WO2020137492A1 - Dispositif médical de traitement chauffant - Google Patents

Dispositif médical de traitement chauffant Download PDF

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Publication number
WO2020137492A1
WO2020137492A1 PCT/JP2019/048102 JP2019048102W WO2020137492A1 WO 2020137492 A1 WO2020137492 A1 WO 2020137492A1 JP 2019048102 W JP2019048102 W JP 2019048102W WO 2020137492 A1 WO2020137492 A1 WO 2020137492A1
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WO
WIPO (PCT)
Prior art keywords
moisture
medical device
permeable sheet
sole
generating part
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PCT/JP2019/048102
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English (en)
Japanese (ja)
Inventor
孝太 中林
哲也 丸山
Original Assignee
小林製薬株式会社
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Application filed by 小林製薬株式会社 filed Critical 小林製薬株式会社
Priority to CN201980077876.7A priority Critical patent/CN113164279A/zh
Publication of WO2020137492A1 publication Critical patent/WO2020137492A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction

Definitions

  • the present invention relates to a medical device for hyperthermia treatment that can impart a thermal effect to the whole body without using a power source.
  • the thermal effect is the effect of warming the body by giving energy from the heat source to the human body, which results in therapeutic effects such as promoting blood circulation, improving fatigue, improving muscle stiffness, and activating gastrointestinal function.
  • various medical devices for hyperthermia treatment for imparting a hyperthermic effect have been developed (for example, Patent Document 1).
  • thermotherapy has a drawback in that it is only possible to locally apply the heating effect to the body, and the effect of applying the heating effect to the entire body is poor.
  • An object of the present invention is to provide a medical device for hyperthermia treatment that can impart a thermal effect to the whole body without using a power source.
  • the present inventor has conducted diligent studies to solve the above-mentioned problems.
  • a heat-generating part containing reduced iron powder as an oxidizing metal is used, and the moisture permeability is 300 to 1200 g/m 2 ⁇ day.
  • the medical device for thermotherapy contained in a container including a sheet by disposing it in at least a part of the sole, a thermal effect is given to the entire body, and not only the sole, but also the hands, feet, It was found that blood circulation is promoted in the whole body such as the shoulder.
  • the present invention has been completed by further studies based on such findings.
  • Item 1 A medical device for hyperthermia which is used by being disposed on at least a part of the sole of the foot, A heat generating part that generates heat that is transferred to the sole of the foot, And a container containing the heat generating part and including a moisture-permeable sheet on at least one surface thereof, The heat generating part contains reduced iron powder, and the moisture permeability of the moisture permeable sheet is 300 to 1200 g/m 2 ⁇ day. Medical device for hyperthermia treatment.
  • Item 2. The medical device for hyperthermia treatment according to Item 1, wherein the exothermic part further contains an oxidation promoter and water.
  • Item 3. Item 3.
  • the medical device for thermotherapy according to Item 1 or 2 wherein the moisture-permeable sheet is a laminated sheet of a breathable resin layer having pores and a fiber base material.
  • Item 4. The medical device for thermotherapy according to any one of Items 1 to 3, wherein an adhesive layer is provided on one surface of the container.
  • Item 5. The medical device for hyperthermia treatment according to any one of Items 1 to 4, which is used for imparting a thermal effect to the entire body. Item 6.
  • the chemical body warmer A heat generating part that generates heat that is transferred to the sole of the foot, And a container containing the heat generating part and including a moisture-permeable sheet on at least one surface thereof,
  • the heat generating part contains reduced iron powder, and the moisture permeability of the moisture permeable sheet is 300 to 1200 g/m 2 ⁇ day. Said use. Item 7.
  • thermotherapy method comprising the step of disposing a chemical warmer on at least a part of the sole of a person who requires hyperthermia,
  • the chemical body warmer A heat generating part that generates heat that is transferred to the sole of the foot,
  • the heat generating part contains reduced iron powder, and the moisture permeability of the moisture permeable sheet is 300 to 1200 g/m 2 ⁇ day.
