WO2019029029A1 - 一种防晒组合物、其制备方法、防晒喷雾剂及其制备方法 - Google Patents

一种防晒组合物、其制备方法、防晒喷雾剂及其制备方法 Download PDF

Info

Publication number
WO2019029029A1
WO2019029029A1 PCT/CN2017/109784 CN2017109784W WO2019029029A1 WO 2019029029 A1 WO2019029029 A1 WO 2019029029A1 CN 2017109784 W CN2017109784 W CN 2017109784W WO 2019029029 A1 WO2019029029 A1 WO 2019029029A1
Authority
WO
WIPO (PCT)
Prior art keywords
sunscreen
extract
sunscreen composition
spray
mixed
Prior art date
Application number
PCT/CN2017/109784
Other languages
English (en)
French (fr)
Inventor
杨志喜
罗东勋
Original Assignee
广州无添加主义化妆品有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 广州无添加主义化妆品有限公司 filed Critical 广州无添加主义化妆品有限公司
Publication of WO2019029029A1 publication Critical patent/WO2019029029A1/zh

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/046—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations

Definitions

  • the invention relates to the field of cosmetics, and in particular to a sunscreen composition, a preparation method thereof, a sunscreen spray and a preparation method thereof.
  • the existing physical sunscreens contain physical sunscreen components such as titanium dioxide and/or zinc oxide. These fine particles can form a barrier layer on the skin surface and protect the skin by reflecting and scattering ultraviolet rays. The transparency is easy to occur when the surface of the skin is deposited as a white layer and falls off. Excessive use may cause clogging of the pores.
  • a first object of the present invention is to provide a sunscreen composition which is a natural sunscreen composition excellent in properties and has the advantages of good sunscreen effect and good lightproof effect.
  • a second object of the present invention is to provide a sunscreen spray which is prepared from the above sunscreen composition and which does not contain a physical sunscreen component, has the advantages of not clogging pores and causing allergy, and is a safe sunscreen product. .
  • the invention provides a preparation method of a sunscreen composition, comprising:
  • the yellow extract is extracted to obtain a first extract, and a mixture of peony root bark, Rhodiola and Artemisia annua L. is extracted to obtain a second extract, and the first extract and the second extract are mixed.
  • the mass ratio of the above-mentioned scutellaria, peony bark, Rhodiola and Artemisia annua L. is 1.5 to 3.5: 1.5 to 2.5:1 to 2.3:2 to 4.
  • the above-mentioned smashed to 45-60 mesh xanthine and 0.9-2.9 vt% acetic acid solution are mixed at a mass ratio of 1:15 to 25, at a temperature of 38 to 49 ° C.
  • the extract is extracted with a power of 40 to 60 W for 25 to 35 minutes, and the extract product of the astragalus is filtered to obtain a first filtrate, and the first filtrate is decolorized using activated carbon to obtain a first extract.
  • the mixture pulverized to 45 to 60 mesh and 60 to 95 vt% ethanol are mixed at a mass ratio of 1:15 to 25, and at a temperature of 38 to 49 ° C and 60. Extraction was carried out at a power of -80 W for 25 to 35 minutes, and the extracted product of the mixture was filtered to obtain a second filtrate, and the second filtrate was decolorized using activated carbon to obtain a second extract.
  • the present invention provides a sunscreen composition prepared according to the above-described method for preparing a sunscreen composition.
  • the invention provides a sunscreen spray comprising:
  • the invention provides a preparation method of a sunscreen spray, comprising:
  • the above sunscreen composition, aloe extract, panthenol and base are mixed at a temperature of 40 to 50 °C.
  • the cosmetic base is mixed with water having a temperature of 60 to 80 ° C and maintained at a temperature of 95 to 100 ° C for 30 to 40 minutes to obtain a base.
  • butanediol, glycerin, betaine, dipotassium glycyrrhizinate and sodium hyaluronate are mixed to provide a cosmetic base.
  • the method further comprises packaging the sunscreen spray using a binary package.
  • the preparation method of the sunscreen composition of the embodiment of the invention obtains the first extract by extracting the astragalus, extracts the mixture of peony root bark, Rhodiola and Artemisia annua L. to obtain a second extract, and the first extract and the first extract
  • the sunscreen composition can be prepared quickly by mixing the second extract.
  • the sunscreen composition of the embodiment of the invention is a natural sunscreen composition with excellent properties, good sunscreen effect and good lightproof effect, high ultraviolet absorption intensity and strong absorption in the wavelength range of 270-400 nm. At the same time, it has the effect of eliminating free radicals generated by ultraviolet radiation of the skin.
  • the sunscreen spray of the embodiment of the invention uses the extracts of astragalus, peony root bark, Rhodiola and Artemisia annua as the sunscreen active ingredient, has the advantages of not blocking pores and not causing allergies, and is a safe sunscreen product. . It has the characteristics of low irritation, few side effects and safety and reliability, which can avoid the stimulation of human skin and the occurrence of allergies. Moreover, sunscreen sprays can effectively solve problems such as dermatitis, allergies or phototoxic reactions.
  • the preparation method of the sunscreen spray according to the embodiment of the present invention is prepared by using the above sunscreen composition as an active ingredient.
  • FIG. 1 is a schematic diagram of a binary package structure provided by the present invention.
  • FIG. 2 is a schematic structural view of a can body provided by the present invention.
  • FIG. 3 is a schematic structural view of an aerosol assembly provided by the present invention.
  • Icons 100-binary package; 110-tank; 111-can open; 120-balloon; 130-aerosol assembly; 131-cover; 132-spray tube; 133-valve assembly;
  • the sunscreen composition, the preparation method thereof, the sunscreen spray and the preparation method thereof according to the examples of the present invention are specifically described below.
  • a method of preparing a sunscreen composition comprising:
  • a first extract was prepared.
  • the prepared xanthine and acetic acid solution were mixed at a mass ratio of 1:15 to 25 and then extracted. Specifically, extraction is carried out at a temperature of 38 to 49 ° C and a power of 40 to 60 W for 25 to 35 minutes to obtain an extract product of astragalus.
  • the extract product of Astragalus membranaceus was filtered to obtain a first filtrate, and the first filtrate was decolorized using activated carbon to obtain a first extract.
  • the acetic acid solution is selected from 0.9 to 2.9 vt% acetic acid solution.
  • the Astragalus membranaceus is pulverized to 45-60 mesh before mixing with the acetic acid solution, and the extracting operation is carried out after obtaining the scutellaria powder. Through such an operation, the utilization of materials is effectively improved.
  • a second extract was prepared.
  • the prepared peony bark, Rhodiola and Artemisia annua are mixed to obtain a mixture, which is a mixture of peony root bark, Rhodiola and Artemisia annua.
  • the mixture and ethanol were mixed at a mass ratio of 1:15 to 25 and then extracted. Specifically, extraction is carried out at a temperature of 38 to 49 ° C and a power of 60 to 80 W for 25 to 35 minutes to obtain an extracted product of the mixture.
  • the extracted product of the mixture was filtered to obtain a second filtrate, and the second filtrate was decolorized using activated carbon to obtain a second extract.
  • ethanol is selected from 60 to 95 vt% of ethanol.
  • the mixture is pulverized to 45 to 60 mesh before mixing with the acetic acid solution to obtain a mixture, and then subjected to an extraction operation. Through such an operation, the utilization of materials is effectively improved.
  • the first extract and the second extract are mixed to obtain a sunscreen composition. That is, the preparation of the sunscreen composition is completed.
