WO2020238602A1 - 采集件以及采集装置 - Google Patents

采集件以及采集装置 Download PDF

Info

Publication number
WO2020238602A1
WO2020238602A1 PCT/CN2020/089674 CN2020089674W WO2020238602A1 WO 2020238602 A1 WO2020238602 A1 WO 2020238602A1 CN 2020089674 W CN2020089674 W CN 2020089674W WO 2020238602 A1 WO2020238602 A1 WO 2020238602A1
Authority
WO
WIPO (PCT)
Prior art keywords
collection
valve body
blocking
collecting
hole
Prior art date
Application number
PCT/CN2020/089674
Other languages
English (en)
French (fr)
Inventor
李剑
李亚青
李明锐
吴汉玲
蔡云
Original Assignee
深圳微伴生物有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳微伴生物有限公司 filed Critical 深圳微伴生物有限公司
Publication of WO2020238602A1 publication Critical patent/WO2020238602A1/zh

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N2001/1006—Dispersed solids
    • G01N2001/1012—Suspensions
    • G01N2001/1025—Liquid suspensions; Slurries; Mud; Sludge

Definitions

  • This application relates to the technical field of medical devices, and specifically to a collection piece and a collection device.
  • stool detection is a routine clinical laboratory test item. In the stool detection process, it is necessary to use a collection spoon or a collection stick to sample the stool.
  • the Bristol stool classification is a medical classification of stool. According to its shape, stool is divided into 7 categories, namely: Type 1: hard balls (difficult to pass); Type 2: sausage-shaped , But the surface is uneven; Type 3: Sausage-like, but with cracks on the surface; Type 4: Like a sausage or snake, and the surface is very smooth; Type 5: Soft block with smooth edges (easy to pass); Sixth Type: thick fluffy lumps, mushy stool; Type 7: watery, without solid lumps (completely liquid).
  • the structure of the collecting piece is relatively simple, and the stool sample is usually collected by rotating.
  • the existing collection pieces are only suitable for solid stool (the first type in the Bristol stool classification) To the fifth type of stool) collection, for the liquid stool (the sixth and seventh types of stool in the Bristol stool classification, especially the seventh type of stool), it is not easy to collect, which affects the collection efficiency, and the collection time is too long. Affect sample quality. Therefore, the existing collection pieces cannot meet the needs of different types of feces collection.
  • This application provides a collection piece and a collection device to solve the problem that the collection piece in the prior art cannot meet the collection needs.
  • a collection piece includes: a body having a holding end and a collection end that are arranged oppositely, and the collection end is provided with a collection hole; Used to collect solid samples; the suction and discharge part, the suction and discharge part is arranged at the other end opposite to the collection end of the body, and is connected with the collection hole, and the suction and discharge part sucks or discharges the liquid sample through the collection hole.
  • the body has a tubular structure, and the tubular structure penetrates the solid collecting part.
  • the solid collection part includes a plurality of convex walls, the plurality of convex walls are arranged at intervals along the circumferential direction of the collection end, and a sample collection area is formed between two adjacent convex walls.
  • a through hole is provided on the surface of at least one convex wall, and the through hole communicates with the sample collection area.
  • the convex wall has a free end and a connecting end that are arranged oppositely, the connecting end of the convex wall is connected to the side wall of the collecting end, and the thickness of the free end is smaller than the thickness of the connecting end.
  • the convex wall is bent in a direction away from the body, and the bending direction of each convex wall is the same.
  • the solid collection part includes: a collection shell sleeved on the collection end, the collection shell has a collection cavity, and the surface of the collection shell is a porous structure.
  • the collection shell has a spherical structure.
  • a collection device includes: a collection part, the collection part being the aforementioned collection part; a mixing tube for mixing a sample with a preservation solution to form a mixed solution, and mixing One end of the tube is detachably connected with the collection piece.
  • the collection device further includes: a liquid containing tube for storing the preservation liquid or mixed liquid, the liquid containing tube and the other end of the mixing tube are detachably connected; the valve body assembly is arranged between the mixing tube and the liquid containing tube , The valve body assembly has an open state and a closed state. When the valve body assembly is in the open state, the mixing tube is in communication with the liquid containing tube; when the valve body assembly is in the closed state, the mixing tube is separated from the liquid containing tube.
  • valve body assembly includes: a first valve body, one end of the first valve body is connected to one of the mixing pipe and the liquid receiving pipe; a second valve body, one end of the second valve body is connected to the mixing pipe and the receiving pipe The other end of the liquid pipe is connected, the other end of the second valve body is connected to the other end of the first valve body, the second valve body has a communication hole, the communication hole is used to connect the mixing tube and the liquid tube; the blocking component, Set at the communicating hole, the plugging component has a plugging position for blocking the communicating hole and a conducting position for conducting the communicating hole; the filter is arranged between the plugging component and the mixing tube, or between the plugging component and the Between the liquid tube.
  • the position between the first valve body and the second valve body is adjustable, and the relative position between the first valve body and the second valve body is adjusted to drive the plugging assembly to move between the plugging position and the conducting position .
  • the plugging assembly includes: a plugging member arranged corresponding to the communicating hole, the plugging member having a plugging end and an abutting end disposed oppositely, the abutting end is set toward the first valve body, and the plugging end is set toward the communicating hole,
  • the blocking end is used to block the communicating hole;
  • the elastic piece one end of the elastic piece is connected with the second valve body, and the other end of the elastic piece is connected with the blocking piece; when the first valve body and the second valve body move towards each other, the first A valve body squeezes the elastic piece through the plugging piece to move the plugging end of the plugging piece to the blocking position; when the first valve body and the second valve body move away from each other, the elastic piece drives the plugging piece to be blocked The position moves to the on position.
  • the blocking member includes a disc body and a guide post, the guide post is arranged on the side of the disc body facing the second valve body, the elastic part is sleeved on the guide post, and the disc body is provided with a plurality of filtrate holes ,
  • the side of the disc body facing the second valve body is provided with an annular protrusion, the guide column is located in the annular protrusion, and the annular protrusion is used to block the communication hole.
  • the guide column is a prismatic structure, and the side wall surface of the prism is a curved surface.
  • first valve body and the second valve body are threadedly connected.
  • the collection device further includes a filter element, which is arranged between the blocking component and the mixing tube.
  • the collection piece includes a body, a solid collection part, and a suction and discharge piece.
  • the main body has a holding end and a collection end that are relatively arranged, and the collection end is provided with a collection hole.
  • the solid collection part is provided at the collection end, and the suction and discharge member is provided at the other end opposite to the collection end of the main body and communicates with the collection hole.
  • the solid sample can be quantitatively collected by the solid collection part, and the liquid sample can be quantitatively sucked or discharged by controlling the suction and drainage part combined with the collection hole.
  • the collection piece is suitable for both quantitative collection of solid feces and quantitative collection of liquid feces, which can improve collection efficiency and meet the needs of feces collection.
  • Figure 1 shows an exploded view of the acquisition device provided according to an embodiment of the present application
  • Figure 2 shows a cross-sectional view of a collection device according to an embodiment of the present application
  • Fig. 3 shows a schematic diagram of the structure of the collecting piece in Fig. 1;
  • Figure 4 shows a partial enlarged view of the collecting piece in Figure 1;
  • Figure 5 shows a bottom view of the collecting piece in Figure 1;
  • FIG. 6 shows another schematic diagram of the structure of the collecting piece in FIG. 1;
  • Figure 7 shows a partial enlarged view of the collecting piece in Figure 1;
  • Fig. 8 shows a schematic structural diagram of the blocking member in Fig. 1;
  • FIG. 9 shows a schematic structural diagram of the second valve body in FIG. 1;
  • Fig. 10 shows another structural schematic diagram of the second valve body in Fig. 1.
  • valve body assembly 61. First valve body; 62. Second valve body; 621. Connecting hole; 63. Blocking assembly; 631. Blocking piece; 631a, disc body; 631b, guide post; 631c, Filtrate hole; 631d, annular protrusion; 632, elastic piece;
  • the present application provides a collection piece.
  • the collection piece includes a body 10, a solid collection part 20 and a suction and discharge part 30.
  • the main body 10 has a holding end and a collection end that are arranged oppositely, and the collection end is provided with a collection hole 11.
  • the solid collection part 20 By arranging the solid collection part 20 at the collection end, the solid sample can be collected by the solid collection part 20.
  • the suction and discharge member 30 By arranging the suction and discharge member 30 at the other end opposite to the collection end of the body and communicating with the collection hole 11, the suction and discharge member 30 can be used. The liquid sample is sucked or discharged through the collection hole 11, thereby realizing simultaneous collection of solid feces and liquid feces.
  • a collection piece in a specific embodiment, as shown in FIG. 1 to FIG. 10, according to an embodiment of the present application, a collection piece is provided.
  • the collection piece includes a body 10, a solid collection part 20 and a suction and discharge part 30.
  • the main body 10 has a holding end and a collection end that are arranged oppositely, and the collection end is provided with a collection hole 11.
