WO2020009351A1 - Pointe d'injection de médicament, pièce à main et dispositif de traitement de la peau - Google Patents

Pointe d'injection de médicament, pièce à main et dispositif de traitement de la peau Download PDF

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Publication number
WO2020009351A1
WO2020009351A1 PCT/KR2019/007319 KR2019007319W WO2020009351A1 WO 2020009351 A1 WO2020009351 A1 WO 2020009351A1 KR 2019007319 W KR2019007319 W KR 2019007319W WO 2020009351 A1 WO2020009351 A1 WO 2020009351A1
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WO
WIPO (PCT)
Prior art keywords
space
plunger
cylinder
skin
tip
Prior art date
Application number
PCT/KR2019/007319
Other languages
English (en)
Korean (ko)
Inventor
안경호
Original Assignee
주식회사 제이시스메디칼
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020180154688A external-priority patent/KR102062219B1/ko
Application filed by 주식회사 제이시스메디칼 filed Critical 주식회사 제이시스메디칼
Priority to EP19829896.0A priority Critical patent/EP3819004B1/fr
Priority to JP2020573399A priority patent/JP7244115B2/ja
Priority to EP22201267.6A priority patent/EP4137197B1/fr
Priority to EP24164484.8A priority patent/EP4364769A2/fr
Priority to CN201980042717.3A priority patent/CN112368046A/zh
Priority to US16/697,163 priority patent/US11376374B2/en
Publication of WO2020009351A1 publication Critical patent/WO2020009351A1/fr
Priority to IL279842A priority patent/IL279842A/en
Priority to US17/826,737 priority patent/US20220288327A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/328—Applying electric currents by contact electrodes alternating or intermittent currents for improving the appearance of the skin, e.g. facial toning or wrinkle treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/06—Electrodes for high-frequency therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452—Skin
    • A61B2018/0047—Upper parts of the skin, e.g. skin peeling or treatment of wrinkles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A61B2018/143—Needle multiple needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0502—Skin piercing electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/322—Electromedical brushes, combs, massage devices

Definitions

  • the present invention relates to a drug application tip, a hand piece and a skin treatment device for invading a needle to a predetermined depth in a deep portion of a skin by a pumping effect and injecting a drug into an inside of an invasive site.
  • the skin treatment device can treat the subject's skin by repeatedly invading the plurality of needles into the skin to remove malignant tissue and form new tissue.
  • a high frequency is applied to the plurality of needles (however, various types of electric energy may be applied without being limited to the high frequency; in this case, the plurality of needles may be referred to as a plurality of RF needle electrodes). May be
  • the device of the method of transmitting high frequency to the skin tissue uses a hand piece provided with a single or a plurality of radio frequency (RF) needle electrodes, and the RF needle electrode is placed at the deep portion of the skin of the target point (for example, the face). It invades the dermal layer and uses heat generated by high frequency to remove damaged collagen, elastic fibers, etc. from the deepest part of the skin at the target site and promote new formation. Furthermore, these skin treatment devices improve the pigmentation of the skin, acne marks and wrinkles.
  • RF radio frequency
  • the surface of the skin of the target site is formed by the curvature and wrinkles formed by the pressure during the procedure, there is a problem that a plurality of needles can not invade to a uniform depth. That is, some of the plurality of needles do not reach the deep portion of the skin at the target point, which causes a decrease in skin regeneration efficiency.
  • a drug is applied to alleviate the pain caused when the plurality of needles invade deep into the skin and to treat the minute wound.
  • the general skin treatment device in order to improve the efficacy of the drug it is effective to inject the drug deep into the invasion site, the general skin treatment device has a problem that can not inject the drug deep into the invasion site.
  • the problem to be solved by the present invention is to infiltrate the needle to the depth of the skin to a predetermined depth while at the same time drug injection tips for injecting drugs through the holes of the skin formed by the needle, the handpiece and the tip is mounted It is to provide a skin treatment apparatus using.
  • Drug injection tip for solving the above problems is a cylinder; A plunger reciprocating downwardly and upwardly to form a first space and a second space inside the cylinder; A needle disposed in the plunger, the needle disposed in the second space of the cylinder, the needle is inserted into the skin when the plunger moves downward, and a negative pressure state is formed in the second space, and when the plunger moves upward, The needle may be discharged from the skin and a positive pressure state may be formed in the second space.
  • a hole is formed in the skin by insertion and discharge of the needle, and the drug may be injected into the hole formed in the skin in a positive pressure state of the second space.
  • the surface of the skin may be pierced into the second space by the negative pressure state of the second space, and the needle may invade to a predetermined depth.
  • a first channel connecting the first space and the second space may be formed in the drug injection tip.
  • the first channel may be at least one of a flow path formed in the plunger, a gap between the cylinder and the plunger, and a tube connecting the first space and the second space.