  • the extracts of Astragalus, Peony Root, Rhodiola and Artemisia annua include substances such as glycosides, polysaccharides, flavonoids and the like, and the above sunscreen composition is formed by the synergistic action of this substance.
  • the sunscreen composition prepared by the above preparation method of the sunscreen composition is a natural sunscreen composition with excellent properties, good sunscreen effect and good lightproof effect, high ultraviolet absorption intensity and wavelength of 270-400 nm. There is strong absorption in the range. At the same time, it has the effect of eliminating free radicals generated by ultraviolet radiation of the skin.
  • the sunscreen composition has a wide range of uses in skin repair, sun protection and treatment.
  • the sunscreen composition is a natural sunscreen component, which has the characteristics of low irritation, less side effects, safety and reliability, and can avoid the stimulation of human skin and the occurrence of allergies.
  • a sunscreen spray comprising: butylene glycol, glycerin, betaine, dipotassium glycyrrhizinate, sodium hyaluronate, the above sunscreen composition, aloe vera extract, panthenol and water.
  • the above components are mixed in the following ratios: 3 to 5 wt% of butanediol, 4 to 6 wt% of glycerin, 0.2 to 1.2 wt% of betaine, 0.3 to 1.3 wt% of dipotassium glycyrrhizinate, 0.05 to 0.2. Swt% sodium hyaluronate, 30 to 55 wt% of the above sunscreen composition, 3 to 5 wt% of aloe extract, 1 to 2.5 wt% of panthenol and the balance of water.
  • a method for preparing a sunscreen spray comprising:
  • the above raw material ratio of the sunscreen spray component, butanediol, glycerin, betaine, dipotassium glycyrrhizinate, sodium hyaluronate, the above sunscreen composition, aloe extract, panthenol and water are separately prepared.
  • Butanediol, glycerin, betaine, dipotassium glycyrrhizinate and sodium hyaluronate are mixed to obtain a cosmetic base.
  • the base material After mixing the cosmetic base and water at a temperature of 60 to 80 ° C, the base material is obtained by maintaining at a temperature of 95 to 100 ° C for 30 to 40 minutes.
  • the temperature of the water is 75 °C.
  • the sunscreen composition, aloe extract, panthenol and base are mixed at a temperature of 40 to 50 ° C to obtain a sunscreen spray.
  • the sunscreen spray is a sunscreen active ingredient of astragalus, peony root bark, Rhodiola and Artemisia annua L., which has the advantages of not blocking pores and causing allergies, and is a safe sunscreen product.
  • the sunscreen spray is packaged in a binary package 100.
  • the binary package 100 includes a can body 110 , an air bag 120 , an aerosol assembly 130 , and a spray head 140 .
  • the can body 110 has a can opening 111, and the can body 110 has compressed air therein.
  • the can body 110 may be an aluminum can or an iron can, and is not limited to other modes not listed in this embodiment.
  • the aerosol assembly 130 includes a cover 131, a spray tube 132, and a valve assembly 133.
  • the lid body 131 is closed to the tank opening 111 to realize that the aerosol assembly 130 is attached to the tank body 110.
  • the valve assembly 133 is disposed on the cover 131, and the spray tube 132 communicates with the valve assembly 133 and extends away from the can 110.
  • the air bag 120 is used to hold a sunscreen spray.
  • the open end of the air bag 120 is disposed at the valve assembly 133 to achieve closure of its open end.
  • the airbag 120 has a cylindrical shape.
  • the can 110 is evacuated and passed through a spray tube. 132 a sunscreen spray is introduced into the balloon 120, and the balloon is in an expanded state.
  • the shower head 140 is disposed on the spray tube 132, and the sunscreen spray in the airbag 120 can be ejected by pressing the shower head 140.
  • the binary package 100 may further include a cover (not shown) that is disposed on the showerhead 140 to prevent the showerhead 140 from being contaminated by the outside.
  • the binary packaging 100 it is possible to prevent the sunscreen spray from being secondaryly contaminated, avoiding the contact between the outside air and the spray interior material, causing the repairing sunscreen component to be oxidized and failing, and the yellowing and darkening of the sprayed body will be prolonged with the use of air oxidation time. phenomenon. That is, to avoid affecting the aesthetics of the sunscreen spray.
  • the binary package 100 can be sprayed out of the binary package 100 without the addition of a propellant.
  • the xanthine and 500 parts by weight of a 1.5 vt% acetic acid solution were mixed and heated to 40 ° C, and the active ingredient of the astragalus was extracted by ultrasonication to obtain an extract product of xanthine, specifically, the extraction temperature was 40 ° C, the extraction power was 55 W, and the extraction time was It is 30min.
  • the extract product of Astragalus membranaceus was filtered to obtain a first filtrate, and the first filtrate was decolorized using activated carbon to obtain a first extract.
  • the first extract and the second extract are mixed to obtain a sunscreen composition.
  • the components were prepared according to the following ratios: 4.2 wt% butanediol, 5.5 wt% glycerol, 0.3 wt% betaine, 0.3 wt% dipotassium glycyrrhizinate, 0.07 wt% sodium hyaluronate, 46 wt % sunscreen composition, 4.2% by weight of aloe vera extract, 1.1% by weight of panthenol and the balance of water.
  • Butanediol, glycerin, betaine, dipotassium glycyrrhizinate and sodium hyaluronate are mixed to obtain a cosmetic base.
  • the sunscreen composition, the aloe extract, the panthenol and the base are mixed and cooled while cooling to a temperature of 45 ° C to obtain a sunscreen spray.
  • the dried medicinal material was prepared: 30 parts by weight of xanthine, 18 parts by weight of peony bark, 20 parts by weight of Rhodiola and 32 parts by weight of Artemisia annua. Astragalus, peony root bark, Rhodiola and Artemisia annua were pulverized to 50 mesh, and used.
  • the xanthine and 540 parts by weight of a 1.5 vt% acetic acid solution were mixed and heated to 42 ° C, and the active ingredient of the astragalus was extracted by ultrasonic method to obtain an extract product of xanthine, specifically, the extraction temperature was 42 ° C, the extraction power was 50 W, and the extraction time was It is 28min.
  • the extract product of Astragalus membranaceus was filtered to obtain a first filtrate, and the first filtrate was decolorized using activated carbon to obtain a first extract.
  • the peony root bark, Rhodiola and Artemisia annua were mixed to obtain a mixture, and the mixture was mixed with 1400 parts by weight of 95 vt% ethanol and heated to 43 ° C, and the active ingredient of the mixture was extracted by ultrasonication to obtain an extract product of the mixture, specifically The extraction temperature was 43 ° C, the extraction power was 74 W, and the extraction time was 28 min.
  • the extracted product of the mixture was filtered to obtain a second filtrate, and the second filtrate was decolorized using activated carbon to obtain a second extract.
  • the first extract and the second extract are mixed to obtain a sunscreen composition.
  • the components were prepared according to the following ratios: 4.4 wt% of butanediol, 5.1 wt% of glycerin, 0.6 wt% of betaine, 0.8 wt% of dipotassium glycyrrhizinate, 0.1 wt% of sodium hyaluronate, 50 wt. % sunscreen composition, 4.6 wt% aloe extract, 2.1 wt% panthenol and the balance water.
  • Butanediol, glycerin, betaine, dipotassium glycyrrhizinate and sodium hyaluronate are mixed to obtain a cosmetic base.
  • the cosmetic base was mixed with water at a temperature of 75 ° C, it was heated to a temperature of 90 ° C and maintained at this temperature for 32 minutes to obtain a base.
  • the sunscreen composition, the aloe extract, the panthenol and the base are mixed and cooled while cooling to a temperature of 45 ° C to obtain a sunscreen spray.
  • the dried medicinal material was prepared: 30 parts by weight of xanthine, 23 parts by weight of peony root bark, 23 parts by weight of Rhodiola and 25 parts by weight of Artemisia annua.
