WO2019142757A1 - Instrument auxiliaire et procédé d'insertion de tube endotrachéal pour souris utilisant ledit instrument - Google Patents

Instrument auxiliaire et procédé d'insertion de tube endotrachéal pour souris utilisant ledit instrument Download PDF

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Publication number
WO2019142757A1
WO2019142757A1 PCT/JP2019/000843 JP2019000843W WO2019142757A1 WO 2019142757 A1 WO2019142757 A1 WO 2019142757A1 JP 2019000843 W JP2019000843 W JP 2019000843W WO 2019142757 A1 WO2019142757 A1 WO 2019142757A1
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WO
WIPO (PCT)
Prior art keywords
endotracheal tube
mouse
opening
shaft member
auxiliary tool
Prior art date
Application number
PCT/JP2019/000843
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English (en)
Japanese (ja)
Inventor
卓 西野
久予 神
Original Assignee
国立大学法人千葉大学
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 国立大学法人千葉大学 filed Critical 国立大学法人千葉大学
Priority to JP2019566454A priority Critical patent/JP7309199B2/ja
Publication of WO2019142757A1 publication Critical patent/WO2019142757A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A61D7/04—Devices for anaesthetising animals by gases or vapours; Inhaling devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/04—Tracheal tubes

Definitions

  • the present invention relates to an aid and a method of intubating a mouse endotracheal tube using the same.
  • the position of the larynx can be accurately grasped using the image taken by a camera attached to the endoscope, and the endotracheal tube is It is excellent in that it can be intubated in the tube.
  • Kenjiro KONNO et al., “New Visible Endotracheal Intubation Method Using the Endoscope System for Mice Inhalational Anesthesia”, J. Vet. Med. Sci, 2014, 76 (6), p. 863-868 Crotaz IR, "Initial feasibility investigation of the v-gel airway: an anatomically designed" "supprestive airway device for use in companion animal veterinary anaesthesia", veterinary Anaesthesia and Analgesia, 2010, 37, p. 579-580
  • Non-Patent Document 2 a device obtained by modifying the supraglottic airway securing device (v-gel) (see, for example, Non-Patent Document 2) applicable to laryngeal masks applicable to animals such as rabbits. It is also conceivable to use it to intubate an endotracheal tube into the airway of the mouse.
  • v-gel supraglottic airway securing device
  • the above-mentioned device originally merely covers the larynx and does not intubate the endotracheal tube, and additionally, the pharyngeal shape of the mouse is very small compared to a rabbit or the like, and the shape is not a mere similar shape.
  • the mere modification of the above device can not be applied to the intubation of an endotracheal tube into a mouse.
  • the mouse may be excessively stressed due to an erroneous operation or the like, and there is a possibility that the mouse may be killed by being forcibly pushed.
  • the present invention has been made based on the circumstances as described above, and its object is to make it possible to intubate the endotracheal tube of a mouse reliably, quickly and easily without using expensive equipment.
  • An aid for guiding an endotracheal tube into the trachea of a mouse via the larynx A shaft member having a through hole through which the endotracheal tube is inserted; A mask member connected to one end of the shaft member and abutting at least a part of the periphery of the laryngeal opening in the pharynx; The mask member has an opening communicating with the through hole of the shaft member, An auxiliary tool characterized in that a delivery direction of the endotracheal tube through the opening is formed at an acute angle with respect to a distal direction of the shaft member.
  • the auxiliary tool according to the above (1) wherein the mask member has a deflection unit that deflects the advancing direction of the endotracheal tube.
  • the tube according to the above (1) which is formed so as to allow the endotracheal tube to be inserted therein and communicate with the through hole of the shaft member and has a curved pipe member for deflecting the advancing direction of the endotracheal tube.
  • the tip is located in the middle of the shaft body in the axial direction of the shaft member, and includes a projecting member protruding from the outer peripheral surface of the shaft body according to any one of (1) to (3) Auxiliary equipment, (5) The auxiliary tool according to (4), wherein the projecting members are arranged to be symmetrical with respect to a virtual plane passing through the axis of the shaft member and the center of the opening.
  • the shaft member has a marker at an outer peripheral portion of a predetermined distance along the proximal end direction of the shaft member from the end of the opening in the proximal direction, any of the above (1) to (5) Auxiliaries listed in paragraph 1 or (7) Any one of the above items (1) to (6), wherein the delivery direction of the endotracheal tube through the opening is formed so as to be 4 ° or more and 30 ° or less with respect to the distal end direction of the shaft member And (8) a method of intubating an endotracheal tube for a mouse, which guides the endotracheal tube into the endotracheal space of the mouse through the larynx.
