WO2020094490A1 - Compositions anti-sudorales et méthodes - Google Patents

Compositions anti-sudorales et méthodes Download PDF

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Publication number
WO2020094490A1
WO2020094490A1 PCT/EP2019/079744 EP2019079744W WO2020094490A1 WO 2020094490 A1 WO2020094490 A1 WO 2020094490A1 EP 2019079744 W EP2019079744 W EP 2019079744W WO 2020094490 A1 WO2020094490 A1 WO 2020094490A1
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WO
WIPO (PCT)
Prior art keywords
silicone
composition
antiperspirant
film
volatile solvent
Prior art date
Application number
PCT/EP2019/079744
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English (en)
Inventor
David Thomas BELL
Donna Maria COLLINS
Martin Peter Cropper
Louise Ombler MCMASTER
George Patrick MULKERRIN
Marc EEMAN
Céline LÉVÉNEZ-BOUGARAN
Original Assignee
Unilever Plc
Unilever N.V.
Conopco, Inc., D/B/A Unilever
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Unilever Plc, Unilever N.V., Conopco, Inc., D/B/A Unilever filed Critical Unilever Plc
Publication of WO2020094490A1 publication Critical patent/WO2020094490A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • A61K8/585—Organosilicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients

Definitions

  • the present invention is in the field of antiperspirant compositions and cosmetic use of an organosiloxane, film-forming polymer to treat human perspiration.
  • aluminium and/or zirconium salts have been used as antiperspirant agents.
  • a standard level of aluminium and/or zirconium salt in an antiperspirant composition is about 2-5 wt%.
  • Some antiperspirant effect can be reached by including as low as 1 wt% aluminium and/or zirconium salt.
  • there are concerns with such salts For example, frequently repeated use may be required, especially in the case of successive washing or heavy perspiration. Further, those salts may leave marks during application to the skin, which may consequently stain the underarm area of clothing as well. Therefore, there remains a desire to find alternative antiperspirant actives, to replace the aluminium and/or zirconium salts.
  • Polymers capable of forming films on hair and skin are known to the cosmetic industry, in particular the use of such polymers with solvent to enhance the efficacy of cosmetic agents.
  • JP2016084292A2 discloses a deodorant composition which has volatile component, film-forming component, a single-use amount of antiperspirant component and/or bactericidal component.
  • US2013272995A discloses a cosmetic product containing a film-forming polymer having a polyacrylamide skeleton.
  • the polymer has good compatibility with a variety of oils, especially silicone oils, readily spreads on skin and hair without sticky feeling, and forms a film having excellent water resistance, oil resistance and film properties.
  • WO2013/131 107A1 discloses a composition containing polymeric microparticles, which is effective in reducing perspiration in the absence of aluminium /zirconium antiperspirant compounds.
  • the composition may optionally comprise film-forming polymers and volatile silicone as a carrier.
  • W02013/003459A2 discloses a transfer-resistant cosmetic composition
  • a transfer-resistant cosmetic composition comprising at least one silicone film forming polymer derived from acrylic acid, at least one naturally derived volatile solvent and a cosmetically acceptable carrier.
  • EP2444062A2 discloses a cosmetic product containing film-forming polymer composed of building blocks with cycloolefin skeletons. Said polymer has good compatibility with a variety of oils, especially silicone oil, readily spreads on the skin and hair without sticky feeling and prevents the cosmetic product from staining clothes.
  • W02005/051337 discloses anhydrous antiperspirant compositions characterized by a skin-adhering polymer, one or more volatile solvents, antiperspirant active, thickening agent and an anhydrous carrier.
  • GB2407496A discloses a method of forming a film on biological surface comprising mixing an alkylene trialkoxysilyl terminated polysiloxane, an alkoxysilane, a catalyst a filler and a volatile diluent to form a formulation.
  • an organosiloxane, film-forming polymer can be used as an antiperspirant agent and such polymer can be delivered from a cosmetic composition comprising solvent of certain volatility.
  • Another objective of the present invention is to provide an antiperspirant agent which can optionally prevent, control or reduce body malodour.
  • a further objective of the present invention is to provide an antiperspirant agent which does not produce significant marks on skins and/or stains on clothing.
  • Another further objective of the present invention is to provide an antiperspirant agent which can also deliver good sensory benefits.
