WO2019017612A3 - 기능성 나노투과막이 수직적으로 고정된 마이크로칩 및 이의 제조방법 - Google Patents

기능성 나노투과막이 수직적으로 고정된 마이크로칩 및 이의 제조방법 Download PDF

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WO2019017612A3
WO2019017612A3 PCT/KR2018/007456 KR2018007456W WO2019017612A3 WO 2019017612 A3 WO2019017612 A3 WO 2019017612A3 KR 2018007456 W KR2018007456 W KR 2018007456W WO 2019017612 A3 WO2019017612 A3 WO 2019017612A3
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permeable membrane
microchip
manufacturing
method therefor
vertically fixed
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PCT/KR2018/007456
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English (en)
French (fr)
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WO2019017612A9 (ko
WO2019017612A2 (ko
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이광호
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강원대학교산학협력단
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Publication of WO2019017612A3 publication Critical patent/WO2019017612A3/ko
Publication of WO2019017612A9 publication Critical patent/WO2019017612A9/ko

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0652—Sorting or classification of particles or molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/088—Channel loops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0896—Nanoscaled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Micromachines (AREA)

Abstract

본 발명은 기능성 나노투과막이 수직적이며 영구적으로 고정된 PDMS 또는 PMMA 기반의 마이크로칩 및 이의 제조방법에 관한 것으로, 본 발명에 따르면, 나노투과막이 수직적으로 고정된 PDMS 또는 PMMA기반의 마이크로칩은 나노투과막에 의해 공간적으로 분리된 시료사이에서 발생하는 선택적 물질이동에 의한 물리적 및 화학적 반응을 원리를 사용하는 미세유체 반응 시스템(microfluidic reaction system)에 적용될 수 있다.
PCT/KR2018/007456 2017-07-21 2018-07-02 기능성 나노투과막이 수직적으로 고정된 마이크로칩 및 이의 제조방법 WO2019017612A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2017-0092443 2017-07-21
KR1020170092443A KR102043027B1 (ko) 2017-07-21 2017-07-21 기능성 나노투과막이 수직적으로 고정된 마이크로칩 및 이의 제조방법

Publications (3)

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WO2019017612A2 WO2019017612A2 (ko) 2019-01-24
WO2019017612A3 true WO2019017612A3 (ko) 2019-03-28
WO2019017612A9 WO2019017612A9 (ko) 2019-05-16

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WO (1) WO2019017612A2 (ko)

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Publication number Priority date Publication date Assignee Title
CN112857956B (zh) * 2021-01-29 2022-08-02 天津工业大学 一种毛细管压力差强化浓缩的渗透芯片

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4313682B2 (ja) * 2004-01-16 2009-08-12 アイダエンジニアリング株式会社 Ｐｄｍｓ基板と他の合成樹脂基板との接着方法及びマイクロチップの製造方法
KR101229961B1 (ko) * 2011-03-18 2013-02-05 국립대학법인 울산과학기술대학교 산학협력단 미세 유체 유동 시스템
KR101565835B1 (ko) * 2013-11-07 2015-11-06 한국과학기술원 복제 몰드 제조 방법 및 이를 이용한 미세 구조 및 그 활용.
KR20160134285A (ko) * 2015-05-15 2016-11-23 포항공과대학교 산학협력단 나노파이버 멤브레인이 결합된 미세유체장치 및 이의 제작방법
KR101718951B1 (ko) * 2016-06-30 2017-03-22 광운대학교 산학협력단 생체 분자 농축 장치 및 그 제조방법

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110081677A1 (en) * 2009-09-30 2011-04-07 University Of Maryland, College Park Active Microfluidic Membranes
KR101446687B1 (ko) 2014-02-10 2014-10-06 동아대학교 산학협력단 나노섬유기반 세포배양 나노구조체 및 이를 포함하는 에세이 칩

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4313682B2 (ja) * 2004-01-16 2009-08-12 アイダエンジニアリング株式会社 Ｐｄｍｓ基板と他の合成樹脂基板との接着方法及びマイクロチップの製造方法
KR101229961B1 (ko) * 2011-03-18 2013-02-05 국립대학법인 울산과학기술대학교 산학협력단 미세 유체 유동 시스템
KR101565835B1 (ko) * 2013-11-07 2015-11-06 한국과학기술원 복제 몰드 제조 방법 및 이를 이용한 미세 구조 및 그 활용.
KR20160134285A (ko) * 2015-05-15 2016-11-23 포항공과대학교 산학협력단 나노파이버 멤브레인이 결합된 미세유체장치 및 이의 제작방법
KR101718951B1 (ko) * 2016-06-30 2017-03-22 광운대학교 산학협력단 생체 분자 농축 장치 및 그 제조방법

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KR102043027B1 (ko) 2019-11-27
WO2019017612A9 (ko) 2019-05-16
KR20190010118A (ko) 2019-01-30
WO2019017612A2 (ko) 2019-01-24

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