WO2018206172A1 - Compositions pour soins buccaux - Google Patents

Compositions pour soins buccaux Download PDF

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Publication number
WO2018206172A1
WO2018206172A1 PCT/EP2018/054573 EP2018054573W WO2018206172A1 WO 2018206172 A1 WO2018206172 A1 WO 2018206172A1 EP 2018054573 W EP2018054573 W EP 2018054573W WO 2018206172 A1 WO2018206172 A1 WO 2018206172A1
Authority
WO
WIPO (PCT)
Prior art keywords
oral care
care composition
composition according
pigment
amphoteric surfactant
Prior art date
Application number
PCT/EP2018/054573
Other languages
English (en)
Inventor
Andrew Joiner
David Thomas Littlewood
Carole Jane Philpotts
Original Assignee
Unilever Plc
Unilever N.V.
Conopco, Inc., D/B/A Unilever
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Plc, Unilever N.V., Conopco, Inc., D/B/A Unilever filed Critical Unilever Plc
Publication of WO2018206172A1 publication Critical patent/WO2018206172A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42—Colour properties
    • A61K2800/43—Pigments; Dyes

Definitions

  • the present invention relates to oral care compositions that enhance the white appearance of teeth.
  • compositions comprising pigments that whiten the teeth are disclosed in W016099544 and WO 150975709.
  • EP 1 935 395 discloses whitening composition comprising a pigment having a hue angle, h, in the CIELAB system of from 220 to 320 degrees and a soluble deposition aid for the pigment.
  • the object of the invention is to deliver an improved whitening benefit to the teeth.
  • the present invention relates to an oral care composition
  • an oral care composition comprising an amphoteric surfactant and a pigment having a hue angle, h, in the CIELAB system of from 220 to 320 degrees.
  • the invention relates to Use of the composition according to any of the previous claims for enhanced whitening of the teeth.
  • compositions according to the invention comprise a pigment having a hue angle, h, in the CIELAB system of from 220 to 320 degrees most preferably between 250 and 290 degrees.
  • hue angle may be found on p57 of Colour Chemistry 3rd edition by H. Zollinger published by Wiley-VCH.
  • a pigment is generally understood to be a shade/material which is insoluble in the relevant medium, at the relevant temperature. This is in contrast to dyes which are soluble.
  • the "relevant medium” is human saliva, the liquid medium in which the composition is used, at the temperature of the oral cavity during brushing of the teeth, i.e. up to 37°C. As a reasonable approximation, the relevant medium may be considered to be water and the relevant temperature to be 25°C.
  • the pigment is capable of reflecting sufficient light such that the treated tooth is perceivably whiter than its initial colour.
  • the pigment is coloured such that its natural colour is within the violet-red to green-blue colour, preferably from violet to blue.
  • the pigment is violet or blue, more preferably one of those listed in the Colour Index International. These pigments are listed as pigment violet 1 through to pigment violet 56 and pigment blue 1 through 83.
  • the preferred pigment violets are pigment violet 1 , 1 :1 , 1 :2, 2, 3, 5:1 , 13, 19, 23, 25, 27, 31 , 32, 37, 39, 42, 44 and 50.
  • the preferred pigment blues are pigment blue 1 , 2, 9, 10, 14, 15, 15:1 , 15:2, 15:3, 15:4, 15:6 16, 18, 19, 24:1 , 25, 56, 60, 61 , 62 and 66.
  • pigment ultramarine blue and ultramarine violet are examples of suitable pigments.
  • the pigment is Pigment Blue 15, more preferably Pigment Blue 15:1 , 15:2, 15:3, 15:4, 15:5 or 15:6, most preferably 15:1.
  • Blue covarine is especially preferred.
  • the amount of pigment in the composition is preferably from 0.001 to 0.3%, more preferably from 0.005 to 0.1 %, and most preferably from 0.021to 0.08% by weight.
  • the percentage weights refer to the total amount of active present and exclude any carriers that may be present.
  • the pigment may be uniformly spread throughout the composition or, it may be dispersed in a second phase such as a stripe or other co-extruded second phase.
  • Compositions of the invention comprise a water soluble, polymeric deposition aid.
  • a "water soluble" polymeric deposition aid is a material that is soluble in water, typically having a solubility of 0.5% or greater, and more typically 5% or greater by weight, at 25°C.
  • a material remains soluble following drying - i.e. it can be re-dissolved following drying.
  • Such materials are polymers, but are not film- forming polymers. Water solubility is required in order to avoid buildup of the deposition aid on the teeth, something that can also be a particular problem with film-forming polymers.
  • the soluble polymeric deposition aid enhances deposition of the pigment onto the teeth and thereby enhances the colour change caused by the pigment.
  • a deposition agent in accordance with the invention is able to enhance the deposition of a pigment such as Blue Covarine when incorporated in a composition at a level of 0.02% by weight, particularly when the deposition aid is itself incorporated at a level of 1 % by weight.
  • the deposition aid is incorporated into the composition at preferably from 0.01 to 10%, more preferably at from 0.05 to 5%, and most preferably at from 0.1 to 1 % by weight.
  • Deposition aids for use in accordance with the present invention are typically high molecular weight polymers, i.e. polymers having a molecular weight of 200,000 or greater.
  • Preferred deposition aids are Gantrez® type polymers and high molecular weight PEGs.