  • the amount of change in the volume of the first space due to the reciprocating movement of the plunger is greater than the amount of change in the volume of the second space, so that the gas in the second space is moved through the first channel through the first channel when the plunger moves downward.
  • the gas of the first space may move to the second space through the first channel.
  • the cylinder may be provided with a valve connecting the outside and the first space in the open state.
  • the valve may be opened in a negative pressure state of the first space to introduce external air into the first space, and may be closed in a positive pressure state of the first space to block outflow of air in the first space to the outside.
  • the valve may be opened when the plunger moves downward, and may be closed when the plunger moves upward.
  • the cylinder includes a first cylinder and a second cylinder
  • the plunger includes a first plunger for forming the first space and an excess space in the first cylinder, and a second space for forming the second space in the second cylinder.
  • the second cylinder may include a plunger, and connects the surplus space and the outside to the first cylinder.
  • a third channel connecting the first space and the surplus space may be formed in the first plunger.
  • the cylinder may be formed with a fourth channel connecting the first space and the outside.
  • the fourth channel may be opened by the movement of the plunger when the plunger moves downward, and may be closed by the movement of the plunger when the plunger moves upward.
  • the cylinder may be formed with a fifth channel connecting the outside and the first space.
  • the fifth channel may be opened by the movement of the plunger when the plunger moves downward, and may be closed by the movement of the plunger when the plunger moves upward.
  • High frequency may be applied to the needle.
  • the high frequency applied to the needle may generate heat energy in the deep portion of the skin.
  • Hand piece according to an aspect of the present invention for solving the above problems can be equipped with the drug injection tip.
  • Skin treatment apparatus for solving the above problems can inject the drug to the deep skin of the patient using the drug injection tip.
  • the drug can be injected into the hole of the surface of the skin formed by the needle in the positive pressure state and the skin can be crushed in the negative pressure state, so that the needle can be inserted to a predetermined depth.
  • the present invention provides a hand piece to which the tip is mounted and a skin treatment apparatus using the tip.
  • FIG. 1 is a conceptual diagram illustrating the application of a high frequency using the RF needle.
  • FIG. 2 is a perspective view showing a skin treatment apparatus of the present invention.
  • FIG. 3 is a perspective view showing a hand piece of the present invention.
  • Figure 4 is a cross-sectional view of the tip for drug injection of the present invention.
  • Figure 5 is a cross-sectional view showing the pumping effect occurs by operating the tip for drug injection of the present invention.
  • FIG. 6 is a cross-sectional view showing the pumping effect is generated by the operation of the tip of the drug injection of the first modification of the present invention.
  • FIG. 7 is a cross-sectional view showing the pumping effect is generated by the operation of the tip for drug injection of the second modification of the present invention.
  • FIG. 8 is a cross-sectional view showing the pumping effect occurs by operating the tip for drug injection of the third modification of the present invention.
  • FIG. 9 is a cross-sectional view showing the pumping effect is generated by the operation of the tip of the drug injection of the fourth modification of the present invention.
  • FIG. 10 is a cross-sectional view showing the pumping effect is generated by the operation of the tip for drug injection of the fifth modification of the present invention.
  • FIG. 11 is a cross-sectional view showing a pumping effect of the drug injection tip of the present invention is increased by the groove and the sheet formed in the second cylinder.
  • FIG. 12 is a flow chart of a skin treatment method using a drug injection tip of the present invention.
  • spatially relative terms below “, “ beneath “, “ lower”, “ above “, “ upper” It can be used to easily describe a component's correlation with other components. Spatially relative terms are to be understood as including terms in different directions of components in use or operation in addition to the directions shown in the figures. For example, when flipping a component shown in the drawing, a component described as “below” or “beneath” of another component may be placed “above” the other component. Can be. Thus, the exemplary term “below” can encompass both an orientation of above and below. Components may be oriented in other directions as well, so spatially relative terms may be interpreted according to orientation.
  • FIG. 1 is a conceptual diagram showing the application of high frequency using the RF needle
  • Figure 2 is a perspective view showing a skin treatment apparatus of the present invention
  • Figure 3 is a perspective view showing a hand piece of the present invention
  • Figure 4 is a view of the present invention
  • Figure 5 is a cross-sectional view of the tip for drug injection
  • Figure 5 is a cross-sectional view showing the pumping effect is generated by the operation of the tip of the drug injection of the present invention
  • Figure 6 is a pumping tip of the drug injection of the first modification of the present invention operates 7 is a cross-sectional view showing that the effect occurs
  • Figure 7 is a cross-sectional view showing the pumping effect is generated by the operation of the tip of the drug injection of the second modification of the present invention
  • Figure 8 is a drug injection of the third modification of the present invention
  • Figure 9 is a cross-sectional view showing that the pumping effect is generated by the operation of the tip
  • Figure 9 is a cross-sectional view showing that the pumping effect
  • the “vertical direction” may be the vertical direction shown in FIG. 4 and may be mixed with the “up and down direction”. That is, “one side in the vertical direction” may be an upper side, and the “other side in the vertical direction” may be a lower side.
