WO2021014688A1 - Dispositif de transport d'échantillon - Google Patents

Dispositif de transport d'échantillon Download PDF

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Publication number
WO2021014688A1
WO2021014688A1 PCT/JP2020/012858 JP2020012858W WO2021014688A1 WO 2021014688 A1 WO2021014688 A1 WO 2021014688A1 JP 2020012858 W JP2020012858 W JP 2020012858W WO 2021014688 A1 WO2021014688 A1 WO 2021014688A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample
transport
magnetic material
sample holder
electromagnet
Prior art date
Application number
PCT/JP2020/012858
Other languages
English (en)
Japanese (ja)
Inventor
邦昭 鬼澤
渡辺　洋
Original Assignee
株式会社日立ハイテク
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社日立ハイテク filed Critical 株式会社日立ハイテク
Priority to CN202080052018.XA priority Critical patent/CN114126995B/zh
Priority to EP20843376.3A priority patent/EP4005954A4/fr
Priority to JP2021534536A priority patent/JP7314278B2/ja
Priority to US17/628,650 priority patent/US20220276276A1/en
Publication of WO2021014688A1 publication Critical patent/WO2021014688A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G54/00—Non-mechanical conveyors not otherwise provided for
    • B65G54/02—Non-mechanical conveyors not otherwise provided for electrostatic, electric, or magnetic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/02—Identification, exchange or storage of information
    • B01L2300/021—Identification, e.g. bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G2201/00—Indexing codes relating to handling devices, e.g. conveyors, characterised by the type of product or load being conveyed or handled
    • B65G2201/02—Articles
    • B65G2201/0235—Containers
    • B65G2201/0261—Puck as article support
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0401—Sample carriers, cuvettes or reaction vessels
    • G01N2035/0406—Individual bottles or tubes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0477—Magnetic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0489—Self-propelled units