  • the scutellaria, peony bark, Rhodiola and Artemisia annua were pulverized to 60 mesh, and used.
  • the active ingredient obtained the extract product of astragalus, specifically, the extraction temperature was 47 ° C, the extraction power was 50 W, and the extraction time was 30 min.
  • the extract product of Astragalus membranaceus was filtered to obtain a first filtrate, and the first filtrate was decolorized using activated carbon to obtain a first extract.
  • the mixture of peony root bark, Rhodiola and Artemisia annua L. was mixed to obtain a mixture, and 1633 parts by weight of ethanol having a concentration of 850 vt% was mixed and heated to 39 ° C, and the active ingredient of the mixture was extracted by ultrasonication to obtain an extract product of the mixture.
  • the extraction temperature was 39 ° C
  • the extraction power was 73 W
  • the extraction time was 32 min.
  • the extracted product of the mixture was filtered to obtain a second filtrate, and the second filtrate was decolorized using activated carbon to obtain a second extract.
  • the first extract and the second extract are mixed to obtain a sunscreen composition.
  • the components were prepared according to the following ratios: 5 wt% butanediol, 5.5 wt% glycerin, 0.5 wt% betaine, 1.0 wt% dipotassium glycyrrhizinate, 0.14 wt% sodium hyaluronate, 51 wt% Sunscreen composition, 3.5% by weight of aloe extract, 1.1% by weight of panthenol and the balance of water.
  • Butanediol, glycerin, betaine, dipotassium glycyrrhizinate and sodium hyaluronate are mixed to obtain a cosmetic base.
  • the cosmetic base was mixed with water at a temperature of 70 ° C, it was heated to a temperature of 95 ° C and maintained at this temperature for 40 minutes to obtain a base.
  • the sunscreen composition, the aloe extract, the panthenol and the base are mixed and cooled while cooling to a temperature of 45 ° C to obtain a sunscreen spray.
  • the dried medicinal material was prepared: 54 parts by weight of xanthine, 36 parts by weight of peony bark, 18 parts by weight of Rhodiola and 42 parts by weight of Artemisia annua. Astragalus, peony root bark, Rhodiola and Artemisia annua were pulverized to 45 mesh, and used.
  • the xanthine and 900 parts by weight of a 1.5 vt% acetic acid solution were mixed and heated to 47 ° C, and the active ingredient of the astragalus was extracted by ultrasonication to obtain an extract product of xanthine, specifically, the extraction temperature was 47 ° C, the extraction power was 59 W, and the extraction time was It is 30min.
  • the extract product of Astragalus membranaceus was filtered to obtain a first filtrate, and the first filtrate was decolorized using activated carbon to obtain a first extract.
  • the peony root bark, Rhodiola and Artemisia annua were mixed to obtain a mixture, and the mixture was mixed with 2376 parts by weight of 80 vt% ethanol and heated to 48 ° C, and the active ingredient of the mixture was extracted by ultrasonication to obtain an extract product of the mixture, specifically
  • the extraction temperature was 48 ° C
  • the extraction power was 63 W
  • the extraction time was 35 min.
  • the extracted product of the mixture was filtered to obtain a second filtrate, and the second filtrate was decolorized using activated carbon to obtain a second extract.
  • the first extract and the second extract are mixed to obtain a sunscreen composition.
  • the components were prepared according to the following ratios: 4.2 wt% of butanediol, 4.5 wt% of glycerol, 0.7 wt% of betaine, 0.6 wt% of dipotassium glycyrrhizinate, 0.17 wt% of sodium hyaluronate, 34 wt. % sunscreen composition, 5.0% by weight of aloe extract, 2.0% by weight of panthenol and the balance of water.
  • Butanediol, glycerin, betaine, dipotassium glycyrrhizinate and sodium hyaluronate are mixed to obtain a cosmetic base.
  • the cosmetic base was mixed with water at a temperature of 72 ° C, it was heated to a temperature of 95 ° C and maintained at this temperature for 31 minutes to obtain a base.
  • the sunscreen composition, the aloe extract, the panthenol and the base are mixed and cooled while cooling to a temperature of 45 ° C to obtain a sunscreen spray.
  • the sunscreen spray prepared in Example 1 was subjected to a spectrophotometric test.
  • the appropriate amount of the sunscreen spray prepared in Example 1 was taken as the sample to be tested.
  • the sample to be tested is applied to 5 quartz cuvettes having a thickness of 8 ⁇ m by a film method, namely, sample 1, sample 2, sample 3, sample 4, and sample 5, respectively, and samples 1 to 5 are measured. Average light transmittance in the wavelength range from 270 nm to 400 nm.
  • the sample to be tested is preferably applied in a volume of 1 mg/cm 2 in a quartz cuvette, and placed for 30 minutes after application, and then subjected to a spectrophotometric test. The measurement results are shown in Table 1.
  • the sunscreen spray sample prepared in Example 1 has an average absorbance of 1.988 in the wavelength range of 270 to 400 nm, and therefore, the sunscreen spray has a good sunscreen effect.
  • Butanediol, glycerin, betaine, dipotassium glycyrrhizinate and sodium hyaluronate are mixed to obtain a cosmetic base.
  • the cosmetic base was mixed with water at a temperature of 70 ° C, it was heated to a temperature of 95 ° C and maintained at this temperature for 36 minutes to obtain a base.
  • the sunscreen spray prepared in Comparative Example 1 was subjected to a spectrophotometric test.
  • the test operation was the same as that of the test operation of Example 1.
  • the sample of the comparative example was five, which were Comparative Sample 1, Comparative Sample 2, Comparative Sample 3, Comparative Sample 4, and Comparative Sample 5, and the measurement results are shown in Table 2. .
  • the sunscreen spray sample prepared in Comparative Example 1 had an average absorbance of 0.592 in the wavelength range of 270 to 400 nm. It can be understood that the sunscreen spray prepared in Example 1 under the same conditions has a good sunscreen effect in the wavelength range of 270 to 400 nm.
  • Example 1 The sunscreen spray prepared in Example 1 was separately subjected to a one-pack and a binary package 100. Five unpacked samples and five binary package samples of the same specification were prepared. Further, after using 1/3 of the five one-package samples and five binary package samples, all the samples were cultured at a constant temperature of 45 ° C for 15 days, and the samples were observed. The observation results are shown in Table 3.
  • the sunscreen spray with a binary package 100.
  • the first extract is obtained by extracting the astragalus, and the mixture of the peony root bark, Rhodiola and Artemisia annua L. is extracted to obtain a second extract, which will
  • the sunscreen composition can be prepared quickly by mixing the first extract and the second extract.
  • the sunscreen composition of the embodiment of the invention is a natural sunscreen composition with excellent properties, good sunscreen effect and good lightproof effect, high ultraviolet absorption intensity and strong absorption in the wavelength range of 270-400 nm. At the same time, it has the effect of eliminating free radicals generated by ultraviolet radiation of the skin.
  • the sunscreen spray of the embodiment of the invention uses the extracts of astragalus, peony root bark, Rhodiola and Artemisia annua as the sunscreen active ingredient, has the advantages of not blocking pores and not causing allergies, and is a safe sunscreen product. . It has the characteristics of low irritation, few side effects and safety and reliability, which can avoid the stimulation of human skin and the occurrence of allergies. Moreover, sunscreen sprays can effectively solve problems such as dermatitis, allergies or phototoxic reactions.
  • the preparation method of the sunscreen spray according to the embodiment of the present invention is prepared by using the above sunscreen composition as an active ingredient.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

