WO2018216893A3 - 바이오 칩용 필라 구조체 - Google Patents

바이오 칩용 필라 구조체 Download PDF

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Publication number
WO2018216893A3
WO2018216893A3 PCT/KR2018/003766 KR2018003766W WO2018216893A3 WO 2018216893 A3 WO2018216893 A3 WO 2018216893A3 KR 2018003766 W KR2018003766 W KR 2018003766W WO 2018216893 A3 WO2018216893 A3 WO 2018216893A3
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WO
WIPO (PCT)
Prior art keywords
biochip
pillar structure
substrate
pillar
plate
Prior art date
Application number
PCT/KR2018/003766
Other languages
English (en)
French (fr)
Other versions
WO2018216893A2 (ko
Inventor
구보성
이돈정
Original Assignee
엠비디 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 엠비디 주식회사 filed Critical 엠비디 주식회사
Priority to EP20211447.6A priority Critical patent/EP3804856A1/en
Priority to EP18732231.8A priority patent/EP3632562B8/en
Priority to US16/073,624 priority patent/US10967369B2/en
Publication of WO2018216893A2 publication Critical patent/WO2018216893A2/ko
Publication of WO2018216893A3 publication Critical patent/WO2018216893A3/ko

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B01L9/523—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips for multisample carriers, e.g. used for microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251—Colorimeters; Construction thereof
    • G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B01J2219/00317—Microwell devices, i.e. having large numbers of wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00504—Pins
    • B01J2219/00509—Microcolumns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/16—Surface properties and coatings
    • B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
    • B01L2300/163—Biocompatibility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/0303—Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • G01N2021/0307—Insert part in cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/08—Optical fibres; light guides
    • G01N2201/0806—Light rod

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

본 발명은 바이오 칩용 필라 구조체에 관한 것으로,판상 구조로 이루어진 기판; 및 일측은 상기 기판에 착탈 가능하게 결합되고, 타측은 상기 시료가 배치되는 필라부재들;을 포함하여 이루어지는 것을 특징으로 한다.
PCT/KR2018/003766 2017-05-24 2018-03-30 바이오 칩용 필라 구조체 WO2018216893A2 (ko)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP20211447.6A EP3804856A1 (en) 2017-05-24 2018-03-30 Pillar structure for biochip
EP18732231.8A EP3632562B8 (en) 2017-05-24 2018-03-30 Pillar structure for biochip
US16/073,624 US10967369B2 (en) 2017-05-24 2018-03-30 Pillar structure for biochip

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170063965A KR101952503B1 (ko) 2017-05-24 2017-05-24 바이오 칩용 필라 구조체
KR10-2017-0063965 2017-05-24

Publications (2)

Publication Number Publication Date
WO2018216893A2 WO2018216893A2 (ko) 2018-11-29
WO2018216893A3 true WO2018216893A3 (ko) 2019-01-17

Family

ID=64395686

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2018/003766 WO2018216893A2 (ko) 2017-05-24 2018-03-30 바이오 칩용 필라 구조체

Country Status (4)

Country Link
US (1) US10967369B2 (ko)
EP (2) EP3804856A1 (ko)
KR (1) KR101952503B1 (ko)
WO (1) WO2018216893A2 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD816861S1 (en) * 2016-09-07 2018-05-01 EMULATE, Inc. Transparent microfluidic chip without pressure features for use with a fluid perfusion module
USD842493S1 (en) * 2016-09-07 2019-03-05 EMULATE, Inc. Microfluidic chip without pressure features for use with a fluid perfusion module
KR101997389B1 (ko) * 2018-01-30 2019-07-08 엠비디 주식회사 바이오 칩용 필라 유닛
KR102193016B1 (ko) * 2018-12-17 2020-12-18 엠비디 주식회사 바이오 칩용 필라 구조체
KR102565767B1 (ko) * 2023-01-27 2023-08-10 엠비디 주식회사 3차원 공배양 플랫폼 및 이를 이용한 공배양방법

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR200330168Y1 (ko) * 2003-07-04 2003-10-17 (주)티에스이 볼 그리드 어레이(ｂｇａ) 패키지용 테스트 소켓
US20060103051A1 (en) * 2004-11-12 2006-05-18 Staats Sau Lan T Microfluidic array devices and methods of manufacture thereof
KR101184524B1 (ko) * 2010-12-22 2012-09-19 삼성전기주식회사 세포칩
KR101422941B1 (ko) * 2012-12-06 2014-07-23 삼성전기주식회사 바이오 칩
KR101632425B1 (ko) * 2015-12-11 2016-06-21 이돈정 바이오 칩 구조체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3927570B2 (ja) 1995-07-31 2007-06-13 プレシジョン・システム・サイエンス株式会社 容器
JPH11276154A (ja) * 1998-03-30 1999-10-12 Takahisa Matsue 試料の同時転写装置
DE10204531A1 (de) * 2002-02-01 2003-08-21 Inst Chemo Biosensorik Deckelelement
ES2704039T3 (es) * 2005-06-10 2019-03-13 Nunc As Soporte de elemento de inserción de cultivo, elemento de inserción de cultivo y sistema de elemento de inserción de cultivo
WO2007035604A2 (en) * 2005-09-16 2007-03-29 Becton, Dickinson And Company Scaffold carrier cartridge
KR101167435B1 (ko) * 2010-10-28 2012-07-19 삼성전기주식회사 세포칩

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR200330168Y1 (ko) * 2003-07-04 2003-10-17 (주)티에스이 볼 그리드 어레이(ｂｇａ) 패키지용 테스트 소켓
US20060103051A1 (en) * 2004-11-12 2006-05-18 Staats Sau Lan T Microfluidic array devices and methods of manufacture thereof
KR101184524B1 (ko) * 2010-12-22 2012-09-19 삼성전기주식회사 세포칩
KR101422941B1 (ko) * 2012-12-06 2014-07-23 삼성전기주식회사 바이오 칩
KR101632425B1 (ko) * 2015-12-11 2016-06-21 이돈정 바이오 칩 구조체

Also Published As

Publication number Publication date
KR101952503B1 (ko) 2019-03-04
EP3632562A4 (en) 2020-06-03
EP3632562B8 (en) 2022-04-06
EP3632562A2 (en) 2020-04-08
EP3804856A1 (en) 2021-04-14
WO2018216893A2 (ko) 2018-11-29
US20190134625A1 (en) 2019-05-09
EP3632562B1 (en) 2021-06-02
US10967369B2 (en) 2021-04-06
KR20180128622A (ko) 2018-12-04

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