  • Particularly preferred deposition aids are Gantrez® type polymers and high molecular weight PEGs.
  • Especially preferred deposition aids are Gantrez® type polymers.
  • Gantrez® type polymers are co-polymers of maleic anhydride with methyl vinylether, in which the anhydride moiety may be in a partially or fully hydrolysed or alcoholysed form.
  • Gantrez® polymers themselves are available from ISP Inc. Suitable Gantrez® polymers are: Gantrez S-95: molecular weight 216,000; free acid; Gantrez S-96: molecular weight 700,000; free acid; Gantrez S-97: molecular weight 1 ,500,000; free acid; and
  • Gantrez MS-955 molecular weight 1 ,060,000; calcium/sodium salt.
  • Gantrez® type polymers in which the anhydride moiety is fully hydrolysed are preferred. These may be thought of as co-polymers of maleic acid and methyl vinylether. Particularly preferred co-polymers of maleic acid and methyl vinylether have a molecular weight of 1 ,000,000 or greater and an especially preferred material is Gantrez S-97.
  • High molecular weight PEGs are poly(ethyleneglycol) polymers having a molecular weight of 1 ,000,000 or greater, preferably 2,000,000 or greater.
  • a preferred high molecular weight PEG is Polyox 60K, a polymer having a molecular weight of
  • the oral care composition comprises an amphoteric surfactants.
  • Amphoteric surfactants are surfactants of which the hydrophilic group has both acid and alkaline properties, depending upon the pH of the medium in which they are present. In acid media they form cations, and in alkaline media anions. In the isoelectric pH range they are present in the form of zwitterions.
  • Typical examples of amphoteric surfactants can be represented by the following general formula:
  • amphoteric surfactants are the alkylglycinates, alkylproprionates, betaines, sulphobetaines, phosphatobetaines, as well as tertiary amine oxides which, although not amphoteric in structure, behave like amphoteric surfactants.
  • Betaines are preferred as amphoteric surfactants, particularly cocamidopropyl betaine
  • amphoteric surfactants are present preferably in an amount of from 0.2 to 10% by weight based on the total weight of the composition. More preferably the level of non-ionic surfactant is from 0.5 to 7 wt% of the total composition, most preferably from 1 to 5 wt% of the total composition. It is preferred if the weight ratio of amphoteric surfactant to polymeric deposition aid is from 5:1 to 40:1 , more preferably from 10:1 to 30:1 .
  • amphoteric surfactant is at least 75wt% of the total weight of the surfactant in the composition.
  • surfactants such as anionic and amphoteric surfactants, may be present it is preferred if they are limited to levels below 0.5 wt% of the total composition preferably less than 0.1 wt% of the total composition. This is particularly the case with anionic surfactants.
  • the oral care composition comprises water, thickener and abrasive.
  • Suitable thickeners include silicas and calcium carbonate.
  • the preferred thickener is silica.
  • Preferred abrasive materials include silicas, aluminas, calcium carbonates, dicalcium phosphates, calcium pyrophosphates, hydroxyapatites, trimetaphosphates, insoluble hexametaphosphates and so on, including agglomerated particulate abrasive materials, usually in amounts between 3 and 60% by weight of the oral care composition.
  • the most preferred abrasives are calcium carbonate and silica, especially silica.
  • compositions according to the invention may comprise further ingredients which are common in the art, such as: antimicrobial agents, e.g. Triclosan, chlorhexidine, copper, zinc, and stannous salts such as zinc citrate, zinc sulphate, zinc glycinate, sodium zinc citrate and stannous
  • antimicrobial agents e.g. Triclosan, chlorhexidine, copper, zinc, and stannous salts such as zinc citrate, zinc sulphate, zinc glycinate, sodium zinc citrate and stannous
  • starch starch, sucrose, water or water/alcohol systems etc.; humectants such as glycerol, sorbitol, propyleneglycol, xylitol, lactitol etc.; binders and thickeners such as sodium carboxymethyl-cellulose, xanthan gum, gum arabic etc. as well as synthetic polymers such as polyacrylates and carboxyvinyl polymers such as Carbopol®; buffers and salts to buffer the pH and ionic strength of the oral care composition; and other optional ingredients that may be included are e.g. bleaching agents such as peroxy compounds e.g. potassium peroxydiphosphate, effervescing systems such as sodium bicarbonate/citric acid systems, colour change systems, and so on.
  • bleaching agents such as peroxy compounds e.g. potassium peroxydiphosphate, effervescing systems such as sodium bicarbonate/citric acid systems, colour change systems, and so on.
  • Liposomes may also be used to improve delivery or stability of active ingredients.
  • the oral care compositions may be in any form common in the art, e.g. toothpaste, gel, mousse, aerosol, chewing gum, lozenge, powder, cream, and may also be formulated into systems for use in dual-compartment type dispensers.
  • Preferred forms are toothpastes.
  • amounts are percentages by weight unless otherwise stated.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition pour soins buccaux comprenant un tensioactif amphotère et un pigment ayant un angle de teinte, h, dans le système CIELAB compris entre 220 et 320 degrés.
PCT/EP2018/054573 2017-05-12 2018-02-23 Compositions pour soins buccaux WO2018206172A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17170918 2017-05-12
EP17170918.1 2017-05-12