  • the medical device for hyperthermia of the present invention by applying to the sole of the foot, it is possible to promote blood circulation in the hands, feet, shoulders, etc., and it is possible to impart a heating effect to the whole body, and to cool the whole body. Improvement, swelling improvement, fatigue recovery, muscle pain relief, joint pain relief, immunity enhancement, muscle stiffness relief, etc. become possible. Further, the medical device for hyperthermia treatment of the present invention does not require an electric power source to impart the thermal effect, and therefore is excellent in convenience and versatility.
  • A is a schematic plan view of the moisture-permeable sheet and the moisture-impermeable sheet used in the test example.
  • B is the schematic which planarly viewed the medical device for thermotherapy manufactured in the test example.
  • FIG. 3A is a schematic view of the sticking sample used in the test example as seen from the side of the medical device for thermotherapy.
  • B is the schematic diagram which planarly viewed from the double-sided tape side the sticking sample used in the test example.
  • the medical device for thermotherapy of the present invention is a medical device for thermotherapy which is used by being disposed on at least a part of a sole, and a heat generating part for generating heat transferred to the sole, and the heat generating part. And a container containing a moisture permeable sheet on at least one surface thereof, the heat generating portion contains reduced iron powder, and the moisture permeability of the moisture permeable sheet is 300 to 1200 g/m 2 ⁇ day. It is characterized by being a chemical warmer.
  • the medical device for thermotherapy of the present invention will be described in detail.
  • the medical device for hyperthermia treatment of the present invention has a heat generating portion containing reduced iron powder in order to generate heat transferred to the sole.
  • reduced iron powder as an oxidizable metal that generates heat of oxidation by contact with oxygen, and by using a container having a specific moisture permeability described later, it is arranged on at least a part of the sole. When used, it becomes possible to give a thermal effect to the whole body.
  • the “heat-generating part” is a part that generates heat to be transmitted to the sole of the foot, and is composed of a heat-generating composition containing an oxidizable metal and other components that are optionally mixed.
  • ⁇ Reduced iron powder is powdered iron produced by reducing iron compounds such as iron oxide and iron salts with hydrogen.
  • the range of the particle size of the reduced iron powder used in the present invention is not particularly limited, but examples thereof include more than 10 ⁇ m and 800 ⁇ m or less. From the viewpoint of further improving the heating effect on the whole body, the particle size of the reduced iron powder is preferably more than 10 ⁇ m and 500 ⁇ m or less, and more preferably more than 10 ⁇ m and 300 ⁇ m or less. In the present invention, the range of the particle size of the reduced iron powder is a value determined according to the method specified in the Japanese Industrial Standard “JIS 8815-1994 General Rules for Sifting Test Method”.
  • the apparent density of the reduced iron powder used in the present invention is not particularly limited, but is, for example, 1.0 to 4.0 g/cm 2 , preferably 1.5 to 4.0 g/cm 2 , and more preferably 2.0 to 4.0 g/cm 2 can be mentioned.
  • the apparent density is a value determined according to the method specified in Japanese Industrial Standard “JIS Z 2504:2012 Metal powder-Apparent density measuring method”.
  • the content of the reduced iron powder in the heat generating part is, for example, 20 to 80% by weight, preferably 25 to 70% by weight, more preferably 30 to 60% by weight.
  • the heat generating part may contain an oxidation promoter for holding oxygen and for promoting oxygen supply to the reduced iron powder.
  • the type of the oxidation promoter is not particularly limited as long as it is capable of retaining oxygen and supplying oxygen to the reduced iron powder, but examples thereof include activated carbon, carbon black, acetylene black, bamboo charcoal, charcoal, coffee ground charcoal. , Carbon materials such as graphite, coal, coconut shell charcoal, calendar blue coal, peat and lignite. These oxidation promoters may be used alone or in combination of two or more.