Definitions

  • the present invention relates to a sample transport device.
  • a sample processing system that automatically analyzes biological samples such as blood and urine is generally a sample pretreatment device that inserts, opens, centrifuges, dispenses, and labels samples such as blood collected for testing. And an automatic analyzer that analyzes the sample processed by the sample pretreatment device. Since there are various types of processing and analysis, each unit is composed of a plurality of units, and each unit is connected by a transport line to transport the sample between the units.
  • a bar code label for identifying an individual is affixed to a sample container such as a blood collection tube, and the bar code label can be read by a bar code reader.
  • a sample container such as a blood collection tube
  • the bar code label can be read by a bar code reader.
  • the sample holder that holds the sample container has a circular horizontal cross section for smooth transportation, it is difficult to specify the circumferential position of the barcode label. Therefore, the barcode label is read by rotating the sample holder and the sample container with a dedicated rotating device.
  • Patent Document 1 discloses that "the barcode scanning unit scans the barcode label during the rotational movement of the rotating device" (paragraph 0049).
  • Patent Document 1 if a rotating device is separately provided on the transport line and the sample holder is rotated each time a scan is performed, the device becomes large and the processing capacity decreases.
  • An object of the present invention is to provide a sample transport device in which a sample identifier can be read while suppressing an increase in size of the device and a decrease in processing capacity.
  • the present invention comprises a sample holder that holds a sample container and is provided with a transport magnetic material, and a plurality of sample holders that carry the sample holder by attracting or repelling the transport magnetic material.
  • the magnetic flux center of the transport magnetic material was eccentric with respect to the central axis of the sample container.
  • a sample transport device in which a sample identifier can be read while suppressing an increase in size of the device and a decrease in processing capacity.
  • the schematic diagram which shows the sample transport device which concerns on Example 1 of this invention The schematic diagram which shows the arrangement of the magnetic material provided in the sample holder which concerns on Example 1 of this invention.
  • FIG. 1 is a schematic view showing a sample transport device of this embodiment.
  • the sample transfer device of the present embodiment is applied to a transfer line connecting between the pretreatment device and the analyzer, a transfer line connecting each unit in the pretreatment device, and the like.
  • the pretreatment device is a device that performs pretreatment such as centrifugation, opening, and dispensing of a biological sample (sample) collected from a patient in a blood collection tube, and the analyzer is used for pretreatment. It is a device that analyzes and processes the sample.
  • the sample transport device of this embodiment holds the sample container 101 and is arranged under the sample holder 103 provided with the transport magnetic body 201 and the transport surface 301, and is a transport magnetic body. It is provided with a plurality of electromagnets 310, 320, 330 that convey the sample holder 103 by attracting or repelling 201.
  • Each electromagnet 310, 320, 330 is composed of a core and a winding wound around the core, and when a current is supplied to the winding, a magnetic field is generated on the transport surface 301. Is.
  • a bar code label 102 on which a bar code is printed as an identifier in which the sample identification information is coded is attached.
  • the material attached to the sample container 101 is not limited to a barcode, and may be another identifier such as a two-dimensional code or RFID.
  • the sample holder 103 can carry one sample container 101 and has a plurality of magnetic materials. As this magnetic material, a permanent magnet such as neodymium or ferrite is desirable, but other magnets or soft magnetic materials may also be used.
  • FIG. 2 is a schematic view showing the arrangement of magnetic materials provided in the sample holder 103.
  • the sample holder 103 of this embodiment has a circular horizontal cross section, and on the bottom surface thereof, a transport magnetic body (magnet) 201, a positioning magnetic body (magnet) 202, and the like. Is provided.
  • the magnetic flux center of the transport magnetic material 201 is eccentric with respect to the center of the sample holder 103, that is, the position of the central axis of the sample container 101.
  • the magnetic flux center of the positioning magnetic body 202 substantially coincides with the position of the central axis of the sample container 101.
  • the center of the transport magnetic body 201 is spatially deviated from the central axis of the sample container 101, but even if the center axis of the sample container 101 is spatially coincident with the center axis, the transport magnetism
  • the position of the magnetic flux center of the body 201 may be at a position magnetically deviated from the central axis of the sample container 101.
  • the sample transport device supplies a current to the windings of the adjacent electromagnet 310 toward a predetermined position and transports a magnetic field that attracts the transport magnetic body 201. Generate on surface 301. Then, when the sample holder 103 reaches the electromagnet 310, the sample transfer device further supplies an electric current to the windings of the adjacent electromagnet 330 to generate a magnetic field that attracts the transport magnetic body 201. By repeating this, the sample holder 103 can be transported to a predetermined position. In addition to the attractive force of the electromagnet at the transport destination, the repulsive force of the electromagnet at the transport source may be used to obtain the thrust of the sample holder 103.
  • the transport magnetic material 201 is attracted or repelled by the magnetic field on the transport surface 301, and is always at a position closer to the transport destination than the center of the sample holder 103. Therefore, even if the sample holder 103 has a circular horizontal cross section, the side surface on which the transport magnetic body 201 is located can always be positioned at the head in the transport direction. That is, the orientation of the sample holder 103 at the end of transportation can be set to a fixed orientation.
  • the sample container 101 is arranged so that the barcode label 102 is located on the side of the magnetic material 201 for transportation. It is arranged in advance with respect to the sample holder 103. Then, when the transportation to the predetermined position is completed, the surface of the sample container 101 with the barcode label 102 is in a state of facing the barcode reader. Therefore, it is possible to read the barcode without rotating the sample holder 103 or the like by separately providing a rotating device, and it is possible to suppress an increase in size of the device and a decrease in processing capacity.
  • a barcode reader identifier reader
  • the bar code reader irradiates the bar code label 102 attached to the sample container 101 with light from a light source and detects the light information obtained from the bar code to obtain the sample information contained in the bar code. It is something to read.
  • the reading method is not particularly limited, and for example, either the CCD method or the laser method can be used.
  • FIG. 3 is a schematic view of a horizontal cross section showing the sample holder 103 and the electromagnets around it.
  • the sample holder 103 is on the electromagnet 310.
  • the center of the sample holder 103 is fixed in the vicinity directly above the electromagnet 310.
  • the sample holder 103 moves its center position. While maintaining the position, the mounting surface of the transport magnetic body 201 faces the side where the electromagnet 311 is located.
  • the transport magnetic material is similarly obtained.
  • the mounting surface of 201 faces the side with the electromagnet 312. After that, the sample holder 103 rotates on the electromagnet 310 by sequentially repeating the same operations as those of the electromagnets 313,314,315,316,317,318,311.
  • the first electromagnet directly below the positioning magnetic body 202 attracts the positioning magnetic body 202 and the second electromagnet around the first electromagnet.
  • the sample holder 103 can be rotated by sequentially sucking the transporting magnetic material 201. That is, since the sample holder 103 can be rotated without separately providing a rotating device, it is possible to suppress the increase in size of the device.
  • the second electromagnet is not limited to the one located adjacent to the first electromagnet, and an electromagnet located away from the first electromagnet may be used.
  • the sample holder 103 may be rotated by using the force for repelling the transport magnetic body 201, but the direction in which the repulsive force acts is uncertain. Therefore, it is desirable to mainly use the suction force.
  • the transport magnetic body 201 and the positioning magnetic body 202 magnetic materials having different magnetic forces or magnetic materials having different polarities from each other are used.
  • the transport magnetic body 201 is mainly used and the positioning magnetic body 202 is used as an auxiliary, the transport efficiency is improved. Therefore, the magnetic force of the transport magnetic body 201 is made larger than that of the positioning magnetic body 202. It is desirable to keep it.
  • As a method of increasing the magnetic force of the transporting magnetic body 201 it is conceivable to increase the shape of the transporting magnetic body 201 or to use a magnetic material having a high magnetic flux density as the transporting magnetic body 201.
  • FIG. 4 is a schematic view showing the sample transport device of the second embodiment.
  • a plurality of transport magnetic materials 201 are provided.
  • the two transporting magnetic bodies 201 are provided at positions symmetrical with respect to the positioning magnetic body 202, that is, at positions opposite to each other with the positioning magnetic body 202 in between.
  • FIG. 5 is a schematic view showing the sample transport device of Example 3.
  • a plurality of transport magnetic bodies 201 are provided, but the number of transport magnetic bodies 201 is four. According to this embodiment, it is possible to further stabilize the rotational operation of the sample holder 103.
  • the present invention is not limited to the above-mentioned examples, and includes various modifications.
  • the above-described embodiment has been described in detail in order to explain the present invention in an easy-to-understand manner, and is not necessarily limited to the one including all the configurations described. It is also possible to replace a part of the configuration of one embodiment with the configuration of another embodiment, and it is also possible to add the configuration of another embodiment to the configuration of one embodiment. It is also possible to add / delete / replace a part of the configuration of each embodiment with another configuration.
  • the transport magnetic body 201 and the positioning magnetic body 202 those having a circular horizontal cross section are used, but these may be rod-shaped or a combination of a circular shape and a rod shape. It may be. Further, the circular shape is not limited to a strict circular shape, and may be an ellipse or other shape.

