WO2020105580A1 - Dialysis device cleaning system - Google Patents

Dialysis device cleaning system

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Publication number
WO2020105580A1
WO2020105580A1 PCT/JP2019/045046 JP2019045046W WO2020105580A1 WO 2020105580 A1 WO2020105580 A1 WO 2020105580A1 JP 2019045046 W JP2019045046 W JP 2019045046W WO 2020105580 A1 WO2020105580 A1 WO 2020105580A1
Authority
WO
WIPO (PCT)
Prior art keywords
flow path
electrolyzed water
stock solution
water
cleaning
Prior art date
Application number
PCT/JP2019/045046
Other languages
French (fr)
Japanese (ja)
Inventor
篤 藤井
悦孝 山下
Original Assignee
ニプロ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ニプロ株式会社 filed Critical ニプロ株式会社
Priority to JP2020558371A priority Critical patent/JP7314956B2/en
Publication of WO2020105580A1 publication Critical patent/WO2020105580A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/1657—Apparatus for preparing dialysates with centralised supply of dialysate or constituent thereof for more than one dialysis unit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes

Definitions

  • the present invention relates to a dialysis machine cleaning system.
  • Patent Document 1 JP-A-7-284744
  • the outflow passage of the acidic electrolyzed water and the outflow passage of the alkaline electrolyzed water are connected to the four-way valve together with the outflow passage of the reverse osmosis water from the reverse osmosis water tank.
  • the fluid selected by the four-way valve is supplied by a pump to a central feeder, which then feeds a dialysis monitor.
  • alkaline electrolyzed water when cleaning the dialysis machine, alkaline electrolyzed water, reverse osmosis water, and acid electrolyzed water are sequentially sent to the central supply unit.
  • the acidic electrolyzed water is a hypochlorous acid aqueous solution.
  • the dialyzer cleaning system may include a reverse osmosis water circulation channel. Since reverse osmosis water does not contain chlorine, it is necessary to clean the circulation channel in order to suppress the growth of bacteria in the circulation channel. Unlike the dialysate flow channel, the circulation flow channel does not flow a substance such as a protein component, so that it is not necessary to wash with acidic electrolyzed water having a high acidity. As in the case of cleaning the dialysis device, when the circulation flow passage is washed with acidic electrolyzed water having a high acidity, that is, a high concentration aqueous solution of hypochlorous acid, the circulation flow passage deteriorates.
  • the present invention has been made in view of the above problems, and it is possible to wash the circulation flow path of reverse osmosis water with acidic electrolyzed water having a lower concentration of hypochlorous acid than acidic electrolyzed water for washing a dialysis machine. , A dialyzer cleaning system is provided.
  • a dialysis machine cleaning system based on the present invention includes a circulation flow path, a reverse osmosis water generation apparatus, a dialysis machine, a first supply flow path, an electrolyzed water generation apparatus, a first bypass flow path, and a second bypass flow path.
  • the circulation channel circulates the reverse osmosis water in one direction.
  • the reverse osmosis water generation device is provided in the circulation flow channel and can supply the reverse osmosis water to the circulation flow channel.
  • the dialyzer is directly or indirectly connected to the circulation channel.
  • the first supply channel connects the circulation channel and the dialysis device to each other.
  • the electrolyzed water generation device can take in the reverse osmosis water flowing through the circulation flow path to generate the electrolysis water for cleaning, and can supply the electrolysis water for cleaning to the first supply flow path.
  • the first bypass flow path connects the circulation flow path and the electrolyzed water generating device to each other.
  • the second bypass flow passage connects the electrolyzed water generating device and the first supply flow passage to each other.
  • the first on-off valve is provided in the circulation flow path, downstream of the connection with the first bypass flow path and upstream of the connection with the first supply flow path.
  • the second opening / closing valve is provided in the first supply passage between the connection portion with the circulation passage and the connection portion with the second bypass passage.
  • a dialyzer cleaning system includes a dialysate preparation device, a first stock solution tank, a second stock solution tank, a second supply passage, a third bypass passage, and a third opening / closing valve. And a fourth opening / closing valve.
  • the dialysate preparation device is provided in the first supply channel on the dialyzer side with respect to the connection portion with the second bypass channel.
  • the first stock solution tank is connected to the dialysate preparation apparatus and supplies the first stock solution to the dialysate preparation apparatus.
  • the second stock solution tank is connected to the dialysate preparation apparatus and supplies the second stock solution to the dialysate preparation apparatus.
  • the second supply flow path connects the circulation flow path to each of the first stock solution tank and the second stock solution tank.
  • the third bypass flow passage connects the electrolyzed water generation device and the second supply flow passage to each other.
  • the third opening / closing valve is provided in the second supply passage on the circulation passage side from the connection portion with each of the first stock solution tank, the second stock solution tank, and the third bypass flow path.
  • the fourth opening / closing valve is provided in the third bypass passage.
  • the dialysis machine cleaning system further includes a neutralization pipe.
  • the neutralization pipe is connected to the electrolyzed water generating device and discharges the electrolyzed neutralizing water that is not the electrolyzed water for cleaning out of the acidic electrolyzed water and the alkaline electrolyzed water generated in the electrolyzed water generator.
  • the neutralizing pipe is configured such that the neutralizing electrolytic water discharged from the neutralizing pipe joins with the cleaning electrolytic water discharged from the dialyzer.
  • the circulation passage of reverse osmosis water can be washed with acidic electrolyzed water having a lower concentration of hypochlorous acid than the acidic electrolyzed water for washing the dialysis machine.
  • FIG. 4 is a circuit diagram showing a state in which the tank in the reverse osmosis water generator is being washed in the dialysis machine washing system according to the embodiment of the present invention. It is a circuit diagram which shows the state which is performing strong acid washing in the dialysis machine washing system which concerns on one Embodiment of this invention. It is a circuit diagram which shows the state which is hot water washing
  • FIG. 1 is a circuit diagram showing a state in which dialysis is being performed in the dialysis machine cleaning system according to the embodiment of the present invention.
  • the upstream side and the downstream side in the fluid flow direction in the state of performing dialysis may be simply referred to as “upstream side” and “downstream side”, respectively.
  • a dialysis device cleaning system 100 includes a circulation flow channel 110, a reverse osmosis water generation device 120, a dialysis device 130, a first supply flow channel 131, and an electrolysis.
  • the neutralization pipe 180 does not necessarily have to be provided.
  • the circulation channel 110 circulates reverse osmosis water in one direction.
  • the reverse osmosis water circulating in the circulation channel 110 is used as a raw material for the dialysate.
  • the circulation channel 110 is mainly made of stainless steel. If acidic electrolyzed water having a high concentration of hypochlorous acid is circulated through the circulation passage 110 during the cleaning of the dialysis device 130, the portion of the circulation passage 110 made of stainless steel is When it is exposed to acidic electrolyzed water having a high concentration of chlorous acid for a long time, it corrodes and deteriorates over time.
  • the reverse osmosis water generation device 120 is provided in the circulation flow channel 110.
  • the reverse osmosis water generation apparatus 120 is configured to pass through the reverse osmosis water generation apparatus 120 twice when the reverse osmosis water makes one round in the circulation flow channel 110.
  • the reverse osmosis water generation apparatus 120 has a tank internally connected to the circulation flow channel 110.
  • a raw water supply unit 121 is connected to the reverse osmosis water generator 120.
  • the reverse osmosis water generation device 120 generates reverse osmosis water by allowing a part of the raw water supplied from the raw water supply unit 121 to pass through the reverse osmosis membrane.
  • the reverse osmosis water generation device 120 can supply the generated reverse osmosis water to the circulation channel 110.
  • the raw material water may be tap water or purified water.
  • the reverse osmosis water generation device 120 has a heater.
  • the reverse osmosis water generation apparatus 120 can heat the reverse osmosis water flowing through the circulation channel 110 by the heater. By heating the reverse osmosis water, the dialysate prepared using the reverse osmosis water as a raw material can be brought to a temperature close to the body temperature.
  • the reverse osmosis water generator 120 may not have a heater.
  • the dialysis device 130 is directly or indirectly connected to the circulation channel 110.
  • the dialysis device 130 is indirectly connected to the circulation flow channel 110.
  • the dialyser 130 is supplied with a dialysate prepared using reverse osmosis water flowing through the circulation channel 110.
  • the dialyzer 130 When the dialyzer 130 is configured to be able to prepare a dialysate, the dialyzer 130 may be directly connected to the circulation flow channel 110. Further, as shown in FIG. 1, a personal dialyzer 139 capable of preparing a dialysate may be connected to the circulation flow channel 110. The supply channel of the reverse osmosis water in the personal dialysis device 139 will be described later.
  • the first supply channel 131 connects the circulation channel 110 and the dialysis device 130 to each other.
  • the first supply flow path 131 is provided with the dialysate preparation device 160.
  • the reverse osmosis water flows through the first supply flow path 131 upstream of the dialysate preparation apparatus 160, and flows through the first supply flow path 131 downstream of the dialysate preparation apparatus 160. Dialysate flows through.
  • a discharge flow path 132 is connected to the dialysis machine 130. During dialysis, the dialysate used in the dialyzer 130 flows through the discharge flow path 132.
  • the personal dialysis device 139 is also connected to the discharge flow path 139y through which the used dialysate flows.
  • the dialysis machine cleaning system 100 includes a plurality of dialysis machines 130.
  • the dialyzer cleaning system 100 may include only one dialyzer 130.
  • the plurality of dialysis machines 130 are mutually connected to the first supply flow channel 131 via a plurality of branch flow channels 131x corresponding to the plurality of dialysis machines 130 on a one-to-one basis.
  • Each of the first supply flow channel 131 and the plurality of branch flow channels 131x is formed of a synthetic resin pipe.
  • the dialysate When performing dialysis, the dialysate is sequentially discharged through the first supply flow path 131 downstream of the dialysate preparation device 160, the branch flow path 131x, the dialyzer 130, and the discharge flow path 132.
  • the dialysis device 130 When the dialysis device 130 is operated for a long time, calcium carbonate adheres to the inner surfaces of these flow paths.
  • the electrolyzed water generator 140 takes in the reverse osmosis water flowing through the circulation flow channel 110 to generate electrolyzed water for cleaning.
  • the electrolyzed water generator 140 may be a two-tank type or a three-tank type.
  • the electrolyzed water generator is preferably a three-tank type in which sodium chloride is not mixed in the electrolyzed water generated by the electrolyzed water generator.
  • the reverse osmosis water is electrolyzed by adding a salt such as sodium chloride in the electrolyzed water generator 140.
  • the electrolyzed water generator 140 is of a three-tank type, the reverse osmosis water is electrolyzed in the electrolyzed water generator 140 while ions are supplied from an aqueous solution to which a salt such as sodium chloride is added.
  • the electrolyzed water generator 140 simultaneously generates acidic electrolyzed water and alkaline electrolyzed water by the electrolysis.
  • One of the acidic electrolyzed water and the alkaline electrolyzed water is used as the electrolyzed water for cleaning.
  • the acidic electrolyzed water is a hypochlorous acid aqueous solution.
  • the electrolyzed water generating apparatus 140 is configured to be switchable between a state of using acidic electrolyzed water as the electrolyzed water for cleaning and a state of using alkaline electrolyzed water as the electrolyzed water for cleaning.
  • the first bypass flow passage 141 connects the circulation flow passage 110 and the electrolyzed water generating device 140 to each other.
  • the electrolyzed water producing apparatus 140 produces acidic electrolyzed water and alkaline electrolyzed water by the above-mentioned electrolysis using the fluid flowing into the electrolyzed water producing apparatus 140 from the first bypass channel 141.
  • the second bypass flow path 142 connects the electrolyzed water generation device 140 and the first supply flow path 131 to each other. As a result, the electrolyzed water generation device 140 can supply the electrolyzed water for cleaning to the first supply flow path 131.
  • the electrolyzed water producing apparatus 140 sends one of the produced acidic electrolyzed water and alkaline electrolyzed water to the second bypass flow path 142 as electrolyzed water for cleaning.
  • the second bypass passage 142 is provided with a fifth opening / closing valve 150e.
  • the fifth on-off valve When the electrolyzed water producing apparatus 140 does not produce electrolyzed water, the fifth on-off valve is in the closed state. When the electrolyzed water producing apparatus 140 produces electrolyzed water, the fifth on-off valve is in an open state. As shown in FIG. 1, when performing dialysis, the fifth on-off valve is closed.
  • the first opening / closing valve 150a is provided in the circulation flow channel 110, downstream of the connection portion with the first bypass flow passage 141 and upstream of the connection portion with the first supply flow passage 131. As shown in FIG. 1, when performing dialysis, the first on-off valve 150a is open.
  • the second opening / closing valve 150b is provided in the first supply passage 131 between the connection portion with the circulation passage 110 and the connection portion with the second bypass passage 142. As shown in FIG. 1, when performing dialysis, the second on-off valve 150b is open.
  • the dialysate preparation device 160 is provided in the first supply flow path 131 closer to the dialyzer 130 than the connection part with the second bypass flow path 142.
  • the dialysate preparation device 160 When dialysis is performed, in the dialysate preparation device 160, the reverse osmosis water supplied from the upstream side of the first supply flow path 131 is mixed with the first stock solution and the second stock solution, so that the dialysis is performed. The liquid is prepared.
  • the first stock solution is, for example, a liquid preparation prepared by dissolving calcium salt, magnesium salt, potassium salt and sodium salt, glucose and the like in water.
  • the second stock solution is a liquid preparation prepared by dissolving sodium hydrogen carbonate or the like in water.
  • the first stock solution tank 170a is connected to the dialysate preparation apparatus 160 and supplies the first stock solution to the dialysate preparation apparatus 160.
  • the first stock solution tank 170a and the dialysate preparation device 160 are connected to each other via a first stock solution supply channel 172a.
  • the first stock solution is prepared by dissolving the powder formulation for the first stock solution in the reverse osmosis water in the first stock solution tank 170a.
  • the second stock solution tank 170b is connected to the dialysate preparation device 160 and supplies the second stock solution to the dialysate preparation device 160.
  • the second stock solution tank 170b and the dialysate preparation device 160 are connected to each other via a second stock solution supply channel 172b.
  • the second stock solution is prepared by dissolving the powder formulation for the second stock solution in the reverse osmosis water in the second stock solution tank 170b.
  • the second supply flow path 171 connects the circulation flow path 110 to each of the first stock solution tank 170a and the second stock solution tank 170b.
  • the second supply flow path 171 is branched on the downstream side into a first stock solution tank 170a side and a second stock solution tank 170b side.
  • the third bypass flow passage 143 connects the electrolyzed water generation device 140 and the second supply flow passage 171 to each other.
  • the third bypass flow passage 143 is configured to allow the same cleaning electrolysis water as the cleaning electrolysis water flowing through the second bypass flow passage 142 to flow.
  • the third on-off valve 150c is provided in the second supply passage 171 on the circulation passage 110 side with respect to the connection portion with each of the first stock solution tank 170a, the second stock solution tank 170b, and the third bypass path 143. ..
  • the third on-off valve 150c is open when dialysis is performed.