  • the “tip direction” is a direction along the axial direction of the shaft member, and is the direction of the end where the mask member is provided with respect to the end where the mask member of the shaft member is not provided.
  • proximal direction means a direction along the axial direction of the shaft member and means the direction opposite to the distal direction.
  • distal end indicates the distal end of any member or site, and “proximal” indicates the proximal end of any member or site.
  • the "predetermined distance” is defined as the length along the mouth and pharynx of the mouse and corresponds to the standard length between a specific part of the mouse body (for example, incisor teeth) and the laryngeal opening. Means the distance
  • the present invention provides an aid capable of reliably, quickly and easily intubating the endotracheal tube of the endotracheal tube without using an expensive instrument, and a method of intubating the endotracheal tube for a mouse using the same. Can be provided.
  • FIG. 5 is a schematic plan view of FIG. 4;
  • FIG. 10 is a schematic plan view showing a third embodiment of the present invention, wherein (a) to (d) show an assisting tool provided with projecting members of various shapes.
  • FIG. 1 It is a schematic side view showing a 3rd embodiment of the present invention, and (a)-(f) show the auxiliary tool provided with the projection member of various shapes, respectively. It is the schematic which shows the use condition of FIG. 1, Comprising: (a) is a state which inserted the auxiliary tool in the intraoral area, (b) is a state which pressed the mask member of the auxiliary tool to the larynx, (c) is the endotracheal region. (D) shows a state in which an endotracheal tube is inserted into the trachea.
  • the auxiliary tool is an auxiliary tool for guiding an endotracheal tube into the trachea of a mouse via the larynx, and includes a shaft body having a through hole through which the endotracheal tube is inserted. And a mask member connected to one end of the shaft member and in contact with at least a part of the periphery of the larynx opening in the pharynx, the mask member having an opening communicating with the through hole of the shaft member It is characterized in that the delivery direction of the endotracheal tube through the opening portion is formed to have an acute angle with respect to the distal direction of the shaft member.
  • the endotracheal tube applied to the auxiliary tool is a flexible tube that can be bent along the through hole of the auxiliary tool, and for example, gas such as anesthetic gas or oxygen is transmitted through the endotracheal tube. Supply air to the trachea or exhale from the trachea to the outside.
  • the outer diameter of the endotracheal tube is about 0.8 mm to 1.2 mm.
  • FIG. 1 is a schematic cross-sectional view showing a first embodiment of the present invention.
  • assistant tool 1 is roughly comprised by the shaft member 11 and the mask member 21 as shown in FIG.
  • the shaft member 11 comprises a shaft body 110.
  • the shaft member 11 may also have a marker 120.
  • the shaft main body 110 is a member having a through hole 111 through which the endotracheal tube t is inserted.
  • the shaft body 110 is formed in, for example, a substantially cylindrical shape so as to have a through hole 111 which penetrates along the direction of the axis of the shaft member 11 (the axis of the shaft body 110).
  • each part of the shaft body 110 are generally 15 mm to 20 mm in total length so that when the auxiliary tool 1 is inserted through the oral cavity of the mouse, the opening 211 of the mask member 21 described later reliably reaches the larynx opening.
  • the outer diameter is usually 3 mm to 5 mm so that it can be easily inserted into the pharynx of the mouse.
  • the inner diameter is usually 1 mm to 2 mm depending on the outer diameter of the endotracheal tube t.
  • the material constituting the shaft main body 110 is not particularly limited, but is preferably made of a flexible material from the viewpoint of being able to smoothly insert the auxiliary 1 along the pharynx, and polyester resin, salt Polyvinylated resins are more preferred, and polyester resins are even more preferred. Further, the shaft body 110 may be one in which a layer such as silicone resin is laminated on the outer periphery of a member formed using the above-mentioned material.
  • the marker 120 is a mark for grasping the position of the opening 211 of the mask member 21 in the pharynx of the mouse.