一种防晒组合物、其制备方法、防晒喷雾剂及其制备方法。防晒组合物的制备方法，包括：对黄芩进行提取得到第一提取液，对牡丹根皮、红景天和青蒿的混合物进行提取得到第二提取液，将第一提取液和第二提取液混合。防晒喷雾剂，包括：3～5wt％的丁二醇、4～6wt％的甘油、0.2～1.2wt％的甜菜碱、0.3～1.3wt％的甘草酸二钾、0.05～0.2wt％的透明质酸钠、30～55wt％的上述的防晒组合物、3～5wt％的芦荟提取物、1～2.5wt％的泛醇和余量的水。防晒喷雾剂，以上述防晒组合物为原料制成，具有不堵塞毛孔和不造成过敏等优点，是一种安全性高的防晒产品。

Description

一种防晒组合物、其制备方法、防晒喷雾剂及其制备方法
相关申请的交叉引用
本申请要求于2017年08月08日提交中国专利局的申请号为CN201710673312.2、名称为“一种防晒组合物、其制备方法、防晒喷雾剂及其制备方法”的中国专利申请的优先权，其全部内容通过引用结合在本申请中。
技术领域
本发明涉及化妆品领域，且特别涉及一种防晒组合物、其制备方法、防晒喷雾剂及其制备方法。
背景技术
现有的化学防晒剂，存在紫外线吸收效果较差，使用时每隔一段时间需要重复涂抹。同时，化学防晒剂光照后会发生光学反应，容易导致皮炎或过敏等风险。
此外，现有的物理防晒剂中包含二氧化钛和/或氧化锌等物理防晒成分，这些细小的粒子能在皮肤表面形成阻挡层并通过反射、散射紫外线对皮肤起到保护作用的同时，具有较差的透明感，容易出现在皮肤表面沉积成白色层而脱落的现象，使用过多会造成毛孔的堵塞。
有鉴于此，提出本发明。
发明内容
本发明的第一目的在于提供一种防晒组合物，是一种性质优良的天然防晒组合物，具有防晒效果好和防光作用好的特点。
本发明的第二目的在于提供一种防晒喷雾剂，以上述防晒组合物为原料制成并且不添加物理防晒成分，具有不堵塞毛孔和不造成过敏等优点，是一种安全性高的防晒产品。
本发明解决其技术问题是采用以下技术方案来实现的。
本发明提出一种防晒组合物的制备方法，包括：
对黄芩进行提取得到第一提取液，对牡丹根皮、红景天和青蒿的混合物进行提取得到第二提取液，将第一提取液和第二提取液混合。
进一步地，在本发明较佳实施例中，上述黄芩、牡丹根皮、红景天和青蒿的质量比为1.5～3.5：1.5～2.5：1～2.3：2～4。
进一步地，在本发明较佳实施例中，上述将粉碎至45～60目的黄芩和0.9～2.9vt％的乙酸溶液按照质量比为1：15～25混合后，在38～49℃的温度下和40～60W的功率下萃取25～35min，对黄芩的萃取产物进行过滤得到第一滤液，使用活性炭对第一滤液脱色后得到第一提取液。
进一步地，在本发明较佳实施例中，上述将粉碎至45～60目的混合物和60～95vt％的乙醇按照质量比为1：15～25混合后，在38～49℃的温度下和60～80W的功率下萃取25～35min，对混合物的萃取产物进行过滤得到第二滤液，使用活性炭对第二滤液脱色后得到第二提取液。
本发明提出一种防晒组合物，根据上述的防晒组合物的制备方法制得。
本发明提出一种防晒喷雾剂，包括：
3～5wt％的丁二醇、4～6wt％的甘油、0.2～1.2wt的甜菜碱、0.3～1.3wt％的甘草酸二钾、0.05～0.2wt％的透明质酸钠、30～55wt％的上述的防晒组合物、3～5wt％的芦荟提取物、1～2.5wt％的泛醇和余量的水。
本发明提出一种防晒喷雾剂的制备方法，包括：
在40～50℃的温度下将上述的防晒组合物、芦荟提取物、泛醇和基料混合。
进一步地，在本发明较佳实施例中，将化妆品基质和温度为60～80℃的水混合并在95～100℃的温度下保持30～40min后得到基料。
进一步地，在本发明较佳实施例中，将丁二醇、甘油、甜菜碱、甘草酸二钾和透明质酸钠混合得到化妆品基质。
进一步地，在本发明较佳实施例中，还包括使用二元包装对防晒喷雾剂进行包装。
本发明实施例的有益效果是：
本发明实施例的防晒组合物的制备方法，通过对黄芩进行提取得到第一提取液，对牡丹根皮、红景天和青蒿的混合物进行提取得到第二提取液，将第一提取液和第二提取液混合即可快速的制备防晒组合物。
本发明实施例的防晒组合物，是一种性质优良的天然防晒组合物，防晒效果好和防光作用好，紫外线吸收强度大并在270～400nm的波长范围内皆有强吸收。同时，具有消除紫外辐射皮肤而产生的自由基的功效。
本发明实施例的防晒喷雾剂，以黄芩、牡丹根皮、红景天和青蒿的提取液作为防晒活性成分，具有不堵塞毛孔和不造成过敏等优点，是一种安全性高的防晒产品。具有刺激性低、副作用少和安全可靠等特点，能够避免对人体皮肤的刺激和过敏现象的产生。而且，防晒喷雾剂能有效解决皮炎、过敏或光毒反应等问题。
本发明实施例的防晒喷雾剂的制备方法，以上述的防晒组合物为活性成分制得。
附图说明
为了更清楚地说明本发明实施例的技术方案，下面将对实施例中所需要使用的附图作简单地介绍，应当理解，以下附图仅示出了本发明的某些实施例，因此不应被看作是对范围的限定，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这 些附图获得其他相关的附图。
图1为本发明提供的二元包装结构示意图；
图2为本发明提供的罐体结构示意图；
图3为本发明提供的气雾组件的结构示意图。
图标：100-二元包装；110-罐体；111-罐口；120-气囊；130-气雾组件；131-盖体；132-喷雾管；133-阀组件；140-喷头。
具体实施方式
为使本发明实施例的目的、技术方案和优点更加清楚，下面将对本发明实施例中的技术方案进行清楚、完整地描述。实施例中未注明具体条件者，按照常规条件或制造商建议的条件进行。所用试剂或仪器未注明生产厂商者，均为可以通过市售购买获得的常规产品。
下面对本发明实施例的防晒组合物、其制备方法、防晒喷雾剂及其制备方法进行具体说明。
一种防晒组合物的制备方法，包括：
按照黄芩、牡丹根皮、红景天和青蒿的质量比为1.5～3.5：1.5～2.5：1～2.3：2～4，分别备取黄芩、牡丹根皮、红景天和青蒿。
制备第一提取液。
将备取的黄芩和乙酸溶液按照质量比为1：15～25混合后进行萃取。具体地，在38～49℃的温度下和40～60W的功率下萃取25～35min，得到黄芩的萃取产物。对黄芩的萃取产物进行过滤得到第一滤液，使用活性炭对第一滤液脱色后得到第一提取液。
其中，乙酸溶液选用0.9～2.9vt％的乙酸溶液。
为了保证黄芩的萃取效果，黄芩在与乙酸溶液混合前，将黄芩粉碎至45～60目，得到黄芩粉末后再进行萃取操作。通过这样的操作，有效提高了物料的利用度。
制备第二提取液。
将备取的牡丹根皮、红景天和青蒿混合，得到混合物，即为牡丹根皮、红景天和青蒿混合的混合物。
将混合物和乙醇按照质量比为1：15～25混合后进行萃取。具体地，在38～49℃的温度下和60～80W的功率下萃取25～35min，得到混合物的萃取产物。对混合物的萃取产物进行过滤得到第二滤液，使用活性炭对第二滤液脱色后得到第二提取液。
其中，乙醇选用60～95vt％的乙醇。
