WO2019154015A2 - Composé contenant de l'argon, son procédé de préparation et son utilisation - Google Patents

Composé contenant de l'argon, son procédé de préparation et son utilisation Download PDF

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Publication number
WO2019154015A2
WO2019154015A2 PCT/CN2019/071383 CN2019071383W WO2019154015A2 WO 2019154015 A2 WO2019154015 A2 WO 2019154015A2 CN 2019071383 W CN2019071383 W CN 2019071383W WO 2019154015 A2 WO2019154015 A2 WO 2019154015A2
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WO
WIPO (PCT)
Prior art keywords
acid
argon
containing compound
extract
pain
Prior art date
Application number
PCT/CN2019/071383
Other languages
English (en)
Chinese (zh)
Inventor
杨建中
Original Assignee
杨建中
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 杨建中 filed Critical 杨建中
Publication of WO2019154015A2 publication Critical patent/WO2019154015A2/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B23/00—Noble gases; Compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B23/00—Noble gases; Compounds thereof
    • C01B23/0005—Compounds of noble gases
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/72—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by d-values or two theta-values, e.g. as X-ray diagram
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
    • C01P2002/00—Crystal-structural characteristics
    • C01P2002/70—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data
    • C01P2002/77—Crystal-structural characteristics defined by measured X-ray, neutron or electron diffraction data by unit-cell parameters, atom positions or structure diagrams

Definitions

  • the inflammation is an infectious disease such as inflammation caused by an influenza virus or the like.
  • Analgesic test of the compound of the invention acute thermal allodynia test (appendix method)
  • Each group was formulated to have a gastric perfusion amount of 2 mL/100 g.
  • Sprague-Dawley rats were injected with 50% complete 50% complete Freund's adjuvant (CFA) on the right toe, and then randomly divided into 4 groups (8 in each group), ie model control group, low dose group (8 mg/ Kg), medium dose group (16 mg/kg), ibuprofen capsule group (50 mg/kg). Serum was administered once daily at 9:00 am and 17:00 pm at the dose of 1/2 of the above dose, and serum was taken for 30 minutes after the morning of the third day.
  • CFA complete Freund's adjuvant
  • the compounds of the present invention have a significant improvement in immune function.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PCT/CN2019/071383 2018-02-09 2019-01-11 Composé contenant de l'argon, son procédé de préparation et son utilisation WO2019154015A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201810132871.7 2018-02-09
CN201810132871.7A CN110127642B (zh) 2018-02-09 2018-02-09 含氩化合物及其制备方法和用途

Publications (1)

Publication Number Publication Date
WO2019154015A2 true WO2019154015A2 (fr) 2019-08-15

Family

ID=67548040

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2019/071383 WO2019154015A2 (fr) 2018-02-09 2019-01-11 Composé contenant de l'argon, son procédé de préparation et son utilisation

Country Status (2)

Country Link
CN (1) CN110127642B (fr)
WO (1) WO2019154015A2 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100391533C (zh) * 2005-05-16 2008-06-04 吉林大学 鼠妇镇痛肽及其制备方法和应用
CN101176549B (zh) * 2007-11-29 2011-12-14 湖北东方天琪生物工程股份有限公司 从虾壳中提取甲壳素及其生物活性物质的低耗环保方法
CN101708190B (zh) * 2009-12-16 2013-12-04 中国人民解放军第四军医大学 鼠妇提取物的制备方法及其在消炎镇痛药物中的应用
CN102643368B (zh) * 2012-05-07 2014-04-09 连云港职业技术学院 一种从虾头及虾下脚料中同步提取牛磺酸和甲壳素及多肽的方法

Also Published As

Publication number Publication date
CN110127642A (zh) 2019-08-16
CN110127642B (zh) 2020-10-20

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