  • the reverse osmosis water flowing through the circulation channel 110 is supplied to each of the first stock solution tank 170a and the second stock solution tank 170b via the second supply channel 171.
  • each of the plurality of personal dialysis devices 139 is connected to each of the first stock solution tank 170 a, the second stock solution tank 170 b, and the third bypass flow path 143 in the second supply flow path 171. It is connected to the circulation flow channel 110 via a third supply flow channel 139x connected between the third on-off valve 150c and the connection portion located closest to the circulation flow channel 110 side. Therefore, the reverse osmosis water is supplied to each of the plurality of personal dialysis devices 139 in the same manner as the first stock solution tank 170a and the second stock solution tank 170b.
  • the electrolytic water for cleaning flows in the same manner as in the first stock solution tank 170a and the second stock solution tank 170b.
  • the number of the personal dialysis device 139 indirectly connected to the circulation flow channel 110 may be one, and may not necessarily be provided.
  • the fourth opening / closing valve 150d is provided in the third bypass passage 143. As shown in FIG. 1, when dialysis is performed, the fourth on-off valve 150d is closed. As a result, the reverse osmosis water is prevented from flowing into the electrolyzed water generating device 140 via the third bypass flow passage 143.
  • the dialysate preparation device 160, the first stock solution tank 170a, and the second stock solution tank 170b are connected to a discharge channel 163, a first stock solution discharge channel 173a, and a second stock solution discharge channel 173b, respectively. ..
  • the dialysate preparation device 160 is dialyzed.
  • the liquid is discharged to the discharge channel 163. It should be noted that the dialysate or the electrolyzed water for cleaning does not have to flow in the discharge channel 163 during the dialysis and the cleaning described later.
  • the first stock solution is discharged to the first stock solution discharge channel 173a. It should be noted that the dialysis solution or the electrolyzed water for cleaning need not flow in the first stock solution discharge flow channel 173a during dialysis and during cleaning as described below.
  • the second stock solution tank 170b If an abnormality occurs in the concentration of the second stock solution in the second stock solution tank 170b, or if the second stock solution is stored in the second stock solution tank 170b for a long time, the second stock solution tank 170b , The second stock solution is discharged to the second stock solution discharge channel 173b. Note that the dialysis solution or the electrolytic water for cleaning need not flow in the second stock solution discharge flow path 173b during the dialysis and the cleaning described below.
  • the neutralization pipe 180 is connected to the electrolyzed water producing apparatus 140, and electrolysis of one of the acidic electrolyzed water and the alkaline electrolyzed water produced in the electrolyzed water producing apparatus 140, which is not the electrolysis water for cleaning.
  • Electrolyzed water for neutralization is discharged as water. That is, when acidic electrolyzed water flows as the electrolyzed water for cleaning, alkaline electrolyzed water is discharged to the neutralization pipe 180 as electrolyzed water for neutralization. When alkaline electrolyzed water flows as the electrolyzed water for cleaning, acidic electrolyzed water is discharged to the neutralization pipe 180 as electrolyzed water for neutralization.
  • the dialysis machine cleaning system 100 further includes a neutralization tank 181.
  • the neutralization tank 181 is connected to the downstream side of each of the plurality of discharge flow paths 132.
  • the neutralization tank 181 is connected to the downstream side of each of the plurality of discharge channels 139y.
  • the neutralization tank 181 is connected to the downstream side of the neutralization pipe 180. That is, the electrolysis water for cleaning and the electrolysis water for neutralization each flow into the neutralization tank 181. In this way, the neutralization pipe 180 is configured such that the neutralized electrolyzed water discharged from the neutralization pipe 180 joins with the cleaning electrolyzed water discharged from the dialyzer 130.
  • the neutralization tank 181 does not necessarily have to be provided.
  • the electrolyzed water for neutralization is alkaline electrolyzed water.
  • the electrolyzed water for neutralization is acidic electrolyzed water. Therefore, in the neutralization tank 181, whether the electrolytic water for cleaning is acidic electrolytic water or alkaline electrolytic water is neutralized by the electrolytic water for neutralization. The electrolytic water for cleaning is neutralized in the neutralization tank 181, and then discharged from the neutralization tank 181.
  • downstream side of the discharge flow channel 163 is also connected to the neutralization tank 181.
  • the dialysate in the dialysate preparation device 160 is discharged, the dialysate passes through the discharge channel 163 and flows into the neutralization tank 181.
  • the dialysate preparation device 160 may be washed with the above-mentioned electrolyzed water for washing after the dialysate preparation device 160 is drained.
  • the electrolytic water for cleaning is discharged by flowing the electrolytic water for cleaning used for cleaning into the neutralization tank 181 through the discharge channel 163.
  • the downstream side of the first stock solution discharge flow path 173a is also connected to the neutralization tank 181.
  • the first stock solution in the first stock solution tank 170a is discharged, the first stock solution passes through the first stock solution discharge flow path 173a and flows into the neutralization tank 181.
  • the first stock solution tank 170a may be washed with the above-mentioned electrolytic water for cleaning after the first stock solution in the first stock solution tank 170a is discharged.
  • the electrolytic water for cleaning is discharged by flowing the electrolytic water for cleaning used for cleaning into the neutralization tank 181 through the first stock solution discharge flow path 173a.
  • the downstream side of the second stock solution discharge flow path 173b is also connected to the neutralization tank 181.
  • the second undiluted solution in the second undiluted solution tank 170b is discharged, the second undiluted solution passes through the second undiluted solution discharge passage 173b and flows into the neutralization tank 181.
  • the second stock solution tank 170b may be washed with the above-described electrolytic water for cleaning after the second stock solution in the second stock solution tank 170b is discharged.
  • the electrolytic water for cleaning is discharged by flowing the electrolytic water for cleaning used for cleaning into the neutralization tank 181 through the second stock solution discharge channel 173b.
  • the operation of cleaning each component in the dialysis machine cleaning system 100 will be described below.
  • the operation of cleaning the personal dialysis device 139 is the same as that of each of the first stock solution tank 170a and the second stock solution tank 170b, and thus the description thereof is omitted.
  • FIG. 2 is a circuit diagram showing a state in which the tank in the reverse osmosis water generator is being washed in the dialysis machine washing system according to the embodiment of the present invention.
  • the first on-off valve 150a is in the closed state and the second on-off valve 150b is in the open state. Has become.
  • the electrolyzed water generator 140 When cleaning the tank in the reverse osmosis water generator 120, the electrolyzed water generator 140 causes acidic electrolyzed water to flow into the second bypass flow path 142 as electrolyzed water for cleaning.
  • the pH value of the acidic electrolyzed water is, for example, 3, and the hypochlorous acid concentration in the acidic electrolyzed water is about 50 ppm.
  • the acidic electrolyzed water produced by the electrolyzed water producing apparatus 140 flows from the second bypass passage 142 to the first supply passage 131.
  • the acidic electrolyzed water that has flowed into the first supply flow path 131 flows into the circulation flow path 110.
  • the acidic electrolyzed water that has flowed into the circulation flow channel 110 from the first supply flow channel 131 flows to the reverse osmosis water generation device 120.
  • the acidic electrolyzed water is mixed with the reverse osmosis water generated by the reverse osmosis water generator 120 and diluted.
  • acidic electrolyzed water having a hypochlorous acid concentration of about 1 ppm is produced by the reverse osmosis water production apparatus 120.
  • the acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into the circulation flow channel 110 again from the reverse osmosis water generator 120.
  • the acidic electrolyzed water that has circulated in the circulation flow channel 110 flows into the electrolyzed water generation device 140 from the circulation flow channel 110.
  • the electrolyzed water producing apparatus 140 uses the diluted acidic electrolyzed water instead of the reverse osmosis water to perform the electrolysis described above, and produces the acidic electrolyzed water having a hypochlorous acid concentration of about 50 ppm.
  • the hypochlorous acid concentration About 50 ppm of acidic electrolyzed water flows through.
  • the acidic electrolyzed water having a hypochlorous acid concentration of about 1 ppm flows.
  • the dialyzer cleaning system 100 when cleaning the tank in the reverse osmosis water generator 120, the tank in the reverse osmosis water generator 120 is cleaned and sterilized with the acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm.
  • the third opening / closing valve 150c is in the open state and the fourth opening / closing valve 150d is in the closed state. Therefore, when cleaning the tank in the reverse osmosis water generation apparatus 120, the acidic electrolyzed water as the electrolyzed water for cleaning does not flow into the third bypass flow passage 143. As a result, the flow path through which the electrolyzed water generator 140 directly supplies the acidic electrolyzed water is only the second bypass flow path 142.
  • the dialyzer cleaning system 100 when cleaning the tank in the reverse osmosis water generator 120, acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm is removed from the tank in the reverse osmosis water generator 120. Some have been discharged. As a result, the flow rate of the acidic electrolyzed water flowing through the circulation channel 110 is maintained at the threshold value. Therefore, when cleaning the tank in the reverse osmosis water generator 120, the acidic electrolyzed water does not flow into each of the dialysate preparation device 160, the first stock solution tank 170a, and the second stock solution tank 170b.
  • the dialyzer cleaning system 100 performs acidic electrolysis on each of the dialysate preparation device 160, the first stock solution tank 170a, and the second stock solution tank 170b. It is designed to allow water to flow.
  • the dialyzer cleaning system 100 is preferably configured so that the acidic electrolyzed water discharged from the tank in the reverse osmosis water generator 120 joins with the alkaline electrolyzed water flowing through the neutralization pipe 180.
  • the acidic electrolyzed water does not necessarily have to be discharged from the tank in the reverse osmosis water generator 120.
  • the excess amount of the acidic electrolyzed water flowing through the circulation channel 110 that exceeds the threshold value is adjusted from the circulation channel 110 through the first bypass channel 141, the second bypass channel 142, and the first supply channel 131 to prepare the dialysate.
  • Flow into device 160 the excess amount of the acidic electrolyzed water that has flowed into the first stock solution tank 170a from the circulation flow path 110 through the second supply path 171 flows into the dialysate preparation device 160 through the first stock solution supply path 172a.
  • the excess amount of the acidic electrolyzed water that has flowed from the circulation flow path 110 into the second stock solution tank 170b through the second supply path 171 flows into the dialysate preparation device 160 through the second stock solution supply path 172b.
  • the process of weak acid cleaning with acidic electrolyzed water with a hypochlorous acid concentration of 1 ppm will be described.
  • the state of each on-off valve is the same as the state shown in FIG.
  • the electrolyzed water producing apparatus 140 does not produce each of the acidic electrolyzed water and the alkaline electrolyzed water.
  • the reverse osmosis water generation device 120 When performing weak acid cleaning, the reverse osmosis water generation device 120 causes the generated reverse osmosis water to flow into the circulation flow channel 110. As a result, the acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into each flow path from the circulation flow path 110.
  • acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into the dialysate preparation device 160 from the circulation flow path 110 through the first supply flow path 131.
  • acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into the dialysate preparation device 160 from the circulation channel 110 through the second supply channel 171, the first stock solution tank 170a, and the first stock solution supply channel 172a.
  • the acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into the dialysate preparation device 160 from the circulation channel 110 through the second supply channel 171, the second stock solution tank 170b, and the second stock solution supply channel 172b. ..
  • the acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm that has flowed into the dialysate preparation device 160 has a first supply flow path 131, a plurality of dialysis machines 130, a plurality of branch flow paths 131x, a plurality of discharge flow paths 132, and The neutralization tank 181 sequentially flows and is discharged.
  • FIG. 3 is a circuit diagram showing a state in which strong acid cleaning is performed in the dialysis machine cleaning system according to the embodiment of the present invention.
  • the first opening / closing valve 150a is open, the second opening / closing valve 150b is closed, the third opening / closing valve 150c is closed, and the fourth opening / closing is performed.
  • the valve 150d is open and the fifth on-off valve 150e is open.
  • the electrolyzed water generating apparatus 140 When performing strong acid cleaning, the electrolyzed water generating apparatus 140 generates acidic electrolyzed water as electrolyzed water for cleaning, as in the case of performing dialysis.
  • the acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm produced by the electrolyzed water producing device 140 flows into the first supply passage 131 from the second bypass passage 142. Since the second opening / closing valve 150b is in the open state, the acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm that has flowed into the first supply flow path 131 flows into the dialysate preparation device 160 through the first supply flow path 131. To do.
  • the acidic electrolyzed water having a hypochlorous acid concentration of 50 ppm that has flowed into the dialysate preparation device 160 has a first supply flow path 131, a plurality of dialysis machines 130, a plurality of branch flow paths 131x, a plurality of discharge flow paths 132, and The neutralization tank 181 sequentially flows and is discharged.
  • the circulation channel 110 acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm or less is circulated, and the hypochlorous acid concentration decreases over time.
  • the acidic electrolyzed water having a hypochlorous acid concentration of 50 ppm flows through the dialysate preparation device 160 and the dialyzer 130 without flowing into the circulation flow channel 110. ..
  • each of the dialyzer 130 and the dialysate preparation device 160 can be washed with acidic electrolyzed water having a hypochlorous acid concentration of 50 ppm.
  • the electrolyzed water generator 140 when performing strong acid cleaning, also supplies the electrolyzed electrolyzed water having a hypochlorous acid concentration of 50 ppm to the third bypass passage 143. Since the third on-off valve 150c is in the closed state, the acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm that has flowed into the third bypass flow passage 143 is discharged through the second supply flow passage 171 to the first stock solution tank 170a and the It flows into each of the two stock solution tanks 170b.
  • the acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm that has flowed into the first stock solution tank 170a flows into the dialysate preparation device 160 through the first stock solution supply channel 172a.
  • acidic electrolyzed water with a hypochlorous acid concentration of 50 ppm is passed through the first stock solution tank 170a and the second stock solution tank 170b without flowing into the circulation flow channel 110. Shed.
  • each of the first stock solution tank 170a and the second stock solution tank 170b can be washed with acidic electrolyzed water having a hypochlorous acid concentration of 50 ppm.
  • the electrolyzed water generator 140 supplies alkaline electrolyzed water to the neutralization pipe 180.
  • the pH value of alkaline electrolyzed water is approximately 11.
  • the alkaline electrolyzed water that has flowed through the neutralization pipe 180 is neutralized with the acidic electrolyzed water that has flowed through the discharge flow path 132 in the neutralization tank 181, and then discharged.
  • the electrolyzed water generation device 140 When performing alkaline cleaning, the electrolyzed water generation device 140 generates alkaline electrolyzed water as cleaning electrolyzed water.
  • the electrolyzed water producing device 140 produces acidic electrolyzed water as the electrolyzed water for neutralization. That is, when performing alkaline cleaning, the acidic electrolyzed water flowing in the second bypass flow path 142 is switched to alkaline electrolyzed water, and the alkaline electrolyzed water flowing in the neutralization pipe 180 is switched to acidic electrolyzed water.
  • the pH value of alkaline electrolyzed water is approximately 11.
  • the alkaline electrolyzed water flows through the dialysate preparation device 160, the dialysis device 130, the first stock solution tank 170a, and the second stock solution tank 170b without flowing into the circulation channel 110. ..