  • Yet another further objective of the present invention is to provide an antiperspirant agent which can be incorporated into an antiperspirant composition without compromising the stability of said composition.
  • antiperspirant agent should be understood to mean a substance that by itself has the effect of reducing or limiting human perspiration.
  • Antiperspirant benefit should be understood to mean the same as ‘antiperspirant effect’, which is preventing, controlling, reducing or limiting human perspiration.
  • sensor should be understood to mean a physical condition perceived by consumers, e.g. skin irritation, skin roughness and dryness.
  • a method of delivering an antiperspirant benefit comprising applying to human skin a cosmetic composition comprising: an organosiloxane film-forming polymer as an anti-perspirant agent, wherein the polymer is applied from the cosmetic composition comprising said polymer and a volatile solvent; and the volatile solvent being capable of evaporation to an extent from 80 to 100% by weight within 120 minutes, measured in accordance with DIN 53249 at 25°C.
  • an antiperspirant composition comprising a film-forming polymer and a volatile solvent as described in the first aspect of the invention, wherein the composition is free from aluminium and/or zirconium salt.
  • Free from aluminium and/or zirconium salt’ or‘in absence of aluminium and/or zirconium salt’ refers to a composition containing less than 1 % by weight of, preferably less than 0.1 % by weight, preferably less than 0.09% by weight of and more preferably containing zero percent by weight of aluminium and/or zirconium salt.
  • ‘Film-forming polymer’ should be understood to mean a polymer that is capable of forming a solid film that adheres to a substrate, such as human skin.
  • any feature of one aspect of the present invention may be utilised in any other aspect of the invention. Any feature described as ‘preferred’ should be understood to be particularly preferred in combination with a further preferred feature or features. Herein, any feature of a particular embodiment may be utilized in any other embodiment of the invention.
  • the word ‘comprising’ is intended to mean ‘including’ but not necessarily ‘consisting of or‘composed of. In other words, the listed steps or options need not be exhaustive.
  • the examples given in the description below are intended to clarify the invention but not to limit the invention. All percentages are weight/weight percentages unless otherwise indicated.
  • organosiloxane polymers are silicone resins, silicone gums, silicone resin/silicone fluid copolymers, silicone waxes, silicone polyamides, silicone acrylate copolymers, or mixtures thereof, preferably silicone resins, silicone gums, silicone resin/silicone fluid copolymers, silicone acrylates, or mixtures thereof, more preferably silicone resins, silicone acrylates, or mixtures thereof, and most preferably silicone resins.
  • the film-forming polymer is typically present in a concentration of 0.1-40% by weight of the total composition excluding any propellant that may be present, preferably from 1 to 35 wt%, more preferably from 5 to 35 wt%. If no propellant is employed in the composition, the preferred level of the film-forming polymer is from 0.1 to 30 wt%, more preferably from 1 to 20 wt%, most preferably from 5 to 15% by weight of the total composition.
  • Silicone resins are suitable for the present invention.
  • Siliconone resins can also be called‘siloxane resins’.
  • the nomenclature of silicone resins is known under the name‘MDTQ’, the resin being described as a function of the various siloxane monomer units it comprises, each of the letters characterizing a type of unit.
  • silicone resin refers to a compound with three-dimensional structure and comprising at least 30% T and Q siloxane bonds by total mole of all silicone atoms presented in the resin.
  • a polydimethysiloxane (PDMS) is not a silicone resin.
  • Preferred silicone resins are MQ types having the general formula:
  • Silsesquioxane resins are homo-polymers and/or co-polymers having an average siloxane unit of formula: RSlO(4-n)/2 wherein R is a hydrogen atom, or C1 -10 alkyl group and n is 1.
  • R is a C1 -C6 alkyl group and more preferably, R is a propyl group.
  • Silicone gums such as dimethiconol and silicone resin/silicone fluid copolymers such as trimethylsiloxysilicate/dimethiconol crosspolymer are also suitable for the present invention.
  • the preferred silicone resins are MQ resins, MQ resin/silicone fluid copolymers, and combinations of MQ and T Propyl resins, more preferably are MQ resins and combinations of MQ and T Propyl resins.
  • the preferred organosiloxane, film- forming polymers are resins such as trimethylsiloxysilicate, trimethylsiloxysilicate/dimethiconol crosspolymer, polypropylsilsesquioxane, or mixtures thereof. More preferably, the polymers are resins such as trimethylsiloxysilicate, polypropysilsesquioxane, or mixtures thereof.