Abstract

La présente invention vise à fournir un dispositif de transport d'échantillon qui est apte à lire un identifiant d'un échantillon, et avec lequel une augmentation de la taille du dispositif et une réduction de la capacité de traitement peuvent être inhibées. À cet effet, la présente invention concerne un dispositif de transport d'échantillon comprenant un porte-échantillon qui comporte un corps magnétique de transport et maintient un récipient d'échantillon auquel un identifiant pour un échantillon est fixé, et une pluralité d'électroaimants qui sont disposés au-dessous d'une surface de transport et transportent le porte-échantillon en attirant ou repoussant le corps magnétique de transport, le centre de flux magnétique du corps magnétique de transport étant excentrique par rapport à l'axe central du récipient d'échantillon.
PCT/JP2020/012858 2019-07-22 2020-03-24 Dispositif de transport d'échantillon WO2021014688A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CN202080052018.XA CN114126995B (zh) 2019-07-22 2020-03-24 检测体输送装置
EP20843376.3A EP4005954A4 (fr) 2019-07-22 2020-03-24 Dispositif de transport d'échantillon
JP2021534536A JP7314278B2 (ja) 2019-07-22 2020-03-24 検体搬送装置
US17/628,650 US20220276276A1 (en) 2019-07-22 2020-03-24 Specimen conveyance device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019134328 2019-07-22
JP2019-134328 2019-07-22