  • the marker 120 is provided on the surface of the shaft body 110 and at an outer peripheral portion of a predetermined distance L4 (see FIG. 3) along the proximal direction of the shaft member 11 from the end p of the opening 211 in the proximal direction. It is done.
  • a part or the whole circumference in the circumferential direction in the outer peripheral part is colored with a pigment or the like, and a shape such as a convex part or a recess around the part or the entire circumference in the circumferential direction in the outer peripheral part It is possible to employ one in which a typical feature portion is formed.
  • a marker 120 (see FIG. 1 and FIG. 2) colored using a pigment is illustrated on the entire circumference of the outer peripheral portion.
  • the predetermined distance L4 for example, the same value as the average length between the incisor teeth and the laryngeal opening of a standard mouse can be adopted.
  • the distance between the marker 120 and the end p of the mask portion 21 is preferably 11 mm or more and 12 mm or less, and more preferably 11.6 mm.
  • the mask member 21 is connected to one end of the shaft member 11 and abuts on at least a part of the larynx opening periphery in the pharynx. As shown in FIG. 2, the mask member 21 has an opening 211 communicating with the through hole 111 of the shaft member 11. Specifically, the mask member 21 is, for example, fixed so that the proximal end surrounds the opening of the distal end of the shaft main body 110, extends from the periphery of the opening toward the distal direction, And a through hole 212 for insertion of the endotracheal tube t in communication with the through hole 111. A lumen 301 through which the endotracheal tube t can be inserted is formed by the through hole 212 and the through hole 111 described above.
  • the surface shape around the opening 211 of the mask member 21 is preferably formed to correspond to the shape around the larynx opening in the pharynx of the mouse, whereby the mask member 21 is stably seated in the larynx opening and the trachea
  • the lumen 301 of the auxiliary tool 1 can be reliably conducted.
  • each part of the mask member 21 (see FIG. 3) are usually 2 mm to 11 mm in total length L1, 2 mm to 5 mm in maximum width L2, and 2 mm to 6 mm in maximum height L3 in consideration of the shape of the pharynx and larynx opening. is there.
  • the opening 211 of the mask member 21 usually has a total length L5 of 4 mm to 6 mm and a maximum width L6 of 1 mm to 2 mm in consideration of the shape of the larynx opening.
  • the shape of the tip end portion of the mask member 21 is preferably a curved shape (a shape in which the tip end portion of the mask member 21 is not sharp when viewed from any direction, see FIGS. 1 and 2). As described above, since the shape of the tip of the mask member 21 is a curved shape, it is possible to reduce the stimulation on the sensory receptor of the mouse accompanying the contact of the mask member 21 (the tip of the mask member 21). For example, it is possible to suppress the occurrence of respiratory disorder and the like due to reflection.
  • a resin material etc. are mentioned, for example.
  • a silicone resin and a urethane resin are preferable, and a silicone resin is more preferable, from the viewpoint of reducing the irritation due to the contact with the mucous membrane of the pharyngeal inner wall.
  • the resin material discharged by the discharge device is applied to the tip of the shaft main body 110 and room temperature or heat
  • a method of forming by curing, a method of mounting the tip of the shaft body 110 on a die (not shown), filling the resin material before curing around the opening of the shaft body 110 and thermally curing the same It can be adopted.
  • the delivery direction a2 of the endotracheal tube t through the opening 211 is such that the delivery direction a2 of the endotracheal tube t is an acute angle (delivery angle ⁇ ⁇ 90 °, see FIG. 3) with respect to the tip direction a1 of the shaft member 11. Is formed.
  • the endotracheal tube t delivered from the opening part 211 can be orient
  • the delivery direction a2 of the endotracheal tube t through the opening 211 is preferably 4 ° or more and 30 ° or less, more preferably 5 ° or more and 25 ° or less with respect to the distal end direction a1 of the shaft member 11 Preferably, it is more preferably 6 ° or more and 22 ° or less.
  • the delivery direction a2 of the endotracheal tube t can be more accurately directed to the trachea direction, and the endotracheal tube t can be more reliably intubated into the trachea of the mouse.
  • the configuration for making the delivery direction a2 of the endotracheal tube t acute is not particularly limited.
  • the mask member 21 has a deflection portion 31 that deflects the advancing direction of the endotracheal tube t. It may be done.
  • a raised portion 311 or the like formed on the inner periphery in the vicinity of the opening 211 of the mask member 21 can be employed as the deflection unit 31.
  • the deflection unit 31 may be integral with or separate from the mask member 21.