  • the solid collection part 20 By arranging the solid collection part 20 at the collection end, the solid sample can be collected by the solid collection part 20.
  • the suction and discharge member 30 By arranging the suction and discharge member 30 at the other end opposite to the collection end of the body and communicating with the collection hole 11, the suction and discharge member 30 can be used. The liquid sample is sucked or discharged through the collection hole 11, thereby realizing simultaneous collection of solid feces and liquid feces.
  • the aperture of the collection hole 11 is 2 mm.
  • the suction and discharge member 30 is a liquid gel soft cap, and the liquid gel soft cap is connected to the grip end of the body 10.
  • the size of the gel head can be adjusted according to the required amount of reagents. Mark or print on the scale.
  • the suction and discharge member 30 may be a syringe-like structure, a vacuum pump, etc., as long as the suction and discharge member 30 can be used to generate a negative pressure to suck or discharge the liquid sample.
  • the suction and discharge part 30 is connected to the collection hole 11.
  • the solid collection part can be used to collect solid samples.
  • the suction and discharge member sucks or discharges liquid samples through the collection hole, so it is suitable for the collection of solid feces (the first to fifth types of stool in the Bristol Stool Classification) and the liquid feces (the No. Class 6 and Class 7 stool, especially Class 7 stool) collection.
  • the collecting member may be the aforementioned integrated wet and dry collecting part, or the solid collecting part 20 and the main body 10 may be provided as independent structures that are detachable from each other.
  • solid samples are collected by the solid collection part 20, and liquid samples are sucked or discharged by using a suction and discharge member combined with a collection hole.
  • the space of the solid sample collection part 20 is set to the required size
  • the degree of negative pressure that can be generated by the suction and discharge member 30 is set to the required size
  • the suction and discharge member 30 and the collection The volume of the pipe between the holes 11 is set to the required size, which can complete the quantitative collection of solid or liquid samples.
  • the quantitative collection is not a specific point value, but an appropriate amount of sample to be obtained. The amount of samples collected will not be too much, nor too little.
  • the body 10 has a tubular structure, and the tubular structure penetrates the solid collecting part. Specifically, the collection hole 11 is provided through the body 10 to form a tubular structure.
  • the solid collection part 20 includes a plurality of convex walls 21, which are arranged at intervals along the circumferential direction of the collection end.
  • a sample collection area is formed between two adjacent convex walls 21, which can be based on actual conditions. Need to set the number of convex walls 21, such as 3, 5, 8, or 10 convex walls 21, etc., and the space of the collection area can be set to the required size according to the needs, and the solid feces During collection, stool samples can be gathered in the sample collection area, and when the solid stool fills the sample collection area of the solid collection part 20, the quantitative collection of the sample is completed.
  • the solid collecting portion 20 includes four convex walls 21, and the four convex walls 21 are evenly spaced along the circumferential direction of the collecting end. By setting the height of the solid collection part 20 and the width of the convex wall 21, quantitative collection of stool samples can be achieved.
  • a through hole 211 is provided on the surface of at least one convex wall 21, and the through hole 211 is in communication with the sample collection area.
  • the through hole 211 is designed as a rectangular small hole.
  • the through hole 211 is designed as a round hole or other hole type.
  • the through holes 211 may be provided on the spaced convex walls 21 or on all the convex walls 21. In this embodiment, two of the four convex walls 21 at intervals are provided with through holes 211, and each convex wall 21 is provided with three rectangular small holes at intervals along the length direction.
  • the convex wall 21 has a free end 212 and a connecting end 213 oppositely arranged, and the connecting end 213 of the convex wall 21 is connected with the side wall of the collecting end.
  • the thickness of the free end 212 is smaller than the thickness of the connecting end 213, on the one hand, when the collecting piece is used to collect solid feces, it is convenient to extend the solid collecting part 20 into the solid feces; on the other hand, when the collecting piece is rotated At this time, the resistance received by the convex wall 21 can be reduced, facilitating sample collection.
  • the convex wall 21 is bent in a direction away from the main body 10, and the bending direction of each convex wall 21 is the same.
  • all of the convex walls 21 may be bent in a clockwise direction, all in a counterclockwise direction, or other bending situations.
  • the convex wall 21 forms a wheel-shaped fan blade structure in a clockwise direction.
  • the opening direction, angle, number of the convex wall 21, the shape, diameter, number of holes on the convex wall 21, and the height of the convex wall 21 can be adjusted accordingly according to actual sampling requirements.
  • the present application provides another embodiment of the collecting piece.
  • the solid collecting part 20 of the collecting piece can also adopt the structure design of the collecting shell 22, and the collecting shell 22 is set At the collecting end, the collecting shell 22 has a collecting cavity, and the surface of the collecting shell 22 has a porous structure. Set the space of the collection cavity to the required size according to needs.
  • the collecting shell 22 has multiple ribs, and the multiple ribs are staggered, and there are multiple hole-shaped structures between the multiple ribs, so that the collecting shell 22 has a porous surface and a certain accommodation space inside. Structure.
  • the collection shell 22 has a spherical structure.
  • the spherical structure of the collection shell 22 does not need to adjust the direction of use of the solid collection part 20, which has the advantage of ease of use and can improve collection efficiency.
  • a collection device includes a collection member and a mixing tube 40.
  • the collection part is the collection part provided above, and the mixing tube 40 is used to mix the sample with the preservation solution to form a mixed solution.
  • one end of the mixing tube 40 is detachably connected to the collection piece.
  • the diameter of the nozzle of the mixing tube 40 is larger than the diameter of the tube body. This arrangement facilitates the collection of stool samples to penetrate into the tube to prevent the stool samples from touching the nozzle or the user's hand, thereby enhancing the user's collection experience.
  • there is a stainless steel ball with a diameter of 5-7 mm in the mixing tube 40 which is used for the homogenization operation of the sample.
  • the mixing tube 40 mainly implements the mixing and homogenization of the sample through the design of steel balls and the solid collection part 20.
  • the sample can be mixed or homogenized by designing a brush or other structure on the bottom or side wall of the mixing tube 40 to match the solid collection part 20, or the solid collection part can be
  • the connection between 20 and the main body 10 is designed as a breakable structure, and the broken solid collecting part 20 replaces the function of the steel ball. For example, creases may be provided.
  • the operator inserts the collection piece into the mixing tube 40 obliquely and applies a certain force to break the crease, and the solid collection part 20 and the collection end or part of the collection end fall into the mixing tube.
  • the solid collection part 20 is connected to the body 10 through a detachable buckle structure. After the sample collection is completed, the buckle structure is released, so that the solid collection part 20 and the collection end or part of the collection end fall into the mix Even the tube is medium.
  • the collection device further includes a liquid containing tube 50 and a valve body assembly 60.
  • the liquid containing tube 50 is used to store the preservation liquid or mixed liquid.
  • the liquid containing tube 50 and the other end of the mixing tube 40 are detachably connected, and the valve body assembly 60 is provided Between the mixing tube 40 and the liquid containing tube 50.
  • the valve body assembly 60 has an open state and a closed state. When the valve body assembly 60 is in the open state, the mixing tube 40 is in communication with the liquid containing tube 50; when the valve body assembly 60 is in the closed state, the mixing tube 40 It is separated from the liquid containing pipe 50.
  • both the bottom and sides of the liquid containing tube 50 can be provided with a printed one-dimensional code or two-dimensional code for sample information tracking and recording.
  • the one-dimensional code or the two-dimensional code can be pasted, sprayed, etc. Set at the bottom and sides of the liquid containing tube 50.
  • the valve body assembly 60 on the upper portion of the liquid containing tube 50 can be replaced with a tube cover as needed.
  • the tube cover is hexagonal in the groove, and the bottom is hexagonal or hexagonal. The structure of the cover and the tube bottom can be fixed by the corresponding opening instrument and realize automatic opening of the instrument, so as to complete subsequent sample detection.
  • the valve body assembly 60 includes a first valve body 61, a second valve body 62, a blocking assembly 63 and a filter 70.
  • One end of the first valve body 61 is connected to one of the mixing tube 40 and the liquid containing tube 50
  • one end of the second valve body 62 is connected to the other of the mixing tube 40 and the liquid containing tube 50
  • the second The other end of the valve body 62 is connected to the other end of the first valve body 61.
  • the second valve body 62 has a communication hole 621 for connecting the mixing tube 40 and the liquid receiving tube 50.
  • the blocking component 63 is disposed at the communication hole 621, and the blocking component 63 has a blocking position for blocking the communication hole 621 and a conducting position for conducting the communication hole 621.
  • the filter 70 is arranged between the plugging component 63 and the mixing tube 40 or between the plugging component 63 and the liquid receiving tube 50.
  • one end of the first valve body 61 is connected to the mixing tube 40, and one end of the second valve body 62 is connected to the liquid receiving tube 50, and the filter 70 is arranged between the blocking assembly 63 and the mixing tube 40 .