  • activated carbon preferred are activated carbon, carbon black, bamboo charcoal, charcoal, coffee dust charcoal, and more preferably activated carbon.
  • the shape of the oxidation promoter is not particularly limited, but from the viewpoint of heat generation efficiency, it is preferably powdery, granular or fibrous, and more preferably powdery.
  • the content of the oxidation promoter in the heat generating part is not particularly limited, but is, for example, 1 to 30% by weight, preferably 3 to 25% by weight, more preferably 5 to 23% by weight. %.
  • the heat generating part contains water in order to accelerate the oxidation reaction of the reduced iron powder.
  • water any of distilled water, ion-exchanged water, pure water, ultrapure water, tap water, industrial water, etc. may be used.
  • the content of water in the heat-generating part is not particularly limited, but is, for example, 5 to 50% by weight, preferably 10 to 40% by weight, more preferably 15 to 35% by weight. ..
  • the heat generating part may contain a water retention agent in order to retain water and efficiently supply water to the oxidation reaction field.
  • the type of the water retention agent is not particularly limited, but for example, vermiculite (calculus), perlite, calcium silicate, magnesium silicate, kaolin, talc, smectite, mica, bentonite, calcium carbonate, silica gel, alumina, zeolite, dioxide.
  • Inorganic porous materials such as silicon and diatomaceous earth; organic substances such as pulp, wood powder (sawdust), cotton, starches, celluloses; polyacrylic acid resins, polysulfonic acid resins, maleic anhydride resins, polyacrylamide resins
  • water absorbent resins such as polyvinyl alcohol resins, polyethylene oxide resins, polyaspartic acid resins, polyglutamic acid resins, and polyalginic acid resins.
  • water retention agents preferably vermiculite, polyacrylic acid-based resin, wood powder, pulp; more preferably vermiculite, polyacrylic acid-based resin. Further, when an inorganic porous material is used as the water retention agent, it becomes possible to secure an air flow path in the exothermic composition.
  • the content of the water retention agent in the heat generating part is not particularly limited, but is, for example, 1 to 20% by weight, preferably 3 to 15% by weight, and further preferably Is 3 to 7% by weight.
  • the exothermic part may contain water-soluble salts in order to accelerate the oxidation reaction of the reduced iron powder.
  • the type of water-soluble salt is not particularly limited, but examples thereof include alkali metals (sodium, potassium, etc.), alkaline earth metals (calcium, magnesium, etc.), or heavy metals (iron, copper, aluminum, zinc, nickel, silver, Sulfates, hydrogen carbonates, chlorides or hydroxides of barium).
  • chlorides such as sodium chloride, potassium chloride, calcium chloride, magnesium chloride, iron chloride (first and second) are more preferable, from the viewpoints of conductivity, chemical stability, and the like, and further preferable.
  • Examples include sodium chloride.
  • These water-soluble salts may be used alone or in combination of two or more.
  • the content of the water-soluble salt in the heat-generating part is not particularly limited, but is, for example, 0.1 to 10% by weight, preferably 0.5 to 7% by weight, and more preferably 0.5 to 5% by weight.
  • additives such as a metal to be oxidized other than the reduced iron powder, a sequestering agent, a fragrance, a thickener, an excipient, a surfactant, a hydrogen generation inhibitor, etc. may be added. May be included.
  • the exothermic composition used as the exothermic part can be prepared by mixing the above-mentioned components in predetermined amounts.
  • the exothermic composition used as the exothermic part may be prepared in the presence of oxygen, but is preferably prepared under reduced pressure or in an inert gas atmosphere.
  • the amount of the heat-generating part accommodated in each container may be appropriately set within the range applicable to the sole, but is preferably 5 to 30 g, preferably Is 10 to 20 g, more preferably 12 to 18 g.
  • the medical device for hyperthermia treatment of the present invention has a container for housing the heat generating portion.