  • the auxiliary tool 1 is configured such that the advancing direction of the endotracheal tube t which has passed through the through hole 111 is the shaft member 11 by contact with the deflecting portion 31.
  • the endotracheal tube t can be intubated into the trachea of the mouse with a simple configuration.
  • the delivery direction a2 of the endotracheal tube t is a tip direction Since the endotracheal tube t can be inserted into the trachea via the larynx without entering the esophagus because it has an acute angle with respect to a1, the endotracheal tube t can be used without using an expensive instrument such as an endoscope.
  • the tube can be intubated into the trachea of the mouse quickly and easily.
  • the shaft member 11 has the marker 120, the opening 211 of the mask member 21 can be accurately aligned with the laryngeal opening of the mouse.
  • FIG. 4 is a schematic cross-sectional view showing a second embodiment of the present invention.
  • assistant tool 2 is roughly comprised by the shaft member 11, the mask member 21, and the pipe member 52, as shown in FIG.
  • the present embodiment differs from the first embodiment in that the pipe member 52 is provided.
  • symbol is attached
  • the description in the section of ⁇ Method for intubating endotracheal tube for mice> described later is also used for the mode of use of the auxiliary tool 2.
  • the pipe member 52 is a curved member which is formed so as to allow the endotracheal tube t to be inserted therein, communicates with the through hole 111 of the shaft member 11, and deflects the advancing direction of the endotracheal tube t.
  • the pipe member 52 has its proximal end inserted into the through hole 111 of the shaft body 110 and is fixed so that the outer periphery of the inserted pipe member 52 and the inner periphery of the shaft body 110 are in close contact. . Further, as shown in FIG. 5, the pipe member 52 is disposed such that the opening end surface 522 at the tip end faces the opening 211 of the mask member 21.
  • the pipe member 52 has a substantially arc-like curved shape in the middle between the distal end and the proximal end such that the delivery direction a2 of the endotracheal tube t from the opening 211 is acute at the distal direction a1. Is formed.
  • the through hole 521 of the pipe member 52 and the through hole 111 form a lumen 302 through which the endotracheal tube t can be inserted.
  • stainless steel As a material which comprises pipe member 52, stainless steel, a titanium alloy, a cobalt chromium alloy etc. are mentioned, for example. Among them, stainless steel is preferable as a material to be configured with the pipe member 52, and SUS304 is more preferable, from the viewpoint of ease of preparation.
  • the front end direction a1 of the shaft member 11 is carried out so that the advancing direction of the endotracheal tube t which passed through the inside of the through-hole 111 may follow the curve shape of the pipe member 52.
  • the endotracheal tube t can be intubated into the trachea of the mouse with a simple configuration.
  • Third Embodiment 6 and 7 are a schematic plan view and a schematic side view, respectively, showing a third embodiment of the present invention.
  • the auxiliary tool 3 (3 m1 to 3 m10) is roughly configured by the shaft member 11, the mask member 21 and the projecting member 63, as shown in FIGS.
  • the present embodiment differs from the first embodiment in that a projecting member 63 is provided.
  • symbol is attached
  • the description in the section of ⁇ Method of intubating endotracheal tube for mouse> described later is also used for the usage mode of the auxiliary tool 3.
  • the projecting member 63 is a member whose tip is located in the middle of the shaft body 110 in the axial direction of the shaft member 11 and protrudes from the outer peripheral surface of the shaft body 110.
  • a part of the projecting member 63 may be fixed to the outer periphery of the shaft body 110 using an adhesive or the like, and may be formed to extend outward of the shaft body 110.
  • the specific shape of the projecting member 63 is, for example, a triangular shape (see the projecting member 63m1 of FIG. 6A) or a rectangular shape (the projecting member 63m2 of FIG. 6B) as a shape in plan view. See the following), in a shape that changes gradually in width (see the projection member 63m3 in FIG. 6 (c)), those projecting only on one side of the shaft body 110 (see the projection member 63m4 in FIG. 6 (d)), etc.
  • a shape in a side view for example, a shape extending radially from the shaft body 110 (see the projecting members 63m5 to 63m8 in FIGS.
  • FIGS. 7A to 7D a shape circumscribing the shaft body 110 (see FIGS. 7A to 7D) 7 (e) and 7 (f) can be adopted.
  • the shape of the planar view and the shape of the side view exemplified above may be combined arbitrarily within the possible range.