Publications (1)

Publication Number Publication Date
WO2018206172A1 true WO2018206172A1 (fr) 2018-11-15

Family

ID=58709317

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2018/054573 WO2018206172A1 (fr) 2017-05-12 2018-02-23 Compositions pour soins buccaux

Country Status (1)

Country Link
WO (1) WO2018206172A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1935395A1 (fr) 2006-12-20 2008-06-25 Unilever Plc Compositions de protection orale
WO2014117904A2 (fr) * 2013-02-01 2014-08-07 Unilever Plc Compositions de soin buccal
WO2015095709A1 (fr) 2013-12-20 2015-06-25 Colgate-Palmolive Company Produit de soin oral pour blanchiment des dents à base de particules de silice de structure cœur-écorce
WO2015099638A1 (fr) * 2013-12-23 2015-07-02 Colgate-Palmolive Company Produit d'hygiène buccale pour le blanchiment des dents
WO2016099544A1 (fr) 2014-12-19 2016-06-23 Colgate-Palmolive Company Composition orale pour le blanchiment des dents

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1935395A1 (fr) 2006-12-20 2008-06-25 Unilever Plc Compositions de protection orale
WO2014117904A2 (fr) * 2013-02-01 2014-08-07 Unilever Plc Compositions de soin buccal
WO2015095709A1 (fr) 2013-12-20 2015-06-25 Colgate-Palmolive Company Produit de soin oral pour blanchiment des dents à base de particules de silice de structure cœur-écorce
WO2015099638A1 (fr) * 2013-12-23 2015-07-02 Colgate-Palmolive Company Produit d'hygiène buccale pour le blanchiment des dents
WO2016099544A1 (fr) 2014-12-19 2016-06-23 Colgate-Palmolive Company Composition orale pour le blanchiment des dents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
H. ZOLLINGER: "Colour Chemistry. 3rd ed.", WILEY-VCH, pages: 57

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