  • the polymers as described are available from Dow Chemical ® under the trade names MQ-1600 and MQ-1640.
  • silicone acrylate copolymers are also suitable as film-forming polymers.
  • the polymers include graft or block copolymers comprised of silicone moieties of the formula R 4 R 5 R 6 S1-O- and C1 -12 alkyl acrylate or methacrylate, wherein R 4 , R 5 , R 6 are each independently a C1 -10 straight or branched chain alkyl or phenyl.
  • R 4 , R 5 , R6 are methyl groups.
  • the acrylate can be optionally substituted with one or more groups such as halogen or hydroxy.
  • Most preferred silicone acrylate copolymer is
  • (meth)acrylates/polytrimethylsiloxy(meth)acrylate copolymer The copolymer as described is available from Dow Chemical ® under the trade names FA 4002 ID Silicone Acrylate or FA 4001 CM Silicone Acrylate.
  • the preferred organosiloxane film-forming polymers are MQ resins, a combination of MQ and T Propyl resins, MQ resin/silicone fluid copolymers, silicone gums, silicone acrylate polymers, or mixtures thereof, preferably MQ resins, a combination of MQ and T Propyl resins, MQ resin/silicone fluid copolymers, silicone acrylate polymers, or mixtures thereof, more preferably MQ resins, a combination of MQ and T Propyl resins, silicone acrylate polymers, or mixtures thereof, still more preferably MQ resins, a combination of MQ and T Propyl resins, or mixtures thereof, most preferably MQ resins.
  • the polymers are trimethylsiloxysilicates, polypropylsilsesquioxanes,dimethiconol, trimethylsiloxysilicate/dimethiconol crosspolymer
  • (meth)acrylates/polytrimethylsiloxy(meth)acrylate copolymers or mixtures thereof still more preferably trimethylsiloxysilicates, polypropylsilsesquioxanes, (meth)acrylates/polytrimethylsiloxy(meth)acrylate copolymers or mixtures thereof, even more preferably trimethylsiloxysilicates, polypropylsilsesquioxanes or mixtures thereof, and most preferably trimethylsiloxysilicates.
  • the level of above-mentioned preferred polymers in an antiperspirant composition is typically from 5 to 35 wt%, excluding any propellant that may be present and if no propellant is present, it is from 5 to 15 wt%.
  • volatile solvent is an essential feature of the present invention.
  • volatile is meant a solvent which is capable of evaporation to an extent from 80 to 100% by weight of the solvent within 120 minutes, measured in accordance with DIN 53249 at 25°C.
  • the evaporation is to an extent from 95 to 100% by weight within 60 minutes, more preferably from 95 to 100% by weight within 20 minutes, most preferably 100% by weight within 10 minutes.
  • the rates of evaporation are measured in accordance with DIN 53249 at 25°C by: 1. weighing round filter paper of diameter 150mm, 2. applying a 0.3ml sample using a pipette, and immediately weighing the filter, and 3. weighing the filter at 5-minute interval at 25°C in a draught-free place. In each case amounts are weighed to an accuracy of 0.001 g.
  • the viscosity of the volatile solvent is typically from 0.65 to 1 .5 mm 2 /s, preferably from 0.65 to 1 .0 mm 2 /s, more preferably 0.65 mm 2 /s.
  • the viscosity is the kinetic viscosity measured at 25°C by employing the standard test method ASTM D445, Revision 17A, published by ASTM International (ASTM) on May 1 st , 2017. A mixture of the volatile solvent is also possible.
  • the key is the final viscosity of the mixture should not be over 1.5 mm 2 /s, preferably not over 1.0 mm 2 /s and at least 0.65 mm 2 /s, for example, a mixture of volatile solvent having viscosity of 0.65 mm 2 /s.
  • the volatile solvent is typically present in a concentration of 20-99.8% by weight of the total composition excluding any propellant that may be present, preferably from 20 to 95 wt%, more preferably from 50 to 80 wt%. If no propellant is employed in an antiperspirant composition, the preferred level of the volatile solvent is from 65 to 99.8%, more preferably from 65 to 95% by weight of the total composition.
  • the volatile solvent in the present invention is a liquid at 20°C at atmospheric pressure.