  • the skin treatment apparatus 1000 of the present invention can be used for scar treatment, hair growth treatment, liquor treatment, vascular treatment, fat reduction, wrinkle removal, skin elasticity recovery, sebum removal and acne treatment.
  • the skin treatment apparatus 1000 of the present invention includes a main body 100, a display module 200, an operation module 300, an electronic control module (not shown), a cable 400, a hand piece 500, and a drug injection tip. 600, a driving module 700, and a power module (not shown) may be included.
  • the main body 100 may be provided with a display module 200 and an operation module 300.
  • the display module 200 may be manufactured in the form of a panel to visually provide various information to the doctor instructing the skin treatment procedure. Therefore, as an example, the display module 200 may graphically display the output amount or impedance of the high frequency applied to the dermal layer of the current target point.
  • the display module 200 may display a driving mode currently being performed by the skin treatment apparatus 1000 of the present invention.
  • the display module 200 may display biometric information of a deep portion of the skin tissue at the target point.
  • the operation module 300 may be provided in the form of a button on the outer surface of the main body 100.
  • the doctor may turn on / off the skin treatment apparatus 1000 through the manipulation module 300, select an operation mode of the skin treatment apparatus 1000, and change an output amount of high frequency applied to the target point.
  • the display module 200 is provided in the form of a touch screen, at least a part of the manipulation module 300 may be omitted.
  • the doctor may manipulate the skin treatment apparatus 1000 by touching a menu displayed on the screen of the display module 200.
  • the electronic control module may be embedded in the main body 100 and may electronically control the components of the skin treatment apparatus 1000. To this end, the electronic control module may be electrically connected to the driving module 700 and the power module through the cable 400. That is, the electronic control module may apply a control signal corresponding to the manipulation signal of the doctor to the driving module 700 and the power module.
  • a driving cycle of the driving module 700 may be controlled by a control signal of the electronic control module.
  • the reciprocating drive cycle of the needle unit 620 of the drug injection tip 600 can be controlled.
  • the output amount of the power supply module and the like may be controlled by the control signal of the entire control module.
  • the wavelength, direction, and intensity of the current applied to the one or more needles 621 of the needle unit 620 may be changed to control the output amount of the high frequency applied to the target point.
  • high frequency is not necessarily applied to one or more needles 621. That is, in consideration of the therapeutic purpose, effects, and economics, electrical energy may not be applied to one or more needles 621.
  • the cable 400 may perform a function such as a conductive line connecting the electronic control module and the driving module 700 or electrically connecting the electronic control module and the power module. To this end, the cable 400 may extend to one side from the main body 100 to connect the main body 100 and the hand piece 500.
  • the cable 400 may include a plurality of wires so as to form respective channels according to types of electronic signals, and the outer surface of the cable 400 may insulate and cover the wire bundles of various channels.
  • the hand piece 500 is a part held by the doctor, and the doctor may change the target point (eg, part of the face) by moving the hand piece 500 in contact with the skin of the subject.
  • Hand piece 500 may be disposed in cable 400 and may be located at an end in the direction in which cable 400 extends.
  • the hand piece 500 may include a driving module 700 and a power module. Therefore, the cable 400 may electrically connect each of the driving module 700 and the power module built in the hand piece 500 with the electronic control module built in the main body 100.
  • An end portion of the hand piece 500 may be equipped with a tip 600 for drug injection.
  • the drug injection tip 600 may be replaceably mounted at the end of the hand piece 500 in the form of a cartridge.
  • the outer side of the hand piece 500 is docked to the first conductive member 501 and the cable connector 503 for electrically connecting the needle unit 620 of the drug injection tip 600 and the power module and the power module and
  • the second conductive member 502 may be disposed to electrically connect the cable 400.
  • the first conductive member 501 and the second conductive member 502 may be manufactured in the form of a film.
  • the first conductive member 501 and the second conductive member 502 may be flexible printed circuit boards (FPCBs).
  • the needle unit 620 of the tip 600 for drug injection is reciprocated (drives), so that the conductive line does not interfere during the reciprocation of the needle unit 620 of the tip 600 for drug injection.
  • the needle unit 620 of the tip 600 and the conductive line of the power module and the conductive line of the power module and the cable 400 are provided outside the hand piece 500.
  • the drug injection tip 600 may be a member that applies high frequency to the deep skin of the target point.
  • the drug injection tip 600 may be detachably mounted at the end of the hand piece 500. That is, the drug injection tip 600 of the present invention is manufactured in the form of a cartridge, it may be replaceable.
  • the drug injection tip 600 may include a cylinder 610 and a needle unit 620.
