WO2019109403A1 - Système de sphincter anal artificiel bionique implanté in situ ayant une structure de bras oscillant indépendante - Google Patents

Système de sphincter anal artificiel bionique implanté in situ ayant une structure de bras oscillant indépendante Download PDF

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Publication number
WO2019109403A1
WO2019109403A1 PCT/CN2017/117895 CN2017117895W WO2019109403A1 WO 2019109403 A1 WO2019109403 A1 WO 2019109403A1 CN 2017117895 W CN2017117895 W CN 2017117895W WO 2019109403 A1 WO2019109403 A1 WO 2019109403A1
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WO
WIPO (PCT)
Prior art keywords
rotating shaft
anal sphincter
ring mechanism
artificial anal
hall element
Prior art date
Application number
PCT/CN2017/117895
Other languages
English (en)
Chinese (zh)
Inventor
韩玎
颜国正
赵凯
王志武
周泽润
吴昌建
刘大生
Original Assignee
上海交通大学
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Filing date
Publication date
Application filed by 上海交通大学 filed Critical 上海交通大学
Priority to US16/963,819 priority Critical patent/US20210052365A1/en
Publication of WO2019109403A1 publication Critical patent/WO2019109403A1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/08Muscles; Tendons; Ligaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0008Temperature signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/03Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
    • A61B5/036Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs by means introduced into body tracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/42Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4222Evaluating particular parts, e.g. particular organs
    • A61B5/4255Intestines, colon or appendix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4851Prosthesis assessment or monitoring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/0004Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse
    • A61F2/0031Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse for constricting the lumen; Support slings for the urethra
    • A61F2/0036Closure means for urethra or rectum, i.e. anti-incontinence devices or support slings against pelvic prolapse for constricting the lumen; Support slings for the urethra implantable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02Operational features
    • A61B2560/0204Operational features of power management
    • A61B2560/0214Operational features of power management of power generation or supply
    • A61B2560/0219Operational features of power management of power generation or supply of externally powered implanted units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0223Magnetic field sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247Pressure sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/48Operating or control means, e.g. from outside the body, control of sphincters
    • A61F2/482Electrical means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/08Muscles; Tendons; Ligaments
    • A61F2002/0894Muscles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0001Means for transferring electromagnetic energy to implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0004Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof adjustable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02JCIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J2310/00The network for supplying or distributing electric power characterised by its spatial reach or by the load
    • H02J2310/10The network having a local or delimited stationary reach
    • H02J2310/20The network being internal to a load
    • H02J2310/23The load being a medical device, a medical implant, or a life supporting device
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02JCIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J50/00Circuit arrangements or systems for wireless supply or distribution of electric power
    • HELECTRICITY
    • H02GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02JCIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J50/00Circuit arrangements or systems for wireless supply or distribution of electric power
    • H02J50/10Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling

Definitions

  • the invention relates to a technology in the field of medical instruments, in particular to an in situ implantation bionic artificial anal sphincter system with an independent swing arm structure.
  • the artificial anal sphincter prosthesis simulates the physiological function of the normal external anal sphincter.
  • the pressure sensor senses the rectal pressure, and the control system is used to realize rectal sensation remodeling, and the self-controlled defecation is realized, thereby treating fecal incontinence.
  • the existing fully enclosed anal sphincter prosthesis mechanism is generally complicated, and the number of parts is large, resulting in a large sphincter weight, which will bring biocompatibility and safety problems after implantation in the body; the commonly used Hall switch installation position Difficulties in adjustment make it difficult to guarantee the normal working interval of the Central, affecting the normal opening or closing of the sphincter system.
  • these prosthesis mechanisms generally have more central and accessory components, and assembly difficulties lead to lower assembly accuracy affecting the transmission effect, which in turn enables the sphincter system to Uneven consumption affects the normal operation of the system; some activities in the central ring are difficult to guarantee, and there are problems such as security.
  • the present invention is directed to the above-mentioned deficiencies of the prior art, and proposes an in situ implanted bionic artificial anal sphincter system with an independent swing arm structure.
  • the present invention uses a planetary gear reducer, the structure is simpler and smaller, and the risk of surgical transplantation is reduced;
  • the central structure of the rotating shaft is simple, which reduces the difficulty of installation;
  • the Hall switch is arranged in the upper ring chamber to facilitate the arrangement of the wires;
  • the external gear meshing transmission torque is simple and reliable.
  • the invention comprises: an energy transmission control unit and a sphincter prosthesis unit, the energy transmission control unit comprises a main control module and a transcutaneous wireless energy transmission module, the sphincter prosthesis unit comprises: a wireless energy receiving module, a micro power source, a sensor, an execution unit and From the control module, wherein: the main control module is connected to the control module through wireless communication and transmits the manipulation command signal to the body from the control module, and the transcutaneous wireless energy transmission module is connected to the wireless energy receiving module through electromagnetic coupling, and the internal receiving module and the micro The power source is connected, and the energy is transmitted to the micro power source through the body receiving module, and the function is charged to the micro power source.
  • the sensor and the actuator are connected with the slave control module and transmit the intestinal intestinal pressure, the temperature information and the position information of the actuator.
  • the control module passes the in-vivo information to the external control module connected to it.
  • the execution unit includes a fixed connection and an opposite arrangement of upper and lower ring mechanisms and a middle ring mechanism rotatably disposed between the upper ring mechanism and the lower ring mechanism, wherein: the fixed connection passes through the two ends and the upper ring mechanism and the lower ring mechanism respectively
  • the connected drive mechanism realizes that the middle ring mechanism is rotated by being connected to an independent rotating shaft between the upper and lower ring mechanisms, at least one end of the rotating shaft is meshed with the driving mechanism, and the torque outputted by the driving mechanism is driven by the rotating shaft to realize the middle ring.
  • the driving mechanism includes: a motor with a reduction box disposed in the motor sleeve, wherein: the output shaft of the reduction box is coupled to at least one end of the rotating shaft through gear engagement.
  • the middle ring mechanism is fixedly connected with the rotating shaft, and the magnet supporting member rotating synchronously with the rotating shaft is provided with a magnet, and a gear element is arranged on the gear partition in the upper ring mechanism chamber, and the magnet is rotated to the Hall element.
  • the trigger generation limit signal controls the drive mechanism to stop working; when the drive mechanism reversely drives the middle ring mechanism to rotate in the opposite direction, the position is sensed by the position sensing of the Hall element. It is further preferred to further determine the exact position at which the central ring mechanism is located by providing two Hall elements.
  • the mechanism is simple, the number of parts is small, the weight of the mechanism is reduced, and the compatibility and safety after implantation in the body are strong;
  • the Hall element is placed in the upper ring mechanism and sealed by the sealing ring.
  • the installation position of the Hall switch is easy to adjust to ensure the normal operation of the Hall switch, thereby ensuring the normal opening or closing of the intestinal tract by the sphincter system;
  • the magnet matched with the Hall element is disposed in the magnet support member that rotates synchronously with the rotating shaft, and can adjust the position according to the opening angle required for swinging the middle ring;
  • the planetary gear reducer can reduce the overall size of the mechanism, and the motor sleeve not only fixes the motor reducer but also facilitates wiring;
  • the central mechanism is fixedly connected with the rotating shaft.
  • the relevant parts of the actuator can be modularly installed and finally integrated into the upper and lower ring mechanisms, which greatly shortens the assembly time.
  • the central mechanism uses a sealing ring for sealing and the active sealing is guaranteed.
  • Figure 1 is a schematic view of the artificial sphincter system of the present invention
  • FIG. 2a is a schematic view showing the overall structure of the sphincter prosthesis of the present invention
  • FIG. 2b is a schematic view showing the overall structure of the sphincter prosthesis of the present invention
  • Figure 3 is a schematic view showing the installation of the rotating shaft of the present invention.
  • Figure 4 is a schematic view showing the mounting structure of the Hall element of the present invention.
  • Figure 5a is a schematic view showing the mounting structure of the motor, the reduction box and the sleeve of the present invention
  • Figure 5b is a side view of the mounting structure of the motor, the reduction box and the sleeve of the present invention
  • FIG. 6a is a schematic view showing the installation structure of the independent middle ring mechanism of the present invention
  • FIG. 6b is a side view of the installation structure of the independent middle ring mechanism of the present invention
  • the embodiment includes: an energy sending control unit and a sphincter prosthesis unit, the energy sending control unit includes a main control module and a transcutaneous wireless energy sending module, and the sphincter prosthesis unit comprises: a wireless energy receiving module, and a micro Power supply, sensor, execution unit and slave control module, wherein: the main control module is connected to the control module through wireless communication and transmits the manipulation command signal to the body from the control module, and the percutaneous wireless energy transmission module passes the electromagnetic coupling and the wireless energy receiving module.
  • the body receiving module is connected to the micro power source, and the energy is transmitted to the micro power source through the body receiving module, and the function is charged to the micro power source.
  • the execution unit includes: an upper ring mechanism a, a lower ring mechanism b, and a middle ring mechanism c, wherein: the upper ring mechanism a is connected to the upper end of the driving mechanism d through the upper ring support member 9, and the lower ring
  • the mechanism b is connected to the lower end of the driving mechanism d through the lower ring support member 16
  • the movable central ring mechanism c is fixedly connected to the independent rotating shaft 13
  • the upper end of the motor 12 in the motor sleeve 11 of the driving mechanism d is provided with a planetary gear reduction box 10
  • the torque is transmitted to the independent rotating shaft 13 through the two-stage transmission gear train 5, and the swing arm movement of the middle ring is realized, and the swing angle is restricted by the Hall switch.
  • the rotating shaft 13 is sequentially provided with a transmission gear train 5, a magnet support member 6, and an upper bearing sleeve cover 7 and rotates synchronously with the rotating shaft 13, wherein: the position hole 22 of the magnet support member 6 A magnet is provided, and the transmission gear train 5 is connected to the output shaft of the reduction gearbox 10 of the drive mechanism d.
  • the upper end of the rotating shaft 13 is respectively provided with an upper bearing sleeve 8 and a lower bearing sleeve 17 to achieve a rotational connection with the upper ring mechanism a and the lower ring mechanism b; the upper end of the rotating shaft 13
  • the D-shaped structure is rotated in synchronization with the transmission gear train 5 to transmit torque to the center ring mechanism c.
  • the bottom of the upper ring mechanism a is provided with a gear partition 4, and the magnet support 6 of the rotating shaft 13 is movably nested in the gear partition 4.
  • One side of the gear partition 4 is provided with a position chamber 23 for mounting a Hall element.
  • the Hall element switch is formed by matching with the magnet at the position hole 22 to limit the center ring mechanism: when the middle ring mechanism rotates, the magnet in the magnet position hole 6 is rotated together, when the magnet rotates to When the position of the Hall element coincides, the Hall element generates a limit signal that prevents the drive mechanism from continuing to rotate, thereby achieving the limit of the center mechanism.
  • the design position of the magnet mounting position hole 6 and the Hall element housing 23 is more open, which is convenient for adjusting the positioning.
  • the reduction gear box 10 of the driving mechanism d is disposed above the motor 12 and nested in the motor sleeve 11.
  • the motor sleeve 11 is provided with an arcuate groove 24 corresponding to the upper ring sensor and
  • the Hall element is connected to the routing channel of the lower loop control communication module 20.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Hematology (AREA)
  • Prostheses (AREA)