  • the position between the first valve body 61 and the second valve body 62 is adjustable, and the plugging assembly 63 is driven by adjusting the relative position between the first valve body 61 and the second valve body 62 Move between the blocked position and the on position.
  • the position between the first valve body 61 and the second valve body 62 can be adjusted by pushing and pulling, or a threaded structure can be provided between the first valve body 61 and the second valve body 62, by rotating the first valve body 61 or the second valve body 62 to adjust the relative position between the two.
  • a threaded structure is provided between the first valve body 61 and the second valve body 62.
  • the blocking component 63 includes a blocking member 631 and an elastic member 632.
  • the elastic member 632 is preferably a spring
  • the blocking member 631 is provided corresponding to the communicating hole 621
  • the blocking member 631 has a blocking end and abutting end disposed oppositely.
  • the abutting end is disposed toward the first valve body 61, and the blocking end faces
  • the communication hole 621 is provided, and the blocking end is used to block the communication hole 621.
  • one end of the spring is connected to the second valve body 62, and the other end of the spring is connected to the blocking member 631.
  • three supporting points are provided in the second valve body 62, and the spring can be supported by the three supporting points.
  • the first valve body 61 and the second valve body 62 move towards each other, the first valve body 61 presses the spring through the blocking member 631 to move the blocking end of the blocking member 631 to the blocking position;
  • the spring-driven blocking member 631 moves from the blocking position to the conducting position.
  • the blocking member 631 includes a disc body 631a and a guide column 631b, and the body 631a and the guide column 631b are integrally formed, and the blocking member 631 has a planar umbrella structure as a whole.
  • the guide post 631b is arranged on the side of the disc body 631a facing the second valve body 62, and the spring is sleeved on the guide post 631b.
  • the disc body 631a is provided with a plurality of filtrate holes 631c, and the disc body 631a spaced from the filtrate holes 631c has a tripod structure in the middle, which mainly plays a role of strengthening the circumference of the disc body 631a.
  • annular protrusion 631d is provided on the side of the disc body 631a facing the second valve body 62, the guide post 631b is located in the annular protrusion 631d, and the annular protrusion 631d is used to block the communication hole 621.
  • the diameter of the communicating hole 621 is slightly smaller than the diameter of the annular protrusion 631d.
  • the annular protrusion 631d can completely block the communicating hole 621 to achieve a sealing effect.
  • the guide post 631b has a prismatic structure, and the sidewall surface of the prism is a curved surface.
  • the guide post 631b is a three-pronged columnar structure, and the cavity formed between the two branches of the three-pronged structure can facilitate the drainage of liquid from the filtrate hole 631c into the liquid containing tube 50.
  • first valve body 61 and the second valve body 62 are threadedly connected. By rotating the first valve body 61 or the second valve body 62, the gap between the first valve body 61 or the second valve body 62 can be adjusted. To drive the plugging assembly 63 to move between the plugging position and the conducting position.
  • the thread directions of the first valve body 61 and the second valve body 62 are positive threads, and the thread directions of the second valve body 62 and the liquid receiving pipe 50 are reverse threads, so as to avoid misoperation when opening the filter. Liquid pipe.
  • the nozzle and bottom of the mixing tube 40 are both threaded structures, so that the threaded connection between the collecting part and the mixing tube 40 can be realized, and the mixing tube 40 and the first valve body 61 are threadedly connected.
  • the collection part includes a liquid gel soft cap, a solid collection part 20 and a mixing tube cover.
  • the solid collection part 20 is connected with the mixing tube cover, and the mixing tube cover is threadedly connected with the mixing tube 40 to realize the collection part and mixing. Connection of tube 40.
  • the second valve body 62 and the liquid receiving tube 50 are screwed.
  • the direction of rotation of the threads of the mixing tube 40 and the first valve body 61 is opposite to that of the second valve body 62 and the liquid receiving tube 50, which prevents the user from screwing the mixing tube 40 and the liquid receiving tube 50 at the same time during operation.
  • the collection device further includes a filter 70 which is arranged between the blocking assembly 63 and the mixing tube 40.
  • the filter element 70 is a filter mesh with small holes with a diameter of 1 mm on the upper part of the filter mesh, which are mainly used to filter large particle residues in feces, and the pore size and number of layers of the filter mesh can be adjusted according to actual needs.
  • the preservation effect of the sample in the protective solution can be improved to a certain extent, on the other hand, it can prevent the large particles from clogging the pipette tip during subsequent testing and sampling. Affect the sampling of pipettes or pipetting instruments.
  • valve body assembly 60 there is a sealing ring between the valve body assembly 60 and the filter element 70, which is mainly used to improve the sealing performance of the collection device and avoid liquid overflow.
  • the collection piece, the mixing tube 40, and the liquid containing tube 50 are connected in sequence.
  • the assembly sequence and structural position of the components can be combined according to actual use needs, manufacturing processes, manufacturing costs, etc. ,Adjustment.
  • valve body assembly 60 Before use, the valve body assembly 60 is in a closed state, and a certain volume of sample protection liquid is contained in the liquid receiving tube 50.
  • valve body assembly 60 According to the prompt on the outside of the valve body assembly 60, rotate the first valve body 61 to move the blocking assembly 63 to the blocking position, so that the valve body assembly 60 is in a closed state.
  • the sample After homogenization, the sample enters the liquid containing tube 50 through the filter screen and the blocking member 631 to complete the filtration of large particle impurities and fibers of the sample. During this period, the gel head can be squeezed to accelerate the filtration of the sample.
  • the liquid receiving tube 50 may be a soft rubber tube, and the liquid filtering can be accelerated by squeezing the liquid receiving tube 50.
  • valve body assembly 60 can be modified into a specific pipe cover according to the needs of transportation, storage or testing.
  • the operations after step 7) can be performed by the user of the sampling, or can be sent to the sample testing center for completion.
  • the collection piece can collect solid feces or liquid feces separately, and can also collect solid feces and liquid feces at the same time, which can meet the needs of feces collection.
  • the collection piece can realize quantitative collection of an appropriate amount of samples.
  • the wide-mouth design of the mixing tube 40 greatly facilitates the timely, safe, and hygienic insertion of the collection pieces with samples into the mixing tube 40, which prevents users from worrying about the feces touching the tube opening or getting on their hands.
  • the collection device can realize the homogenization operation of the sample, and can realize the filtration of large particle residues in the stool sample.
  • the collection device simultaneously realizes the requirements of quantitative collection, sample homogenization, residue filtration, and preservation of liquid to avoid spilling.
  • the user can obtain a better sampling experience during the entire sampling process, such as as few sampling operations as possible, and no need to worry about spilling and contacting the preservation liquid.
  • the above-mentioned processed samples can meet the high-throughput and high-efficiency requirements of testing centers/hospitals for sample processing and testing samples.
  • orientation words such as “front, back, up, down, left, right", “horizontal, vertical, vertical, horizontal” and “top, bottom”, etc. indicate the orientation Or positional relationship is usually based on the positional or positional relationship shown in the drawings, which is only used to facilitate the description of the present invention and simplify the description. Unless otherwise stated, these positional words do not indicate or imply the pointed device or element It must have a specific orientation or be constructed and operated in a specific orientation, so it cannot be understood as a limitation of the protection scope of the present invention; the orientation word “inside and outside” refers to the inside and outside relative to the contour of each component itself.
  • spatially relative terms such as “above”, “above”, “above”, “above”, etc. can be used here to describe as shown in the figure. Shows the spatial positional relationship between one device or feature and other devices or features. It should be understood that the spatially relative terms are intended to encompass different orientations in use or operation other than the orientation of the device described in the figure. For example, if the device in the figure is inverted, then the device described as “above the other device or structure” or “above the other device or structure” will then be positioned as “below the other device or structure” or “on Under other devices or structures”. Thus, the exemplary term “above” can include both orientations “above” and “below”. The device can also be positioned in other different ways (rotated by 90 degrees or in other orientations), and the relative description of the space used here is explained accordingly.
  • the collection piece includes a body, a solid collection part, and a suction and discharge piece.
  • the main body has a holding end and a collection end that are relatively arranged, and the collection end is provided with a collection hole.
  • the solid collection part is provided at the collection end, and the suction and discharge member is provided at the other end opposite to the collection end of the main body and communicates with the collection hole.
  • the solid sample can be quantitatively collected by the solid collection part, and the liquid sample can be quantitatively sucked or discharged by controlling the suction and drainage part combined with the collection hole.
  • the collection piece is suitable for both quantitative collection of solid feces and quantitative collection of liquid feces, which can improve collection efficiency and meet the needs of feces collection.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hydrology & Water Resources (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