  • the cylinder 610 may be a member detachably mounted to the end of the hand piece 500 with a "stator".
  • the needle unit 620 may invade the skin core of the target point at a certain period (drive cycle of the driving module) by including the one or more needles 621 as “operators (moving in the vertical direction)", as necessary. It may be a member that applies radio frequency (RF) to the dermal layer of the skin.
  • RF radio frequency
  • the cylinder 610 may be hollow in the vertical direction.
  • the needle unit 620 may be disposed in the inner space of the cylinder 610.
  • the lower surface of the cylinder 610 may be open, and the lower end of the cylinder 610 may be disposed on the surface of the skin at the target point.
  • the open portion of the cylinder 610 can be closed by the surface of the skin at the target point.
  • the cylinder 610 may include a first cylinder 611 and a second cylinder 612.
  • the first cylinder 611 may be located above, and the second cylinder 612 may be located below.
  • the lower end of the first cylinder 611 and the upper end of the second cylinder 612 may be connected.
  • the lower surface of the second cylinder 612 may be opened.
  • the needle unit 620 may be disposed inside the first cylinder 611 and the second cylinder 612, and the connecting portion of the first cylinder 611 and the second cylinder 612 may be connected to the needle unit 620. Can be closed by
  • the connecting rod 625 of the needle unit 620 may penetrate the upper surface of the first cylinder 611.
  • the first space 1 and the surplus space 1-1 may be formed by the first plunger 623-1 of the needle unit 620. That is, the inner space of the first cylinder 611 may be closed in the vertical direction by the first plunger 623-1 of the needle unit 620, and positioned below the first space 1 located above. It can be divided into a surplus space (1-1).
  • a gasket 626 may be disposed between the upper surface of the first cylinder 611 and the connecting rod 625 of the needle unit 620. Can be. In addition, a gasket 626 may be disposed between the inner circumferential surface of the first cylinder 611 and the outer circumferential surface of the first plunger 623-1 of the needle unit 620.
  • the lower end of the second cylinder 612 may be disposed on the surface of the skin of the target point.
  • the second cylinder 612 may have a second space 2 having a lower surface opened by the second plunger 623-2 of the needle unit 620.
  • the inner space of the second cylinder 612 may be closed in the vertical direction by the second plunger 623-2 of the needle unit 620, and the holder 622 and the needle unit of the needle unit 620 may be disposed on the upper side thereof.
  • the second plunger 623-2 of 620 may be disposed, and a second space 2 having an open lower surface thereof may be positioned below.
  • One or more grooves 612-1 may be formed on the bottom surface of the second cylinder 612 (see FIG. 3).
  • One or more grooves 612-1 of the second cylinder 612 may be formed as an inner circumferential surface of the second cylinder 612 on the outer circumferential surface of the second cylinder 612. That is, one or more grooves 612-1 of the second cylinder 612 may be formed through the second cylinder 612.
  • one or more grooves 612-1 of the second cylinder 612 may be arranged to be spaced apart from each other along the circumference of the bottom surface of the second cylinder 612. That is, one or more grooves 612-1 of the second cylinder 612 may be formed to be spaced apart from each other in the circumferential direction.
  • the open portion of the lower surface of the second space 2 may be closed by the surface of the skin of the target point.
  • a gasket 626 is disposed between the inner circumferential surface of the second cylinder 612 and the outer circumferential surface of the second plunger 623-2 of the needle unit 620.
  • the second space 2 maintains airtightness
  • only the lower end portion is selectively connected to the outside by one or more grooves 612-1 of the second cylinder 612, thereby increasing the pumping effect described later. You can.
  • One or more needles 621 of the needle unit 620 may be disposed in the second space 2. As described above, since the lower surface of the second space 2 is open, the one or more needles 621 may enter the surface of the skin of the target point through the open portion of the second space 2.
  • the cross-sectional area perpendicular to the vertical direction of the first cylinder 611 may be larger than the cross-sectional area perpendicular to the vertical direction of the second cylinder 612. Therefore, due to the reciprocating movement of the plunger 623 of the needle unit 620 in the vertical direction, the amount of change in the volume of the first space 1 of the first cylinder 611 is changed to the second space of the second cylinder 612 ( It may be larger than the volume change in 2).
  • Cylinder 610 may further include seat 613 (see FIG. 11).
  • the seat 613 may be located in the second space 2.
  • the seat 613 may be disposed to be inclined downward from the inner circumferential surface of the second cylinder 612 to the inside.
  • the seat 613 may be disposed along the inner circumferential surface of the second cylinder 612 in a ring shape.
  • the seat 613 of the present invention may be disposed along the circumference of one or more needles 621 of the needle unit 620, similar to the form of a "valve seat”. That is, the seat 613 may cover the circumference of one or more needles 621 of the needle unit 620.