为了保证牡丹根皮、红景天和青蒿的混合物的萃取效果，混合物在与乙酸溶液混合前，将混合物粉碎至45～60目，得到混合物末后再进行萃取操作。通过这样的操作，有效提高了物料的利用度。
将第一提取液和第二提取液混合，得到防晒组合物。即完成防晒组合物的制备。
黄芩、牡丹根皮、红景天和青蒿的提取液中包括苷类、多糖、黄酮类等物质，通过这个物质的协同作用形成上述的防晒组合物。
承上述，通过上述的防晒组合物的制备方法制得的防晒组合物，是一种性质优良的天然防晒组合物，防晒效果好和防光作用好，紫外线吸收强度大并在270～400nm的波长范围内皆有强吸收。同时，具有消除紫外辐射皮肤而产生的自由基的功效。
因此，该防晒组合物在皮肤修复、防晒和治疗中均具有广泛的用途。同时，本防晒组合物为天然防晒成分，具有刺激性低、副作用少和安全可靠等特点，能够避免对人体皮肤的刺激和过敏现象的产生。
一种防晒喷雾剂，组分中包括：丁二醇、甘油、甜菜碱、甘草酸二钾、透明质酸钠、上述防晒组合物、芦荟提取物、泛醇和水。
并且，上述组分按照以下配比混合：3～5wt％的丁二醇、4～6wt％的甘油、0.2～1.2wt％的甜菜碱、0.3～1.3wt％的甘草酸二钾、0.05～0.2wt％的透明质酸钠、30～55wt％的上述防晒组合物、3～5wt％的芦荟提取物、1～2.5wt％的泛醇和余量的水。
一种防晒喷雾剂的制备方法，包括：
按照防晒喷雾剂组分的上述原料配比，分别备取丁二醇、甘油、甜菜碱、甘草酸二钾、透明质酸钠、上述防晒组合物、芦荟提取物、泛醇和水。
将丁二醇、甘油、甜菜碱、甘草酸二钾和透明质酸钠混合得到化妆品基质。
将化妆品基质和温度为60～80℃水混合后，在95～100℃的温度下保持30～40min后得到基料。
作为优选，水的温度为75℃。
之后，在40～50℃的温度下防晒组合物、芦荟提取物、泛醇和基料混合，得到防晒喷雾剂。
承上述，防晒喷雾剂以黄芩、牡丹根皮、红景天和青蒿的提取液作为防晒活性成分，具有不堵塞毛孔和不造成过敏等优点，是一种安全性高的防晒产品。
采用二元包装100对防晒喷雾剂进行包装。请参照图1、图2和图3，二元包装100包括罐体110、气囊120、气雾组件130和喷头140。
其中，罐体110具有罐口111，罐体110内具有压缩空气。罐体110可以为铝罐或铁罐，也不限于本实施例的未列出的其它方式。
气雾组件130包括盖体131、喷雾管132和阀组件133。盖体131盖合于罐口111实现气雾组件130安装于罐体110。阀组件133设置于盖体131，喷雾管132与阀组件133连通并朝向远离罐体110的方向延伸。
气囊120用于盛放防晒喷雾剂。气囊120的开口端设置于阀组件133实现其开口端的封闭。请参照图3，气雾组件130未安装于罐体110时，气囊120呈圆柱状；请参照图1，气雾组件130安装于罐体110时，将罐体110内抽真空并通过喷雾管132向气囊120内通入防晒喷雾剂，气囊呈扩张状态。
喷头140罩设于喷雾管132，通过按压喷头140即可实现将气囊120内的防晒喷雾剂喷出。
此外，二元包装100还可以包括罩设于喷头140的盖体(图未绘示)，防止喷头140被外界污染。
通过二元包装100，能够防止防晒喷雾剂被二次污染，避免外界空气和喷雾内料接触导致修复防晒成分被氧化而失效，随着使用空气氧化时间延长喷雾料体会出现发黄和颜色变深现象。亦即，避免影响防晒喷雾剂的美观度。
同时，二元包装100无需添加推进剂，即可实现将防晒喷雾剂喷出于二元包装100。
以下结合实施例对本发明的特征和性能作进一步的详细描述。
实施例1
制备防晒组合物：
备取烘干的药材：25重量份的黄芩、20重量份的牡丹根皮、15重量份的红景天和40重量份的青蒿。将黄芩、牡丹根皮、红景天和青蒿分别粉碎至45目，备用。
将黄芩和500重量份的1.5vt％的乙酸溶液混合并加热到40℃，利用超声波法萃取黄芩的有效成分得到黄芩的萃取产物，具体地，萃取温度为40℃，萃取功率为55W，萃取时间为30min。对黄芩的萃取产物进行过滤得到第一滤液，使用活性炭对第一滤液脱色得到第一提取液。
将牡丹根皮、红景天和青蒿混合得到混合物，将混合物和1500重量份的浓度为90vt％的乙醇混合并加热到40℃，利用超声波法萃取混合物的有效成分得到混合物的萃取产物，具体地，萃取温度为40℃，萃取功率为70W，萃取时间为25min。对混合物的萃取产物进行过滤得到第二滤液，使用活性炭对第二滤液进行脱色得到第二提取液。
将第一提取液和第二提取液混合得到防晒组合物。
制备防晒喷雾剂：
按照以下配比备取各组分：4.2wt％的丁二醇、5.5wt％的甘油、0.3wt％的甜菜碱、0.3wt％的甘草酸二钾、0.07wt％的透明质酸钠、46wt％的防晒组合物、4.2wt％的芦荟提取物、1.1wt％的泛醇和余量的水。
将丁二醇、甘油、甜菜碱、甘草酸二钾和透明质酸钠混合得到化妆品基质。
将化妆品基质和温度为70℃水混合后，加热至95℃的温度并在该温度下保持36min后 得到基料。
之后，降温至45℃的温度下，将防晒组合物、芦荟提取物、泛醇和基料混合并搅拌均匀冷却后，得到防晒喷雾剂。
实施例2
制备防晒组合物：
备取烘干的药材：30重量份的黄芩、18重量份的牡丹根皮、20重量份的红景天和32重量份的青蒿。将黄芩、牡丹根皮、红景天和青蒿分别粉碎至50目，备用。
将黄芩和540重量份的1.5vt％的乙酸溶液混合并加热到42℃，利用超声波法萃取黄芩的有效成分得到黄芩的萃取产物，具体地，萃取温度为42℃，萃取功率为50W，萃取时间为28min。对黄芩的萃取产物进行过滤得到第一滤液，使用活性炭对第一滤液脱色得到第一提取液。
将牡丹根皮、红景天和青蒿混合得到混合物，将混合物和1400重量份的浓度为95vt％的乙醇混合并加热到43℃，利用超声波法萃取混合物的有效成分得到混合物的萃取产物，具体地，萃取温度为43℃，萃取功率为74W，萃取时间为28min。对混合物的萃取产物进行过滤得到第二滤液，使用活性炭对第二滤液进行脱色得到第二提取液。
将第一提取液和第二提取液混合得到防晒组合物。
制备防晒喷雾剂：
按照以下配比备取各组分：4.4wt％的丁二醇、5.1wt％的甘油、0.6wt％的甜菜碱、0.8wt％的甘草酸二钾、0.1wt％的透明质酸钠、50wt％的防晒组合物、4.6wt％的芦荟提取物、2.1wt％的泛醇和余量的水。
将丁二醇、甘油、甜菜碱、甘草酸二钾和透明质酸钠混合得到化妆品基质。
将化妆品基质和温度为75℃水混合后，加热至90℃的温度并在该温度下保持32min后得到基料。
之后，降温至45℃的温度下，将防晒组合物、芦荟提取物、泛醇和基料混合并搅拌均匀冷却后，得到防晒喷雾剂。
实施例3
制备防晒组合物：
备取烘干的药材：30重量份的黄芩、23重量份的牡丹根皮、23重量份的红景天和25重量份的青蒿。将黄芩、牡丹根皮、红景天和青蒿分别粉碎至60目，备用。
将黄芩和750重量份的1.5vt％的乙酸溶液混合并加热到47℃，利用超声波法萃取黄芩 的有效成分得到黄芩的萃取产物，具体地，萃取温度为47℃，萃取功率为50W，萃取时间为30min。对黄芩的萃取产物进行过滤得到第一滤液，使用活性炭对第一滤液脱色得到第一提取液。