  • each of the dialysate preparation device 160, the dialyzer 130, the first stock solution tank 170a, and the second stock solution tank 170b can be washed with alkaline electrolyzed water.
  • the calcium carbonate adhering to the dialysate circuit of the dialyzer 130 is removed by acidic electrolyzed water by cleaning with acidic electrolyzed water and then alkaline electrolyzed water. Then, each of the protein component and the silicon-containing component can be removed with alkaline electrolyzed water. As a result, the deposits in the dialysate circuit of the dialyzer 130 can be effectively removed.
  • the electrolyzed water producing apparatus 140 When electrolyzing with water, the electrolyzed water producing apparatus 140 does not produce acidic electrolyzed water or alkaline electrolyzed water.
  • the reverse osmosis water generation apparatus 120 When washing with water, the reverse osmosis water generation apparatus 120 causes the generated reverse osmosis water to flow into the circulation channel 110.
  • Reverse osmosis water flowing through the circulation flow channel 110 flows into the dialysate preparation device 160 from the circulation flow channel 110 through the first supply flow channel 131.
  • the reverse osmosis water that has flowed from the circulation channel 110 into the first stock solution tank 170a through the second supply channel 171 flows into the dialysate preparation apparatus 160 through the first stock solution supply channel 172a.
  • the reverse osmosis water that has flowed from the circulation channel 110 into the second stock solution tank 170b through the second supply channel 171 flows into the dialysate preparation device 160 through the second stock solution supply channel 172b.
  • the reverse osmosis water that has flowed into the dialysate preparation device 160 sequentially flows through the first supply flow path 131, the plurality of dialysis machines 130, the plurality of branch flow paths 131x, the plurality of discharge flow paths 132, and the neutralization tank 181. Is discharged.
  • the dialysate preparation device 160 can be cleaned without cleaning the dialysate circuit of the dialyzer 130.
  • the liquid such as the electrolytic water for cleaning flowing through the first supply flow path 131 is controlled so as to pass through the discharge flow path 163 and flow into the neutralization tank 181.
  • the first stock solution tank 170a can be cleaned without cleaning the dialysate circuit of the dialyzer 130 and the dialysate preparation device 160.
  • the liquid such as the electrolyzed water for cleaning flowing through the first stock solution supply flow path 172a is controlled to pass through the first stock solution discharge flow path 173a and flow into the neutralization tank 181. ..
  • the second stock solution tank 170b can be cleaned without cleaning the dialysate circuit of the dialyzer 130 and the dialysate preparation device 160.
  • the liquid such as the electrolyzed water for cleaning flowing through the second stock solution supply flow path 172b is controlled so as to pass through the second stock solution discharge flow path 173b and flow into the neutralization tank 181. ..
  • FIG. 4 is a circuit diagram showing a state in which hot water washing is performed in the dialysis machine washing system according to the embodiment of the present invention.
  • the first opening / closing valve 150a is open, the second opening / closing valve 150b is closed, the third opening / closing valve 150c is closed, and the fourth opening / closing valve 150c is closed.
  • the on-off valve 150d is closed.
  • the reverse osmosis water flowing through the circulation flow channel 110 is heated by the heater provided in the reverse osmosis water generator 120.
  • the heated reverse osmosis water circulates in the circulation flow channel 110, so that the circulation flow channel 110 is sterilized.
  • the first bypass flow channel 141 connects the circulation flow channel 110 and the electrolyzed water generating device 140 to each other.
  • the second bypass flow passage 142 connects the electrolyzed water generation device 140 and the first supply flow passage 131 to each other.
  • the first opening / closing valve 150a is provided in the circulation flow channel 110, downstream of the connection portion with the first bypass flow passage 141 and upstream of the connection portion with the first supply flow passage 131.
  • the second opening / closing valve 150b is provided in the first supply passage 131 between the connection portion with the circulation passage 110 and the connection portion with the second bypass passage 142.
  • the dialysate preparation apparatus 160 is provided in the first supply flow path 131 on the dialysis machine 130 side with respect to the connection portion with the second bypass flow path 142.
  • the third bypass flow passage 143 connects the electrolyzed water generation device 140 and the second supply flow passage 171 to each other.
  • the third on-off valve 150c is provided in the second supply passage 171 on the circulation passage 110 side of the connection portion with each of the first stock solution tank 170a, the second stock solution tank 170b, and the third bypass path 143. ..
  • the fourth opening / closing valve 150d is provided in the third bypass passage 143.
  • the acidic electrolyzed water having a lower concentration of hypochlorous acid than the acidic electrolyzed water for cleaning the dialyzer 130 can be used. It becomes possible to wash the circulation channel of the reverse osmosis water.
  • the neutralization pipe 180 is configured such that the neutralized electrolyzed water discharged from the neutralization pipe 180 is the cleaning electrolyzed water discharged from the dialysis device 130. It is configured to meet. This eliminates the need for a neutralizing agent for neutralizing the electrolyzed water used for cleaning and eliminating the need for a tank for storing the neutralizing agent, thus saving space in the dialysis machine cleaning system 100.
  • 100 dialysis machine cleaning system 110 circulation flow path, 120 reverse osmosis water generator, 121 raw water supply unit, 130 dialysis machine, 131 first supply flow path, 131x branch flow path, 132 discharge flow path, 139 personal dialysis machine 139x third supply passage, 139y discharge passage, 140 electrolyzed water generator, 141 first bypass passage, 142 second bypass passage, 143 third bypass passage, 150a first opening / closing valve, 150b second opening / closing Valve, 150c third opening / closing valve, 150d fourth opening / closing valve, 150e fifth opening / closing valve, 160 dialysate preparation device, 163 discharge flow path, 170a first stock solution tank, 170b second stock solution tank, 171, second supply path, 172a 1st undiluted solution supply flow path, 172b 2nd undiluted solution supply flow path, 173a 1st undiluted solution discharge flow path, 173b 2nd undiluted solution discharge flow path, 180 neutralization piping, 181 neutralization tank.

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Abstract

In this invention, a circulation flow path (110) causes reverse osmosis water to circulate in one direction. The reverse osmosis water generation device (120) is capable of supplying the reverse osmosis water to the circulation flow path (110). A dialysis device (130) is connected directly or indirectly to the circulation flow path (110). An electrolysis water generation device (140) takes in the reverse osmosis water flowing through the circulation flow path (110) to generate cleaning electrolysis water and can supply the cleaning electrolysis water to a first supply flow path (131). A first opening-closing valve (150a) is provided in the circulation flow path (110), more on the downstream side than a part connected to a first bypass flow path (141) and more on the upstream side than a part connected to the first supply flow path (131). A second opening-closing valve (150b) is provided in the first supply flow path (131), between a part connected to the circulation flow path (110) and a part connected to a second bypass flow path (142).

Description

透析装置洗浄システムDialysis machine cleaning system
　本発明は、透析装置洗浄システムに関する。 The present invention relates to a dialysis machine cleaning system.
　透析装置洗浄システムの構成を開示した先行文献として、特開平７－２８４７４４号公報(特許文献１)がある。特許文献１に記載された透析装置洗浄システムにおいては、酸性電解水の流出路とアルカリ性電解水の流出路は、逆浸透水タンクからの逆浸透水の流出路とともに四方弁に接続されている。四方弁によって選択された流体はポンプによって中央供給装置に供給され、さらにこの中央供給装置から透析用監視装置に送られる。 As a prior document disclosing the configuration of a dialysis machine cleaning system, there is JP-A-7-284744 (Patent Document 1). In the dialysis machine cleaning system described in Patent Document 1, the outflow passage of the acidic electrolyzed water and the outflow passage of the alkaline electrolyzed water are connected to the four-way valve together with the outflow passage of the reverse osmosis water from the reverse osmosis water tank. The fluid selected by the four-way valve is supplied by a pump to a central feeder, which then feeds a dialysis monitor.
特開平７－２８４７４４号公報Japanese Patent Laid-Open No. 7-284744
　従来の透析装置洗浄システムにおいて、透析装置の洗浄を行なう場合は、アルカリ性電解水、逆浸透水および酸性電解水が中央供給装置に順次送られる。酸性電解水は、次亜塩素酸水溶液である。 In the conventional dialysis machine cleaning system, when cleaning the dialysis machine, alkaline electrolyzed water, reverse osmosis water, and acid electrolyzed water are sequentially sent to the central supply unit. The acidic electrolyzed water is a hypochlorous acid aqueous solution.
　透析装置洗浄システムにおいては、逆浸透水の循環流路を含む場合がある。逆浸透水は塩素を含まないため、循環流路における菌の繁殖を抑制するために循環流路の洗浄が必要になる。循環流路は、透析液流路と異なり、蛋白成分の物質などは流れないため、酸性度の高い酸性電解水で洗浄する必要はない。透析装置の洗浄と同様に、酸性度の高い酸性電解水、すなわち、濃度の高い次亜塩素酸水溶液によって循環流路の洗浄を行なった場合、循環流路が劣化する。 The dialyzer cleaning system may include a reverse osmosis water circulation channel. Since reverse osmosis water does not contain chlorine, it is necessary to clean the circulation channel in order to suppress the growth of bacteria in the circulation channel. Unlike the dialysate flow channel, the circulation flow channel does not flow a substance such as a protein component, so that it is not necessary to wash with acidic electrolyzed water having a high acidity. As in the case of cleaning the dialysis device, when the circulation flow passage is washed with acidic electrolyzed water having a high acidity, that is, a high concentration aqueous solution of hypochlorous acid, the circulation flow passage deteriorates.
　本発明は上記の問題点に鑑みてなされたものであって、透析装置を洗浄する酸性電解水より次亜塩素酸の濃度が低い酸性電解水によって逆浸透水の循環流路を洗浄可能である、透析装置洗浄システムを提供することを目的とする。 The present invention has been made in view of the above problems, and it is possible to wash the circulation flow path of reverse osmosis water with acidic electrolyzed water having a lower concentration of hypochlorous acid than acidic electrolyzed water for washing a dialysis machine. , A dialyzer cleaning system is provided.
　本発明に基づく透析装置洗浄システムは、循環流路と、逆浸透水生成装置と、透析装置と、第１供給流路と、電解水生成装置と、第１バイパス流路と、第２バイパス流路と、第１開閉弁と、第２開閉弁とを備えている。循環流路は、逆浸透水を一方向に循環させる。逆浸透水生成装置は、循環流路に設けられ、循環流路に逆浸透水を供給可能である。透析装置は、循環流路に直接的または間接的に接続されている。第１供給流路は、循環流路と透析装置とを互いに接続する。電解水生成装置は、循環流路を流れる逆浸透水を取り込んで洗浄用電解水を生成し、かつ、洗浄用電解水を第１供給流路に供給可能である。第１バイパス流路は、循環流路と電解水生成装置とを互いに接続する。第２バイパス流路は、電解水生成装置と第１供給流路とを互いに接続する。第１開閉弁は、循環流路において、第１バイパス流路との接続部より下流側であって、第１供給流路との接続部より上流側に設けられている。第２開閉弁は、第１供給流路において、循環流路との接続部、および、第２バイパス流路との接続部、の間に設けられている。 A dialysis machine cleaning system based on the present invention includes a circulation flow path, a reverse osmosis water generation apparatus, a dialysis machine, a first supply flow path, an electrolyzed water generation apparatus, a first bypass flow path, and a second bypass flow path. A passage, a first opening / closing valve, and a second opening / closing valve. The circulation channel circulates the reverse osmosis water in one direction. The reverse osmosis water generation device is provided in the circulation flow channel and can supply the reverse osmosis water to the circulation flow channel. The dialyzer is directly or indirectly connected to the circulation channel. The first supply channel connects the circulation channel and the dialysis device to each other. The electrolyzed water generation device can take in the reverse osmosis water flowing through the circulation flow path to generate the electrolysis water for cleaning, and can supply the electrolysis water for cleaning to the first supply flow path. The first bypass flow path connects the circulation flow path and the electrolyzed water generating device to each other. The second bypass flow passage connects the electrolyzed water generating device and the first supply flow passage to each other. The first on-off valve is provided in the circulation flow path, downstream of the connection with the first bypass flow path and upstream of the connection with the first supply flow path. The second opening / closing valve is provided in the first supply passage between the connection portion with the circulation passage and the connection portion with the second bypass passage.
　本発明の一形態においては、透析装置洗浄システムは、透析液調製装置と、第１原液タンクと、第２原液タンクと、第２供給流路と、第３バイパス流路と、第３開閉弁と、第４開閉弁とをさらに備えている。透析液調製装置は、第１供給流路において、第２バイパス流路との接続部より透析装置側に設けられている。第１原液タンクは、透析液調製装置に接続され、透析液調製装置に第１原液を供給する。第２原液タンクは、透析液調製装置に接続され、透析液調製装置に第２原液を供給する。第２供給流路は、循環流路と、第１原液タンクおよび第２原液タンクの各々とを互いに接続する。第３バイパス流路は、電解水生成装置と第２供給流路とを互いに接続する。第３開閉弁は、第２供給流路において、第１原液タンク、第２原液タンクおよび第３バイパス流路の各々との接続部より循環流路側に設けられている。第４開閉弁は、第３バイパス流路に設けられている。 In one aspect of the present invention, a dialyzer cleaning system includes a dialysate preparation device, a first stock solution tank, a second stock solution tank, a second supply passage, a third bypass passage, and a third opening / closing valve. And a fourth opening / closing valve. The dialysate preparation device is provided in the first supply channel on the dialyzer side with respect to the connection portion with the second bypass channel. The first stock solution tank is connected to the dialysate preparation apparatus and supplies the first stock solution to the dialysate preparation apparatus. The second stock solution tank is connected to the dialysate preparation apparatus and supplies the second stock solution to the dialysate preparation apparatus. The second supply flow path connects the circulation flow path to each of the first stock solution tank and the second stock solution tank. The third bypass flow passage connects the electrolyzed water generation device and the second supply flow passage to each other. The third opening / closing valve is provided in the second supply passage on the circulation passage side from the connection portion with each of the first stock solution tank, the second stock solution tank, and the third bypass flow path. The fourth opening / closing valve is provided in the third bypass passage.
　本発明の一形態においては、透析装置洗浄システムは、中和用配管をさらに備えている。中和用配管は、電解水生成装置に接続され、電解水生成装置において生成された酸性電解水およびアルカリ性電解水のうち洗浄用電解水ではない方の中和用電解水を排出する。中和用配管は、中和用配管から排出された中和用電解水が、透析装置から排出された洗浄用電解水と合流するように構成されている。 In one aspect of the present invention, the dialysis machine cleaning system further includes a neutralization pipe. The neutralization pipe is connected to the electrolyzed water generating device and discharges the electrolyzed neutralizing water that is not the electrolyzed water for cleaning out of the acidic electrolyzed water and the alkaline electrolyzed water generated in the electrolyzed water generator. The neutralizing pipe is configured such that the neutralizing electrolytic water discharged from the neutralizing pipe joins with the cleaning electrolytic water discharged from the dialyzer.