  • the container is a moisture permeable sheet having a moisture permeability of 300 to 1200 g/m 2 ⁇ day on at least one surface in order to supply oxygen and water vapor to the heat generating portion during use. have.
  • the moisture permeability of the moisture-permeable sheet used in the present invention may be 300 to 1200 g/m 2 ⁇ day. It is preferably 650 to 1200 g/m 2 ⁇ day, more preferably 680 to 1150 g/m 2 ⁇ day, and particularly preferably 700 to 1100 g/m 2 ⁇ day.
  • the water vapor transmission rate is measured under the conditions of a temperature of 40° C. and a humidity of 90% RH by the method specified in Japanese Industrial Standard “JIS Z0208-1975 Moisture vapor transmission test method (cup method) for moisture-proof packaging materials. It is a value.
  • the material of the moisture-permeable sheet is not particularly limited as long as it has the moisture permeability, but it is preferable that it is formed of at least a breathable resin layer (resin layer having pores) to improve the usability. From this point of view, a laminated sheet of a breathable resin layer and a fiber base material is more preferable. In the laminated sheet of the air-permeable resin layer and the fiber base material, the air-permeable resin layer and the fiber base material may be laminated in this order from the inside to the outside of the container.
  • the constituent resin of the gas permeable resin layer is not particularly limited, and examples thereof include polyethylene, polypropylene, ethylene-vinyl acetate copolymer, polyethylene terephthalate, polyacrylonitrile, ethylene-vinyl alcohol copolymer, polyamide, polyurethane, polystyrene, polyvinyl.
  • examples thereof include alcohol, polyvinyl chloride, polyvinylidene chloride, and polycarbonate.
  • polyethylene, polypropylene and ethylene vinyl acetate copolymer are preferable.
  • the breathable resin layer may be a resin film provided with pores for ensuring breathability.
  • the shape, size and number of the pores provided in the resin film may be appropriately set according to the moisture permeability to be provided in the container.
  • the thickness of the breathable resin layer may be appropriately set according to the layer structure of the moisture permeable sheet, and is, for example, 15 to 150 ⁇ m, preferably 30 to 100 ⁇ m, and more preferably 50 to 80 ⁇ m.
  • the fiber base material used for the moisture permeable sheet include non-woven fabric and woven fabric. From the viewpoint of usability, a non-woven fabric is preferable.
  • the material of the fiber base material 232 is not particularly limited, but for example, synthetic fibers such as polyethylene terephthalate, polybutylene terephthalate, nylon, polypropylene, polyethylene, vinylon, rayon, acrylic, acetate, polyvinyl chloride; cotton, hemp, silk. , Natural fibers such as paper; and mixed fibers thereof.
  • synthetic fibers such as polyethylene terephthalate, polybutylene terephthalate, nylon, polypropylene, polyethylene, vinylon, rayon, acrylic, acetate, polyvinyl chloride; cotton, hemp, silk.
  • Natural fibers such as paper; and mixed fibers thereof.
  • polyethylene terephthalate, nylon and polypropylene are preferable, and polyethylene terephthalate and nylon are more preferable, from the viewpoint of enhancing the feeling of use.
  • the basis weight of the fibrous base material may be appropriately set according to the layer structure of the moisture-permeable sheet and the like, but is, for example, 1 to 100 g/m 2 , preferably 5 to 70 g/m 2 , and more preferably 10 to 50 g/m 2 . m 2 may be mentioned.
  • the air-permeable resin layer and the fiber base material can be laminated by a known laminating method such as dry laminating, extrusion laminating or heat laminating.
  • the container used in the present invention may include the moisture-permeable sheet on at least one surface.
  • the container used in the present invention preferably has a shape having two surfaces, a surface arranged on the sole side and a surface arranged on the opposite side. In the case of having the shape, the entire surface may be formed of the moisture permeable sheet, and one surface is the moisture permeable sheet, and the other surface is a low moisture permeable sheet (hereinafter referred to as “non-moisture permeable sheet”). May be described).