  • the outer end of the sheet 613 may be a fixed end, and the inner end of the sheet 613 may be a free end. Therefore, the downward inclination angle of the seat 613 may be varied by the flow of air around the seat 613.
  • the sheet 613 may be formed of an elastic material.
  • the outer end of the seat 613 may be disposed above the one or more grooves 612-1 of the second cylinder 612. As a result, the inclination angle of the seat 613 may vary depending on the flow of air flowing through the one or more grooves 612-1 of the second cylinder 612.
  • the seat 613 may interact with one or more grooves 612-1 of the second cylinder 612 to increase the pumping effect described below.
  • the needle unit 620 may be disposed in the cylinder 610.
  • the needle unit 620 may reciprocate in the vertical direction by the driving module 700. That is, the needle unit 620 may be disposed inside the first cylinder 611 and the second cylinder 612, and may reciprocate like a "piston".
  • the plunger 623 may be provided to partition the internal space of the first cylinder 611 and the second cylinder 612, and the volume of the internal space of the first cylinder 611 and the second cylinder 612 may be defined. Can change.
  • the needle unit 620 may repeatedly invade the skin at the target point by reciprocating movement in the vertical direction. Furthermore, the needle unit 620 may generate a high frequency at the deep portion of the skin of the target point, and collagen and elastic fibers, etc. damaged by the heat energy due to the high frequency may be regenerated over time, thereby increasing skin elasticity.
  • the needle unit 620 may include one or more needles 621, a holder 622, a plunger 623 and a connecting rod 625.
  • One or more needles 621 may reciprocate with the plunger 623 to alternately repeat insertion and discharge into the skin. High frequency may be applied to the one or more needles 621 to generate heat energy in the deep portion of the skin at the target point.
  • the present invention is not limited thereto, and electrical energy and ultrasonic waves of various wavelength bands may be applied to one or more needles 621. Furthermore, as described above, electrical energy, ultrasonic waves, or the like may not be applied to the one or more needles 621.
  • the power When electrical energy such as high frequency is applied to the one or more needles 621, the power may be electrically connected to the power module.
  • the one or more needles 621 may be electrically connected to the power supply module by the first conductive member 501 described above.
  • the one or more needles 621 may be a bipolar type electrode unit in which a plurality of electrodes have two polarities and a high frequency is generated between neighboring electrodes, and all of the plurality of electrodes have the same polarity. It may also be a monopolar type electrode unit. On the other hand, when the one or more needles 621 is a monopolar type, a ground electrode module (not shown) for refluxing the high frequency generated from the one or more needles 621 may be further provided.
  • One or more needles 621 may be supported by the holder 622. One or more needles 621 may extend down in the holder 622. One or more needles 621 may be disposed in the second space 2 of the second cylinder 612.
  • One or more needles 621 may reciprocate in the vertical direction by the driving force of the driving module 700.
  • the lower end of the one or more needles 621 at the bottom dead center of the needle unit 620 may be disposed at the skin core of the target point, and the lower end of the one or more needles 621 at the top dead center of the needle unit 620 may be positioned at the target point. It may be disposed above the skin surface.
  • one or more needles 621 may repeatedly invade the deep portion of the skin at the target point.
  • the one or more needles 621 may protrude downward through the open portion formed in the lower surface of the second space 2 of the second cylinder 612 and then return (return) upward.
  • the depth of invasion of the one or more needles 621 may be approximately 2.1 mm.
  • Holder 622 may be a member that supports one or more needles 621.
  • the holder 622 may be disposed in the second space 2 of the second cylinder 612, like the one or more needles 621.
  • the holder 622 may be disposed on a lower surface of the second plunger 623-2 and may be coupled to the second plunger 623-2.
  • the holder 622 may be omitted, in which case one or more needles 621 may be disposed directly on the plunger 623.
  • the plunger 623 may reciprocate downwardly and upwardly to form a first space 1 and a second space 2 in the cylinder 610.
  • the plunger 623 may be formed with a first channel 3 connecting the first space 1 and the second space 2.
  • the amount of change in the volume of the first space 1 due to the reciprocating movement of the plunger 623 is greater than the amount of change in the volume of the second space 2, so that the gas in the second space 2 is lowered when the plunger 623 moves downward.
  • the first space 3 may move to the first space 1, and when the plunger 623 moves upward, gas in the first space 1 passes through the first channel 3 to the second space 2. Can be moved.
  • one or more needles 621 may invade the skin when the plunger 623 moves downward, and a negative pressure state may be formed (pressure decrease) in the second space 2, and one or more needles when the plunger 623 moves upward. 621 is discharged from the skin and a positive pressure state may be formed (increase in pressure) in the second space (2).
  • the plunger 623 may include a first plunger 623-1 and a second plunger 623-2.
  • the first plunger 623-1 may be disposed in an inner space of the first cylinder 611.