Publications (1)

Publication Number Publication Date
WO2021014688A1 true WO2021014688A1 (fr) 2021-01-28

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2020/012858 WO2021014688A1 (fr) 2019-07-22 2020-03-24 Dispositif de transport d'échantillon

Country Status (5)

Country Link
US (1) US20220276276A1 (fr)
EP (1) EP4005954A4 (fr)
JP (1) JP7314278B2 (fr)
CN (1) CN114126995B (fr)
WO (1) WO2021014688A1 (fr)

Families Citing this family (1)

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Publication number Priority date Publication date Assignee Title
GB2615525A (en) * 2022-02-04 2023-08-16 Automata Tech Limited A workbench system

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JPS6169604A (ja) * 1984-09-10 1986-04-10 Mitsubishi Chem Ind Ltd 搬送装置
JP2001054459A (ja) * 1999-08-18 2001-02-27 Miyasaka Kagu Kogei Kk 飲食物容器の搬送方法及びその搬送装置
JP2003020110A (ja) * 2001-07-10 2003-01-21 Ishino Seisakusho:Kk 循環型飲食物搬送装置
JP2015502525A (ja) * 2011-11-04 2015-01-22 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 研究室試料配送システムおよび対応する動作方法
JP2018096981A (ja) 2016-12-01 2018-06-21 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ラボラトリ試料分配システムおよびラボラトリオートメーションシステム

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JPH1159901A (ja) * 1997-08-11 1999-03-02 Murata Mach Ltd キャリヤー移動装置
FR3012437B1 (fr) * 2013-10-25 2015-10-23 Biomerieux Sa Dispositif, systeme et procede de convoyage d'un objet
EP3070479B1 (fr) * 2015-03-16 2019-07-03 Roche Diagniostics GmbH Support de transport, système de distribution de marchandises de laboratoire et système d'automatisation de laboratoire
CN107407690B (zh) * 2015-03-30 2020-12-01 株式会社日立高新技术 检体搬运装置及检体搬运方法
EP3153867B1 (fr) * 2015-10-06 2018-11-14 Roche Diagniostics GmbH Système d'automatisation de laboratoire, procédé associé et système de distribution d'échantillons de laboratoire
EP3156353B1 (fr) * 2015-10-14 2019-04-03 Roche Diagniostics GmbH Support de rotation d'un support de récipient d'échantillon, système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire
WO2018024885A1 (fr) * 2016-08-04 2018-02-08 EXCEPT de AND usROCHE DIAGNOSTICS GMBH Système de distribution d'échantillons de laboratoire et système d'automatisation de laboratoire

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Publication number Priority date Publication date Assignee Title
JPS6169604A (ja) * 1984-09-10 1986-04-10 Mitsubishi Chem Ind Ltd 搬送装置
JP2001054459A (ja) * 1999-08-18 2001-02-27 Miyasaka Kagu Kogei Kk 飲食物容器の搬送方法及びその搬送装置
JP2003020110A (ja) * 2001-07-10 2003-01-21 Ishino Seisakusho:Kk 循環型飲食物搬送装置
JP2015502525A (ja) * 2011-11-04 2015-01-22 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 研究室試料配送システムおよび対応する動作方法
JP2018096981A (ja) 2016-12-01 2018-06-21 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ ラボラトリ試料分配システムおよびラボラトリオートメーションシステム

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Title
See also references of EP4005954A4

Also Published As

Publication number Publication date
EP4005954A4 (fr) 2023-07-19
US20220276276A1 (en) 2022-09-01
EP4005954A1 (fr) 2022-06-01
CN114126995B (zh) 2024-04-09
JPWO2021014688A1 (fr) 2021-01-28
CN114126995A (zh) 2022-03-01
JP7314278B2 (ja) 2023-07-25

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