Abstract

Cette invention concerne un système de sphincter anal artificiel implanté in situ ayant une structure de bras oscillant indépendante, comprenant : une unité de commande d'envoi d'énergie et une unité de prothèse de sphincter, où l'unité de commande d'envoi d'énergie comprend un module de commande principal et un module d'envoi d'énergie sans fil percutané, et l'unité de prothèse de sphincter comprend un module de réception d'énergie sans fil, une micro-source d'énergie, un capteur, une unité d'exécution et un module de commande esclave. Le système de sphincter anal artificiel selon l'invention a une structure globale plus simple, plus petite et plus compacte, qui réduit les risques de transplantation ; une bague intermédiaire (c) pourvue d'un arbre rotatif indépendant (13), de structure simple, qui réduit la difficulté de montage ; un élément à effet Hall logé dans un compartiment (23), qui facilite le câblage ; et un engrenage externe à vitesse engagée pour la transmission, ayant un couple simple et une fiabilité élevée.
PCT/CN2017/117895 2017-12-05 2017-12-22 Système de sphincter anal artificiel bionique implanté in situ ayant une structure de bras oscillant indépendante WO2019109403A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US16/963,819 US20210052365A1 (en) 2017-12-05 2017-12-22 In situ implanted bionic artificial anal sphincter system having independent swing arm structure

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201711264462.4 2017-12-05
CN201711264462.4A CN107928840B (zh) 2017-12-05 2017-12-05 具有独立摆臂结构的原位植入仿生人工肛门括约肌假体

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WO2019109403A1 true WO2019109403A1 (fr) 2019-06-13

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US (1) US20210052365A1 (fr)
CN (1) CN107928840B (fr)
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CN114962898A (zh) * 2022-05-30 2022-08-30 广西南宁市绿滋宝农业科技有限公司 一种用于生猪养殖的监控检测系统

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CN109223251A (zh) * 2018-11-07 2019-01-18 上海交通大学 用于仿耻骨人工肛门括约肌假体的精密减速器
CN109223252A (zh) * 2018-11-07 2019-01-18 上海交通大学 仿耻骨人工肛门括约肌假体动力传动及限位装置
CN109875724B (zh) * 2019-03-29 2021-06-22 上海交通大学 双轴驱动封闭夹持装置
CN109875731B (zh) * 2019-04-03 2021-08-27 上海交通大学 接触式人工肛门括约肌假体限位保护开关装置
CN111973314B (zh) * 2019-05-21 2023-08-01 上海交通大学 三环仿生人造肛门括约肌防组织向内增生的防护套
CN112869911B (zh) * 2020-12-18 2023-07-21 中山大学附属第六医院 一种植入式人工肛门

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CN105030194A (zh) * 2015-04-22 2015-11-11 上海交通大学 基于柔性压力传感器与红外探测的肠道内容物检测系统及方法
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CN107157619A (zh) * 2017-06-01 2017-09-15 上海交通大学 密封壳保护型肛门括约肌假体

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