  • the film-forming polymer is preferably soluble in the volatile solvent.
  • soluble is meant having a solubility of at least 0.1g/100ml at 20°C, preferably at least 1 g/100ml, more preferably at least 10g/100ml, even more preferably at least 20g/100ml, most preferably at least 40g/100ml.
  • the weight ratio of the film-forming polymer to the volatile solvent is typically at least 1/200, preferably at least 1/100, more preferably at least 1/10, but not more than 5/2, preferably not more than 3/2, more preferably not more 1/1 .
  • the preferred volatile solvents are volatile silicones.
  • Linear volatile silicones are preferred to cyclic volatile silicones.
  • the linear silicones usually have the formula (I)
  • the average value of n is from 0 to 3.
  • the volatile silicones have the formula (II):
  • the volatile solvent as described is available from Dow Chemical ® under the trade name XIAMETER ® PMX-200 silicone fluids. Such volatile silicone is at least 50 wt%, preferably at least 75 wt%, more preferably 100% by weight of the total volatile solvent. Also the total level of the volatile solvent in the antiperspirant composition is from 20 to 99.8% by weight of the total composition excluding any propellant that may be present, preferably from 20 to 95 wt%, more preferably from 50 to 80 wt%. If no propellant is employed in an antiperspirant composition, the preferred level of the volatile solvent is from 65 to 99.8%, more preferably from 65 to 90% by weight of the total composition.
  • the organosiloxane, film-forming polymers are MQ resins, a combination of MQ and T Propyl resins, silicone acrylate polymers, or mixtures thereof, preferably the MQ resins, a combination of MQ and T Propyl resins, or mixtures thereof.
  • the polymers are trimethylsiloxysilicates, polypropylsilsesquioxanes, (meth)acrylates/polytrimethylsiloxy(meth)acrylate copolymers, or mixtures thereof, even more preferably trimethylsiloxysilicates, polypropylsilsesquioxanes, or mixtures thereof.
  • Such polymer is applied from a composition comprising said polymer and volatile silicone having formula (II).
  • the silicone is disiloxane, trisiloxane, tetrasiloxane, or mixtures thereof, more preferably disiloxane, trisiloxane, or mixtures thereof and most preferably disiloxane.
  • the levels of such preferred polymer and preferred volatile solvent are from 5 to 35% and 20 to 95% respectively, by weight of the total composition excluding any propellant that may be present.
  • the weight ratio of such preferred polymer to such preferred volatile solvent is from 1 :200 to 5:2, preferably from 1 :100 to 1 :1 .
  • the film-forming polymers are MQ resins, a combination of MQ and T Propyl resins, silicone acrylate polymers, or mixtures thereof, preferably the MQ resins, a combination of MQ and T Propyl resins, or mixtures thereof.
  • the polymers are trimethylsiloxysilicates, polypropylsilsesquioxanes,
  • Such polymer is applied from a composition comprising said polymer and a mixture of volatile silicones having formula (II). It is advantageous to use a mixture of volatile silicones for the improvement of sensory and/or ease of manufacturing. The mixture of volatile silicones also helps to achieve an optimal balance of antiperspirant benefit from the film-forming polymer and the processing of said polymer.
  • the levels of preferred polymer and total mixture of silicones are from 5 to 35% and 20 to 95% respectively, by weight of the total composition excluding any propellant that may be present; the weight ratio of the polymer to mixture of volatile silicones is from 1 :100 to 1 :1.
  • the antiperspirant composition of the present invention comprises a film-forming polymer and a volatile solvent, both as described in the first aspect of the invention.
  • the composition is free from any aluminium and/or zirconium salt.
  • the composition is anhydrous.
  • anhydrous refers to compositions that contain less than 1 % by weight of added water or free water, preferably less than 0.5wt %, more preferably less than 0.1 wt % and most preferably 0 wt%, with respect to the total weight of the composition.
  • the antiperspirant composition does not need to contain additional cosmetically acceptable carrier, other than the volatile solvent.
  • Cosmetically acceptable carrier or ‘carrier’ should be understood to mean a substance that is compatible with the skin and/or its integuments or mucous membranes, not causing any unacceptable discomfort liable to discourage the consumer from using and preferably, having pleasant colour, odour and/or feel.
  • additional carriers such as hydrocarbon oils, ester oils, ether oils and alcohol oils, or mixtures thereof can be used.