将牡丹根皮、红景天和青蒿混合得到混合物，将混合物和1633重量份的浓度为850vt％的乙醇混合并加热到39℃，利用超声波法萃取混合物的有效成分得到混合物的萃取产物，具体地，萃取温度为39℃，萃取功率为73W，萃取时间为32min。对混合物的萃取产物进行过滤得到第二滤液，使用活性炭对第二滤液进行脱色得到第二提取液。
将第一提取液和第二提取液混合得到防晒组合物。
制备防晒喷雾剂：
按照以下配比备取各组分：5wt％的丁二醇、5.5wt％的甘油、0.5wt％的甜菜碱、1.0wt％的甘草酸二钾、0.14wt％的透明质酸钠、51wt％的防晒组合物、3.5wt％的芦荟提取物、1.1wt％的泛醇和余量的水。
将丁二醇、甘油、甜菜碱、甘草酸二钾和透明质酸钠混合得到化妆品基质。
将化妆品基质和温度为70℃水混合后，加热至95℃的温度并在该温度下保持40min后得到基料。
之后，降温至45℃的温度下，将防晒组合物、芦荟提取物、泛醇和基料混合并搅拌均匀冷却后，得到防晒喷雾剂。
实施例4
制备防晒组合物：
备取烘干的药材：54重量份的黄芩、36重量份的牡丹根皮、18重量份的红景天和42重量份的青蒿。将黄芩、牡丹根皮、红景天和青蒿分别粉碎至45目，备用。
将黄芩和900重量份的1.5vt％的乙酸溶液混合并加热到47℃，利用超声波法萃取黄芩的有效成分得到黄芩的萃取产物，具体地，萃取温度为47℃，萃取功率为59W，萃取时间为30min。对黄芩的萃取产物进行过滤得到第一滤液，使用活性炭对第一滤液脱色得到第一提取液。
将牡丹根皮、红景天和青蒿混合得到混合物，将混合物和2376重量份的浓度为80vt％的乙醇混合并加热到48℃，利用超声波法萃取混合物的有效成分得到混合物的萃取产物，具体地，萃取温度为48℃，萃取功率为63W，萃取时间为35min。对混合物的萃取产物进行过滤得到第二滤液，使用活性炭对第二滤液进行脱色得到第二提取液。
将第一提取液和第二提取液混合得到防晒组合物。
制备防晒喷雾剂：
按照以下配比备取各组分：4.2wt％的丁二醇、4.5wt％的甘油、0.7wt％的甜菜碱、0.6wt％的甘草酸二钾、0.17wt％的透明质酸钠、34wt％的防晒组合物、5.0wt％的芦荟提取物、2.0wt％的泛醇和余量的水。
将丁二醇、甘油、甜菜碱、甘草酸二钾和透明质酸钠混合得到化妆品基质。
将化妆品基质和温度为72℃水混合后，加热至95℃的温度并在该温度下保持31min后得到基料。
之后，降温至45℃的温度下，将防晒组合物、芦荟提取物、泛醇和基料混合并搅拌均匀冷却后，得到防晒喷雾剂。
对实施例1制备的防晒喷雾剂进行分光光度测试。
取实施例1制备的防晒喷雾剂适量，作为待测样。使用薄膜法将待测样涂抹于8μm厚的5个石英比色皿上，分别即为试样1、试样2、试样3、试样4和试样5，测定试样1～5在270nm～400nm波长区间平均透光率。其中，待测样在石英比色皿按1mg/cm2的量涂抹为宜，涂抹后放置30min，再进行分光光度测试。测量结果见表1。
表1 实施例1试样的分光光度的测量结果
Figure PCTCN2017109784-appb-000001
从表1可以看出，实施例1制得的防晒喷雾剂样品喷雾在270～400nm波长范围内平均吸光度为1.898，因此，该防晒喷雾剂具有良好防晒效果。
对比例1
制备防晒喷雾剂：
4.2wt％的丁二醇、5.5wt％的甘油、0.3wt％的甜菜碱、0.3wt％的甘草酸二钾、0.07wt％的透明质酸钠、46wt％的防晒组合物、4.2wt％的芦荟提取物、1.1wt％的泛醇和余量的水。
将丁二醇、甘油、甜菜碱、甘草酸二钾和透明质酸钠混合得到化妆品基质。
将化妆品基质和温度为70℃水混合后，加热至95℃的温度并在该温度下保持36min后得到基料。
之后，降温至45℃的温度下，将芦荟提取物、泛醇和基料混合并搅拌均匀冷却后，得到对比例的防晒喷雾剂。
对对比例1制备的防晒喷雾剂进行分光光度测试。测试操作同实施例1的测试操作，同样地，对比例的样品即为5个，分别即为对比样1、对比样2、对比样3、对比样4和对比样5，测量结果见表2。
表2 对比例1试样的分光光度的测量结果
波长/nm 对比样1 对比样2 对比样3 对比样4 对比样5
270 1.123 1.138 1.197 1.102 1.158
290 0.872 0.852 0.842 0.873 0.851
310 0.642 0.602 0.641 0.652 0.663
330 0.542 0.502 0.541 0.552 0.563
350 0.423 0.442 0.401 0.413 0.401
370 0.375 0.475 0.398 0.412 0.391
390 0.356 0.361 0.372 0.382 0.382
400 0.343 0.372 0.365 0.361 0.352
均值 0.585 0.593 0.595 0.593 0.595
从表2可以看出，对比例1制得的防晒喷雾剂样品喷雾在270～400nm波长范围内平均吸光度为0.592。可以理解，相同条件的实施例1制备的防晒喷雾剂，在270～400nm波长范围内具备较好的防晒效果。
对比例2
取实施例1制备的防晒喷雾剂，分别进行一元包装和二元包装100。制备同规格5个一元包装试样和5个二元包装试样。并且，将5个一元包装试样和5个二元包装试样全部使用1/3后，将全部样品在45℃的温度下恒温培养15天，对样品进行观测。观测结果见表3。
表3 观测结果
Figure PCTCN2017109784-appb-000002
Figure PCTCN2017109784-appb-000003
从表3中可以看出，二元包装100的试样颜色变化情况明显优于一元包装的试样，说明二元包装100能够有效解决防晒喷雾剂在使用过程中被污染以及被氧化等问题，二元包装100保证产品具有更加稳定的功效。
因此，优选选用二元包装100对防晒喷雾剂进行包装。
综上所述，本发明实施例的防晒组合物的制备方法，通过对黄芩进行提取得到第一提取液，对牡丹根皮、红景天和青蒿的混合物进行提取得到第二提取液，将第一提取液和第二提取液混合即可快速的制备防晒组合物。
本发明实施例的防晒组合物，是一种性质优良的天然防晒组合物，防晒效果好和防光作用好，紫外线吸收强度大并在270～400nm的波长范围内皆有强吸收。同时，具有消除紫外辐射皮肤而产生的自由基的功效。
本发明实施例的防晒喷雾剂，以黄芩、牡丹根皮、红景天和青蒿的提取液作为防晒活性成分，具有不堵塞毛孔和不造成过敏等优点，是一种安全性高的防晒产品。具有刺激性低、副作用少和安全可靠等特点，能够避免对人体皮肤的刺激和过敏现象的产生。而且，防晒喷雾剂能有效解决皮炎、过敏或光毒反应等问题。
本发明实施例的防晒喷雾剂的制备方法，以上述的防晒组合物为活性成分制得。
以上所描述的实施例是本发明一部分实施例，而不是全部的实施例。本发明的实施例的详细描述并非旨在限制要求保护的本发明的范围，而是仅仅表示本发明的选定实施例。基于本发明中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。