  • the first plunger 623-1 closes the internal space of the first cylinder 611 in the vertical direction, and the first space 1 located above the first cylinder 611 and the excess space located below the first cylinder 611. 1-1) can be formed.
  • the first plunger 623-1 may reciprocate in the vertical direction by the driving force of the driving module 700.
  • the first plunger 623-1 moves downward, the volume of the first space 1 may increase, and the volume of the surplus space 1-1 may decrease (see FIG. 5 (1)).
  • the first plunger 623-1 moves upward, the volume of the first space 1 can be reduced, and the volume of the surplus space 3 can be increased (see FIG. 5 (2)).
  • the second plunger 623-2 may be located in an inner space of the second cylinder 612.
  • the second plunger 623-2 may close the internal space of the second cylinder 612 in the vertical direction to form the second space 2 in the second cylinder 612.
  • the second plunger 623-2 may reciprocate in the vertical direction by the driving force of the driving module 700.
  • the volume of the second space 2 can be reduced (see (1) of FIG. 5).
  • the volume of the second space 2 may increase (see FIG. 5 (2)).
  • a first channel 3 connecting the first space 1 and the second space 2 may be formed in the first plunger 623-1 and the second plunger 623-2.
  • the first channel 3 formed in the first plunger 623-1 and the second plunger 623-2 has the first plunger 623-1 and the second plunger 623-2 in the vertical direction. It may be one or more flow passage (3-1) (formed in the first plunger and the second plunger) penetrating.
  • the connecting rod 625 may be disposed above the first plunger 623-1.
  • the connecting rod 625 may move in the vertical direction by the driving force of the driving module 700.
  • the connecting rod 625 may be connected to the driving module 700 and the first plunger 623-1 to transmit a driving force of the driving module 700 to the first plunger 623-1.
  • the needle unit 620 reciprocates in the vertical direction (up and down direction), and may repeatedly invade the skin at the target point (when a high frequency is applied to the skin core part). Heat energy generation).
  • the surface of the skin of the target site may be applied with a drug to alleviate the pain caused by invasion or to promote the regeneration of the wound.
  • the volume of the first space 1 may increase and the volume of the second space 2 may decrease.
  • the amount of change in the volume of the first space 1 is greater than the amount of change in the volume of the second space 2 due to the difference in the cross-sectional area perpendicular to the vertical direction of the first space 1 and the second space 2.
  • the gas in the second space 2 is connected to the first space 1 through the first channel 3. (See (1) of FIG. 5, movement by pressure difference due to difference in volume change).
  • the second space 2 is in a "negative pressure state (pressure decrease; in contrast, the first space is increased in pressure and positive pressure state)" to suck the surface of the skin of the target spot, and to increase the height of the skin of the surface of the target spot.
  • one or more of the needles 621 may invade to a uniform depth (the effect of invading to a uniform depth, because the plurality of needles are irradiated with a high frequency at the depth of invasion (preset depth) that meets the medical design conditions) ).
  • the volume of the first space 1 may decrease, and the volume of the second space 2 may increase.
  • the amount of change in the volume of the first space 1 is greater than the amount of change in the volume of the second space 2 due to the difference in the cross-sectional area perpendicular to the vertical direction of the first space 1 and the second space 2.
  • the gas in the first space 1 passes through the first channel 3 to the second space 2. (See (2) in FIG. 5, movement by pressure difference due to difference in volume change).
  • the second space 2 becomes a "positive pressure state (increased pressure; on the contrary, the first space decreases in pressure and a negative pressure state)" so that the drug applied to the surface of the skin of the target spot is invaded (the Deep injection into the hole formed by insertion and ejection (effect of injecting the drug deep into the deep skin).
  • a second channel 4 connecting the surplus space 1-1 and the outside may be formed in the first cylinder 611.
  • the second channel 4 can prevent the pressure of the gas in the surplus space 1-1 from interfering with the reciprocating movement of the first plunger 623-1 in the vertical direction. That is, when the needle unit 620 moves downward, air in the surplus space 1-1 can be leaked to the outside to remove the resistive force.
  • the first channel 3 of the present invention may have various forms in addition to one or more flow paths 3-1 formed in the plunger 623 described above.
  • the first channel 3 may be a gap 3-2 between the cylinder 610 and the plunger 623. .
  • the existing second channel 4 of the present invention is not formed.
  • the gasket 626 between the cylinder 610 and the plunger 623 is also omitted or the gap 3 between the cylinder 610 and the plunger 623 in the gasket 626 between the cylinder 626 and the plunger 623. -2) may be formed.
  • the first channel 3 connects the first space 1 to the second space 2 ( 3-3). That is, in the second modification of the present invention, the first channel 3 is provided as a separate member.
  • the shape of the first channel 3 may be a combination of at least one of the flow path 3-1, the gap 3-2, and the tube 3-3.