　本発明によれば、透析装置を洗浄する酸性電解水より次亜塩素酸の濃度が低い酸性電解水によって逆浸透水の循環流路を洗浄可能である。 According to the present invention, the circulation passage of reverse osmosis water can be washed with acidic electrolyzed water having a lower concentration of hypochlorous acid than the acidic electrolyzed water for washing the dialysis machine.
本発明の一実施形態に係る透析装置洗浄システムにおいて、透析を実施している状態を示す回路図である。It is a circuit diagram which shows the state which is performing the dialysis in the dialysis machine cleaning system which concerns on one Embodiment of this invention. 本発明の一実施形態に係る透析装置洗浄システムにおいて、逆浸透水生成装置内のタンクを洗浄している状態を示す回路図である。FIG. 4 is a circuit diagram showing a state in which the tank in the reverse osmosis water generator is being washed in the dialysis machine washing system according to the embodiment of the present invention. 本発明の一実施形態に係る透析装置洗浄システムにおいて、強酸洗浄している状態を示す回路図である。It is a circuit diagram which shows the state which is performing strong acid washing in the dialysis machine washing system which concerns on one Embodiment of this invention. 本発明の一実施形態に係る透析装置洗浄システムにおいて、熱水洗浄している状態を示す回路図である。It is a circuit diagram which shows the state which is hot water washing | cleaning in the dialysis machine washing | cleaning system which concerns on one Embodiment of this invention.
　以下、本発明の一実施形態に係る透析装置洗浄システムについて図面を参照して説明する。以下の実施形態の説明においては、図中の同一または相当部分には同一符号を付して、その説明は繰り返さない。 Hereinafter, a dialysis machine cleaning system according to an embodiment of the present invention will be described with reference to the drawings. In the following description of the embodiments, the same or corresponding parts in the drawings will be denoted by the same reference numerals and the description thereof will not be repeated.
　図１は、本発明の一実施形態に係る透析装置洗浄システムにおいて、透析を実施している状態を示す回路図である。以下、透析を実施している状態における流体の流れる方向の上流側および下流側を、それぞれ、単に「上流側」および「下流側」という場合がある。 FIG. 1 is a circuit diagram showing a state in which dialysis is being performed in the dialysis machine cleaning system according to the embodiment of the present invention. Hereinafter, the upstream side and the downstream side in the fluid flow direction in the state of performing dialysis may be simply referred to as “upstream side” and “downstream side”, respectively.
　図１に示すように、本発明の一実施形態に係る透析装置洗浄システム１００は、循環流路１１０と、逆浸透水生成装置１２０と、透析装置１３０と、第１供給流路１３１と、電解水生成装置１４０と、第１バイパス流路１４１と、第２バイパス流路１４２と、第１開閉弁１５０ａと、第２開閉弁１５０ｂと、透析液調製装置１６０と、第１原液タンク１７０ａと、第２原液タンク１７０ｂと、第２供給流路１７１と、第３バイパス流路１４３と、第３開閉弁１５０ｃと、第４開閉弁１５０ｄと、中和用配管１８０とを備えている。なお、中和用配管１８０は、必ずしも設けられていなくてもよい。 As shown in FIG. 1, a dialysis device cleaning system 100 according to an embodiment of the present invention includes a circulation flow channel 110, a reverse osmosis water generation device 120, a dialysis device 130, a first supply flow channel 131, and an electrolysis. A water generator 140, a first bypass passage 141, a second bypass passage 142, a first opening / closing valve 150a, a second opening / closing valve 150b, a dialysate preparation device 160, a first stock solution tank 170a, The second stock solution tank 170b, the second supply passage 171, the third bypass passage 143, the third opening / closing valve 150c, the fourth opening / closing valve 150d, and the neutralization pipe 180 are provided. The neutralization pipe 180 does not necessarily have to be provided.
　循環流路１１０は、逆浸透水を一方向に循環させる。本実施形態においては、循環流路１１０を循環する逆浸透水が、透析液の原料として用いられる。 The circulation channel 110 circulates reverse osmosis water in one direction. In this embodiment, the reverse osmosis water circulating in the circulation channel 110 is used as a raw material for the dialysate.
　循環流路１１０は、主にステンレス鋼で構成されている。仮に、透析装置１３０の洗浄時において、次亜塩素酸の濃度の高い酸性電解水を循環流路１１０で循環させた場合には、循環流路１１０のうちステンレス鋼で構成されている部分が次亜塩素酸の濃度の高い酸性電解水に長時間晒されることにより腐食して経時的に劣化する。 The circulation channel 110 is mainly made of stainless steel. If acidic electrolyzed water having a high concentration of hypochlorous acid is circulated through the circulation passage 110 during the cleaning of the dialysis device 130, the portion of the circulation passage 110 made of stainless steel is When it is exposed to acidic electrolyzed water having a high concentration of chlorous acid for a long time, it corrodes and deteriorates over time.
　逆浸透水生成装置１２０は、循環流路１１０に設けられている。本実施形態において、逆浸透水生成装置１２０は、逆浸透水が循環流路１１０を１周する際に逆浸透水生成装置１２０を２回通過するように構成されている。逆浸透水生成装置１２０は、内部に循環流路１１０と接続されたタンクを有している。 The reverse osmosis water generation device 120 is provided in the circulation flow channel 110. In the present embodiment, the reverse osmosis water generation apparatus 120 is configured to pass through the reverse osmosis water generation apparatus 120 twice when the reverse osmosis water makes one round in the circulation flow channel 110. The reverse osmosis water generation apparatus 120 has a tank internally connected to the circulation flow channel 110.
　逆浸透水生成装置１２０には、原料水供給部１２１が接続されている。逆浸透水生成装置１２０は、原料水供給部１２１から供給された原料水の一部を逆浸透膜に透過させることにより、逆浸透水を生成する。逆浸透水生成装置１２０は、生成した逆浸透水を循環流路１１０に供給可能である。原料水は、水道水であってもよく、浄水であってもよい。 A raw water supply unit 121 is connected to the reverse osmosis water generator 120. The reverse osmosis water generation device 120 generates reverse osmosis water by allowing a part of the raw water supplied from the raw water supply unit 121 to pass through the reverse osmosis membrane. The reverse osmosis water generation device 120 can supply the generated reverse osmosis water to the circulation channel 110. The raw material water may be tap water or purified water.
　本実施形態において、逆浸透水生成装置１２０は、ヒータを有している。逆浸透水生成装置１２０は、当該ヒータによって、循環流路１１０を流れる逆浸透水を加熱することができる。逆浸透水を加熱することにより、当該逆浸透水を原料として調製された透析液を、体温に近い温度にすることができる。なお、逆浸透水生成装置１２０は、ヒーターを有していなくてもよい。 In the present embodiment, the reverse osmosis water generation device 120 has a heater. The reverse osmosis water generation apparatus 120 can heat the reverse osmosis water flowing through the circulation channel 110 by the heater. By heating the reverse osmosis water, the dialysate prepared using the reverse osmosis water as a raw material can be brought to a temperature close to the body temperature. The reverse osmosis water generator 120 may not have a heater.
　透析装置１３０は、循環流路１１０に直接的または間接的に接続されている。本実施形態において、透析装置１３０は、循環流路１１０に間接的に接続されている。透析装置１３０には、循環流路１１０を流れる逆浸透水を用いて調製された透析液が供給される。 The dialysis device 130 is directly or indirectly connected to the circulation channel 110. In the present embodiment, the dialysis device 130 is indirectly connected to the circulation flow channel 110. The dialyser 130 is supplied with a dialysate prepared using reverse osmosis water flowing through the circulation channel 110.
　なお、透析装置１３０が、透析液を調製することができるように構成されている場合、透析装置１３０は、循環流路１１０に直接的に接続されていてもよい。また、図１に示すように、透析液を調製可能な個人用透析装置１３９が循環流路１１０に接続されていてもよい。個人用透析装置１３９における逆浸透水の供給流路については、後述する。 When the dialyzer 130 is configured to be able to prepare a dialysate, the dialyzer 130 may be directly connected to the circulation flow channel 110. Further, as shown in FIG. 1, a personal dialyzer 139 capable of preparing a dialysate may be connected to the circulation flow channel 110. The supply channel of the reverse osmosis water in the personal dialysis device 139 will be described later.
　第１供給流路１３１は、循環流路１１０と透析装置１３０とを互いに接続する。本実施形態において、第１供給流路１３１には、透析液調製装置１６０が設けられている。 The first supply channel 131 connects the circulation channel 110 and the dialysis device 130 to each other. In the present embodiment, the first supply flow path 131 is provided with the dialysate preparation device 160.
　すなわち、透析を実施する際には、第１供給流路１３１の透析液調製装置１６０より上流側においては逆浸透水が通流し、第１供給流路１３１の透析液調製装置１６０より下流側においては透析液が通流する。 That is, when performing dialysis, the reverse osmosis water flows through the first supply flow path 131 upstream of the dialysate preparation apparatus 160, and flows through the first supply flow path 131 downstream of the dialysate preparation apparatus 160. Dialysate flows through.
　透析装置１３０には、排出流路１３２が接続されている。透析実施時において、排出流路１３２には、透析装置１３０で使用された透析液が通流する。なお、個人用透析装置１３９にも、使用された透析液が通流する排出流路１３９ｙが接続されている。 A discharge flow path 132 is connected to the dialysis machine 130. During dialysis, the dialysate used in the dialyzer 130 flows through the discharge flow path 132. The personal dialysis device 139 is also connected to the discharge flow path 139y through which the used dialysate flows.
　本実施形態においては、透析装置洗浄システム１００が、複数の透析装置１３０を備えている。ただし、透析装置洗浄システム１００は、１つの透析装置１３０のみを備えていてもよい。 In the present embodiment, the dialysis machine cleaning system 100 includes a plurality of dialysis machines 130. However, the dialyzer cleaning system 100 may include only one dialyzer 130.
　複数の透析装置１３０は、複数の透析装置１３０と１対１で対応する複数の分岐流路１３１ｘを介して、第１供給流路１３１と互いに接続されている。第１供給流路１３１および複数の分岐流路１３１ｘの各々は、合成樹脂製の配管で構成されている。 The plurality of dialysis machines 130 are mutually connected to the first supply flow channel 131 via a plurality of branch flow channels 131x corresponding to the plurality of dialysis machines 130 on a one-to-one basis. Each of the first supply flow channel 131 and the plurality of branch flow channels 131x is formed of a synthetic resin pipe.
　透析を実施する際は、透析液は、第１供給流路１３１の透析液調製装置１６０より下流側、分岐流路１３１ｘ、透析装置１３０および排出流路１３２を順次通流して、排出される。透析装置１３０を長時間稼働させると、これらの流路の内面に、炭酸カルシウムが付着する。 When performing dialysis, the dialysate is sequentially discharged through the first supply flow path 131 downstream of the dialysate preparation device 160, the branch flow path 131x, the dialyzer 130, and the discharge flow path 132. When the dialysis device 130 is operated for a long time, calcium carbonate adheres to the inner surfaces of these flow paths.
　電解水生成装置１４０は、循環流路１１０を流れる逆浸透水を取り込んで洗浄用電解水を生成する。電解水生成装置１４０は、二槽式でもよく、三槽式であってもよい。電解水生成装置は、電解水生成装置で生成される電解水に塩化ナトリウムが混入しない、三槽式であることが好ましい。 The electrolyzed water generator 140 takes in the reverse osmosis water flowing through the circulation flow channel 110 to generate electrolyzed water for cleaning. The electrolyzed water generator 140 may be a two-tank type or a three-tank type. The electrolyzed water generator is preferably a three-tank type in which sodium chloride is not mixed in the electrolyzed water generated by the electrolyzed water generator.
　電解水生成装置１４０が二層式の場合、逆浸透水は、電解水生成装置１４０内において塩化ナトリウムなどの塩が添加されて、電気分解される。電解水生成装置１４０が三槽式である場合、逆浸透水は、電解水生成装置１４０内において塩化ナトリウムなどの塩が添加された水溶液からイオンが供給されつつ、電気分解される。 When the electrolyzed water generator 140 is a two-layer type, the reverse osmosis water is electrolyzed by adding a salt such as sodium chloride in the electrolyzed water generator 140. When the electrolyzed water generator 140 is of a three-tank type, the reverse osmosis water is electrolyzed in the electrolyzed water generator 140 while ions are supplied from an aqueous solution to which a salt such as sodium chloride is added.
　電解水生成装置１４０は、上記電気分解により、酸性電解水およびアルカリ性電解水を同時に生成する。酸性電解水およびアルカリ性電解水の一方が、洗浄用電解水として使用される。酸性電解水は、次亜塩素酸水溶液である。 The electrolyzed water generator 140 simultaneously generates acidic electrolyzed water and alkaline electrolyzed water by the electrolysis. One of the acidic electrolyzed water and the alkaline electrolyzed water is used as the electrolyzed water for cleaning. The acidic electrolyzed water is a hypochlorous acid aqueous solution.
　本実施形態における電解水生成装置１４０は、洗浄用電解水として酸性電解水を使用する状態と、洗浄用電解水としてアルカリ性電解水を使用する状態とを、切り替え可能に構成されている。 The electrolyzed water generating apparatus 140 according to the present embodiment is configured to be switchable between a state of using acidic electrolyzed water as the electrolyzed water for cleaning and a state of using alkaline electrolyzed water as the electrolyzed water for cleaning.
　第１バイパス流路１４１は、循環流路１１０と電解水生成装置１４０とを互いに接続する。電解水生成装置１４０は、第１バイパス流路１４１から電解水生成装置１４０に流入する流体を用いて、上述の電気分解により酸性電解水およびアルカリ性電解水を生成する。 The first bypass flow passage 141 connects the circulation flow passage 110 and the electrolyzed water generating device 140 to each other. The electrolyzed water producing apparatus 140 produces acidic electrolyzed water and alkaline electrolyzed water by the above-mentioned electrolysis using the fluid flowing into the electrolyzed water producing apparatus 140 from the first bypass channel 141.
　第２バイパス流路１４２は、電解水生成装置１４０と第１供給流路１３１とを互いに接続する。これにより、電解水生成装置１４０は、洗浄用電解水を第１供給流路１３１に供給可能である。電解水生成装置１４０は、生成した酸性電解水およびアルカリ性電解水のうちの一方を、洗浄用電解水として第２バイパス流路１４２に送り込む。 The second bypass flow path 142 connects the electrolyzed water generation device 140 and the first supply flow path 131 to each other. As a result, the electrolyzed water generation device 140 can supply the electrolyzed water for cleaning to the first supply flow path 131. The electrolyzed water producing apparatus 140 sends one of the produced acidic electrolyzed water and alkaline electrolyzed water to the second bypass flow path 142 as electrolyzed water for cleaning.
　第２バイパス流路１４２には、第５開閉弁１５０ｅが設けられている。電解水生成装置１４０で電解水を生成しない場合、第５開閉弁は閉状態となっている。電解水生成装置１４０で電解水を生成する場合、第５開閉弁は開状態となっている。図１に示すように、透析を実施する際は、第５開閉弁は閉状態となっている。 The second bypass passage 142 is provided with a fifth opening / closing valve 150e. When the electrolyzed water producing apparatus 140 does not produce electrolyzed water, the fifth on-off valve is in the closed state. When the electrolyzed water producing apparatus 140 produces electrolyzed water, the fifth on-off valve is in an open state. As shown in FIG. 1, when performing dialysis, the fifth on-off valve is closed.