  • a preferred class of suitable carrier is an oil.
  • oil used herein refers to an organic material that is liquid and has solubility of less than 0.1 g/100ml in water at 20°C.
  • a preferred class can be non-volatile silicone oils such as Cyclopentasiloxane (and) Dimethiconol, available as Dow Chemical ® 1501 fluid.
  • composition according to the present invention is preferably in a single, homogeneous phase.
  • the film-forming polymers are typically soluble in the volatile solvents; and both the polymers and volatile solvents are typically soluble in any carrier and/or propellant employed.
  • single phase is meant that the composition does not form two or more distinct separate phases (liquid or solid) at 20°C.
  • the meaning of ‘soluble’ can be referred to its aforementioned definition in section of‘volatile solvent’.
  • the cosmetically acceptable carrier is typically employed at a level of no more than 50 wt% of the total composition excluding any propellant that may be present, preferably no more than 30 wt%, more preferably no more than 20 wt% and most preferably no more than 10 wt%.
  • the ethanol content of the composition is kept to a minimum, by which is meant the ethanol is no more than 10%, preferably no more than 5%, more preferably no more than 1 %, still more preferably no more than 0.1 %, most preferably 0% by weight of the total composition.
  • the ethanol content may be from 10% by weight to 35% by weight, preferably 10% by weight to 30% by weight of the total composition excluding any propellant.
  • Such embodiments may enjoy various benefits, such as not affecting the film formation or permeation, potentially providing a higher sweat reduction than similar compositions containing lower levels of ethanol and providing a cheaper solvent composition without compromising sensory properties of the composition.
  • compositions according to present invention may desirably contain a fragrance.
  • suitable materials include conventional perfumes, such as perfume oils and also include so-called deo-perfumes, as described in EP 545,556, for example.
  • the fragrance may comprise a single fragrance or component more commonly a plurality of fragrance components. Levels of incorporation are preferably up to 5% by weight, particularly from 0.1 % to 3.5% by weight, and especially from 0.5% to 2.5% by weight of the total composition.
  • the present invention is preferably free from encapsulated fragrance. ‘Encapsulated fragrance’ should be understood to mean a fragrance encapsulated in one of the multiple encapsulating materials used for this purpose.
  • ‘Free from’ used herein should be understood to mean the level of encapsulated fragrance in the composition is less than 0.1wt%, preferably less than 0.01 wt%, more preferably 0 wt%.
  • Anti-microbial agent is another preferred feature in the antiperspirant composition. When employed, the level of the incorporation is typically at least 0.01 %, preferably 0.03%, but not more than 5%, preferably not more than 2%, more preferably not more than 1 % by weight of the total composition.
  • Preferred anti-microbial agents are those that are more efficacious than simple alcohols such as ethanol.
  • Examples include niacinamide; quaternary ammonium compounds, like cetyltrimethylammonium salts; chlorhexidine and salts thereof; and diglycerol monocaprate, diglycerol monolaurate, glycerol monolaurate, and similar materials, as described in“Deodorant Ingredients”, S.A.Makin and M.R. Lowry, in “Antiperspirants and Deodorants”, Ed. K. Laden (1999, Marcel Dekker, New York).
  • polyhexamethylene biguanide salts also known as polyaminopropyl biguanide salts
  • an example being Cosmocil CQ available from Arch Chemicals, 2', 4, 4'-trichloro, 2-hydroxy-diphenyl ether (triclosan), 3,7,1 1 -trimethyldodeca- 2,6, 10-trienol (farnesol), essential oils such as Tea Tree Oil and Thyme Oil, climbazole, octapyrox, ketoconazole, zinc pyrithione and mixtures thereof.
  • deodorant agent refers to an agent capable of treating the body odour by controlling, suppressing, reducing, or preventing the formation of unpleasant odours on the surface of the human body, preferably in the underarm areas.
  • the fragrance and anti-microbial agents employed are typically soluble in a mixture of film-forming polymer, volatile solvents and any cosmetically acceptable carrier and/or propellant that may be present.
  • antiperspirant agents may also be included. Those may be routinely chosen by the person skilled in the art and the chosen ones may also have anti-microbial efficacy.
  • the preferred agents include but not limited to chitosan, chitosan derivatives, chitosan salts, or mixtures thereof.
