WO2019207840A1 - Armoire de sécurité - Google Patents

Armoire de sécurité Download PDF

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Publication number
WO2019207840A1
WO2019207840A1 PCT/JP2018/047462 JP2018047462W WO2019207840A1 WO 2019207840 A1 WO2019207840 A1 WO 2019207840A1 JP 2018047462 W JP2018047462 W JP 2018047462W WO 2019207840 A1 WO2019207840 A1 WO 2019207840A1
Authority
WO
WIPO (PCT)
Prior art keywords
safety cabinet
temperature
work
air
cabinet according
Prior art date
Application number
PCT/JP2018/047462
Other languages
English (en)
Japanese (ja)
Inventor
金子　健
博利 佐藤
Original Assignee
株式会社日立産機システム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社日立産機システム filed Critical 株式会社日立産機システム
Publication of WO2019207840A1 publication Critical patent/WO2019207840A1/fr

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L1/00—Enclosures; Chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F11/00—Control or safety arrangements
    • F24F11/70—Control systems characterised by their outputs; Constructional details thereof
    • F24F11/80—Control systems characterised by their outputs; Constructional details thereof for controlling the temperature of the supplied air
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F11/00—Control or safety arrangements
    • F24F11/89—Arrangement or mounting of control or safety devices
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F7/00—Ventilation
    • F24F7/007—Ventilation with forced flow
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24—HEATING; RANGES; VENTILATING
    • F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F7/00—Ventilation
    • F24F7/04—Ventilation with ducting systems, e.g. by double walls; with natural circulation
    • F24F7/06—Ventilation with ducting systems, e.g. by double walls; with natural circulation with forced air circulation, e.g. by fan positioning of a ventilator in or against a conduit