Claims (10)

  1. 一种防晒组合物的制备方法，其特征在于，包括：
    对黄芩进行提取得到第一提取液，对牡丹根皮、红景天和青蒿的混合物进行提取得到第二提取液，将所述第一提取液和所述第二提取液混合。
  2. 根据权利要求1所述的防晒组合物的制备方法，其特征在于，所述黄芩、所述牡丹根皮、所述红景天和所述青蒿的质量比为1.5～3.5：1.5～2.5：1～2.3：2～4。
  3. 根据权利要求1或2所述的防晒组合物的制备方法，其特征在于，将粉碎至45～60目的所述黄芩和0.9～2.9vt％的乙酸溶液按照质量比为1：15～25混合后，在38～49℃的温度下和40～60W的功率下萃取25～35min，对所述黄芩的萃取产物进行过滤得到第一滤液，使用活性炭对所述第一滤液脱色后得到所述第一提取液。
  4. 根据权利要求1或2所述的防晒组合物的制备方法，其特征在于，将粉碎至45～60目的所述混合物和60～95vt％的乙醇按照质量比为1：15～25混合后，在38～49℃的温度下和60～80W的功率下萃取25～35min，对所述混合物的萃取产物进行过滤得到第二滤液，使用活性炭对所述第二滤液脱色后得到所述第二提取液。
  5. 一种防晒组合物，其特征在于，根据权利要求1～4任一项所述的防晒组合物的制备方法制得。
  6. 一种防晒喷雾剂，其特征在于，包括：
    3～5wt％的丁二醇、4～6wt％的甘油、0.2～1.2wt％的甜菜碱、0.3～1.3wt％的甘草酸二钾、0.05～0.2wt％的透明质酸钠、30～55wt％的如权利要求5所述的防晒组合物、3～5wt％的芦荟提取物、1～2.5wt％的泛醇和余量的水。
  7. 一种防晒喷雾剂的制备方法，其特征在于，包括：
    在40～50℃的温度下将如权利要求5所述的防晒组合物、芦荟提取物、泛醇和基料混合。
  8. 根据权利要求7所述的防晒喷雾剂的制备方法，其特征在于，将化妆品基质和温度为60～80℃的水混合并在95～100℃的温度下保持30～40min后得到基料。
  9. 根据权利要求8所述的防晒喷雾剂的制备方法，其特征在于，将丁二醇、甘油、甜菜碱、甘草酸二钾和透明质酸钠混合得到所述化妆品基质。
  10. 根据权利要求7所述的防晒喷雾剂的制备方法，其特征在于，还包括使用二元包装对所述防晒喷雾剂进行包装。
PCT/CN2017/109784 2017-08-08 2017-11-07 一种防晒组合物、其制备方法、防晒喷雾剂及其制备方法 WO2019029029A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201710673312.2A CN107412060B (zh) 2017-08-08 2017-08-08 一种防晒喷雾剂及其制备方法
CN201710673312.2 2017-08-08