　第１開閉弁１５０ａは、循環流路１１０において、第１バイパス流路１４１との接続部より下流側であって、第１供給流路１３１との接続部より上流側に設けられている。図１に示すように、透析を実施する際は、第１開閉弁１５０ａは開状態となっている。 The first opening / closing valve 150a is provided in the circulation flow channel 110, downstream of the connection portion with the first bypass flow passage 141 and upstream of the connection portion with the first supply flow passage 131. As shown in FIG. 1, when performing dialysis, the first on-off valve 150a is open.
　第２開閉弁１５０ｂは、第１供給流路１３１において、循環流路１１０との接続部、および、第２バイパス流路１４２との接続部、の間に設けられている。図１に示すように、透析を実施する際は、第２開閉弁１５０ｂは開状態となっている。 The second opening / closing valve 150b is provided in the first supply passage 131 between the connection portion with the circulation passage 110 and the connection portion with the second bypass passage 142. As shown in FIG. 1, when performing dialysis, the second on-off valve 150b is open.
　図１に示すように、本実施形態において、透析液調製装置１６０は、第１供給流路１３１において、第２バイパス流路１４２との接続部より透析装置１３０側に設けられている。 As shown in FIG. 1, in the present embodiment, the dialysate preparation device 160 is provided in the first supply flow path 131 closer to the dialyzer 130 than the connection part with the second bypass flow path 142.
　透析が実施される際には、透析液調製装置１６０において、第１供給流路１３１の上流側から供給される逆浸透水と、第１原液と第２原液とが混合されることにより、透析液が調製される。 When dialysis is performed, in the dialysate preparation device 160, the reverse osmosis water supplied from the upstream side of the first supply flow path 131 is mixed with the first stock solution and the second stock solution, so that the dialysis is performed. The liquid is prepared.
　第１原液は、たとえば、カルシウム塩、マグネシウム塩、カリウム塩およびナトリウム塩およびブドウ糖などが水に溶解することにより調製された液体製剤である。第２原液は、炭酸水素ナトリウムなどが水に溶解することにより調製された液体製剤である。 The first stock solution is, for example, a liquid preparation prepared by dissolving calcium salt, magnesium salt, potassium salt and sodium salt, glucose and the like in water. The second stock solution is a liquid preparation prepared by dissolving sodium hydrogen carbonate or the like in water.
　第１原液タンク１７０ａは、透析液調製装置１６０に接続され、透析液調製装置１６０に第１原液を供給する。第１原液タンク１７０ａと、透析液調製装置１６０とは、第１原液供給流路１７２ａを介して互いに接続されている。透析が実施される際には、第１原液タンク１７０ａにおいて、逆浸透水に第１原液用の粉末製剤が溶解することにより、第１原液が調製される。 The first stock solution tank 170a is connected to the dialysate preparation apparatus 160 and supplies the first stock solution to the dialysate preparation apparatus 160. The first stock solution tank 170a and the dialysate preparation device 160 are connected to each other via a first stock solution supply channel 172a. When dialysis is performed, the first stock solution is prepared by dissolving the powder formulation for the first stock solution in the reverse osmosis water in the first stock solution tank 170a.
　第２原液タンク１７０ｂは、透析液調製装置１６０に接続され、透析液調製装置１６０に第２原液を供給する。第２原液タンク１７０ｂと、透析液調製装置１６０とは、第２原液供給流路１７２ｂを介して互いに接続されている。透析が実施される際には、第２原液タンク１７０ｂにおいて、逆浸透水に第２原液用の粉末製剤が溶解することにより、第２原液が調製される。 The second stock solution tank 170b is connected to the dialysate preparation device 160 and supplies the second stock solution to the dialysate preparation device 160. The second stock solution tank 170b and the dialysate preparation device 160 are connected to each other via a second stock solution supply channel 172b. When dialysis is performed, the second stock solution is prepared by dissolving the powder formulation for the second stock solution in the reverse osmosis water in the second stock solution tank 170b.
　第２供給流路１７１は、循環流路１１０と、第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々とを互いに接続する。本実施形態において、第２供給流路１７１は、下流側において、第１原液タンク１７０ａ側と、第２原液タンク１７０ｂ側とに分岐している。 The second supply flow path 171 connects the circulation flow path 110 to each of the first stock solution tank 170a and the second stock solution tank 170b. In the present embodiment, the second supply flow path 171 is branched on the downstream side into a first stock solution tank 170a side and a second stock solution tank 170b side.
　第３バイパス流路１４３は、電解水生成装置１４０と第２供給流路１７１とを互いに接続する。第３バイパス流路１４３は、第２バイパス流路１４２を通流する洗浄用電解水と同一の洗浄用電解水を通流させることができるように構成されている。 The third bypass flow passage 143 connects the electrolyzed water generation device 140 and the second supply flow passage 171 to each other. The third bypass flow passage 143 is configured to allow the same cleaning electrolysis water as the cleaning electrolysis water flowing through the second bypass flow passage 142 to flow.
　第３開閉弁１５０ｃは、第２供給流路１７１において、第１原液タンク１７０ａ、第２原液タンク１７０ｂおよび第３バイパス流路１４３の各々との接続部より循環流路１１０側に設けられている。 The third on-off valve 150c is provided in the second supply passage 171 on the circulation passage 110 side with respect to the connection portion with each of the first stock solution tank 170a, the second stock solution tank 170b, and the third bypass path 143. ..
　図１に示すように、透析が実施される際には、第３開閉弁１５０ｃは開状態となっている。これにより、第２供給流路１７１を介して第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々に、循環流路１１０を通流している逆浸透水が供給される。 As shown in FIG. 1, the third on-off valve 150c is open when dialysis is performed. As a result, the reverse osmosis water flowing through the circulation channel 110 is supplied to each of the first stock solution tank 170a and the second stock solution tank 170b via the second supply channel 171.
　なお、図１に示すように、複数の個人用透析装置１３９の各々は、第２供給流路１７１における第１原液タンク１７０ａ、第２原液タンク１７０ｂおよび第３バイパス流路１４３の各々との接続部の中で最も循環流路１１０側に位置する接続部と、第３開閉弁１５０ｃとの間に接続された第３供給流路１３９ｘを介して、循環流路１１０に接続される。このため、複数の個人用透析装置１３９の各々は、第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々と同様に逆浸透水が供給される。また、後述の洗浄を実施する際も、第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々と同様にして、洗浄用電解水が流れる。なお、循環流路１１０に間接的に接続される個人用透析装置１３９は、１つでもよく、必ずしも設けられていなくてもよい。 Note that, as shown in FIG. 1, each of the plurality of personal dialysis devices 139 is connected to each of the first stock solution tank 170 a, the second stock solution tank 170 b, and the third bypass flow path 143 in the second supply flow path 171. It is connected to the circulation flow channel 110 via a third supply flow channel 139x connected between the third on-off valve 150c and the connection portion located closest to the circulation flow channel 110 side. Therefore, the reverse osmosis water is supplied to each of the plurality of personal dialysis devices 139 in the same manner as the first stock solution tank 170a and the second stock solution tank 170b. Also, when performing the cleaning described below, the electrolytic water for cleaning flows in the same manner as in the first stock solution tank 170a and the second stock solution tank 170b. The number of the personal dialysis device 139 indirectly connected to the circulation flow channel 110 may be one, and may not necessarily be provided.
　第４開閉弁１５０ｄは、第３バイパス流路１４３に設けられている。図１に示すように、透析が実施される際、第４開閉弁１５０ｄは閉状態となっている。これにより、逆浸透水が、第３バイパス流路１４３を経由して電解水生成装置１４０に流入しないようにされている。 The fourth opening / closing valve 150d is provided in the third bypass passage 143. As shown in FIG. 1, when dialysis is performed, the fourth on-off valve 150d is closed. As a result, the reverse osmosis water is prevented from flowing into the electrolyzed water generating device 140 via the third bypass flow passage 143.
　ここで、透析液調製装置１６０、第１原液タンク１７０ａおよび第２原液タンク１７０ｂには、それぞれ、排出流路１６３、第１原液排出流路１７３ａおよび第２原液排出流路１７３ｂが接続されている。 Here, the dialysate preparation device 160, the first stock solution tank 170a, and the second stock solution tank 170b are connected to a discharge channel 163, a first stock solution discharge channel 173a, and a second stock solution discharge channel 173b, respectively. ..
　透析液調製装置１６０内において、透析液の濃度に異常が発生した場合、または、透析液が透析液調製装置１６０内に長時間貯留されていた場合には、透析液調製装置１６０内から、透析液が排出流路１６３に排出される。なお、透析実施時および後述する洗浄を実施する際は、排出流路１６３に透析液または洗浄用電解水が流れていなくてもよい。 If an abnormality occurs in the concentration of the dialysate in the dialysate preparation device 160, or if the dialysate is stored in the dialysate preparation device 160 for a long time, the dialysate preparation device 160 is dialyzed. The liquid is discharged to the discharge channel 163. It should be noted that the dialysate or the electrolyzed water for cleaning does not have to flow in the discharge channel 163 during the dialysis and the cleaning described later.
　第１原液タンク１７０ａ内において、第１原液の濃度に異常が発生した場合、または、第１原液が第１原液タンク１７０ａ内に長時間貯留されていた場合には、第１原液タンク１７０ａ内から、第１原液が第１原液排出流路１７３ａへ排出される。なお、透析実施時および後述する洗浄を実施する際は、第１原液排出流路１７３ａに透析液または洗浄用電解水が流れていなくてもよい。 If an abnormality occurs in the concentration of the first stock solution in the first stock solution tank 170a, or if the first stock solution is stored in the first stock solution tank 170a for a long time, , The first stock solution is discharged to the first stock solution discharge channel 173a. It should be noted that the dialysis solution or the electrolyzed water for cleaning need not flow in the first stock solution discharge flow channel 173a during dialysis and during cleaning as described below.
　第２原液タンク１７０ｂ内において、第２原液の濃度に異常が発生した場合、または、第２原液が第２原液タンク１７０ｂ内に長時間貯留されていた場合には、第２原液タンク１７０ｂ内から、第２原液が第２原液排出流路１７３ｂへ排出される。なお、透析実施時および後述する洗浄を実施する際は、第２原液排出流路１７３ｂに透析液または洗浄用電解水が流れていなくてもよい。 If an abnormality occurs in the concentration of the second stock solution in the second stock solution tank 170b, or if the second stock solution is stored in the second stock solution tank 170b for a long time, the second stock solution tank 170b , The second stock solution is discharged to the second stock solution discharge channel 173b. Note that the dialysis solution or the electrolytic water for cleaning need not flow in the second stock solution discharge flow path 173b during the dialysis and the cleaning described below.
　図１に示すように、中和用配管１８０は、電解水生成装置１４０に接続され、電解水生成装置１４０において生成された酸性電解水およびアルカリ性電解水のうち洗浄用電解水ではない方の電解水として、中和用電解水を排出する。すなわち、洗浄用電解水として酸性電解水が流れる場合、中和用電解水としてアルカリ性電解水が中和用配管１８０に排出される。洗浄用電解水としてアルカリ性電解水が流れる場合、中和用電解水として酸性電解水が中和用配管１８０に排出される。 As shown in FIG. 1, the neutralization pipe 180 is connected to the electrolyzed water producing apparatus 140, and electrolysis of one of the acidic electrolyzed water and the alkaline electrolyzed water produced in the electrolyzed water producing apparatus 140, which is not the electrolysis water for cleaning. Electrolyzed water for neutralization is discharged as water. That is, when acidic electrolyzed water flows as the electrolyzed water for cleaning, alkaline electrolyzed water is discharged to the neutralization pipe 180 as electrolyzed water for neutralization. When alkaline electrolyzed water flows as the electrolyzed water for cleaning, acidic electrolyzed water is discharged to the neutralization pipe 180 as electrolyzed water for neutralization.
　本実施形態に係る透析装置洗浄システム１００は、中和槽１８１をさらに備えている。中和槽１８１は、複数の排出流路１３２の各々の下流側と互いに接続されている。また、中和槽１８１は、複数の排出流路１３９ｙの各々の下流側と互いに接続されている。 The dialysis machine cleaning system 100 according to the present embodiment further includes a neutralization tank 181. The neutralization tank 181 is connected to the downstream side of each of the plurality of discharge flow paths 132. The neutralization tank 181 is connected to the downstream side of each of the plurality of discharge channels 139y.
　中和槽１８１は、中和用配管１８０の下流側と互いに接続されている。すなわち、中和槽１８１には洗浄用電解水および中和用電解水の各々が流入する。このように、中和用配管１８０は、中和用配管１８０から排出された中和用電解水が、透析装置１３０から排出された洗浄用電解水と合流するように構成されている。なお、中和槽１８１は、必ずしも設けられていなくてもよい。 The neutralization tank 181 is connected to the downstream side of the neutralization pipe 180. That is, the electrolysis water for cleaning and the electrolysis water for neutralization each flow into the neutralization tank 181. In this way, the neutralization pipe 180 is configured such that the neutralized electrolyzed water discharged from the neutralization pipe 180 joins with the cleaning electrolyzed water discharged from the dialyzer 130. The neutralization tank 181 does not necessarily have to be provided.
　上述したように、洗浄用電解水として酸性電解水を使用しているとき、中和用電解水はアルカリ性電解水である。また、洗浄用電解水としてアルカリ性電解水を使用しているとき、中和用電解水は酸性電解水である。このため、中和槽１８１内においては、洗浄用電解水が酸性電解水およびアルカリ性電解水のいずれであっても、中和用電解水によって中和される。洗浄用電解水は、中和槽１８１で中和された後、中和槽１８１から排出される。 As mentioned above, when acidic electrolyzed water is used as the electrolyzed water for cleaning, the electrolyzed water for neutralization is alkaline electrolyzed water. When alkaline electrolyzed water is used as the electrolyzed water for cleaning, the electrolyzed water for neutralization is acidic electrolyzed water. Therefore, in the neutralization tank 181, whether the electrolytic water for cleaning is acidic electrolytic water or alkaline electrolytic water is neutralized by the electrolytic water for neutralization. The electrolytic water for cleaning is neutralized in the neutralization tank 181, and then discharged from the neutralization tank 181.
　さらに、排出流路１６３の下流側も、中和槽１８１と互いに接続されている。透析液調製装置１６０内における透析液が排出される際には、透析液が、排出流路１６３を通過して、中和槽１８１に流入する。 Furthermore, the downstream side of the discharge flow channel 163 is also connected to the neutralization tank 181. When the dialysate in the dialysate preparation device 160 is discharged, the dialysate passes through the discharge channel 163 and flows into the neutralization tank 181.
　なお、透析液調製装置１６０内における透析液を排出させたあと、透析液調製装置１６０を上記洗浄用電解水で洗浄してもよい。この場合、排出流路１６３を通じて、洗浄に使用した洗浄用電解水を中和槽１８１に流入させることで、洗浄用電解水を排出する。 The dialysate preparation device 160 may be washed with the above-mentioned electrolyzed water for washing after the dialysate preparation device 160 is drained. In this case, the electrolytic water for cleaning is discharged by flowing the electrolytic water for cleaning used for cleaning into the neutralization tank 181 through the discharge channel 163.