一种采集件以及采集装置，能够解决现有技术中的采集件无法满足采集需要的问题。采集件包括：本体（10），具有相对设置的握持端和采集端，采集端设置有采集孔（11）；固体采集部（20），设置在采集端，固体采集部（20）用于采集固体样本；吸排件（30），吸排件（30）设于与本体（10）的采集端相对的另一端，并与采集孔（11）连通，吸排件（30）通过采集孔（11）吸取或排放液体样本。

Description

采集件以及采集装置
本申请要求于2019年5月30日提交至中国国家知识产权局、申请号为201910464782.7、发明名称为“采集件以及采集装置”的专利申请的优先权。
技术领域
本申请涉及医疗器械技术领域，具体而言，涉及一种采集件以及采集装置。
背景技术
目前，粪便检测为临床常规化验项目，在粪便检测过程中，需要借助采集勺或采集棒对粪便进行取样。
布里斯托大便分类法是一种医学上对粪便的分类法，根据形态将大便分为7大类，分别为：第一型：一颗颗硬球(很难通过)；第二型：香肠状，但表面凹凸；第三型：香肠状，但表面有裂痕；第四型：像香肠或蛇一样，且表面很光滑；第五型：断边光滑的柔软块状(容易通过)；第六型：粗边蓬松块，糊状大便；第七型：水状，无固体块(完全液体)。
现有技术中，采集件的结构较为简单，通常是通过旋转的方式对粪便样本进行采集。而在取样过程中，由于粪便有固态和液态(如上述的布里斯托大便分类法的7类大便)，因此现有的采集件仅适合固态粪便(布里斯托大便分类法中的第一类至第五类大便)采集，对于液态粪便(布里斯托大便分类法中的第六类和第七类大便，特别是第七类大便)则不易采集，影响采集效率，且采集时间过长会影响样本质量。因此现有的采集件无法满足不同类型的粪便采集需要。
发明内容
本申请提供一种采集件以及采集装置，以解决现有技术中的采集件无法满足采集需要的问题。
根据本申请的一个方面，提供了一种采集件，采集件包括：本体，具有相对设置的握持端和采集端，采集端设置有采集孔；固体采集部，设置在采集端，固体采集部用于采集固体样本；吸排件，吸排件设于与本体的采集端相对的另一端，并与采集孔连通，吸排件通过采集孔吸取或排放液体样本。
进一步地，本体为管状结构，管状结构贯穿固体采集部。
进一步地，固体采集部包括：多个凸壁，多个凸壁沿采集端的圆周方向间隔设置，相邻两个凸壁之间形成样本采集区。
进一步地，至少一个凸壁的表面上设置有通孔，通孔与样本采集区连通。
进一步地，凸壁具有相对设置的自由端和连接端，凸壁的连接端与采集端的侧壁连接，自由端的厚度小于连接端的厚度。
进一步地，凸壁沿远离本体的方向弯曲，且每个凸壁的弯曲方向相同。
进一步地，固体采集部包括：采集壳，套设在采集端，采集壳内具有采集腔，采集壳的表面为多孔结构。
进一步地，采集壳为球形结构。
根据本申请的另一方面，提供了一种采集装置，采集装置包括：采集件，采集件为上述提供的采集件；混匀管，用于将样本与保存液混合以形成混合液，混匀管的一端与采集件可拆卸连接。
进一步地，采集装置还包括：盛液管，用于存储保存液或混合液，盛液管与混匀管的另一端可拆卸连接；阀体组件，设置在混匀管和盛液管之间，阀体组件具有打开状态和封闭状态，当阀体组件处于打开状态时，混匀管与盛液管导通；当阀体组件处于封闭状态时，混匀管与盛液管隔断。
进一步地，阀体组件包括：第一阀体，第一阀体的一端与混匀管和盛液管中的其中一个连接；第二阀体，第二阀体的一端与混匀管和盛液管中的另一个连接，第二阀体的另一端与第一阀体的另一端连接，第二阀体具有连通孔，连通孔用于连通混匀管和盛液管；封堵组件，设置在连通孔处，封堵组件具有封堵连通孔的封堵位置以及导通连通孔的导通位置；过滤件，设置在封堵组件与混匀管之间，或设置在封堵组件与盛液管之间。
进一步地，第一阀体和第二阀体之间位置可调，通过调节第一阀体和第二阀体之间的相对位置以驱动封堵组件在封堵位置和导通位置之间移动。
进一步地，封堵组件包括：封堵件，对应连通孔设置，封堵件具有相对设置的封堵端和抵接端，抵接端朝向第一阀体设置，封堵端朝向连通孔设置，封堵端用于封堵连通孔；弹性件，弹性件的一端与第二阀体连接，弹性件的另一端与封堵件连接；当第一阀体和第二阀体相向移动时，第一阀体通过封堵件挤压弹性件，以使封堵件的封堵端移动至封堵位置；当第一阀体和第二阀体相互远离时，弹性件驱动封堵件由封堵位置移动至导通位置。
进一步地，封堵件包括圆盘本体和导向柱，导向柱设置在圆盘本体的朝向第二阀体的一侧，弹性件套设在导向柱上，圆盘本体上设置有多个滤液孔，圆盘本体的朝向第二阀体的一侧设置有环形凸起，导向柱位于环形凸起内，环形凸起用于封堵连通孔。
进一步地，导向柱为棱柱结构，棱柱的侧壁表面为曲面。
进一步地，第一阀体和第二阀体为螺纹连接。
进一步地，采集装置还包括：过滤件，设置在封堵组件与混匀管之间。
应用本申请的技术方案，该采集件包括本体、固体采集部以及吸排件。其中，本体具有相对设置的握持端和采集端，采集端设置有采集孔。具体的，固体采集部设置在采集端，吸排件设于与本体的采集端相对的另一端，并与采集孔连通。当需要对粪便进行取样时，利用固体采集部能够定量采集固体样本，通过控制吸排件结合采集孔能够定量吸取或排放液体样本。采用上述结构，该采集件既适合定量采集固态粪便又适合定量采集液态粪便，从而能够提高采集效率，进而满足粪便采集需要。
附图说明
构成本申请的一部分的说明书附图用来提供对本申请的进一步理解，本申请的示意性实施例及其说明用于解释本申请，并不构成对本申请的不当限定。在附图中：
图1示出了根据本申请实施例提供的采集装置的爆炸图；
图2示出了根据本申请实施例提供的采集装置的剖视图；
图3示出了图1中的采集件的结构示意图；
图4示出了图1中的采集件的局部放大图；
图5示出了图1中的采集件的仰视图；
图6示出了图1中的采集件的又一结构示意图；
图7示出了图1中的采集件的局部放大图；
图8示出了图1中的封堵件的结构示意图；
图9示出了图1中的第二阀体的结构示意图；
图10示出了图1中的第二阀体的又一结构示意图。
其中，上述附图包括以下附图标记：
10、本体；11、采集孔；
20、固体采集部；21、凸壁；211、通孔；212、自由端；213、连接端；22、采集壳；
30、吸排件；
40、混匀管；
50、盛液管；
60、阀体组件；61、第一阀体；62、第二阀体；621、连通孔；63、封堵组件；631、封堵件；631a、圆盘本体；631b、导向柱；631c、滤液孔；631d、环形凸起；632、弹性件；