  • the moisture permeability of the moisture-impermeable sheet for example 10g / m 2 ⁇ day or less, preferably 5g / m 2 ⁇ day or less, more preferably 2g / m 2 ⁇ day or less, more preferably 1g / m 2 ⁇ day Below, 0 g/m 2 ⁇ day is particularly preferable.
  • the material of the non-moisture permeable sheet is not particularly limited, but a resin sheet having no pores is preferable.
  • the constituent resin of the resin sheet constituting the non-moisture permeable sheet is not particularly limited, and examples thereof include polyethylene, polypropylene, ethylene-vinyl acetate copolymer, polyethylene terephthalate, polyacrylonitrile, ethylene-vinyl alcohol copolymer, polyamide, Examples thereof include polyurethane, polystyrene, polyvinyl alcohol, polyvinyl chloride, polyvinylidene chloride, and polycarbonate.
  • polyethylene, polypropylene and ethylene vinyl acetate copolymer are preferable.
  • the thickness of the resin sheet forming the non-moisture permeable sheet may be appropriately set according to the layer structure of the non-moisture permeable sheet, and is, for example, 115 to 250 ⁇ m, preferably 130 to 200 ⁇ m, more preferably 150 to 180 ⁇ m can be mentioned.
  • the non-moisture permeable sheet may have a fiber base material laminated on a resin sheet having no pores, if necessary.
  • the material and basis weight of the fiber base material used in the non-moisture permeable sheet are the same as those exemplified for the moisture permeable sheet.
  • one surface of the container is preferably provided with an adhesive layer so that it can be fixed to the sole of the foot when used.
  • an adhesive layer is provided on the surface of one moisture permeable sheet, and one surface is a moisture permeable sheet, and the other surface is When formed of a non-moisture permeable sheet, an adhesive layer may be provided on the surface of the non-moisture permeable sheet.
  • the adhesive layer may be provided on the entire one surface of the container, or may be partially provided on one surface of the container.
  • the adhesive layer can be formed using an adhesive.
  • the adhesive includes a polymer (adhesive polymer) that exhibits adhesiveness in the presence of an oil agent or other solvent, and the adhesive polymer is dispersed or dissolved in the oil agent or other solvent to exhibit adhesiveness.
  • the composition The type and composition of the adhesive polymer contained in the adhesive are known, and in the present invention, the adhesive used in the adhesive layer of the conventional disposable body warmer can be used. Specific examples of the type of adhesive include rubber-based adhesives, acrylic-based adhesives, silicone-based adhesives, urethane-based adhesives, and the like.
  • the coating amount of the adhesive layer is, for example, 5 to 40 g/m 2 , preferably 10 to 30 g/m 2 , and more preferably 15 to 25 g/m 2 .
  • a release layer capable of releasing may be provided on the outer surface of the adhesive layer.
  • the release layer it is possible to prevent the adhesive layer from being dried during storage and prevent the handling property from being deteriorated due to the adhesion of the adhesive layer.
  • the release layer examples include resin films such as polyethylene terephthalate, polyacrylonitrile, ethylene-vinyl alcohol copolymer, and polypropylene; paper that has been subjected to a release property imparting treatment such as silicone processing. Further, even when the resin film is used as the release layer, the release property imparting process such as silicone process may be applied.
  • the container has a shape composed of two surfaces, a surface arranged on the sole side and a surface arranged on the opposite side, the two moisture-permeable sheets or the one moisture-permeable sheet and the one sheet It is formed by sticking one non-moisture permeable sheet around the area for accommodating the heat generating portion.
  • the method for laminating the two moisture-permeable sheets or the one moisture-permeable sheet and the one non-moisture permeable sheet is not particularly limited, but, for example, the moisture-permeable resin or the non-moisture permeable sheet may be attached to the heat-welding resin.
  • the ends may be heat-welded (heat-sealed) by using the heat-fusible resin, or the ends may be bonded by using an adhesive.