　第１原液排出流路１７３ａの下流側も、中和槽１８１と互いに接続されている。第１原液タンク１７０ａ内における第１原液が排出される際には、第１原液が、第１原液排出流路１７３ａを通過して、中和槽１８１に流入する。 The downstream side of the first stock solution discharge flow path 173a is also connected to the neutralization tank 181. When the first stock solution in the first stock solution tank 170a is discharged, the first stock solution passes through the first stock solution discharge flow path 173a and flows into the neutralization tank 181.
　なお、第１原液タンク１７０ａ内における第１原液を排出させたあと、第１原液タンク１７０ａを上記洗浄用電解水で洗浄してもよい。この場合、第１原液排出流路１７３ａを通じて、洗浄に使用した洗浄用電解水を中和槽１８１に流入させることで、洗浄用電解水を排出する。 The first stock solution tank 170a may be washed with the above-mentioned electrolytic water for cleaning after the first stock solution in the first stock solution tank 170a is discharged. In this case, the electrolytic water for cleaning is discharged by flowing the electrolytic water for cleaning used for cleaning into the neutralization tank 181 through the first stock solution discharge flow path 173a.
　第２原液排出流路１７３ｂの下流側も、中和槽１８１と互いに接続されている。第２原液タンク１７０ｂ内における第２原液が排出される際には、第２原液が、第２原液排出流路１７３ｂを通過して、中和槽１８１に流入する。 The downstream side of the second stock solution discharge flow path 173b is also connected to the neutralization tank 181. When the second undiluted solution in the second undiluted solution tank 170b is discharged, the second undiluted solution passes through the second undiluted solution discharge passage 173b and flows into the neutralization tank 181.
　なお、第２原液タンク１７０ｂ内における第２原液を排出させたあと、第２原液タンク１７０ｂを上記洗浄用電解水で洗浄してもよい。この場合、第２原液排出流路１７３ｂを通じて、洗浄に使用した洗浄用電解水を中和槽１８１に流入させることで、洗浄用電解水を排出する。 Note that the second stock solution tank 170b may be washed with the above-described electrolytic water for cleaning after the second stock solution in the second stock solution tank 170b is discharged. In this case, the electrolytic water for cleaning is discharged by flowing the electrolytic water for cleaning used for cleaning into the neutralization tank 181 through the second stock solution discharge channel 173b.
　以下、本発明の一実施形態に係る透析装置洗浄システム１００において、各構成を洗浄をする際の動作について説明する。なお、個人用透析装置１３９を洗浄する際の動作は、第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々と同じであるため、説明を省略する。 The operation of cleaning each component in the dialysis machine cleaning system 100 according to the embodiment of the present invention will be described below. The operation of cleaning the personal dialysis device 139 is the same as that of each of the first stock solution tank 170a and the second stock solution tank 170b, and thus the description thereof is omitted.
　まず、逆浸透水生成装置１２０内のタンクを洗浄する工程について説明する。図２は、本発明の一実施形態に係る透析装置洗浄システムにおいて、逆浸透水生成装置内のタンクを洗浄している状態を示す回路図である。図２に示すように、透析装置洗浄システム１００において、逆浸透水生成装置１２０内のタンクを洗浄する際は、第１開閉弁１５０ａは閉状態となっており、第２開閉弁１５０ｂは開状態となっている。 First, the process of cleaning the tank in the reverse osmosis water generator 120 will be described. FIG. 2 is a circuit diagram showing a state in which the tank in the reverse osmosis water generator is being washed in the dialysis machine washing system according to the embodiment of the present invention. As shown in FIG. 2, in the dialysis machine cleaning system 100, when cleaning the tank in the reverse osmosis water generator 120, the first on-off valve 150a is in the closed state and the second on-off valve 150b is in the open state. Has become.
　逆浸透水生成装置１２０内のタンクを洗浄する際、電解水生成装置１４０は、洗浄用電解水として、酸性電解水を第２バイパス流路１４２に流入させる。酸性電解水のｐＨ値は、たとえば３であり、酸性電解水における次亜塩素酸濃度はおよそ５０ｐｐｍである。 When cleaning the tank in the reverse osmosis water generator 120, the electrolyzed water generator 140 causes acidic electrolyzed water to flow into the second bypass flow path 142 as electrolyzed water for cleaning. The pH value of the acidic electrolyzed water is, for example, 3, and the hypochlorous acid concentration in the acidic electrolyzed water is about 50 ppm.
　電解水生成装置１４０によって生成された酸性電解水は、第２バイパス流路１４２から、第１供給流路１３１に流れる。第１供給流路１３１に流入した酸性電解水は、循環流路１１０に流入する。第１供給流路１３１から循環流路１１０に流入した酸性電解水は、逆浸透水生成装置１２０に流れる。 The acidic electrolyzed water produced by the electrolyzed water producing apparatus 140 flows from the second bypass passage 142 to the first supply passage 131. The acidic electrolyzed water that has flowed into the first supply flow path 131 flows into the circulation flow path 110. The acidic electrolyzed water that has flowed into the circulation flow channel 110 from the first supply flow channel 131 flows to the reverse osmosis water generation device 120.
　逆浸透水生成装置１２０において、酸性電解水は、逆浸透水生成装置１２０によって生成される逆浸透水と混合されて希釈される。これにより、次亜塩素酸濃度がおよそ１ｐｐｍの酸性電解水が、逆浸透水生成装置１２０にて生成される。 In the reverse osmosis water generator 120, the acidic electrolyzed water is mixed with the reverse osmosis water generated by the reverse osmosis water generator 120 and diluted. As a result, acidic electrolyzed water having a hypochlorous acid concentration of about 1 ppm is produced by the reverse osmosis water production apparatus 120.
　この次亜塩素酸濃度が１ｐｐｍの酸性電解水は、逆浸透水生成装置１２０から循環流路１１０に再び流入する。循環流路１１０を循環した酸性電解水は、循環流路１１０から電解水生成装置１４０に流入する。電解水生成装置１４０は、逆浸透水の代わりにこの希釈された酸性電解水を用いて上述の電気分解を行ない、次亜塩素酸濃度がおよそ５０ｐｐｍの酸性電解水を生成する。 The acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into the circulation flow channel 110 again from the reverse osmosis water generator 120. The acidic electrolyzed water that has circulated in the circulation flow channel 110 flows into the electrolyzed water generation device 140 from the circulation flow channel 110. The electrolyzed water producing apparatus 140 uses the diluted acidic electrolyzed water instead of the reverse osmosis water to perform the electrolysis described above, and produces the acidic electrolyzed water having a hypochlorous acid concentration of about 50 ppm.
　このように、電解水生成装置１４０から、第２バイパス流路１４２、第１供給流路１３１および循環流路１１０を通じて逆浸透水生成装置１２０に到達するまでの区間においては、次亜塩素酸濃度がおよそ５０ｐｐｍの酸性電解水が通流する。逆浸透水生成装置１２０から、循環流路１１０を通じて電解水生成装置１４０に到達するまでの区間においては、次亜塩素酸濃度がおよそ１ｐｐｍの酸性電解水が通流する。 Thus, in the section from the electrolyzed water producing device 140 to the reverse osmosis water producing device 120 through the second bypass flow passage 142, the first supply flow passage 131, and the circulation flow passage 110, the hypochlorous acid concentration About 50 ppm of acidic electrolyzed water flows through. In the section from the reverse osmosis water generator 120 to the electrolytic water generator 140 through the circulation flow path 110, the acidic electrolyzed water having a hypochlorous acid concentration of about 1 ppm flows.
　よって、透析装置洗浄システム１００において、逆浸透水生成装置１２０内のタンクを洗浄する際は、逆浸透水生成装置１２０内のタンクが、次亜塩素酸濃度が１ｐｐｍの酸性電解水によって洗浄殺菌される。 Therefore, in the dialyzer cleaning system 100, when cleaning the tank in the reverse osmosis water generator 120, the tank in the reverse osmosis water generator 120 is cleaned and sterilized with the acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm. It
　また、本実施形態においては、逆浸透水生成装置１２０内のタンクを洗浄する際は、第３開閉弁１５０ｃは開状態となっており、第４開閉弁１５０ｄは閉状態となっている。よって、逆浸透水生成装置１２０内のタンクを洗浄する際は、洗浄用電解水である酸性電解水は、第３バイパス流路１４３に流入しない。これにより、電解水生成装置１４０が直接的に酸性電解水を供給する流路は、第２バイパス流路１４２のみとなる。 Further, in the present embodiment, when cleaning the tank in the reverse osmosis water generator 120, the third opening / closing valve 150c is in the open state and the fourth opening / closing valve 150d is in the closed state. Therefore, when cleaning the tank in the reverse osmosis water generation apparatus 120, the acidic electrolyzed water as the electrolyzed water for cleaning does not flow into the third bypass flow passage 143. As a result, the flow path through which the electrolyzed water generator 140 directly supplies the acidic electrolyzed water is only the second bypass flow path 142.
　本実施形態に係る透析装置洗浄システム１００において、逆浸透水生成装置１２０内のタンクを洗浄する際は、逆浸透水生成装置１２０内のタンクから、次亜塩素酸濃度が１ｐｐｍの酸性電解水の一部が排出されている。これにより、循環流路１１０を流れる酸性電解水の流量が、閾値で維持されている。このため、逆浸透水生成装置１２０内のタンクを洗浄する際には、酸性電解水は、透析液調製装置１６０、第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々には、流入しない。 In the dialyzer cleaning system 100 according to the present embodiment, when cleaning the tank in the reverse osmosis water generator 120, acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm is removed from the tank in the reverse osmosis water generator 120. Some have been discharged. As a result, the flow rate of the acidic electrolyzed water flowing through the circulation channel 110 is maintained at the threshold value. Therefore, when cleaning the tank in the reverse osmosis water generator 120, the acidic electrolyzed water does not flow into each of the dialysate preparation device 160, the first stock solution tank 170a, and the second stock solution tank 170b.
　すなわち、透析装置洗浄システム１００は、循環流路１１０を流れる酸性電解水の流量が閾値を超えた際に、透析液調製装置１６０、第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々に酸性電解水が流れるように構成されている。 That is, when the flow rate of the acidic electrolyzed water flowing through the circulation flow channel 110 exceeds the threshold value, the dialyzer cleaning system 100 performs acidic electrolysis on each of the dialysate preparation device 160, the first stock solution tank 170a, and the second stock solution tank 170b. It is designed to allow water to flow.
　透析装置洗浄システム１００は、逆浸透水生成装置１２０内のタンクから排出される酸性電解水が、中和用配管１８０を流れるアルカリ性電解水と合流するように、構成されていることが好ましい。 The dialyzer cleaning system 100 is preferably configured so that the acidic electrolyzed water discharged from the tank in the reverse osmosis water generator 120 joins with the alkaline electrolyzed water flowing through the neutralization pipe 180.
　なお、必ずしも、逆浸透水生成装置１２０内のタンクから酸性電解水が排出されなくてもよい。この場合、循環流路１１０を流れる酸性電解水の閾値を超えた超過分が、循環流路１１０から第１バイパス流路１４１、第２バイパス流路１４２および第１供給流路１３１を通じて透析液調製装置１６０に流入する。同様に、循環流路１１０から第２供給流路１７１を通じて第１原液タンク１７０ａに流入した酸性電解水の超過分が、第１原液供給流路１７２ａを通じて透析液調製装置１６０に流入する。また、循環流路１１０から第２供給流路１７１を通じて第２原液タンク１７０ｂに流入した酸性電解水の超過分が、第２原液供給流路１７２ｂを通じて透析液調製装置１６０に流入する。 Note that the acidic electrolyzed water does not necessarily have to be discharged from the tank in the reverse osmosis water generator 120. In this case, the excess amount of the acidic electrolyzed water flowing through the circulation channel 110 that exceeds the threshold value is adjusted from the circulation channel 110 through the first bypass channel 141, the second bypass channel 142, and the first supply channel 131 to prepare the dialysate. Flow into device 160. Similarly, the excess amount of the acidic electrolyzed water that has flowed into the first stock solution tank 170a from the circulation flow path 110 through the second supply path 171 flows into the dialysate preparation device 160 through the first stock solution supply path 172a. Further, the excess amount of the acidic electrolyzed water that has flowed from the circulation flow path 110 into the second stock solution tank 170b through the second supply path 171 flows into the dialysate preparation device 160 through the second stock solution supply path 172b.
　透析液調製装置１６０に流入した酸性電解水の超過分は、第１供給流路１３１、複数の透析装置１３０、複数の分岐流路１３１ｘ、複数の排出流路１３２、および、中和槽１８１を順次流れ、排出される。 Excessive amount of acidic electrolyzed water that has flowed into the dialysate preparation device 160 flows through the first supply flow path 131, the plurality of dialysis machines 130, the plurality of branch flow paths 131x, the plurality of discharge flow paths 132, and the neutralization tank 181. It flows in sequence and is discharged.
　次に、次亜塩素酸濃度が１ｐｐｍの酸性電解水によって弱酸洗浄する工程について説明する。透析装置洗浄システム１００において、弱酸洗浄する際、各開閉弁の状態は、図１に示す状態と同様である。弱酸洗浄する際は、電解水生成装置１４０は、酸性電解水およびアルカリ性電解水の各々を生成していない。 Next, the process of weak acid cleaning with acidic electrolyzed water with a hypochlorous acid concentration of 1 ppm will be described. In the dialyzer cleaning system 100, when performing weak acid cleaning, the state of each on-off valve is the same as the state shown in FIG. During the weak acid cleaning, the electrolyzed water producing apparatus 140 does not produce each of the acidic electrolyzed water and the alkaline electrolyzed water.
　弱酸洗浄する際、逆浸透水生成装置１２０は、生成した逆浸透水を循環流路１１０に流入させる。これにより、循環流路１１０から、次亜塩素酸濃度が１ｐｐｍの酸性電解水が各流路に流入する。 When performing weak acid cleaning, the reverse osmosis water generation device 120 causes the generated reverse osmosis water to flow into the circulation flow channel 110. As a result, the acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into each flow path from the circulation flow path 110.
　具体的には、次亜塩素酸濃度が１ｐｐｍの酸性電解水が、循環流路１１０から、第１供給流路１３１を通じて透析液調製装置１６０に流入する。同様に、次亜塩素酸濃度が１ｐｐｍの酸性電解水が、循環流路１１０から、第２供給流路１７１、第１原液タンク１７０ａおよび第１原液供給流路１７２ａを通じて透析液調製装置１６０に流入する。また、次亜塩素酸濃度が１ｐｐｍの酸性電解水が、循環流路１１０から、第２供給流路１７１、第２原液タンク１７０ｂおよび第２原液供給流路１７２ｂを通じて透析液調製装置１６０に流入する。 Specifically, acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into the dialysate preparation device 160 from the circulation flow path 110 through the first supply flow path 131. Similarly, acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into the dialysate preparation device 160 from the circulation channel 110 through the second supply channel 171, the first stock solution tank 170a, and the first stock solution supply channel 172a. To do. In addition, the acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm flows into the dialysate preparation device 160 from the circulation channel 110 through the second supply channel 171, the second stock solution tank 170b, and the second stock solution supply channel 172b. ..
