WO2019117585A3 - 결핵진단용 조성물 및 광학적 특성 변화에 기반한 결핵 진단방법 - Google Patents

결핵진단용 조성물 및 광학적 특성 변화에 기반한 결핵 진단방법 Download PDF

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Publication number
WO2019117585A3
WO2019117585A3 PCT/KR2018/015675 KR2018015675W WO2019117585A3 WO 2019117585 A3 WO2019117585 A3 WO 2019117585A3 KR 2018015675 W KR2018015675 W KR 2018015675W WO 2019117585 A3 WO2019117585 A3 WO 2019117585A3
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Prior art keywords
diagnosing tuberculosis
change
optical characteristics
basis
tuberculosis
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PCT/KR2018/015675
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English (en)
French (fr)
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WO2019117585A2 (ko
Inventor
이진우
전선아
박찬영
김은주
Original Assignee
주식회사 딕스젠
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Priority claimed from KR1020180158404A external-priority patent/KR102098030B1/ko
Application filed by 주식회사 딕스젠 filed Critical 주식회사 딕스젠
Priority to CN201880079556.0A priority Critical patent/CN111465856A/zh
Publication of WO2019117585A2 publication Critical patent/WO2019117585A2/ko
Publication of WO2019117585A3 publication Critical patent/WO2019117585A3/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

본 발명은 결핵진단용 조성물 및 광학적 특성 변화에 기반한 결핵 진단방법에 관한 것이다. 상기 결핵 진단방법은 (a) 형광나노물질-항체 복합체와 형광나노물질-항체 복합체 또는 (b) 형광나노물질-항체 복합체와 금속나노입자-항체 복합체의 광학적 특성 변화에 기반한 것을 특징으로 한다. 본 발명에 따른 광학적 특성의 변화에 기반한 결핵 진단방법은 금속나노입자 및 형광나노물질의 형광세기 변화를 이용하므로 낮은 검출한계를 갖는 결핵을 신속하고, 정확하게 측정할 수 있다.
PCT/KR2018/015675 2017-12-11 2018-12-11 결핵진단용 조성물 및 광학적 특성 변화에 기반한 결핵 진단방법 WO2019117585A2 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201880079556.0A CN111465856A (zh) 2017-12-11 2018-12-11 结核诊断用组合物以及基于光学特性变化的结核诊断方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20170169012 2017-12-11
KR10-2017-0169012 2017-12-11
KR10-2018-0158404 2018-12-10
KR1020180158404A KR102098030B1 (ko) 2017-12-11 2018-12-10 결핵진단용 조성물 및 광학적 특성 변화에 기반한 결핵 진단방법

Publications (2)

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WO2019117585A2 WO2019117585A2 (ko) 2019-06-20
WO2019117585A3 true WO2019117585A3 (ko) 2019-08-01

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Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111273022B (zh) * 2020-02-06 2023-11-28 上海市胸科医院 一种基于纳米金-石墨烯量子点的肌钙蛋白浓度的检测方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101169418B1 (ko) * 2010-05-11 2012-07-27 부산대학교 산학협력단 면역측정법을 위한 자기영동 나노바이오센서
EP2629095A1 (en) * 2012-02-17 2013-08-21 Biosure R & T Cell Co. Detection of mycobacterial protein targets using quantum dots (QDs) and immunomagnetic seperation
WO2015122391A1 (ja) * 2014-02-13 2015-08-20 国立大学法人静岡大学 量子ドット蛍光増強免疫測定法
KR101631054B1 (ko) * 2015-12-31 2016-06-16 중앙대학교 산학협력단 마이코박테리아 유래 CFP-10 또는 Ag85B에 특이적으로 결합하는 항체 또는 그의 항원 결합 단편
KR20170115211A (ko) * 2016-04-06 2017-10-17 중앙대학교 산학협력단 우결핵 진단용 키트 및 이를 이용한 우결핵 진단 방법

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101169418B1 (ko) * 2010-05-11 2012-07-27 부산대학교 산학협력단 면역측정법을 위한 자기영동 나노바이오센서
EP2629095A1 (en) * 2012-02-17 2013-08-21 Biosure R & T Cell Co. Detection of mycobacterial protein targets using quantum dots (QDs) and immunomagnetic seperation
WO2015122391A1 (ja) * 2014-02-13 2015-08-20 国立大学法人静岡大学 量子ドット蛍光増強免疫測定法
KR101631054B1 (ko) * 2015-12-31 2016-06-16 중앙대학교 산학협력단 마이코박테리아 유래 CFP-10 또는 Ag85B에 특이적으로 결합하는 항체 또는 그의 항원 결합 단편
KR20170115211A (ko) * 2016-04-06 2017-10-17 중앙대학교 산학협력단 우결핵 진단용 키트 및 이를 이용한 우결핵 진단 방법

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KIM, E. J. ET AL.: "An easy and sensitive sandwich assay for detection of Mycobacterium tuberculosis Ag85B antigen using quantum dots and gold nanorods", BIOSENS. BIOELECTRON, vol. 87, 12 August 2016 (2016-08-12), pages 150 - 156, XP055629770 *

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