Definitions

  • the present invention relates to a safety cabinet that is a facility for realizing a safe working environment in order to handle microorganisms and pathogens.
  • Patent Document 1 discloses that in a safety cabinet that exhausts to the outside through an open duct connection, a problem occurs in the outdoor exhaust duct system, and exhaust air from the safety cabinet containing a small amount of volatile harmful substances is tested from the opening of the open duct. Disclosed is a safety cabinet that generates an alarm when there is a possibility of leaking into a room.
  • Patent Document 2 when an operator performs a work while checking a standard work procedure manual and sample data using a safety cabinet, a display device such as a monitor screen provided in the safety cabinet is subjected to irregular reflection due to light from a fluorescent lamp.
  • a technology that is placed at a position that is not affected by deterioration due to irradiation with germicidal lamps and that does not become a resistance to the air flow path, protects it from decontamination work, and also prevents dirt from adhering to parts related to the display. Disclosure.
  • Samples used in a safety cabinet are often cultured and propagated in a constant temperature bath (incubator) at about 35 ° C., for example.
  • the safety cabinet that operates on the sample is at room temperature, and the temperature is not adjusted.
  • Patent Document 1 and Patent Document 2 there is no disclosure about adjusting the temperature of the sample in the safety cabinet.
  • the temperature is not adjusted, so there is a temperature difference between the incubation time of the sample and the operation performed in the safety cabinet, which can affect the state of the sample. There is.
  • An object of the present invention is to provide a safety cabinet that can reduce the influence of temperature on a sample.
  • a preferred example of the present invention includes a work stage for performing work, a work space where an operator works, a front plate formed on the front surface of the work space, a work opening connected to the work space, and the work opening.
  • a safety cabinet having exhaust means for sucking air and exhausting air in the work space to the outside of the safety cabinet through an air cleaning means, and temperature adjusting means for adjusting the temperature of the work space.
  • the influence of temperature on the sample can be reduced.
  • FIG. 1 is a schematic side view of a safety cabinet illustrating Example 1.
  • FIG. 6 is a schematic side view of a safety cabinet for explaining Example 3.
  • FIG. 6 is a schematic side view of the safety cabinet explaining Example 4.
  • FIG. 1 shows a schematic front view of the safety cabinet.
  • FIG. 2 is a schematic side view of the safety cabinet when the A-A ′ cross section of FIG. 1 is viewed from the right side.
  • An opening is provided in the central area of the casing 101 of the safety cabinet 100, and a work space 104 is provided in the back thereof.
  • a front plate 102 is provided on the front side of the work space 104 so as to block the upper portion of the opening, and a work opening 103 is provided on the lower side thereof. The operator puts his hand into the work space 104 from the work opening 103. Do the work.
  • the front plate 102 is formed of a transparent material such as glass, and an operator can visually observe the work through the front plate.
  • a substantially flat work stage 105 is provided on the bottom surface of the work space 104, and the worker performs work on the work stage.
  • An intake port 107 leading to the lower side is provided on the front side of the work stage 105 and in the vicinity of the work opening 103.
  • the air inlet 107 is formed by a slit extending in the left-right direction of the housing along the work opening 103.
  • a back channel 108 that leads from the air inlet 107 to the upper part of the housing is provided.
  • a blow-out side FFU (fan filter unit) 109 is provided above the work space 104.
  • the blow-out side FFU 109 is configured by a fan that is driven by a motor and rotates, which is a blower, and a filter that removes fine particles, for example, a HEPA filter 109A that is an air purifier. Clean air from which fine particles have been removed is blown out into the work space 104 by the blow-out side FFU 109.
  • An exhaust-side FFU (fan filter unit) 110 is provided on the upper portion of the casing 101, and a part of air is removed through a filter, for example, a HEPA filter 110A, and discharged to the outside of the apparatus.
  • Fig. 3 shows the air flow with arrows when the safety cabinet is operating.
  • the air 90 sucked from the air inlet 107 on the front side of the work stage 105 passes through the lower part of the casing, the rear passage 108, and the upper part of the casing as indicated by reference numeral 91, and then enters the work space 104 from the blowout side FFU 109. Be blown.
  • the work space 104 is maintained in a clean state by blowing clean air from which fine particles have been removed by the HEPA filter 109A of the blow-out side FFU 109 into the work space 104.
  • the air in the work space may leak to the outside only by the flow of air to the work space 104 indicated by reference numeral 92. Therefore, the discharge side FFU 110 is provided, and part of the air is discharged to the outside through the HEPA filter 110A. As a result, the pressure in the work space decreases, and an air flow 94 is generated from the outside to be introduced into the inside through the work opening 103 below the front plate 102. If this air flow 94 flows into the work space as it is, the cleanliness of the work space is lowered.
  • FIG. 4 is a schematic side view of a safety cabinet for explaining the first embodiment.
  • the temperature adjusting means 20 that adjusts the temperature of the work space 104 is disposed below the work stage 105 so as to come into contact with the work stage 105 in the housing 101 of the safety cabinet 100.
  • the temperature adjusting means 20 includes heating means such as a wire heater, a cotton-like heating element, a ceramic heater, a nichrome wire heater, and application of heat-generating paint by electrical conduction such as carbon. Further, the temperature adjusting means 20 may have a cooling / heating mechanism for constant temperature control. Examples of the cooling / heating mechanism include a water pipe and a Peltier element below the stage. The temperature adjusting means 20 may have the same function as the air conditioner. You may form integrally with the work stage 105. FIG.
  • the influence of the temperature on the sample placed in the work space can be reduced.
  • the temperature setting value of the temperature adjusting means 20 may be specified by the user from, for example, a touch panel provided at the upper front of the safety cabinet 100.
  • the temperature sensor 30 may be provided on the work stage 105, and the temperature of the temperature adjusting means 20 may be controlled based on the temperature detected by the temperature sensor 30.
  • the position where the temperature sensor 30 is installed is preferably close to the work stage 105. This is because the temperature of the sample can be detected more correctly by arranging it close to the sample.
  • the control unit of the motor that drives the fan reduces the number of rotations of the motor, reduces the operation of the fan of the exhaust side FFU (fan filter unit) 110, and discharges air flow 93 It may be controlled to reduce the amount.
  • temperature adjustment such as temperature rise can be performed more quickly and easily.