  • Other suitable antiperspirant agents may be chosen from water-dispersible thiolated polymers according to US 2009/0016978A1 , non-pore blocking antiperspirant agents according to WO 2016/066518 selected from 6-gingerol, 6-gingerdiol, or ethyl cinnamate, etc.
  • the key is the antiperspirant or the anti-microbial agents chosen are free from aluminium and/or zirconium salts.
  • Another preferred component is a preservative, such as ethyl or methyl parabens or BHT (butyl hydroxy toluene), typically in an amount of from 0.01 to 0.1 % by weight of the total composition.
  • the antiperspirant compositions of the present invention may be in the form of roll-ons, sprays, or aerosols, preferably pump sprays or aerosols.
  • a propellant which is typically either a compressed gas or a liquefied propellant gas.
  • compressed gas include nitrogen (N 2 ) and air.
  • Preferred liquefied propellant gases are hydrocarbons or halogenated hydrocarbon gases (particularly fluorinated hydrocarbons such as 1 ,1-difluoroethane and/or 1- trifluoro-2-fluoroethane) that have a boiling point of below 10°C and especially those with a boiling point below 0°C.
  • DME dimethyl ether
  • liquefied hydrocarbon gases for instance, C3 to C6 hydrocarbons, including propane, butane, isobutane, pentane and isopentane and mixtures of two or more thereof.
  • propane, butane, isobutane, pentane and isopentane and mixtures of two or more thereof are especially preferred.
  • the level of the liquefied propellant gas in an aerosol composition is typically from 30 to 99% by weight, preferably from 40 to 95% by weight and even more preferably from 50 to 90% by weight of the total composition.
  • Antiperspirant products in accordance with the present invention comprise an antiperspirant composition as described in the third aspect of the present invention and a dispenser wherein said composition is housed.
  • a suitable dispenser for an aerosol composition typically comprises a can, usually made from steel or aluminium, often having a coated interior to prevent contact between the can contents and the can wall, which the content can be vented to the exterior through a dip tube leading via a valve that is openable and closable by an actuator, into a spray channel terminating in a spray nozzle.
  • Suitable dispensers are described, for example in EP1219547, EP1255682, or EP1749759.
  • Aerosol products can be made in a conventional manner by first preparing a base composition, charging the composition into the aerosol can, fitting a valve assembly into the mouth of the can, thereby sealing the latter, and thereafter charging the propellant into the can to a desired pressure, and finally fitting an actuator on or over the valve assembly together.
  • the compressed gas such as nitrogen or air is charged into the can containing a base composition, to a desired pressure of 2-10 bar, preferably 2-8 bar.
  • a suitable dispenser for a spray composition typically comprises a canister, a valve, and a nozzle.
  • the device comprises a means for enhancing the atomisation of the spray, for example a mechanical break up unit such as a swirl chamber.
  • the canister can be made from thermoplastic polymers or can be a pressure canister made from metal, for example tinplate, or preferably, aluminium.
  • Metal canisters are preferably lacquered on their inside, for example with an epoxyphenolic resin or, more preferably, with polyamide imide resin.
  • the spray device is capable of containing and dispensing a composition at a pressure of from 398 to 487 kPa at 21 °C and generating a spray of D[4,3] droplet size of from 10 to 50 pm at 21 °C.
  • a suitable spray device is described in WO 2005/123025.
  • Other suitable spray devices include but are not limited to devices for trigger spray, pump spray and squeeze spray.
  • a suitable dispenser for a roll-on composition typically comprises a bottle having a mouth at one end defining a retaining housing for a rotatable member, commonly a spherical ball or less commonly a cylinder which protrudes above the top wall of the bottle.
  • Suitable applicators are described for example in EP1 175165, or W02006/007987.
  • the bottle mouth is typically covered by a cap, typically having a screw thread that cooperates with a thread on the housing or in an innovative design by a plurality of staggered bayonet/lug combinations.
  • Suitable material for making roll-on dispensers includes thermoplastic polymers.
  • the antiperspirant compositions of the present invention may be topically applied to underarm area of human skin in an amount effective to reduce or inhibit perspiration.
  • the composition is applied in an amount of at least 0.1 g to no more than 20g, preferably from 0.5 g to no more than 10g, more preferably from 1 g to no more than 5g.
  • the composition is typically applied once or twice per day.