　透析液調製装置１６０に流入した次亜塩素酸濃度が１ｐｐｍの酸性電解水は、第１供給流路１３１、複数の透析装置１３０、複数の分岐流路１３１ｘ、複数の排出流路１３２、および、中和槽１８１を順次流れ、排出される。 The acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm that has flowed into the dialysate preparation device 160 has a first supply flow path 131, a plurality of dialysis machines 130, a plurality of branch flow paths 131x, a plurality of discharge flow paths 132, and The neutralization tank 181 sequentially flows and is discharged.
　次に、次亜塩素酸素濃度が５０ｐｐｍの酸性電解水によって強酸洗浄する工程について説明する。図３は、本発明の一実施形態に係る透析装置洗浄システムにおいて、強酸洗浄している状態を示す回路図である。 Next, the step of performing strong acid cleaning with acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm will be described. FIG. 3 is a circuit diagram showing a state in which strong acid cleaning is performed in the dialysis machine cleaning system according to the embodiment of the present invention.
　図３に示すように、透析装置洗浄システム１００において、強酸洗浄する際は、第１開閉弁１５０ａが開状態、第２開閉弁１５０ｂが閉状態、第３開閉弁１５０ｃが閉状態、第４開閉弁１５０ｄが開状態、第５開閉弁１５０ｅが開状態となっている。 As shown in FIG. 3, in the dialysis machine cleaning system 100, when performing strong acid cleaning, the first opening / closing valve 150a is open, the second opening / closing valve 150b is closed, the third opening / closing valve 150c is closed, and the fourth opening / closing is performed. The valve 150d is open and the fifth on-off valve 150e is open.
　強酸洗浄する際は、電解水生成装置１４０は、透析を実施する際と同様に、洗浄用電解水として酸性電解水を生成する。 When performing strong acid cleaning, the electrolyzed water generating apparatus 140 generates acidic electrolyzed water as electrolyzed water for cleaning, as in the case of performing dialysis.
　電解水生成装置１４０によって生成された次亜塩素酸素濃度が５０ｐｐｍの酸性電解水は、第２バイパス流路１４２から、第１供給流路１３１に流入する。第２開閉弁１５０ｂが開状態となっているため、第１供給流路１３１に流入した次亜塩素酸素濃度が５０ｐｐｍの酸性電解水は、第１供給流路１３１を通じて透析液調製装置１６０に流入する。 The acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm produced by the electrolyzed water producing device 140 flows into the first supply passage 131 from the second bypass passage 142. Since the second opening / closing valve 150b is in the open state, the acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm that has flowed into the first supply flow path 131 flows into the dialysate preparation device 160 through the first supply flow path 131. To do.
　透析液調製装置１６０に流入した次亜塩素酸濃度が５０ｐｐｍの酸性電解水は、第１供給流路１３１、複数の透析装置１３０、複数の分岐流路１３１ｘ、複数の排出流路１３２、および、中和槽１８１を順次流れ、排出される。 The acidic electrolyzed water having a hypochlorous acid concentration of 50 ppm that has flowed into the dialysate preparation device 160 has a first supply flow path 131, a plurality of dialysis machines 130, a plurality of branch flow paths 131x, a plurality of discharge flow paths 132, and The neutralization tank 181 sequentially flows and is discharged.
　このとき、循環流路１１０においては、次亜塩素酸濃度が１ｐｐｍ以下の酸性電解水が循環しており、時間の経過とともに次亜塩素酸濃度が低下する。このように、強酸洗浄する際は、次亜塩素酸濃度が５０ｐｐｍの酸性電解水は、循環流路１１０に流入することなく、透析液調製装置１６０および透析装置１３０を通過するように通流する。これにより、透析装置１３０および透析液調製装置１６０の各々を、次亜塩素酸濃度５０ｐｐｍの酸性電解水で洗浄することができる。 At this time, in the circulation channel 110, acidic electrolyzed water having a hypochlorous acid concentration of 1 ppm or less is circulated, and the hypochlorous acid concentration decreases over time. As described above, during the strong acid cleaning, the acidic electrolyzed water having a hypochlorous acid concentration of 50 ppm flows through the dialysate preparation device 160 and the dialyzer 130 without flowing into the circulation flow channel 110. .. As a result, each of the dialyzer 130 and the dialysate preparation device 160 can be washed with acidic electrolyzed water having a hypochlorous acid concentration of 50 ppm.
　また、強酸洗浄する際は、電解水生成装置１４０は、第３バイパス流路１４３にも次亜塩素酸濃度が５０ｐｐｍの酸性電解水を供給する。第３開閉弁１５０ｃが閉状態となっているため、第３バイパス流路１４３に流入した次亜塩素酸素濃度が５０ｐｐｍの酸性電解水は、第２供給流路１７１を通じて第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々に流入する。第１原液タンク１７０ａに流入した次亜塩素酸素濃度が５０ｐｐｍの酸性電解水は、第１原液供給流路１７２ａを通じて透析液調製装置１６０に流入する。第２原液タンク１７０ｂに流入した次亜塩素酸素濃度が５０ｐｐｍの酸性電解水が、第２原液供給流路１７２ｂを通じて透析液調製装置１６０に流入する。 Further, when performing strong acid cleaning, the electrolyzed water generator 140 also supplies the electrolyzed electrolyzed water having a hypochlorous acid concentration of 50 ppm to the third bypass passage 143. Since the third on-off valve 150c is in the closed state, the acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm that has flowed into the third bypass flow passage 143 is discharged through the second supply flow passage 171 to the first stock solution tank 170a and the It flows into each of the two stock solution tanks 170b. The acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm that has flowed into the first stock solution tank 170a flows into the dialysate preparation device 160 through the first stock solution supply channel 172a. The acidic electrolyzed water having a hypochlorous oxygen concentration of 50 ppm, which has flowed into the second stock solution tank 170b, flows into the dialysate preparation device 160 through the second stock solution supply channel 172b.
　このように、強酸洗浄する際は、次亜塩素酸濃度が５０ｐｐｍの酸性電解水が、循環流路１１０に流入することなく、第１原液タンク１７０ａおよび第２原液タンク１７０ｂを通過するように通流する。これにより、第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々を、次亜塩素酸濃度５０ｐｐｍの酸性電解水で洗浄することができる。 Thus, when performing strong acid cleaning, acidic electrolyzed water with a hypochlorous acid concentration of 50 ppm is passed through the first stock solution tank 170a and the second stock solution tank 170b without flowing into the circulation flow channel 110. Shed. Thus, each of the first stock solution tank 170a and the second stock solution tank 170b can be washed with acidic electrolyzed water having a hypochlorous acid concentration of 50 ppm.
　強酸洗浄する際は、電解水生成装置１４０は、中和用配管１８０に、アルカリ性電解水を供給する。アルカリ性電解水のｐＨ値は、およそ１１である。中和用配管１８０を流れたアルカリ性電解水は、排出流路１３２を流れた酸性電解水と、中和槽１８１にて中和されて排出される。 When performing strong acid cleaning, the electrolyzed water generator 140 supplies alkaline electrolyzed water to the neutralization pipe 180. The pH value of alkaline electrolyzed water is approximately 11. The alkaline electrolyzed water that has flowed through the neutralization pipe 180 is neutralized with the acidic electrolyzed water that has flowed through the discharge flow path 132 in the neutralization tank 181, and then discharged.
　次に、アルカリ性電解水によってアルカリ洗浄する工程について説明する。透析装置洗浄システム１００において、アルカリ洗浄する際、各開閉弁の状態は、図３に示す状態と同様である。 Next, the process of alkaline cleaning with alkaline electrolyzed water will be explained. In the dialysis machine cleaning system 100, the state of each on-off valve at the time of alkali cleaning is the same as the state shown in FIG.
　アルカリ洗浄する際は、電解水生成装置１４０は、洗浄用電解水としてアルカリ性電解水を生成する。電解水生成装置１４０は、中和用電解水として酸性電解水を生成する。すなわち、アルカリ洗浄する際は、第２バイパス流路１４２に流れていた酸性電解水を、アルカリ性電解水に切り替えるとともに、中和用配管１８０に流れていたアルカリ性電解水を、酸性電解水に切り替える。アルカリ性電解水のｐＨ値は、およそ１１である。 When performing alkaline cleaning, the electrolyzed water generation device 140 generates alkaline electrolyzed water as cleaning electrolyzed water. The electrolyzed water producing device 140 produces acidic electrolyzed water as the electrolyzed water for neutralization. That is, when performing alkaline cleaning, the acidic electrolyzed water flowing in the second bypass flow path 142 is switched to alkaline electrolyzed water, and the alkaline electrolyzed water flowing in the neutralization pipe 180 is switched to acidic electrolyzed water. The pH value of alkaline electrolyzed water is approximately 11.
　アルカリ洗浄する際は、アルカリ性電解水が、循環流路１１０に流入することなく、透析液調製装置１６０、透析装置１３０、第１原液タンク１７０ａおよび第２原液タンク１７０ｂを通過するように通流する。これにより、透析液調製装置１６０、透析装置１３０、第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々を、アルカリ性電解水で洗浄することができる。 During alkaline cleaning, the alkaline electrolyzed water flows through the dialysate preparation device 160, the dialysis device 130, the first stock solution tank 170a, and the second stock solution tank 170b without flowing into the circulation channel 110. .. Thus, each of the dialysate preparation device 160, the dialyzer 130, the first stock solution tank 170a, and the second stock solution tank 170b can be washed with alkaline electrolyzed water.
　本実施形態に係る透析装置洗浄システム１００においては、酸性電解水で洗浄したのちにアルカリ性電解水で洗浄を行なうことにより、透析装置１３０の透析液回路などに付着した炭酸カルシウムを酸性電解水で除去したうえで、蛋白成分およびケイ素含有成分の各々をアルカリ電解水で除去することができる。その結果、透析装置１３０の透析液回路における付着物を効果的に除去することができる。 In the dialyzer cleaning system 100 according to the present embodiment, the calcium carbonate adhering to the dialysate circuit of the dialyzer 130 is removed by acidic electrolyzed water by cleaning with acidic electrolyzed water and then alkaline electrolyzed water. Then, each of the protein component and the silicon-containing component can be removed with alkaline electrolyzed water. As a result, the deposits in the dialysate circuit of the dialyzer 130 can be effectively removed.
　次に、逆浸透水によって水洗浄する工程について説明する。透析装置洗浄システム１００において、水洗浄する際、各開閉弁の状態は、図１に示す状態と同様である。 Next, the process of washing with reverse osmosis water will be explained. In the dialysis machine cleaning system 100, the state of each on-off valve when washing with water is the same as the state shown in FIG.
　水洗浄する際は、電解水生成装置１４０は、酸性電解水およびアルカリ性電解水の各々を生成していない。水洗浄する際、逆浸透水生成装置１２０は、生成した逆浸透水を循環流路１１０に流入させる。 When electrolyzing with water, the electrolyzed water producing apparatus 140 does not produce acidic electrolyzed water or alkaline electrolyzed water. When washing with water, the reverse osmosis water generation apparatus 120 causes the generated reverse osmosis water to flow into the circulation channel 110.
　循環流路１１０を流れる逆浸透水が、循環流路１１０から、第１供給流路１３１を通じて透析液調製装置１６０に流入する。同様に、循環流路１１０から第２供給流路１７１を通じて第１原液タンク１７０ａに流入した逆浸透水が、第１原液供給流路１７２ａを通じて透析液調製装置１６０に流入する。また、循環流路１１０から第２供給流路１７１を通じて第２原液タンク１７０ｂに流入した逆浸透水が、第２原液供給流路１７２ｂを通じて透析液調製装置１６０に流入する。 Reverse osmosis water flowing through the circulation flow channel 110 flows into the dialysate preparation device 160 from the circulation flow channel 110 through the first supply flow channel 131. Similarly, the reverse osmosis water that has flowed from the circulation channel 110 into the first stock solution tank 170a through the second supply channel 171 flows into the dialysate preparation apparatus 160 through the first stock solution supply channel 172a. In addition, the reverse osmosis water that has flowed from the circulation channel 110 into the second stock solution tank 170b through the second supply channel 171 flows into the dialysate preparation device 160 through the second stock solution supply channel 172b.
　透析液調製装置１６０に流入した逆浸透水は、第１供給流路１３１、複数の透析装置１３０、複数の分岐流路１３１ｘ、複数の排出流路１３２、および、中和槽１８１を順次流れ、排出される。 The reverse osmosis water that has flowed into the dialysate preparation device 160 sequentially flows through the first supply flow path 131, the plurality of dialysis machines 130, the plurality of branch flow paths 131x, the plurality of discharge flow paths 132, and the neutralization tank 181. Is discharged.
　上記の一連の工程により、本実施形態に係る透析装置洗浄システム１００において、酸性電解水およびアルカリ性電解水を用いて、透析装置１３０の透析液回路を洗浄することが可能である。 By the series of steps described above, in the dialyzer cleaning system 100 according to the present embodiment, it is possible to clean the dialysate circuit of the dialyzer 130 using acidic electrolyzed water and alkaline electrolyzed water.
　なお、本実施形態に係る透析装置洗浄システム１００においては、透析装置１３０の透析液回路を洗浄せずに透析液調製装置１６０を洗浄することもできる。この場合、上記の一連の工程において第１供給流路１３１を流れる洗浄用電解水などの液体は、排出流路１６３を通過して中和槽１８１に流入するように制御される。 In the dialyzer cleaning system 100 according to the present embodiment, the dialysate preparation device 160 can be cleaned without cleaning the dialysate circuit of the dialyzer 130. In this case, in the series of steps described above, the liquid such as the electrolytic water for cleaning flowing through the first supply flow path 131 is controlled so as to pass through the discharge flow path 163 and flow into the neutralization tank 181.
　本実施形態に係る透析装置洗浄システム１００においては、透析装置１３０の透析液回路および透析液調製装置１６０を洗浄せずに、第１原液タンク１７０ａを洗浄することもできる。この場合、上記の一連の工程において第１原液供給流路１７２ａを流れる洗浄用電解水などの液体は、第１原液排出流路１７３ａを通過して中和槽１８１に流入するように制御される。 In the dialyzer cleaning system 100 according to the present embodiment, the first stock solution tank 170a can be cleaned without cleaning the dialysate circuit of the dialyzer 130 and the dialysate preparation device 160. In this case, in the series of steps described above, the liquid such as the electrolyzed water for cleaning flowing through the first stock solution supply flow path 172a is controlled to pass through the first stock solution discharge flow path 173a and flow into the neutralization tank 181. ..