  • the state of the exhaust side FFU (fan filter unit) 110 during operation reduction operation may be stored in a database in advance, and the fan operation may be controlled with reference to the table or the like.
  • FIG. 5 is a schematic side view of a safety cabinet for explaining the second embodiment. The description which overlaps with Example 1 is omitted.
  • the temperature adjusting means 20 is provided in the circulation path of the air flow.
  • the temperature adjusting means 20 is disposed in the path of the air flow 91 below the work stage 105.
  • the temperature adjusting means 20 may be provided in the circulation path of the air flow.
  • the temperature adjusting means 20 may also have a cooling / heating means.
  • the temperature sensor 30 may be provided on the work stage 105, and the temperature of the temperature adjusting unit 20 may be controlled based on the temperature detected by the temperature sensor 30.
  • Example 2 since the warmed air flow 92 is clean air and flows toward the sample placed on the work stage 105, the cultured tissue itself on the petri dish can be directly heated, Since the air is directly applied to the work stage 105 having a free area, the work stage 105 can be heated.
  • FIG. 6 is a schematic side view of a safety cabinet for explaining the third embodiment. The description which overlaps with Example 1 is omitted.
  • a temperature adjusting means is provided on the blowout side FFU 109.
  • the air flow 94 is always introduced from the outside, and accordingly, the air flow 94 continues to be discharged to the outside in order to form a negative pressure. In other words, a part of the warmed air is always released to the outside and the cold external atmosphere is continuously introduced.
  • the temperature adjustment means 22 is arranged on the blow-out side FFU 109, and the temperature of the work space region is increased to a higher temperature state by adjusting the temperature of the air introduced into the work space 104 more efficiently. Such temperature control can be realized.
  • the temperature adjusting means 22 is provided on the blowout side FFU 109.
  • the case where the temperature adjusting means 20 is provided below the work stage may be used in combination with this embodiment.
  • the case where the temperature adjusting means 20 is provided in the circulation path through which the air flows may be used in combination with the present embodiment.
  • FIG. 1 Example 1
  • FIG. 7 is a schematic side view of a safety cabinet for explaining the fourth embodiment. The description which overlaps with Example 1 is omitted.
  • a first AC cord 31 and a second AC cord 32 are provided in the safety cabinet 100.
  • the safety cabinet 100 is operated with a low-voltage power supply (AC100V in Japan). This is because a large current is not particularly required. However, if the temperature of the entire safety cabinet 100 is to be raised or lowered, a large amount of power is required to adjust the temperature. For this reason, in a normal 100V electric power feeding system, current capacity is exceeded, which may lead to overheating of the cable or interruption due to a breaker. Therefore, an AC cord other than for temperature adjustment and an AC cord for power supply used for temperature adjustment are separated, and a plurality of AC cords are provided in total.
  • AC100V in Japan
  • the amount of current per line can be reduced, and safe power feeding is realized.
  • a large amount of power for example, when all of the temperature adjusting means 20 shown in the first to third embodiments are provided in the safety cabinet 100, a plurality of heating power supply cords are provided. Also good.
  • the wiring in the safety cabinet ahead of the AC cord is also separated in the power feeding system using the first AC cord 31 and the power feeding system using the second AC cord 32.
  • the simplest means for reducing the amount of current is to increase the power supply voltage. Therefore, by setting the first AC cord 31 to 100 V and the second AC cord 32 for the temperature control means 20 to a higher voltage (for example, 200 V), the amount of current in the heating system path is 100 V. In contrast, in the case of 200V, it can be halved and a safe supply of electric power can be realized.
  • Japanese Patent Laid-Open No. 2006-71233 describes a technique for transmitting temperature information of a refrigerator, a freezer, and a high-pressure steam sterilizer to an information processing device and monitoring information on those devices installed in a biohazard countermeasure room from the outside.
  • Japanese Patent Laid-Open No. 2001-104835 stores the setting information when the centrifuge is in use so that it can be used with the same setting. Temperature is described as one of the setting information.
  • temperature information is received from outside the device of the safety cabinet 100, and the temperature in the work space 104 is controlled based on the temperature information.
  • a safety cabinet 100 is described.
  • the safety cabinet 100 compares the temperature information from the temperature sensor 30 provided in the work space 104 with the heating means of the temperature adjusting means 20 according to the temperature difference.
  • the set temperature of the temperature adjusting means 20 is controlled so as to reduce the temperature difference between the outside and the work space 104 by functioning or by causing the cooling / heating means to function.
  • the temperature information from the temperature sensor 30 is utilized for the temperature control of the work space 104, and the output of the heating means and the cooling / heating means is changed, or the outside air is taken in. You can change the amount of air sucked from your mouth.
  • the temperature information from outside the safety cabinet device is the temperature information of a constant temperature incubator (incubator)
  • the temperature of the work space 104 of the safety cabinet is controlled to be higher than the external temperature of the safety cabinet, for example, room temperature
  • the influence of environmental changes on the cells can be reduced.
  • the temperature information from the outside of the safety cabinet is the temperature information of the refrigerator or freezer
  • the temperature of the work area of the safety cabinet is controlled to be lower than the external temperature of the safety cabinet, for example, room temperature.
  • the influence of environmental changes on the cells can be reduced.
  • the safety cabinet 100 may be provided with a function capable of selecting temperature information from the outside depending on the work.
  • the safety cabinet 100 is connected to a constant temperature incubator, a refrigerator, or a freezer by means of direct communication with the safety cabinet 100.
  • the temperature information may be selected by operating a changeover switch provided in the safety cabinet 100.
  • the safety cabinet 100 when not only the safety cabinet 100 but also a constant temperature incubator, a refrigerator, a freezer, and a centrifuge are connected by a network and the temperature information is received by the safety cabinet via the information processing device, the safety cabinet has a network. And a display unit that displays communication information with the information processing apparatus connected to the information processing apparatus, and a transmission unit that transmits a temperature information selection command to the information processing apparatus.
  • Example 5 since the temperature of the safety cabinet 100 is adjusted based on the temperature of the constant temperature incubator, the refrigerator, or the freezer, the influence of the temperature on the work object can be further reduced.