  • the composition can also be applied once per every other day or once per every third or fourth day to achieve the antiperspirant efficacy over an extended period.
  • the composition can be preferably sprayed onto the underarm skin, wherein the volatile solvent evaporates and leaves behind a polymer film that can inhibit sweating.
  • the composition may be applied by any suitable means.
  • application of a liquid composition may be by adsorption onto a carrier matrix like paper, fabric, or sponge and application by contacting said carrier matrix with the human skin.
  • Application may also comprise a combination of any two or more of the above techniques.
  • antiperspirant compositions of the present invention may be prepared by any known or otherwise effective techniques, especially suitable for providing an anhydrous composition in aerosol form and having the essential features of film-forming polymers and volatile solvents described herein.
  • An example of manufacturing process may include steps as such: A film-forming polymer supplied either as a solid or in solution is added at the required level to the solvent or volatile solvent. The mixture is stirred at ambience until the polymer is fully solubilised. Preferably, the mixing is undertaken in an enclosed vessel. Any additional components such as fragrance, antimicrobials and/or cosmetically acceptable carriers can then be added with further mixing until a solution with homogeneity is obtained. The solution is then filled into the dispenser of choice. If an aerosol is manufactured, the solution is charged into an aerosol can, fitting a valve assembly into the mouth of the can and thereafter the propellant is charged into the can to a desired pressure. Finally, an actuator is fitted on or over the valve assembly together.
  • the present invention may be illustrated by the following non-limiting examples.
  • Example 1 The following antiperspirant formulations (Example 1 to Example 27) are according to the present invention.
  • a typical base formulation of a compressed gas aerosol is given in Table 4.
  • the base formulation can be formed by any technique known in the art or the manufacturing process given in the present invention as an example.
  • 70-110g of the base formulation is charged into a can sized 150ml.
  • Nitrogen gas (N 2 ) is applied to the can until the pressure is around 7bar.
  • a the viscosity of the blend PMX-200 is 3.6cSt
  • the panellists underwent a 17- day pre-test phase, during which they used only an alcoholic deodorant product in their underarms. During the test phase, the panellists attended the test centre. They washed and dried their underarms. A test product and a control product without any antiperspirant active were applied (one to each underarm) at the same dosage, by the test centre staffs.
  • the panellists entered a hot room set at 40°C and 40% relative humidity, approximately 1 hour after the product application. The panellists sat in the hot room for a 40-minute or 20-minute warm-up period. Then their underarms were dried and pre-weighed absorbent cotton pads were placed in each underarm. After a further 20-minute sitting, the cotton pads were collected and re-weighed.
  • the sweat reduction (SWR) from each test product was calculated according to the difference of the weight recorded, in comparison to the control product.
  • Examples A, B, C and D have the solvent not according to the present invention.
  • Examples 29 and 30 have the solvent according to the present invention. Examples 29 and 30 showed significant improvement in sweat reduction whilst no improvement was observed for Examples A-D.

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  • Cosmetics (AREA)

Abstract

La présente invention concerne une méthode qui permet de fournir un avantage anti-sudoral, la méthode comprenant l'application sur la peau humaine d'une composition cosmétique comportant un polymère filmogène d'organosiloxane en tant qu'agent anti-sudoral, le polymère appliqué provenant de la composition cosmétique comprenant ledit polymère et un solvant volatil, le solvant volatil étant capable de s'évaporer jusqu'à perdre de 80 à 100 % en poids dans les 120 minutes, tel que mesuré selon la norme DIN 53249 à 25 °C. L'invention concerne également une composition cosmétique comportant le polymère et le solvant volatil, et étant exempte de sel d'aluminium et/ou de zirconium.
PCT/EP2019/079744 2018-11-08 2019-10-30 Compositions anti-sudorales et méthodes WO2020094490A1 (fr)

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EP1175165A1 (fr) 1999-04-23 2002-01-30 Unilever Plc Emballage destine a la distribution d'une composition cosmetique fluide et produit correspondant
EP1255682A1 (fr) 2000-02-14 2002-11-13 Unilever Plc Mecanisme d'actionnement
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EP1749759A1 (fr) 2005-08-05 2007-02-07 Unilever Plc Bouchon distributeur pour dispositif de pulvérisation
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WO2013003459A2 (fr) 2011-06-30 2013-01-03 Elc Management Llc Composition cosmétique résistant au transfert
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