  • the projecting members 63 are preferably arranged to be symmetrical with respect to an imaginary plane b passing through the axis of the shaft member 11 and the center of the opening 211 (FIGS. 6A to 6C (c). 7 (a), 7 (b) and 7 (d) to 7 (f)).
  • the maximum width of the projecting member 63 in the direction orthogonal to the axis of the shaft member 11 is preferably larger than the width of the tip of the projecting member 63 (see FIGS. 6A and 6C). .
  • the said auxiliary tool 3 can be smoothly inserted in the oral cavity of a mouse
  • the projecting member 63 is preferably formed in a flat shape (substantially flat shape) as a whole (see FIGS. 7A to 7C, and FIGS. 7E and 7F). .
  • the projecting member 63 can be made to correspond to (follow along) the flat oral cavity shape of the cross section which is the feature of the mouse, and the mask member 21 can be seated on the pharyngeal opening more stably.
  • the said auxiliary tool 3 is the said structure, it can be stably seated in the oral cavity of a mouse
  • the method of intubating a mouse endotracheal tube is a method of intubating a mouse endotracheal tube for guiding the endotracheal tube into the trachea of a mouse via the larynx, and A first step of inserting the tip of the assisting tool into the pharynx of the mouse, a second step of bringing the mask member into contact with the periphery of the laryngeal opening in the pharynx after the first step, and And a third step of intubating the endotracheal tube into the trachea of the mouse through the aid.
  • the auxiliary tool 1 is inserted into the throat m3 of the mouse m from the distal direction of the auxiliary tool 1. Specifically, as shown in FIG. 8A, after inserting the assisting tool 1 into the oral cavity m2 of the mouse m, if the assisting tool 1 has the marker 120, for example, the marker 120 is the mouse m Push the larynx m3 until the position of the incisor m1 is reached, or if the marker 120 is not provided, push the laryngeal m3 until the pressing resistance of the auxiliary 1 changes (increases), the auxiliary 1 is put in the proper position insert.
  • the second step In the second step, after performing the above-mentioned first step, as shown in FIG. 8 (b), the mask member 21 is moved in the direction of the larynx m3, and the surface of the mask member 21 is around the larynx opening m5 in the pharynx m3. Abut on. At this time, at least a part of the mask member 21 may simply be in contact with the periphery of the larynx opening m5, and it is not necessary to completely cover the periphery of the larynx opening m5.
  • the surface of the epiglottis m6 be supported such that the epiglottis m6 does not close the laryngeal opening m5 by bringing the surface of the mask member 21 into contact with the epiglottis m6. Thereby, the insertion of the endotracheal tube t described later into the trachea m7 can be performed more smoothly.
  • the endotracheal tube t is intubated into the trachea m7 of the mouse m through the auxiliary tool 1. Specifically, an endotracheal tube t is inserted from the proximal end opening 112 of the shaft member 11, and the endotracheal tube t is pushed forward in the order of the through hole 111 and the through hole 212 (see FIG. 8 (c)). The distal end of the tube t is intubated into the trachea m7 via the larynx m4 (see FIG. 8 (d)).
  • desired treatment such as supply of anesthetic gas or promotion of respiration is performed using, for example, a respirator connected to the endotracheal tube t.
  • desired treatment such as supply of anesthetic gas or promotion of respiration is performed using, for example, a respirator connected to the endotracheal tube t.
  • the endotracheal tube t and the aid 1 are sequentially pulled out of the larynx m4, the pharynx m3 and the oral cavity m2 of the mouse m.
  • the intubation method has the above configuration, when the endotracheal tube t for a mouse is intubated in the trachea m7 using the auxiliary tool 1, the delivery direction a2 of the endotracheal tube t is the distal direction a1.
  • the endotracheal tube t can be intubated to the trachea m7 through the larynx m4 without entering the esophagus m8 because it has an acute angle with respect to the The tube t can be intubated in the trachea m7 of the mouse m reliably, quickly and easily.
  • the first embodiment describes the auxiliary tool 1 having the deflecting portion 31 in the first embodiment, and the auxiliary tool 2 including the pipe member 52 in the second embodiment, the endotracheal tube through the opening 211
  • the delivery direction a2 of t is formed to be an acute angle with respect to the distal direction a1 of the shaft member 11, an aid other than the aids 1 and 2 may be used.
  • the aids 1 to 3 including the shaft member 11 having the marker 120 have been described, but the aid may not have the marker.
  • the auxiliary implement used in the intubation method of the present invention is the auxiliary tool of any aspect according to the present invention.
  • the auxiliary tool 3 can also be used.