  • the shape of the container may be set so that it can be disposed on at least a part of the bottom of the foot, and may be appropriately set according to the part of the foot to be applied.
  • the shape in plan view extends from the linear end side in one direction.
  • a shape in which the other end side is circular is mentioned.
  • the surface of the container disposed on the side of the sole may be provided with a concave portion or a convex portion so as to follow the shape of the sole. ..
  • the area of the portion that accommodates the heat generating portion in the container is, for example, 20 to 180 cm 2 , preferably 30 to 70 cm 2 , and more preferably 35-60 cm 2 can be mentioned.
  • the medical device for hyperthermia treatment of the present invention is packaged in a packaging material having an oxygen barrier property and provided without contact with air. By disposing it on at least a part of the sole during use, the heat generating part comes into contact with the air and heat generation starts.
  • the medical device for hyperthermia treatment of the present invention is used by being disposed on at least a part of the sole.
  • the medical device for hyperthermia of the present invention can be locally applied to at least a part of the sole of the foot to impart a heating effect to the whole body such as hands, feet, and shoulders.
  • the medical device for hyperthermia of the present invention can impart a thermal effect to the whole body, it promotes blood circulation in the whole body, improves coldness, improves tiredness, improves muscle stiffness, and activates gastrointestinal function. It can be used for the purpose of immunostimulation.
  • the medical device for hyperthermia treatment of the present invention may be used by directly fixing it to the skin on the sole of the foot, or by fixing it to the sole of the foot while wearing socks. Further, the medical device for thermotherapy of the present invention can be used by fixing it to the insole of shoes or slippers and putting on the shoes or slippers.
  • the site of the plantar part to which the medical device for hyperthermia treatment of the present invention is applied is not particularly limited, and examples thereof include the back of the toes, the base of the back of the toes, the arch, the small flexor flexor portion, and the heel.
  • the medical device for hyperthermia treatment of the present invention may be designed so as to be arranged on at least a part of the sole of the foot, and for example, together with a part of the bottom of the foot, a front part of a toe or a foot It may be designed so as to be arranged also on at least a part of the instep.
  • the part of the sole of the foot where the medical device for thermotherapy of the present invention is arranged, preferably at least the base part of the back of the toes, more preferably the foot. At least a part of the back of the toes and the base of the back of the toes, and particularly preferably, the sole of the region from about 0 to 1 cm from the tip of the middle toe to about 9 to 20 cm toward the heel side.
  • the moisture-permeable sheets A to F having various moisture permeability shown in Table 1 were prepared .
  • the shape of each moisture permeable sheet is as shown in FIG.
  • the moisture permeability of each moisture permeable sheet is measured under the conditions of temperature 40° C. and humidity 90% RH by the method specified in Japanese Industrial Standard “JIS Z0208-1975 moisture proof packaging material moisture permeability test method (cup method)”.
  • a spunlace nonwoven fabric made of polyethylene terephthalate weight per unit area: 30 g/m 2
  • a polyethylene film thickness 60 ⁇ m
  • a non-moisture permeable sheet (thickness 159 ⁇ m) having a moisture permeability of 0 g/m 2 ⁇ day was prepared.
  • the shape of the moisture impermeable sheet is as shown in A of FIG.
  • a pressure-sensitive adhesive was applied to one surface of the non-moisture permeable sheet at a rate of 21 g/m 2, and then a release sheet was laminated.
  • the iron powder A was prepared by classifying iron powder (“MR2” (manufactured by Dowa Iron Powder Industry Co., Ltd.) with a mesh having an opening of 180 ⁇ m, and collecting the iron powder remaining on the mesh.
  • B was prepared by classifying iron powder (“MR2”, (manufactured by Dowa Iron Powder Industry Co., Ltd.) with a mesh having an opening of 45 ⁇ m, and collecting the iron powder that passed through the mesh.
  • Powder (“80AF”, (manufactured by Kobe Steel, Ltd.) was used.