  • the third injecting tip 3600 of the third modification of the present invention the fourth injecting tip 4600 of the fourth modification of the present invention, and the agent of the present invention
  • a description will be given of a tip 5600 for injecting a fifth variant.
  • the present invention may have third to fifth modifications for forming a high positive pressure state in the second space (2).
  • the valve 5 is provided in the drug injection tip 3600 of the third modification of the present invention.
  • the valve 5 may connect the outside and the first space 1 in the open state.
  • the valve 5 may be opened when the plunger 623 moves downward (opened at a negative pressure of the first space), thereby allowing external air to flow into the first space 1.
  • the valve 5 may be closed when the plunger 623 moves upward (closed at a positive pressure of the first space), thereby preventing the air of the first space 1 from flowing out.
  • additional air is accumulated in the first space 1 when the plunger 623 moves downward, and external air additionally accumulated in the first space 1 when the plunger 623 moves upward.
  • the positive pressure of the second space 2 can be increased (increase of drug injection by the pumping effect).
  • the opening and closing of the valve 5 are not limited to being driven by electric, and may be driven automatically.
  • the valve 5 when the valve 5 is structurally opened in only one direction (the direction in which external air enters the first space), the valve 5 may be automatically opened only in the negative pressure state of the first space 1.
  • the third channel 6 connecting the first space 1 and the surplus space 1-1, the first space 1, At least one of the fourth channels 7 connecting to the outside may be formed.
  • the plunger 623 moves downward, external air flows into and accumulates in the first space 1 through the third channel 6 and the fourth channel 7.
  • the plunger 623 moves upward, external air accumulated in the first space 1 may move to the second space 2 to increase the positive pressure of the second space 2 (pumping). Increased drug infusion by effect).
  • the fourth channel 7 is not overlapped with the plunger 623 when the lower side of the plunger 623 moves, and is opened, and the plunger 623 when the upper side of the plunger 623 moves, Plunger) and can be closed (opening and closing by the movement of the plunger).
  • the drug injection tip 5600 of the fifth modified example of the present invention unlike the conventional drug injection tip 600, the surplus space (1-1) is not formed, instead of the external and the first A fifth channel 8 connecting the space 1 may be formed.
  • the fifth channel 8 is opened by the movement of the plunger 623 when the plunger 623 moves downward to accumulate outside air in the first space 1, and the plunger 623 when the plunger 623 moves upward.
  • the positive pressure in the second space 2 can be increased by closing the closed space by allowing the air in the first space 1 to be completely transferred to the second space 2 (drug injection by the pumping effect). Growth).
  • the drive module 700 may be embedded in the hand piece 500 and may provide a driving force for reciprocating the needle unit 620 of the tip 600 for drug injection.
  • Various kinds of driving devices may be used as the driving device of the driving module 700.
  • the drive module 700 may include a pneumatic cylinder or may include a linear motor.
  • the power supply module may be embedded in the hand piece 500 and may supply power to one or more needles 621.
  • the power supply module may supply DC power or AC power to one or more needles 621.
  • the power module may be electrically connected to the one or more needles 621 by the first conductive member 501, and may be electrically connected to the cable 400 by the second conductive member 502. Accordingly, the power supply module may receive a control signal of the electronic control module through the cable 400, and apply power corresponding thereto to one or more needles 621.
  • the seat 613 When the needle unit 620 moves upward, the seat 613 may be pushed downward by the flow of the gas in the second space 2 to increase the downward inclination angle. Accordingly, the sheet 613 may block the gas in the second space 2 from being discharged to the outside through the one or more grooves 612-1 of the second cylinder 612. As a result, the positive pressure formed in the second space 2 rises (external gas moved to the first space when the needle unit moves downward moves back to the second space when the needle unit moves upward and discharges to the outside). This blockage increases the positive pressure), so that the pumping effect can be increased (see FIG. 11 (2)).
  • Skin treatment method of the present invention comprises the step of (s100) the negative pressure state is formed in the second space (2) by moving the one or more needles (621) and plunger (623) downward (needle electrode insertion); Applying one or more needles 621 to the high frequency portion of the skin deep at the target point (S200); At least one needle 621 and the plunger 623 may be moved upwards (needle discharge) to form a positive pressure state in the second space 2 (S300).
  • one or more needles 621 are inserted into the skin, and the surface of the skin is formed by the negative pressure state of the second space 2.
  • the surface of the skin may be uniformly provided.
  • the one or more needles 621 may be invaded to a predetermined depth and the therapeutic effect may be enhanced.
  • heat energy may be generated in the deep skin to remove the waste tissue of the skin (skin regeneration and treatment effect).
  • one or more needles 621 may be discharged from the skin, and the drug may be injected into a hole formed in the skin. That is, holes may be formed in the skin by inserting and discharging the one or more needles 621, and the drug may be injected into the holes formed in the skin in a positive pressure state of the second space 2.
