivation pour réguler le débit du médicament liquide qui s'écoule pour sortir à travers le trajet d'écoulement de sortie.
PCT/KR2020/014901 2019-11-01 2020-10-29 Dispositif de régulation de débit de médicament liquide WO2021086048A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2022525393A JP7420934B2 (ja) 2019-11-01 2020-10-29 薬液流量調節装置
EP20880587.9A EP4052740A4 (fr) 2019-11-01 2020-10-29 Dispositif de régulation de débit de médicament liquide
IL292619A IL292619A (en) 2019-11-01 2020-10-29 Medical fluid flow control device
US17/772,460 US20220355027A1 (en) 2019-11-01 2020-10-29 Medicinal liquid flow control apparatus
CN202080076437.7A CN114641326A (zh) 2019-11-01 2020-10-29 药液流量调节装置

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20190138896 2019-11-01
KR10-2019-0138896 2019-11-01
KR10-2020-0041584 2020-04-06
KR1020200041584A KR102472316B1 (ko) 2019-11-01 2020-04-06 약액 유량 조절 장치

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Publication number Priority date Publication date Assignee Title
CA2498899C (fr) * 2002-09-19 2011-04-19 I-Flow Corporation Dispositif permettant de reguler selectivement le debit d'un fluide
KR101068806B1 (ko) * 2008-09-26 2011-10-04 에이스메디칼 주식회사 고정식 약액 공급량 조절기와 임의식 약액 공급량 조절기가구비된 약액 공급장치.
KR20140049836A (ko) * 2012-10-18 2014-04-28 주식회사 우영메디칼 약액 유량 제어장치
KR20140111245A (ko) * 2014-08-27 2014-09-18 주식회사 우영메디칼 약액 유량 제어장치
KR101638969B1 (ko) * 2014-09-30 2016-07-12 주식회사 우영메디칼 멀티형 약액 유량 제어장치 및 이를 포함하는 약액 주입기
KR102085515B1 (ko) * 2018-02-27 2020-03-05 주식회사 이화메디텍 약액 공급 조절장치 및 이를 구비한 주사액 주입장치

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