Publications (1)

Publication Number Publication Date
WO2019029029A1 true WO2019029029A1 (zh) 2019-02-14

Family

ID=60437735

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2017/109784 WO2019029029A1 (zh) 2017-08-08 2017-11-07 一种防晒组合物、其制备方法、防晒喷雾剂及其制备方法

Country Status (2)

Country Link
CN (1) CN107412060B (zh)
WO (1) WO2019029029A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108478508A (zh) * 2018-05-29 2018-09-04 佛山市顺德区香江精细化工实业有限公司 一种晒后修复喷雾剂及其制备方法
CN109394972A (zh) * 2018-12-19 2019-03-01 辽宁石油化工大学 一种中药防晒配方及其制备方法和应用
CN114010513A (zh) * 2021-11-12 2022-02-08 杨伟业 一种止痒护肤喷雾及其制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406577A (zh) * 2011-11-28 2012-04-11 广东轻工职业技术学院 一种具有防晒功能的中药组合物及其提取物的制备方法和应用
CN103893064A (zh) * 2014-03-22 2014-07-02 南通蛇类治疗研究所 营养元素中药酵素酶防晒霜
CN104918603A (zh) * 2012-12-27 2015-09-16 株式会社林原 抗老化用的皮肤外用组合物及其制造方法
CN106236644A (zh) * 2016-08-26 2016-12-21 广州市美集化妆品科技有限公司 一种水嫩润透精华液
CN106821867A (zh) * 2017-04-03 2017-06-13 南通蛇类治疗研究所 天然植物酵素酶防晒霜

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2330606Y (zh) * 1997-01-22 1999-07-28 李�浩 二元包装罐
CN101361702B (zh) * 2008-09-11 2010-09-08 赖福平 纳米防晒粉底霜及其制备方法
CN201538516U (zh) * 2009-07-01 2010-08-04 李新建 二元包装罐
CN106420381A (zh) * 2016-08-08 2017-02-22 辛成业 青蒿素类成分或其组合物在皮肤护理中的新应用

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102406577A (zh) * 2011-11-28 2012-04-11 广东轻工职业技术学院 一种具有防晒功能的中药组合物及其提取物的制备方法和应用
CN104918603A (zh) * 2012-12-27 2015-09-16 株式会社林原 抗老化用的皮肤外用组合物及其制造方法
CN103893064A (zh) * 2014-03-22 2014-07-02 南通蛇类治疗研究所 营养元素中药酵素酶防晒霜
CN106236644A (zh) * 2016-08-26 2016-12-21 广州市美集化妆品科技有限公司 一种水嫩润透精华液
CN106821867A (zh) * 2017-04-03 2017-06-13 南通蛇类治疗研究所 天然植物酵素酶防晒霜

Also Published As

Publication number Publication date
CN107412060B (zh) 2020-07-24
CN107412060A (zh) 2017-12-01

Similar Documents

Publication Publication Date Title
ES2890440T3 (es) Polvos recubiertos que tienen alta fotostabilidad
WO2019029029A1 (zh) 一种防晒组合物、其制备方法、防晒喷雾剂及其制备方法
KR100717490B1 (ko) 티탄실리카 복합체 및 그것을 배합한 화장료
CN106176377B (zh) 一种植物来源的防晒增效组合物及其制备方法
KR20160144779A (ko) 무기계 자외선 차단제의 수분산액 제조방법 및 이를 포함하는 화장료 조성물
Shekhawat et al. Biogenesis of zinc oxide nanoparticles using Morinda pubescens JE Smith extracts and their characterization
CN103800269A (zh) 一种纳米氧化锌防晒霜
KR101737763B1 (ko) 열린 다공성 유무기 복합분체와 그의 제조방법 및 이를 포함하는 화장료 조성물
EP2664317B1 (en) Glass flake and cosmetics comprising same
BR112018014719B1 (pt) Composições aquosas e cápsulas duras de duas peças resultantes compreendendo concentrados alimentícios corantes hidrofílicos, processo de moldagem de imersão para fabricação de cápsulas duras de duas peças e uso de um ou mais corantes
Argade et al. Albizzia lebbeck extract mediated synthesis of Zinc Oxide Nanoparticles and study of its In-vitro Anti-diabetic and Anti-oxidant activity
WO2019223810A1 (zh) 一种包含α-倒捻子素的化妆品组合物、其制备方法及其用途
CN106700763A (zh) 一种明目内墙水漆及其制备方法
Kumar et al. Determination of sun protection factor in different extract of Eulaliopsis Binata
CN108815007A (zh) 一种基于玉米蛋白的纳米防晒剂及其制备方法和应用
KR20150145947A (ko) 캣츠클로, 아이슬란드 이끼 및 아사이베리 혼합 추출물을 유효성분으로 하는 자외선 차단용 화장료 조성물
KR102158010B1 (ko) 자외선 차단용 티타늄디옥사이드-멜라노이딘 복합체, 이의 제조방법 및 이를 포함하는 자외선 차단용 화장료 조성물
TWI496586B (zh) 改質複合微粒、其製造方法及其防曬配方
CN107714548A (zh) 一种植物防晒霜及其制备方法
Muruganantham et al. Design and evaluation of isolated herbal extracts of aloin, proanthocyanidin, quercetin loaded microsponge as sunscreen gel
KR101238379B1 (ko) 자외선흡수제가 포집된 이산화티타늄 캡슐 및 이를 함유하는 화장료 조성물
KR101662056B1 (ko) 자외선 차단성 유화제
TW202108129A (zh) 四物湯複合奈米顆粒及其製作方法
KR102654855B1 (ko) 복합 분체를 포함하는 화장료 조성물
JP7402567B2 (ja) 紫外線及び細塵遮断機能を有するアンチポリューション複合粉体及びこれを含む化粧料組成物

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 17921212

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 17921212

Country of ref document: EP

Kind code of ref document: A1