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Combustion & Propulsion (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Ventilation (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Air Conditioning Control Device (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Cette armoire de sécurité a un étage de travail sur lequel un travail est effectué, un espace de travail dans lequel un ouvrier travaille, une plaque de face avant qui est formée au niveau de la face avant de l'espace de travail, une ouverture de travail qui se raccorde à l'espace de travail, un moyen d'évacuation d'air qui aspire l'air de l'ouverture de travail et évacue l'air à l'intérieur de l'espace de travail vers l'extérieur de l'armoire de sécurité par l'intermédiaire d'un moyen de purification d'air, et un moyen de réglage de température qui règle la température dans l'espace de travail.
PCT/JP2018/047462 2018-04-24 2018-12-25 Armoire de sécurité WO2019207840A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018-083423 2018-04-24
JP2018083423A JP7028706B2 (ja) 2018-04-24 2018-04-24 安全キャビネット

Publications (1)

Publication Number Publication Date
WO2019207840A1 true WO2019207840A1 (fr) 2019-10-31

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PCT/JP2018/047462 WO2019207840A1 (fr) 2018-04-24 2018-12-25 Armoire de sécurité

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JP (1) JP7028706B2 (fr)
WO (1) WO2019207840A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102517048B1 (ko) * 2020-11-30 2023-04-03 (주)노바프로 듀얼 양압챔버를 구비하는 생물안전작업대

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59120086A (ja) * 1982-12-28 1984-07-11 Fuji Electric Co Ltd バイオハザ−ドセフテイキヤビネツト
JPS60154646A (ja) * 1984-01-25 1985-08-14 Hitachi Micro Comput Eng Ltd 半導体装置
JPH01285185A (ja) * 1988-05-10 1989-11-16 Taisei Corp 環境調節施設
JP2002320328A (ja) * 2001-04-20 2002-10-31 Matsushita Electric Ind Co Ltd 調理器
JP2004351283A (ja) * 2003-05-28 2004-12-16 Hitachi Industrial Equipment Systems Co Ltd 安全キャビネット及び空気清浄手段交換後処理方法
JP2009103481A (ja) * 2007-10-22 2009-05-14 Yokogawa Electric Corp 半導体検査装置
WO2017081572A1 (fr) * 2015-11-09 2017-05-18 Kivex Biotec A/S Station de travail à flux d'air laminaire à régulation de la température

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005279575A (ja) * 2004-03-30 2005-10-13 Sanyo Electric Co Ltd クリーンベンチ
CN107349989A (zh) * 2017-09-15 2017-11-17 黎明职业大学 一种可升降台面实验台

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59120086A (ja) * 1982-12-28 1984-07-11 Fuji Electric Co Ltd バイオハザ−ドセフテイキヤビネツト
JPS60154646A (ja) * 1984-01-25 1985-08-14 Hitachi Micro Comput Eng Ltd 半導体装置
JPH01285185A (ja) * 1988-05-10 1989-11-16 Taisei Corp 環境調節施設
JP2002320328A (ja) * 2001-04-20 2002-10-31 Matsushita Electric Ind Co Ltd 調理器
JP2004351283A (ja) * 2003-05-28 2004-12-16 Hitachi Industrial Equipment Systems Co Ltd 安全キャビネット及び空気清浄手段交換後処理方法
JP2009103481A (ja) * 2007-10-22 2009-05-14 Yokogawa Electric Corp 半導体検査装置
WO2017081572A1 (fr) * 2015-11-09 2017-05-18 Kivex Biotec A/S Station de travail à flux d'air laminaire à régulation de la température

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JP2019190721A (ja) 2019-10-31
JP7028706B2 (ja) 2022-03-02

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