  • iron powder D the iron powder (“80AF”, (manufactured by Kobe Steel, Ltd.) was classified by a mesh having an opening of 180 ⁇ m, and the mesh was used. It was prepared by recovering the iron powder remaining in No. 1. The apparent density was measured by the method specified in Japanese Industrial Standards "JIS Z 2504:2012 Metal powder-Apparent density measuring method".
  • An exothermic composition having the composition shown in Table 3 was prepared using each of the iron powders and used as a heating element.
  • the non-woven fabric side of the moisture permeable sheet and the pressure-sensitive adhesive layer laminated on the non-moisture permeable sheet were arranged such that they were on the outside, and the prepared heating element 13g was sandwiched between the moisture permeable sheet and the non-moisture permeable sheet. ..
  • the peripheral edge portion (width 0.5 cm) of both sheets is heat-welded so as to be as shown in FIG. 2B in a plan view, and a medical device for thermotherapy having a heating element housed in the housing portion. It was manufactured (the black line portion surrounding the periphery in B of FIG.
  • the peripheral portion which is heat-sealed is the peripheral portion which is heat-sealed).
  • the area of the part that accommodates the heat generating portion (the area of the part that accommodates the heat generating portion in plan view) is 57 cm 2 .
  • the medical device for hyperthermia treatment that was manufactured was quickly housed and sealed in a gas-impermeable sealed bag.
  • the combinations of the moisture-permeable sheet and the iron powder used in the heating element in the manufactured medical device for thermotherapy are as shown in Table 4.
  • the portion of the apex X shown in FIG. 3A is located 1 cm from the tip of the middle finger of the left sole from the heel, and the apex X is on the finger side and the end side Y is on the heel side.
  • the sample for sticking was stuck to the region of the base from the back of the toes through the tape, and the state was maintained for 60 minutes.
  • blood flow blood after attachment
  • the foot the ankle part of the right foot
  • the hand the back part of the right shoulder
  • the shoulder the back part of the right shoulder
  • Flow was measured with a Doppler blood flow meter.
  • the amount of change in blood flow after use was calculated by subtracting the value of blood flow before application from the value of blood flow after application.
  • the attachment site of the attachment sample was changed to the heel of the left sole, and blood flow was measured by the same method.
  • the apex X shown in FIG. 3A is arranged on the apex side of the heel and the end side Y is arranged on the toe side.
  • the attachment site of the attachment sample was changed to the left shoulder, and blood flow was measured by the same method.
  • the sticking sample is stuck to the left shoulder
  • the apex X shown in FIG. 3A is arranged on the neck side of the left shoulder and the end side Y is arranged on the left arm side.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Thermal Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

Le but de la présente invention est de fournir un dispositif médical de traitement chauffant qui est capable de conférer un effet chauffant à l'ensemble du corps sans utiliser de source d'alimentation.　Ce dispositif médical de traitement chauffant utilise une partie chauffante qui contient une poudre de fer réductrice en tant que métal oxydable, la partie chauffante étant logée dans un corps de boîtier qui comprend une feuille perméable à l'humidité qui a une perméabilité à l'humidité de 300 à 1 200 g/m2∙jour. Lorsque le dispositif médical de traitement chauffant est utilisé tout en étant agencé au moins au niveau d'une partie des plantes des pieds, un effet chauffant est appliqué à l'ensemble du corps et la circulation sanguine est favorisée non seulement dans les plantes des pieds mais également à tout le corps y compris les mains, les jambes et les épaules.
PCT/JP2019/048102 2018-12-28 2019-12-09 Dispositif médical de traitement chauffant WO2020137492A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201980077876.7A CN113164279A (zh) 2018-12-28 2019-12-09 温热治疗用的医疗设备

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JP2018-248612 2018-12-28
JP2018248612A JP7343975B2 (ja) 2018-12-28 2018-12-28 温熱治療用の医療機器

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WO2020137492A1 true WO2020137492A1 (fr) 2020-07-02

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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