70、过滤件。
具体实施方式
下面将结合本申请实施例中的附图，对本申请实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本申请一部分实施例，而不是全部的实施例。以下对至少一个示例性实施例的描述实际上仅仅是说明性的，决不作为对本申请及其应用或使用的任何限制。基于本申请中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本申请保护的范围。
如图2、图3、图4所示，本申请提供一种采集件，采集件包括本体10、固体采集部20以及吸排件30。其中，本体10具有相对设置的握持端和采集端，且采集端设置有采集孔11。通过将固体采集部20设置在采集端，可以利用固体采集部20采集固体样本，通过将吸排件30设于与本体的采集端相对的另一端，并与采集孔11连通，可以利用吸排件30通过采集孔11吸取或排放液体样本，从而能够实现对固体粪便和液态粪便的同时采集。
在一个具体实施例中，如图1至图10所示，根据本申请的实施例提供了一种采集件，采集件包括本体10、固体采集部20以及吸排件30。其中，本体10具有相对设置的握持端和采集端，且采集端设置有采集孔11。通过将固体采集部20设置在采集端，可以利用固体采集部20采集固体样本，通过将吸排件30设于与本体的采集端相对的另一端，并与采集孔11连通，可以利用吸排件30通过采集孔11吸取或排放液体样本，从而能够实现对固体粪便和液态粪便的同时采集。具体的，采集孔11的孔径为2mm。在本实施例中，吸排件30为液体凝胶软帽，且液体凝胶软帽与本体10的握持端连接，凝胶头的尺寸可根据试剂需求量进行调整，可视需求在采集件上进行刻度标记或者打印。当采集液态粪便时，通过挤压液体凝胶软帽，样本即可在压差的作用下进入采集孔11，以实现水状样本的定量采集。在其它实施例中，吸排件30可以为类似注射器的结构、真空泵等，只要能够利用吸排件30产生负压作用吸取或排放液体样本即可。应用本实施例提供的采集件，通过在本体10的采集端设置固体采集部20，将吸排件30与采集孔11连通，当需要对粪便进行取样时，能够利用固体采集部采集固体样本，利用吸排件通过采集孔吸取或排放液体样本，从而既适合固态粪便(布里斯托大便分类法中的第一类至第五类大便)的采集又适合液态粪便(布里斯托大便分类法中的第六类和第七类大便，特别是第七类大便)的采集。如此设置，可以根据需要单独对固体粪便或液态粪便进行采集，或同时对固体粪便和液态粪便(比如布里斯托大便分类法中的第六类大便)的进行采集，能够提高采集效率，满足粪便采集需要。并且，采集件可以为上述的干湿两用一体化的采集部，也可将固体采集部20和本体10设置为相互可拆卸的独立结构。
需要说明的是，本申请通过固体采集部20采集固体样本，通过利用利用吸排件结合采集孔吸取或排放液体样本。其中，根据具体的情况，将固体采集部20容纳固体样本的空间设定为所需要的大小，将吸排件30的能够产生的负压程度设定为所需要的大小或者将吸排件30与采集孔11之间的管道的体积设定为所需要的大小，可完成对固体或液态样本的定量采集，所述定量采集并不是一个特定的点值，而是为能够恰当获得样本的量，使得采集的样本的量不会太多，也不会太少。
在本实施例中，本体10为管状结构，且管状结构贯穿固体采集部。具体的，采集孔11贯穿本体10设置，从而形成管状结构。
如图3至图5所示，固体采集部20包括多个凸壁21，多个凸壁21沿采集端的圆周方向间隔设置，相邻两个凸壁21之间形成样本采集区，可根据实际的需要设置凸壁21的数量，比如由3个、5个、8个或10个等凸壁21构成，并可根据需要将采集区的空间设为所需的大小，利用采集件对固体粪便进行采集时，粪便样本可以聚集在样本采集区，当固体粪便填充满固体采集部20的样本采集区后，即完成了样本的定量采集。在本实施例中，固体采集部20包括四个凸壁21，且四个凸壁21沿采集端的圆周方向间隔均匀设置。通过设置固体采集部20的高度和凸壁21的宽度，可实现对粪便样本进行定量采集。
为了便于对粪便样本与保存液混合，至少一个凸壁21的表面上设置有通孔211，且通孔211与样本采集区连通。通过在凸壁21的表面上设置有通孔211，当需要将粪便样本与保存液混合时，保存液能够通过对通孔211对凸壁21进行冲刷，避免粪便样本粘结到凸壁21上难以掉落，通过该结构能够便于粪便样本与保存液的匀浆化操作。具体的，由于采集件尺寸较小，凸壁21的结构较窄，为了尽可能增大孔径，让液体和样本通过孔径，而考虑将通孔211设计为矩形小孔，也可以根据具体使用情况将通孔211设计为圆孔或其他孔型。通孔211可设置在间隔的凸壁21上，也可设置在所有的凸壁21上。在本实施例中，四个凸壁21中的间隔设置的两个凸壁21上设置有通孔211，且每个凸壁21沿长度方向间隔设置有三个矩形小孔。
其中，凸壁21具有相对设置的自由端212和连接端213，凸壁21的连接端213与采集端的侧壁连接。通过将自由端212的厚度设置为小于连接端213的厚度，一方面，当利用采集件对固体粪便进行采集时，便于将固体采集部20伸入固体粪便中；另一方面，当旋转采集件时，能够减小凸壁21受到的阻力，便于对样本进行采集。
具体的，凸壁21沿远离本体10的方向弯曲，且每个凸壁21的弯曲方向相同，比如，可都顺时针方向弯曲、都逆时针方向弯曲或其他弯曲的情况。在本实施例中，凸壁21沿顺时针方向形成轮状扇叶结构。其中，凸壁21的开口方向、角度、数量、凸壁21上孔的形状、孔径、数量、凸壁21的高度等均可根据实际采样需求进行相应的调整。
如图6和图7所示，本申请提供了采集件的又一实施例，在该实施例中，采集件的固体采集部20还可以采用采集壳22的结构设计，将采集壳22套设在采集端，采集壳22内具有采集腔，且采集壳22的表面为多孔结构。根据需要将采集腔的空间设为所需的大小，采用上述结构，利用固体采集部20对固态粪便进行采集时，固态粪便可通过采集壳22表面的多孔结构进入采集腔内，即完成了样本的定量采集。在本实施例中，采集壳22具有多根筋条，且多根筋条交错分布，多根筋条之间具有多个孔形结构，以使采集壳22形成表面多孔和内部具有一定容纳空间的结构。
具体的，采集壳22为球形结构。当需要采集样本时，采用球形结构的采集壳22无需调整固体采集部20的使用方向，具有便于使用的优点，可以提升采集效率。