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Endoscopes (AREA)
  • Surgical Instruments (AREA)
  • Prostheses (AREA)

Abstract

Le but de la présente invention est de produire un instrument auxiliaire permettant d'insérer de manière fiable une sonde endotrachéale, rapidement et facilement, dans la trachée d'une souris sans utiliser un instrument onéreux, et de fournir un procédé d'insertion d'une sonde endotrachéale pour une souris utilisant ledit instrument. Un instrument auxiliaire (1) de la présente invention comprend : un arbre (11) pourvu d'un corps (110) à l'intérieur duquel est ménagé un trou traversant (111) dans lequel une sonde endotrachéale t doit être insérée; et un masque (21) qui est relié à une extrémité de l'arbre (11) et qui doit venir en butée contre au moins une partie de la périphérie d'ouverture de larynx dans le pharynx. Le masque (21) présente une ouverture (211) communiquant avec le trou traversant (111) de l'arbre (11), et est formé de sorte qu'une direction de distribution a2 de la sonde endotrachéale t dans l'ouverture (211) se trouve à un angle aigu par rapport à la direction d'extrémité avant a1 de l'arbre (11).
PCT/JP2019/000843 2018-01-17 2019-01-15 Instrument auxiliaire et procédé d'insertion de tube endotrachéal pour souris utilisant ledit instrument WO2019142757A1 (fr)

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JP2019566454A JP7309199B2 (ja) 2018-01-17 2019-01-15 補助具、およびこれを用いたマウス用気管内チューブの挿管方法

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JP2018005343 2018-01-17
JP2018-005343 2018-01-17
JP2018-166126 2018-09-05
JP2018166126 2018-09-05

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005535397A (ja) * 2002-08-14 2005-11-24 ナジール，ムハマド，アスラム 改良型エアウェイ装置
JP2009072465A (ja) * 2007-09-21 2009-04-09 Univ Of Occupational & Environmental Health Japan 上気道エアウェイ
JP2015531300A (ja) * 2012-10-08 2015-11-02 ザ クリーブランド クリニック ファウンデーションＴｈｅ Ｃｌｅｖｅｌａｎｄ ＣｌｉｎｉｃＦｏｕｎｄａｔｉｏｎ 対象を換気するための可逆的気道デバイスおよび関連する方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005535397A (ja) * 2002-08-14 2005-11-24 ナジール，ムハマド，アスラム 改良型エアウェイ装置
JP2009072465A (ja) * 2007-09-21 2009-04-09 Univ Of Occupational & Environmental Health Japan 上気道エアウェイ
JP2015531300A (ja) * 2012-10-08 2015-11-02 ザ クリーブランド クリニック ファウンデーションＴｈｅ Ｃｌｅｖｅｌａｎｄ ＣｌｉｎｉｃＦｏｕｎｄａｔｉｏｎ 対象を換気するための可逆的気道デバイスおよび関連する方法

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