  • the positive pressure state is formed in the second space 2 (s300), and the second space 2 is set to the negative pressure state.
  • Negative pressure formed in step S100 holes formed in the skin may be opened. After that, if a positive pressure is formed in the second space 2, the drug may be injected under pressure through a gaping hole to be injected deep into the skin.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne une pointe d'injection de médicament qui introduit une aiguille à une profondeur prédéterminée en profondeur dans la peau, et en même temps, injecte un médicament à travers un trou dans la peau formé par l'aiguille, une pièce à main sur laquelle la pointe est montée, et un dispositif de traitement de la peau utilisant la pointe. La pointe d'injection de médicament comprend : un cylindre; un piston animé d'un mouvement de va-et-vient vers le bas et vers le haut, et formant un premier espace et un second espace à l'intérieur du cylindre; et une aiguille disposée dans le piston et dans le second espace du cylindre, lorsque le piston se déplace vers le bas, l'aiguille est insérée dans la peau pour former un état de pression négative dans le second espace, et lorsque le piston se déplace vers le haut, l'aiguille est déchargée de la peau pour former un état de pression positive dans le second espace.
PCT/KR2019/007319 2018-07-02 2019-06-18 Pointe d'injection de médicament, pièce à main et dispositif de traitement de la peau WO2020009351A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP19829896.0A EP3819004B1 (fr) 2018-07-02 2019-06-18 Pointe d'injection de médicament, pièce à main et dispositif de traitement de la peau
JP2020573399A JP7244115B2 (ja) 2018-07-02 2019-06-18 薬物注入用チップ、ハンドピース及び皮膚処置装置
EP22201267.6A EP4137197B1 (fr) 2018-07-02 2019-06-18 Pointe d'injection de médicament, pièce à main et dispositif de traitement de la peau
EP24164484.8A EP4364769A2 (fr) 2018-07-02 2019-06-18 Pointe d'injection de médicament, pièce à main et dispositif de traitement de la peau
CN201980042717.3A CN112368046A (zh) 2018-07-02 2019-06-18 药物注入用顶端件、手持件及皮肤处理装置
US16/697,163 US11376374B2 (en) 2018-07-02 2019-11-26 Medicine injecting tip, hand piece, and skin treating device
IL279842A IL279842A (en) 2018-07-02 2020-12-29 A tip for injecting medicine, a hand tool, and a device for skin care
US17/826,737 US20220288327A1 (en) 2018-07-02 2022-05-27 Medicine injecting tip, hand piece, and skin treating device

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2018-0076601 2018-07-02
KR20180076601 2018-07-02
KR10-2018-0154688 2018-12-04
KR1020180154688A KR102062219B1 (ko) 2018-07-02 2018-12-04 약물 주입용 팁, 핸드 피스 및 피부 처치 장치

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US16/697,163 Continuation US11376374B2 (en) 2018-07-02 2019-11-26 Medicine injecting tip, hand piece, and skin treating device

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Publication Number Publication Date
WO2020009351A1 true WO2020009351A1 (fr) 2020-01-09

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021226281A1 (fr) * 2020-05-05 2021-11-11 Cynosure, Llc Dispositifs à réseau d'aiguilles et méthodes associées

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Publication number Priority date Publication date Assignee Title
JP2000287992A (ja) * 1999-04-01 2000-10-17 Olympus Optical Co Ltd 高周波焼灼装置
KR100532671B1 (ko) * 2003-02-19 2005-12-01 (주) 태웅메디칼 고주파 열치료용 전극 장치
JP2011083347A (ja) * 2009-10-14 2011-04-28 Hoya Corp 超音波内視鏡用穿刺針装置
KR101286752B1 (ko) * 2012-09-03 2013-07-16 라종주 체내 시술 장치 및 이를 구비한 내시경 장치
KR101596716B1 (ko) * 2015-06-19 2016-02-24 주식회사 스타메드 시술장치

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000287992A (ja) * 1999-04-01 2000-10-17 Olympus Optical Co Ltd 高周波焼灼装置
KR100532671B1 (ko) * 2003-02-19 2005-12-01 (주) 태웅메디칼 고주파 열치료용 전극 장치
JP2011083347A (ja) * 2009-10-14 2011-04-28 Hoya Corp 超音波内視鏡用穿刺針装置
KR101286752B1 (ko) * 2012-09-03 2013-07-16 라종주 체내 시술 장치 및 이를 구비한 내시경 장치
KR101596716B1 (ko) * 2015-06-19 2016-02-24 주식회사 스타메드 시술장치

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021226281A1 (fr) * 2020-05-05 2021-11-11 Cynosure, Llc Dispositifs à réseau d'aiguilles et méthodes associées
US11806522B2 (en) 2020-05-05 2023-11-07 Cynosure, Llc Needle-array devices and related methods

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