如图1和图2所示，根据本申请的又一实施例提供了一种采集装置，该采集装置包括采集件和混匀管40。其中，采集件为上述提供的采集件，混匀管40用于将样本与保存液混合以形成混合液。具体的，混匀管40的一端与采集件可拆卸连接。在本实施例中，混匀管40的管口直径大于管体直径，如此设置便于沾有粪便样本的采集件深入管内，避免粪便样本碰到管口或者用户手上，提升用户采集体验。并且，混匀管40的管内有一颗直径5-7mm的不锈钢钢珠，用于样本的匀浆化操作。
在本实施例中，混匀管40主要通过钢珠、固体采集部20的设计实现样本的混匀、匀浆化。这一步操作，也可以通过在混匀管40的管底或侧壁上设计与固体采集部20相匹配的刷装或者其他结构实现样本的混匀或者匀浆化操作，或者可将固体采集部20与本体10的连接处设计成可断落的结构，将断落的固体采集部20替代钢珠的功能。比如，可以设有折痕，样本采集完成后，操作者将采集件倾斜插入混匀管40中施加一定的力，使得折痕断裂，固体采集部20与采集端或部分采集端掉入混匀管40中；又或者将固体采集部20通过可断落的卡扣结构与本体10连接，样本采集完成后，松开卡扣结构，使得固体采集部20与采集端或部分采集端掉入混匀管中等。
其中，采集装置还包括盛液管50和阀体组件60，盛液管50用于存储保存液或混合液，盛液管50与混匀管40的另一端可拆卸连接，阀体组件60设置在混匀管40和盛液管50之间。具体的，阀体组件60具有打开状态和封闭状态，当阀体组件60处于打开状态时，混匀管40与盛液管50导通；当阀体组件60处于封闭状态时，混匀管40与盛液管50隔断。在本实施例中，盛液管50的管底和侧部均可设有打印一维码或者二维码用于样本信息追踪及记录，一维码或二维码可通过粘贴、喷绘等方式设在盛液管50的管底和侧部。
并且，将盛液管50与混匀管分离后，可根据需要将盛液管50上部的阀体组件60改换为管盖。优选的，管盖为凹槽内六角，底部呈六角形或者六角卡纹，盖子和管底的结构可被相应的开盖仪器固定并实现仪器自动化开盖，以便于完成后续样品检测。
具体的，阀体组件60包括第一阀体61、第二阀体62、封堵组件63以及过滤件70。其中，第一阀体61的一端与混匀管40和盛液管50中的其中一个连接，第二阀体62的一端与混匀管40和盛液管50中的另一个连接，第二阀体62的另一端与第一阀体61的另一端连接。并且，第二阀体62具有连通孔621，连通孔621用于连通混匀管40和盛液管50。具体的，封堵组件63设置在连通孔621处，且封堵组件63具有封堵连通孔621的封堵位置以及导通连通孔621的导通位置。其中，过滤件70设置在封堵组件63与混匀管40之间，或设置在封堵组件63与盛液管50之间。在本实施例中，第一阀体61的一端与混匀管40连接，第二阀体62的一端与盛液管50连接，过滤件70设置在封堵组件63与混匀管40之间。
如图9和图10所示，第一阀体61和第二阀体62之间位置可调，通过调节第一阀体61和第二阀体62之间的相对位置以驱动封堵组件63在封堵位置和导通位置之间移动。其中，可以通过推拉的方式调节第一阀体61和第二阀体62之间的位置，也可以在第一阀体61和第二阀体62之间设置螺纹结构，通过旋转第一阀体61或第二阀体62来调节二者之间的相对位置。在本实施例中，第一阀体61和第二阀体62之间设置有螺纹结构。
具体的，封堵组件63包括封堵件631和弹性件632。其中，弹性件632优选为弹簧，封堵件631对应连通孔621设置，封堵件631具有相对设置的封堵端和抵接端，抵接端朝向第一阀体61设置，封堵端朝向连通孔621设置，且封堵端用于封堵连通孔621。具体的，弹簧的一端与第二阀体62连接，弹簧的另一端与封堵件631连接。具体的，第二阀体62内设置有三个支撑点，可利用三个支撑点托住弹簧。当第一阀体61和第二阀体62相向移动时，第一阀体61通过封堵件631挤压弹簧，以使封堵件631的封堵端移动至封堵位置；当第一阀体61和第二阀体62相互远离时，弹簧驱动封堵件631由封堵位置移动至导通位置。
如图8所示，封堵件631包括圆盘本体631a和导向柱631b，且本体631a和导向柱631b为一体成型结构，封堵件631整体呈平面伞状结构。具体的，导向柱631b设置在圆盘本体631a的朝向第二阀体62的一侧，弹簧套设在导向柱631b上。其中，圆盘本体631a上设置有多个滤液孔631c，与滤液孔631c相间隔的圆盘本体631a中间有三角架结构，主要起到圆盘本体631a周圈加固作用。并且，圆盘本体631a的朝向第二阀体62的一侧设置有环形凸起631d，导向柱631b位于环形凸起631d内，环形凸起631d用于封堵连通孔621。
其中，连通孔621的直径略小于环形凸起631d的直径，当环形凸起631d与连通孔621相接触时，环形凸起631d可完全封堵连通孔621以达到密闭效果。具体的，导向柱631b为棱柱结构，且棱柱的侧壁表面为曲面。在本实施例中，导向柱631b为三叉柱状结构，三叉结构的两两分叉之间形成的容腔可便于将液体由滤液孔631c引流至盛液管50内。
在本实施例中，第一阀体61和第二阀体62为螺纹连接，通过旋转第一阀体61或第二阀体62，可以调节第一阀体61或第二阀体62之间的相对位置，以驱动封堵组件63在封堵位置和导通位置之间移动。并且，第一阀体61和第二阀体62的螺纹方向呈正向螺纹，第二阀体62与盛液管50相连的螺纹方向呈反向螺纹，避免用于在打开过滤时误操作打开盛液管。
具体的，混匀管40的管口和底部均为螺纹结构，如此可实现采集件与混匀管40的螺纹连接，且混匀管40与第一阀体61为螺纹连接。其中，采集件包括液体凝胶软帽、固体采集部20以及混匀管盖，固体采集部20与混匀管盖连接，混匀管盖与混匀管40螺纹连接以实现采集件与混匀管40的连接。并且，第二阀体62与盛液管50为螺纹连接。其中，混匀管40与第一阀体61的螺纹旋转方向与第二阀体62与盛液管50的螺纹相反，避免用户在操作时同时拧动混匀管40和盛液管50。
为了对样本中的杂质进行过滤，采集装置还包括过滤件70，过滤件70设置在封堵组件63与混匀管40之间。在本实施例中，过滤件70为过滤网，过滤网上部有直径1mm的小孔，主要用于过滤粪便中的大颗粒残渣，且过滤网的孔径、层数均可以根据实际需求进行调整。其中，样本经过该结构过滤掉大颗粒的残渣后，一方面一定程度上可提高样本在保护液中的保存效果，另一方面，可避免在后续检测取样时，大颗粒物堵塞移液枪头，影响移液枪或者移液仪器的取样。