　本実施形態に係る透析装置洗浄システム１００においては、透析装置１３０の透析液回路および透析液調製装置１６０を洗浄せずに、第２原液タンク１７０ｂを洗浄することもできる。この場合、上記の一連の工程において第２原液供給流路１７２ｂを流れる洗浄用電解水などの液体は、第２原液排出流路１７３ｂを通過して中和槽１８１に流入するように制御される。 In the dialyzer cleaning system 100 according to the present embodiment, the second stock solution tank 170b can be cleaned without cleaning the dialysate circuit of the dialyzer 130 and the dialysate preparation device 160. In this case, in the series of steps described above, the liquid such as the electrolyzed water for cleaning flowing through the second stock solution supply flow path 172b is controlled so as to pass through the second stock solution discharge flow path 173b and flow into the neutralization tank 181. ..
　さらに、本実施形態に係る透析装置洗浄システム１００においては、循環流路１１０を熱水によって洗浄することも可能である。図４は、本発明の一実施形態に係る透析装置洗浄システムにおいて、熱水洗浄している状態を示す回路図である。 Further, in the dialysis machine cleaning system 100 according to the present embodiment, the circulation channel 110 can be cleaned with hot water. FIG. 4 is a circuit diagram showing a state in which hot water washing is performed in the dialysis machine washing system according to the embodiment of the present invention.
　図４に示すように、熱水洗浄する際は、透析装置洗浄システム１００は、第１開閉弁１５０ａが開状態、第２開閉弁１５０ｂが閉状態、第３開閉弁１５０ｃが閉状態、第４開閉弁１５０ｄが閉状態となっている。 As shown in FIG. 4, when hot water washing is performed, in the dialysis machine washing system 100, the first opening / closing valve 150a is open, the second opening / closing valve 150b is closed, the third opening / closing valve 150c is closed, and the fourth opening / closing valve 150c is closed. The on-off valve 150d is closed.
　熱水洗浄する際は、逆浸透水生成装置が１２０に設けられたヒータによって、循環流路１１０を流れる逆浸透水が加熱される。加熱された逆浸透水が循環流路１１０を循環することで、循環流路１１０が殺菌処理される。 When performing hot water cleaning, the reverse osmosis water flowing through the circulation flow channel 110 is heated by the heater provided in the reverse osmosis water generator 120. The heated reverse osmosis water circulates in the circulation flow channel 110, so that the circulation flow channel 110 is sterilized.
　また、図４に示すように、熱水洗浄する際は、透析装置１３０、電解水生成装置１４０、透析液調製装置１６０、第１原液タンク１７０ａおよび第２原液タンク１７０ｂの各々に熱水が流入しない。これにより、熱水処理による上記各装置の損傷を防止することができる。 Further, as shown in FIG. 4, when hot water is washed, hot water flows into each of the dialyzer 130, the electrolyzed water generator 140, the dialysate preparation device 160, the first stock solution tank 170a, and the second stock solution tank 170b. do not do. As a result, it is possible to prevent damage to the above devices due to hot water treatment.
　上記のように、本発明の一実施形態に係る透析装置洗浄システム１００においては、第１バイパス流路１４１が、循環流路１１０と電解水生成装置１４０とを互いに接続する。第２バイパス流路１４２が、電解水生成装置１４０と第１供給流路１３１とを互いに接続する。第１開閉弁１５０ａが、循環流路１１０において、第１バイパス流路１４１との接続部より下流側であって、第１供給流路１３１との接続部より上流側に設けられている。第２開閉弁１５０ｂが、第１供給流路１３１において、循環流路１１０との接続部、および、第２バイパス流路１４２との接続部、の間に設けられている。これにより、透析装置１３０を洗浄する酸性電解水より次亜塩素酸の濃度が低い酸性電解水によって、逆浸透水の循環流路を洗浄可能となる。その結果、循環流路１１０のうちステンレス鋼で構成されている部分が次亜塩素酸の濃度が高い酸性電解水に長時間晒されることにより腐食して経時的に劣化することを抑制できる。 As described above, in the dialysis machine cleaning system 100 according to the embodiment of the present invention, the first bypass flow channel 141 connects the circulation flow channel 110 and the electrolyzed water generating device 140 to each other. The second bypass flow passage 142 connects the electrolyzed water generation device 140 and the first supply flow passage 131 to each other. The first opening / closing valve 150a is provided in the circulation flow channel 110, downstream of the connection portion with the first bypass flow passage 141 and upstream of the connection portion with the first supply flow passage 131. The second opening / closing valve 150b is provided in the first supply passage 131 between the connection portion with the circulation passage 110 and the connection portion with the second bypass passage 142. As a result, it is possible to wash the circulation passage of the reverse osmosis water with the acidic electrolyzed water having a lower concentration of hypochlorous acid than the acidic electrolyzed water for washing the dialyzer 130. As a result, it is possible to prevent the portion of the circulation flow channel 110, which is made of stainless steel, from being corroded and deteriorated over time due to long-term exposure to acidic electrolyzed water having a high concentration of hypochlorous acid.
　本発明の一実施形態に係る透析装置洗浄システム１００においては、透析液調製装置１６０が、第１供給流路１３１において、第２バイパス流路１４２との接続部より透析装置１３０側に設けられている。第３バイパス流路１４３が、電解水生成装置１４０と第２供給流路１７１とを互いに接続する。第３開閉弁１５０ｃが、第２供給流路１７１において、第１原液タンク１７０ａ、第２原液タンク１７０ｂおよび第３バイパス流路１４３の各々との接続部より循環流路１１０側に設けられている。第４開閉弁１５０ｄが、第３バイパス流路１４３に設けられている。これにより、透析液調製装置１６０を備えて、循環流路に間接的に接続された透析装置１３０においても、透析装置１３０を洗浄する酸性電解水より次亜塩素酸の濃度が低い酸性電解水によって、逆浸透水の循環流路を洗浄可能となる。 In the dialysis machine cleaning system 100 according to the embodiment of the present invention, the dialysate preparation apparatus 160 is provided in the first supply flow path 131 on the dialysis machine 130 side with respect to the connection portion with the second bypass flow path 142. There is. The third bypass flow passage 143 connects the electrolyzed water generation device 140 and the second supply flow passage 171 to each other. The third on-off valve 150c is provided in the second supply passage 171 on the circulation passage 110 side of the connection portion with each of the first stock solution tank 170a, the second stock solution tank 170b, and the third bypass path 143. .. The fourth opening / closing valve 150d is provided in the third bypass passage 143. As a result, even in the dialyzer 130 that is equipped with the dialysate preparation device 160 and is indirectly connected to the circulation flow path, the acidic electrolyzed water having a lower concentration of hypochlorous acid than the acidic electrolyzed water for cleaning the dialyzer 130 can be used. It becomes possible to wash the circulation channel of the reverse osmosis water.
　本発明の一実施形態に係る透析装置洗浄システム１００において、中和用配管１８０は、中和用配管１８０から排出された中和用電解水が、透析装置１３０から排出された洗浄用電解水と合流するように構成されている。これにより、洗浄に用いた電解水を中和させるための中和剤が不要となり、中和剤を貯めるためのタンクを不要にできるため、透析装置洗浄システム１００を省スペース化することができる。 In the dialysis machine cleaning system 100 according to the embodiment of the present invention, the neutralization pipe 180 is configured such that the neutralized electrolyzed water discharged from the neutralization pipe 180 is the cleaning electrolyzed water discharged from the dialysis device 130. It is configured to meet. This eliminates the need for a neutralizing agent for neutralizing the electrolyzed water used for cleaning and eliminating the need for a tank for storing the neutralizing agent, thus saving space in the dialysis machine cleaning system 100.
　なお、今回開示した上記実施形態はすべての点で例示であって、限定的な解釈の根拠となるものではない。したがって、本発明の技術的範囲は、上記した実施形態のみによって解釈されるものではなく、請求の範囲の記載に基づいて画定される。また、請求の範囲と均等の意味および範囲内でのすべての変更が含まれる。 The above-described embodiments disclosed this time are exemplifications in all respects, and are not a basis for a limited interpretation. Therefore, the technical scope of the present invention should not be construed only by the embodiments described above, but should be defined based on the claims. Also, the meaning equivalent to the scope of claims and all modifications within the scope are included.
　１００　透析装置洗浄システム、１１０　循環流路、１２０　逆浸透水生成装置、１２１　原料水供給部、１３０　透析装置、１３１　第１供給流路、１３１ｘ　分岐流路、１３２　排出流路、１３９　個人用透析装置、１３９ｘ　第３供給流路、１３９ｙ　排出流路、１４０　電解水生成装置、１４１　第１バイパス流路、１４２　第２バイパス流路、１４３　第３バイパス流路、１５０ａ　第１開閉弁、１５０ｂ　第２開閉弁、１５０ｃ　第３開閉弁、１５０ｄ　第４開閉弁、１５０ｅ　第５開閉弁、１６０　透析液調製装置、１６３　排出流路、１７０ａ　第１原液タンク、１７０ｂ　第２原液タンク、１７１　第２供給流路、１７２ａ　第１原液供給流路、１７２ｂ　第２原液供給流路、１７３ａ　第１原液排出流路、１７３ｂ　第２原液排出流路、１８０　中和用配管、１８１　中和槽。 100 dialysis machine cleaning system, 110 circulation flow path, 120 reverse osmosis water generator, 121 raw water supply unit, 130 dialysis machine, 131 first supply flow path, 131x branch flow path, 132 discharge flow path, 139 personal dialysis machine 139x third supply passage, 139y discharge passage, 140 electrolyzed water generator, 141 first bypass passage, 142 second bypass passage, 143 third bypass passage, 150a first opening / closing valve, 150b second opening / closing Valve, 150c third opening / closing valve, 150d fourth opening / closing valve, 150e fifth opening / closing valve, 160 dialysate preparation device, 163 discharge flow path, 170a first stock solution tank, 170b second stock solution tank, 171, second supply path, 172a 1st undiluted solution supply flow path, 172b 2nd undiluted solution supply flow path, 173a 1st undiluted solution discharge flow path, 173b 2nd undiluted solution discharge flow path, 180 neutralization piping, 181 neutralization tank.

Claims (3)

  1. 　逆浸透水を一方向に循環させる循環流路と、
    　前記循環流路に設けられ、前記循環流路に前記逆浸透水を供給可能な逆浸透水生成装置と、
    　前記循環流路に直接的または間接的に接続された透析装置と、
    　前記循環流路と前記透析装置とを互いに接続する第１供給流路と、
    　前記循環流路を流れる前記逆浸透水を取り込んで洗浄用電解水を生成し、かつ、前記洗浄用電解水を前記第１供給流路に供給可能な電解水生成装置と、
    　前記循環流路と前記電解水生成装置とを互いに接続する第１バイパス流路と、
    　前記電解水生成装置と前記第１供給流路とを互いに接続する第２バイパス流路と、
    　前記循環流路において、前記第１バイパス流路との接続部より下流側であって、前記第１供給流路との接続部より上流側に設けられた第１開閉弁と、
    　前記第１供給流路において、前記循環流路との接続部、および、前記第２バイパス流路との接続部、の間に設けられた第２開閉弁とを備える、透析装置洗浄システム。     A circulation flow path that circulates reverse osmosis water in one direction,
    A reverse osmosis water generation device that is provided in the circulation channel and is capable of supplying the reverse osmosis water to the circulation channel,
    A dialyzer directly or indirectly connected to the circulation flow path,
    A first supply flow path connecting the circulation flow path and the dialysis device to each other;
    An electrolyzed water generation device capable of taking in the reverse osmosis water flowing through the circulation flow path to generate electrolysis water for cleaning, and supplying the electrolysis water for cleaning to the first supply flow path,
    A first bypass flow passage connecting the circulation flow passage and the electrolyzed water generating device to each other;
    A second bypass channel connecting the electrolyzed water generator and the first supply channel to each other;
    In the circulation flow path, a first opening / closing valve provided on the downstream side of the connection portion with the first bypass flow path and on the upstream side of the connection portion with the first supply flow path,
    A dialysis machine cleaning system, comprising a second opening / closing valve provided between the connection part with the circulation flow path and the connection part with the second bypass flow path in the first supply flow path.
  2. 　前記第１供給流路において、前記第２バイパス流路との接続部より透析装置側に設けられた、透析液調製装置と、
    　前記透析液調製装置に接続され、前記透析液調製装置に第１原液を供給する第１原液タンクと、
    　前記透析液調製装置に接続され、前記透析液調製装置に第２原液を供給する第２原液タンクと、
    　前記循環流路と、前記第１原液タンクおよび前記第２原液タンクの各々とを互いに接続する第２供給流路と、
    　前記電解水生成装置と前記第２供給流路とを互いに接続する第３バイパス流路と、
    　前記第２供給流路において、前記第１原液タンク、前記第２原液タンクおよび前記第３バイパス流路の各々との接続部より循環流路側に設けられた第３開閉弁と、
    　前記第３バイパス流路に設けられた第４開閉弁とをさらに備える、請求項１に記載の透析装置洗浄システム。     In the first supply flow path, a dialysate preparation device provided on the dialyzer side with respect to the connection portion with the second bypass flow path,
    A first stock solution tank connected to the dialysate preparation apparatus and supplying a first stock solution to the dialysate preparation apparatus;
    A second stock solution tank connected to the dialysate preparation apparatus and supplying a second stock solution to the dialysate preparation apparatus;
    A second supply flow path connecting the circulation flow path and each of the first stock solution tank and the second stock solution tank to each other;
    A third bypass channel connecting the electrolyzed water generator and the second supply channel to each other;
    In the second supply passage, a third opening / closing valve provided on the circulation passage side from a connection portion with each of the first stock solution tank, the second stock solution tank, and the third bypass flow path,
    The dialysis machine cleaning system according to claim 1, further comprising a fourth opening / closing valve provided in the third bypass flow path.
  3. 　前記電解水生成装置に接続され、前記電解水生成装置において生成された酸性電解水およびアルカリ性電解水のうち前記洗浄用電解水ではない方の中和用電解水を排出する中和用配管をさらに備え、
    　前記中和用配管は、該中和用配管から排出された前記中和用電解水が、前記透析装置から排出された前記洗浄用電解水と合流するように構成されている、請求項１または請求項２に記載の透析装置洗浄システム。     A neutralization pipe that is connected to the electrolyzed water generation device and discharges the neutralized electrolyzed water that is not the cleaning electrolyzed water among the acidic electrolyzed water and the alkaline electrolyzed water generated in the electrolyzed water generation device is further included. Prepare,
    The neutralization pipe is configured such that the neutralized electrolyzed water discharged from the neutralization pipe joins with the cleaning electrolyzed water discharged from the dialyzer. The dialysis machine cleaning system according to claim 2.
PCT/JP2019/045046 2018-11-21 2019-11-18 Dialysis device cleaning system WO2020105580A1 (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005034433A (en) * 2003-07-16 2005-02-10 Toray Medical Co Ltd Dialysis system and method of cleaning the same
JP2012125449A (en) * 2010-12-16 2012-07-05 Japan Organo Co Ltd Apparatus for producing dilution water for making dialysate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005034433A (en) * 2003-07-16 2005-02-10 Toray Medical Co Ltd Dialysis system and method of cleaning the same
JP2012125449A (en) * 2010-12-16 2012-07-05 Japan Organo Co Ltd Apparatus for producing dilution water for making dialysate

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