在本实施例中，阀体组件60与过滤件70之间有密封圈，主要用于提高采集装置的密封性，避免液体溢出。
在本实施例中，采集件、混匀管40以及盛液管50顺次连接，在其它实施例中，部件的组装顺序、结构位置均可以根据实际使用需要、制作工艺、制作成本等进行组合、调整。
为了便于理解本实施例提供的装置，下面结合采集过程进行说明：
1)使用前，阀体组件60呈封闭状态，盛液管50内装有一定体积的样本保护液。
2)采集样本时，旋转打开混匀管旋盖，手持管盖部取出本体10。
3)采样：若粪便样本状态为固体粪便，则将固体采集部20垂直伸入粪便样本，顺时针旋转1-3圈。为了提高样本的多样性，可根据情况在2-3个位置取样，根据需求在每个位置顺时针旋转1-2圈。若采集液态粪便，则挤压本体10上面的凝胶头进行采集足量样本，样本由采集孔11进入采集件中。采集后，将混匀管旋盖与混匀管40拧紧。
4)根据阀体组件60外侧的提示，旋转第一阀体61使封堵组件63移动至导通位置，以使阀体组件60处于打开状态。
5)将采集装置倒置，盛液管50中的保存液通过连通孔621及滤网进入混匀管40内。
6)根据阀体组件60外侧的提示，旋转第一阀体61使封堵组件63移动至封堵位置，以使阀体组件60处于封闭状态。
7)将采集管直立，如果是固体粪便样本，通过颠倒混匀钢珠数十次，将样本分散至保护液中实现匀浆化；若是液态粪便样本，则通过挤压凝胶头将样本分散混匀至保护液中。
8)样本充分匀浆化后，根据阀体组件60外侧的提示，旋转第一阀体61使封堵组件63移动至导通位置，以使阀体组件60处于打开状态。
9)匀浆化后样本通过滤网、封堵件631进入盛液管50，完成样本的大颗粒杂质、纤维等过滤。在此期间可通过挤压凝胶头，加速样本的过滤。并且，盛液管50可为软胶管，通过挤压盛液管50可加速液体过滤。
10)根据阀体组件60外侧的提示，旋转第一阀体61使封堵组件63移动至封堵位置，以使阀体组件60处于封闭状态。
11)阀体组件60可根据运输、保存或者检测需要更化成特定的管盖。
其中，步骤7)之后的操作，既可以由采样的用户操作，也可以之后寄送至样本检测中心完成。
通过本实施例提供的装置，具有以下有益效果：
(1)该采集件既可以分别对固体粪便或液态粪便进行采集，又可以同时对固体粪便和液态粪便的进行采集，能够满足粪便采集需要。
(2)该采集件可实现适量样本的定量采集。
(3)混匀管40的广口设计，极大便利了沾有样本的采集件及时、安全、卫生的放入混匀管40，避免了用户担心粪便碰到管口或者沾到手上。
(4)该采集装置可实现样本的匀浆化操作，可实现粪便样本中的大颗粒残渣过滤。
(5)该采集装置同时实现了定量采集、样本匀浆化、残渣过滤、保存液避免洒出的需求。
(6)通过上述方式，用户在整个采样过程中可获得较好的采样体验，如尽量少的采样操作、不需担心保存液洒出并接触。
(7)经过上述处理的样本可满足检测中心/医院等对于样本处理、检测样本的高通量、高效率的需求。
需要注意的是，这里所使用的术语仅是为了描述具体实施方式，而非意图限制根据本申请的示例性实施方式。如在这里所使用的，除非上下文另外明确指出，否则单数形式也意图包括复数形式，此外，还应当理解的是，当在本说明书中使用术语“包含”和/或“包括”时，其指明存在特征、步骤、操作、器件、组件和/或它们的组合。
除非另外具体说明，否则在这些实施例中阐述的部件和步骤的相对布置、数字表达式和数值不限制本发明的范围。同时，应当明白，为了便于描述，附图中所示出的各个部分的尺寸并不是按照实际的比例关系绘制的。对于相关领域普通技术人员已知的技术、方法和设备可能不作详细讨论，但在适当情况下，所述技术、方法和设备应当被视为授权说明书的一部分。在这里示出和讨论的所有示例中，任何具体值应被解释为仅仅是示例性的，而不是作为限制。因此，示例性实施例的其它示例可以具有不同的值。应注意到：相似的标号和字母在下面的附图中表示类似项，因此，一旦某一项在一个附图中被定义，则在随后的附图中不需要对其进行进一步讨论。
在本发明的描述中，需要理解的是，方位词如“前、后、上、下、左、右”、“横向、竖向、垂直、水平”和“顶、底”等所指示的方位或位置关系通常是基于附图所示的方位或位置关系，仅是为了便于描述本发明和简化描述，在未作相反说明的情况下，这些方位词并不指示和暗示所指的装置或元件必须具有特定的方位或者以特定的方位构造和操作，因此不能理解为对本发明保护范围的限制；方位词“内、外”是指相对于各部件本身的轮廓的内外。
为了便于描述，在这里可以使用空间相对术语，如“在……之上”、“在……上方”、“在……上表面”、“上面的”等，用来描述如在图中所示的一个器件或特征与其他器件或特征的空间位置关系。应当理解的是，空间相对术语旨在包含除了器件在图中所描述的方位之外的在使用或操作中的不同方位。例如，如果附图中的器件被倒置，则描述为“在其他器件或构造上方”或“在其他器件或构造之上”的器件之后将被定位为“在其他器件或构造下方”或“在其他器件或构造之下”。因而，示例性术语“在……上方”可以包括“在……上方”和“在……下方”两种方位。该器件也可以其他不同方式定位(旋转90度或处于其他方位)，并且对这里所使用的空间相对描述作出相应解释。
此外，需要说明的是，使用“第一”、“第二”等词语来限定零部件，仅仅是为了便于对相应零部件进行区别，如没有另行声明，上述词语并没有特殊含义，因此不能理解为对本发明保护范围的限制。
以上所述仅为本申请的优选实施例而已，并不用于限制本申请，对于本领域的技术人员来说，本申请可以有各种更改和变化。凡在本申请的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本申请的保护范围之内。
工业实用性
应用本申请的技术方案，该采集件包括本体、固体采集部以及吸排件。其中，本体具有相对设置的握持端和采集端，采集端设置有采集孔。具体的，固体采集部设置在采集端，吸排件设于与本体的采集端相对的另一端，并与采集孔连通。当需要对粪便进行取样时，利用固体采集部能够定量采集固体样本，通过控制吸排件结合采集孔能够定量吸取或排放液体样本。采用上述结构，该采集件既适合定量采集固态粪便又适合定量采集液态粪便，从而能够提高采集效率，进而满足粪便采集需要。

Claims (14)

  1. 一种采集件，其中，所述采集件包括：
    本体(10)，具有相对设置的握持端和采集端，所述采集端设置有采集孔(11)；
    固体采集部(20)，设置在所述采集端，所述固体采集部(20)用于采集固体样本；
    吸排件(30)，所述吸排件(30)设于与本体的采集端相对的另一端，并与所述采集孔(11)连通，所述吸排件(30)通过所述采集孔(11)吸取或排放液体样本。
  2. 根据权利要求1所述的采集件，其中，所述本体(10)为管状结构，所述管状结构贯穿所述固体采集部(20)。
  3. 根据权利要求2所述的采集件，其中，所述固体采集部(20)包括：
    多个凸壁(21)，多个所述凸壁(21)沿所述采集端的圆周方向间隔设置，相邻两个所述凸壁(21)之间形成样本采集区。
  4. 根据权利要求3所述的采集件，其中，至少一个所述凸壁(21)的表面上设置有通孔(211)，所述通孔(211)与所述样本采集区连通。
  5. 根据权利要求3所述的采集件，其中，所述凸壁(21)具有相对设置的自由端(212)和连接端(213)，所述凸壁(21)的连接端(213)与所述采集端的侧壁连接，所述自由端(212)的厚度小于所述连接端(213)的厚度。
  6. 根据权利要求3所述的采集件，其中，所述凸壁(21)沿远离所述本体(10)的方向弯曲，且每个所述凸壁(21)的弯曲方向相同。
  7. 根据权利要求2所述的采集件，其中，所述固体采集部(20)包括：
    采集壳(22)，套设在所述采集端，所述采集壳(22)内具有采集腔，所述采集壳(22)的表面为多孔结构。
  8. 根据权利要求7所述的采集件，其中，所述采集壳(22)为球形结构。
  9. 一种采集装置，其中，所述采集装置包括：
    采集件，所述采集件为权利要求1至8中任一项所述的采集件；
    混匀管(40)，用于将样本与保存液混合以形成混合液，所述混匀管(40)的一端与所述采集件可拆卸连接。
  10. 根据权利要求9所述的采集装置，其中，所述采集装置还包括：
    盛液管(50)，用于存储保存液或所述混合液，所述盛液管(50)与所述混匀管(40)的另一端可拆卸连接；
    阀体组件(60)，设置在所述混匀管(40)和所述盛液管(50)之间，所述阀体组件 (60)具有打开状态和封闭状态，当所述阀体组件(60)处于所述打开状态时，所述混匀管(40)与所述盛液管(50)导通；当所述阀体组件(60)处于所述封闭状态时，所述混匀管(40)与所述盛液管(50)隔断。
  11. 根据权利要求10所述的采集装置，其中，所述阀体组件(60)包括：
    第一阀体(61)，所述第一阀体(61)的一端与所述混匀管(40)和所述盛液管(50)中的其中一个连接；
    第二阀体(62)，所述第二阀体(62)的一端与所述混匀管(40)和所述盛液管(50)中的另一个连接，所述第二阀体(62)的另一端与所述第一阀体(61)的另一端连接，所述第二阀体(62)具有连通孔(621)，所述连通孔(621)用于连通所述混匀管(40)和所述盛液管(50)；
    封堵组件(63)，设置在所述连通孔(621)处，所述封堵组件(63)具有封堵所述连通孔(621)的封堵位置以及导通所述连通孔(621)的导通位置；
    过滤件(70)，设置在所述封堵组件(63)与所述混匀管(40)之间，或设置在所述封堵组件(63)与所述盛液管(50)之间。
  12. 根据权利要求11所述的采集装置，其中，所述第一阀体(61)和所述第二阀体(62)之间位置可调，通过调节所述第一阀体(61)和所述第二阀体(62)之间的相对位置以驱动所述封堵组件(63)在所述封堵位置和所述导通位置之间移动。
  13. 根据权利要求12所述的采集装置，其中，所述封堵组件(63)包括：
    封堵件(631)，对应所述连通孔(621)设置，所述封堵件(631)具有相对设置的封堵端和抵接端，所述抵接端朝向所述第一阀体(61)设置，所述封堵端朝向所述连通孔(621)设置，所述封堵端用于封堵所述连通孔(621)；
    弹性件(632)，所述弹性件(632)的一端与所述第二阀体(62)连接，所述弹性件(632)的另一端与所述封堵件(631)连接；当所述第一阀体(61)和所述第二阀体(62)相向移动时，所述第一阀体(61)通过所述封堵件(631)挤压弹性件(632)，以使所述封堵件(631)的封堵端移动至封堵位置；当所述第一阀体(61)和所述第二阀体(62)相互远离时，所述弹性件(632)驱动所述封堵件(631)由所述封堵位置移动至所述导通位置。
  14. 根据权利要求13所述的采集装置，其中，所述封堵件(631)包括圆盘本体(631a)和导向柱(631b)，所述导向柱(631b)设置在所述圆盘本体(631a)的朝向所述第二阀体(62)的一侧，所述弹性件(632)套设在所述导向柱(631b)上，所述圆盘本体(631a)上设置有多个滤液孔(631c)，所述圆盘本体(631a)的朝向所述第二阀体(62)的一侧设置有环形凸起(631d)，所述导向柱(631b)位于所述环形凸起(631d)内，所述环形凸起(631d)用于封堵所述连通孔(621)。
PCT/CN2020/089674 2019-05-30 2020-05-11 采集件以及采集装置 WO2020238602A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201910464782.7 2019-05-30
CN201910464782.7A CN111879550A (zh) 2019-05-30 2019-05-30 采集件以及采集装置

Publications (1)

Publication Number Publication Date
WO2020238602A1 true WO2020238602A1 (zh) 2020-12-03

Family

ID=73153779

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2020/089674 WO2020238602A1 (zh) 2019-05-30 2020-05-11 采集件以及采集装置

Country Status (2)

Country Link
CN (1) CN111879550A (zh)
WO (1) WO2020238602A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112858273B (zh) * 2021-01-13 2023-04-21 上海玄元医疗科技有限公司 智慧医院用犬降钙素原检测试剂盒、适配的检测装置

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2372683Y (zh) * 1999-04-15 2000-04-05 郭莉 大便采集管
US20160338678A1 (en) * 2015-05-20 2016-11-24 Alpha-Tec Systems, Inc. Sample collection apparatus
CN207007540U (zh) * 2017-06-18 2018-02-13 张巍巍 一次性采便器
CN207336102U (zh) * 2017-08-29 2018-05-08 杭州同创越诚基因科技有限公司 粪便样本定量采集装置
CN207528471U (zh) * 2017-11-14 2018-06-22 上海市杨浦区中心医院 新型粪便采集处理器
CN108414263A (zh) * 2018-05-04 2018-08-17 上海透景诊断科技有限公司 粪便样本一体化采集装置及方法
CN210442125U (zh) * 2019-05-30 2020-05-01 深圳微伴生物有限公司 采集件以及采集装置

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2372683Y (zh) * 1999-04-15 2000-04-05 郭莉 大便采集管
US20160338678A1 (en) * 2015-05-20 2016-11-24 Alpha-Tec Systems, Inc. Sample collection apparatus
CN207007540U (zh) * 2017-06-18 2018-02-13 张巍巍 一次性采便器
CN207336102U (zh) * 2017-08-29 2018-05-08 杭州同创越诚基因科技有限公司 粪便样本定量采集装置
CN207528471U (zh) * 2017-11-14 2018-06-22 上海市杨浦区中心医院 新型粪便采集处理器
CN108414263A (zh) * 2018-05-04 2018-08-17 上海透景诊断科技有限公司 粪便样本一体化采集装置及方法
CN210442125U (zh) * 2019-05-30 2020-05-01 深圳微伴生物有限公司 采集件以及采集装置

Also Published As

Publication number Publication date
CN111879550A (zh) 2020-11-03

Similar Documents

Publication Publication Date Title
US5422273A (en) Cell collection apparatus
KR101366657B1 (ko) 검체 용기
US3190731A (en) Sample-supply cups for analysis apparatus
US5370128A (en) Pap brush and pap unit container systems
US4378333A (en) Device for preparing blood smears on glass slides and method therefor
WO2020238602A1 (zh) 采集件以及采集装置
CN111203292B (zh) 一种微量移液器及移液方法
US20130109009A1 (en) Biological sample preparation
KR100661488B1 (ko) 각종 암검사를 위한 액상세포검진장치
CN210442125U (zh) 采集件以及采集装置
JPS6240283A (ja) 可搬培養基移送装置
CN108722517A (zh) 一种便携式移液枪枪头快速装盒器
KR101170018B1 (ko) 세포 분산용 블럭 및 이를 이용한 세포 검사 도말을 위한 검체 처리 용기 어셈블리
WO2020238601A1 (zh) 采集组件以及采集装置
DE102010036216B4 (de) Vorrichtung zum Transfer von mittels Probennehmer gesammelter Proben in fluidische Plattformen
JP2005238158A (ja) 遠心管
CN112638534A (zh) 用于储存和涂抹脱落细胞的瓶装置
CN213726594U (zh) 定量式取样试管
RU2774921C1 (ru) Пробирка для хранения и размазывания слущенных клеток
CN209400247U (zh) 粪便定量取样装置
CN211148054U (zh) 采集组件以及采集装置
US8034307B2 (en) Filter for automated slide preparation system
CN109490005A (zh) 粪便定量取样装置
CN215586802U (zh) 一种用于流式细胞分析用的细胞分离装置
CN215811992U (zh) 拉曼光谱检测用样本混匀加样装置

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20812624

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 20812624

Country of ref document: EP

Kind code of ref document: A1